@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu25290: (2016-07-10 )
MNEKNIKHSQNFITSKHNIDKIMTNIRLNEHDNIFEIGSGKGHFTLELVQRCNFVTAIEIDHKLCKTTENKLVDHDNFQVLNKDILQFKFPKNQSYKIFGNIPYNISTDIIRKIVFDSIADEIYLIVEYGFAKRLLNTKRSLALFLMAEVDISILSMVPREYFHPKPKVNSSLIRLNRKKSRISHKDKQKYNYFVMKWVNKEYKKIFTKNQFNNSLKHAGIDDLNNISFEQFLSLFNSYKLFNK
Atome Classification :
(22 SA)
.........10........20........30........40........50----........60........70...-.----....80........90------.-----.......100.......110...--.--...--120.......130....---.--.---.---140----........150.....--..160.......170....---------...180....--....190.......200-------.......-----------------------------210..-----.....220--..---......230.......240..-
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MNEKNI
K
H
S
Q
N
F
ITSKH
N
I
D
K
I
M
T
NIRLNEHD
N
I
F
E
IGSGKG
H
F
T
L
E
L
V
Q
R----CN
F
V
T
A
I
E
I
D
H
K
L
C
KTTENKLVD-H----DNF
Q
V
L
N
KDI
L
Q
F
KFP------K-----NQ
S
Y
K
I
FGNIPYNI
S
T
D
I
I
R
K
I
V
--
F
--
D
S
I--A
D
E
I
Y
L
I
V
EY
G
F
A
K
R
L
L
---N--T---
K
---
R
S
-----
L
A
L
F
L
M
AEV
D
I
S
I
L
S
M--V
P
R
E
YFHPKPKV
N
S
S
L
I
R
L
---------
N
R
K
K
S-RISH--KDKQKY
N
Y
F
V
M
K
W
V
N
K
E
-------
Y
K
K
I
F
T
K
-----------------------------
N
QFNN-----SLKHAGI---DD---LNNI
S
F
E
Q
F
L
S
L
F
N
S
Y
KLFNK-
5
PsiBlast_PDB
98.94
100%
-140
- C1 -
1QAQ
1
ERM_BACIU
A:
[9-244]
--------
S
Q
N
F
I
T
S
K
H
N
I
D
K
I
M
T
N
I
R
L
N
E
H
D
N
I
F
E
I
G
S
G
K
G
H
F
T
L
E
L
V
Q
R
----
C
N
F
V
T
A
I
E
I
D
H
K
L
C
K
T
T
E
N
K
L
V
D
-
H
----
D
N
F
Q
V
L
N
K
D
I
L
Q
F
K
F
P
------
K
-----
N
Q
S
Y
K
I
F
G
N
I
P
Y
N
I
S
T
D
I
I
R
K
I
V
--
F
--
D
S
I
--
A
D
E
I
Y
L
I
V
E
Y
G
F
A
K
R
L
L
---
N
--
T
---
K
---
R
S
-----
L
A
L
F
L
M
A
E
V
D
I
S
I
L
S
M
--
V
P
R
E
Y
F
H
P
K
P
K
V
N
S
S
L
I
R
L
---------
N
R
K
K
S
-
R
I
S
H
--
K
D
K
Q
K
Y
N
Y
F
V
M
K
W
V
N
K
E
-------
Y
K
K
I
F
T
K
-----------------------------
N
Q
F
N
N
-----
S
L
K
H
A
G
I
---
D
D
---
L
N
N
I
S
F
E
Q
F
L
S
L
F
N
S
Y
K
L
F
N
K
-
2
PsiBlast_PDB
98.94
100%
