@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu23260: (2016-07-06 )
MFHPIEEALDALKKGEVIIVVDDEDRENEGDFVALAEHATPEVINFMATHGRGLICTPLSEEIADRLDLHPMVEHNTDSHHTAFTVSIDHRETKTGISAQERSFTVQALLDSKSVPSDFQRPGHIFPLIAKKGGVLKRAGHTEAAVDLAEACGSPGAGVICEIMNEDGTMARVPELIEIAKKHQLKMITIKDLIQYRYNLTTLVEREVDITLPTDFGTFKVYGYTNEVDGKEHVAFVMGDVPFGEEPVLVRVHSECLTGDVFGSHRCDCGPQLHAALNQIAAEGRGVLLYLRQEGRGIGLINKLKAYKLQEQGYDTVEANEALGFLPDLRNYGIGAQILRDLGVRNMKLLTNNPRKIAGLEGYGLSISERVPLQMEAKEHNKKYLQTKMNKLGHLLHF
Atome Classification :
(34 SA)
.........10........20........30........40........50........60........70...---------------..----------------..---.80........--90.-.......100.......110-----..------......120.......130.......140.......150.......160..-.--.--...------------170.......180.......190.......200.......210.......220.......230.......240-....-....250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MFH
P
I
E
E
A
L
D
A
LKKG
E
V
I
I
V
VDDEDRENEG
D
F
V
A
L
AEHA
T
P
E
V
I
N
F
M
A
THGR
G
L
I
CTP
L
S
E
E
I
A
D
R
LDLHPMVE---------------HN----------------TD---SH
H
T
A
F
T
V
S
I
D--HRE-TKTGISAQER
S
F
T
V
Q
A
L
LD------SK------SV
P
S
D
FQRPG
H
I
F
P
L
I
AKKG
G
V
L
KRAGH
T
E
A
A
V
D
L
A
E
A
CGSPG
A
G
V
I
C
E
I
M-N--E--DG
T
------------
M
AR
V
P
E
L
I
E
I
A
K
KHQ
L
K
M
I
T
I
K
D
L
I
Q
Y
R
Y
N
L
T
T
L
V
ER
E
V
D
I
T
LPTDFG
T
F
K
V
Y
G
Y
TNEVDGK
E
H
V
A
F
V
M
GDV--PFGE-E
P
V
L
V
R
V
H
S
E
CLTGDVFGSHRCDC
G
P
Q
L
H
A
A
L
N
Q
I
A
AEG
R
G
V
L
L
Y
L
RQEGRGI
G
L
I
N
K
L
K
A
Y
K
L
Q
E
QGYDTV
E
A
N
E
ALGFLP
D
L
R
NYG
I
G
A
Q
I
L
R
D
LGVRN
M
K
L
LTNNP
R
K
IAGLEGYGLSISERV
P
L
Q
M
E
A
K
EH
N
K
K
Y
L
Q
T
K
M
N
K
L
G
H
L
LHF
51
HHSearch
90.15
56%
-58
- C7 -
4I14
2
RIBBA_MYCTA
A:
[4-383]
-
L
D
S
V
E
R
A
V
A
D
I
A
A
G
K
A
V
I
V
I
D
D
E
D
R
E
N
E
G
D
L
I
F
A
A
E
K
A
T
P
E
M
V
A
F
M
V
R
Y
T
S
G
Y
L
C
V
P
L
D
G
A
I
C
D
R
L
G
L
L
P
M
Y
-------------------------------------------
A
Y
T
V
T
V
D
--
A
R
N
G
I
G
T
G
I
S
A
S
D
R
A
T
T
M
R
L
L
A
D
------
P
T
------
S
V
A
D
D
F
T
R
P
G
H
V
V
P
L
R
A
K
D
G
G
V
L
R
R
P
G
H
T
E
A
A
V
D
L
A
R
M
A
G
L
Q
P
A
G
A
I
C
E
I
V
-
S
QK
D
--
E
G
S
------------
M
A
H
T
D
E
L
R
V
F
A
D
E
H
G
L
A
L
I
T
I
A
D
L
I
E
W
R
R
K
H
E
K
H
I
E
R
V
A
E
A
R
I
P
T
R
H
G
E
F
R
A
I
G
Y
T
S
I
Y
E
D
V
E
H
V
A
L
V
R
G
E
I
--
A
G
D
G
-
D
D
V
L
V
R
V
H
S
E
C
L
T
G
D
V
F
G
S
R
R
C
D
C
G
P
Q
L
D
A
A
L
A
M
V
A
R
E
G
R
G
V
V
L
Y
M
R
---------------------------------------
Y
G
I
G
A
Q
I
L
V
D
L
G
V
R
S
M
R
L
L
T
N
N
P
------
D
G
Y
G
L
H
I
I
E
R
V
P
L
P
------------------------
1
PsiBlast_PDB
89.47
55%
-57
- C7 -
4I14
2
RIBBA_MYCTA
A:
[7-383]
----
V
E
R
A
V
A
D
I
A
A
G
K
A
V
I
V
I
D
D
E
D
R
E
N
E
G
D
L
I
F
A
A
E
K
A
T
P
E
M
V
A
F
M
V
R
Y
T
S
G
Y
L
C
V
P
L
D
G
A
I
C
D
R
L
G
L
L
P
M
Y
-------------------------------------------
A
Y
T
V
T
V
D
--
A
R
N
G
I
G
T
G
I
S
A
S
D
R
A
T
T
M
R
L
L
A
D
------
P
T
------
S
V
A
D
D
F
T
R
P
G
H
V
V
P
L
R
A
K
D
G
G
V
L
R
R
P
G
H
T
E
A
A
V
D
L
A
R
M
A
G
L
Q
P
A
G
A
I
C
E
I
V
-
S
--
Q
KD
E
G
S
------------
M
A
H
T
D
E
L
R
V
F
A
D
E
H
G
L
A
L
I
T
I
A
D
L
I
E
W
R
R
K
H
E
K
H
I
E
R
V
A
E
A
R
I
P
T
R
H
G
E
F
R
A
I
G
Y
T
S
I
Y
E
D
V
E
H
V
A
L
V
R
G
E
I
AG---
D
G
D
D
V
L
V
R
V
H
S
E
C
L
T
G
D
V
F
G
S
R
R
C
D
C
G
P
Q
L
D
A
A
L
A
M
V
A
R
E
G
R
G
V
V
L
Y
M
R
---------------------------------------
Y
G
I
G
A
Q
I
L
V
D
L
G
V
R
S
M
R
L
L
T
N
N
P
------
D
G
Y
G
L
H
I
I
E
R
V
P
L
P
------------------------
55
HHSearch
74.57
57%
-126
- C7 -
4FFJ
7
?
