@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu24120: (2016-07-08 )
MSWIVNKQSSQEELAGRFRKLMSAPDILQIPGAHDGMAALLAKEAGFSAIYLSGAAYTASRGLPDLGIITSAEIAERAKDLVRAADLPLLVDIDTGFGGVLNAARTAREMLEARVAAVQMEDQQLPKKCGHLNGKQLVPIKEMAQKIKAIKQAAPSLIVVARTDARAQEGLDAAIKRSEAYIEAGADAIFPEALQAENEFRQFAERIPVPLLANMTEFGKTPYYRADEFEDMGFHMVIYPVTSLRAAAKACERMFGLMKEHGSQKEGLHDMQTRKELYDTISYYDYEALDKTIAKTVLPDE
Atome Classification :
(27 SA)
.........10........20.....-...30........40........50....-....-60.-........70........80...-.-..---..90........-100.......110.......120.......130.......140.......150--...-.--.--....160.......170.......180.......190....-...200.......210.......220.....-..230.......240.......250.......260.......270.......280--.....-...290.......300
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
S
W
I
VNKQS
S
Q
E
E
L
A
G
R
F
R
K
L
MSAP
D
-
I
L
QIPGAH
D
G
M
A
A
L
L
A
K
EAGF
S
A
I
Y
LSGA-
A
Y
TA-S-R-GLPDLGII
T
S
A
E
I
A
E
R
A
K
D
L
V
R
A-A-DL---
P
L
L
V
D
IDTG
F
G
G
-
V
L
N
A
A
R
T
A
R
E
M
L
E
A
R
V
A
A
VQM
E
D
Q
Q
L
P
K
K
CGHLNGKQLV
P
I
K
E
M
A
Q
K
I
K
A
I
----
K
QA-A--P--
S
L
I
V
V
ARTD
A
R
A
Q
E
G
L
D
A
A
I
K
R
S
E
A
Y
I
EAGADAI
F
P
E
A
L
Q
A
-
E
N
E
F
R
Q
F
A
E
RIPV
P
L
L
A
N
M
T
E
FGKTPYYRAD-EFEDMG
F
H
M
V
I
Y
PV
T
S
L
R
A
A
A
K
A
C
E
R
M
F
G
L
M
K
EHG
S
Q
KEG
L
H
D
M
Q
T
R
K
E
L
Y
D
T
I
---
S
Y
Y
D
Y
-
E
A
L
D
K
T
I
A
K
TVLPDE
98
HHSearch
99.07
74%
-105
- C4 -
4IQD
4
?
A:
[9-298]
-----
N
K
Q
S
T
Q
E
E
L
A
N
R
F
R
A
L
V
E
A
N
E
-
I
L
Q
I
P
G
A
H
D
A
M
A
A
L
V
A
R
N
T
G
F
L
A
L
Y
L
S
G
A
-
A
Y
T
A
-
S
-
K
-
G
L
P
D
L
G
I
V
T
S
T
E
V
A
E
R
A
R
D
L
V
R
A
-
T
-
D
L
---
P
V
L
V
D
I
D
T
G
F
G
G
-
V
L
N
V
A
R
T
A
V
E
M
V
E
A
K
V
A
A
V
Q
I
E
D
Q
Q
L
P
K
K
C
G
H
L
N
G
K
K
L
V
T
T
E
E
L
V
Q
K
I
K
A
I
----
K
E
V
-
A
--
P
--
S
L
Y
I
V
A
R
T
D
A
R
G
V
E
G
L
D
E
A
I
E
R
A
N
A
Y
V
K
A
G
A
D
A
I
F
P
E
A
L
Q
S
-
E
E
E
F
R
L
F
N
S
K
V
N
A
P
L
L
A
N
M
T
E
F
G
K
T
P
Y
Y
S
A
E
-
E
F
A
N
M
G
F
Q
M
V
I
Y
P
V
T
S
L
R
V
A
A
K
A
Y
E
N
V
F
T
L
I
K
E
T
G
S
Q
K
D
A
L
S
N
M
Q
T
R
S
E
L
Y
E
T
I
---
S
Y
H
D
F
-
E
E
L
D
T
G
I
A
K
------
1
PsiBlast_PDB
98.20
71%
-105
- C4 -
4IQD
4
?
A:
[9-298]
-----
N
K
Q
S
T
Q
E
E
L
A
N
R
F
R
A
L
V
E
A
N
E
-
I
L
Q
I
P
G
A
H
D
A
M
A
A
L
V
A
R
N
T
G
F
L
A
L
Y
L
S
G
A
-
A
Y
T
A
-
S
-
K
-
G
L
P
D
L
G
I
V
T
S
T
E
V
A
E
R
A
R
D
L
V
R
A
-
T
-
D
L
---
P
V
L
V
D
I
D
T
G
F
G
G
-
V
L
N
V
A
R
T
A
V
E
M
V
E
A
K
V
A
A
V
Q
I
E
D
Q
Q
L
P
K
K
C
G
H
L
N
G
K
K
L
V
T
T
E
E
L
V
Q
K
I
K
A
I
----
K
E
V
-
A
--
P
--
S
L
Y
I
V
A
R
T
D
A
R
G
V
E
G
L
D
E
A
I
E
R
A
N
A
Y
V
K
A
G
A
D
A
I
F
P
E
A
L
Q
S
-
E
E
E
F
R
L
F
N
S
K
V
N
A
P
L
L
A
N
M
T
E
F
G
K
T
P
Y
Y
S
A
E
-
E
F
A
N
M
G
F
Q
M
V
I
Y
P
V
T
S
L
R
V
A
A
K
A
Y
E
N
V
F
T
L
I
K
E
T
G
S
Q
K
D
A
L
S
N
M
Q
T
R
S
E
L
Y
E
T
I
---
S
Y
H
D
F
-
E
E
L
D
T
G
I
A
K
------
2
PsiBlast_PDB
95.30
71%
-103
- C4 -
4IQE
-
?
