@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu22440: (2016-07-04 )
MRSTLRKDLIELFSQAGNEFISGQKISDALGCSRTAVWKHIEELRKEGYEVEAVRRKGYRLIKKPGKLSESEIRFGLKTEVMGQHLIYHDVLSSTQKTAHELANNNAPEGTLVVADKQTAGRGRMSRVWHSQEGNGVWMSLILRPDIPLQKTPQLTLLAAVAVVQGIEEAAGIQTDIKWPNDILINGKKTVGILTEMQAEEDRVRSVIIGIGINVNQQPNDFPDELKDIATSLSQAAGEKIDRAGVIQHILLCFEKRYRDYMTHGFTPIKLLWESYALGIGTNMRARTLNGTFYGKALGIDDEGVLLLETNEGIKKIYSADIELG
Atome Classification :
(53 SA)
.........10........20........30........40........50........60........70........80...-.....90........100........110.......120.......130.......140.......150.......160.......170.......180...----..----..190.......200.......210......-.220.......230.......240.......250.......260..--.....270--.......280.......-----290........300.......310.-......320...--
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
R
S
T
L
R
K
D
L
I
E
L
F
S
QAGNEFISGQK
I
S
D
A
LGC
S
R
T
A
V
W
K
H
I
E
E
L
R
KEGY
E
V
E
A
V
R
R
KGY
R
L
IKKPGKL
S
E
S
E
I
RFGL
K
T
E
V
MG
Q
-
H
L
I
Y
H
D
V
L
S
S
T
Q
K
T
A
H
E
-
L
ANNNAPE
G
T
L
V
V
A
DKQTAGR
G
R
M
S
R
V
WHSQEGN
G
V
W
M
S
L
I
LRPDIPLQKTP
Q
L
T
L
L
A
A
V
A
V
V
Q
G
I
E
E
A
AGIQTDIKWP
N
D
I
L
I----NG----
K
K
T
V
G
I
L
TEMQA
E
E
D
R
V
R
S
V
I
I
G
I
G
I
NVNQQ-PND
F
P
D
E
L
K
D
I
A
T
S
L
S
Q
A
AGEKI
D
R
A
G
V
I
Q
H
I
L
L
C
F
E
K
R
Y
R
D
Y
M
TH--G
F
T
P
I
K
L
L
--
W
E
S
Y
ALGIGTN
M
R
A
R
TL-----N
G
-
T
F
YGKALGIDDE
G
V
L
L
L
ETNE
G
-
I
K
K
I
Y
SADIELG--
77
Fugue
77.73
30%
-113
- C5 -
3RKX
-
?
A:
[3-323]
---
K
Y
S
Q
D
V
L
Q
L
L
Y
K
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
Q
L
P
D
I
W
Y
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
F
D
-
F
S
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
-
S
L
V
G
-
N
Q
S
S
F
F
I
L
S
D
E
Q
T
S
------------
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
F
N
L
F
I
A
L
G
I
R
D
A
I
Q
H
F
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
----
D
N
----
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
Q
Q
-
L
E
N
F
D
E
S
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
Q
F
L
T
L
--
P
F
S
E
I
R
E
E
--
Y
N
A
A
S
N
I
W
N
R
T
L
L
F
T
E
------
N
K
-
Q
F
K
G
Q
A
I
D
L
D
Y
D
G
Y
L
I
V
R
D
E
A
G
E
S
H
R
L
I
S
A
D
I
D
F
---
11
PsiBlast_PDB
77.45
33%
-26
- C5 -
3V8L
1
?
A:
[8-329]
--
S
K
Y
S
Q
D
V
L
Q
L
L
Y
K
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
Q
L
P
D
I
W
Y
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
F
D
-
F
S
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
G
N
Q
S
--
S
F
F
I
L
S
D
E
Q
T
K
G
R
G
R
F
N
R
H
W
S
S
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
F
N
L
F
I
A
L
G
I
R
D
A
I
Q
H
F
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
----
D
N
----
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
Q
Q
-
L
E
N
F
D
E
S
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
Q
F
L
T
L
--
P
F
S
E
I
R
-----
E
E
Y
I
--
A
A
S
N
I
W
N
R
T
L
L
F
T
E
N
D
K
-
Q
F
K
G
Q
A
I
D
L
D
Y
D
G
Y
L
I
V
R
D
E
A
G
E
S
H
R
L
I
S
A
D
I
D
F
---
8
PsiBlast_PDB
76.68
33%
-30
- C5 -
3V7R
1
?
A:
[8-329]
--
S
K
Y
S
Q
D
V
L
Q
L
L
Y
K
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
Q
L
P
D
I
W
Y
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
F
D
-
F
S
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
G
N
Q
S
--
S
F
F
I
L
S
D
E
Q
T
K
G
R
G
R
F
N
R
H
W
S
S
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
F
N
L
F
I
A
L
G
I
R
D
A
I
Q
H
F
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
----
D
N
----
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
Q
Q
-
L
E
N
F
D
E
S
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
Q
F
L
T
L
--
P
F
S
E
I
R
-----
E
E
Y
I
--
A
A
S
N
I
W
N
R
T
L
L
F
T
E
N
D
K
-
Q
F
K
G
Q
A
I
D
L
D
Y
D
G
Y
L
I
V
R
D
E
A
G
E
S
H
R
L
I
S
A
D
I
D
F
---
12
PsiBlast_PDB
76.51
33%
-26
- C5 -
4DQ2
1
?