-139
- C1 -
1QAM
2
ERM_BACIU
A:
[10-244]
---------
Q
N
F
I
T
S
K
H
N
I
D
K
I
M
T
N
I
R
L
N
E
H
D
N
I
F
E
I
G
S
G
K
G
H
F
T
L
E
L
V
Q
R
----
C
N
F
V
T
A
I
E
I
D
H
K
L
C
K
T
T
E
N
K
L
V
D
-
H
----
D
N
F
Q
V
L
N
K
D
I
L
Q
F
K
F
P
------
K
-----
N
Q
S
Y
K
I
F
G
N
I
P
Y
N
I
S
T
D
I
I
R
K
I
V
--
F
--
D
S
I
--
A
D
E
I
Y
L
I
V
E
Y
G
F
A
K
R
L
L
---
N
--
T
---
K
---
R
S
-----
L
A
L
F
L
M
A
E
V
D
I
S
I
L
S
M
--
V
P
R
E
Y
F
H
P
K
P
K
V
N
S
S
L
I
R
L
---------
N
R
K
K
S
-
R
I
S
H
--
K
D
K
Q
K
Y
N
Y
F
V
M
K
W
V
N
K
E
-------
Y
K
K
I
F
T
K
-----------------------------
N
Q
F
N
N
-----
S
L
K
H
A
G
I
---
D
D
---
L
N
N
I
S
F
E
Q
F
L
S
L
F
N
S
Y
K
L
F
N
K
-
3
PsiBlast_PDB
98.81
100%
-138
- C1 -
1QAN
3
ERM_BACIU
A:
[9-244]
--------
S
Q
N
F
I
T
S
K
H
N
I
D
K
I
M
T
N
I
R
L
N
E
H
D
N
I
F
E
I
G
S
G
K
G
H
F
T
L
E
L
V
Q
R
----
C
N
F
V
T
A
I
E
I
D
H
K
L
C
K
T
T
E
N
K
L
V
D
-
H
----
D
N
F
Q
V
L
N
K
D
I
L
Q
F
K
F
P
------
K
-----
N
Q
S
Y
K
I
F
G
N
I
P
Y
N
I
S
T
D
I
I
R
K
I
V
--
F
--
D
S
I
--
A
D
E
I
Y
L
I
V
E
Y
G
F
A
K
R
L
L
---
N
--
T
---
K
---
R
S
-----
L
A
L
F
L
M
A
E
V
D
I
S
I
L
S
M
--
V
P
R
E
Y
F
H
P
K
P
K
V
N
S
S
L
I
R
L
---------
N
R
K
K
S
-
R
I
S
H
--
K
D
K
Q
K
Y
N
Y
F
V
M
K
W
V
N
K
E
-------
Y
K
K
I
F
T
K
-----------------------------
N
Q
F
N
N
-----
S
L
K
H
A
G
I
---
D
D
---
L
N
N
I
S
F
E
Q
F
L
S
L
F
N
S
Y
K
L
F
N
K
-
4
PsiBlast_PDB
98.71
100%
-137
- C1 -
1QAO
1
ERM_BACIU
A:
[9-244]
--------
S
Q
N
F
I
T
S
K
H
N
I
D
K
I
M
T
N
I
R
L
N
E
H
D
N
I
F
E
I
G
S
G
K
G
H
F
T
L
E
L
V
Q
R
----
C
N
F
V
T
A
I
E
I
D
H
K
L
C
K
T
T
E
N
K
L
V
D
-
H
----
D
N
F
Q
V
L
N
K
D
I
L
Q
F
K
F
P
------
K
-----
N
Q
S
Y
K
I
F
G
N
I
P
Y
N
I
S
T
D
I
I
R
K
I
V
--
F
--
D
S
I
--
A
D
E
I
Y
L
I
V
E
Y
G
F
A
K
R
L
L
---
N
--
T
---
K
---
R
S
-----
L
A
L
F
L
M
A
E
V
D
I
S
I
L
S
M
--
V
P
R
E
Y
F
H
P
K
P
K
V
N
S
S
L
I
R
L
---------
N
R
K
K
S
-
R
I
S
H
--
K
D
K
Q
K
Y
N
Y
F
V
M
K
W
V
N
K
E
-------
Y
K
K
I
F
T
K
-----------------------------
N
Q
F
N
N
-----
S
L
K
H
A
G
I
---
D
D
---
L
N
N