A:
[4-296]
---
V
V
N
-
Q
S
T
Q
E
E
L
A
N
R
F
R
A
L
V
E
A
N
E
-
I
L
Q
I
P
G
A
H
D
A
M
A
A
L
V
A
R
N
T
G
F
L
A
L
Y
L
S
G
A
-
A
Y
T
A
-
S
-
K
-
G
L
P
D
L
G
I
V
T
S
T
E
V
A
E
R
A
R
D
L
V
R
A
-
T
-
D
L
---
P
V
L
V
D
I
D
T
G
F
G
G
-
V
L
N
V
A
R
T
A
V
E
M
V
E
A
K
V
A
A
V
Q
I
E
D
Q
Q
L
P
K
K
C
---
N
G
K
K
L
V
T
T
E
E
L
V
Q
K
I
K
A
I
----
K
E
V
-
A
--
P
--
S
L
Y
I
V
A
R
T
D
A
R
G
V
E
G
L
D
E
A
I
E
R
A
N
A
Y
V
K
A
G
A
D
A
I
F
P
E
A
L
Q
S
-
E
E
E
F
R
L
F
N
S
K
V
N
A
P
L
L
A
N
M
T
E
F
G
K
T
P
Y
Y
S
A
E
-
E
F
A
N
M
G
F
Q
M
V
I
Y
P
V
T
S
L
R
V
A
A
K
A
Y
E
N
V
F
T
L
I
K
E
T
G
S
Q
K
D
A
L
S
N
M
Q
T
R
S
E
L
Y
E
T
I
---
S
Y
H
D
F
-
E
E
L
D
T
G
I
A
K
T
-----
109
HHSearch
76.13
44%
-43
- C4 -
3EOO
-
?
A:
[6-294]
----------
L
I
S
A
G
A
K
F
R
A
A
V
A
A
E
Q
-
P
L
Q
V
V
G
A
I
T
A
Y
A
A
K
M
A
E
A
V
G
F
K
A
V
Y
L
S
G
G
-
G
V
A
A
-
N
S
L
-
G
I
P
D
L
G
I
S
T
M
D
D
V
L
V
D
A
N
R
I
T
N
A
-
T
-
N
L
---
P
L
L
V
D
I
D
T
G
W
G
G
-
A
F
N
I
A
R
T
I
R
S
F
I
K
A
G
V
G
A
V
H
L
E
D
Q
V
G
Q
K
R
C
G
H
R
P
G
K
E
C
V
P
A
G
E
M
V
D
R
I
K
A
A
----
V
D
A
R
T
D-
E
--
T
F
V
I
M
A
R
T
D
A
A
A
A
E
G
I
D
A
A
I
E
R
A
I
A
Y
V
E
A
G
A
D
M
I
F
P
E
A
M
K
T
-
L
D
D
Y
R
R
F
K
E
A
V
K
V
P
I
L
A
N
L
T
E
F
G
S
T
P
L
F
T
L
D
-
E
L
K
G
A
N
V
D
I
A
L
Y
C
C
G
A
Y
R
A
M
N
K
A
A
L
N
F
Y
E
T
V
R
R
D
G
T
Q
K
A
A
V
P
T
M
Q
T
R
A
Q
L
Y
D
Y
L
---
G
Y
Y
A
Y
-
E
E
K
L
D
Q
L
F
N
Q
-----
9
PsiBlast_PDB
75.50
45%
-41
- C4 -
3EOO
-
?
A:
[12-285]
----------------
K
F
R
A
A
V
A
A
E
Q
-
P
L
Q
V
V
G
A
I
T
A
Y
A
A
K
M
A
E
A
V
G
F
K
A
V
Y
L
S
G
G
-
G
V
A
A
N
S
-
L
-
G
I
P
D
L
G
I
S
T
M
D
D
V
L
V
D
A
N
R
I
T
N
A
-
T
-
N
L
---
P
L
L
V
D
I
D
T
G
W
G
G
-
A
F
N
I
A
R
T
I
R
S
F
I
K
A
G
V
G
A
V
H
L
E
D
Q
V
G
Q
K
R
C
G
H
R
P
G
K
E
C
V
P
A
G
E
M
V
D
R
I
K
A
A
----
V
D
A
-
R
--
T
DE
T
F
V
I
M
A
R
T
D
A
A
A
A
E
G
I
D
A
A
I
E
R
A
I
A
Y
V
E
A
G
A
D
M
I
F
P
E
A
M
K
T
-
L
D
D
Y
R
R
F
K
E
A
V
K
V
P
I
L
A
N
L
T
E
F
G
S
T
P
L
F
T
L
D
-
E
L
K
G
A
N
V
D
I
A
L
Y
C
C
G
A
Y
R
A
M
N
K
A
A
L
N
F
Y
E
T
V
R
R
D
G
T
Q
K
A
A
V
P
T
M
Q
T
R
A
Q
L
Y
D
Y
L
---
G
Y
Y
A
Y
-
E
--------------
21
PsiBlast_CBE
70.86
44%
-12
- C4 -
1MUM
1
PRPB_ECOLI
B:
[9-290]
-----------------
F
R
A
A
L
T
K
E
N
-
P
L
Q
I
V
G
T
I
N
A
N
H
A
L
L
A
Q
R
A
G
Y
Q
A
I
Y
L
S
G
G
-
G
V
A
A
G
S
-
L
-
G
L
P
D
L
G
I
S
T
L
D
D
V
L
T
D
I
R
R
I
T
D
V
-
C
-
S
L
---
P
L
L
V
D
A
D
I
G
F
G
S
S
A
F
N
V
A
R
T
V
K
S
M
I
K
A
G
A
A
G
L
H
I
E
D
Q
V
G
A
K
R
C
G
H
R
P
N
K
A
I
V
S
K
E
E
M
V
D
R
I
R
A
A
----
V
D
A
-
K
TD
P
--
D
F
V
I
M
A
R
T
D
A