A:
[1-322]
--
S
K
Y
S
Q
D
V
L
Q
L
L
Y
K
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
Q
L
P
D
I
W
Y
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
F
D
-
F
S
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
G
N
Q
S
--
S
F
F
I
L
S
D
E
Q
T
K
G
R
G
R
F
N
R
H
W
S
S
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
F
N
L
F
I
A
L
G
I
R
D
A
I
Q
H
F
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
----
D
N
----
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
Q
Q
-
L
E
N
F
D
E
S
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
Q
F
L
T
L
--
P
F
S
E
I
R
-----
E
E
Y
I
--
A
A
S
N
I
W
N
R
T
L
L
F
T
E
N
D
K
-
Q
F
K
G
Q
A
I
D
L
D
Y
D
G
Y
L
I
V
R
D
E
A
G
E
S
H
R
L
I
S
A
D
I
D
F
---
3
PsiBlast_PDB
76.44
33%
-27
- C5 -
3RKW
1
?
A:
[2-323]
--
S
K
Y
S
Q
D
V
L
Q
L
L
Y
K
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
Q
L
P
D
I
W
Y
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
F
D
-
F
S
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
G
N
Q
S
--
S
F
F
I
L
S
D
E
Q
T
K
G
R
G
R
F
N
R
H
W
S
S
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
F
N
L
F
I
A
L
G
I
R
D
A
I
Q
H
F
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
----
D
N
----
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
Q
Q
-
L
E
N
F
D
E
S
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
Q
F
L
T
L
--
P
F
S
E
I
R
-----
E
E
Y
--
N
A
A
S
N
I
W
N
R
T
L
L
F
T
E
N
D
K
-
Q
F
K
G
Q
A
I
D
L
D
Y
D
G
Y
L
I
V
R
D
E
A
G
E
S
H
R
L
I
S
A
D
I
D
F
---
6
PsiBlast_PDB
76.39
33%
-26
- C5 -
3V7C
1
?
A:
[2-323]
--
S
K
Y
S
Q
D
V
L
Q
L
L
Y
K
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
Q
L
P
D
I
W
Y
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
F
D
-
F
S
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
G
N
Q
S
--
S
F
F
I
L
S
D
E
Q
T
K
G
R
G
R
F
N
R
H
W
S
S
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
F
N
L
F
I
A
L
G
I
R
D
A
I
Q
H
F
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
----
D
N
----
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
Q
Q
-
L
E
N
F
D
E
S
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
Q
F
L
T
L
--
P
F
S
E
I
R
-----
E
E
Y
I
--
A
A
S
N
I
W
N
R
T
L
L
F
T
E
N
D
K
-
Q
F
K
G
Q
A
I
D
L
D
Y
D
G
Y
L
I
V
R
D
E
A
G
E
S
H
R
L
I
S
A
D
I
D
F
---
10
PsiBlast_PDB
76.38
33%
-26
- C5 -
3V8K
1
?
A:
[8-329]
--
S
K
Y
S
Q
D
V
L
Q
L
L
Y
K
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
Q
L
P
D
I
W
Y
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
F
D
-
F
S
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
G
N
Q
S
--
S
F
F
I
L
S
D
E
Q
T
K
G
R
G
R
F
N
R
H
W
S
S
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
F
N
L
F
I
A
L
G
I
R
D
A
I
Q
H
F
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
----
D
N
----
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
Q
Q
-
L
E
N
F
D
E
S
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
Q
F
L
T
L
--
P
F
S
E
I
R
-----
E
E
Y
I
--
A
A
S
N
I
W
N
R
T
L
L
F
T
E
N
D
K
-
Q
F
K
G
Q
A
I
D
L
D
Y
D
G
Y
L
I
V
R
D
E
A
G
E
S
H
R
L
I
S
A
D
I
D
F
---
5
PsiBlast_PDB
76.22
33%
-23
- C5 -
3RKY
1
?
A:
[2-323]
--
S
K
Y
S
Q
D
V
L
Q
L
L
Y
K
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
Q
L
P
D
I
W
Y
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
F
D
-
F
S
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
G
N
Q
S
--
S
F
F
I
L
S
D
E
Q
T
K
G
R
G
R
F
N
R
H
W
S
S
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
F
N
L
F
I
A
L
G
I
R
D
A
I
Q
H
F
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
----
D
N
----
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
Q
Q
-
L
E
N
F
D
E
S
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
Q
F
L
T
L
--
P
F
S
E
I
R
-----
E
E
Y
--
N
A
A
S
N
I
W
N
R
T
L
L
F
T
E
N
D
K
-
Q
F
K
G
Q
A
I
D
L
D
Y
D
G
Y
L
I
V
R
D
E
A
G
E
S
H
R
L
I
S
A
D
I
D
F
---
7
PsiBlast_PDB
76.07
33%
-32
- C5 -
3V7S
1
?
A:
[2-323]
--
S
K
Y
S
Q
D
V
L
Q
L
L
Y
K
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
Q
L
P
D
I
W
Y
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
F
D
-
F
S
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
G
N
Q
S
--
S
F
F
I
L
S
D
E
Q
T
K
G
R
G
R
F
N
R
H
W
S
S
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
F
N
L
F
I
A
L
G
I
R
D
A
I
Q
H
F
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
----
D
N
----
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
Q
Q
-
L
E
N
F
D
E
S
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
Q
F
L
T
L
--
P
F
S
E
I
R
-----
E
E
Y
I
--
A
A
S
N
I
W
N
R
T
L
L
F
T
E
N
D
K
-
Q
F
K
G
Q
A
I
D
L
D
Y
D
G
Y
L
I
V
R
D
E
A
G
E
S
H
R
L
I
S
A
D
I
D
F
---
1
PsiBlast_PDB
75.92
33%
-23
- C5 -
4HA8
1
?