A:
[3-204]
-
Y
R
K
I
Q
E
A
L
E
A
L
Q
K
G
R
L
V
L
V
I
D
D
K
D
--
N
E
G
D
L
I
C
S
A
Q
A
A
T
T
E
N
V
N
F
M
A
T
Y
A
K
G
L
I
C
M
P
M
S
E
S
L
A
N
Q
L
M
L
S
P
M
V
E
-----------------------------------------
T
A
F
T
V
S
I
D
--
Y
K
E
-
T
T
T
G
I
S
A
E
E
R
G
L
T
A
R
M
C
V
A
------
E
D
------
I
T
P
S
D
F
R
R
P
G
H
M
F
P
L
I
A
K
K
G
G
V
L
E
R
N
G
H
T
E
A
T
V
D
L
L
K
L
A
G
L
K
E
C
G
L
C
C
E
I
M
-
N
--
H
--
D
G
K
------------
M
M
R
T
D
D
L
I
Q
F
S
K
K
H
N
I
P
L
I
T
I
K
E
L
Q
E
Y
R
K
V
Y
D
Q
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
74.53
57%
-126
- C7 -
4FFJ
7
?
A:
[3-204]
-
Y
R
K
I
Q
E
A
L
E
A
L
Q
K
G
R
L
V
L
V
I
D
D
K
D
--
N
E
G
D
L
I
C
S
A
Q
A
A
T
T
E
N
V
N
F
M
A
T
Y
A
K
G
L
I
C
M
P
M
S
E
S
L
A
N
Q
L
M
L
S
P
M
V
E
-----------------------------------------
T
A
F
T
V
S
I
D
--
Y
K
E
-
T
T
T
G
I
S
A
E
E
R
G
L
T
A
R
M
C
V
A
------
E
D
------
I
T
P
S
D
F
R
R
P
G
H
M
F
P
L
I
A
K
K
G
G
V
L
E
R
N
G
H
T
E
A
T
V
D
L
L
K
L
A
G
L
K
E
C
G
L
C
C
E
I
M
-
N
--
H
--
D
G
K
------------
M
M
R
T
D
D
L
I
Q
F
S
K
K
H
N
I
P
L
I
T
I
K
E
L
Q
E
Y
R
K
V
Y
D
Q
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
70.91
49%
-90
- C7 -
3LS6
10
RIBB_SALTY
B:
[13-209]
-
F
E
R
V
E
L
A
L
D
A
L
R
E
G
R
G
V
M
V
L
D
D
E
D
R
E
N
E
G
D
M
I
F
P
A
E
T
M
T
V
E
Q
M
A
L
T
I
R
H
G
S
G
I
V
C
L
C
I
T
E
D
R
R
K
Q
L
D
L
P
M
M
V
E
---------------
N
N
----------------
T
S
---
A
Y
G
T
G
F
T
V
T
I
E
--
A
A
E
G
V
T
T
G
V
S
A
A
D
R
V
T
T
V
R
A
A
I
K
------
D
G
------
A
K
P
S
D
L
N
R
P
G
H
V
F
P
L
R
A
Q
A
G
G
V
L
T
R
G
G
H
T
E
A
T
I
D
L
M
T
L
A
G
F
K
P
A
G
V
L
C
E
L
T
-
N
--
D
--
D
G
T
------------
M
A
R
A
P
E
C
I
A
F
A
G
Q
H
N
M
A
V
V
T
I
E
D
L
V
A
Y
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
70.90
49%
-88
- C7 -
3LS6
8
RIBB_SALTY
A:
[13-209]
-
F
E
R
V
E
L
A
L
D
A
L
R
E
G
R
G
V
M
V
L
D
D
E
D
R
E
N
E
G
D
M
I
F
P
A
E
T
M
T
V
E
Q
M
A
L
T
I
R
H
G
S
G
I
V
C
L
C
I
T
E
D
R
R
K
Q
L
D
L
P
M
M
V
E
---------------
N
N
----------------
T
S
---
A
Y
G
T
G
F
T
V
T
I
E
--
A
A
E
G
V
T
T
G
V
S
A
A
D
R
V
T
T
V
R
A
A
I
K
------
D
G
------
A
K
P
S
D
L
N
R
P
G
H
V
F
P
L
R
A
Q
A
G
G
V
L
T
R
G
G
H
T
E
A
T
I
D
L
M
T
L
A
G
F
K
P
A
G
V
L
C
E
L
T
-
N
--
D
--
D
G
T
------------
M
A
R
A
P
E
C
I
A
F
A
G
Q
H
N
M
A
V
V
T
I
E
D
L
V
A
Y
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
PsiBlast_CBE
70.64
46%
-82
- C7 -
4P8E
13
RIBB_VIBCH
B:
[36-232]
----
V
E
N
A
L
Q
A
L
R
E
G
R
G
V
L
L
L
D
D
E
D
R
E
N
E
G
D
I
I
Y
A
V
E
S
L
T
T
A
Q
M
A
L
M
I
R
E
C
S
G
I
V
C
L
C
L
T
E
A
Q
A
D
R
L
A
L
P
P
M
V
V
---------------
N
N
----------------
N
S
---
A
N
Q
T
A
F
T
V
S
I
E
--
A
K
H
G
V
T
T
G
V
S
A
Q
D
R
V
T
T
I
K
T
A
A
N
------
P
Q
------
A
K
P
E
D
L
A
R
P
G
H
V
F
P
L
R
A
R
A
G
G
V
L
A