L
A
V
E
G
L
D
A
A
I
E
R
A
Q
A
Y
V
E
A
G
A
E
M
L
F
P
E
A
I
T
E
-
L
A
M
Y
R
Q
F
A
D
A
V
Q
V
P
I
L
A
N
I
T
E
F
G
A
T
P
L
F
T
T
D
-
E
L
R
S
A
H
V
A
M
A
L
Y
P
L
S
A
F
R
A
M
N
R
A
A
E
H
V
Y
N
V
L
R
Q
E
G
T
Q
K
S
V
I
D
T
M
Q
T
R
N
E
L
Y
E
S
I
---
N
Y
Y
Q
Y
E
E
K
L
D
N
L
F
A
-------
103
HHSearch
70.43
43%
-15
- C4 -
1XG4
3
PRPB_ECOLI
A:
[2-287]
----------
L
H
S
P
G
K
A
F
R
A
A
L
T
K
E
N
-
P
L
Q
I
V
G
T
I
N
A
N
H
A
L
L
A
Q
R
A
G
Y
Q
A
I
Y
L
S
G
G
-
G
V
A
A
G
S
-
L
-
G
L
P
D
L
G
I
S
T
L
D
D
V
L
T
D
I
R
R
I
T
D
V
-
C
-
S
L
---
P
L
L
V
D
A
D
I
G
F
G
S
S
A
F
N
V
A
R
T
V
K
S
M
I
K
A
G
A
A
G
L
H
I
E
D
Q
V
G
A
K
R
S
G
H
R
P
N
K
A
I
V
S
K
E
E
M
V
D
R
I
R
A
A
----
V
D
A
K
T
D-
P
--
D
F
V
I
M
A
R
T
D
A
L
A
V
E
G
L
D
A
A
I
E
R
A
Q
A
Y
V
E
A
G
A
E
M
L
F
P
E
A
I
T
E
-
L
A
M
Y
R
Q
F
A
D
A
V
Q
V
P
I
L
A
N
I
T
E
F
G
A
T
P
L
F
T
T
D
-
E
L
R
S
A
H
V
A
M
A
L
Y
P
L
S
A
F
R
A
M
N
R
A
A
E
H
V
Y
N
V
L
R
Q
E
G
T
Q
K
S
V
I
D
T
M
Q
T
R
N
E
L
Y
E
S
I
---
N
Y
Y
Q
Y
-
E
E
K
L
D
N
---------
8
PsiBlast_PDB
69.83
43%
-12
- C4 -
1O5Q
2
PRPB_SALTY
A:
[12-285]
-----------------
F
R
A
A
L
A
K
E
N
-
P
L
Q
I
V
G
A
I
N
A
N
H
A
L
L
A
Q
R
A
G
Y
Q
A
I
Y
L
S
G
G
-
G
V
A
A
G
S
-
L
-
G
L
P
D
L
G
I
S
T
L
D
D
V
L
T
D
I
R
R
I
T
D
V
-
C
-
P
L
---
P
L
L
V
D
A
D
I
G
F
G
S
S
A
F
N
V
A
R
T
V
K
S
I
A
K
A
G
A
A
A
L
H
I
E
D
Q
V
-----------
A
I
V
S
K
E
E
M
V
D
R
I
R
A
A
----
V
D
A
-
R
TD
P
--
N
F
V
I
M
A
R
T
D
A
L
A
V
E
G
L
E
A
A
L
D
R
A
Q
A
Y
V
D
A
G
A
D
M
L
F
P
E
A
I
T
E
-
L
S
M
Y
R
R
F
A
D
V
A
Q
V
P
I
L
A
N
I
T
E
F
G
A
T
P
L
F
T
T
D
-
E
L
R
S
A
H
V
A
M
A
L
Y
P
L
S
A
F
R
A
M
N
R
A
A
E
K
V
Y
T
V
L
R
Q
E
G
T
Q
K
N
V
I
D
I
M
Q
T
R
N
E
L
Y
E
S
I
---
N
Y
Y
Q
F
-
E
--------------
3
PsiBlast_PDB
69.78
44%
-12
- C4 -
1MUM
1
PRPB_ECOLI
A:
[9-290]
-----------------
F
R
A
A
L
T
K
E
N
-
P
L
Q
I
V
G
T
I
N
A
N
H
A
L
L
A
Q
R
A
G
Y
Q
A
I
Y
L
S
G
G
-
G
V
A
A
G
S
-
L
-
G
L
P
D
L
G
I
S
T
L
D
D
V
L
T
D
I
R
R
I
T
D
V
-
C
-
S
L
---
P
L
L
V
D
A
D
I
G
F
G
S
S
A
F
N
V
A
R
T
V
K
S
M
I
K
A
G
A
A
G
L
H
I
E
D
Q
V
G
A
K
R
C
G
H
R
P
N
K
A
I
V
S
K
E
E
M
V
D
R
I
R
A
A
----
V
D
A
-
K
TD
P
--
D
F
V
I
M
A
R
T
D
A
L
A
V
E
G
L
D
A
A
I
E
R
A
Q
A
Y
V
E
A
G
A
E
M
L
F
P
E
A
I
T
E
-
L
A
M
Y
R
Q
F
A
D
A
V
Q
V
P
I
L
A
N
I
T
E
F
G
A
T
P
L
F
T
T
D
-
E
L
R
S
A
H
V
A
M
A
L
Y
P
L
S
A
F
R
A
M
N
R
A
A
E
H
V
Y
N
V
L
R
Q
E
G
T
Q
K
S
V
I
D
T
M
Q
T
R
N
E
L
Y
E
S
I
---
N
Y
Y
Q
Y
E
E
K
L
D
N
L
F
A
-------
24
PsiBlast_CBE
69.77
44%
-11
- C4 -
1XG4
3
PRPB_ECOLI
B:
[9-287]
-----------------
F
R
A
A