A:
[7-328]
--
S
K
Y
S
Q
D
V
L
Q
L
L
Y
K
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
Q
L
P
D
I
W
Y
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
F
D
-
F
S
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
G
N
Q
S
--
S
F
F
I
L
S
D
E
Q
T
K
G
R
G
R
F
N
R
H
W
S
S
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
F
N
L
F
I
A
L
G
I
R
D
A
I
Q
H
F
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
----
D
N
----
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
Q
Q
-
L
E
N
F
D
E
S
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
Q
F
L
T
L
--
P
F
S
E
I
R
-----
E
E
Y
--
N
A
A
S
N
I
W
N
R
T
L
L
F
T
E
N
D
K
-
Q
F
K
G
Q
A
I
D
L
D
Y
D
G
Y
L
I
V
R
D
E
A
G
E
S
H
R
L
I
S
A
D
I
D
F
---
2
PsiBlast_PDB
75.10
33%
-25
- C5 -
3RIR
1
?
A:
[2-323]
--
S
K
Y
S
Q
D
V
L
Q
L
L
Y
K
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
Q
L
P
D
I
W
Y
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
F
D
-
F
S
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
G
N
Q
S
--
S
F
F
I
L
S
D
E
Q
T
K
G
R
G
R
F
N
R
H
W
S
S
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
F
N
L
F
I
A
L
G
I
R
D
A
I
Q
H
F
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
----
D
N
----
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
Q
Q
-
L
E
N
F
D
E
S
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
Q
F
L
T
L
--
P
F
S
E
I
R
-----
E
E
Y
--
N
A
A
S
N
I
W
N
R
T
L
L
F
T
E
N
D
K
-
Q
F
K
G
Q
A
I
D
L
D
Y
D
G
Y
L
I
V
R
D
E
A
G
E
S
H
R
L
I
S
A
D
I
D
F
---
9
PsiBlast_PDB
74.52
33%
-43
- C5 -
3V8J
-
?
A:
[1-322]
--
S
K
Y
S
Q
D
V
L
Q
L
L
Y
K
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
Q
L
P
D
I
W
Y
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
F
D
-
F
S
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
G
N
Q
S
--
S
F
F
I
L
S
D
E
Q
---------------
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
F
N
L
F
I
A
L
G
I
R
D
A
I
Q
H
F
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
----
D
N
----
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
Q
Q
-
L
E
N
F
D
E
S
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
Q
F
L
T
L
--
P
F
S
E
I
R
-----
E
E
Y
I
--
A
A
S
N
I
W
N
R
T
L
L
F
T
E
N-
K
-
Q
F
K
G
Q
A
I
D
L
D
Y
D
G
Y
L
I
V
R
D
E
A
G
E
S
H
R
L
I
S
A
D
I
D
F
---
4
PsiBlast_PDB
73.77
33%
-38
- C5 -
3RKX
-
?
A:
[3-323]
---
K
Y
S
Q
D
V
L
Q
L
L
Y
K
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
Q
L
P
D
I
W
Y
Q
G
I
I
D
Q
Y
T
K
S
S
A
L
F
D
-
F
S
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
S
L
V
G
N
Q
S
--
S
F
F
I
L
S
D
E
Q
T
------------
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
F
N
L
F
I
A
L
G
I
R
D
A
I
Q
H
F
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
----
D
N
----
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
Q
Q
-
L
E
N
F
D
E
S
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
Q
F
L
T
L
--
P
F
S
E
I
R
-----
E
E
Y
--
N
A
A
S
N
I
W
N
R
T
L
L
F
T
E
N-
K
-
Q
F
K
G
Q
A
I
D
L
D
Y
D
G
Y
L
I
V
R
D
E
A
G
E
S
H
R
L
I
S
A
D
I
D
F
---
55
HHSearch
73.21
32%
-34
- C5 -
3RKX
-
?
