@TOME V2.3
(Nov 2016)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
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Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
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Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu17180: (2016-06-27 )
MRNNDNIRILTNPSVSHGEPLHISEKQPATIPEVLYRTATELGDTKGIIYLQPDGTEVYQSYRRLWDDGLRIAKGLRQSGLKAKQSVILQLGDNSQLLPAFWGCVLTGVVPAPLAVPPTYAESSSGTQKLKDAWTLLDKPAVITDRGMHQEMLDWAKEQGLEGFRAIIVEDLLSAEADTDWHQSSPEDLALLLLTSGSTGTPKAVMLNHRNIMSMVKGIIQMQGFTREDITFNWMPFDHVGGIGMLHLRDVYLGCQEINVSSETILMEPLKWLDWIDHYRASVTWAPNFAFGLVTDFAEEIKDKKWDLSSMRYMLNGGEAMVAKVGRRILELLEPHGLPADAIRPAWGMSETSSGVIFSHEFTRAGTSDDDHFVEIGSPIPGFSMRIVNDHNELVEEGEIGRFQVSGLSVTSGYYQRPDLNESVFTEDGWFETGDLGFLRNGRLTITGRTKDAIIINGINYYSHAIESAVEELPEIETSYTAACAVRLGQNSTDQLAIFFVTSAKLNDEQMSQLLRNIQSHVSQVIGVTPEYLLPVQKEEIPKTAIGKIQRTQLKTSFENGEFDHLLHKPNRMNDAVQDEGIQQADQVKRVREEIQKHLLTCLTEELHVSHDWVEPNANIQSLGVNSIKMMKLIRSIEKNYHIKLTAREIHQYPTIERLASYLSEHEDLSSLSADKKGTDTYKTEPERSQATFQPLSEVQKGLWTLQKMSPEKSAYHVPLCFKFSSGLHHETFQQAFGLVLNQHPILKHVIQEKDGVPFLKNEPALSIEIKTENISSLKESDIPAFLRKKVKEPYVKENSPLVRVMSFSRSEQEHFLLVVIHHLIFDGVSSVTFIRSLFDTYQLLLKGQQPEKAVSPAIYHDFAAWEKNMLAGKDGVKHRTYWQKQLSGTLPNLQLPNVSASSVDSQFREDTYTRRLSSGFMNQVRTFAKEHSVNVTTVFLSCYMMLLGRYTGQKEQIVGMPAMVRPEERFDDAIGHFLNMLPIRSELNPADTFSSFISKLQLTILDGLDHAAYPFPKMVRDLNIPRSQAGSPVFQTAFFYQNFLQSGSYQSLLSRYADFFSVDFVEYIHQEGEYELVFELWETEEKMELNIKYNTGLFDAASISAMFDHFVYVTEQAMLNPSQPLKEYSLLPEAEKQMILKTWNATGKTYPYITFHELFEQQAKKTPDRAAVSYEGQTLTYRELDEKSTQLAIYLQAHGVGPDRLAGIYVDRSLDMLVGLLAILKAGGAYVPLDPSYPAERLEYMLEDSEVFITLTTSELVNTLSWNGVTTALLDQDWDEIAQTASDRKVLTRTVTPENLAYVIYTSGSTGKPKGVMIPHKALTNFLVSMGETPGLTAEDKMLAVTTYCFDIAALELFLPLIKGAHCYICQTEHTKDVEKLKRDIRAIKPTVMQATPATWKMLFYSGWENEESVKILCGGEALPETLKRYFLDTGSEAWNMFGPTETTIWSAVQRINVECSHATIGRPIANTQIYITDSQLAPVPAGVPGELCIAGDGVAKGYYKKEELTDSRFIDNPFEPGSKLYRTGDMARWLTGGRIEYIGRIDNQVKIRGFRIELGDIESRLSEHPGILECVVVADMDNLAAYYTAKHANASLTARELRHFVKNALPAYMVPSYFIQLDHMPLTPNGKIDRNSLKNIDLSGEQLKQRQTSPKNIQDTVFTIWQEVLKTSDIEWDDGFFDVGGDSLLAVTVADRIKHELSCEFSVTDLFEYSTIKNISQYITEQRMGDASDHIPTDPAAHIEDQSTEMSDLPDYYDDSVAIIGISCEFPGAKNHDEFWENLRDGKESIAFFNKEELQRFGISKEIAENADYVPAKASIDGKDRFDPSFFQISPKDAEFMDPQLRMLLTHSWKAIEDAGYAARQIPQTSVFMSASNNSYRALLPSDTTESLETPDGYVSWVLAQSGTIPTMISHKLGLRGPSYFVHANCSSSLIGLHSAYKSLLSGESDYALVGGATLHTESNIGYVHQPGLNFSSDGHIKAFDASADGMIGGEGVAVVLLKKAADAVKDGDHIYALLRGIGVNNDGADKVGFYAPSVKGQADVVQQVMNQTKVQPESICYVEAHGTGTKLGDPIELAALTNVYRQYTNKTQFCGIGSVKTNIGHLDTAAGLAGCIKVVMSLYHQELAPSVNYKEPNPNTDLASSPFYVVDQKKTLSREIKTHRAALSSFGLGGTNTHAIFEQFKRDSDKGKIDGTCIVPISAKNKERLQEYAEDILAYLERRGFENSQLPDFAYTLQVGREAMEHRVVFIADHVNELKQRLTDFINGNTAIEGCFQGSKHNAREVSWLTEDEDSAELIRKWMAKGKVNKLAEMWSKGAHIDWMQLYKGERPNRMSLPTYPFAKERYWPSQDDRKPVAQISGNQTGIGSIHPLLHQNTSDFSEQKFSSVFTGDEFFLRDHVVRGKPVLPGVAYLEMAYAAINQAAGSEIGQDVRIRLNHTVWVQPVVVDRHSAQVDISLFPEEDGKITFDIYSTQEDGDDPVIHSQGSAELASAAETPVADLTEMSRRCGKGKMSPDQFYEEGRSRGMFHGPAFQGIKNVNIGNREVLAQLQLPEIVSGTNEQFVLHPSIMDSALQTATICIMQELTDQKLILPFALEELEVIKGCSSSMWAYARLSDSDHSGGVVQKADIDVIDESGTVCVRIKGFSTRVLEGEVHTSKPSTRHERLMLEPVWEKQNEEREDEDLSYTEHIIVLFETERSVTDSIASHMKDARVITLNEAVGHIAERYQCYMQNIFELLQSKVRKLSAGRIIIQAIVPLEKEKQLFAGVSGLFKTAEIEFSKLTAQVIEIEKPEEMIDLHLKLKDDSRRPFDKQIRYEAGYRFVKGWREMVLPSADTLHMPWRDEGVYLITGGAGSLGLLFAKEIANRTGRSTIVLTGRSVLSEDKENELEALRSIGAEVVYREADVSDQHAVRHLLEEIKERYGTLNGIIHGAGSSKDRFIIHKTNEEFQEVLQPKVSGLLHVDECSKDFPLDFFIFFSSVSGCLGNAGQADYAAANSFMDAFAEYRRSLAASKKRFGSTISFNWPLWEEGGMQVGAEDEKRMLKTTGMVPMPTDSGLKAFYQGIVSDKPQVFVMEGQLQKMKQKLLSAGSKAKRNDQRKADQDQGQTRKLEAALIQMVGAILKVNTDDIDVNTELSEYGFDSVTFTVFTNKINEKFQLELTPTIFFEYGSVQSLAEYVVAAYQGEWNQDATAKGKDERTNLVHSLSSLEASLSNMVSAILKVNSEDIDVNTELSEYGFDSVTFTVFTNKINEEFQLELTPTIFFEYGSLHSLAEYLTVEHGDTLVQEREKPEGQEELQTKSSEAPKITSRRKRRFTQPIIAKAERNKKQAADFEPVAIVGISGRFPGAMDIDEFWKNLEEGKDSITEVPKDRWDWREHYGNPDTDVNKTDIKWGGFIDGVAEFDPLFFGISPREADYVDPQQRLLMTYVWKALEDAGCSPQSLSGTGTGIFIGTGNTGYKDLFHRANLPIEGHAATGHMIPSVGPNRMSYFLNIHGPSEPVETACSSSLVAIHRAVTAMQNGDCEMAIAGGVNTILTEEAHISYSKAGMLSTDGRCKTFSADANGYVRGEGVGMVMLKKLEDAERDGNHIYGVIRGTAENHGGRANTLTSPNPKAQADLLVRAYRQADIDPSTVTYIEAHGTGTELGDPIEINGLKAAFKELSNMRGESQPDVPDHRCGIGSVKSNIGHLELAAGISGLIKVLLQMKHKTLVKSLHCETLNPYLQLTDSPFYIVQEKQEWKSVTDRDGNELPRRAGISSFGIGGVNAHIVIEEYMPKANSEHTATEQPNVIVLSAKNKSRLIDRASQLLEVIRNKKYTDQDLHRIAYTLQVGREEMDERLACVAGTMQELEEKLQAFVDGKEETDEFFRGQSHRNKETQTIFTADEDMALALDAWIRKRKYAKLADLWVKGVSIQWNTLYGETKPRLISLPSYPFAKDHYWVPAKEHSERDKKELVNAIEDRAACFLTKQWSLSPIGSAVPGTRTVAILCCQETADLAAEVSSYFPNHLLIDVSRIENDQSDIDWKEFDGLVDVIGCGWDDEGRLDWIEWVQRLVEFGHKEGLRLLCVTKGLESFQNTSVRMAGASRAGLYRMLQCEYSHLISRHMDAEEVTDHRRLAKLIADEFYSDSYDAEVCYRDGLRYQAFLKAHPETGKATEQSAVFPKDHVLLITGGTRGIGLLCARHFAECYGVKKLVLTGREQLPPREEWARFKTSNTSLAEKIQAVRELEAKGVQVEMLSLTLSDDAQVEQTLQHIKRTLGPIGGVIHCAGLTDMDTLAFIRKTSDDIQRVLEPKVSGLTTLYRHVCNEPLQFFVLFSSVSAIIPELSAGQADYAMANSYMDYFAEAHQKHAPIISVQWPNWKETGMGEVTNQAYRDSGLLSITNSEGLRFLDQIVSKKFGPVVLPAMANQTNWEPELLMKRRKPHEGGLQEAALQSPPARDIEEADEVSKCDGLLSETQSWLIDLFTEELRIDREDFEIDGLFQDYGVDSIILAQVLQRINRKLEAALDPSILYEYPTIQRFADWLIGSYSERLSALFGGRISDASAPLENKIEAEASVPGKDRALTPQIQAPAILSPDSHAEGIAVVGLSCRFPGAETLESYWSLLSEGRSSIGPIPAERWGCKTPYYAGVIDGVSYFDPDFFLLHEEDVRAMDPQALLVLEECLKLLYHAGYTPEEIKGKPVGVYIGGRSQHKPDEDSLDHAKNPIVTVGQNYLAANLSQFFDVRGPSVVVDTACSSALVGMNMAIQALRGGDIQSAIVGGVSLLSSDASHRLFDRRGILSKHSSFHVFDERADGVVLGEGVGMVMLKTVKQALEDGDIIYAVVKAASVNNDGRTAGPATPNLEAQKEVMKDALFKSGKKPEDISYLEANGSGSIVTDLLELKAIQSVYRSGHSSPLSLGSIKPNIGHPLCAEGIASFIKVVLMLKERRFVPFLSGEKEMAHFDQQKANITFSRALEKWTDSQPTAAINCFADGGTNAHVIVEAWEKDEKHAIKRSPISPPQLKKRMLSPGEPKLEAETSKMTAANIWDTYEVEV
