@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu21970: (2016-07-04 )
MKLRPHLKIEAKGTGSVSFFSEDWLTAQQARTFARELGRFPYMKELEFEDEKGGSWTLKELEKLTEELAQEPDDITVYFDGSFDKESELAGLGIVIYYSLGGTRHRLRKNKSFRLKTNNEAEYAALYEAIREVRELGASRNSITIKGDSLVVLNQLDGSWPCYDPSHNEWLDKIEALLESLKLTPTYETIQRKDNQEADGLAKKILSHQFVESHTKLDRNGDDDIG
Atome Classification :
(20 SA)
--------------------------------------.........10........20...---------.....30........40........-50........60.......------------.70....---....80.....--..----.90.....-----...100..--..-...110.-.-..-..------------------------------.120.......130.....--..--140.--......150......--------.--------160--------.---.--..---.-------..170.......-180.......190----.----......200.......----210.......220....-
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------------------MKLRP
H
L
K
I
E
AKGTG
S
V
S
FFSEDW---------
L
T
A
Q
Q
A
R
T
F
A
R
E
LGRFP
Y
M
K
E
LEFE-DEKGGSW
T
L
K
E
L
E
K
L
T
E
E
L
------------AQEPD
D
I
---
T
V
Y
FDGSFDKE--SE----LA
G
L
G
I
V
I
-----
Y
Y
SLGG
T
R
--
H
R
-LRKNK
S
F
-
R
-
L
K-TN------------------------------NE
A
E
Y
A
A
L
Y
E
A
I
R
E
V
R
E
LG--AS--R
N
S
I
--
T
I
KG
D
S
L
V
V
L
NQLDG--------S--------WPC--------Y---D--P
S
---
H
-------
N
E
W
L
D
K
I
E
A
L
L
E
-SLKLTP
T
Y
E
T
I
Q
R----K----DNQ
E
A
D
G
L
A
K
K
I
L
S
H
Q
----
F
V
E
S
HTKLDRNGDDDIG-
21
HHSearch
80.33
28%
-47
- C4 -
4E19
3
RNH_HALSA
A:
[67-198]
-----------------------------------------------------------------------------------------------------------------------------------
G
G
R
V
---
H
A
Y
F
D
G
A
S
R
G
N
--
P
G
----
P
A
A
V
G
W
V
L
-----
V
S
G
D
G
G
I
V
--
A
---
E
G
G
D
T
I
-
G
-
R
A
-
T
N
------------------------------
N
Q
A
E
Y
D
A
L
I
A
A
L
E
A
A
A
D
F
G
--
F
----
D
D
I
--
E
L
R
G
D
S
Q
L
V
E
K
Q
L
T
G
--------
A
--------
W
D
T
--------
N
---
D
--
P
D
---
L
-------
R
R
K
R
V
R
A
R
E
L
L
T
-
G
F
D
-
D
W
S
I
T
H
V
P
R
----
A
----
T
N
E
R
A
D
A
L
A
N
E
A
L
D
D
-----------------------
6
PsiBlast_PDB
78.40
29%
-55
- C4 -
4NYN
2
RNH_HALSA
A:
[70-196]
--------------------------------------------------------------------------------------------------------------------------------------
V
---
H
A
Y
F
D
G
A
S
R
G
N
--
P
G
----
P
A
A
V
G
W
V
L
-----
V
S
G
D
G
G
I
V
-----
A
E
G
G
D
T