R
R
G
H
T
E
G
T
V
D
L
M
Q
M
A
G
L
Q
P
A
G
V
L
C
E
L
T
-
N
--
P
--
D
G
S
------------
M
A
K
T
P
E
I
I
E
F
G
K
L
H
N
M
P
V
L
T
I
E
D
M
V
Q
Y
R
I
Q
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
70.13
46%
-80
- C7 -
4P6C
2
RIBB_VIBCH
A:
[37-233]
----
V
E
N
A
L
Q
A
L
R
E
G
R
G
V
L
L
L
D
D
E
D
R
E
N
E
G
D
I
I
Y
A
V
E
S
L
T
T
A
Q
M
A
L
M
I
R
E
C
S
G
I
V
C
L
C
L
T
E
A
Q
A
D
R
L
A
L
P
P
M
V
V
---------------
N
N
----------------
N
S
---
A
N
Q
T
A
F
T
V
S
I
E
--
A
K
H
G
V
T
T
G
V
S
A
Q
D
R
V
T
T
I
K
T
A
A
N
------
P
Q
------
A
K
P
E
D
L
A
R
P
G
H
V
F
P
L
R
A
R
A
G
G
V
L
A
R
R
G
H
T
E
G
T
V
D
L
M
Q
M
A
G
L
Q
P
A
G
V
L
C
E
L
T
-
N
--
P
--
D
G
S
------------
M
A
K
T
P
E
I
I
E
F
G
K
L
H
N
M
P
V
L
T
I
E
D
M
V
Q
Y
R
I
Q
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
54
HHSearch
69.98
50%
-95
- C7 -
1G57
4
RIBB_ECOLI
A:
[13-210]
-
F
E
R
V
E
N
A
L
A
A
L
R
E
G
R
G
V
M
V
L
D
----
E
N
E
G
D
M
I
F
P
A
E
T
M
T
V
E
Q
M
A
L
T
I
R
H
G
S
G
I
V
C
L
C
I
T
E
D
R
R
K
Q
L
D
L
P
M
M
V
E
---------------
N
N
----------------
T
S
---
A
Y
G
T
G
F
T
V
T
I
E
--
A
A
E
G
V
T
T
G
V
S
A
A
D
R
I
T
T
V
R
A
A
I
A
------
D
G
------
A
K
P
S
D
L
N
R
P
G
H
V
F
P
L
R
A
Q
A
G
G
V
L
T
R
G
G
H
T
E
A
T
I
D
L
M
T
L
A
G
F
K
P
A
G
V
L
C
E
L
T
-
N
--
D
--
D
G
T
------------
M
A
R
A
P
E
C
I
E
F
A
N
K
H
N
M
A
L
V
T
I
E
D
L
V
A
Y
R
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
PsiBlast_CBE
69.86
46%
-79
- C7 -
4P6C
2
RIBB_VIBCH
B:
[37-233]
----
V
E
N
A
L
Q
A
L
R
E
G
R
G
V
L
L
L
D
D
E
D
R
E
N
E
G
D
I
I
Y
A
V
E
S
L
T
T
A
Q
M
A
L
M
I
R
E
C
S
G
I
V
C
L
C
L
T
E
A
Q
A
D
R
L
A
L
P
P
M
V
V
---------------
N
N
----------------
N
S
---
A
N
Q
T
A
F
T
V
S
I
E
--
A
K
H
G
V
T
T
G
V
S
A
Q
D
R
V
T
T
I
K
T
A
A
N
------
P
Q
------
A
K
P
E
D
L
A
R
P
G
H
V
F
P
L
R
A
R
A
G
G
V
L
A
R
R
G
H
T
E
G
T
V
D
L
M
Q
M
A
G
L
Q
P
A
G
V
L
C
E
L
T
-
N
--
P
--
D
G
S
------------
M
A
K
T
P
E
I
I
E
F
G
K
L
H
N
M
P
V
L
T
I
E
D
M
V
Q
Y
R
I
Q
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
69.64
49%
-96
- C7 -
3LRJ
1
RIBB_SALTY
B:
[13-209]
-
F
E
R
V
E
L
A
L
D
A
L
R
E
G
R
G
V
M
V
L
D
D
----
N
E
G
D
M
I
F
P
A
E
T
M
T
V
E
Q
M
A
L
T
I
R
H
G
S
G
I
V
C
L
C
I
T
E
D
R
R
K
Q
L
D
L
P
M
M
V
E
---------------
N
N
----------------
T
S
---
A
Y
G
T
G
F
T
V
T
I
E
--
A
A
E
G
V
T
T
G
V
S
A
A
D
R
V
T
T
V
R
A
A
I
K
------
D
G
------
A
K
P
S
D
L
N
R
P
G
H
V
F
P
L
R
A
Q
A
G
G
V
L
T
R
G
G
H
T
E
A
T
I
D
L
M
T
L
A
G
F
K
P
A
G
V
L
C
E
L
T
-
N
--
D
--
D
G
T
------------
M
A
R
A
P
E
C
I
A
F
A
G
Q
H
N
M
A
V
V
T
I
E
D
L
V
A
Y
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
53
HHSearch
69.62
50%
-81
- C7 -
1TKS
-
RIB3_CANAL
A:
[5-203]
-
F
T
P
I
E
E
A
L
E
A
Y
K
N
G
E
F
L
I
V
M
D
D
E
D
R
E
N
E