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180..-.....190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720--.......730........740.......750....-....760.......770.......----780.......-----790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900...------....910....--...920......---.930.......940.......950.......960......--.--970.......980.......990.......1000......1010......1020......1030-......1040.-.....1050.-------..-----...1060.....-...1070......1080.-......1090......1100......1110......1120......1130......1140......1150--......1160......1170..-....1180......1190......1200......1210......1220......1230......1240......1250......1260-..---......1270....---------....1280......1290.....------.1300......1310......1320......1330..---....1340......1350......1360......1370......1380......1390......1400..-....1410....-----..--.1420-..-.....1430..--..--..1440......1450-..---......--.---1460....-....1470---........1480.......1490......1500......1510......1520..-.....1530......1540......1550......1560......1570......1580-.-----.-----.....1590.......1600......1610......1620......1630......1640......1650.....-.1660......1670......1680......1690......1700......1710......1720......1730......1740......1750......1760......1770......1780......1790......1800...--...1810......1820......1830......1840......1850......1860.....--.1870......1880......1890......1900......1910......1920......1930......1940......1950......1960......1970......1980......1990......2000......2010......2020......2030......2040......2050......2060......2070......2080......2090--.......2100......2110......2120......2130......2140......2150......2160-----.......2170......2180......2190......2200......2210......2220......2230......2240......2250......2260......2270......2280.....-.2290......2300......2310......2320......2330......2340......2350......2360......2370......2380......2390......2400......2410......2420......2430......2440......2450......2460......2470......2480......2490......2500......2510......2520......2530......2540......2550......2560......2570......2580......2590......2600......2610......2620......2630......2640......2650......2660......2670......2680......2690......2700......2710......2720......2730......2740......2750......2760......2770......2780......2790......2800......2810......2820......2830......2840......2850......2860......2870......2880......2890......2900......2910......2920......2930......2940......2950......2960......2970......2980......2990......3000......3010......3020......3030......3040......3050......3060......3070......3080......3090......3100......3110......3120......3130......3140......3150......3160......3170......3180......3190......3200......3210......3220......3230......3240......3250......3260......3270......3280......3290......3300......3310......3320......3330......3340......3350......3360......3370......3380......3390......3400......3410......3420......3430......3440......3450-------.........3460......3470......3480......3490......3500......3510......3520......3530......3540......3550......3560......3570......3580......3590......3600......3610......3620......3630......3640......3650......3660......3670......3680......3690......3700......3710......3720......3730......3740......3750......3760......3770......3780......3790......3800......3810......3820......3830......3840......3850......3860......3870......3880......3890......3900......3910......3920.....-.3930......3940......3950......3960......3970......3980......3990......4000......4010......4020......4030......4040......4050......4060......4070......4080......4090......4100......4110......4120......4130......4140......4150......4160......4170......4180......4190......4200......4210......4220......4230......4240......4250......4260......4270......4280......4290......4300......4310......4320......4330......4340......4350......4360......4370......4380......4390......4400......4410......4420......4430......4440......4450......4460......4470......4480......4490......4500......4510......4520......4530......4540......4550......4560......4570......4580......4590......4600......4610......4620......4630......4640......4650......4660......4670......4680......4690......4700......4710......4720......4730......4740......4750......4760......4770......4780......4790......4800......4810......4820......4830......4840......4850......4860......4870......4880......4890......4900......4910......4920......4930......4940......4950......4960......4970......4980......4990......5000......5010......5020......5030......5040
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MRNND
N
I
R
I
L
TNPSVSHGE
P
L
HISEKQPA
T
I
P
E
V
L
Y
R
T
A
T
ELGDTK
G
I
I
Y
LQPD
G
T
E
V
Y
Q
S
Y
R
R
L
W
DD
G
L
R
I
A
K
G
L
R
Q
SGL
K
A
K
Q
S
V
I
L
Q
LGDNS
Q
L
L
P
A
F
W
G
C
V
L
TGVVPAPLAVPPTYAESSSG
T
Q
K
L
K
D
A
W
T
LLDKPAVITDR
G
M
H
Q
E
M
L
D
W
A
K
E
QG
L
E
G
F
R
A
I
I
V
E
D
L
L
SAEADTDWHQS-SPE
D
L
A
L
L
L
L
TSGSTGT
P
K
A
V
M
LN
H
R
N
I
M
S
M
V
K
G
I
I
Q
MQGFTRED
I
T
F
NWMPFDHVGG
I
G
M
L
H
L
R
D
V
YL
G
C
QEINVSS
E
T
I
L
M
E
P
L
K
W
L
D
W
I
D
H
YR
A
S
V
T
WAP
N
F
A
F
G
L
V
T
D
F
A
E
E
I
K
DKKW
D
L
S
S
M
R
Y
M
LNG
G
E
A
M
V
A
K
V
G
R
R
I
L
E
L
LEPHGL
P
A
D
AIRPAWGMSETSS
G
V
I
F
S
HEFTRAGTSDDD
H
F
V
EIGSPIPG
F
S
M
R
I
VND
H
N
E
L
VEEGEI
G
R
F
Q
V
S
G
L
S
VTSGYYQRPDLNESVFTEDGWFETGDL
G
F
LRNG
R
L
T
I
TGRTK
D
A
I
I
IN
G
I
N
Y
Y
S
H
A
I
E
S
A
V
E
ELPEIETSY
T
A
A
C
A
V
RLGQNST
D
Q
L
A
I
F
F
V
TSAKL
N
D
E
Q
M
S
Q
L
L
R
N
I
Q
S
H
V
S
Q
V
IGV
T
P
E
Y
LLPV
Q
K
EEI
P
K
T
A
I
G
K
I
Q
R
T
Q
L
KTSFENG
E
F
D
H
L
LHKPNRMN
D
A
V
Q
D
EG
I
Q
Q
A
D
Q
V
K
R
V
R
E
E
I
Q
K
H
L
L
T
C
L
T
E
E
LHVSHDWVEPNANIQSLGV
N
S
I
K
M
M
K
L
I
R
S
I
EKN
Y
H
I
K
L
T
A
R
E
I
HQYP
T
I
E
R
L
A
S
Y
L
S
E
H
E
D
L
S
S
LSADKKGTDTYKTEPERSQATFQ
P
L
S
E
V
Q
K
G
L
W
T
L
Q
KMSPEKS
A
Y
H
V
P
L
C
F
--KFSSGL
H
H
-
E
T
F
Q
Q
A
F
G
L
VLNQ
H
P
I
L
K
H
V
-
I
Q
EKD-GVPFLKNEP
A
L
S
I
E
I
KTE
N
I
S
S
L
K
----ES
D
I
P
A
F
L
R
K
-----
K
V
KEPYVKENS
P
L
V
R
V
M
SFSRSEQE
H
F
L
L
V
V
I
H
H
L
I
F
DG
V
S
S
V
T
F
I
R
S
L
F
D
T
Y
Q
L
L
LKGQQPEKAV
S
P
A
I
Y
H
D
F
A
A
W
E
K
N
MLAGKDGV
K
H
R
T
Y
W
Q
K
Q
LSGTLPNLQLPNVS
A
S
S
V
D
------
S
Q
F
R
E
D
T
Y
T
R
R
--
L
S
S
G
F
M
N
Q
V
R
T
F
---
A
K
EHSV
N
V
T
T
V
F
L
S
C
Y
M
M
L
L
G
RYTGQ
K
E
QIVGMPAMV
R
P
E
--
E
--
R
F
D
D
A
I
G
H
F
L
N
MLPIRSEL
N
P
A
D
T
F
S
S
F
I
S
K
L
Q
L
T
ILDGLDHAAY
P
F
P
K
M
V
R
DLNIPRSQAGS
P
-
V
F
Q
T
A
F
F
Y
Q
N
F
-
L
QSG
S
Y
Q
S
L
L
-------
S
R
-----
Y
A
D
F
--
F
S
V
D
F
V
-
E
Y
I
H
QEG
E
Y
E
L
V
F
ELW-E-TE
E
K
M
E
L
N
I
K
YNTGLF
D
A
A
S
I
S
A
M
F
D
H
F
V
Y
V
T
E
Q
AMLNPSQ
P
L
K
E
YSLL
P
E
A
E
K
Q
M
I
L
K
TWNATGKTY
P
Y
--
I
T
F
H
E
L
F
E
Q
Q
A
KKTPD
R
A
A
V
SY-EG
Q
T
L
T
Y
R
ELDEKS
T
Q
L
A
I
Y
L
Q
AHGV
G
P
D
R
L
A
G
I
Y
VD
R
S
L
D
M
L
V
G
L
L
A
I
L
KAGG
A
Y
VPLDPSY
P
A
E
R
L
E
Y
M
LEDS
E
V
F
I
T
L
T
T
S
E
L
---
V
N
---
T
LSWNGV--
T
T
A
L
L
---------DQ
D
W
D
E
I
A
Q
T
ASD
R
K
V
L
T
R
TVTP------E
N
L
A
Y
V
I
Y
TSGSTGKPK
G
V
M
I
P
H
K
A
L
T
N
F
L
V