I
-
G
-
R
A
-
T
N
------------------------------
N
Q
A
E
Y
D
A
L
I
A
A
L
E
A
A
A
D
F
G
--
F
----
D
D
I
--
E
L
R
G
D
S
Q
L
V
E
K
Q
L
T
G
--------
A
--------
W
D
T
--------
N
---
D
--
P
D
---
L
-------
R
R
K
R
V
R
A
R
E
L
L
T
-
G
F
D
-
D
W
S
I
T
H
V
P
R
----
A
----
T
N
E
R
A
D
A
L
A
N
E
A
L
-------------------------
5
PsiBlast_PDB
78.32
29%
-56
- C4 -
4E19
2
RNH_HALSA
A:
[70-196]
--------------------------------------------------------------------------------------------------------------------------------------
V
---
H
A
Y
F
D
G
A
S
R
G
N
--
P
G
----
P
A
A
V
G
W
V
L
-----
V
S
G
D
G
G
I
V
-----
A
E
G
G
D
T
I
-
G
-
R
A
-
T
N
------------------------------
N
Q
A
E
Y
D
A
L
I
A
A
L
E
A
A
A
D
F
G
--
F
----
D
D
I
--
E
L
R
G
D
S
Q
L
V
E
K
Q
L
T
G
--------
A
--------
W
D
T
--------
N
---
D
--
P
D
---
L
-------
R
R
K
R
V
R
A
R
E
L
L
T
-
G
F
D
-
D
W
S
I
T
H
V
P
R
----
A
----
T
N
E
R
A
D
A
L
A
N
E
A
L
-------------------------
41
Fugue
77.31
28%
-17
- C4 -
2EHG
-
RNH_SULTO
A:
[1-149]
-------------------------------------------------------------------------------------------------------------------------------------
M
I
---
I
G
Y
F
D
G
L
C
E
P
K
--
N
P
G
G
--
I
A
T
F
G
F
V
I
-----
Y
L
D
N
R
K
I
E
--
G
Y
G
L
A
E
K
P
F
S
-
I
-
N
S
-
T
N
------------------------------
N
V
A
E
Y
S
G
L
I
C
L
M
E
T
M
L
R
L
G
--
I
S
----
S
P
--
I
I
K
G
D
S
Q
L
V
I
K
Q
M
N
G
--------
E
--------
Y
K
V
--------
K
---
A
--
K
R
---
I
-------
I
P
L
Y
E
K
A
I
E
L
K
K
-
K
L
N
A
--
T
L
I
W
V
P
R
----
E
----
E
N
K
E
A
D
R
L
S
R
V
A
Y
E
L
V
R
R
GK
L
R
D
I
G
C
I
I
L
T
--------
24
HHSearch
73.85
29%
-10
- C4 -
2EHG
-
RNH_SULTO
A:
[2-142]
--------------------------------------------------------------------------------------------------------------------------------------
I
---
I
G
Y
F
D
G
L
C
E
P
K
NP
G
G
----
I
A
T
F
G
F
V
I
-----
Y
L
D
N
R
K
I
E
--
G
Y
-
G
L
A
E
K
P
F
-
S
I
N
S
-
T
N
------------------------------
N
V
A
E
Y
S
G
L
I
C
L
M
E
T
M
L
R
L
G
--
I
----
S
S
P
--
I
I
K
G
D
S
Q
L
V
I
K
Q
M
N
G
--------
E
--------
Y
K
V
--------
K
---
A
--
K
R
---
I
-------
I
P
L
Y
E
K
A
I
E
L
K
K
-
K
L
--
N
A
T
L
I
W
V
P
R
----
E
----
E
N
K
E
A
D
R
L
S
R
V
A
Y
E
L
V
----
R
R
G
K
L
R
D
-----------
23
HHSearch
72.85
26%
26
- C4 -
3U3G
-
?