A:
[3-323]
---
K
Y
S
Q
D
V
L
Q
L
L
Y
K
N
K
P
N
Y
I
S
G
Q
S
I
A
E
S
L
N
I
S
R
T
A
V
K
K
V
I
D
Q
L
K
L
E
G
C
K
I
D
S
V
N
H
K
G
H
L
L
Q
Q
L
P
D
I
W
Y
Q
G
I
I
D
Q
Y
T
K
S
-
S
A
L
F
D
F
S
E
V
Y
D
S
I
D
S
T
Q
L
A
A
K
K
-
S
L
V
G
-
N
Q
S
S
F
F
I
L
S
D
E
Q
T
------------
S
K
G
Q
G
L
W
M
S
V
V
L
R
P
N
V
A
F
S
M
I
S
K
F
N
L
F
I
A
L
G
I
R
D
A
I
Q
H
F
S
Q
D
E
V
K
V
K
W
P
N
D
I
Y
I
----
D
N
----
G
K
V
C
G
F
L
T
E
M
V
A
N
N
D
G
I
E
A
I
I
C
G
I
G
I
N
L
T
Q
Q
-
L
E
N
F
D
E
S
I
R
H
R
A
T
S
I
Q
L
H
D
K
N
K
L
D
R
Y
Q
F
L
E
R
L
L
Q
E
I
E
K
R
Y
N
Q
F
L
T
L
--
P
F
S
E
I
R
E
E
--
Y
N
A
A
S
N
I
W
N
R
T
L
L
F
T
E
N
------
K
-
Q
F
K
G
Q
A
I
D
L
D
Y
D
G
Y
L
I
V
R
D
E
A
G
E
S
H
R
L
I
S
A
D
I
D
F
---
56
HHSearch
72.08
28%
-119
- C5 -
1BIA
-
BIRA_ECOLI
A:
[3-316]
-
D
N
T
V
P
L
K
L
I
A
L
L
A
--
N
G
E
F
H
S
G
E
Q
L
G
E
T
L
G
M
S
R
A
A
I
N
K
H
I
Q
T
L
R
D
W
G
V
D
V
F
T
V
P
G
K
G
Y
S
L
P
E
P
I
Q
L
L
N
A
K
Q
I
L
G
Q
L
D
----
G
G
-
S
V
A
V
L
P
V
I
D
S
T
N
Q
Y
L
L
D
-
R
I
G
E
L
-
K
S
G
D
A
C
I
A
E
Y
Q
Q
A
G
---------
S
P
F
G
A
N
L
Y
L
S
M
F
W
R
L
E
Q
-
P
A
A
A
I
G
L
S
L
V
I
G
I
V
M
A
E
V
L
R
K
L
G
A
D
K
V
R
V
K
W
P
N
D
L
Y
L
----
Q
D
----
R
K
L
A
G
I
L
V
E
L
T
G
----
A
A
Q
I
V
I
G
A
G
I
N
M
A
M
-------------
W
I
T
L
Q
E
A
-
G
I
N
L
D
R
N
T
L
A
A
M
L
I
R
E
L
R
A
A
L
E
L
F
E
Q
E
--
G
L
A
P
Y
L
S
R
--
W
E
K
L
D
N
F
I
N
R
P
V
K
L
I
I
G
-----
D
K
-
E
I
F
G
I
S
R
G
I
D
K
Q
G
A
L
L
L
E
Q
-
D
G
I
I
K
P
W
M
G
G
E
I
S
L
---
78
Fugue
69.82
35%
-109
* C5 *
1WNL
2
?
A:
[1-235]
-------------------------------------------------------------------------
M
L
G
L
K
T
S
I
I
G
R
-
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
K
T
----
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
-
S
I
D
G
R
I
K
W
P
N
D
V
L
V
----
N
Y
----
K
K
I
A
G
V
L
V
E
G
K
G
D
-----
K
I
V
L
G
I
G
L
N
V
N
N
K
-
V
-------
P
N
G
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
--
P
M
D
I
L
N
L
V
--
R
D
N
M
I
L
G
V
R
V
K
I
L
G
--------
D
G
-
S
F
E
G
I
A
E
D
I
D
D
F
G
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
R
F
L
24
PsiBlast_CBE
67.44
34%
-80
- C5 -
1X01
3
?
B:
[2-232]
--------------------------------------------------------------------------
L
G
L
K
T
S
I
I
G
R
-
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
K
----
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
----
N
Y
----
K
K
I
A
G
V
L
V
E
G
K
G
D
K
-----
I
V
L
G
I
G
L
N
V
N
N
K
V
P
N
G
--------
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
--
P
M
D
I
L
N
L
V
--
R
D
N
M
I
L
G
V
----
R
V
K
I
L
G----
D
G
-
S
F
E
G
I
A
E
D
I
D
D
F
G
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
---
16
PsiBlast_PDB
67.15
34%
-82
- C5 -
1X01
1
?
A:
[2-232]
--------------------------------------------------------------------------
L
G
L
K
T
S
I
I
G
R
-
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
K
----
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
----
N
Y
----
K
K
I
A
G
V
L
V
E
G
K
G
D
K
-----
I
V
L
G
I
G
L
N
V
N
N
K
V
P
N
G
--------
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
--
P
M
D
I
L
N
L
V
--
R
D
N
M
I
L
G
V
----
R
V
K
I
L
G
----
D
G
-
S
F
E
G
I
A
E
D
I
D
D
F
G
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
---
25
PsiBlast_CBE
67.05
34%
-77
- C5 -
1WQW
1
?
B:
[2-232]
--------------------------------------------------------------------------
L
G
L
K
T
S
I
I
G
R
-
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
K
----
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
----
N
Y
----
K
K
I
A
G
V
L
V
E
G
K
G
D
K
-----
I
V
L
G
I
G
L
N
V
N
N
K
V
P
N
G
--------
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
--
P
M
D
I
L
N
L
V
--
R
D
N
M
I
L
G
V
----
R
V
K
I
L
G----
D
G
-
S
F
E
G
I
A
E
D
I
D
D
F
G
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
---
13
PsiBlast_PDB
66.80
34%
-80
- C5 -
1WNL
2
?
A:
[2-232]
--------------------------------------------------------------------------
L
G
L
K
T
S
I
I
G
R
-
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
K
----
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
----
N
Y
----
K
K
I
A
G
V
L
V
E
G
K
G
D
K
-----
I
V
L
G
I
G
L
N
V
N
N
K
V
P
N
G
--------
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
--
P
M
D
I
L
N
L
V
--
R
D
N
M
I
L
G
V
----
R
V
K
I
L
G
----
D
G
-
S
F
E
G
I
A
E
D
I
D
D
F
G
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
---
26
PsiBlast_CBE
66.78
34%
-79
- C5 -
1WNL
2
?