SMGETP---GLTAED
K
M
L
A
V
T
T
Y
C
F
D
I
A
A
L
E
L
F
L
P
L
IKG
A
H
C
Y
I
CQTE
H
T
K
D
V
E
K
L
K
R
D
I
R
A
IK
P
T
V
MQATPA
T
W
K
M
L
F
-
Y
SGWE-NE
E
S
V
K
-----
I
L
--CGG
E
--
A
L
-
P
E
T
L
K
R
Y
F
LDT--GS--EAWNMFGP
T
E
T
T
I
----
W
S
---
A
V
Q
R
I
N
--
V
---
E
--CSHAT-IGRPIA-----N
T
Q
I
Y
I
TDSQ-LAPVPAGVPG
E
L
C
IAGDGVAKGY
Y
K
K
E
ELTDSRFIDNPFE-PGS-
K
L
YRTG
D
M
A
R
WLTGG
R
I
E
Y
I
GRID
N
Q
V
K
I
R
G
F
R
I
E
L
G
D
I
E
S
R
L
S
EHPG
I
L
E
C
V
V
V
ADM--D-----
N
-----
L
A
A
Y
Y
TA-KHANASL
T
A
R
E
L
R
H
F
V
K
NAL
P
A
Y
M
V
P
S
Y
F
I
Q
LDHMPLTPNGKIDRNSLKNIDL
S
G
E
Q
L
K
Q
RQTSPKN-
I
Q
D
T
V
F
T
I
W
Q
E
V
L
KTSDIEWDDG
F
F
DVGGD
S
L
L
A
V
T
V
A
D
R
I
K
H
E
LSC
E
F
S
V
T
D
L
F
E
Y
S
T
I
K
N
I
S
Q
Y
I
T
E
Q
RMGDASDHIPTDPAAHIEDQSTEMSDLPDYYDD
S
V
A
I
I
G
I
S
C
EFPGAK
N
H
D
E
F
W
E
N
L
RDG
K
E
S
I
AFF
N
K
E
E
L
Q
R
FGI
S
--
K
E
I
AENADYVPAKASIDGKDRFDPS
F
F
Q
ISPKDAEFM
D
P
Q
L
R
M
L
L
THS
W
K
A
I
E
DA
G
Y
A
A
RQI--PQ
T
S
V
F
M
SASNN
S
Y
R
A
LLPSDTTESLETPDG
Y
V
S
W
V
LAQSGT
I
P
T
M
I
S
H
KLGLRGP
S
Y
F
V
HANCS
S
S
L
I
G
L
H
S
A
Y
K
S
L
LSGES
D
Y
A
L
VG
G
A
T
L
HTESNIG
Y
V
HQPGLNFSSDG
H
I
K
A
FDASADGMIGGE
G
V
A
V
V
L
L
K
K
A
A
D
AVKD
G
D
H
I
Y
A
L
L
R
GIGVNNDGADKV
G
F
YAPSVKG
Q
A
D
V
V
Q
Q
V
M
N
QTKVQPE
S
I
C
Y
V
E
AHGTGTKLGD
P
I
E
L
A
A
L
T
N
V
Y
R
Q
YTN---KT
Q
F
CGIGSVKTNIGHL
D
T
A
A
G
L
A
G
C
I
K
V
V
M
S
L
Y
H
Q
E
LAPSVNYKEPNPNTDLASS
P
F
Y
V
V
D
Q
K
K
T
L
S
R
E
------
I
K
T
H
R
A
A
L
S
S
FGLGGT
N
T
H
A
I
F
E
Q
F
KRDSDKGKID
G
T
C
I
V
P
ISAK
N
K
E
R
L
Q
E
Y
A
E
D
I
L
A
Y
L
E
RRGFENSQLP
D
F
A
Y
T
L
Q
V
G
R
E
A
M
EH
R
V
V
F
I
A
D
H
V
N
E
L
K
Q
R
L
T
D
F
INGN
T
A
I
E
GCFQGSKHNA
R
E
-
V
S
W
LTEDE
D
S
A
E
L
I
R
K
W
M
AKG
K
V
N
K
L
A
E
M
W
SKGAH
I
D
W
M
Q
L
YKGERPNRMSLPTYPFAKERYWPSQDDRKP
V
A
Q
ISGNQTGI
G
S
I
H
P
L
LHQNTS
D
F
S
E
Q
K
F
S
S
VFTG
D
E
F
F
L
R
DHVVRGKPVL
P
G
V
A
Y
L
E
M
A
Y
A
A
I
N
Q
A
A
G
S
EIG
Q
D
V
R
I
R
LN
H
T
V
W
V
Q
P
V
V
V
DRHS
A
Q
V
D
I
S
L
FPEED
G
K
I
T
F
D
I
Y
STQEDGDD
P
V
IHSQG
S
A
E
L
A
SAAETP
V
A
D
L
T
E
M
S
R
RCGKGKM
S
P
D
Q
F
Y
E
E
G
RSRGMFHGPAFQGIKNVNIG
N
R
E
V
L
A
Q
LQL
P
E
IVSGTNE
Q
F
V
L
H
P
S
I
M
D
S
A
L
Q
T
A
T
I
C
I
M
Q
E
LTDQ
K
L
I
L
P
F
A
L
E
E
L
E
V
I
KGCSSS
M
W
A
Y
A
RLSDSDHSGG
V
V
Q
KAD
I
D
V
IDESG
T
V
C
V
R
I
KG
F
S
T
R
V
L
EGEVHTSKPSTRH
E
R
L
MLEPVWEKQNEEREDEDLSY
T
E
H
I
I
V
L
F
ETE
R
S
V
T
D
S
I
A
S
H
M
KD
A
R
V
I
T
L
N
E
A
V
G
H
I
A
E
R
Y
Q
C
Y
M
Q
N
I
F
E
L
L
Q
S
K
V
R
K
LSAG
R
I
I
I
Q
A
IVP
L
E
K
E
K
Q
L
F
A
G
V
S
G
L
F
K
T
A
E
I
E
F
S
K
L
T
A
Q
V
I
EIEK
P
E
E
M
I
D
L
H
L
K
LKDDSRRP
F
D
K
Q
I
R
Y
E
A
G
Y
R
F
V
K
G
W
R
E
MVLPSADTLHMPWRDE
G
V
Y
L
I
TGGAG
S
L
G
L
L
F
A
K
E
I
A
NRTG
R
S
T
I
V
LT
G
R
S
VLSEDK
E
N
E
L
E
A
L
R
S
I
G
A
E
V
V
Y
READVS
D
Q
H
A
V
R
H
L
L
E
E
I
K
E
R
YGTLN
G
I
I
HGAGSSK
D
R
F
I
I
HKT
N
E
E
F
Q
E
V
L
Q
P
K
V
S
G
L
L
H
V
D
ECSKDFPL
D
F
F
I
F
F
S
S
V
S
G
CLGNAGQ
A
D
Y
A
A
A
N
S
F
M
D
A
F
A
E
Y
R
R
S
L
A
A
S
K
K
RFG
S
T
I
SFNWPLWEEG
G
M
QVG
A
E
D
E
K
R
M
L
K
TTGMVPMPT
D
S
G
L
K
A
F
Y
Q
G
I
VSDKP
Q
V
F
V
ME
G
Q
L
Q
K
M
K
Q
K
L
L
SAGSKAKRNDQRKADQDQGQ
T
R
K
L
E
A
A
L
I
Q
M
V
G
A
I
L
K
VNTDDIDVNT
E
L
S
EYGFD
S
V
T
F
T
V
F
TNKIN
E
K
F
Q
L
E
LT
P
T
I
F
F
EYG
S
V
Q
S
L
A
E
Y
V
V
A
A
YQGEWNQDATAKGK
D
E
R
T
N
L
V
H
S
L
S
S
L
E
A
S
L
S
N
M
V
S
A
I
L
KVNSEDIDVNT
E
L
S
EYGFD
S
V
T
F
T
V
F
TNKIN
E
E
F
Q
L
E
LT
P
T
I
F
F
EYG
S
L
H
S
L
A
E
Y
L
T
VEH
G
D
T
L
V
Q
E
REKPE
G
Q
E
E
L
Q
TKSSEAP
K
I
T
S
R
R
K
RRFTQ
P
I
I
A
K
A
ERNKKQAADFE
P
V
A
I
V
G
ISGRFPGAM
D
I
D
E
F
W
K
N
L
E
EG
K
D
S
I
T
EVPKDRW
D
W
R
E
HYGNPDTDVNKT
D
I
KWGGFID
G
V
AEFD
P
L
F
FGISPREADYV
D
P
Q
Q
R
L
L
M
T
Y
V
W
K
A
L
E
DAGCSPQSLS----------GTG
T
G
I
F
I
GTGNT
G
Y
K
D
L
F
H
RANLPIEGHAATGHMIPSVGPN
R
M
S
Y
F
L
N
IHGPS
E
P
V
E
T
A
C
S
S
S
L
V
A
I
H
R
A
V
T
A
MQNGDC
E
M
A
IAGGVN
T
I
LTEEAHISYSKAGMLSTDGR
C
K
T
FSADAN
G
Y
V
RGEG
V
G
M
V
M
L
K
K
L
E
D
AERDG
N
H
I
Y
G
V
I
RGTAENHGGRANTLTSPNP
K
A
Q
A
D
L
L
V
R
A
Y
R
QADIDPS
T
V
T
Y
I
E
AHGTGTELGD
P
I
EIN
G
L
K
A
A
F
K
E
L
S
N
MRGESQPDVPDHRCGIG
S
V
KSNIG
H
L
E
L
A
A
G
I
S
G
L
I
K
V
L
L
Q
M
K
H
K
T
L
V
K
S
L
H
CETLN
P
Y
L
Q
LTDS
P
F
Y
I
V
Q
E
K
Q
E
W
K
S
VTDRDGNEL
P
R
RAGISSFGIGG
V
N
A
H
I
V
I
E
E
YMPKANSEHTATEQP
N
V
I
V
L
SAK
N
K
S
R
L
I
D
R
A
S
Q
L
L
E
V
I
RNKKY
T
D
Q
D
L
H
R
I
A
Y
T
L
QV
G
R
E
E
M
D
E
R
L
A
C
V
A
G
T
M
Q
E
L
E
E
K
L
Q
A
F
VDG
K
E
E
T
D
E
F
FRGQSHRNKE
T
Q
T
I
F
TADE
D
M
A
L
A
L
D
A
W
I
R
K
R
K
Y
A
K
L
A
D
L
W
VKG
V
S
I
Q
W
N
TLYGE-TK
P
R
L
ISLPSYPFAKD
H
Y
W
V
P
A
K
E
HS
E
R
D
K
K
E
L
V
N
A
I
E
D
R
A
A
C
F
L
TKQWSLSPIGSAVPGT
R
T
V
A
I
L
C
C
Q
E
T
A
D
L
A
A
E
V
S
S
YFPN
H
L
L
I
D
V
S
R
IENDQSDI
D
W
K
E
FDG
L
V
D
V
IGCGWDDEGR
L
D
W
I
E
W
V
Q
R
L
V
EF
G
H
KEG
L
R
L
L
C
V
T
K
G
L
E
S
F
QNT
S
V
R
MAGA
S
R
A
G
L
Y
R
M
L
Q
C
E
Y
S
H
L
I
S
RHM
D
A
E
E
V
T
D
H
R
R
L
A
K
L
I
A
D
E
FYSDSYD
A
E
V
C
YRDGL
R
Y
Q
A
F
L
K
AHPETGKATEQSAVFPKD
H
V
L
L
I
TGGT
R
G
I
G
L
L
C
A
R
H
F
A
E
C
YG
V
K
K
L
V
LTGREQLP
P
R
E
E
W
A
R
FKTSN
T
S
L
A
E
K
I
Q
A
V
R
E
LEAKG
V
Q
V
E
M
L
S
L
TLSD
D
A
Q
V
E
Q
T
L
Q
H
I
K
R
T
LGPIG
G
V
I
HCAGLT
D
M
D
T
L
A
F
I
RK
T
S
D
D
I
Q
R
V
LEPKV
S
G
L
T
T
L
Y
R
H
V
CNE
P
L
Q
F
F
V
L
F
S
S
V
S
A
I
I
P
ELSAGQ
A
D
Y
A
M
A
N
S
Y
M
D
Y
F
A
E
A
H
QKHA
P
I
I
S
V
QWPNWKETG
M
G
E
V
T
N
Q
A
YRDS
G
L
L
S
ITN
S
E
G
L
R
F
L
D
Q
I
V
SKKFG
P
V
V
L
PAMANQTNW
E
P
E
L
L
M
K
RRKPHEGG
L
Q
E
A
ALQSPPAR
D
I
E
E
A
D
E
V
S
K
C
D
G
L
L
S
E
T
Q
S
W
L
I
D
L
F
T
E
E
LRIDREDFEI
D
G
L
F
Q
DYGV
D
S
I
I
L
A
Q
V
L
Q
R
I
N
R
K
L
E
AAL
D
P
S
I
L
YEYP
T
I
Q
R
F
A
D
W
L
I
G
S
Y
S
E
R
L
S
A
L
FGGRISDASAPLENKIEAEASVPGKDRALTPQIQA
P
A
I
LSPDSHAE
G
I
A
V
V
G
L
S
CRFP
G
A
E
T
L
E
S
Y
W
S
L
L
SEGRSSIGPI
P
A
ERWGCKTP
Y
Y
A
G
VIDGVSYFDP
D
F
F
L
L
HEEDVRAM
D
P
Q
A
L
L
V
L
E
E
C
L
K
L
L
YHAGY
T
P
E
EIKGK
P
V
G
V
Y
IGGRSQHKPDEDSLDHAKN
P
I
V
TV
G
Q
N
Y
L
A
A
N
L
S
Q
F
FDVRGP
S
V
V
V
DTA
C
S
S
A
L
V
G
M
N
M
A
I
Q
A
LRGG
D
I
Q
S
A
I
V
G
G
V
S
L
L
SSDASH
R
L
F
D
RRGILSKHS
S
F
H
V
F
DERAD
G
V
V
LGEG
V
G
M
V
M
L
K
T
V
K
Q
A
LEDG
D
I
I
Y
A
V
V
K
A
A
SVNNDGRTAGPATP
N
L
E
A
Q
K
E
V
M
K
D
A
L
FKSGKKPED
I
S
Y
L
EANGS
G
S
I
V
T
D
L
L
E
L
K
A
I
Q
S
V
Y
RSGHSSPLSLGSIKPNIG
H
P
L
C
A
E
G
I
A
S
F
I
K
V
V
L
M
L
K
ERRFVPFLSG
E
K
E
M
A
H
F
D
Q
Q
KAN
I
T
F
S
R
A
L
E
K
WTDSQP
T
A
A
I
N
C
F
ADGGT
N
A
H
V
I
V
E
AWEKD
E
K
HAIKRSPIS
P
P
Q
L
K
K
R
MLSPGEPKLEAETSK
M
T
A
A
N
I
W
D
T
Y
EVEV
8
PsiBlast_PDB
78.81
30%
-117
- C1 -
4ZXI
5
?