G
D
L
I
M
A
A
E
L
I
T
Q
E
K
M
A
F
L
V
R
Y
S
S
G
Y
V
C
V
P
L
S
E
E
R
A
N
Q
L
E
L
P
P
M
L
A
----------------------------------------
G
T
A
Y
T
I
T
C
D
--
F
A
E
G
T
T
T
G
I
S
A
H
D
R
A
L
T
T
R
S
L
A
N
------
P
N
------
S
K
P
Q
D
F
I
K
P
G
H
I
L
P
L
R
A
V
P
G
L
L
K
K
R
R
G
H
T
E
A
A
V
Q
L
S
T
L
A
G
L
Q
P
A
G
V
I
C
E
L
V
-
R
--
D
E-
D
G
L
------------
M
M
R
L
D
D
C
I
Q
F
G
K
K
H
G
I
K
I
I
N
I
N
Q
L
V
E
Y
I
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
PsiBlast_CBE
69.62
46%
-84
- C7 -
4P8E
7
RIBB_VIBCH
A:
[36-232]
----
V
E
N
A
L
Q
A
L
R
E
G
R
G
V
L
L
L
D
D
E
D
R
E
N
E
G
D
I
I
Y
A
V
E
S
L
T
T
A
Q
M
A
L
M
I
R
E
C
S
G
I
V
C
L
C
L
T
E
A
Q
A
D
R
L
A
L
P
P
M
V
V
---------------
N
N
----------------
N
S
---
A
N
Q
T
A
F
T
V
S
I
E
--
A
K
H
G
V
T
T
G
V
S
A
Q
D
R
V
T
T
I
K
T
A
A
N
------
P
Q
------
A
K
P
E
D
L
A
R
P
G
H
V
F
P
L
R
A
R
A
G
G
V
L
A
R
R
G
H
T
E
G
T
V
D
L
M
Q
M
A
G
L
Q
P
A
G
V
L
C
E
L
T
-
N
--
P
--
D
G
S
------------
M
A
K
T
P
E
I
I
E
F
G
K
L
H
N
M
P
V
L
T
I
E
D
M
V
Q
Y
R
I
Q
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
PsiBlast_CBE
69.55
46%
-80
- C7 -
4P6P
9
RIBB_VIBCH
B:
[36-232]
----
V
E
N
A
L
Q
A
L
R
E
G
R
G
V
L
L
L
D
D
E
D
R
E
N
E
G
D
I
I
Y
A
V
E
S
L
T
T
A
Q
M
A
L
M
I
R
E
C
S
G
I
V
C
L
C
L
T
E
A
Q
A
D
R
L
A
L
P
P
M
V
V
---------------
N
N
----------------
N
S
---
A
N
Q
T
A
F
T
V
S
I
E
--
A
K
H
G
V
T
T
G
V
S
A
Q
D
R
V
T
T
I
K
T
A
A
N
------
P
Q
------
A
K
P
E
D
L
A
R
P
G
H
V
F
P
L
R
A
R
A
G
G
V
L
A
R
R
G
H
T
E
G
T
V
D
L
M
Q
M
A
G
L
Q
P
A
G
V
L
C
E
L
T
-
N
--
P
--
D
G
S
------------
M
A
K
T
P
E
I
I
E
F
G
K
L
H
N
M
P
V
L
T
I
E
D
M
V
Q
Y
R
I
Q
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
PsiBlast_CBE
69.48
46%
-88
- C7 -
4P77
2
RIBB_VIBCH
B:
[36-232]
----
V
E
N
A
L
Q
A
L
R
E
G
R
G
V
L
L
L
D
D
E
D
R
E
N
E
G
D
I
I
Y
A
V
E
S
L
T
T
A
Q
M
A
L
M
I
R
E
C
S
G
I
V
C
L
C
L
T
E
A
Q
A
D
R
L
A
L
P
P
M
V
V
-----------------------------------------
T
A
F
T
V
S
I
E
--
A
K
H
G
V
T
T
G
V
S
A
Q
D
R
V
T
T
I
K
T
A
A
N
------
P
Q
------
A
K
P
E
D
L
A
R
P
G
H
V
F
P
L
R
A
R
A
G
G
V
L
A
R
R
G
H
T
E
G
T
V
D
L
M
Q
M
A
G
L
Q
P
A
G
V
L
C
E
L
T
-
N
--
P
--
D
G
S
------------
M
A
K
T
P
E
I
I
E
F
G
K
L
H
N
M
P
V
L
T
I
E
D
M
V
Q
Y
R
I
Q
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
69.39
49%
-88
- C7 -
3LQU
1
RIBB_SALTY
A:
[13-209]
-
F
E
R
V
E
L
A
L
D
A
L
R
E
G
R
G
V
M
V
L
D
D
E
D
R
E
N
E
G
D
M
I
F
P
A
E
T
M
T
V
E
Q
M
A
L
T
I
R
H
G
S
G
I
V
C
L
C
I
T
E
D
R
R
K
Q
L
D
L
P
M
M
V
E
---------------
N
N
----------------
T
S
---
A
Y
G
T
G
F
T
V
T
I
E
--
A
A
E
G
V
T
T
G
V
S
A
A
D
R
V
T
T
V
R
A
A
I
K
------
D
G
------
A
K
P
S
D
L
N
R
P
G
H
V
F
P
L
R
A
Q
A
G
G
V
L
T
R
G
G
H
T
E
A
T
I
D
L
M
T
L
A
G
F
K
P
A
G
V