B:
[2-232]
--------------------------------------------------------------------------
L
G
L
K
T
S
I
I
G
R
-
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
K
----
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
----
N
Y
----
K
K
I
A
G
V
L
V
E
G
K
G
D
K
-----
I
V
L
G
I
G
L
N
V
N
N
K
V
P
N
G
--------
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
--
P
M
D
I
L
N
L
V
--
R
D
N
M
I
L
G
V
----
R
V
K
I
L
G----
D
G
-
S
F
E
G
I
A
E
D
I
D
D
F
G
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
---
46
PsiBlast_CBE
66.72
33%
-84
- C5 -
2E41
1
?
A:
[2-232]
--------------------------------------------------------------------------
L
G
L
K
T
S
I
I
G
R
-
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
K
----
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
A
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
----
N
Y
----
K
A
I
A
G
V
L
V
E
G
K
G
D
K
-----
I
V
L
G
I
G
L
N
V
N
N
K
V
P
N
G
--------
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
--
P
M
D
I
L
N
L
V
--
R
D
N
M
I
L
G
V
----
R
V
K
I
L
G
----
D
G
-
S
F
E
G
I
A
E
D
I
D
D
F
G
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
---
19
PsiBlast_PDB
66.47
34%
-78
- C5 -
2DTI
3
?
A:
[2-232]
--------------------------------------------------------------------------
L
G
L
K
T
S
I
I
G
R
-
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
K
----
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
----
N
Y
----
K
K
I
A
G
V
L
V
E
G
K
G
D
K
-----
I
V
L
G
I
G
L
N
V
N
N
K
V
P
N
G
--------
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
--
P
M
D
I
L
N
L
V
--
R
D
N
M
I
L
G
V
----
R
V
K
I
L
G
----
D
G
-
S
F
E
G
I
A
E
D
I
D
D
F
G
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
---
31
PsiBlast_CBE
66.24
33%
-83
- C5 -
2DEQ
1
?
A:
[2-232]
--------------------------------------------------------------------------
L
G
L
K
T
S
I
I
G
R
-
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
K
----
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
----
N
Y
----
K
G
I
A
G
V
L
V
E
G
K
G
D
K
-----
I
V
L
G
I
G
L
N
V
N
N
K
V
P
N
G
--------
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
--
P
M
D
I
L
N
L
V
--
R
D
N
M
I
L
G
V
----
R
V
K
I
L
G
----
D
G
-
S
F
E
G
I
A
E
D
I
D
D
F
G
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
---
15
PsiBlast_PDB
66.23
34%
-80
- C5 -
1WQW
1
?
A:
[2-232]
--------------------------------------------------------------------------
L
G
L
K
T
S
I
I
G
R
-
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
K
----
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
----
N
Y
----
K
K
I
A
G
V
L
V
E
G
K
G
D
K
-----
I
V
L
G
I
G
L
N
V
N
N
K
V
P
N
G
--------
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
--
P
M
D
I
L
N
L
V
--
R
D
N
M
I
L
G
V
----
R
V
K
I
L
G
----
D
G
-
S
F
E
G
I
A
E
D
I
D
D
F
G
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
---
20
PsiBlast_PDB
66.17
34%
-76
- C5 -
1WPY
1
?
A:
[2-232]
--------------------------------------------------------------------------
L
G
L
K
T
S
I
I
G
R
-
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
K
----
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
----
N
Y
----
K
K
I
A
G
V
L
V
E
G
K
G
D
K
-----
I
V
L
G
I
G
L
N
V
N
N
K
V
P
N
G
--------
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
--
P
M
D
I
L
N
L
V
--
R
D
N
M
I
L
G
V
----
R
V
K
I
L
G
----
D
G
-
S
F
E
G
I
A
E
D
I
D
D
F
G
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
---
50
PsiBlast_CBE
66.10
35%
-111
- C5 -
3EFS
5
?
A:
[2-230]
----------------------------------------------------------------------------------
F
K
-
N
L
I
W
L
K
E
V
D
S
T
Q
E
R
L
K
E
-
W
---
N
V
S
Y
G
T
A
L
V
A
D
R
Q
T
K
G
R
G
R
L
G
R
K
W
L
S
Q
E
G
-
G
L
Y
F
S
F
L
L
N
P
K
-
E
F
E
N
L
L
Q
L
P
L
V
L
G
L
S
V
S
E
A
L
E
E
I
T
E
I
P
F
S
L
K
W
P
N
D
V
Y
F
----
Q
E
----
K
K
V
S
G
V
L
R
E
L
S
K
D
K
-----
L
I
V
G
I
G
I
N
V
N
Q
R
---
E
I
P
E
E
I
K
D
R
A
T
T
L
Y
E
I
T
G
K
D
W
D
R
K
E
V
L
L
K
V
L
K
R
I
S
E
N
L
K
K
F
K
E
K
--
S
F
K
E
F
K
G
K
--
I
E
S
K
M
L
Y
L
G
E
E
V
K
L
L
G
------
E
G
-
K
I
T
G
K
L
V
G
L
S
E
K
G
G
A
L
I
L
T
E
E
G
-
I
K
E
I
L
S
G
E
F
S
L
---
21
PsiBlast_CBE
66.06
34%
-74
- C5 -
2DTI
3
?
B:
[2-232]
--------------------------------------------------------------------------
L
G
L
K
T
S
I
I
G
R
-
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
K
----
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
----
N
Y
----
K
K
I
A
G
V
L
V
E
G
K
G
D
K
-----
I
V
L
G
I
G
L
N
V
N
N
K
V
P
N
G
--------
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
--
P
M
D
I
L
N
L
V
--
R
D
N
M
I
L
G
V
----
R
V
K
I
L
G----
D
G
-
S
F
E
G
I
A
E
D
I
D
D
F
G
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
---
17
PsiBlast_PDB
66.04
34%
-83
- C5 -
2DKG
3
?
