@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu24960: (2016-07-09 )
MSEQMVKEKPERAVIVPKQNHVLEVKDLSIYYGNKQAVHHVNMDIEKNAVTALIGPSGCGKSTFLRNINRMNDLIPSARAEGEILYEGLNILGGNINVVSLRREIGMVFQKPNPFPKSIYANITHALKYAGERNKAVLDEIVEESLTKAALWDEVKDRLHSSALSLSGGQQQRLCIARTLAMKPAVLLLDEPASALDPISNAKIEELITGLKREYSIIIVTHNMQQALRVSDRTAFFLNGELVEYGQTEQIFTSPKKQKTEDYINGKFG
Atome Classification :
(35 SA)
.........10........20......---..30.----.----.....---.40---........50........60.......-------.70........80........-------------.90..-....---..100--..----.-.....110----.-....-..120....----.--..130----.-.-......140-........150.......-160---........170.......180-.......190.......200.......210.-.--.--..--..220.......230.....-..240.......250.....-..260.......---------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MS
E
Q
M
V
K
EKPE
R
A
V
I
VPKQN
H
V
L
E
V
K
D
---
L
S
I
Y
Y----G----NK
Q
A
V
---
H
H
V---NMDIEKN
A
V
T
A
L
IGPSGC
G
K
S
T
F
L
R
N
I
-------
N
R
M
N
D
LIPSARA-E
G
E
I
L
Y
E
G
-------------
L
N
ILG-GN
I
N
---
V
V
S
L
---
R
R
----
E
-
I
G
M
VFQKP----N-PF
P
K
-
S
I
Y
A
N
I
T
H
A
----
L
--
K
YAG-----E-R-
N
K
A
V
L
D
E
I
--
V
E
E
S
L
T
K
A
A
L
W
D
E
V
K
D
R
L
-
H
S
----
S
ALSLSGGQQ
Q
R
L
C
I
A
R
TLAM-K
P
A
V
L
L
LDEP
A
S
ALDPIS
N
A
K
I
E
E
L
I
T
G
LKR-
E
--
Y
--
S
I
--
I
I
V
THN
M
Q
Q
A
L
RVSD
R
T
A
F
F
-LNG
E
L
VEYGQT
E
Q
I
FTSPKK-Q
K
T
E
D
YINGKFG---------------------------------------------------------------------------------------------
9
PsiBlast_PDB
86.24
38%
-49
- C1 -
4YMU
2
?
J:
[4-237]
------------------------
V
N
D
---
V
Y
K
N
F
----
G
----
S
L
E
V
L
---
K
G
V
---
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
-------
N
L
L
E
E
--
P
T
----
K
G
E
V
F
I
D
G
-------------
V
K
I
N
N
-
G
K
V
N
---
I
N
K
V
---
R
Q
----
K
-
V
G
M
V
F
Q
H
F
----
N
-
L
F
P
H
L
T
A
I
E
N
I
T
L
A
----
P
--
V
K
V
K
-----
K
-
M
-
N
K
K
E
A
E
E
L
--
A
V
D
L
L
A
K
V
G
L
L
D
K
-
K
D
Q
Y
--------
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
-
E
G-
M
--
T
M
--
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
-
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
-
E
R
T
R
E
F
L
S
-------------------------------------------------------------------------------------------------
44
PsiBlast_CBE
85.91
35%
0
- C- -
4FWI
3
?
B:
[4-267]
---------------------
I
I
R
V
E
D
---
L
R
A
V
Y
LVRE
G
----
T
I
K
A
A
---
D
G
I
---
S
L
D
I
L
E
N
S
V
T
A
I
V
G
E
S
A
S
G
K
S
T
I
I
E
A
M
-------
T
K
--
T
L
P
P
N
G
R
I
L
S
G
R
V
L
Y
K
G
-------------
K
D
L
L
---
T
M
R
---
E
E
E
L
---
R
K
IRWK
E
-
I
A
L
V
P
Q
A
A
QQSL
N
-
P
T
M
K
-
V
I
-
E
H
F
K
D
T
----
V
--
E
A
H
G
-----
V
-
R
W
S
H
S
E
L
I
E
K
--
A
S
E
K
L
R
M
V
R
L
N
P
E
A
V
--
L
-
N
S
----
Y
P
L
Q
L
S
G
G
M
K
Q
R
V
L
I
A
L
A
L
L
L
-
D
P
V
V
L
I
L
D
E
P
T
S
A
L
D
V
L
T
Q
A
H
I
I
Q
L
L
K
E
L
K
K
-
M
--
L
--
K
I
TL
I
F
V
T
H
D
I
A
V
A
A
E
L
A
D
K
V
A
V
I
-
Y
G
G
N
L
V
E
Y
N
S
T
F
Q
I
F
K
N
P
L
H
-
P
Y
T
R
G
L
I
N
S
------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
84.41
38%
-50
- C1 -
4YMW
-
?