L
C
E
L
T
-
N
--
D
--
D
G
T
------------
M
A
R
A
P
E
C
I
A
F
A
G
Q
H
N
M
A
V
V
T
I
E
D
L
V
A
Y
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
PsiBlast_CBE
69.36
49%
-89
- C7 -
3LQU
1
RIBB_SALTY
B:
[13-209]
-
F
E
R
V
E
L
A
L
D
A
L
R
E
G
R
G
V
M
V
L
D
----
E
N
E
G
D
M
I
F
P
A
E
T
M
T
V
E
Q
M
A
L
T
I
R
H
G
S
G
I
V
C
L
C
I
T
E
D
R
R
K
Q
L
D
L
P
M
M
V
E
---------------
N
N
----------------
T
S
---
A
Y
G
T
G
F
T
V
T
I
E
--
A
A
E
G
V
T
T
G
V
S
A
A
D
R
V
T
T
V
R
A
A
I
K
------
D
G
------
A
K
P
S
D
L
N
R
P
G
H
V
F
P
L
R
A
Q
A
G
G
V
L
T
R
G
G
H
T
E
A
T
I
D
L
M
T
L
A
G
F
K
P
A
G
V
L
C
E
L
T
-
N
--
D
--
D
G
T
------------
M
A
R
A
P
E
C
I
A
F
A
G
Q
H
N
M
A
V
V
T
I
E
D
L
V
A
Y
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
69.36
49%
-99
- C7 -
3LRJ
2
RIBB_SALTY
C:
[13-209]
-
F
E
R
V
E
L
A
L
D
A
L
R
E
G
R
G
V
M
V
L
D
------
E
G
D
M
I
F
P
A
E
T
M
T
V
E
Q
M
A
L
T
I
R
H
G
S
G
I
V
C
L
C
I
T
E
D
R
R
K
Q
L
D
L
P
M
M
V
E
---------------
N
N
----------------
T
S
---
A
Y
G
T
G
F
T
V
T
I
E
--
A
A
E
G
V
T
T
G
V
S
A
A
D
R
V
T
T
V
R
A
A
I
K
------
D
G
------
A
K
P
S
D
L
N
R
P
G
H
V
F
P
L
R
A
Q
A
G
G
V
L
T
R
G
G
H
T
E
A
T
I
D
L
M
T
L
A
G
F
K
P
A
G
V
L
C
E
L
T
-
N
--
D
--
D
G
T
------------
M
A
R
A
P
E
C
I
A
F
A
G
Q
H
N
M
A
V
V
T
I
E
D
L
V
A
Y
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
69.35
46%
-82
- C7 -
4P6P
5
RIBB_VIBCH
A:
[36-232]
----
V
E
N
A
L
Q
A
L
R
E
G
R
G
V
L
L
L
D
D
E
D
R
E
N
E
G
D
I
I
Y
A
V
E
S
L
T
T
A
Q
M
A
L
M
I
R
E
C
S
G
I
V
C
L
C
L
T
E
A
Q
A
D
R
L
A
L
P
P
M
V
V
---------------
N
N
----------------
N
S
---
A
N
Q
T
A
F
T
V
S
I
E
--
A
K
H
G
V
T
T
G
V
S
A
Q
D
R
V
T
T
I
K
T
A
A
N
------
P
Q
------
A
K
P
E
D
L
A
R
P
G
H
V
F
P
L
R
A
R
A
G
G
V
L
A
R
R
G
H
T
E
G
T
V
D
L
M
Q
M
A
G
L
Q
P
A
G
V
L
C
E
L
T
-
N
--
P
--
D
G
S
------------
M
A
K
T
P
E
I
I
E
F
G
K
L
H
N
M
P
V
L
T
I
E
D
M
V
Q
Y
R
I
Q
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
69.26
46%
-82
- C7 -
4P77
3
RIBB_VIBCH
A:
[36-232]
----
V
E
N
A
L
Q
A
L
R
E
G
R
G
V
L
L
L
D
D
E
D
R
E
N
E
G
D
I
I
Y
A
V
E
S
L
T
T
A
Q
M
A
L
M
I
R
E
C
S
G
I
V
C
L
C
L
T
E
A
Q
A
D
R
L
A
L
P
P
M
V
V
---------------
N
N
----------------
N
-----
N
Q
T
A
F
T
V
S
I
E
--
A
K
H
G
V
T
T
G
V
S
A
Q
D
R
V
T
T
I
K
T
A
A
N
------
P
Q
------
A
K
P
E
D
L
A
R
P
G
H
V
F
P
L
R
A
R
A
G
G
V
L
A
R
R
G
H
T
E
G
T
V
D
L
M
Q
M
A
G
L
Q
P
A
G
V
L
C
E
L
T
-
N
--
P
--
D
G
S
------------
M
A
K
T
P
E
I
I
E
F
G
K
L
H
N
M
P
V
L
T
I
E
D
M
V
Q
Y
R
I
Q
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
PsiBlast_CBE
68.58
50%
-81
- C7 -
1TKU
1
RIB3_CANAL
B:
[4-201]
I
F
T
P
I
E
E
A
L
E
A
Y
K
N
G
E
F
L
I
V
M
D
D
E
D
R
E
N
E
G
D
L
I
M
A
A
E
L
I
T
Q
E
K
M
A
F
L
V
R
Y
S
S
G
Y
V
C
V
P
L
S
E
E
R