A:
[2-232]
--------------------------------------------------------------------------
L
G
L
K
T
S
I
I
G
R
-
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
K
----
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
----
N
Y
----
K
K
I
A
G
V
L
V
E
G
K
G
D
K
-----
I
V
L
G
I
G
L
N
V
N
N
K
V
P
N
G
--------
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
--
P
M
D
I
L
N
L
V
--
R
D
N
M
I
L
G
V
----
R
V
K
I
L
G
----
D
G
-
S
F
E
G
I
A
E
D
I
D
D
F
G
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
---
40
PsiBlast_CBE
66.02
33%
-83
- C5 -
2DXT
2
?
A:
[2-232]
--------------------------------------------------------------------------
L
G
L
K
T
S
I
I
G
R
-
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
K
----
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
A
V
L
V
----
N
Y
----
K
K
I
A
G
V
L
V
E
G
K
G
D
K
-----
I
V
L
G
I
G
L
N
V
N
N
K
V
P
N
G
--------
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
--
P
M
D
I
L
N
L
V
--
R
D
N
M
I
L
G
V
----
R
V
K
I
L
G
----
D
G
-
S
F
E
G
I
A
E
D
I
D
D
F
G
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
---
49
PsiBlast_CBE
65.99
35%
-110
- C5 -
3EFS
4
?
B:
[2-230]
----------------------------------------------------------------------------------
F
K
-
N
L
I
W
L
K
E
V
D
S
T
Q
E
R
L
K
E
-
W
---
N
V
S
Y
G
T
A
L
V
A
D
R
Q
T
K
G
R
G
R
L
G
R
K
W
L
S
Q
E
G
-
G
L
Y
F
S
F
L
L
N
P
K
-
E
F
E
N
L
L
Q
L
P
L
V
L
G
L
S
V
S
E
A
L
E
E
I
T
E
I
P
F
S
L
K
W
P
N
D
V
Y
F
----
Q
E
----
K
K
V
S
G
V
L
R
E
L
S
K
D
K
-----
L
I
V
G
I
G
I
N
V
N
Q
R
---
E
I
P
E
E
I
K
D
R
A
T
T
L
Y
E
I
T
G
K
D
W
D
R
K
E
V
L
L
K
V
L
K
R
I
S
E
N
L
K
K
F
K
E
K
--
S
F
K
E
F
K
G
K
--
I
E
S
K
M
L
Y
L
G
E
E
V
K
L
L
G
------
E
G
-
K
I
T
G
K
L
V
G
L
S
E
K
G
G
A
L
I
L
T
E
E
G
-
I
K
E
I
L
S
G
E
F
S
L
---
30
PsiBlast_CBE
65.89
33%
-75
- C5 -
2DEQ
1
?
B:
[2-232]
--------------------------------------------------------------------------
L
G
L
K
T
S
I
I
G
R
-
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
K
----
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
----
N
Y
----
K
G
I
A
G
V
L
V
E
G
K
G
D
K
-----
I
V
L
G
I
G
L
N
V
N
N
K
V
P
N
G
--------
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
--
P
M
D
I
L
N
L
V
--
R
D
N
M
I
L
G
V
----
R
V
K
I
L
G----
D
G
-
S
F
E
G
I
A
E
D
I
D
D
F
G
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
---
23
PsiBlast_CBE
65.88
34%
-80
- C5 -
2DKG
1
?
B:
[2-232]
--------------------------------------------------------------------------
L
G
L
K
T
S
I
I
G
R
-
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
K
----
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
----
N
Y
----
K
K
I
A
G
V
L
V
E
G
K
G
D
K
-----
I
V
L
G
I
G
L
N
V
N
N
K
V
P
N
G
--------
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
--
P
M
D
I
L
N
L
V
--
R
D
N
M
I
L
G
V
----
R
V
K
I
L
G----
D
G
-
S
F
E
G
I
A
E
D
I
D
D
F
G
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
---
29
PsiBlast_CBE
65.82
33%
-83
- C5 -
2DJZ
1
?
A:
[2-232]
--------------------------------------------------------------------------
L
G
L
K
T
S
I
I
G
R
-
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
K
----
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
----
N
Y
----
K
A
I
A
G
V
L
V
E
G
K
G
D
K
-----
I
V
L
G
I
G
L
N
V
N
N
K
V
P
N
G
--------
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
--
P
M
D
I
L
N
L
V
--
R
D
N
M
I
L
G
V
----
R
V
K
I
L
G
----
D
G
-
S
F
E
G
I
A
E
D
I
D
D
F
G
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
---
45
PsiBlast_CBE
65.71
33%
-78
- C5 -
2E41
1
?
B:
[2-232]
--------------------------------------------------------------------------
L
G
L
K
T
S
I
I
G
R
-
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
K
----
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
A
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
----
N
Y
----
K
A
I
A
G
V
L
V
E
G
K
G
D
K
-----
I
V
L
G
I
G
L
N
V
N
N
K
V
P
N
G
--------
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
--
P
M
D
I
L
N
L
V
--
R
D
N
M
I
L
G
V
----
R
V
K
I
L
G----
D
G
-
S
F
E
G
I
A
E
D
I
D
D
F
G
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
---
35
PsiBlast_CBE
65.60
33%
-76
- C5 -
2DVE
1
?