J:
[4-237]
------------------------
V
N
D
---
V
Y
K
N
F
----
G
----
S
L
E
V
L
---
K
G
V
---
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
-------
N
L
L
E
E
--
P
T
----
K
G
E
V
F
I
D
G
-------------
V
K
I
N
N
-
G
K
V
N
---
I
N
K
V
---
R
Q
----
K
-
V
G
M
V
F
Q
H
F
----
N
-
L
F
P
H
L
T
A
I
E
N
I
T
L
A
----
P
--
V
K
V
K
-----
K
-
M
-
N
K
K
E
A
E
E
L
--
A
V
D
L
L
A
K
V
G
L
L
D
K
-
K
D
Q
Y
--------
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
-
E
G-
M
--
T
M
--
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
-
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
-
E
R
T
R
E
F
L
S
-------------------------------------------------------------------------------------------------
31
PsiBlast_CBE
84.38
38%
-49
- C1 -
4YMV
1
?
A:
[4-237]
------------------------
V
N
D
---
V
Y
K
N
F
----
G
----
S
L
E
V
L
---
K
G
V
---
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
-------
N
L
L
E
E
--
P
T
----
K
G
E
V
F
I
D
G
-------------
V
K
I
N
N
-
G
K
V
N
---
I
N
K
V
---
R
Q
----
K
-
V
G
M
V
F
Q
H
F
----
N
-
L
F
P
H
L
T
A
I
E
N
I
T
L
A
----
P
--
V
K
V
K
-----
K
-
M
-
N
K
K
E
A
E
E
L
--
A
V
D
L
L
A
K
V
G
L
L
D
K
-
K
D
Q
Y
--------
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
-
E
G-
M
--
T
M
--
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
-
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
-
E
R
T
R
E
F
L
S
-------------------------------------------------------------------------------------------------
32
PsiBlast_CBE
84.16
38%
-49
- C1 -
4YMU
2
?
A:
[4-237]
------------------------
V
N
D
---
V
Y
K
N
F
----
G
----
S
L
E
V
L
---
K
G
V
---
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
-------
N
L
L
E
E
--
P
T
----
K
G
E
V
F
I
D
G
-------------
V
K
I
N
N
-
G
K
V
N
---
I
N
K
V
---
R
Q
----
K
-
V
G
M
V
F
Q
H
F
----
N
-
L
F
P
H
L
T
A
I
E
N
I
T
L
A
----
P
--
V
K
V
K
-----
K
-
M
-
N
K
K
E
A
E
E
L
--
A
V
D
L
L
A
K
V
G
L
L
D
K
-
K
D
Q
Y
--------
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
-
E
G-
M
--
T
M
--
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
-
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
-
E
R
T
R
E
F
L
S
-------------------------------------------------------------------------------------------------
30
PsiBlast_CBE
83.99
37%
-23
- C1 -
3C41
3
?
K:
[2-242]
--------------------
Q
M
I
D
V
H
Q
---
L
K
K
S
F
----
G
----
S
L
E
V
L
---
K
G
I
---
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
-------
N
L
L
E
D
F
-----
D
-
E
G
E
I
I
I
D
G
-------------
I
N
L
K
A
-
K
D
T
N
---
L
N
K
V
---
R
E
----
E
-
V
G
M
V
F
Q
R
F
----
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
PMKV
R
--
K
W
P
R
-----
E
-
K
-
A
E
A
K
A
M
E
L
------
L
D
K
V
G
L
----
K
D
K
A
-
H
A
----
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G-
M
--
T
M
--
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
-
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
-
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
8
PsiBlast_PDB
83.39
38%
-47
- C1 -
4YMT
-
?
J:
[4-237]
------------------------
V
N
D
---
V
Y
K
N
F
----
G
----
S
L
E
V
L
---
K
G
V
---
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
-------
N
L
L
E
E
--
P
T
----
K
G
E
V
F
I
D
G
-------------
V
K
I
N
N
-
G
K
V
N
---
I
N
K
V
---
R
Q
----
K
-
V
G
M
V
F
Q
H
F
----
N
-
L
F
P
H
L
T
A
I
E
N
I
T
L
A
----
P
--
V
K
V
K
-----
K
-
M
-
N
K
K
E
A
E
E
L
--
A
V
D
L
L
A
K
V
G
L
L
D
K
-
K
D
Q
Y
--------
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
-
E
G-
M
--
T
M
--
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
-
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
-
E
R
T
R
E
F
L
S
-------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
83.26
38%
-48
- C1 -
4YMS
-
?