A
N
Q
L
E
L
P
P
M
L
A
----------------------------------------
G
T
A
Y
T
I
T
C
D
--
F
A
E
G
T
T
T
G
I
S
A
H
D
R
A
L
T
T
R
S
L
A
N
------
P
N
------
S
K
P
Q
D
F
I
K
P
G
H
I
L
P
L
R
A
V
P
G
L
L
K
K
R
R
G
H
T
E
A
A
V
Q
L
S
T
L
A
G
L
Q
P
A
G
V
I
C
E
L
V
R
D
--
E
--
D
G
L
------------
M
M
R
L
D
D
C
I
Q
F
G
K
K
H
G
I
K
I
I
N
I
N
Q
L
V
E
Y
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
68.27
50%
-76
- C7 -
1TKU
1
RIB3_CANAL
A:
[4-201]
I
F
T
P
I
E
E
A
L
E
A
Y
K
N
G
E
F
L
I
V
M
D
D
E
D
R
E
N
E
G
D
L
I
M
A
A
E
L
I
T
Q
E
K
M
A
F
L
V
R
Y
S
S
G
Y
V
C
V
P
L
S
E
E
R
A
N
Q
L
E
L
P
P
M
L
A
----------------------------------------
G
T
A
Y
T
I
T
C
D
--
F
A
E
G
T
T
T
G
I
S
A
H
D
R
A
L
T
T
R
S
L
A
N
------
P
N
------
S
K
P
Q
D
F
I
K
P
G
H
I
L
P
L
R
A
V
P
G
L
L
K
K
R
R
G
H
T
E
A
A
V
Q
L
S
T
L
A
G
L
Q
P
A
G
V
I
C
E
L
V
R
D
--
E
--
D
G
L
------------
M
M
R
L
D
D
C
I
Q
F
G
K
K
H
G
I
K
I
I
N
I
N
Q
L
V
E
Y
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
60
HHSearch
68.19
51%
-80
- C7 -
3MIO
5
RIBBA_MYCTA
A:
[4-203]
-
L
D
S
V
E
R
A
V
A
D
I
A
A
G
K
A
V
I
V
I
D
D
E
D
R
E
N
E
G
D
L
I
F
A
A
E
K
A
T
P
E
M
V
A
F
M
V
R
Y
T
S
G
Y
L
C
V
P
L
D
G
A
I
C
D
R
L
G
L
L
P
M
Y
---------------------------------------------
T
V
T
V
D
--
A
R
N
G
I
G
T
G
I
S
A
S
D
R
A
T
T
M
R
L
L
A
D
------
P
T
------
S
V
A
D
D
F
T
R
P
G
H
V
V
P
L
R
A
K
D
G
G
V
L
R
R
P
G
H
T
E
A
A
V
D
L
A
R
M
A
G
L
Q
P
A
G
A
I
C
E
I
V
-
S
--
Q
KD
E
G
S
------------
M
A
H
T
D
E
L
R
V
F
A
D
E
H
G
L
A
L
I
T
I
A
D
L
I
E
W
R
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
58
HHSearch
68.05
46%
-90
- C7 -
4P6D
2
RIBB_VIBCH
A:
[33-230]
-
I
T
R
V
E
N
A
L
Q
A
L
R
E
G
R
G
V
L
L
L
D
D
E
D
R
E
N
E
G
D
I
I
Y
A
V
E
S
L
T
T
A
Q
M
A
L
M
I
R
E
C
S
G
I
V
C
L
C
L
T
E
A
Q
A
D
R
L
A
L
P
P
-----------------------------------------------
T
V
S
I
E
--
A
K
H
G
V
T
T
G
V
S
A
Q
D
R
V
T
T
I
K
T
A
A
N
------
P
Q
------
A
K
P
E
D
L
A
R
P
G
H
V
F
P
L
R
A
R
A
G
G
V
L
A
R
R
G
H
T
E
G
T
V
D
L
M
Q
M
A
G
L
Q
P
A
G
V
L
C
E
L
T
-
N
--
P
--
D
G
S
------------
M
A
K
T
P
E
I
I
E
F
G
K
L
H
N
M
P
V
L
T
I
E
D
M
V
Q
Y
R
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
67.98
50%
-78
- C7 -
2RIU
1
RIB3_CANAL
A:
[4-201]
I
F
T
P
I
E
E
A
L
E
A
Y
K
N
G
E
F
L
I
V
M
D
D
E
D
R
E
N
E
G
D
L
I
M
A
A
E
L
I
T
Q
E
K
M
A
F
L
V
R
Y
S
S
G
Y
V
C
V
P
L
S
E
E
R
A
N
Q
L
E
L
P
P
M
L
A
----------------------------------------
G
T
A
Y
T
I
T
C
D
--
F
A
E
G
T
T
T
G
I
S
A
H
D
R
A
L
T
T
R
S
L
A
N
------
P
N
------
S
K
P
Q
D
F
I
K
P
G
H
I
L
P
L
R
A
V
P
G
L
L
K
K
R
R
G
H
T
E
A
A
V
Q
L
S
T
L
A
G
L
Q
P
A
G
V
I
C
E
L
V
R
D
--
E
--
D
G
L
------------
M
M
R
L
D
D
C
I
Q
F
G
K
K
H
G
I
K
I
I
N
I
N
Q
L
V
E
Y
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