L
T
K
E
N
-
P
L
Q
I
V
G
T
I
N
A
N
H
A
L
L
A
Q
R
A
G
Y
Q
A
I
Y
L
S
G
G
-
G
V
A
A
G
S
-
L
-
G
L
P
D
L
G
I
S
T
L
D
D
V
L
T
D
I
R
R
I
T
D
V
-
C
-
S
L
---
P
L
L
V
D
A
D
I
G
F
G
S
S
A
F
N
V
A
R
T
V
K
S
M
I
K
A
G
A
A
G
L
H
I
E
D
Q
V
G
A
K
R
S
G
H
R
P
N
K
A
I
V
S
K
E
E
M
V
D
R
I
R
A
A
----
V
D
A
-
K
TD
P
--
D
F
V
I
M
A
R
T
D
A
L
A
V
E
G
L
D
A
A
I
E
R
A
Q
A
Y
V
E
A
G
A
E
M
L
F
P
E
A
I
T
E
-
L
A
M
Y
R
Q
F
A
D
A
V
Q
V
P
I
L
A
N
I
T
E
F
G
A
T
P
L
F
T
T
D
-
E
L
R
S
A
H
V
A
M
A
L
Y
P
L
S
A
F
R
A
M
N
R
A
A
E
H
V
Y
N
V
L
R
Q
E
G
T
Q
K
S
V
I
D
T
M
Q
T
R
N
E
L
Y
E
S
I
---
N
Y
Y
Q
Y
E
E
K
L
D
N
----------
25
PsiBlast_CBE
69.30
44%
-11
- C4 -
1XG3
3
PRPB_ECOLI
D:
[9-284]
-----------------
F
R
A
A
L
T
K
E
N
-
P
L
Q
I
V
G
T
I
N
A
N
H
A
L
L
A
Q
R
A
G
Y
Q
A
I
Y
L
S
G
G
-
G
V
A
A
G
S
-
L
-
G
L
P
D
L
G
I
S
T
L
D
D
V
L
T
D
I
R
R
I
T
D
V
-
C
-
S
L
---
P
L
L
V
D
A
D
I
G
F
G
S
S
A
F
N
V
A
R
T
V
K
S
M
I
K
A
G
A
A
G
L
H
I
E
D
Q
V
G
A
K
R
S
G
H
R
P
N
K
A
I
V
S
K
E
E
M
V
D
R
I
R
A
A
----
V
D
A
-
K
TD
P
--
D
F
V
I
M
A
R
T
D
A
L
A
V
E
G
L
D
A
A
I
E
R
A
Q
A
Y
V
E
A
G
A
E
M
L
F
P
E
A
I
T
E
-
L
A
M
Y
R
Q
F
A
D
A
V
Q
V
P
I
L
A
N
I
T
E
F
G
A
T
P
L
F
T
T
D
-
E
L
R
S
A
H
V
A
M
A
L
Y
P
L
S
A
F
R
A
M
N
R
A
A
E
H
V
Y
N
V
L
R
Q
E
G
T
Q
K
S
V
I
D
T
M
Q
T
R
N
E
L
Y
E
S
I
---
N
Y
Y
Q
Y
E
E
K
-------------
29
PsiBlast_CBE
69.24
43%
-16
- C4 -
1O5Q
2
PRPB_SALTY
C:
[12-285]
-----------------
F
R
A
A
L
A
K
E
N
-
P
L
Q
I
V
G
A
I
N
A
N
H
A
L
L
A
Q
R
A
G
Y
Q
A
I
Y
L
S
G
G
-
G
V
A
A
G
S
-
L
-
G
L
P
D
L
G
I
S
T
L
D
D
V
L
T
D
I
R
R
I
T
D
V
-
C
-
P
L
---
P
L
L
V
D
A
D
I
G
F
G
S
S
A
F
N
V
A
R
T
V
K
S
I
A
K
A
G
A
A
A
L
H
I
E
D
Q
V
-----------
A
I
V
S
K
E
E
M
V
D
R
I
R
A
A
----
V
D
A
-
R
TD
P
--
N
F
V
I
M
A
R
T
D
A
L
A
V
E
G
L
E
A
A
L
D
R
A
Q
A
Y
V
D
A
G
A
D
M
L
F
P
E
A
I
T
E
-
L
S
M
Y
R
R
F
A
D
V
A
Q
V
P
I
L
A
N
I
T
E
F
G
A
T
P
L
F
T
T
D
-
E
L
R
S
A
H
V
A
M
A
L
Y
P
L
S
A
F
R
A
M
N
R
A
A
E
K
V
Y
T
V
L
R
Q
E
G
T
Q
K
N
V
I
D
I
M
Q
T
R
N
E
L
Y
E
S
I
---
N
Y
Y
Q
F
-
E
--------------
27
PsiBlast_CBE
69.10
44%
-10
- C4 -
1XG3
4
PRPB_ECOLI
B:
[9-287]
-----------------
F
R
A
A
L
T
K
E
N
-
P
L
Q
I
V
G
T
I
N
A
N
H
A
L
L
A
Q
R
A
G
Y
Q
A
I
Y
L
S
G
G
-
G
V
A
A
G
S
-
L
-
G
L
P
D
L
G
I
S
T
L
D
D
V
L
T
D
I
R
R
I
T
D
V
-
C
-
S
L
---
P
L
L
V
D
A
D
I
G
F
G
S
S
A
F
N
V
A
R
T
V
K
S
M
I
K
A
G
A
A
G
L
H
I
E
D
Q
V
G
A
K
R
S
G
H
R
P
N
K
A
I
V
S
K
E
E
M
V
D
R
I
R
A
A
----
V
D
A
-
K
TD
P
--
D
F
V
I
M
A
R
T
D
A
L
A
V
E
G
L
D
A
A
I
E
R
A
Q
A
Y
V
E
A
G
A
E
M
L
F
P
E
A
I