J:
[4-237]
------------------------
V
N
D
---
V
Y
K
N
F
----
G
----
S
L
E
V
L
---
K
G
V
---
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
-------
N
L
L
E
E
--
P
T
----
K
G
E
V
F
I
D
G
-------------
V
K
I
N
N
-
G
K
V
N
---
I
N
K
V
---
R
Q
----
K
-
V
G
M
V
F
Q
H
F
----
N
-
L
F
P
H
L
T
A
I
E
N
I
T
L
A
----
P
--
V
K
V
K
-----
K
-
M
-
N
K
K
E
A
E
E
L
--
A
V
D
L
L
A
K
V
G
L
L
D
K
-
K
D
Q
Y
--------
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
-
E
G-
M
--
T
M
--
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
-
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
-
E
R
T
R
E
F
L
S
-------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
82.18
37%
-18
- C1 -
3C41
3
?
J:
[2-242]
--------------------
Q
M
I
D
V
H
Q
---
L
K
K
S
F
----
G
----
S
L
E
V
L
---
K
G
I
---
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
-------
N
L
L
E
D
F
-----
D
-
E
G
E
I
I
I
D
G
-------------
I
N
L
K
A
-
K
D
T
N
---
L
N
K
V
---
R
E
----
E
-
V
G
M
V
F
Q
R
F
----
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
PMKV
R
--
K
W
P
R
-----
E
-
K
-
A
E
A
K
A
M
E
L
------
L
D
K
V
G
L
----
K
D
K
A
-
H
A
----
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G-
M
--
T
M
--
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
-
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
-
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
10
PsiBlast_PDB
82.06
38%
-48
- C1 -
4YMV
1
?
J:
[4-237]
------------------------
V
N
D
---
V
Y
K
N
F
----
G
----
S
L
E
V
L
---
K
G
V
---
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
-------
N
L
L
E
E
--
P
T
----
K
G
E
V
F
I
D
G
-------------
V
K
I
N
N
-
G
K
V
N
---
I
N
K
V
---
R
Q
----
K
-
V
G
M
V
F
Q
H
F
----
N
-
L
F
P
H
L
T
A
I
E
N
I
T
L
A
----
P
--
V
K
V
K
-----
K
-
M
-
N
K
K
E
A
E
E
L
--
A
V
D
L
L
A
K
V
G
L
L
D
K
-
K
D
Q
Y
--------
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
-
E
G-
M
--
T
M
--
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
-
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
-
E
R
T
R
E
F
L
S
-------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
81.49
33%
-54
- C1 -
4U00
3
?
A:
[4-239]
---------------------
I
I
R
I
R
N
---
L
H
K
W
F
----
G
----
P
L
H
V
L
---
K
G
I
---
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
-------
N
R
L
E
D
F
-----
Q
-
E
G
E
V
V
V
D
G
-------------
L
S
V
-
K
-
D
D
R
A
---
L
R
E
I
---
R
R
----
E
-
V
G
M
V
F
Q
Q
F
----
N
-
L
F
P
H
M
T
V
L
E
N
V
T
L
A
----
P
--
M
R
V
R
-----
R
-
W
-
P
R
E
K
A
E
K
K
--
A
L
E
L
L
E
R
V
G
I
L
D
Q
A
R
-----
K
----
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
A
Q
G
G
--
M
--
T
M
--
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
-
D
G
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
E
-
E
R
T
R
S
F
L
Q
-------------------------------------------------------------------------------------------------
34
PsiBlast_CBE
79.48
33%
-56
- C1 -
4U02
1
?
C:
[4-239]
---------------------
I
I
R
I
R
N
---
L
H
K
W
F
----
G
----
P
L
H
V
L
---
K
G
I
---
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
-------
N
R
L
E
D
F
-----
Q
-
E
G
E
V
V
V
D
G
-------------
L
S
V
-
K
-
D
D
R
A
---
L
R
E
I
---
R
R
----
E
-
V
G
M
V
F
Q
Q
F
----
N
-
L
F
P
H
M
T
V
L
E
N
V
T
L
A
----
P
--
M
R
V
R
-----
R
-
W
-
P
R
E
K
A
E
K
K
--
A
L
E
L
L
E
R
V
G
I
L
D
Q
A
R
-----
K
----
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
A
Q
G
G
--
M
--
T
M
--
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
-
D
G
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
E
-
E
R
T
R
S
F
L
Q
-------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
78.94
33%
-51
- C1 -
4U02
1
?