67.62
46%
-90
- C7 -
4P6D
2
RIBB_VIBCH
A:
[36-232]
----
V
E
N
A
L
Q
A
L
R
E
G
R
G
V
L
L
L
D
D
E
D
R
E
N
E
G
D
I
I
Y
A
V
E
S
L
T
T
A
Q
M
A
L
M
I
R
E
C
S
G
I
V
C
L
C
L
T
E
A
Q
A
D
R
L
A
L
P
P
-----------------------------------------------
T
V
S
I
E
--
A
K
H
G
V
T
T
G
V
S
A
Q
D
R
V
T
T
I
K
T
A
A
N
------
P
Q
------
A
K
P
E
D
L
A
R
P
G
H
V
F
P
L
R
A
R
A
G
G
V
L
A
R
R
G
H
T
E
G
T
V
D
L
M
Q
M
A
G
L
Q
P
A
G
V
L
C
E
L
T
-
N
--
P
--
D
G
S
------------
M
A
K
T
P
E
I
I
E
F
G
K
L
H
N
M
P
V
L
T
I
E
D
M
V
Q
Y
R
I
Q
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
PsiBlast_CBE
67.45
51%
-80
- C7 -
3MIO
6
RIBBA_MYCTA
B:
[7-202]
----
V
E
R
A
V
A
D
I
A
A
G
K
A
V
I
V
I
D
D
E
D
R
E
N
E
G
D
L
I
F
A
A
E
K
A
T
P
E
M
V
A
F
M
V
R
Y
T
S
G
Y
L
C
V
P
L
D
G
A
I
C
D
R
L
G
L
L
P
M
----------------------------------------------
T
V
T
V
D
--
A
R
N
G
I
G
T
G
I
S
A
S
D
R
A
T
T
M
R
L
L
A
D
------
P
T
------
S
V
A
D
D
F
T
R
P
G
H
V
V
P
L
R
A
K
D
G
G
V
L
R
R
P
G
H
T
E
A
A
V
D
L
A
R
M
A
G
L
Q
P
A
G
A
I
C
E
I
V
-
S
--
Q
KD
E
G
S
------------
M
A
H
T
D
E
L
R
V
F
A
D
E
H
G
L
A
L
I
T
I
A
D
L
I
E
W
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
66.98
51%
-83
- C7 -
3MIO
5
RIBBA_MYCTA
A:
[7-202]
----
V
E
R
A
V
A
D
I
A
A
G
K
A
V
I
V
I
D
D
E
D
R
E
N
E
G
D
L
I
F
A
A
E
K
A
T
P
E
M
V
A
F
M
V
R
Y
T
S
G
Y
L
C
V
P
L
D
G
A
I
C
D
R
L
G
L
L
P
M
Y
---------------------------------------------
T
V
T
V
D
--
A
R
N
G
I
G
T
G
I
S
A
S
D
R
A
T
T
M
R
L
L
A
D
------
P
T
------
S
V
A
D
D
F
T
R
P
G
H
V
V
P
L
R
A
K
D
G
G
V
L
R
R
P
G
H
T
E
A
A
V
D
L
A
R
M
A
G
L
Q
P
A
G
A
I
C
E
I
V
-
S
--
Q
KD
E
G
S
------------
M
A
H
T
D
E
L
R
V
F
A
D
E
H
G
L
A
L
I
T
I
A
D
L
I
E
W
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
PsiBlast_CBE
65.41
43%
-56
- C7 -
1K4O
4
RIB3_MAGO7
A:
[12-219]
-
F
D
A
I
P
D
V
I
Q
A
F
K
N
G
E
F
V
V
V
L
D
D
P
S
R
E
N
E
A
D
L
I
I
A
A
E
S
V
T
T
E
Q
M
A
F
M
V
R
H
S
S
G
L
I
C
A
P
L
T
P
E
R
T
T
A
L
D
L
P
Q
M
V
T
---------------
H
N
----------------
A
D
---
P
R
G
T
A
Y
T
V
S
V
D
A
E
H
P
S
-
T
T
T
G
I
S
A
H
D
R
A
L
A
C
R
M
L
A
A
------
P
D
------
A
Q
P
S
H
F
R
R
P
G
H
V
F
P
L
R
A
V
A
G
G
V
R
A
R
R
G
H
T
E
A
G
V
E
L
C
R
L
A
G
K
R
P
V
A
V
I
S
E
I
V
-
D
-----
D
G
Q
EVEGRAVRAA
P
G
M
L
R
G
D
E
C
V
A
F
A
R
R
W
G
L
K
V
C
T
I
E
D
M
I
A
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
57
HHSearch
57.45
37%
-2
- C7 -
1SNN
6
RIBB_METJA
A:
[2-220]
--
N
N
V
E
K
A
I
E
A
L
K
K
G
E
I
I
L
V
Y
D
S
D
E
R
E
G
E
T
D
M
V
V
A
S
Q
F
I
T
P
E
H
I
R
I
M
R
K
D
A
G
G
L
I
C
T
A
L
H
P
D
I
C
N
K
L
G
I
P
F
M
V
D
---------------
I
L
E
F
A
SQKF
K
V
L
R
E
L
YPN
D
I
PY-
D
E
K
S
S
F
S
I
T
I
N
--
H
R
K
-
T
F
T
G
I
T
D
N
D
R
A
F
T
I
K
K
L
A
E
------
L