I
S
F
E
Q
F
L
S
L
F
N
S
Y
K
L
F
N
K
-
1
PsiBlast_PDB
93.63
100%
-146
- C1 -
2ERC
-
ERM_BACIU
A:
[10-244]
---------
Q
N
F
I
T
S
K
H
N
I
D
K
I
M
T
N
I
R
L
N
E
H
D
N
I
F
E
I
G
S
G
K
G
H
F
T
L
E
L
V
Q
R
----
C
N
F
V
T
A
I
E
I
D
H
K
L
C
K
T
T
E
N
K
L
V
D
-
H
----
D
N
F
Q
V
L
N
K
D
I
L
Q
F
K
F
P
------
K
-----
N
Q
S
Y
K
I
F
G
N
I
P
Y
N
I
S
T
D
I
I
R
K
I
V
--
F
--
D
S
I
--
A
D
E
I
Y
L
I
V
E
Y
G
F
A
K
R
L
L
---
N
--
T
---
K
---
R
S
-----
L
A
L
F
L
M
A
E
V
D
I
S
I
L
S
M
--
V
P
R
E
Y
F
H
P
K
P
K
V
N
S
S
L
I
R
L
---------
N
R
K
K
S
-
R
I
S
H
--
K
D
K
Q
K
Y
N
Y
F
V
M
K
W
V
N
K
E
-------
Y
K
K
I
F
T
K
-----------------------------
N
Q
F
N
N
-----
S
L
K
H
A
G
I
---
D
D
---
L
N
N
I
S
F
E
Q
F
L
S
L
F
N
S
Y
K
L
F
N
K
-
36
HHSearch
89.82
99%
-43
- C1 -
1QAM
2
ERM_BACIU
A:
[10-243]
---------
Q
N
F
I
T
S
K
H
N
I
D
K
I
M
T
N
I
R
L
N
E
H
D
N
I
F
E
I
G
S
G
K
G
H
F
T
L
E
L
V
Q
R
----
C
N
F
V
T
A
I
E
I
D
H
K
L
C
K
T
T
E
N
K
L
-
V
-
D
H---
D
N
F
Q
V
L
N
K
D
I
L
Q
F
K
F
P
------
K
-----
N
Q
S
Y
K
I
F
G
N
I
P
Y
N
I
S
T
D
I
I
R
K
I
V
--
F
--
D
S
I
--
A
D
E
I
Y
L
I
V
E
Y
G
F
A
K
R
L
L
---
N
--
T
---
K
---
R
S
-----
L
A
L
F
L
M
A
E
V
D
I
S
I
L
S
M
--
V
P
R
E
Y
F
H
P
K
P
K
V
N
S
S
L
I
R
L
---------
N
R
K
K
S
-
R
I
S
H
--
K
D
K
Q
K
Y
N
Y
F
V
M
K
W
V
N
K
E
-------
Y
K
K
I
F
T
K
-----------------------------
N
Q
F
N
N
-----
S
L
K
H
A
G
I
---
D
D
---
L
N
N
I
S
F
E
Q
F
L
S
L
F
N
S
Y
K
L
F
N
--
25
Fugue
86.18
99%
-50
- C1 -
2ERC
-
ERM_BACIU
A:
[10-244]
---------
Q
N
F
I
T
S
K
H
N
I
D
K
I
M
T
N
I
R
L
N
E
H
D
N
I
F
E
I
G
S
G
K
G
H
F
T
L
E
L
V
Q
R
----
C
N
F
V
T
A
I
E
I
D
H
K
L
C
K
T
T
E
N
K
L
V
D
H
D
-----
N
F
Q
V
L
N
K
D
I
L
Q
F
K
F
P
------
K
-----
N
Q
S
Y
K
I
F
G
N
I
P
Y
N
I
S
T
D
I
I
R
K
I
V
--
F
--
D
S
I
--
A
D
E
I
Y
L
I
V
E
Y
G
F
A
K
R
L
L
---
N
--
T
---
K
---
R
S
-----
L
A
L
F
L
M
A
E
V
D
I
S
I
L
S
M
--
V
P
R
E
Y
F
H
P
K
P
K
V
N
S
S
L
I
R
L
---------
N
R
K
K
S
-
R
I
S
H
--
K
D
K
Q
K
Y
N
Y
F
V
M
K
W
V
N
K
E
-------
Y
K
K
I
F
T
K
-----------------------------
N