A:
[4-239]
---------------------
I
I
R
I
R
N
---
L
H
K
W
F
----
G
----
P
L
H
V
L
---
K
G
I
---
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
-------
N
R
L
E
D
F
-----
Q
-
E
G
E
V
V
V
D
G
-------------
L
S
V
-
K
-
D
D
R
A
---
L
R
E
I
---
R
R
----
E
-
V
G
M
V
F
Q
Q
F
----
N
-
L
F
P
H
M
T
V
L
E
N
V
T
L
A
----
P
--
M
R
V
R
-----
R
-
W
-
P
R
E
K
A
E
K
K
--
A
L
E
L
L
E
R
V
G
I
L
D
Q
A
R
-----
K
----
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
A
Q
G
G
--
M
--
T
M
--
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
-
D
G
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
E
-
E
R
T
R
S
F
L
Q
-------------------------------------------------------------------------------------------------
35
PsiBlast_CBE
78.25
33%
-51
- C1 -
4U02
1
?
B:
[4-239]
---------------------
I
I
R
I
R
N
---
L
H
K
W
F
----
G
----
P
L
H
V
L
---
K
G
I
---
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
-------
N
R
L
E
D
F
-----
Q
-
E
G
E
V
V
V
D
G
-------------
L
S
V
-
K
-
D
D
R
A
---
L
R
E
I
---
R
R
----
E
-
V
G
M
V
F
Q
Q
F
----
N
-
L
F
P
H
M
T
V
L
E
N
V
T
L
A
----
P
--
M
R
V
R
-----
R
-
W
-
P
R
E
K
A
E
K
K
--
A
L
E
L
L
E
R
V
G
I
L
D
Q
A
R
-----
K
----
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
A
Q
G
G
--
M
--
T
M
--
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
-
D
G
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
E
-
E
R
T
R
S
F
L
Q
-------------------------------------------------------------------------------------------------
33
PsiBlast_CBE
77.76
33%
-52
- C1 -
4U02
1
?
D:
[4-239]
---------------------
I
I
R
I
R
N
---
L
H
K
W
F
----
G
----
P
L
H
V
L
---
K
G
I
---
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
-------
N
R
L
E
D
F
-----
Q
-
E
G
E
V
V
V
D
G
-------------
L
S
V
-
K
-
D
D
R
A
---
L
R
E
I
---
R
R
----
E
-
V
G
M
V
F
Q
Q
F
----
N
-
L
F
P
H
M
T
V
L
E
N
V
T
L
A
----
P
--
M
R
V
R
-----
R
-
W
-
P
R
E
K
A
E
K
K
--
A
L
E
L
L
E
R
V
G
I
L
D
Q
A
R
-----
K
----
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
A
Q
G
G
--
M
--
T
M
--
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
-
D
G
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
E
-
E
R
T
R
S
F
L
Q
-------------------------------------------------------------------------------------------------
105
Fugue
77.51
32%
6
- C1 -
3TUZ
3
METN_ECOLI
H:
[23-362]
--------------------
H
M
I
K
L
S
N
---
I
T
K
V
F
----
H
QGTR
T
I
Q
A
L
---
N
N
V
---
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
-------
N
L
L
E
R
--
P
T
----
E
G
S
V
L
V
D
G
-------------
Q
E
L
T
T
L
S
E
S
E
---
L
T
K
A
---
R
R
----
Q
-
I
G
M
I
F
Q
H
F
----
N
L
L
S
S
R
-
T
V
F
G
N
V
A
L
P
----
L
--
E
L
D
N
-------
T
-
P
K
D
E
V
K
R
R
--
V
T
E
L
L
S
L
V
G
L
----
G
D
K
H
-
D
S
----
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
-
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
-
R
--
L
GL
T
I
--
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
-
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
K
T
-
P
L
A
Q
K
F
I
Q
S
T
L
H
LDIPEDYQERLQAEPFTDCVPMLRLEFTGQSVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHHVKVEV
1
PsiBlast_PDB
74.08
37%
16
- C1 -
2OLJ
4
?