A:
[19-1048]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
S
S
E
Q
L
G
I
W
Y
I
Q
R
L
E
P
T
C
S
A
Y
N
M
V
V
A
F
D
V
K
V
N
Q
S
L
G
N
-
K
P
I
E
-
I
L
E
A
V
M
H
D
Y
P
L
L
R
V
S
-
M
P
A
N
D
Q
G
I
E
Q
L
I
W
D
R
V
Y
P
-
N
I
I
F
S
D
A
R
H
I
E
----
A
S
D
L
T
Q
L
V
E
Q
-----
D
T
K
Q
P
F
D
L
T
Q
P
P
L
W
R
I
H
C
Y
E
C
G
Q
N
H
Y
V
I
A
F
V
I
H
H
A
L
M
D
F
W
S
I
G
L
L
L
R
D
V
S
K
R
F
G
L
V
A
E
S
----
D
A
V
N
G
I
E
F
V
Q
Y
A
D
K
Q
Q
S
S
V
I
-
D
D
T
D
E
S
L
I
F
W
K
N
A
L
K
------
H
A
P
H
V
H
S
I
P
L
D
YPRPAV
Q
Q
H
K
G
S
S
L
V
F
R
--
V
S
E
S
V
S
S
G
L
V
N
L
---
A
K
D
Y
E
I
T
L
F
G
L
V
L
S
G
F
Y
V
L
L
H
K
L
S
N
E
N
N
L
V
I
A
T
P
V
A
G
R
L
E
--
R
--
S
L
R
N
A
L
G
Q
F
V
N
T
I
A
I
H
M
D
I
D
A
D
Q
T
L
R
Q
F
T
Q
Q
V
Q
E
Q
L
R
Q
S
L
K
H
Q
K
I
A
F
S
R
V
V
E
A
V
S
P
K
R
D
G
S
I
N
P
-
L
A
Q
I
G
M
F
W
E
R
L
-
G
G
M
D
E
F
K
E
L
L
LPIQTP
A
T
L
-----
V
G
Q
D
--
L
T
L
G
S
F
-
P
V
R
Q
Q
E
G
Q
L
D
I
T
L
E
M
G
G
E
-
Y
Q
G
E
L
V
G
V
L
K
Y
N
T
D
L
F
S
A
Q
S
A
E
N
M
V
Q
L
L
Q
A
V
L
S
E
M
V
A
H
P
E
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K
I
V
E
L
D
I
A
P
D
Y
K
D
G
I
Q
F
E
A
L
R
G
K
A
T
D
Y
A
Q
--
H
D
L
F
A
M
I
L
K
Q
I
D
E
R
G
D
N
H
A
L
T
S
---
H
T
V
S
Y
R
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L
G
Q
H
I
A
G
I
A
E
Y
L
R
A
H
G
I
T
Q
G
D
R
V
G
L
M
L
D
R
T
A
L
L
P
A
A
I
L
G
I
W
A
A
G
A
A
Y
V
P
L
D
P
N
F
P
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E
R
L
Q
N
I
I
E
D
A
E
P
K
V
I
L
T
Q
T
E
L
---
M
D
---
G
L
N
---
V
--
S
V
P
R
L
---------
D
I
N
Q
A
G
V
V
A
L
E
Q
V
R
E
T
L
A
F
G
----------
D
I
A
Y
V
M
Y
T
S
----
K
P
K
G
V
R
I
G
H
P
S
I
I
N
F
L
L
S
M
N
D
R
L
---
Q
V
T
T
E
T
Q
L
L
A
I
T
T
Y
A
F
D
I
S
I
L
E
L
L
I
P
L
M
Y
G
G
V
V
H
V
C
P
R
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V
S
Q
D
G
I
Q
L
V
D
Y
L
N
A
K
S
I
N
V
L
Q
A
T
P
A
T
W
K
M
L
L
-
D
S
E
W
S
-
G
N
A
G
L
T
-----
A
L
--
C
G
G
E
--
A
L
-
D
T
I
L
A
E
K
L
L
G
K
--
V
G
--
C
L
W
N
V
Y
G
P
T
E
T
T
V
----
W
S
---
S
A
A
R
I
T
------
D
--
A
K
Y
I
D
-
L
G
E
P
L
A
-----
N
T
Q
L
Y
V
L
D
E
Q
-
Q
R
L
V
P
P
G
V
M
G
E
L
W
I
G
G
D
G
L
A
V
D
Y
W
Q
R
P
E
L
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A
Q
F
R
T
L
P
S
L
-
P
N
A
G
R
L
Y
R
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V
C
L
R
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D
G
R
L
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H
G
R
L
D
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K
I
R
G
F
R
I
E
L
G
E
I
E
N
V
L
K
Q
I
D
G
I
T
D
A
V
V
L
V
K
T
T
G
D
-----
N
D
Q
K
--
L
V
A
Y
V
T
G
-
Q
E
----
L
D
I
A
G
L
K
K
N
L
Q
I
H
L
P
A
Y
M
V
P
S
A
F
I
R
L
D
E
F
P
M
T
A
N
K
K
L
D
R
K
A
F
P
E
P
I
F
--
E
Q
S
N
D
Y
V
A
P
R
D
P
-
I
E
I
E
L
C
T
T
F
E
Q
I
L
S
V
K
R
V
G
I
H
D
D
F
F
E
L
G
G
H
S
L
L
A
V
K
L
V
N
H
L
K
K
A
F
G
T
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L
S
V
A
L
L
A
Q
Y
S
T
V
E
R
L
G
E
I
I
R
E
N
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
78.35
30%
-117
- C1 -
4ZXH
3
?
A:
[19-1048]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
S
S
E
Q
L
G
I
W
Y
I
Q
R
L
E
P
T
C
S
A
Y
N
M
V
V
A
F
D
V
K
V
N
Q
S
L
G
N
-
K
P
I
E
-
I
L
E
A
V
M
H
D
Y
P
L
L
R
V
S
-
M
P
A
N
D
Q
G
I
E
Q
L
I
W
D
R
V
Y
P
-
N
I
I
F
S
D
A
R
H
I
E
----
A
S
D
L
T
Q
L
V
E
Q
-----
D
T
K
Q
P
F
D
L
T
Q
P
P
L
W
R
I
H
C
Y
E
C
G
Q
N
H
Y
V
I
A
F
V
I
H
H
A
L
M
D
F
W
S
I
G
L
L
L
R
D
V
S
K
R
F
G
L
V
A
E
S
----
D
A
V
N
G
I
E
F
V
Q
Y
A
D
K
Q
Q
S
S
V
I
-
D
D
T
D
E
S
L
I
F
W
K
N
A
L
K
------
H
A
P
H
V
H
S
I
P
L
D
YPRPAV
Q
Q
H
K
G
S
S
L
V
F
R
--
V
S
E
S
V
S
S
G
L
V
N
L
---
A
K
D
Y
E
I
T
L
F
G
L
V
L
S
G
F
Y
V
L
L
H
K
L
S
N
E
N
N
L
V
I
A
T
P
V
A
G
R
L
E
--
R
--
S
L
R
N
A
L
G
Q
F
V
N
T
I
A
I
H
M
D
I
D
A
D
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V
V
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A
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P
-
L
A
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M
F
W
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R
L
-
G
G
M
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K
E
L
L
LPIQTP
A
T
L
-----
V
G
Q
D
--
L
T
L
G
S
F
-
P
V
R
Q
Q
E
G
Q
L
D
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L
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M
G
G
E
-
Y
Q
G
E
L
V
G
V
L
K
Y
N
T
D
L
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S
A
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S
A
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N
M
V
Q
L
L
Q
A
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L
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M
V
A
H
P
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L
D
I
A
P
D
Y
K
D
G
I
Q
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A
L
R
G
K
A
T
D
Y
A
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--
H
D
L
F
A
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I
L
K
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G
D
N
H
A
L
T
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---
H
T
V
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Y
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L
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Q
H
I
A
G
I
A
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Y
L
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A
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V
G
L
M
L
D
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A
L
L
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A
A
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W
A
A
G
A
A
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V
P
L
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L
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N
I
I
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D
A
E
P
K
V
I
L
T
Q
T
E
L
---
M
D
---
G
L
N
---
V
--
S
V
P
R
L
---------
D
I
N
Q
A
G
V
V
A
L
E
Q
V
R
E
T
L
A
F
G
----------
D
I
A
Y
V
M
Y
T
S
----
K
P
K
G
V
R
I
G
H
P
S
I
I
N
F
L
L
S
M
N
D
R
L
---
Q
V
T
T
E
T
Q
L
L
A
I
T
T
Y
A
F
D
I
S
I
L
E
L
L
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L
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G
G
V
V
H
V
C
P
R
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V
S
Q
D
G
I
Q
L
V
D
Y
L
N
A
K
S
I
N
V
L
Q
A
T
P
A
T
W
K
M
L
L
-
D
S
E
W
S
-
G
N
A
G
L
T
-----
A
L
--
C
G
G
E
--
A
L
-
D
T
I
L
A
E
K
L
L
G
K
--
V
G
--
C
L
W
N
V
Y
G
P
T
E
T
T
V
----
W
S
---
S
A
A
R
I
T
------
D
--
A
K
Y
I
D
-
L
G
E
P
L
A
-----
N
T
Q
L
Y
V
L
D
E
Q
-
Q
R
L
V
P
P
G
V
M
G
E
L
W
I
G
G
D
G
L
A
V
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Y
W
Q
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A
Q
F
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L
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S
L
-
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A
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L
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D
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V
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L
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H
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K
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F
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L
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N
V
L
K
Q
I
D
G
I
T
D
A
V
V
L
V
K
T
T
G
D
-----
N
D
Q
K
--
L
V
A
Y
V
T
G
-
Q
E
----
L
D
I
A
G
L
K
K
N
L
Q
I
H
L
P
A
Y
M
V
P
S
A
F
I
R
L
D
E
F
P
M
T
A
N
K
K
L
D
R
K
A
F
P
E
P
I
F
--
E
Q
S
N
D
Y
V
A
P
R
D
P
-
I
E
I
E
L
C
T
T
F
E
Q
I
L
S
V
K
R
V
G
I
H
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D
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F
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L
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S
L
L
A
V
K
L
V
N
H
L
K
K
A
F
G
T
E
L
S
V
A
L
L
A
Q
Y
S
T
V
E
R
L
G
E
I
I
R
E
N
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
63
HHSearch
77.20
100%
-74
- C2 -
4NA1
2
PKSJ_BACSU
A:
[22-633]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
E
P
V
A
I
V
G
I