Q
F
N
N
-----
S
L
K
H
A
G
I
---
D
D
---
L
N
N
I
S
F
E
Q
F
L
S
L
F
N
S
Y
K
L
F
N
-K
6
PsiBlast_PDB
74.78
50%
-122
- C1 -
1YUB
-
ERM_STREE
A:
[3-242]
---
K
N
I
K
Y
S
Q
N
F
L
T
S
E
K
V
L
N
Q
I
I
K
Q
L
N
L
K
E
T
D
T
V
Y
E
I
G
T
G
K
G
H
L
T
T
K
L
A
K
I
----
S
K
Q
V
T
S
I
E
L
D
S
H
L
F
N
L
S
S
E
K
L
K
L
-
N
----
T
R
V
T
L
I
H
Q
D
I
L
Q
F
Q
F
P
------
N
-----
K
Q
R
Y
K
I
V
G
N
I
P
Y
H
L
S
T
Q
I
I
K
K
V
V
--
F
--
E
S
R
--
A
S
D
I
Y
L
I
V
E
E
G
F
Y
K
R
T
L
---
D
--
I
---
H
---
R
T
-----
L
G
L
L
L
H
T
Q
V
S
I
Q
Q
L
L
K
--
L
P
A
E
C
F
H
P
K
P
K
V
N
S
V
L
I
K
L
---------
T
R
H
T
T
-
D
V
P
D
--
K
Y
W
K
L
Y
T
Y
F
V
S
K
W
V
N
R
E
-------
Y
R
Q
L
F
T
K
-----------------------------
N
Q
F
H
Q
-----
A
M
K
H
A
K
V
---
N
N
---
L
S
T
I
T
Y
E
Q
V
L
S
I
F
N
S
Y
L
L
F
N
--
37
HHSearch
69.62
51%
-27
- C1 -
1YUB
-
ERM_STREE
A:
[2-242]
--
N
K
N
I
K
Y
S
Q
N
F
L
T
S
E
K
V
L
N
Q
I
I
K
Q
L
N
L
K
E
T
D
T
V
Y
E
I
G
T
G
K
G
H
L
T
T
K
L
A
K
I
----
S
K
Q
V
T
S
I
E
L
D
S
H
L
F
N
L
S
S
E
K
L
-
K
-
L
N---
T
R
V
T
L
I
H
Q
D
I
L
Q
F
Q
F
P
------
N
-----
K
Q
R
Y
K
I
V
G
N
I
P
Y
H
L
S
T
Q
I
I
K
K
V
V
--
F
--
E
S
R
--
A
S
D
I
Y
L
I
V
E
E
G
F
Y
K
R
T
L
---
D
--
I
---
H
---
R
T
-----
L
G
L
L
L
H
T
Q
V
S
I
Q
Q
L
L
K
--
L
P
A
E
C
F
H
P
K
P
K
V
N
S
V
L
I
K
L
---------
T
R
H
T
T
-
D
V
P
D
--
K
Y
W
K
L
Y
T
Y
F
V
S
K
W
V
N
R
E
-------
Y
R
Q
L
F
T
K
-----------------------------
N
Q
F
H
Q
-----
A
M
K
H
A
K
V
---
N
N
---
L
S
T
I
T
Y
E
Q
V
L
S
I
F
N
S
Y
L
L
F
N
--
15
PsiBlast_PDB
64.21
27%
-18
- C1 -
3TPZ
2
RSMA_ECOLI
A:
[15-262]
-------
F
G
Q
N
F
L
N
D
Q
F
V
I
D
S
I
V
S
A
I
N
P
Q
K
G
Q
A
M
V
E
I
G
P
G
L
A
A
L
T
E
P
V
G
E
R
----
L
D
Q
L
T
V
I
E
L
D
R
D
L
A
A
R
L
Q
T
H
P
F
L
-
G
----
P
K
L
T
I
Y
Q
Q
D
A
M
T
F
N
F
G
------
E
L
A
E
K
M
G
Q
P
L
R
V
F
G
N
P
P
Y
N
I
S
T
P
L
M
F
H
L
F
S
Y
T
--
D
A
I
--
A
D
-
M
H
F
M
L
Q
K
E
V
V
N
R
L
V
AGP
N
--
S
---
K
---
A
Y
-----
G
R
L
S
V
M
A
Q
Y
Y
C
N
V
I
P
V
L
E
V
P
P
S
A
F
T
P
P
P
K
V
D
S
A
V
V
R
L
----------
V
P
H
A
-
T
M
P
H
PV
K
D
V
R
V
L
S
R