T
E
-
L
A
M
Y
R
Q
F
A
D
A
V
Q
V
P
I
L
A
N
I
T
E
F
G
A
T
P
L
F
T
T
D
-
E
L
R
S
A
H
V
A
M
A
L
Y
P
L
S
A
F
R
A
M
N
R
A
A
E
H
V
Y
N
V
L
R
Q
E
G
T
Q
K
S
V
I
D
T
M
Q
T
R
N
E
L
Y
E
S
I
---
N
Y
Y
Q
Y
E
E
K
L
D
N
----------
28
PsiBlast_CBE
68.94
43%
-17
- C4 -
1O5Q
2
PRPB_SALTY
D:
[12-284]
-----------------
F
R
A
A
L
A
K
E
N
-
P
L
Q
I
V
G
A
I
N
A
N
H
A
L
L
A
Q
R
A
G
Y
Q
A
I
Y
L
S
G
G
-
G
V
A
A
G
S
-
L
-
G
L
P
D
L
G
I
S
T
L
D
D
V
L
T
D
I
R
R
I
T
D
V
-
C
-
P
L
---
P
L
L
V
D
A
D
I
G
F
G
S
S
A
F
N
V
A
R
T
V
K
S
I
A
K
A
G
A
A
A
L
H
I
E
D
Q
V
-----------
A
I
V
S
K
E
E
M
V
D
R
I
R
A
A
----
V
D
A
-
R
TD
P
--
N
F
V
I
M
A
R
T
D
A
L
A
V
E
G
L
E
A
A
L
D
R
A
Q
A
Y
V
D
A
G
A
D
M
L
F
P
E
A
I
T
E
-
L
S
M
Y
R
R
F
A
D
V
A
Q
V
P
I
L
A
N
I
T
E
F
G
A
T
P
L
F
T
T
D
-
E
L
R
S
A
H
V
A
M
A
L
Y
P
L
S
A
F
R
A
M
N
R
A
A
E
K
V
Y
T
V
L
R
Q
E
G
T
Q
K
N
V
I
D
I
M
Q
T
R
N
E
L
Y
E
S
I
---
N
Y
Y
Q
F
----------------
6
PsiBlast_PDB
68.85
44%
-14
- C4 -
1XG4
3
PRPB_ECOLI
A:
[9-287]
-----------------
F
R
A
A
L
T
K
E
N
-
P
L
Q
I
V
G
T
I
N
A
N
H
A
L
L
A
Q
R
A
G
Y
Q
A
I
Y
L
S
G
G
-
G
V
A
A
G
S
-
L
-
G
L
P
D
L
G
I
S
T
L
D
D
V
L
T
D
I
R
R
I
T
D
V
-
C
-
S
L
---
P
L
L
V
D
A
D
I
G
F
G
S
S
A
F
N
V
A
R
T
V
K
S
M
I
K
A
G
A
A
G
L
H
I
E
D
Q
V
G
A
K
R
S
G
H
R
P
N
K
A
I
V
S
K
E
E
M
V
D
R
I
R
A
A
----
V
D
A
-
K
TD
P
--
D
F
V
I
M
A
R
T
D
A
L
A
V
E
G
L
D
A
A
I
E
R
A
Q
A
Y
V
E
A
G
A
E
M
L
F
P
E
A
I
T
E
-
L
A
M
Y
R
Q
F
A
D
A
V
Q
V
P
I
L
A
N
I
T
E
F
G
A
T
P
L
F
T
T
D
-
E
L
R
S
A
H
V
A
M
A
L
Y
P
L
S
A
F
R
A
M
N
R
A
A
E
H
V
Y
N
V
L
R
Q
E
G
T
Q
K
S
V
I
D
T
M
Q
T
R
N
E
L
Y
E
S
I
---
N
Y
Y
Q
Y
E
E
K
L
D
N
----------
4
PsiBlast_PDB
68.67
44%
-8
- C4 -
1OQF
-
PRPB_ECOLI
A:
[9-290]
-----------------
F
R
A
A
L
T
K
E
N
-
P
L
Q
I
V
G
T
I
N
A
N
H
A
L
L
A
Q
R
A
G
Y
Q
A
I
Y
L
S
G
G
-
G
V
A
A
G
S
-
L
-
G
L
P
D
L
G
I
S
T
L
D
D
V
L
T
D
I
R
R
I
T
D
V
-
C
-
S
L
---
P
L
L
V
D
A
D
I
G
F
G
S
S
A
F
N
V
A
R
T
V
K
S
M
I
K
A
G
A
A
G
L
H
I
E
D
Q
V
G
A
K
R
C
G
H
R
P
N
K
A
I
V
S
K
E
E
M
V
D
R
I
R
A
A
----
V
D
A
-
K
TD
P
--
D
F
V
I
M
A
R
T
D
A
L
A
V
E
G
L
D
A
A
I
E
R
A
Q
A
Y
V
E
A
G
A
E
M
L
F
P
E
A
I
T
E
-
L
A
M
Y
R
Q
F
A
D
A
V
Q
V
P
I
L
A
N
I
T
E
F
G
A
T
P
L
F
T
T
D
-
E
L
R
S
A
H
V
A
M
A
L
Y
P
L
S
A
F
R
A
M
N
R
A
A
E
H
V
Y
N
V
L
R
Q
E
G
T
Q
K
S
V
I
D
T
M
Q
T
R
N
E
L
Y
E
S
I
---
N
Y
Y
Q
Y
E
E
K
L
D
N
L
F
A
-------
63
PsiBlast_CBE
68.65
32%
-47
- C4 -
3B8I
3
OADC_PSEAE
F:
[3-244]
-------
R
A
S
H
H
E
L
R
A
M
F
R
A
L
L
D
S
S
R
-
C
Y
H
T
A
S
V
F
D
P
M
S
A
R
I
A
A
D
L
G
F
E
C
G