S
G
R
F
P
G
A
M
D
I
D
E
F
W
K
N
L
E
E
G
K
D
S
I
T
E
V
P
K
D
R
W
D
W
R
E
H
Y
G
N
P
D
T
D
V
N
K
T
D
I
K
W
G
G
F
I
D
G
V
A
E
F
D
P
L
F
F
G
I
S
P
R
E
A
D
Y
V
D
P
Q
Q
R
L
L
M
T
Y
V
W
K
A
L
E
D
A
G
C
S
P
Q
S
L
S
----------
G
T
G
T
G
I
F
I
G
T
G
N
T
G
Y
K
D
L
F
H
R
A
N
L
P
I
E
G
H
A
A
T
G
H
M
I
P
S
V
G
P
N
R
M
S
Y
F
L
N
I
H
G
P
S
E
P
V
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T
A
C
S
S
S
L
V
A
I
H
R
A
V
T
A
M
Q
N
G
D
C
E
M
A
I
A
G
G
V
N
T
I
L
T
E
E
A
H
I
S
Y
S
K
A
G
M
L
S
T
D
G
R
C
K
T
F
S
A
D
A
N
G
Y
V
R
G
E
G
V
G
M
V
M
L
K
K
L
E
D
A
E
R
D
G
N
H
I
Y
G
V
I
R
G
T
A
E
N
H
G
G
R
A
N
T
L
T
S
P
N
P
K
A
Q
A
D
L
L
V
R
A
Y
R
Q
A
D
I
D
P
S
T
V
T
Y
I
E
A
H
G
T
G
T
E
L
G
D
P
I
E
I
N
G
L
K
A
A
F
K
E
L
S
N
M
------
D
V
P
D
H
R
C
G
I
G
S
V
K
S
N
I
G
H
L
E
L
A
A
G
I
S
G
L
I
K
V
L
L
Q
M
K
H
K
T
L
V
K
S
L
H
C
E
T
L
N
P
Y
L
Q
L
T
D
S
P
F
Y
I
V
Q
E
K
Q
E
W
K
S
V
T
D
R
D
G
N
E
L
P
R
R
A
G
I
S
S
F
G
I
G
G
V
N
A
H
I
V
I
E
E
Y
M
P
---------
E
Q
P
N
V
I
V
L
S
A
K
N
K
S
R
L
I
D
R
A
S
Q
L
L
E
V
I
R
N
K
K
Y
T
D
Q
D
L
H
R
I
A
Y
T
L
Q
V
G
R
E
E
M
D
E
R
L
A
C
V
A
G
T
M
Q
E
L
E
E
K
L
Q
A
F
V
D
G
K
E
E
T
D
E
F
F
R
G
Q
S
H
R
N
K
E
T
Q
T
I
F
T
A
D
E
D
M
A
L
A
L
D
A
W
I
R
K
R
K
Y
A
K
L
A
D
L
W
V
K
G
V
S
I
Q
W
N
T
L
Y
G
E
-
T
K
P
R
L
I
S
L
P
S
Y
P
F
A
K
D
H
Y
W
V
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
76.73
99%
-74
- C2 -
4NA1
2
PKSJ_BACSU
A:
[22-633]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
E
P
V
A
I
V
G
I
S
G
R
F
P
G
A
M
D
I
D
E
F
W
K
N
L
E
E
G
K
D
S
I
T
E
V
P
K
D
R
W
D
W
R
E
H
Y
G
N
P
D
T
D
V
N
K
T
D
I
K
W
G
G
F
I
D
G
V
A
E
F
D
P
L
F
F
G
I
S
P
R
E
A
D
Y
V
D
P
Q
Q
R
L
L
M
T
Y
V
W
K
A
L
E
D
A
G
C
S
P
Q
S
L
S
----------
G
T
G
T
G
I
F
I
G
T
G
N
T
G
Y
K
D
L
F
H
R
A
N
L
P
I
E
G
H
A
A
T
G
H
M
I
P
S
V
G
P
N
R
M
S
Y
F
L
N
I
H
G
P
S
E
P
V
E
T
A
C
S
S
S
L
V
A
I
H
R
A
V
T
A
M
Q
N
G
D
C
E
M
A
I
A
G
G
V
N
T
I
L
T
E
E
A
H
I
S
Y
S
K
A
G
M
L
S
T
D
G
R
C
K
T
F
S
A
D
A
N
G
Y
V
R
G
E
G
V
G
M
V
M
L
K
K
L
E
D
A
E
R
D
G
N
H
I
Y
G
V
I
R
G
T
A
E
N
H
G
G
R
A
N
T
L
T
S
P
N
P
K
A
Q
A
D
L
L
V
R
A
Y
R
Q
A
D
I
D
P
S
T
V
T
Y
I
E
A
H
G
T
G
T
E
L
G
D
P
I
E
I
N
G
L
K
A
A
F
K
E
L
S
N
M
------
D
V
P
D
H
R
C
G
I
G
S
V
K
S
N
I
G
H
L
E
L
A
A
G
I
S
G
L
I
K
V
L
L
Q
M
K
H
K
T
L
V
K
S
L
H
C
E
T
L
N
P
Y
L
Q
L
T
D
S
P
F
Y
I
V
Q
E
K
Q
E
W
K
S
V
T
D
R
D
G
N
E
L
P
R
R
A
G
I
S
S
F
G
I
G
G
V
N
A
H
I
V
I
E
E
Y
M
P
---------
E
Q
P
N
V
I
V
L
S
A
K
N
K
S
R
L
I
D
R
A
S
Q
L
L
E
V
I
R
N
K
K
Y
T
D
Q
D
L
H
R
I
A
Y
T
L
Q
V
G
R
E
E
M
D
E
R
L
A
C
V
A
G
T
M
Q
E
L
E
E
K
L
Q
A
F
V
D
G
K
E
E
T
D
E
F
F
R
G
Q
S
H
R
N
K
E
T
Q
T
I
F
T
A
D
E
D
M
A
L
A
L
D
A
W
I
R
K
R
K
Y
A
K
L
A
D
L
W
V
K
G
V
S
I
Q
W
N
T
L
Y
G
E
-
T
K
P
R
L
I
S
L
P
S
Y
P
F
A
K
D
H
Y
W
V
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
76.72
99%
-70
- C2 -
4NA2
-
PKSJ_BACSU
A:
[3-615]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
E
P
V
A
I
V
G
I
S
G
R
F
P
G
A
M
D
I
D
E
F
W
K
N
L
E
E
G
K
D
S
I
T
E
V
P
K
D
R
W
D
W
R
E
H
Y
G
N
P
D
T
D
V
N
K
T
D
I
K
W
G
G
F
I
D
G
V
A
E
F
D
P
L
F
F
G
I
S
P
R
E
A
D
Y
V
D
P
Q
Q
R
L
L
M
T
Y
V
W
K
A
L
E
D
A
G
C
S
P
Q
S
L
S
----------
G
T
G
T
G
I
F
I
G
T
G
N
T
G
Y
K
D
L
F
H
R
A
N
L
P
I
E
G
H
A
A
T
G
H
M
I
P
S
V
G
P
N
R
M
S
Y
F
L
N
I
H
G
P
S
E
P
V
E
T
A
-
S
S
S
L
V
A
I
H
R
A
V
T
A
M
Q
N
G
D
C
E
M
A
I
A
G
G
V
N
T
I
L
T
E
E
A
H
I
S
Y
S
K
A
G
M
L
S
T
D
G
R
C
K
T
F
S
A
D
A
N
G
Y
V
R
G
E
G
V
G
M
V
M
L
K
K
L
E
D
A
E
R
D
G
N
H
I
Y
G
V
I
R
G
T
A
E
N
H
G
G
R
A
N
T
L
T
S
P
N
P
K
A
Q
A
D
L
L
V
R
A
Y
R
Q
A
D
I
D
P
S
T
V
T
Y
I
E
A
H
G
T
G
T
E
L
G
D
P
I
E
I
N
G
L
K
A
A
F
K
E
L
S
N
M
R
----
P
D
V
P
D
H
R
C
G
I
G
S
V
K
S
N
I
G
H
L
E
L
A
A
G
I
S
G
L
I
K
V
L
L
Q
M
K
H
K
T
L
V
K
S
L
H
C
E
T
L
N
P
Y
L
Q
L
T
D
S
P
F
Y
I
V
Q
E
K
Q
E
W
K
S
V
T
D
R
D
G
N
E
L
P
R
R
A
G
I
S
S
F
G
I
G
G
V
N
A
H
I
V
I
E
E
Y
M
P
----------
Q
P
N
V
I
V
L
S
A
K
N
K
S
R
L
I
D
R
A
S
Q
L
L
E
V
I
R
N
K
K
Y
T
D
Q
D
L
H
R
I
A
Y
T
L
Q
V
G
R
E
E
M
D
E
R
L
A
C
V
A
G
T
M
Q
E
L
E
E
K
L
Q
A
F
V
D
G
K
-----
F
F
R
G
Q
S
H
R
N
K
E
T
Q
T
I
F
T
A
D
E
D
M
A
L
A
L
D
A
W
I
R
K
R
K
Y
A
K
L
A
D
L
W
V
K
G
V
S
I
Q
W
N
T
L
Y
G
E
-
T
K
P
R
L
I
S
L
P
S
Y
P
F
A
K
D
H
Y
W
V
P
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
76.46
99%
-74
- C2 -
4NA1
4
B:
[22-634]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
E
P
V
A
I
V
G
I
S
G
R
F
P
G
A
M
D
I
D
E
F
W
K
N
L
E
E
G
K
D
S
I
T
E
V
P
K
D
R
W
D
W
R
E
H
Y
G
N
P
D
T
D
V
N
K
T
D
I
K
W
G
G
F
I
D
G
V
A
E
F
D
P
L
F
F
G
I
S
P
R
E
A
D
Y
V
D
P
Q
Q
R
L
L
M
T
Y
V
W
K
A
L
E
D
A
G
C
S
P
Q
S
L
S
----------
G
T
G
T
G
I
F
I
G
T
G
N
T
G
Y
K
D
L
F
H
R
A
N
L
P
I
E
G
H
A
A
T
G
H
M
I
P
S
V
G
P
N
R
M
S
Y
F
L
N
I
H
G
P
S
E
P
V
E
T
A
C
S
S
S
L
V
A
I
H
R
A
V
T
A
M
Q
N
G
D
C
E
M
A
I
A
G
G
V
N
T
I
L
T
E
E
A
H
I
S
Y
S
K
A
G
M
L
S
T
D
G
R
C
K
T
F
S
A
D
A
N
G
Y
V
R
G
E
G
V
G
M
V
M
L
K
K
L
E
D
A
E
R
D
G
N
H
I
Y
G
V
I
R
G
T
A
E
N
H
G
G
R
A
N
T
L
T
S
P
N
P
K
A
Q
A
D
L
L
V
R
A
Y
R
Q
A
D
I
D
P
S
T
V
T
Y
I
E
A
H
G
T
G
T
E
L
G
D
P
I
E
I
N
G
L
K
A
A
F
K
E
L
S
N
M
R
--------
D
H
R
C
G
I
G
S
V
K
S
N
I
G
H
L
E
L
A
A
G
I
S
G
L
I
K
V
L
L
Q
M
K
H
K
T
L
V
K
S
L
H
C
E
T
L
N
P
Y
L
Q
L
T
D
S
P
F
Y
I
V
Q
E
K
Q
E
W
K
S
V
T
D
R
D
G
N
E
L
P
R
R
A
G
I
S
S
F
G
I
G
G
V
N
A
H
I
V
I
E
E
Y
M
P
----------
Q
P
N
V
I
V
L
S
A
K
N
K
S
R
L
I
D
R
A
S
Q
L
L
E
V
I
R
N
K
K
Y
T
D
Q
D
L
H
R
I
A
Y
T
L
Q
V
G
R
E
E
M
D
E
R
L
A
C
V
A
G
T
M
Q
E
L
E
E
K
L
Q
A
F
V
D
G
K
E
----
F
F
R
G
Q
S
H
R
N
K
E
T
Q
T
I
F
T
A
D
E
D
M
A
L
A
L
D
A
W
I
R
K
R
K
Y
A
K
L
A
D
L
W
V
K
G
V
S
I
Q
W
N
T
L
Y
G
E
-
T
K
P
R
L
I
S
L
P
S
Y
P
F
A
K
D
H
Y
W
V
P
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
72.97
31%
-98
- C1 -
2VSQ
2
SRFAC_BACSU
A:
[15-1056]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
P
M
Q
E
G
M
L
F
H
A
I
L
N
P
G
Q
S
F
Y
L
E
Q
I
T
M
--
K
V
K
G
S
L
N
I
-
K
C
L
E
E
S
M
N
V
I
M
D
R
Y
D
V
F
R
T
V
F
I
H
E
K
V
-
K
R
P
V
Q
V
V
L
K
K
R
Q
F
H
I
E
E
I
D
L
T
H
L
T
----
G
S
E
Q
T
A
K
I
N
E
Y
K
E
Q
D
K
I
R
G
F
D
L
T
R
D
I
P
M
-
R
A
A
I
F
K
K
A
E
E
S
F
E
W
V
W
S
Y
H
H
I
I
L
D
G
W
C
F
G
I
V
V
Q
D
L
F
K
V
Y
N
A
L
-
R
E
Q
K
P
Y
S
L
P
P
V
K
P
Y
K
D
Y
I
K
W
----
L
E
K
Q
D
K
Q
A
S
L
R
Y
W
R
E
Y
L
E
G
------
F
E
G
Q
T
T
F
A
E
Q
------
R
K
K
Q
K
D
G
Y
E
P
K
E
L
L
F
S
P
S
E
A
E
T
K
A
F
T
E
L
A
K
S
Q
H
T
T
L
S
T
A
L
Q
A
V
W
S
V
L
I
S
R
Y
Q
Q
S
G
D
L
A
F
G
T
V
V
S
G
R
P
A
--
E
IK
G
V
E
H
M
V
G
L
F
I
N
V
V
P
R
R
V
K
L
S
E
G
I
T
F
N
G
L
L
K
R
L
Q
E
Q
S
L
Q
S
E
P
H
Q
Y
V
P
L
Y
D
I
-------
Q
S
Q
A
D
Q
P
K
L
I
D
H
I
I
V
F
E
N
Y
P
L
Q
D
A
K
N
E
E
---------
S
S
-----
E
N
G
F
--
D
M
V
D
V
---
H
V
F
E
K
S
N
Y
D
L
N
L
-
M
A
-
S
-
P
G
D
E
M
L
I
K
L
A
Y
N
E
N
V
F
D
E
A
F
I
L
R
L
K
S
Q
L
L
T
A
I
Q
Q
L
I
Q
N
P
D
Q
P
V
S
T
I
N
L
V
D
D
R
E
R
E
F
L
L
T
G
L
N
P
P
A
Q
A
H
E
T
--
K
P
L
T
Y
W
F
K
E
A
V
N
A
N
P
D
A
P
A
L
T
Y
-
S
G
Q
T
L
S
Y
R
E
L
D
E
E
A
N
R
I
A
R
R
L
Q
K
H
G
A
G
K
G
S
V
V
A
L
Y
T
K
R
S
L
E
L
V
I
G
I
L
G
V
L
K
A
G
A
A
Y
L
P
V
D
P
K
L
P
E
D
R
I
S
Y
M
L
A
D
S
A
A
A
C
L
L
T
H
Q
E
M
KEQ
A
A
---
E
L
P
Y
T
G
T
--
T
L
F
I
D
---------
D
Q
T
R
F
E
--
E
Q
A
S
D
P
A
T
---
A
I
D
P
------
N
D
P
A
Y
I
M
Y
T
S
G
T
T
G
K
P
K
G
N
I
T
T
H
A
N
I
Q
G
-
L
V
K
H
V
D
Y
M
---
A
F
S
D
Q
D
T
F
L
S
V
S
N
Y
A
F
D
A
F
T
F
D
F
Y
A
S
M
L
N
A
A
R
L
I
I
A
D
E
H
T
L
L
D
T
E
R
L
T
D
L
I
L
Q
E
N
V
N
V
M
F
A
T
T
A
L
F
N
L
L
T
-
D
A
G
E
D
-
W
M
K
G
L
R
C
----
I
L
--
F
G
G
E
RA
S
V
-
P
H
V
R
K
A
L
R
I
M
G
--
P
G
--
K
L
I
N
C
Y
G
P
T
E
G
T
V
----
F
A
T
A
H
V
V
H
D
L
P
--
D
---
S
--
I
S
S
L
P
-
I
G
K
P
I
S
-----
N
A
S
V
Y
I
L
N
E
Q
-
S
Q
L
Q
P
F
G
A
V
G
E
L
C
I
S
G
M
G
V
S
K
G
Y
V
N
R
A
D
L
T
K
E
K
F
I
E
N
P
F
K
-
P
G
E
-
T
L
Y
R
T
G
D
L
A
R
W
L
P
D
G
T
I
E
Y
A
G
R
I
D
D
Q
V
K
I
R
G
H
R
I
E
L
E
E
I
E
K
Q
L
Q
E
Y
P
G
V
K
D
A
V
V
V
A
D
R
--
H
ESGD
A
S
-----
I
N
A
Y
L
V
N
-
R
---
T
Q
L
S
A
E
D
V
K
A
H
L
K
K
Q
L
P
A
Y
M
V
P
Q
T
F
T
F
L
D
E
L
P
L
T
T
N
G
K
V
N
K
R
L
L
P
K
P
D
--
Q
D
Q
L
A
E
E
W
I
G
P
R
N
E
M
E
E
T
I
A
Q
I
W
S
E
V
L
G
R
K
Q
I
G
I
H
D
D
F
F
A
L
G
G
H
A
L
K
A
M
T
A
A
S
R
I
K
K
E
L
G
I
D
L
P
V
K
L
L
F
E
A
P
T
I
A
G
I
S
A
Y
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
62
HHSearch
68.40
30%
-114
- C1 -
4ZXH
3
?