D:
[2-138]
------------------------------------------------------------------------------------------------------------------------------------
N
K
I
---
I
I
Y
T
D
G
G
A
R
G
N
--
P
G
----
P
A
G
I
G
V
V
I
-----
T
D
E
K
G
N
T
L
-----
H
E
S
S
A
Y
I
-
G
-
E
T
-
T
N
------------------------------
N
V
A
E
Y
E
A
L
I
R
A
L
E
D
L
Q
M
F
G
--
D
K
LV
D
M
E
V
--
E
V
R
M
D
S
E
L
I
V
R
Q
M
Q
G
--------
V
--------
Y
K
V
--------
K
---
E
--
P
T
---
L
-------
K
E
K
F
A
K
I
A
H
I
K
M
-
E
R
V
P
N
L
V
F
V
H
I
P
R
----
E
----
K
N
A
R
A
D
E
L
V
N
E
A
I
D
K
A
----------------------
22
HHSearch
71.56
27%
24
- C4 -
3HST
-
Y2228_MYCTU
B:
[3-135]
-------------------------------------------------------------------------------------------------------------------------------------
K
V
---
V
I
E
A
D
G
G
S
R
G
N
--
P
G
----
P
A
G
Y
G
A
V
V
-----
W
T
A
D
H
S
T
V
--
L
---
A
E
S
K
Q
A
I
G
-
R
A
-
T
N
------------------------------
N
V
A
E
Y
R
G
L
I
A
G
L
D
D
A
V
K
L
G
--
A
----
T
E
A
--
A
V
L
M
D
S
K
L
V
V
E
Q
M
S
G
--------
R
--------
W
K
V
--------
K
---
H
--
P
D
---
L
-------
L
K
L
Y
V
Q
A
Q
A
L
A
S
-
Q
F
R
-
R
I
N
Y
E
W
V
P
R
----
A
----
R
N
T
Y
A
D
R
L
A
N
D
A
M
D
A
A
----
A
-----------------
7
PsiBlast_PDB
70.96
28%
-72
- C4 -
3HST
-
Y2228_MYCTU
B:
[4-127]
--------------------------------------------------------------------------------------------------------------------------------------
V
---
V
I
E
A
D
G
G
S
R
G
N
--
P
G
----
P
A
G
Y
G
A
V
V
-----
W
T
A
D
H
S
T
V
--
L
A
-
E
S
K
Q
A
I
G
-
R
--
A
-
T
N
------------------------------
N
V
A
E
Y
R
G
L
I
A
G
L
D
D
A
V
K
L
G
--
A
T
--
E
A
A
V
--
L
M
--
D
S
K
L
V
V
E
Q
M
S
G
--------
R
--------
W
K
V
--------
K
---
H
--
P
D
---
L
-------
L
K
L
Y
V
Q
A
Q
A
L
A
S
-
Q
F
R
R
I
-
N
Y
E
W
V
P
R
----
A
----
R
N
T
Y
A
D
R
L
A
-----------------------------
4
PsiBlast_PDB
70.82
25%
12
- C4 -
4H8K
2
?
A:
[3-135]
-------------------------------------------------------------------------------------------------------------------------------------
K
I
---
I
I
Y
T
D
G
G
A
R
G
N
--
P
G
----
P
A
G
I
G
V
V
I
-----
T
D
E
K
G
N
T
L
--
H
E
---
S
S
A
Y
I
-
G
-
E
T
-
T
N
------------------------------
N
V
A
E
Y
E
A
L
I
R
A
L
E
D
L
Q
M
F
G
DK
L
V
--
D
M
E
V
--
E
V
R
M
N
S
E
L
I
V
R
Q
M
Q
G
--------
V
--------
Y
K
V
--------
K
---
E
--
P
T
---
L
-------
K
E
K
F
A
K
I
A
H
I
K
M
-
E
R
V
P
N
L
V
F
V
H
I
P
R
----
E
----
K
N
A
R
A
D
E
L
V
N
E
A
I
-------------------------
1
PsiBlast_PDB
70.75
26%
20
- C4 -
3U3G
-
?