I
L
G
G
S
V
A
S
L
Q
-
V
-
L
-
A
A
P
D
F
A
L
I
T
L
S
E
F
V
E
Q
A
T
R
I
G
R
V
-
A
-
R
L
---
P
V
I
A
D
A
D
H
G
Y
G
N
-
A
L
N
V
M
R
T
V
V
E
L
E
R
A
G
I
A
A
L
T
I
E
D
T
L
L
P
A
Q
F
G
R
-
K
S
T
D
L
I
C
V
E
E
G
V
G
K
I
R
A
A
----
L
E
A
-
R
VD
P
--
A
L
T
I
I
A
R
T
N
A
E
L
I
D
-
V
D
A
V
I
Q
R
T
L
A
Y
Q
E
A
G
A
D
G
I
C
L
V
G
V
R
D
-
F
A
H
L
E
A
I
A
E
H
L
H
I
P
L
M
--
L
V
T
Y
G
N
-
P
Q
L
R
D
D
A
R
L
A
R
L
G
V
R
V
V
V
N
G
H
A
A
Y
F
A
A
I
K
A
-------------------------------------------------------
65
PsiBlast_CBE
68.62
32%
-50
- C4 -
3B8I
4
OADC_PSEAE
C:
[3-248]
-------
R
A
S
H
H
E
L
R
A
M
F
R
A
L
L
D
S
S
R
-
C
Y
H
T
A
S
V
F
D
P
M
S
A
R
I
A
A
D
L
G
F
E
C
G
I
L
G
G
S
V
A
S
L
Q
-
V
-
L
-
A
A
P
D
F
A
L
I
T
L
S
E
F
V
E
Q
A
T
R
I
G
R
V
-
A
-
R
L
---
P
V
I
A
D
A
D
H
G
Y
G
N
-
A
L
N
V
M
R
T
V
V
E
L
E
R
A
G
I
A
A
L
T
I
E
D
T
L
L
P
A
Q
F
G
R
-
K
S
T
D
L
I
C
V
E
E
G
V
G
K
I
R
A
A
----
L
E
A
-
R
VD
P
--
A
L
T
I
I
A
R
T
N
A
E
L
I
D
-
V
D
A
V
I
Q
R
T
L
A
Y
Q
E
A
G
A
D
G
I
C
L
V
G
V
R
D
-
F
A
H
L
E
A
I
A
E
H
L
H
I
P
L
M
--
L
V
T
Y
G
N
-
P
Q
L
R
D
D
A
R
L
A
R
L
G
V
R
V
V
V
N
G
H
A
A
Y
F
A
A
I
K
A
-------------------------------------------------------
30
PsiBlast_CBE
68.41
43%
-14
- C4 -
1O5Q
2
PRPB_SALTY
B:
[12-285]
-----------------
F
R
A
A
L
A
K
E
N
-
P
L
Q
I
V
G
A
I
N
A
N
H
A
L
L
A
Q
R
A
G
Y
Q
A
I
Y
L
S
G
G
-
G
V
A
A
G
S
-
L
-
G
L
P
D
L
G
I
S
T
L
D
D
V
L
T
D
I
R
R
I
T
D
V
-
C
-
P
L
---
P
L
L
V
D
A
D
I
G
F
G
S
S
A
F
N
V
A
R
T
V
K
S
I
A
K
A
G
A
A
A
L
H
I
E
D
Q
V
-----------
A
I
V
S
K
E
E
M
V
D
R
I
R
A
A
----
V
D
A
-
R
TD
P
--
N
F
V
I
M
A
R
T
D
A
L
A
V
E
G
L
E
A
A
L
D
R
A
Q
A
Y
V
D
A
G
A
D
M
L
F
P
E
A
I
T
E
-
L
S
M
Y
R
R
F
A
D
V
A
Q
V
P
I
L
A
N
I
T
E
F
G
A
T
P
L
F
T
T
D
-
E
L
R
S
A
H
V
A
M
A
L
Y
P
L
S
A
F
R
A
M
N
R
A
A
E
K
V
Y
T
V
L
R
Q
E
G
T
Q
K
N
V
I
D
I
M
Q
T
R
N
E
L
Y
E
S
I
---
N
Y
Y
Q
F
-
E
--------------
22
PsiBlast_CBE
68.24
44%
-11
- C4 -
1XG4
2
PRPB_ECOLI
D:
[9-284]
-----------------
F
R
A
A
L
T
K
E
N
-
P
L
Q
I
V
G
T
I
N
A
N
H
A
L
L
A
Q
R
A
G
Y
Q
A
I
Y
L
S
G
G
-
G
V
A
A
G
S
-
L
-
G
L
P
D
L
G
I
S
T
L
D
D
V
L
T
D
I
R
R
I
T
D
V
-
C
-
S
L
---
P
L
L
V
D
A
D
I
G
F
G
S
S
A
F
N
V
A
R
T
V
K
S
M
I
K
A
G
A
A
G
L
H
I
E
D
Q
V
G
A
K
R
S
G
H
R
P
N
K
A
I
V
S
K
E
E
M
V
D
R
I
R
A
A
----
V
D
A
-
K
TD
P
--
D
F
V
I
M
A
R
T
D
A
L
A
V
E
G
L
D
A
A
I
E
R
A
Q
A
Y
V
E
A
G
A
E
M
L
F
P
E
A
I
T
E
-
L
A
M
Y
R
Q
F
A
D
A
V
Q
V
P
I
L
A
N
I
T
E
F
G
A
T
P
L
F
T
T
D
-
E
L
R
S
A
H
V
A
M
A
L
Y
P
L
S
A
F
R
A
M
N
R
A
A
E
H
V
Y
N
V
L
R