A:
[22-263]
----------------------
L
Q
M
I
D
V
H
Q
L
K
K
S
F
----
G
----
S
L
E
V
L
---
K
G
I
---
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
-------
N
L
L
E
D
F
-----
D
-
E
G
E
I
I
I
D
G
-------------
I
N
L
K
A
-
K
D
T
N
---
L
N
K
V
---
R
E
----
E
-
V
G
M
V
F
Q
R
F
----
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
PMKV
R
--
K
W
P
R
-----
E
-
K
-
A
E
A
K
A
M
E
L
------
L
D
K
V
G
L
----
K
D
K
A
-
H
A
----
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G-
M
--
T
M
--
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
-
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
-
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
3
PsiBlast_PDB
73.54
37%
12
- C1 -
2OUK
1
?
A:
[22-263]
----------------------
L
Q
M
I
D
V
H
Q
L
K
K
S
F
----
G
----
S
L
E
V
L
---
K
G
I
---
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
-------
N
L
L
E
D
F
-----
D
-
E
G
E
I
I
I
D
G
-------------
I
N
L
K
A
-
K
D
T
N
---
L
N
K
V
---
R
E
----
E
-
V
G
M
V
F
Q
R
F
----
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
--
K
W
P
R
-----
E
-
K
-
A
E
A
K
A
M
E
L
------
L
D
K
V
G
L
----
K
D
K
A
-
H
A
----
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G-
M
--
T
M
--
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
-
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
-
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
21
PsiBlast_CBE
72.91
37%
22
- C1 -
3C4J
4
?
B:
[22-263]
----------------------
L
Q
M
I
D
VHQ
L
K
K
S
F
----
G
----
S
L
E
V
L
---
K
G
I
---
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
-------
N
L
L
E
D
F
-----
D
-
E
G
E
I
I
I
D
G
-------------
I
N
L
K
A
-
K
D
T
N
---
L
N
K
V
---
R
E
----
E
-
V
G
M
V
F
Q
R
F
----
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
PMKV
R
--
K
W
P
R
-----
E
-
K
-
A
E
A
K
A
M
E
L
------
L
D
K
V
G
L
----
K
D
K
A
-
H
A
----
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G-
M
--
T
M
--
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
-
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
-
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
2
PsiBlast_PDB
72.53
37%
12
- C1 -
2OLK
1
?
A:
[22-263]
----------------------
L
Q
M
I
D
V
H
Q
L
K
K
S
F
----
G
----
S
L
E
V
L
---
K
G
I
---
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
-------
N
L
L
E
D
F
-----
D
-
E
G
E
I
I
I
D
G
-------------
I
N
L
K
A
-
K
D
T
N
---
L
N
K
V
---
R
E
----
E
-
V
G
M
V
F
Q
R
F
----
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
PMKV
R
--
K
W
P
R
-----
E
-
K
-
A
E
A
K
A
M
E
L
------
L
D
K
V
G
L
----
K
D
K
A
-
H
A
----
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G-
M
--
T
M
--
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
-
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
-
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
5
PsiBlast_PDB
72.51
37%
23
- C1 -
3C4J
3
?
A:
[22-263]
----------------------
L
Q
M
I
D
V
H
Q
L
K
K
S
F
----
G
----
S
L
E
V
L
---
K
G
I
---
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
-------
N
L
L
E
D
F
-----
D
-
E
G
E
I
I
I
D
G
-------------
I
N
L
K
A
-
K
D
T
N
---
L
N
K
V
---
R
E
----
E
-
V
G
M
V
F
Q
R
F
----
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
--
K
W
P
R
-----
E
-
K
-
A
E
A
K
A
M
E
L
------
L
D
K
V
G
L
----
K
D
K
A
-
H
A
----
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G-
M
--
T
M
--
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
-
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
-
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
27
PsiBlast_CBE
72.34
37%
16
- C1 -
2OLK
1
?
C:
[22-263]
----------------------
L
Q
M
I
D
VHQ
L
K
K
S
F
----
G
----
S
L
E
V
L
---
K
G
I
---
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
-------
N
L
L
E
D
F
-----
D
-
E
G
E
I
I
I
D
G
-------------
I
N
L
K
A
-
K
D
T
N
---
L
N
K
V
---
R
E
----
E
-
V
G
M
V
F
Q
R
F
----
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
PMKV
R
--
K
W
P
R
-----
E
-
K
-
A
E
A
K
A
M
E
L
------
L
D
K
V
G
L
----
K
D
K
A
-
H
A
----
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G-
M
--
T
M
--
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
-
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
-
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
26
PsiBlast_CBE
72.29
37%
22
- C1 -
2OLK
1
?