D:
[2-135]
------------------------------------------------------------------------------------------------------------------------------------
N
K
I
---
I
I
Y
T
D
G
G
A
R
G
N
--
P
G
----
P
A
G
I
G
V
V
I
-----
T
D
E
K
G
N
T
L
--
H
E
---
S
S
A
Y
I
-
G
-
E
T
-
T
N
------------------------------
N
V
A
E
Y
E
A
L
I
R
A
L
E
D
L
Q
M
F
G
DK
L
V
--
D
M
E
V
--
E
V
R
M
D
S
E
L
I
V
R
Q
M
Q
G
--------
V
--------
Y
K
V
--------
K
---
E
--
P
T
---
L
-------
K
E
K
F
A
K
I
A
H
I
K
M
-
E
R
V
P
N
L
V
F
V
H
I
P
R
----
E
----
K
N
A
R
A
D
E
L
V
N
E
A
I
-------------------------
36
HHSearch
66.70
21%
-25
* C4 *
2E4L
-
RNH_SHEON
A:
[4-149]
-----------------------------------------------------------------------------------------------------------------------------------
L
K
L
I
---
H
I
F
T
D
G
S
C
L
G
N
--
P
G
----
P
G
G
Y
G
I
V
M
-----
N
Y
K
G
H
T
-------
K
E
M
S
D
G
F
-
S
-
L
T
-
T
N
------------------------------
N
R
M
E
L
L
A
P
I
V
A
L
E
A
L
K
E
P
--------
C
K
I
--
I
L
T
S
D
S
Q
Y
M
R
Q
G
I
M
T
W
I
H
G
W
K
K
K
G
--------
W
M
T
--------
S
---
N
--
R
T
PVK
N
-------
V
D
L
W
K
R
L
D
K
A
A
Q
--
L
-
H
Q
I
D
W
R
W
V
K
G
----
H
AGH
A
E
N
E
R
C
D
Q
L
A
R
A
A
A
E
A
N
----
P
T
Q
---------------
2
PsiBlast_PDB
66.60
32%
20
- C4 -
3ALY
-
RNH_SULTO
A:
[2-129]
--------------------------------------------------------------------------------------------------------------------------------------
I
---
I
G
Y
F
D
G
L
C
E
P
K
--
N
P
G
G
--
I
A
T
F
G
F
V
I
-----
Y
L
D
N
R
K
I
E
--
G
Y
-
G
L
A
E
K
P
F
-
S
-
I
N
S
T
N
------------------------------
N
V
A
E
Y
S
G
L
I
C
L
M
E
T
M
L
R
L
G
--
I
S
----
S
P
--
I
I
K
G
D
S
Q
L
V
I
K
Q
M
N
G
--------
E
-------------------
Y
---
K
--
V
K
---
A
-------
K
R
I
I
P
L
Y
E
K
A
I
E
L
K
K
K
L
N
A
T
L
I
W
V
P
R
----
E
----
E
N
K
E
A
D
R
L
S
R
----------------------------
3
PsiBlast_PDB
66.10
32%
19
- C4 -
2EHG
-
RNH_SULTO
A:
[2-129]
--------------------------------------------------------------------------------------------------------------------------------------
I
---
I
G
Y
F
D
G
L
C
E
P
K
--
N
P
G
G
--
I
A
T
F
G
F
V
I
-----
Y
L
D
N
R
K
I
E
--
G
Y
-
G
L
A
E
K
P
F
-
S
-
I
N
S
T
N
------------------------------
N
V
A
E
Y
S
G
L
I
C
L
M
E
T
M
L
R
L
G
--
I
S
----
S
P
--
I
I
K
G
D
S
Q
L
V
I
K
Q
M
N
G
--------
E
-------------------
Y
---
K
--
V
K
---
A
-------
K
R
I
I
P
L
Y
E
K
A
I
E
L
K
K
K
L
N
A
T
L
I
W
V
P
R
----
E
----
E
N
K
E
A
D
R
L
S
R
----------------------------
33
HHSearch
64.46
19%
-44
- C4 -
1JL1
-
RNH_ECOLI
A:
[3-146]
------------------------------------------------------------------------------------------------------------------------------------
K
Q
V
---
E
I
F
T
A
G
S
A
L
G
N
--
P
G
----
P
G
G
Y
G
A
I
L
-----
R
Y
R
G
R
E
K
-------
T
F
S
A
G
Y
-
T
-
R
T
-
T
N
------------------------------
N
R
M
E
L
M
A
A
I
V
A
L
E
A
L
K
E
H
--------
A
E
V
--
I
L
S
T
D
S
Q
Y
V
R
Q
G
I
T
Q
--------
W
I
H
N
W
K
K
R
G
W
K
T
--------
A
DKK
P
--
V
K
---
N
-------
V
D
L
W
Q
R
L
D
A
A
L
G
-
Q
H
--
Q
I
K
W
E
W
V
K
G
----
H
AGH
P
E
N
E
R
A
D
E
L
A
R
A
A
A
M
N
P
----
T
L
----------------
31
HHSearch
64.45
20%
-13
- C4 -
3H08
1
?