Q
E
G
T
Q
K
S
V
I
D
T
M
Q
T
R
N
E
L
Y
E
S
I
---
N
Y
Y
Q
Y
E
E
K
-------------
5
PsiBlast_PDB
68.00
44%
-10
- C4 -
1XG3
4
PRPB_ECOLI
A:
[9-288]
-----------------
F
R
A
A
L
T
K
E
N
-
P
L
Q
I
V
G
T
I
N
A
N
H
A
L
L
A
Q
R
A
G
Y
Q
A
I
Y
L
S
G
G
-
G
V
A
A
G
S
-
L
-
G
L
P
D
L
G
I
S
T
L
D
D
V
L
T
D
I
R
R
I
T
D
V
-
C
-
S
L
---
P
L
L
V
D
A
D
I
G
F
G
S
S
A
F
N
V
A
R
T
V
K
S
M
I
K
A
G
A
A
G
L
H
I
E
D
Q
V
G
A
K
R
S
G
H
R
P
N
K
A
I
V
S
K
E
E
M
V
D
R
I
R
A
A
----
V
D
A
-
K
TD
P
--
D
F
V
I
M
A
R
T
D
A
L
A
V
E
G
L
D
A
A
I
E
R
A
Q
A
Y
V
E
A
G
A
E
M
L
F
P
E
A
I
T
E
-
L
A
M
Y
R
Q
F
A
D
A
V
Q
V
P
I
L
A
N
I
T
E
F
G
A
T
P
L
F
T
T
D
-
E
L
R
S
A
H
V
A
M
A
L
Y
P
L
S
A
F
R
A
M
N
R
A
A
E
H
V
Y
N
V
L
R
Q
E
G
T
Q
K
S
V
I
D
T
M
Q
T
R
N
E
L
Y
E
S
I
---
N
Y
Y
Q
Y
E
E
K
L
D
N
L
---------
26
PsiBlast_CBE
66.92
44%
-9
- C4 -
1XG3
3
PRPB_ECOLI
C:
[9-288]
-----------------
F
R
A
A
L
T
K
E
N
-
P
L
Q
I
V
G
T
I
N
A
N
H
A
L
L
A
Q
R
A
G
Y
Q
A
I
Y
L
S
G
G
-
G
V
A
A
G
S
-
L
-
G
L
P
D
L
G
I
S
T
L
D
D
V
L
T
D
I
R
R
I
T
D
V
-
C
-
S
L
---
P
L
L
V
D
A
D
I
G
F
G
S
S
A
F
N
V
A
R
T
V
K
S
M
I
K
A
G
A
A
G
L
H
I
E
D
Q
V
G
A
K
R
S
G
H
R
P
N
K
A
I
V
S
K
E
E
M
V
D
R
I
R
A
A
----
V
D
A
-
K
TD
P
--
D
F
V
I
M
A
R
T
D
A
L
A
V
E
G
L
D
A
A
I
E
R
A
Q
A
Y
V
E
A
G
A
E
M
L
F
P
E
A
I
T
E
-
L
A
M
Y
R
Q
F
A
D
A
V
Q
V
P
I
L
A
N
I
T
E
F
G
A
T
P
L
F
T
T
D
-
E
L
R
S
A
H
V
A
M
A
L
Y
P
L
S
A
F
R
A
M
N
R
A
A
E
H
V
Y
N
V
L
R
Q
E
G
T
Q
K
S
V
I
D
T
M
Q
T
R
N
E
L
Y
E
S
I
---
N
Y
Y
Q
Y
E
E
K
L
D
N
L
---------
85
Fugue
66.23
37%
8
- C4 -
1ZLP
2
PDP_DIACA
A:
[28-311]
--------------
K
T
T
M
H
R
L
I
E
E
H
G
-
S
V
L
M
P
G
V
Q
D
A
L
S
A
A
V
V
E
K
T
G
F
H
A
A
F
V
S
G
Y
-
S
V
S
A
-
A
-
M
L
G
L
P
D
F
G
L
L
T
T
T
E
V
V
E
A
T
R
R
I
T
A
A
-
A
P
N
L
---
C
V
V
V
D
G
D
T
G
G
G
G
-
P
L
N
V
Q
R
F
I
R
E
L
I
S
A
G
A
K
G
V
F
L
E
D
Q
V
W
P
K
K
C
G
H
M
R
G
K
A
V
V
P
A
E
E
H
A
L
K
I
A
A
A
----
R
E
A
-
I
GD
S
--
D
F
F
L
V
A
R
T
D
A
R
A
P
H
G
L
E
E
G
I
R
R
A
N
L
Y
K
E
A
G
A
D
A
T
F
V
E
A
P
A
N
-
V
D
E
L
K
E
V
S
A
K
T
K
G
L
R
I
A
N
M
I
E
G
G
K
T
P
L
H
T
P
E
-
E
F
K
E
M
G
F
H
L
I
A
H
S
L
T
A
V
Y
A
T
A
R
A
L
V
N
I
M
K
I
L
K
E
K
G
T
T
R
D
D
L
D
Q
M
A
T
F
S
E
F
N
E
L
I
---
S
L
E
S
W
-
Y
E
M
E
S
K
F
K
-------
95
HHSearch
65.61
36%
9
- C4 -
1ZLP
2
PDP_DIACA
A:
[28-311]
--------------
K
T
T
M
H
R
L
I
E
E
H
G
-
S
V
L
M
P
G
V
Q
D
A
L
S
A
A
V
V
E
K
T
G
F
H
A
A
F
V
S
G
Y
-
S
V
S
A
-
A
M
L
-
G
L
P
D
F
G
L
L
T
T
T
E
V
V
E
A
T
R
R
I
T
A
A
A
P
-
N
L
---
C
V
V
V
D
G
D
T
G
G
G
G
-
P
L
N
V
Q
R
F
I
R
E
L