A:
[13-1047]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
L
S
R
H
A
I
S
S
E
Q
L
G
I
W
Y
I
Q
R
L
E
P
T
C
S
A
Y
N
M
V
V
A
F
--
D
V
K
V
N
Q
S
L
G
N
K
P
I
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I
L
E
A
V
M
H
D
Y
P
L
L
R
V
S
-
M
P
A
N
D
-
Q
G
I
E
Q
L
I
W
D
R
V
Y
P
N
I
I
F
S
D
A
R
H
I
E
----
A
S
D
L
T
Q
L
V
E
Q
-----
D
T
K
Q
P
F
D
L
T
Q
P
P
L
W
R
I
H
C
Y
E
C
G
Q
N
H
Y
V
I
A
F
V
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H
H
A
L
M
D
F
W
S
I
G
L
L
L
R
D
V
S
K
R
F
G
L
V
A
E
S
D
A
----
V
N
G
I
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F
V
Q
Y
A
D
K
Q
Q
S
S
V
I
-
D
D
T
D
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S
L
I
F
W
K
N
A
L
K
H
A
P
H
V
H
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I
P
L
D
Y
P
R
P
A
V
------
Q
Q
H
K
G
S
S
L
V
F
R
--
V
S
E
S
V
S
S
G
L
V
N
L
---
A
K
D
Y
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T
L
F
G
L
V
L
S
G
F
Y
V
L
L
H
K
L
S
N
E
N
N
L
V
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A
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V
A
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--
R
--
S
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P
-
L
A
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M
F
W
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R
L
-
G
G
M
D
E
F
K
E
L
L
-------
L
P
IQTP
A
T
L
V
G
QD
L
T
L
G
S
F
-
P
V
R
Q
Q
E
G
Q
L
D
I
T
L
E
M
G
-
G
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Y
Q
G
E
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V
G
V
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K
Y
N
T
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L
F
S
A
Q
S
A
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N
M
V
Q
L
L
Q
A
V
L
S
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V
A
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D
Y
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D
G
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A
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--
H
D
L
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A
M
I
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G
D
N
H
A
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---
H
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Q
H
I
A
G
I
A
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Y
L
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A
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K
V
I
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T
Q
T
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---
M
D
---
G
L
N
V
S
-----
V
P
R
L
---------
D
I
N
Q
A
G
----
V
V
A
L
E
Q
V
R
E
T
L
A
F
------
G
D
I
A
Y
V
M
Y
T
S
----
K
P
K
G
V
R
I
G
H
P
S
I
I
N
F
L
L
S
M
N
D
R
L
---
Q
V
T
T
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T
Q
L
L
A
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T
Y
A
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S
I
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L
L
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G
G
V
V
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P
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Y
L
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A
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S
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N
V
L
Q
A
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P
A
T
W
K
M
L
L
-
D
S
E
W
S
-
G
N
A
G
L
T
-----
A
L
--
C
G
G
E
--
A
L
-
D
T
I
L
A
E
K
L
L
G
K
--
V
G
--
C
L
W
N
V
Y
G
P
T
E
T
T
V
----
W
S
---
S
A
A
R
I
T
------
D
--
A
K
Y
I
D
-
L
G
E
P
L
A
-----
N
T
Q
L
Y
V
L
D
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Q
-
Q
R
L
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P
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V
M
G
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G
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G
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S
L
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A
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-
R
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V
L
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Q
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D
G
I
T
D
A
V
V
L
V
K
T
--
T
GDN
D
Q
K
-----
L
V
A
Y
V
T
G
-
Q
E
----
L
D
I
A
G
L
K
K
N
L
Q
I
H
L
P
A
Y
M
V
P
S
A
F
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R
L
D
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F
P
M
T
A
N
K
K
L
D
R
K
A
F
P
E
P
I
F
E
Q
S
N
--
D
Y
V
A
P
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D
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-
I
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I
E
L
C
T
T
F
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Q
I
L
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V
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V
G
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F
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L
G
G
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S
L
L
A
V
K
L
V
N
H
L
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K
A
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L
S
V
A
L
L
A
Q
Y
S
T
V
E
R
L
G
E
I
I
R
E
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
65.98
39%
-110
- C1 -
4R0M
1
?
B:
[18-561]
-----------------------------
T
L
S
E
V
L
-
E
T
A
T
K
-
H
N
N
H
G
I
T
Y
I
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D
A
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Y
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Y
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A
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G
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K
V
I
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A
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A
C
F
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G
G
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V
P
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V
A
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Y
D
L
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S
A
V
K
K
L
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V
W
K
I
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P
L
I
L
S
D
S
E
L
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K
L
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Y
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H
L
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G
W
Q
V
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V
N
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L
R
K
A
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S
K
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Q
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P
I
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D
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Q
D
A
A
L
L
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G
S
T
G
M
P
K
G
V
I
L
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H
H
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I
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A
G
T
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V
M
N
H
F
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Q
Q
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T
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W
M
P
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A
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F
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A
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D
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A
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D
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M
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L
V
L
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H
Q
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S
I
S
W
S
P
N
F
A
F
S
L
I
N
Q
Q
A
E
E
L
K
H
V
S
Y
N
L
S
S
M
K
F
L
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N
A
G
E
Q
V
S
V
K
T
I
R
L
F
L
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I
L
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H
Q
L
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A
I
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P
A
F
G
M
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C
S
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W
S
A
G
L
S
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N
E
L
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F
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P
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A
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N
N
P
L
P
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R
E
I
G
R
L
Q
I
Q
G
N
S
V
T
K
G
Y
Y
N
N
N
E
L
N
Q
E
V
F
Q
E
-
G
W
F
T
T
G
D
L
G
Y
L
S
K
G
E
L
F
I
T
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R
E
K
Q
E
I
I
I
N
G
V
N
Y
F
A
H
E
L
E
T
T
I
E
E
L
E
G
V
K
V
S
Y
T
A
A
F
A
V
F
D
Q
S
R
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D
L
L
I
I
T
F
S
P
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S
E
-
Q
F
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Q
G
I
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V
V
R
K
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H
V
T
Q
K
F
G
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A
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A
Y
V
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L
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N
L
V
P
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T
S
I
G
K
V
Q
K
S
K
L
K
K
D
F
E
Q
G
L
F
S
------
S
R
I
Q
E
I
D
Q
Y
L
A
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
72
HHSearch
64.84
45%
-76
* C2 *
4TKT
6
?
A:
[6-617]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
M
A
I
A
I
V
G
M
A
G
R
Y
P
G
A
P
D
L
D
T
F
W
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N
L
L
A
G
R
D
S
I
T
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P
A
G
R
W
D
H
S
R
Y
Y
D
A
R
R
G
V
P
G
R
T
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K
W
G
G
F
L
D
G
I
D
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F
D
P
L
F
F
G
I
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P
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A
A
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T
M
D
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R
L
F
L
Q
C
A
H
T
T
L
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D
A
G
Y
S
R
G
A
L
R
A
A
A
R
A
R
V
AED
A
G
D
I
G
V
F
A
G
A
M
Y
S
E
Y
Q
L
Y
G
A
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V
R
G
E
P
V
V
V
P
G
--
S
L
A
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A
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A
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A
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C
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A
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A
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D
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G
V
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A
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H
G
G
H
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P
N
P
L
A
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A
A
V
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A
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R
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D
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C
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A
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G
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L
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D
P
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I
A
G
L
N
A
A
F
A
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F
T
D
---------
A
R
N
F
C
A
I
G
S
A
K
S
N
I
G
H
L
E
S
A
A
G
I
A
G
L
A
K
L
L
L
Q
M
R
H
G
T
L
V
P
S
L
H
A
E
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V
N
P
D
I
D
F
A
D
S
P
F
V
L
Q
R
E
A
A
P
W
P
R
T
G
-----
T
R
P
R
L
G
G
L
S
S
F
G
A
G
G
S
N
A
H
V
V
V
E
D
Y
V
E
-------
H
R
G
E
T
V
V
V
V
L
S
A
F
D
E
E
R
L
R
E
S
A
G
R
L
R
D
A
L
R
K
E
R
W
S
S
A
D
L
P
D
I
A
Y
T
L
Q
V
G
R
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A
M
T
A
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A
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A
V
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T
L
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A
L
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D
A
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D
A
C
A
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S
G
L
P
A
G
A
Y
F
N
P
G
---------------
F
Q
E
T
A
V
R
W
A
R
R
G
K
P
A
P
L
A
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A
W
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A
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P
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A
L
P
G
Y
P
F
A
R
E
R
Y
W
Y
T
D
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
64.12
39%
-120
- C1 -
4D4G
4
?