A:
[3-145]
------------------------------------------------------------------------------------------------------------------------------------
K
T
I
---
T
I
Y
T
D
G
A
A
S
G
N
--
P
G
----
K
G
G
W
G
A
L
L
-----
M
Y
G
S
S
R
----
K
---
E
I
S
G
Y
D
-
P
-
A
T
-
T
N
------------------------------
N
R
M
E
L
M
A
A
I
K
G
L
E
A
L
K
E
P
--------
A
R
V
--
Q
L
Y
S
D
S
A
Y
L
V
N
A
M
N
E
--------
G
--------
W
L
K
R
W
V
K
N
GWK
K
---
P
--
V
E
---
N
-------
I
D
L
W
Q
E
I
L
K
L
T
T
-
L
--
H
R
V
T
F
H
K
V
K
G
-----SDN
P
Y
N
S
R
A
D
E
L
A
R
L
A
I
K
E
N
----------------------
48
Fugue
63.22
20%
73
- C3 -
4TXD
1
?
A:
[21-369]
KRD
V
L
A
E
L
GLGDLRPY
L
R
S
I
GDKDRIFPKA
H
R
I
E
V
V
F
L
V
R
A
A
N
Y
L
L
L
R
T
E
G
A
G
T
I
N
M
T
T
L
E
Y
SG
G
A
M
E
V
P
V
I
Q
P
Q
K
L
M
A
V
T
R
R
Q
-
M
L
Q
L
L
R
E
Y
R
D
S
L
D
E
V
S
K
R
W
L
V
Q
E
V
I
G
K
A
K
D
L
GFKKVSEE
W
N
C
T
I
Q
G
M
D
G
F
C
P
H
C
T
I
F
G
A
A
L
T
E
Q
HN
E
K
----
F
G
G
L
S
I
G
I
K
T
R
V
R
F
D
P
A
F
A
T
Q
--
R
R
-
I
T
P
E
T
H
N
-
K
-
V
T
-
E
G
H
L
S
M
T
G
QALFS
E
V
H
V
E
P
G
T
V
F
I
G
R
A
E
L
V
DL
T
E
P
E
L
V
A
T
L
Y
S
L
A
T
L
R
E
L
G
---
G
--
R
S
G
I
Y
G
T
V
R
V
E
I
L
G
V
K
A
G
K
Y
A
--------
S
--------
T
T
A
--------
Y
---
D
--
L
A
---
A
E
N
AGKG
Y
E
E
V
K
K
N
L
K
E
R
L
E
-
K
L
G
F
T
P
V
D
N
S
K
L
L
----
A
A
V
--
D
H
K
D
P
N
G
L
F
K
D
L
W
R
S
S
----
I
D
F
A
E
K
M
V
K
W
V
E
E
L
K
G
G
G
32
HHSearch
62.00
21%
-4
- C4 -
2QKB
4
RNH1_HUMAN
A:
[4-152]
----------------------------------------------------------------------------------------------------------------------------------
M
G
D
F
V
---
V
V
Y
T
D
G
C
C
S
S
N
--
G
R
R
R
P
-
R
A
G
I
G
V
Y
W
-----
G
P
G
H
--
P
---
L
---
N
V
G
I
R
L
-
P
G
R
Q
-
T
N
------------------------------
Q
R
A
E
I
H
A
A
C
K
A
I
E
Q
A
K
T
Q
N
--
I
----
N
K
L
--
V
L
Y
T
N
S
M
F
T
I
N
G
I
T
N
--------
W
V
Q
G
W
K
K
N
G
W
K
T
--------
S
AGK
E
--
V
I
---
N
-------
K
E
D
F
V
A
L
E
R
L
T
Q
-
G
M
--
D
I
Q
W
M
H
V
P
G
----
H
SGF
I
G
N
E
E
A
D
R
L
A
R
E
G
A
K
Q
S
----------------------
37
HHSearch
59.12
18%
-3
- C4 -
4IBN
-
?