I
T
T
E
A
F
N
Q
R
-------
R
K
T
I
--
R
-----------------------------
N
S
L
G
N
LFS
V
E
V
L
T
G
M
G
I
---
D
P
AMR
A
E
N
I
S
V
A
Q
Y
C
Q
M
A
N
--------
14
PsiBlast_PDB
64.00
27%
-13
- C1 -
4ADV
-
RSMA_ECOLI
V:
[17-262]
---------
Q
N
F
L
N
D
Q
F
V
I
D
S
I
V
S
A
I
N
P
Q
K
G
Q
A
M
V
E
I
G
P
G
L
A
A
L
T
E
P
V
G
E
R
----
L
D
Q
L
T
V
I
E
L
D
R
D
L
A
A
R
L
Q
T
H
P
F
L
-
G
----
P
K
L
T
I
Y
Q
Q
D
A
M
T
F
N
F
G
------
E
LAEKM
G
Q
P
L
R
V
F
G
N
L
P
Y
N
I
S
T
P
L
M
F
H
L
F
SY
T
--
D
A
I
--
A
D
-
M
H
F
M
L
Q
K
E
V
V
N
R
L
V
AGP
N
--
S
---
K
---
A
Y
-----
G
R
L
S
V
M
A
Q
Y
Y
C
N
V
I
P
V
LE
V
P
P
S
A
F
T
P
P
P
K
V
D
S
A
V
V
R
L
----------
V
P
H
A
-
T
M
P
H
PV
K
D
V
R
V
L
S
R
I
T
T
E
A
F
N
Q
R
-------
R
K
T
I
--
R
-----------------------------
N
S
L
G
N
LFSVE
V
L
T
G
M
G
I
---
D
P
AMR
A
E
N
I
S
V
A
Q
Y
C
Q
M
A
N
--------
13
PsiBlast_PDB
64.00
27%
-13
- C1 -
1QYR
-
RSMA_ECOLI
A:
[17-262]
---------
Q
N
F
L
N
D
Q
F
V
I
D
S
I
V
S
A
I
N
P
Q
K
G
Q
A
M
V
E
I
G
P
G
L
A
A
L
T
E
P
V
G
E
R
----
L
D
Q
L
T
V
I
E
L
D
R
D
L
A
A
R
L
Q
T
H
P
F
L
-
G
----
P
K
L
T
I
Y
Q
Q
D
A
M
T
F
N
F
G
------
E
L
A
E
K
M
G
Q
P
L
R
V
F
G
N
L
P
Y
N
I
S
T
P
L
M
F
H
L
F
S
Y
T
--
D
A
I
--
A
D
-
M
H
F
M
L
Q
K
E
V
V
N
R
L
V
AGP
N
--
S
---
K
---
A
Y
-----
G
R
L
S
V
M
A
Q
Y
Y
C
N
V
I
P
V
L
E
V
P
P
S
A
F
T
P
P
P
K
V
D
S
A
V
V
R
L
----------
V
P
H
A
-
T
M
P
H
PV
K
D
V
R
V
L
S
R
I
T
T
E
A
F
N
Q
R
-------
R
K
T
I
--
R
-----------------------------
N
S
L
G
N
LFS
V
E
V
L
T
G
M
G
I
---
D
P
AMR
A
E
N
I
S
V
A
Q
Y
C
Q
M
A
N
--------
43
HHSearch
62.63
24%
-17
- C1 -
1QYR
-
RSMA_ECOLI
A:
[17-267]
---------
Q
N
F
L
N
D
Q
F
V
I
D
S
I
V
S
A
I
N
P
Q
K
G
Q
A
M
V
E
I
G
P
G
L
A
A
L
T
E
P
V
G
E
R
----
L
D
Q
L
T
V
I
E
L
D
R
D
L
A
A
R
L
Q
T
H
P
-
F
-
L
G
---
P
K
L
T
I
Y
Q
Q
D
A
M
T
F
N
F
G
------
E
L
A
E
K
M
G
Q
P
L
R
V
F
G
N
L
P
Y
N
I
S
T
P
L
M
F
H
L
F
--
S
--
Y
T
D
A-
I
A
D
M
H
F
M
L
Q
K
E
V
V
N
R
L
V
---
A
GP
N
SKA
Y
---
G
R
-----
L
S
V
M
A
Q
Y
Y
C
N
V
I
P
V
L
E
--
V
P
P
S
A
F
T
P
P
P
K
V
D
S
A
V
V
R
L