A:
[31-514]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
I
H
Q
L
F
E
T
Q
V
E
R
T
P
E
A
V
A
V
L
S
-
E
Q
G
Q
L
T
Y
E
E
L
N
T
K
A
N
Q
L
A
H
Y
L
R
T
L
G
V
K
S
E
T
L
V
G
V
C
V
D
R
S
L
E
M
V
I
G
L
L
A
I
L
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A
G
G
A
Y
V
P
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D
P
T
Y
P
R
E
R
L
T
Y
M
V
Q
D
A
Q
I
S
V
L
V
T
Q
T
Q
W
---
S
N
---
L
I
S
D
Y
Q
G
--
Q
V
I
C
L
---------
D
S
Q
W
A
K
I
A
S
Y
S
Q
E
N
--
L
V
N
T
V
N
P
------
E
N
L
A
Y
V
I
Y
T
S
G
S
T
G
K
P
K
G
V
M
I
E
H
Q
S
L
V
N
F
T
K
L
A
I
A
Q
Y
---
Q
I
T
T
S
D
R
T
L
Q
F
V
S
I
S
F
D
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A
A
E
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T
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A
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L
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A
Y
W
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L
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-
N
E
L
V
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-
S
K
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A
L
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DSLR
L
V
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--
I
G
G
E
--
R
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L
V
R
M
W
F
K
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V
--
G
N
FP
E
L
I
N
V
Y
G
P
T
E
G
T
I
----
A
V
---
S
L
C
R
L
S
QL
T
---
E
--
S
Q
R
N
R
-
T
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P
I
G
K
S
LGE
N
I
S
V
Y
V
L
D
E
T
-
L
K
T
V
P
P
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G
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I
G
G
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A
L
A
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L
N
R
P
E
L
T
A
Q
K
F
I
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D
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F
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-
P
S
E
-
R
L
Y
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G
D
L
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Y
L
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L
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L
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K
I
N
G
F
R
V
E
L
G
E
I
E
T
V
L
L
Q
H
H
Q
V
A
Q
A
V
V
I
D
R
---------
R
-----
L
V
A
Y
L
V
P
-
H
S
T
E
E
N
L
T
V
T
-
L
Q
Q
F
L
K
N
K
L
P
S
Y
M
I
P
A
T
F
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
63.95
99%
-71
- C2 -
4NA3
2
PKSJ_BACSU
A:
[22-633]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
E
P
V
A
I
V
G
I
S
G
R
F
P
G
A
M
D
I
D
E
F
W
K
N
L
E
E
G
K
D
S
I
T
E
V
P
K
D
R
W
D
W
R
E
H
Y
G
N
P
D
T
D
V
N
K
T
D
I
K
W
G
G
F
I
D
G
V
A
E
F
D
P
L
F
F
G
I
S
P
R
E
A
D
Y
V
D
P
Q
Q
R
L
L
M
T
Y
V
W
K
A
L
E
D
A
G
C
S
P
Q
S
L
S
----------
G
T
G
T
G
I
F
I
G
T
G
N
T
G
Y
K
D
L
F
H
R
A
N
L
P
I
E
G
H
A
A
T
G
H
M
I
P
S
V
G
P
N
R
M
S
Y
F
L
N
I
H
G
P
S
E
P
V
E
T
A
G
S
S
S
L
V
A
I
H
R
A
V
T
A
M
Q
N
G
D
C
E
M
A
I
A
G
G
V
N
T
I
L
T
E
E
A
H
I
S
Y
S
K
A
G
M
L
S
T
D
G
R
C
K
T
F
S
A
D
A
N
G
Y
V
R
G
E
G
V
G
M
V
M
L
K
K
L
E
D
A
E
R
D
G
N
H
I
Y
G
V
I
R
G
T
A
E
N
H
G
G
R
A
N
T
L
T
S
P
N
P
K
A
Q
A
D
L
L
V
R
A
Y
R
Q
A
D
I
D
P
S
T
V
T
Y
I
E
A
H
G
T
G
T
E
L
G
D
P
I
E
I
N
G
L
K
A
A
F
K
E
L
S
N
M
------
D
V
P
D
H
R
C
G
I
G
S
V
K
S
N
I
G
H
L
E
L
A
A
G
I
S
G
L
I
K
V
L
L
Q
M
K
H
K
T
L
V
K
S
L
H
C
E
T
L
N
P
Y
L
Q
L
T
D
S
P
F
Y
I
V
Q
E
K
Q
E
W
K
S
V
T
D
R
D
G
N
E
L
P
R
R
A
G
I
S
S
F
G
I
G
G
V
N
A
H
I
V
I
E
E
Y
M
P
---------
E
Q
P
N
V
I
V
L
S
A
K
N
K
S
R
L
I
D
R
A
S
Q
L
L
E
V
I
R
N
K
K
Y
T
D
Q
D
L
H
R
I
A
Y
T
L
Q
V
G
R
E
E
M
D
E
R
L
A
C
V
A
G
T
M
Q
E
L
E
E
K
L
Q
A
F
V
D
G
K
E
E
T
D
E
F
F
R
G
Q
S
H
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N
K
E
T
Q
T
I
F
T
A
D
E
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M
A
L
A
L
D
A
W
I
R
K
R
K
Y
A
K
L
A
D
L
W
V
K
G
V
S
I
Q
W
N
T
L
Y
G
E
-
T
K
P
R
L
I
S
L
P
S
Y
P
F
A
K
D
H
Y
W
V
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
78
Fugue
63.80
42%
-114
- C1 -
1AMU
4
GRSA_ANEMI
A:
[17-530]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
T
H
E
E
E
Q
Y
L
F
A
V
N
N
T
K
A
E
Y
P
-RD
K
T
I
H
Q
L
F
E
E
Q
V
S
K
R
P
N
N
V
A
I
V
C
E-
N
E
Q
L
T
Y
H
E
L
N
V
K
A
N
Q
L
A
R
I
F
I
E
K
G
I
G
K
D
T
L
V
G
I
M
M
E
K
S
I
D
L
F
I
G
I
L
A
V
L
K
A
G
G
A
Y
V
P
I
D
I
E
Y
P
K
E
R
I
Q
Y
I
L
D
D
S
Q
A
R
M
L
L
T
Q
K
H
L
---
V
H
---
L
I
H
N
I
----
Q
F
N
--
G
Q
V
E
I
FEED------
T
I
K
I
R
-----
E
G
T
N
L
H
-VPSKST-
D
L
A
Y
V
I
Y
T
-----
S
P
K
G
T
M
L
E
H
K
G
I
S
N
L
K
V
F
F
E
N
--SLN-
V
T
E
K
D
R
I
G
Q
F
A
S
I
S
F
D
A
S
V
W
E
M
F
M
A
L
L
T
G
A
S
L
Y
I
I
L
K
D
T
I
N
D
F
V
K
F
E
Q
Y
I
N
Q
K
E
I
T
V
I
T
L
P
P
T
Y
V
V
H
L
-D
P
E
R
I
---
L
S
I
Q
T
-----
L
I
--
T
A
G
S
--
A
T
-
S
P
S
L
V
N
K
W
K
E
K
V-----
T
Y
I
N
A
Y
G
P
T
E
T
T
I
----
C
A
---
T
T
W
V
A
T
--
K
---
E
T
I
G
H
S
V
P
-
I
G
A
P
I
Q
-----
N
T
Q
I
Y
I
V
D
E
-N
L
Q
L
K
S
V
G
E
A
G
E
L
C
I
G
G
E
G
L
A
R
G
Y
W
K
R
P
E
L
T
S
Q
K
F
V
D
N
P
F
V
-
P
G
E
-
K
L
Y
K
T
G
D
Q
A
R
W
L
S
D
G
N
I
E
Y
L
G
R
I
D
N
Q
V
K
I
R
G
H
R
V
E
L
E
E
V
E
S
I
L
L
K
H
M
Y
I
S
E
T
A
V
S
V
H
K
--
D
HQE
Q
P
Y
-----
L
C
A
Y
F
V
S
-
E
---
K
H
I
P
L
E
Q
L
R
Q
F
S
S
E
E
L
P
T
Y
M
I
P
S
Y
F
I
Q
L
D
K
M
P
L
T
S
N
G
K
I
D
R
K
Q
L
P
E
P
D
L
T
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
63.74
39%
-122
- C1 -
4D57
5
?
A:
[31-516]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
I
H
Q
L
F
E
T
Q
V
E
R
T
P
E
A
V
A
V
L
S
-
E
Q
G
Q
L
T
Y
E
E
L
N
T
K
A
N
Q
L
A
H
Y
L
R
T
L
G
V
K
S
E
T
L
V
G
V
C
V
D
R
S
L
E
M
V
I
G
L
L
A
I
L
K
A
G
G
A
Y
V
P
L
D
P
T
Y
P
R
E
R
L
T
Y
M
V
Q
D
A
Q
I
S
V
L
V
T
Q
T
Q
W
---
S
N
---
L
I
S
D
Y
Q
G
--
Q
V
I
C
L
---------
D
S
Q
W
A
K
I
A
S
Y
S
Q
E
N
--
L
V
N
T
V
N
P
------
E
N
L
A
Y
V
I
Y
T
S
G
S
T
G
K
P
K
G
V
M
I
E
H
Q
S
L
V
N
F
T
K
L
A
I
A
Q
Y
---
Q
I
T
T
S
D
R
T
L
Q
F
V
S
I
S
F
D
V
A
A
E
E
I
Y
V
T
L
C
S
G
A
T
L
I
L
R
T
E
E
M
I
S
S
I
P
S
F
V
Q
K
S
Q
D
W
Q
I
T
V
W
S
L
P
T
A
Y
W
H
L
L
V
-
N
E
L
V
K
-
S
K
I
A
L
P
DSLR
L
V
I
--
I
G
G
E
--
R
V
Q
P
E
L
V
R
M
W
F
K
N
V
--
G
N
FP
E
L
I
N
V
Y
G
P
T
E
G
T
I
----
A
V
---
S
L
C
R
L
S
QL
T
---
E
--
S
Q
R
N
R
-
T
E
I
P
I
G
K
S
LGE
N
I
S
V
Y
V
L
D
E
T
-
L
K
T
V
P
P
E
T
P
G
E
I
Y
I
G
G
T
A
L
A
R
G
Y
L
N
R
P
E
L
T
A
Q
K
F
I
Q
D
P
F
S
-
P
S
E
-
R
L
Y
K
T
G
D
L
G
R
Y
L
A
D
G
N
L
E
Y
L
G
R
V
D
H
Q
V
K
I
N
G
F
R
V
E
L
G
E
I
E
T
V
L
L
Q
H
H
Q
V
A
Q
A
V
V
I
D
R
---------
R
-----
L
V
A
Y
L
V
P
-
H
S
T
E
E
N
L
T
V
T
-
L
Q
Q
F
L
K
N
K
L
P
S
Y
M
I
P
A
T
F
V
V
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
63.31
39%
-123
- C1 -
4D56
5
?
A:
[31-516]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
I
H
Q
L
F
E
T
Q
V
E
R
T
P
E
A
V
A
V
L
S
-
E
Q
G
Q
L
T
Y
E
E
L
N
T
K
A
N
Q
L
A
H
Y
L
R
T
L
G
V
K
S
E
T
L
V
G
V
C
V
D
R
S
L
E
M
V
I
G
L
L
A
I
L
K
A
G
G
A
Y
V
P
L
D
P
T
Y
P
R
E
R
L
T
Y
M
V
Q
D
A
Q
I
S
V
L
V
T
Q
T
Q
W
---
S
N
---
L
I
S
D
Y
Q
G
--
Q
V
I
C
L
---------
D
S
Q
W
A
K
I
A
S
Y
S
Q
E
N
--
L
V
N
T
V
N
P
------
E
N
L
A
Y
V
I
Y
T
S
G
S
T
G
K
P
K
G
V
M
I
E
H
Q
S
L
V
N
F
T
K
L
A
I
A
Q
Y
---
Q
I
T
T
S
D
R
T
L
Q
F
V
S
I
S
F
D
V
A
A
E
E
I
Y
V
T
L
C
S
G
A
T
L
I
L
R
T
E
E
M
I
S
S
I
P
S
F
V
Q
K
S
Q
D
W
Q
I
T
V
W
S
L
P
T
A
Y
W
H
L
L
V
-
N
E
L
V
K
-
S
K
I
A
L
P
DSLR
L
V
I
--
I
G
G
E
--
R
V
Q
P
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L
V
R
M
W
F
K
N
V
--
G
N
FP
E
L
I
N
V
Y
G
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T
E
G
T
I
----
A
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---
S
L
C
R
L
S
QL
T
---
E
--
S
Q
R
N
R
-
T
E
I
P
I
G
KSLGE
N
I
S
V
Y
V
L
D
E
T
-
L
K
T
V
P
P
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T
P
G
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I
Y
I
G
G
T
A
L
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R
G
Y
L
N
R
P
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L
T
A
Q
K
F
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Q
D
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F
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-
P
S
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-
R
L
Y
K
T
G
D
L
G
R
Y
L
A
D
G
N
L
E
Y
L
G
R
V
D
H
Q
V
K
I
N
G
F
R
V
E
L
G
E
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E
T
V
L
L
Q
H
H
Q
V
A
Q
A
V
V
I
D
R
---------
R
-----
L
V
A
Y
L
V
P
-
H
S
T
E
E
N
L
T
V
T
-
L
Q
Q
F
L
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N
K
L
P
S
Y
M
I
P
A
T
F
V
V
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
68
HHSearch
63.29
29%
-98
- C1 -
2VSQ
2
SRFAC_BACSU
A:
[9-1059]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
Q
D