D:
[22-263]
----------------------
L
Q
M
I
D
VHQ
L
K
K
S
F
----
G
----
S
L
E
V
L
---
K
G
I
---
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
-------
N
L
L
E
D
F
-----
D
-
E
G
E
I
I
I
D
G
-------------
I
N
L
K
A
-
K
D
T
N
---
L
N
K
V
---
R
E
----
E
-
V
G
M
V
F
Q
R
F
----
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
PMKV
R
--
K
W
P
R
-----
E
-
K
-
A
E
A
K
A
M
E
L
------
L
D
K
V
G
L
----
K
D
K
A
-
H
A
----
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G-
M
--
T
M
--
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
-
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
-
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
29
PsiBlast_CBE
72.17
37%
28
- C1 -
2OLJ
3
?
B:
[22-263]
----------------------
L
Q
M
I
D
VHQ
L
K
K
S
F
----
G
----
S
L
E
V
L
---
K
G
I
---
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
-------
N
L
L
E
D
F
-----
D
-
E
G
E
I
I
I
D
G
-------------
I
N
L
K
A
-
K
D
T
N
---
L
N
K
V
---
R
E
----
E
-
V
G
M
V
F
Q
R
F
----
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
PMKV
R
--
K
W
P
R
-----
E
-
K
-
A
E
A
K
A
M
E
L
------
L
D
K
V
G
L
----
K
D
K
A
-
H
A
----
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G-
M
--
T
M
--
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
-
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
-
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
28
PsiBlast_CBE
71.91
37%
18
- C1 -
2OLK
2
?
B:
[22-263]
----------------------
L
Q
M
I
D
VHQ
L
K
K
S
F
----
G
----
S
L
E
V
L
---
K
G
I
---
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
-------
N
L
L
E
D
F
-----
D
-
E
G
E
I
I
I
D
G
-------------
I
N
L
K
A
-
K
D
T
N
---
L
N
K
V
---
R
E
----
E
-
V
G
M
V
F
Q
R
F
----
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
PMKV
R
--
K
W
P
R
-----
E
-
K
-
A
E
A
K
A
M
E
L
------
L
D
K
V
G
L
----
K
D
K
A
-
H
A
----
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G-
M
--
T
M
--
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
-
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
-
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
4
PsiBlast_PDB
70.47
37%
19
- C1 -
2Q0H
4
?
A:
[23-263]
-----------------------
Q
M
I
D
V
H
Q
L
K
K
S
F
----
G
----
S
L
E
V
L
---
K
G
I
---
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
-------
N
L
L
E
D
F
-----
D
-
E
G
E
I
I
I
D
G
-------------
I
N
L
K
A
-
K
D
T
N
---
L
N
K
V
---
R
E
----
E
-
V
G
M
V
F
Q
R
F
----
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
--
K
W
P
R
-----
E
-
K
-
A
E
A
K
A
M
E
L
------
L
D
K
V
G
L
----
K
D
K
A
-
H
A
----
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G-
M
--
T
M
--
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
-
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
-
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
22
PsiBlast_CBE
69.76
37%
18
- C1 -
2Q0H
4
?
B:
[22-263]
----------------------
L
Q
M
I
D
V
H
Q
L
K
K
S
F
----
G
----
S
L
E
V
L
---
K
G
I
---
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
-------
N
L
L
E
D
F
-----
D
-
E
G
E
I
I
I
D
G
-------------
I
N
L
K
A
-
K
D
T
N
---
L
N
K
V
---
R
E
----
E
-
V
G
M
V
F
Q
R
F
----
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
PMKV
R
--
K
W
P
R
-----
E
-
K
-
A
E
A
K
A
M
E
L
------
L
D
K
V
G
L
----
K
D
K
A
-
H
A
----
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G-
M
--
T
M
--
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
-
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
-
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
43
PsiBlast_CBE
62.50
32%
-38
- C1 -
1VCI
1
?