B:
[2-232]
--------------------------------------------------------------------------
L
G
L
K
T
S
I
I
G
R
-
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
K
----
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
A
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
----
N
Y
----
K
K
I
A
G
V
L
V
E
G
K
G
D
K
-----
I
V
L
G
I
G
L
N
V
N
N
K
V
P
N
G
--------
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
--
P
M
D
I
L
N
L
V
--
R
D
N
M
I
L
G
V
----
R
V
K
I
L
G----
D
G
-
S
F
E
G
I
A
E
D
I
D
D
F
G
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
---
36
PsiBlast_CBE
65.57
33%
-81
- C5 -
2DVE
1
?
A:
[2-232]
--------------------------------------------------------------------------
L
G
L
K
T
S
I
I
G
R
-
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
K
----
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
A
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
----
N
Y
----
K
K
I
A
G
V
L
V
E
G
K
G
D
K
-----
I
V
L
G
I
G
L
N
V
N
N
K
V
P
N
G
--------
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
--
P
M
D
I
L
N
L
V
--
R
D
N
M
I
L
G
V
----
R
V
K
I
L
G
----
D
G
-
S
F
E
G
I
A
E
D
I
D
D
F
G
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
---
42
PsiBlast_CBE
65.51
33%
-83
- C5 -
2ZGW
2
?
A:
[2-232]
--------------------------------------------------------------------------
L
G
L
K
T
S
I
I
G
R
-
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
K
----
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
A
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
----
N
Y
----
K
A
I
A
G
V
L
V
E
G
K
G
D
K
-----
I
V
L
G
I
G
L
N
V
N
N
K
V
P
N
G
--------
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
--
P
M
D
I
L
N
L
V
--
R
D
N
M
I
L
G
V
----
R
V
K
I
L
G
----
D
G
-
S
F
E
G
I
A
E
D
I
D
D
F
G
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
---
52
PsiBlast_CBE
65.49
35%
-102
- C5 -
3EFR
4
?
A:
[1-230]
---------------------------------------------------------------------------------
M
F
K
-
N
L
I
W
L
K
E
V
D
S
T
Q
E
R
L
K
E
-
W
---
N
V
S
Y
G
T
A
L
V
A
D
R
Q
T
K
G
R
G
G
L
G
R
K
W
L
S
Q
E
G
-
G
L
Y
F
S
F
L
L
N
P
K
-
E
F
E
N
L
L
Q
L
P
L
V
L
G
L
S
V
S
E
A
L
E
E
I
T
E
I
P
F
S
L
K
W
P
N
D
V
Y
F
----
Q
E
----
K
K
V
S
G
V
L
R
E
L
S
K
D
K
-----
L
I
V
G
I
G
I
N
V
N
Q
R
---
E
I
P
E
E
I
K
D
R
A
T
T
L
Y
E
I
T
G
K
D
W
D
R
K
E
V
L
L
K
V
L
K
R
I
S
E
N
L
K
K
F
K
E
K
--
S
F
K
E
F
K
G
K
--
I
E
S
K
M
L
Y
L
G
E
E
V
K
L
L
G
------
E
G
-
K
I
T
G
K
L
V
G
L
S
E
K
G
G
A
L
I
L
T
E
E
G
-
I
K
E
I
L
S
G
E
F
S
L
---
37
PsiBlast_CBE
65.39
33%
-78
- C5 -
2DZ9
1
?
B:
[2-232]
--------------------------------------------------------------------------
L
G
L
K
T
S
I
I
G
R
-
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
K
----
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
A
V
L
V
----
N
Y
----
K
K
I
A
G
V
L
V
E
G
K
G
D
K
-----
I
V
L
G
I
G
L
N
V
N
N
K
V
P
N
G
--------
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
--
P
M
D
I
L
N
L
V
--
R
D
N
M
I
L
G
V
----
R
V
K
I
L
G----
D
G
-
S
F
E
G
I
A
E
D
I
D
D
F
G
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
---
41
PsiBlast_CBE
65.32
33%
-86
- C5 -
2ZGW
2
?
B:
[2-232]
--------------------------------------------------------------------------
L
G
L
K
T
S
I
I
G
R
-
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
K
----
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
A
L
N
-
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
----
N
Y
----
K
A
I
A
G
V
L
V
E
G
K
G
D
K
-----
I
V
L
G
I
G
L
N
V
N
N
K
V
P
N
G
--------
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
--
P
M
D
I
L
N
L
V
--
R
D
N
M
I
L
G
V
----
R
V
K
I
L
G
----
D
G
-
S
F
E
G
I
A
E
D
I
D
D
F
G
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
---
22
PsiBlast_CBE
65.30
34%
-77
- C5 -
2DTH
2
?
B:
[2-232]
--------------------------------------------------------------------------
L
G
L
K
T
S
I
I
G
R
-
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
K
----
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
----
N
Y
----
K
K
I
A
G
V
L
V
E
G
K
G
D
K
-----
I
V
L
G
I
G
L
N
V
N
N
K
V
P
N
G
--------
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
--
P
M
D
I
L
N
L
V
--
R
D
N
M
I
L
G
V
----
R
V
K
I
L
G----
D
G
-
S
F
E
G
I
A
E
D
I
D
D
F
G
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
---
18
PsiBlast_PDB
65.26
34%
-77
- C5 -
2DTH
2
?
A:
[2-232]
--------------------------------------------------------------------------
L
G
L
K
T
S
I
I
G
R
-
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
K
----
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
----
N
Y
----
K
K
I
A
G
V
L
V
E
G
K
G
D
K
-----
I
V
L
G
I
G
L
N
V
N
N
K
V
P
N
G
--------
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
--
P
M
D
I
L
N
L
V
--
R
D
N
M
I
L
G
V
----
R
V
K
I
L
G
----
D
G
-
S
F
E
G
I
A
E
D
I
D
D
F
G
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
---
44
PsiBlast_CBE
65.25
33%
-79
- C5 -
2EJF
4
?