---------
V
P
H
A
T
M
P
H
P
V
--
K
D
V
R
V
L
S
R
I
T
T
E
A
F
N
Q
R
RKT----
I
R
N
S
L
G
N
-----------------------------
L
F
S
V
E
-----
V
L
T
G
M
G
I
DPA
M
R
---
A
E
N
I
S
V
A
Q
Y
C
Q
M
A
N
Y
L
A
E
N
---
46
HHSearch
57.60
22%
-14
- C1 -
1ZQ9
1
DIM1_HUMAN
A:
[8-279]
---------
Q
H
I
L
K
N
P
L
I
I
N
S
I
I
D
K
A
A
L
R
P
T
D
V
V
L
E
V
G
P
G
T
G
N
M
T
V
K
L
L
E
K
----
A
K
K
V
V
A
C
E
L
D
P
R
L
V
A
E
L
H
K
R
V
-
Q
-
G
TPVA
S
K
L
Q
V
L
V
G
D
V
L
K
T
D
L
-------------
P
F
F
D
T
C
V
A
N
L
P
Y
Q
I
S
S
P
F
V
F
K
L
L
--
L
--
H
R
P
F-
F
R
C
A
I
L
M
F
Q
R
E
F
A
L
R
L
V
---
A
KP
G
---
D
KLY
C
R
-----
L
S
I
N
T
Q
L
L
A
R
V
D
H
L
M
K
--
V
G
K
N
N
F
R
P
P
P
K
V
E
S
S
V
V
R
I
---------
E
P
K
N
P
-
P
P
-
P
--
I
N
F
Q
E
W
D
G
L
V
R
I
T
F
V
R
K
NKT----
L
S
A
A
F
K
S
S
A
V
Q
Q
L
L
E
K
N
Y
R
I
H
C
S
V
H
N
I
I
I
P
EDFS
I
A
D
K
I
Q
Q
-----
I
L
T
S
T
G
F
SD-
K
R
---
A
R
S
M
D
I
D
D
F
I
R
L
L
H
G
F
N
A
----
38
HHSearch
56.75
21%
8
- C1 -
3UZU
2
RSMA_BURPS
A:
[18-276]
-----
K
R
F
G
Q
N
F
L
V
D
H
G
V
I
D
A
I
V
A
A
I
R
P
E
R
G
E
R
M
V
E
I
G
P
G
L
G
A
L
T
G
P
V
I
A
R
LATP
G
S
P
L
H
A
V
E
L
D
R
D
L
I
G
R
L
E
Q
R
F
-
G
------
E
L
L
E
L
H
A
G
D
A
L
T
F
D
F
G
SIARPG
D
-----
E
P
S
L
R
I
I
G
N
L
P
Y
N
I
S
S
P
L
L
F
H
L
M
--
S
--
F
A
P
V-
V
I
D
Q
H
F
M
L
Q
N
E
V
V
E
R
M
V
---
A
EP
G
TKA
F
---
S
R
-----
L
S
V
M
L
Q
Y
R
Y
V
M
D
K
L
I
D
--
V
P
P
E
S
F
Q
P
P
P
K
V
D
S
A
I
V
R
M
---------
I
P
H
A
P
H
E
L
P
A
--
V
D
P
A
V
L
G
E
V
V
T
A
A
F
S
Q
R
RKM----
L
R
N
T
L
G
G
-----------------------------
Y
R
D
L
V
-----
D
F
D
A
L
G
F
DLA
R
R
---
A
E
D
I
G
V
D
E
Y
V
R
V
A
Q
A
V
A
S
A
R
--
20
PsiBlast_PDB
56.61
27%
-3
- C- -
3FTD
-
RSMA_AQUAE
A:
[9-240]
--------
G
Q
H
L
L
V
S
E
G
V
L
K
K
I
A
E
E
L
N
I
E
E
G
N
T
V
V
E
V
G
G
G
T
G
N
L
T
K
V
L
L
Q
H
P---
L
K
K
L
Y
V
I
E
L
D
R
E
M
V
E
N
L
--
K
S
I
G
-
D
----
E
R
L
E
V
I
N
E
D
A
S
K
F
P
F
C
------
S
L----
G
K
E
L
K
V
V
G
N
L
P
Y
N
V
A
S
L
I
I
E
N
T
V
--
Y
N
K
D
C
V
--
P
L
A
V
F
M
-
V
Q
K
E
V
A
E
K
L
Q
---
G
--
K
---
K
---
D
T
G
W
---
L
S
V