A:
[13-240]
----------------------
V
K
L
E
N
---
L
T
K
R
F
----
G
----
N
F
T
A
V
---
N
K
L
---
N
L
T
I
K
D
G
E
F
L
V
L
L
G
P
S
G
C
G
K
T
T
T
L
R
M
I
-------
A
G
L
E
E
--
P
T
----
E
G
R
I
Y
F
---------------------
G
D
R
D
---
V
T
Y
L
PPK
D
R
----
N
-
I
S
M
V
F
Q
-----------
H
M
T
V
Y
E
N
I
A
F
P
----
L
---------------
K
K
F
P
K
D
E
I
---
D
K
R
V
R
W
A
A
E
L
L
Q
I
E
E
L
L
-
N
R
----
Y
P
A
Q
L
S
G
G
Q
R
Q
R
V
A
V
A
R
A
I
V
V
-
E
P
D
V
L
L
M
D
E
P
L
S
N
L
D
A
K
L
R
V
A
M
R
A
E
I
K
K
L
Q
Q
-
K
--
L
--
K
V
T
T
I
Y
V
T
H
D
Q
V
E
A
M
T
M
G
D
R
I
A
V
M
-
N
R
G
Q
L
L
Q
I
G
S
P
T
E
V
Y
L
R
P
------------------------------------------------------------------------------------------------------------
107
Fugue
61.84
35%
25
- C1 -
1B0U
4
HISP_SALTY
A:
[5-261]
--------------------
N
K
L
H
V
I
D
---
L
H
K
R
Y
----
G
----
G
---
H
---
E
V
L
K
G
V
S
L
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
R
C
I
N
FLEKPS-------------
E
G
A
I
I
V
N
G
QNI
N
L
V
R
D
KDGQL
K
V
A
D
K
-
N
Q
L
R
---
L
L
R
T
----
R
------
L
T
M
V
F
Q
H
F
----
N
-
L
W
S
H
M
T
V
L
E
N
V
M
E
A
----
P
--
I
Q
V
L
------G
L
-
S
K
H
D
A
R
E
R
--
A
L
K
Y
L
A
K
V
G
I
D
E
R
A
Q
G
----
K
----
Y
P
V
H
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
E-
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
E
L
V
G
E
V
L
R
I
M
Q
Q
L
A
E
-
E
G-
K
--
T
M
--
V
V
V
T
H
E
M
G
F
A
R
H
V
S
S
H
V
I
F
L
H
-
Q
G
K
I
E
E
E
G
D
P
E
Q
V
F
G
N
P
-
Q
S
P
R
L
Q
Q
F
L
K
G
S
L
K
KLE------------------------------------------------------------------------------------------
90
PsiBlast_CBE
55.40
34%
-4
- C1 -
3TIF
6
Y796_METJA
B:
[20-223]
-----------------------------------------------
A
L
---
K
N
V
---
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
-------
G
C
L
D
K
--
P
T
----
E
G
E
V
Y
I
D
---------------
N
I
K
T
-
N
D
L
D
DDE
L
T
K
I
---
R
R
----
D
K
I
G
F
V
F
Q
Q
F
----
N
-
L
I
P
L
L
T
A
L
E
N
V
E
L
P
----
L
IF
K
Y
R
G
AMSGE
E
-
R
-
R
K
R
A
L
-------
E
C
L
K
M
A
----
E
L
E
E
R
F
A
N
H
----
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
-
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
-
E
DG
K
--
T
V
--
V
V
V
T
H
D
I
N
V
A
-
R
F
G
E
R
I
I
Y
L
-
K
D
G
E
V
-------------------------------------------------------------------------------------------------------------------------
91
PsiBlast_CBE
54.59
34%
-4
- C1 -
3TIF
7
Y796_METJA
A:
[20-223]
-----------------------------------------------
A
L
---
K
N
V
---
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
-------
G
C
L
D
K
--
P
T
----
E
G
E
V
Y
I
D
---------------
N
I
K
T
-
N
D
L
D
D
D
E
L
T
K
I
---
R
R
----
D
K
I
G
F
V
F
Q
Q
F
----
N
-
L
I
P
L
L
T
A
L
E
N
V
E
L
P
----
L
IF
K
Y
R
G
A
M
S
G
E
E
-
R
-
R
K
R
A
L
-------
E
C
L
K
M
A
----
E
L
E
E
R
F
A
N
H
----
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
-
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
-
E
DG
K
--
T
V
--
V
V
V
T
H
D
I
N
V
A
-
R
F
G
E
R
I
I
Y
L
-
K
D
G
E
V
-------------------------------------------------------------------------------------------------------------------------
88
PsiBlast_CBE