A:
[2-232]
--------------------------------------------------------------------------
L
G
L
K
T
S
I
I
G
R
-
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
K
----
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
A
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
----
N
Y
----
K
A
I
A
G
V
L
V
E
G
K
G
D
K
-----
I
V
L
G
I
G
L
N
V
N
N
K
V
P
N
G
--------
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
--
P
M
D
I
L
N
L
V
--
R
D
N
M
I
L
G
V
----
R
V
K
I
L
G
----
D
G
-
S
F
E
G
I
A
E
D
I
D
D
F
G
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
---
33
PsiBlast_CBE
65.11
33%
-77
- C5 -
2EJG
2
?
A:
[2-232]
--------------------------------------------------------------------------
L
G
L
K
T
S
I
I
G
R
-
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
K
----
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
A
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
----
N
Y
----
K
K
I
A
G
V
L
V
E
G
K
G
D
K
-----
I
V
L
G
I
G
L
N
V
N
N
K
V
P
N
G
--------
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
--
P
M
D
I
L
N
L
V
--
R
D
N
M
I
L
G
V
----
R
V
K
I
L
G--------
F
E
G
I
A
E
D
I
D
D
F
G
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
---
39
PsiBlast_CBE
65.10
33%
-80
- C5 -
2DXT
2
?
B:
[2-232]
--------------------------------------------------------------------------
L
G
L
K
T
S
I
I
G
R
-
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
K
----
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
A
V
L
V
----
N
Y
----
K
K
I
A
G
V
L
V
E
G
K
G
D
K
-----
I
V
L
G
I
G
L
N
V
N
N
K
V
P
N
G
--------
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
--
P
M
D
I
L
N
L
V
--
R
D
N
M
I
L
G
V
----
R
V
K
I
L
G----
D
G
-
S
F
E
G
I
A
E
D
I
D
D
F
G
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
---
51
PsiBlast_CBE
64.98
35%
-101
- C5 -
3EFR
3
?
B:
[1-230]
---------------------------------------------------------------------------------
M
F
K
-
N
L
I
W
L
K
E
V
D
S
T
Q
E
R
L
K
E
-
W
---
N
V
S
Y
G
T
A
L
V
A
D
R
Q
T
K
G
R
G
G
L
G
R
K
W
L
S
Q
E
G
-
G
L
Y
F
S
F
L
L
N
P
K
-
E
F
E
N
L
L
Q
L
P
L
V
L
G
L
S
V
S
E
A
L
E
E
I
T
E
I
P
F
S
L
K
W
P
N
D
V
Y
F
----
Q
E
----
K
K
V
S
G
V
L
R
E
L
S
K
D
K
-----
L
I
V
G
I
G
I
N
V
N
Q
R
---
E
I
P
E
E
I
K
D
R
A
T
T
L
Y
E
I
T
G
K
D
W
D
R
K
E
V
L
L
K
V
L
K
R
I
S
E
N
L
K
K
F
K
E
K
--
S
F
K
E
F
K
G
K
--
I
E
S
K
M
L
Y
L
G
E
E
V
K
L
L
G
------
E
G
-
K
I
T
G
K
L
V
G
L
S
E
K
G
G
A
L
I
L
T
E
E
G
-
I
K
E
I
L
S
G
E
F
S
L
---
28
PsiBlast_CBE
64.47
33%
-79
- C5 -
2DJZ
1
?
B:
[2-232]
--------------------------------------------------------------------------
L
G
L
K
T
S
I
I
G
R
-
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
K
----
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
R
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
----
N
Y
----
K
A
I
A
G
V
L
V
E
G
K
G
D
K
-----
I
V
L
G
I
G
L
N
V
N
N
K
V
P
N
G
--------
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
--
P
M
D
I
L
N
L
V
--
R
D
N
M
I
L
G
V
----
R
V
K
I
L
--------
S
F
E
G
I
A
E
D
I
D
D
F
G
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
L
---
43
PsiBlast_CBE
64.23
33%
-82
- C5 -
2EJF
3
?
B:
[2-231]
--------------------------------------------------------------------------
L
G
L
K
T
S
I
I
G
R
-
R
V
I
Y
F
Q
E
I
T
S
T
N
E
F
A
K
----
T
S
Y
L
E
E
G
T
V
I
V
A
D
K
Q
T
M
G
H
G
A
L
N
R
K
W
E
S
P
E
G
-
G
L
W
L
S
I
V
L
S
P
K
V
P
Q
K
D
L
P
K
I
V
F
L
G
A
V
G
V
V
E
T
L
K
E
F
S
-
I
D
G
R
I
K
W
P
N
D
V
L
V
----
N
Y
----
K
A
I
A
G
V
L
V
E
G
K
G
D
K
-----
I
V
L
G
I
G
L
N
V
N
N
K
V
P
N
G
--------
A
T
S
M
K
L
E
L
G
S
E
V
P
L
L
S
V
F
R
S
L
I
T
N
L
D
R
L
Y
L
N
F
L
K
N
--
P
M
D
I
L
N
L
V
--
R
D
N
M
I
L
G
V
----
R
V
K
I
L
---------
F
E
G
I
A
E
D
I
D
D
F
G
R
L
I
I
R
L
D
S
G
E
V
K
K
V
I
Y
G
D
V
S
----