F
V
R
T
F
Y
D
V
N
Y
V
M
T
--
V
P
P
R
F
F
V
P
P
P
K
V
Q
S
A
V
I
K
L
----------
V
K
N
E
-
K
F
P
V
--
K
D
L
K
N
Y
K
K
F
L
T
K
-
I
F
Q
N
-------
R
R
K
V
L
R
K
-----------------------------
K
I
P
E
E
-----
L
L
K
E
A
G
I
---
N
P
DAR
V
E
Q
L
S
L
E
D
F
F
K
L
Y
---------
11
PsiBlast_PDB
56.52
31%
-36
- C1 -
3FYC
4
RSMA_METJA
A:
[2-179]
--------
A
Q
C
F
L
I
D
K
N
F
V
N
K
A
V
E
S
A
N
L
T
K
D
D
V
V
L
E
I
G
L
G
K
G
I
L
T
E
E
L
A
K
N
----
A
K
K
V
Y
V
I
E
I
D
K
S
L
-
E
P
Y
A
N
K
L
K
E
L
Y
----
N
N
I
E
I
I
W
G
D
A
L
K
V
D
L
N
------
K
-----
L
D
F
N
K
V
V
A
N
L
P
Y
Q
I
S
S
P
I
T
F
K
L
I
--
K
--
R
G
F
---
D
L
A
V
L
M
Y
Q
Y
E
F
A
K
R
M
V
---
A
--
K
---
E
---
G
T
KDYG
R
L
S
V
A
V
Q
S
R
A
D
V
E
I
V
A
K
--
V
P
P
S
A
F
Y
P
K
P
K
V
Y
S
A
I
V
K
I
---------
K
P
N
K
G
-
K
----------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
56.39
27%
8
- C1 -
3R9X
2
RSMA_AQUAE
B:
[13-240]
------------
L
V
S
E
G
V
L
K
K
I
A
E
E
L
N
I
E
E
G
N
T
V
V
E
V
G
G
G
T
G
N
L
T
K
V
L
L
Q
H
P---
L
K
K
L
Y
V
I
E
L
D
R
E
M
V
E
N
L
--
K
S
I
G
-
D
----
E
R
L
E
V
I
N
E
D
A
S
K
F
P
F
C
------
S
L----
G
K
E
L
K
V
V
G
N
L
P
Y
N
V
A
S
L
I
I
E
N
T
V
--
Y
N
K
D
C
V
--
P
L
A
V
F
M
-
V
Q
K
E
V
A
E
K
L
Q
---
G
--
K
---
K
---
D
T
G
W
---
L
S
V
F
V
R
T
F
Y
D
V
N
Y
V
M
T
--
V
P
P
R
F
F
V
P
P
P
K
V
Q
S
A
V
I
K
L
----------
V
K
N
E
-
K
F
P
V
--
K
D
L
K
N
Y
K
K
F
L
T
K
-
I
F
Q
N
-------
R
R
K
V
L
R
K
-----------------------------
K
I
P
E
E
-----
L
L
K
E
A
G
I
---
N
P
DAR
V
E
Q
L
S
L
E
D
F
F
K
L
Y
---------
41
HHSearch
56.35
24%
-21
- C1 -
3TQS
-
RSMA_COXBU
A:
[12-258]
---------
Q
H
F
L
H
D
S
F
V
L
Q
K
I
V
S
A
I
H
P
Q
K
T
D
T
L
V
E
I
G
P
G
R
G
A
L
T
D
Y
L
L
T
E
----
C
D
N
L
A
L
V
E
I
D
R
D
L
V
A
F
L
Q
K
K
Y
-
N
-
Q
Q---
K
N
I
T
I
Y
Q
N
D
A
L
Q
F
D
F
S
------
S
VKT--
D
K
P
L
R
V
V
G
N
L
P
Y
N
I
S
T
P
L
L
F
H
L
F
--
S
--
Q
I
H
C-
I
E
D
M
H
F
M
L
Q
K
E
V
V
R
R
I
T
---
A
EV
G
SHD
Y
---
G
R
-----
L
S
V
M
A
Q
Y
F
C
D
N
T
Y
L
F
T
--
V
S
P
Q
A
F
T
P
P
P
R
V
E
S
A
I
I
R
L
---------
I
P
R
H
N
F
T
P
V