M
Y
Y
L
S
P
M
Q
E
G
M
L
F
H
A
I
L
N
P
G
Q
S
F
Y
L
E
Q
I
T
M
--
K
V
K
G
S
L
N
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-
K
C
L
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M
N
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D
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Y
D
V
F
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V
-
F
I
H
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K
V
K
R
P
V
Q
V
V
L
K
K
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Q
F
H
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E
I
D
L
T
H
L
T
G
S
E
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T
A
K
I
N
E
Y
K
E
Q
-----
D
K
I
R
G
F
D
L
T
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D
I
P
M
R
A
A
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F
K
K
A
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V
W
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Y
H
H
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I
L
D
G
W
C
F
G
I
V
V
Q
D
L
F
K
V
Y
N
A
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K
P
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S
L
-
P
P
V
K
P
Y
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D
Y
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K
W
L
E
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Q
----
D
K
Q
A
S
L
R
Y
W
R
E
Y
L
E
G
F
E
G
Q
T
T
F
A
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K
K
Q
-
K
------
D
G
Y
E
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L
L
F
S
--
P
S
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A
E
T
K
A
F
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L
---
A
K
S
Q
H
T
T
L
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T
A
L
Q
A
V
W
S
V
L
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S
R
Y
Q
Q
S
G
D
L
A
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G
T
V
V
S
G
R
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A
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K
--
G
V
E
H
M
V
G
L
F
I
N
V
V
P
R
R
V
K
L
S
E
G
I
T
F
N
G
L
L
K
R
L
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S
L
Q
S
E
P
H
Q
Y
V
P
L
Y
D
I
Q
S
Q
A
D
Q
------
P
K
-
L
I
D
H
I
I
V
F
E
N
Y
-
P
L
Q
D
A
K
N
E
E
S
----------------
S
E
--
N
G
F
D
M
V
D
V
H
V
F
E
K
S
N
Y
D
L
N
L
M
A
S
---
P
G
D
E
M
L
I
K
L
A
Y
N
E
N
V
F
D
E
A
F
I
L
R
L
K
S
Q
L
L
T
A
I
Q
Q
L
I
Q
N
P
D
Q
P
V
S
T
I
N
L
V
D
D
R
E
R
E
F
L
L
T
G
L
N
P
P
A
Q
A
H
E
T
--
K
P
L
T
Y
W
F
K
E
A
V
N
A
N
P
D
A
P
A
L
T
Y
-
S
G
Q
T
L
S
Y
R
E
L
D
E
E
A
N
R
I
A
R
R
L
Q
K
H
G
A
G
K
G
S
V
V
A
L
Y
T
K
R
S
L
E
L
V
I
G
I
L
G
V
L
K
A
G
A
A
Y
L
P
V
D
P
K
L
P
E
D
R
I
S
Y
M
L
A
D
S
A
A
A
C
L
L
T
H
Q
E
M
---
K
E
---
Q
A
A
E
L
P
Y
T
G
T
T
L
F
I
---------
D
D
-
Q
T
R
F
---
E
E
Q
A
S
D
P
A
T
A
I
D
P
------
N
D
P
A
Y
I
M
Y
T
S
G
T
T
G
K
P
K
G
N
I
T
T
H
A
N
I
Q
G
L
V
K
H
V
-
D
Y
M
---
A
F
S
D
Q
D
T
F
L
S
V
S
N
Y
A
F
D
A
F
T
F
D
F
Y
A
S
M
L
N
A
A
R
L
I
I
A
D
E
H
T
L
L
D
T
E
R
L
T
D
L
I
L
Q
E
N
V
N
V
M
F
A
T
T
A
L
F
N
L
L
T
-
D
A
G
E
D
W
M
K
G
L
R
C
-----
I
L
--
F
G
G
E
--
R
A
-
S
V
P
H
V
R
K
A
L
R
I
M
G
P
G
--
K
L
I
N
C
Y
G
P
T
E
G
T
V
----
F
A
---
T
A
H
V
V
H
--
D
LPD
S
--
I
S
S
L
P
-
I
G
K
P
I
S
-----
N
A
S
V
Y
I
L
N
E
Q
-
S
Q
L
Q
P
F
G
A
V
G
E
L
C
I
S
G
M
G
V
S
K
G
Y
V
N
R
A
D
L
T
K
E
K
F
I
E
N
P
F
K
-
P
G
E
-
T
L
Y
R
T
G
D
L
A
R
W
L
P
D
G
T
I
E
Y
A
G
R
I
D
D
Q
V
K
I
R
G
H
R
I
E
L
E
E
I
E
K
Q
L
Q
E
Y
P
G
V
K
D
A
V
V
V
A
D
R
--
H
ESGD
A
S
-----
I
N
A
Y
L
V
N
-
R
T
---
Q
L
S
A
E
D
V
K
A
H
L
K
K
Q
L
P
A
Y
M
V
P
Q
T
F
T
F
L
D
E
L
P
L
T
T
N
G
K
V
N
K
R
L
L
P
K
P
D
Q
D
Q
L
A
-
E
E
W
I
G
P
R
N
E
-
M
E
E
T
I
A
Q
I
W
S
E
V
L
G
R
K
Q
I
G
I
H
D
D
F
F
A
L
G
G
H
A
L
K
A
M
T
A
A
S
R
I
K
K
E
L
G
I
D
L
P
V
K
L
L
F
E
A
P
T
I
A
G
I
S
A
Y
L
K
N
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
63.03
99%
-68
- C2 -
4NA3
4
B:
[22-634]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
E
P
V
A
I
V
G
I
S
G
R
F
P
G
A
M
D
I
D
E
F
W
K
N
L
E
E
G
K
D
S
I
T
E
V
P
K
D
R
W
D
W
R
E
H
Y
G
N
P
D
T
D
V
N
K
T
D
I
K
W
G
G
F
I
D
G
V
A
E
F
D
P
L
F
F
G
I
S
P
R
E
A
D
Y
V
D
P
Q
Q
R
L
L
M
T
Y
V
W
K
A
L
E
D
A
G
C
S
P
Q
S
L
S
----------
G
T
G
T
G
I
F
I
G
T
G
N
T
G
Y
K
D
L
F
H
R
A
N
L
P
I
E
G
H
A
A
T
G
H
M
I
P
S
V
G
P
N
R
M
S
Y
F
L
N
I
H
G
P
S
E
P
V
E
T
A
G
S
S
S
L
V
A
I
H
R
A
V
T
A
M
Q
N
G
D
C
E
M
A
I
A
G
G
V
N
T
I
L
T
E
E
A
H
I
S
Y
S
K
A
G
M
L
S
T
D
G
R
C
K
T
F
S
A
D
A
N
G
Y
V
R
G
E
G
V
G
M
V
M
L
K
K
L
E
D
A
E
R
D
G
N
H
I
Y
G
V
I
R
G
T
A
E
N
H
G
G
R
A
N
T
L
T
S
P
N
P
K
A
Q
A
D
L
L
V
R
A
Y
R
Q
A
D
I
D
P
S
T
V
T
Y
I
E
A
H
G
T
G
T
E
L
G
D
P
I
E
I
N
G
L
K
A
A
F
K
E
L
S
N
M
R
--------
D
H
R
C
G
I
G
S
V
K
S
N
I
G
H
L
E
L
A
A
G
I
S
G
L
I
K
V
L
L
Q
M
K
H
K
T
L
V
K
S
L
H
C
E
T
L
N
P
Y
L
Q
L
T
D
S
P
F
Y
I
V
Q
E
K
Q
E
W
K
S
V
T
D
R
D
G
N
E
L
P
R
R
A
G
I
S
S
F
G
I
G
G
V
N
A
H
I
V
I
E
E
Y
M
P
----------
Q
P
N
V
I
V
L
S
A
K
N
K
S
R
L
I
D
R
A
S
Q
L
L
E
V
I
R
N
K
K
Y
T
D
Q
D
L
H
R
I
A
Y
T
L
Q
V
G
R
E
E
M
D
E
R
L
A
C
V
A
G
T
M
Q
E
L
E
E
K
L
Q
A
F
V
D
G
K
E
----
F
F
R
G
Q
S
H
R
N
K
E
T
Q
T
I
F
T
A
D
E
D
M
A
L
A
L
D
A
W
I
R
K
R
K
Y
A
K
L
A
D
L
W
V
K
G
V
S
I
Q
W
N
T
L
Y
G
E
-
T
K
P
R
L
I
S
L
P
S
Y
P
F
A
K
D
H
Y
W
V
P
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
63.01
39%
-122
- C1 -
4D4I
4
?
A:
[31-515]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
I
H
Q
L
F
E
T
Q
V
E
R
T
P
E
A
V
A
V
L
S
-
E
Q
G
Q
L
T
Y
E
E
L
N
T
K
A
N
Q
L
A
H
Y
L
R
T
L
G
V
K
S
E
T
L
V
G
V
C
V
D
R
S
L
E
M
V
I
G
L
L
A
I
L
K
A
G
G
A
Y
V
P
L
D
P
T
Y
P
R
E
R
L
T
Y
M
V
Q
D
A
Q
I
S
V
L
V
T
Q
T
Q
W
---
S
N
---
L
I
S
D
Y
Q
G
--
Q
V
I
C
L
---------
D
S
Q
W
A
K
I
A
S
Y
S
Q
E
N
--
L
V
N
T
V
N
P
------
E
N
L
A
Y
V
I
Y
T
S
G
S
T
G
K
P
K
G
V
M
I
E
H
Q
S
L
V
N
F
T
K
L
A
I
A
Q
Y
---
Q
I
T
T
S
D
R
T
L
Q
F
V
S
I
S
F
D
V
A
A
E
E
I
Y
V
T
L
C
S
G
A
T
L
I
L
R
T
E
E
M
I
S
S
I
P
S
F
V
Q
K
S
Q
D
W
Q
I
T
V
W
S
L
P
T
A
Y
W
H
L
L
V
-
N
E
L
V
K
-
S
K
I
A
L
P
DSLR
L
V
I
--
I
G
G
E
--
R
V
Q
P
E
L
V
R
M
W
F
K
N
V
--
G
N
FP
E
L
I
N
V
Y
G
P
T
E
G
T
I
----
A
V
---
S
L
C
R
L
S
QL
T
---
E
--
S
Q
R
N
R
-
T
E
I
P
I
G
K
S
LGE
N
I
S
V
Y
V
L
D
E
T
-
L
K
T
V
P
P
E
T
P
G
E
I
Y
I
G
G
T
A
L
A
R
G
Y
L
N
R
P
E
L
T
A
Q
K
F
I
Q
D
P
F
S
-
P
S
E
-
R
L
Y
K
T
G
D
L
G
R
Y
L
A
D
G
N
L
E
Y
L
G
R
V
D
H
Q
V
K
I
N
G
F
R
V
E
L
G
E
I
E
T
V
L
L
Q
H
H
Q
V
A
Q
A
V
V
I
D
R
---------
R
-----
L
V
A
Y
L
V
P
-
H
S
T
E
E
N
L
T
V
T
-
L
Q
Q
F
L
K
N
K
L
P
S
Y
M
I
P
A
T
F
V
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
PsiBlast_CBE
62.39
41%
-104
- C1 -
1AMU
4
GRSA_ANEMI
A:
[20-530]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
E
Q
Y
L
F
A
V
N
N
T
K
A
E
Y
P
R
D-
K
T
I
H
Q
L
F
E
E
Q
V
S
K
R
P
N
N
V
A
I
V
C
-
E
N
E
Q
L
T
Y
H
E
L
N
V
K
A
N
Q
L
A
R
I
F
I
E
K
G
I
G
K
D
T
L
V
G
I
M
M
E
K
S
I
D
L
F
I
G
I
L
A
V
L
K
A
G
G
A
Y
V
P
I
D
I
E
Y
P
K
E
R
I
Q
Y
I
L
D
D
S
Q
A
R
M
L
L
T
Q
K
H
L
---
V
H
L
I
H
N
I
Q
F
N
G
---
Q
V
E
I
F
---------
E
E
D
T
I
K
I
R
E
-
G
T
N
L
H
V
P
S
K
S
T
---------
D
L
A
Y
V
I
Y
T
S
-----
P
K
G
T
M
L
E
H
K
G
I
S
N
L
K
V
F
F
E
N
S
L
---
N
V
T
E
K
D
R
I
G
Q
F
A
S
I
S
F
D
A
S
V
W
E
M
F
M
A
L
L
T
G
A
S
L
Y
I
I
L
K
D
T
I
N
D
F
V
K
F
E
Q
Y
I
N
Q
K
E
I
T
V
I
T
L
P
P
T
---
Y
V
V
-
H
L
D
P
E
-
R
I
L
S
I
Q
-----
T
L
I
T
A
G
S
A
--
T
S
-
P
S
L
V
N
K
W
--
K
E
--
K
V
--
T
Y
I
N
A
Y
G
P
T
E
T
T
I
CA
T
T
W
V
---
A
T
K
E
T
----------
I
G
H
S
V
P
I
G
A
P
I
Q
-----
N
T
Q
I
Y
I
V
D
E
N
-
L
Q
L
K
S
V
G
E
A
G
E
L
C
I
G
G
E
G
L
A
R
G
Y
W
K
R
P
E
L
T
S
Q
K
F
V
D
N
P
F
V
-
P
G
E
-
K
L
Y
K
T
G
D
Q
A
R
W
L
S
D
G
N
I
E
Y
L
G
R
I
D
N
Q
V
K
I
R
G
H
R
V
E
L
E
E
V
E
S
I
L
L
K
H
M
Y
I
S
E
T
A
V
S
V
H
K
--
D
-----
H
QE
Q
P
Y
L
C
A
Y
F
V
S
E
K
H
----
I
P
L
E
Q
L
R
Q
F
S
S
E
E
L
P
T
Y
M
I
P
S
Y
F
I
Q
L
D
K
M
P
L
T
S
N
G
K
I
D
R
K
Q
L
P
E
P
D
L
T
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
58
HHSearch
62.11
38%
-77
- C2 -
4NA1
2
PKSJ_BACSU
A:
[22-633]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
E
P
V
A
I
V
G
I
S
G
R
F
P
G
A
M
D
I
D
E
F
W
K
N
L
E
E
G
K
D
S
I
T
E
V
P
K
D
R
W
D
W
R
E
H
Y
GN
P
D
T
D
V
N
K
T
D
I
K
W
G
G
F
I
D
G
V
A
E
F
D
P
L
F
F
G
I
S
P
R
E
A
D
Y
V
D
P
Q
Q
R
L
L
M
T
Y
V
W
K
A
L
E
D
A
G
C
S
P
Q
S
L
SG
T
G
T
G
I
F
I
G
T
G
N
T
G
Y
K
D
L
F
H
R
A
N
L
P
----
I
E
G
H
A
A
T
G
H
M
I
P
S
V
G
P
N
R
M
S
Y
F
L
N
I
H
G
P
S
E
P
V
E
T
A
C
S
S
S
L
V
A
I
H
R
A
V
T
A
M
Q
N
G
D
C
E
M
A
I
A
G
G
V
N
T
I
L
T
E
E
A
H
I
S
Y
S
K
A
G
M
L
S
T
D
G
R
C
K
T
F
S
A
D
A
N
G
Y
V
R
G
E
G
V
G
M
V
M
L
K
K
L
E
D
A
E
R
D
G
N
H
I
Y
G
V
I
R
G
T
A
E
N
H
G
G
R
A
-
N
T
L
T
S
P
N
P
K
A
Q
A
D
L
L
V
R
A
Y
R
Q
A
D
I
D
P
S
T
V
T
Y
I
E
A
H
G
T
G
T
E
L
G
D
P
I
E
I
N
G
L
K
A
A
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