52.32
34%
11
- C1 -
1L2T
4
Y796_METJA
B:
[20-223]
-----------------------------------------------
A
L
---
K
N
V
---
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
-------
G
C
L
D
K
--
P
T
----
E
G
E
V
Y
I
D
---------------
N
I
K
T
-
N
D
L
D
DDE
L
T
K
I
---
R
R
----
D
K
I
G
F
V
F
Q
Q
F
----
N
-
L
I
P
L
L
T
A
L
E
N
V
E
L
P
----
L
IF
K
Y
R
G
AMSGE
E
-
R
-
R
K
R
A
L
-------
E
C
L
K
M
A
E
L
E
E
R
F
A
N
H
K
-
P
N
----
Q
---
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
-
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
-
E
DG
K
--
T
V
--
V
V
V
T
H
D
I
N
V
A
-
R
F
G
E
R
I
I
Y
L
-
K
D
G
E
V
-------------------------------------------------------------------------------------------------------------------------
89
PsiBlast_CBE
52.15
34%
11
- C1 -
1L2T
4
Y796_METJA
A:
[20-223]
-----------------------------------------------
A
L
---
K
N
V
---
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
-------
G
C
L
D
K
--
P
T
----
E
G
E
V
Y
I
D
---------------
N
I
K
T
-
N
D
L
D
D
D
E
L
T
K
I
---
R
R
----
D
K
I
G
F
V
F
Q
Q
F
----
N
-
L
I
P
L
L
T
A
L
E
N
V
E
L
P
----
L
IF
K
Y
R
G
A
M
S
G
E
E
-
R
-
R
K
R
A
L
-------
E
C
L
K
M
A
E
L
E
E
R
F
A
N
H
K
-
P
N
----
Q
---
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
-
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
-
E
DG
K
--
T
V
--
V
V
V
T
H
D
I
N
V
A
-
R
F
G
E
R
I
I
Y
L
-
K
D
G
E
V
-------------------------------------------------------------------------------------------------------------------------
69
PsiBlast_CBE
46.01
31%
22
- C1 -
4AYT
2
ABCBA_HUMAN
A:
[342-567]
----------------------
L
E
F
K
N
---
V
H
F
A
Y
----
P
----
A
R
P
E
V
PIF
Q
D
F
---
S
L
S
I
P
S
G
S
V
T
A
L
V
G
P
S
G
S
G
K
S
T
V
L
S
L
L
-------
L
R
L
Y
D
-----
P
A
-
S
G
T
I
S
L
D
G
-------------
H
D
I
R
---
Q
L
N
---
P
V
W
L
---
R
S
----
K
-
I
G
T
V
S
Q
E
P
----
I
-
L
F
S
C
-
S
I
A
E
N
I
A
Y
G
---------
A
D
-----
D
-
P
-
S
S
V
T
A
E
E
I
Q
R
V
A
E
V
A
N
A
V
A
F
I
R
N
F
P
Q
G
F
-
N
T
VVGE
K
G
V
L
L
S
G
G
Q
K
Q
R
I
A
I
A
R
A
L
L
K
-
N
P
K
I
L
L
L
D
E
A
T
S
A
L
D
A
E
N
E
Y
L
V
Q
E
A
L
D
R
L
M
D
-
G
--
R
--
T
V
--
L
V
I
A
H
R
L
-
S
T
I
K
N
A
N
M
V
A
V
L
-
D
Q
G
K
I
T
E
Y
G
K
H
E
E
-----------------------------------------------------------------------------------------------------------------
67
PsiBlast_CBE
44.63
31%
29
- C1 -
4AYW
1
ABCBA_HUMAN
A:
[373-598]
----------------------
L
E
F
K
N
---
V
H
F
A
Y
----
P
----
A
R
P
E
V
PIF
Q
D
F
---
S
L
S
I
P
S
G
S
V
T
A
L
V
G
P
S
G
S
G
K
S
T
V
L
S
L
L
-------
L
R
L
Y
D
-----
P
A
-
S
G
T
I
S
L
D
G
-------------
H
D
I
R
---
Q
L
N
---
P
V
W
L
---
R
S
----
K
-
I
G
T
V
S
Q
E
P
----
I
-
L
F
S
C
-
S
I
A
E
N
I
A
Y
G
---------
A
D
-----
D
-
P
-
S
S
V
T
A
E
E
I
Q
R
V
A
E
V
A
N
A
V
A
F
I
R
N
F
P
Q
G
F
-
N
T
V
V
G
E
K
G
V
L
L
S
G
G
Q
K
Q
R
I
A
I
A
R
A
L
L
K
-
N
P
K
I
L
L
L
D
E
----
L
D
A
E
N
E
Y
L
V
Q
E
A
L
D
R
L
M
D
-
G
--
R
--
T
V
--
L
V
I
A
H
H
L
-
S
T
I
K
N
A
N
M
V
A
V
L
-
D
Q
G
K
I
T
E
Y
G
K
H
E
E
-----------------------------------------------------------------------------------------------------------------