A
--
K
N
L
D
Q
L
S
H
V
V
K
E
A
F
S
Y
R
RKT
V
G
N
A
L
K
K
L
I
N
P
-----------------------------
S
Q
W
P
---------
L
L
E
I
NPQ
L
R
---
P
Q
E
L
T
V
E
D
F
V
K
I
S
N
I
L
N
-----
16
PsiBlast_PDB
56.35
25%
-36
- C1 -
3TQS
-
RSMA_COXBU
A:
[12-231]
---------
Q
H
F
L
H
D
S
F
V
L
Q
K
I
V
S
A
I
H
P
Q
K
T
D
T
L
V
E
I
G
P
G
R
G
A
L
T
D
Y
L
L
T
E
----
C
D
N
L
A
L
V
E
I
D
R
D
L
V
A
F
L
Q
K
K
Y
N
Q
-
Q
----
K
N
I
T
I
Y
Q
N
D
A
L
Q
F
D
F
S
------
S
VKT--
D
K
P
L
R
V
V
G
N
L
P
Y
N
I
S
T
P
L
L
F
H
L
---
F
--
S
Q
I
HC
I
E
D
M
H
F
M
L
Q
K
E
V
V
R
R
I
T
---
A
--
E
---
V
---
G
S
HDYG
R
L
S
V
M
A
Q
Y
F
C
D
N
T
Y
L
F
T
--
V
S
P
Q
A
F
T
P
P
P
R
V
E
S
A
I
I
R
L
I
P
R
H
NFTPV
A
K
N
L
D
-
Q
L
S
H
--
V
V
K
E
A
F
S
Y
-
R
R
K
T
V
G
N
A
-------
L
K
K
L
I
N
P
-----------------------------
S
Q
W
--------------------------------------------
9
PsiBlast_PDB
54.76
31%
-28
- C1 -
3GRV
3
RSMA_METJA
A:
[30-206]
---------
Q
C
F
L
I
D
K
N
F
V
N
K
A
V
E
S
A
N
L
T
K
D
D
V
V
L
E
I
G
L
G
K
G
I
L
T
E
E
L
A
K
N
----
A
K
K
V
Y
V
I
E
I
D
K
S
L
-
E
P
Y
A
N
K
L
K
E
L
Y
----
N
N
I
E
I
I
W
G
D
A
L
K
V
D
L
N
------
K
-----
L
D
F
N
K
V
V
A
N
L
P
Y
Q
I
S
S
P
I
T
F
K
L
I
--
K
--
R
G
F
---
D
L
A
V
L
M
Y
Q
Y
E
F
A
K
R
M
V
---
A
--
A
---
A
---
G
T
KDYG
R
L
S
V
A
V
Q
S
R
A
D
V
E
I
V
A
K
--
V
P
P
S
A
F
Y
P
K
P
K
V
Y
S
A
I
V
K
I
---------
K
P
N
K
G
-
K
----------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
54.04
31%
-30
- C1 -
3GRU
4
RSMA_METJA
A:
[30-206]
---------
Q
C
F
L
I
D
K
N
F
V
N
K
A
V
E
S
A
N
L
T
K
D
D
V
V
L
E
I
G
L
G
K
G
I
L
T
E
E
L
A
K
N
----
A
K
K
V
Y
V
I
E
I
D
K
S
L
-
E
P
Y
A
N
K
L
K
E
L
Y
----
N
N
I
E
I
I
W
G
D
A
L
K
V
D
L
N
------
K
-----
L
D
F
N
K
V
V
A
N
L
P
Y
Q
I
S
S
P
I
T
F
K
L
I
--
K
--
R
G
F
---
D
L
A
V
L
M
Y
Q
Y
E
F
A
K
R
M
V
---
A
--
A
---
A
---
G
T
KDYG
R
L
S
V
A
V
Q
S
R
A
D
V
E
I
V
A
K
--
V
P
P
S
A
F
Y
P
K
P
K
V
Y
S
A
I
V
K
I
---------
K
P
N
K
G
-
K
----------------------------------------------------------------------------------------------------------------