A:
[10-170]
-------------------------------------------------------------------------------------------------------------------
S
------------
D
I
P
T
P
L
V
---
A
V
Y
A
D
E
S
C
L
G
N
--
G
R
EGE
N
P
G
G
A
G
V
L
V
-----
E
Y
A
R
P
G
G
A
G
D
I
V
R
R
D
V
W
V
S
E
-
P
-
A
T
-
T
N
------------------------------
N
R
M
A
L
R
S
V
I
E
A
F
R
A
I
G
H
K
G
--
T
---
R
F
R
V
--
V
F
T
T
D
S
R
Y
I
V
D
G
M
T
R
--------
W
V
H
D
W
A
Q
R
G
W
K
R
--------
K
---
S
GA
I
E
---
N
-------
L
A
L
W
Q
E
A
V
Q
A
V
N
-
G
--
H
A
V
E
W
R
W
V
R
G
HAGH
A
----
Q
N
E
Y
A
N
H
L
A
V
T
A
A
G
G
Q
----
T
-----------------
28
HHSearch
58.14
22%
-53
- C4 -
4G1Q
5
?
A:
[432-556]
------------------------------------------------------------------------------------------------------------------
E
K
------------
E
P
I
V
G
A
E
---
T
F
Y
V
D
G
A
A
N
R
E
--
T
K
----
L
G
K
A
G
Y
V
T
-----
N
K
G
R
Q
K
V
---
V
-------
P
L
-
T
-
N
T
-
T
N
------------------------------
Q
K
T
E
L
Q
A
I
Y
L
A
L
Q
D
S
G
----------
L
E
V
--
N
I
V
T
D
S
Q
Y
A
L
G
I
I
Q
A
--------
Q
-------------------
P
---
D
--
K
S
---
E
-------
S
E
L
V
N
Q
I
I
E
Q
L
I
-
K
K
E
-
K
V
Y
L
A
W
V
P
A
----
H
KGIG
G
N
E
Q
V
D
K
L
V
S
A
---------------------------
27
HHSearch
53.78
20%
-24
- C4 -
3QIO
4
RNH_ECOLI
A:
[7-148]
--------------------------------------------------------------------------------------------------------------------------------
E
P
I
V
G
A
E
---
T
F
Y
V
D
G
A
A
N
R
E
--
T
K
----
L
G
K
A
G
Y
V
T
-----
N
R
G
R
Q
----------
K
V
V
T
L
-
T
-
D
T
-
T
N
------------------------------
Q
K
T
E
L
Q
A
I
Y
L
A
L
Q
D
S
G
----------
L
E
V
--
N
I
V
T
D
S
Q
Y
A
L
G
I
I
T
Q
W
I
H
N
W
KK---------------------------------
N
-------
V
D
L
V
N
Q
I
I
E
Q
L
I
-
K
K
E
-
K
V
Y
L
A
W
V
P
A
----
H
KGI
G
G
N
E
Q
V
D
K
L
V
S
A
G
I
R
K
V
----------------------