I
S
A
G
A
K
G
V
F
L
E
D
Q
V
W
P
K
K
C
G
H
M
R
G
K
A
V
V
P
A
E
E
H
A
L
K
I
A
A
A
----
R
E
A
I
G
D-
S
--
D
F
F
L
V
A
R
T
D
A
R
A
P
H
G
L
E
E
G
I
R
R
A
N
L
Y
K
E
A
G
A
D
A
T
F
V
E
A
P
A
N
-
V
D
E
L
K
E
V
S
A
K
T
K
G
L
R
I
A
N
M
I
E
G
G
K
T
P
L
H
T
P
E
-
E
F
K
E
M
G
F
H
L
I
A
H
S
L
T
A
V
Y
A
T
A
R
A
L
V
N
I
M
K
I
L
K
E
K
G
T
T
R
D
D
L
D
Q
M
A
T
F
S
E
F
N
E
L
I
---
S
L
E
S
W
-
Y
E
M
E
S
K
F
K
-------
31
PsiBlast_CBE
60.63
39%
10
- C4 -
1ZLP
2
PDP_DIACA
B:
[43-308]
------------------------------
M
P
G
V
Q
D
A
L
S
A
A
V
V
E
K
T
G
F
H
A
A
F
V
S
G
Y
-
S
V
S
A
-
A
-
M
L
G
L
P
D
F
G
L
L
T
T
T
E
V
V
E
A
T
R
R
I
T
A
A
-
A
P
N
L
---
C
V
V
V
D
G
D
T
G
G
G
G
-
P
L
N
V
Q
R
F
I
R
E
L
I
S
A
G
A
K
G
V
F
L
E
D
Q
V
W
P
K
K
C
G
H
M
R
G
K
A
V
V
P
A
E
E
H
A
L
K
I
A
A
A
----
R
E
A
-
I
GD
S
--
D
F
F
L
V
A
R
T
D
A
R
A
P
H
G
L
E
E
G
I
R
R
A
N
L
Y
K
E
A
G
A
D
A
T
F
V
E
A
P
A
N
-
V
D
E
L
K
E
V
S
A
K
T
K
G
L
R
I
A
N
M
I
E
G
G
K
T
P
L
H
T
P
E
-
E
F
K
E
M
G
F
H
L
I
A
H
S
L
T
A
V
Y
A
T
A
R
A
L
V
N
I
M
K
I
L
K
E
K
G
T
T
R
D
D
L
D
Q
M
A
T
F
S
E
F
N
E
L
I
SLE
S
W
Y
E
M
-
E
S
-------------
14
PsiBlast_PDB
59.68
33%
9
- C4 -
3M0J
3
?
A:
[13-296]
--------------
A
K
K
L
R
H
L
L
E
N
T
D
E
L
I
V
C
P
G
V
Y
D
G
L
S
A
R
T
A
M
E
L
G
F
K
S
L
Y
M
T
G
A
-
G
T
T
A
-
S
-
R
L
G
Q
P
D
L
A
I
A
Q
L
H
D
M
R
D
N
A
-
D
M
I
A
N
-
L
-
D
P
F
G
P
P
L
I
A
D
M
D
T
G
Y
G
G
-
P
I
M
V
A
R
T
V
E
H
Y
I
R
S
G
V
A
G
A
H
L
E
D
Q
I
L
T
K
R
C
G
H
L
S
G
K
K
V
V
S
R
D
E
Y
L
V
R
I
R
A
A
V
A
T
K
R
R
L
-
R
--
S
--
D
F
V
L
I
A
R
T
D
A
L
Q
S
L
G
Y
E
E
C
I
E
R
L
R
A
A
R
D
E
G
A
D
V
G
L
L
E
G
F
R
S
K
E
Q
A
A
A
A
V
A
A
L
A
P
W
P
L
L
L
N
S
V
E
N
G
H
S
P
L
I
T
V
E
-
E
A
K
A
M
G
F
R
I
M
I
F
S
F
A
T
L
A
P
A
Y
A
A
I
R
E
T
L
V
R
L
R
D
H
G
V
V
--
G
T
P
D
G
I
T
P
V
R
L
F
E
V
C
---
G
L
Q
D
A
-
M
E
V
D
N
----------
10
PsiBlast_PDB
59.23
39%
16
- C4 -
1ZLP
2
PDP_DIACA
A:
[43-308]
------------------------------
M
P
G
V
Q
D
A
L
S
A
A
V
V
E
K
T
G
F
H
A
A
F
V
S
G
Y
-
S
V
S
A
-
A
-
M
L
G
L
P
D
F
G
L
L
T
T
T
E
V
V
E
A
T
R
R
I
T
A
A
-
A
P
N
L
---
C
V
V
V
D
G
D
T
G
G
G
G
-
P
L
N
V
Q
R
F
I
R
E
L
I
S
A
G
A
K
G
V
F
L
E
D
Q
V
W
P
K
K
C
G
H
M
R
G
K
A
V
V
P
A
E
E
H
A
L
K
I
A
A
A
----
R
E
A
-
I
GD
S
--
D
F
F
L
V
A
R
T
D
A
R
A
P
H
G
L
E
E
G
I
R
R
A
N
L
Y
K
E
A
G
A
D
A
T
F
V
E
A
P
A
N
-
V
D
E
L
K
E
V
S
A
K
T
K
G
L
R
I
A
N
M
I
E
G
G
K
T
P
L
H
T
P
E
-
E
F
K
E
M
G
F
H
L
I
A
H
S
L
T
A
V
Y
A
T
A
R
A
L
V
N
I
M
K
I
L
K
E
K
G
T
T
R
D
D
L
D
Q
M
A
T
F
S
E
F
N
E
L
I
S
L
E
S
W
Y
E
M
-
E
S
-------------