V
K
E
GRFN
D
F
G
K
E
F
R
S
P
G
S
V
T
L
L
R
A
A
E
G
L
V
K
N
R
Q
G
H
T
E
M
T
V
A
L
A
E
L
A
N
L
V
P
I
T
T
I
C
E
M
M
-
G
--
D
--
D
G
N
------------
A
M
S
K
N
E
T
K
R
Y
A
E
K
H
N
L
I
Y
L
S
G
E
E
I
I
N
Y
Y
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
PsiBlast_CBE
57.24
33%
0
- C7 -
1SNN
3
RIBB_METJA
B:
[4-219]
----
V
E
K
A
I
E
A
L
K
K
G
E
I
I
L
V
Y
D
S
D
E
R
E
G
E
T
D
M
V
V
A
S
Q
F
I
T
P
E
H
I
R
I
M
R
K
D
A
G
G
L
I
C
T
A
L
H
P
D
I
C
N
K
L
G
I
P
F
M
V
D
I
L
E
F
A
SQKF
K
V
L
R
E
L
Y
P
----------------
N
D
IPY
D
E
K
S
S
F
S
I
T
I
N
--
H
R
K
-
T
F
T
G
I
T
D
N
D
R
A
F
T
I
K
K
L
A
E
L
V
K
E
GR
F
N
------
D
F
G
K
E
F
R
S
P
G
S
V
T
L
L
R
A
A
E
G
L
V
K
N
R
Q
G
H
T
E
M
T
V
A
L
A
E
L
A
N
L
V
P
I
T
T
I
C
E
M
M
-
G
--
D
--
D
G
N
------------
A
M
S
K
N
E
T
K
R
Y
A
E
K
H
N
L
I
Y
L
S
G
E
E
I
I
N
Y
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
PsiBlast_CBE
56.78
33%
-3
- C7 -
1PVY
3
RIBB_METJA
B:
[4-219]
----
V
E
K
A
I
E
A
L
K
K
G
E
I
I
L
V
Y
D
S
D
E
R
E
G
E
T
D
M
V
V
A
S
Q
F
I
T
P
E
H
I
R
I
M
R
K
D
A
G
G
L
I
C
T
A
L
H
P
D
I
C
N
K
L
G
I
P
F
M
V
D
I
L
E
F
A
SQKF
K
V
L
R
E
L
Y
P
----------------
N
D
IPY
D
E
K
S
S
F
S
I
T
I
N
--
H
R
K
-
T
F
T
G
I
T
D
N
D
R
A
F
T
I
K
K
L
A
E
L
V
K
E
GR
F
N
------
D
F
G
K
E
F
R
S
P
G
S
V
T
L
L
R
A
A
E
G
L
V
K
N
R
Q
G
H
T
E
M
T
V
A
L
A
E
L
A
N
L
V
P
I
T
T
I
C
E
M
M
-
G
--
D
--
D
G
N
------------
A
M
S
K
N
E
T
K
R
Y
A
E
K
H
N
L
I
Y
L
S
G
E
E
I
I
N
Y
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
PsiBlast_CBE
56.74
33%
1
- C7 -
1PVY
6
RIBB_METJA
A:
[4-219]
----
V
E
K
A
I
E
A
L
K
K
G
E
I
I
L
V
Y
D
S
D
E
R
E
G
E
T
D
M
V
V
A
S
Q
F
I
T
P
E
H
I
R
I
M
R
K
D
A
G
G
L
I
C
T
A
L
H
P
D
I
C
N
K
L
G
I
P
F
M
V
D
I
L
E
F
A
SQKF
K
V
L
R
E
L
Y
P
----------------
N
D
IPY
D
E
K
S
S
F
S
I
T
I
N
--
H
R
K
-
T
F
T
G
I
T
D
N
D
R
A
F
T
I
K
K
L
A
E
L
V
K
E
GR
F
N
------
D
F
G
K
E
F
R
S
P
G
S
V
T
L
L
R
A
A
E
G
L
V
K
N
R
Q
G
H
T
E
M
T
V
A
L
A
E
L
A
N
L
V
P
I
T
T
I
C
E
M
M
-
G
--
D
--
D
G
N
------------
A
M
S
K
N
E
T
K
R
Y
A
E
K
H
N
L
I
Y
L
S
G
E
E
I
I
N
Y
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
PsiBlast_CBE
56.33
33%
1
- C7 -
1SNN
6
RIBB_METJA
A:
[4-219]
----
V
E
K
A
I
E
A
L
K
K
G
E
I
I
L
V
Y
D
S
D
E
R
E
G
E
T
D
M
V
V
A
S
Q
F
I
T
P
E
H
I
R
I
M
R
K
D
A
G
G
L
I
C
T
A
L
H
P
D
I
C
N
K
L
G
I
P
F
M
V
D
I
L
E
F
A
SQKF
K
V
L
R
E
L
Y
P
----------------
N
D
IPY
D
E
K
S
S
F
S
I
T
I
N
--
H
R
K
-
T
F
T
G
I
T
D
N
D
R
A
F
T
I
K
K
L
A
E
L
V
K
E
GR
F
N
------
D
F
G
K
E
F
R
S
P
G
S
V
T
L
L
R
A
A
E
G
L
V
K
N
R
Q
G
H
T
E
M
T
V
A
L
A
E
L
A
N
L
V
P
I
T
T
I
C
E
M
M
-
G
--
D
--
D
G
N
------------
A
M
S
K
N
E
T
K
R
Y
A
E
K
H
N
L
I
Y
L
S
G
E
E
I
I
N
Y
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------