@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu25350: (2016-07-10 )
MKNKWLSFFSGKVQLELTGRGIERLLNECTRQGIPVFHVKKKKEAVSLYIQLQDVHAFRRVRSKFKCKARFINRKGFPFLLLKSKLNIGFTIGFAIFFILLFLLSNMVWKIDVTGAKPETEHQMRQHLNEIGVKKGRLQFLMMSPEKIQKSLTNGIDNITWVGVDLKGTTIHMKVVEKNEPEKEKYVSPRNIVAKKKATITRMFVQKGQPMAAIHDHVEKGQLLVSGLIGSEDHQQEVASKAEIYGETWYRSEVTVPLETLFNVYTGKVRTKHKLSFGSLAIPIWGMTFKKEELKHPKTEQEKHSLHFLGFKLPVSYVKEQTRESEEALRKYTKEEAVQEGIKLGKQDVEDKIGENGEVKSEKVLHQTVENGKVKLIILYQVIEDIVQTTPIVRETEE
Atome Classification :
(20 SA)
-----------------------.........10.......-----.----20.----.......----30...-.--....40........--------------50---.......----.----.60.-----.......-----------70----..------.......----------80..---...---------...90..----------....-------..100......-------------.110.......120--..-------------..--...130.----------.-.....140--------.....------------....150..--.-------------------....160......----------------.170.......180...----....190...---..-.-------.200.......210-------.........-----220-------......--.---230-----......--...240..---....------.250-------.......260.......270........280.......290.......300.....--------------..310....---------...320.....----------..330.....--------------....340.-......350.---...-----...360---------........370.......380-------........390......--------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------MKNK
W
L
SFFS
G
K
V
Q
L
E
L
T-----
G
----
R
G
I
----
E
R
L
L
N
E
C
----
T
RQGI-
P
--
V
F
H
V
KKKK
E
A
V
S
L
Y
--------------
I
----
Q
L
Q
D
V
H
A
----
F
----
R
R
V
R
-----
S
K
F
K
C
K
A
-----------
R
-----
F
I------NRKG
F
P
F
----------
L
L
L
K
---SKL---------N
I
G
F
T
I
G
----------
F
A
I
F
-------
F
I
L
L
F
L
LSN
M
V
-------------
W
K
I
D
VTGAKP
E
T
E
H
--
Q
M
-------------
R
Q
--
H
L
N
E
IGV----------K-KG
R
L
Q
F
----------
L
MM
S
P
------------
E
K
I
Q
K
S
L
TN--G-------------------IDN
I
T
W
V
G
V
DLKG----------------
T
T
I
H
M
K
V
VEKNEP
E
K
E
K----YV
S
P
R
N
I
V
A
K
---
K
K
-
A
-------
T
I
T
R
M
F
V
QKGQ
P
---------
M
A
A
I
H
D
H
V
E-----K
G
Q
-------
L
L
V
S
G
L--I---G-------S
E
D
H
Q
Q
--
E
V
A
S
K
A
E
I
---YGE
T
------
W
Y
RS-------EVT
V
P
L
E
T
L
F
N
V
YTGK
V
R
-
T
K
H
KLSFG
S
L
A
I
P
IWG
M
T
F
K
K
E
E
LKHPKT
E
Q
EKH
S
L
H
--------------
F
L
G
F
KL
P
V
S
---------
Y
V
K
E
Q
T
R
E
S
E
E
----------
A
L
R
--
K
Y
T
K
E
--------------
E
A
V
Q
E
G
I
K
-LG
K
Q
D
V
E
D
KI---GEN-----GEV
K
S
----------
E
K
V
L
H
Q
T
VENG
K
V
K
L
I
I
L
Y
Q
--------
V
I
E
D
I
V
QTTPIVRETEE--------------------------------------
47
Fugue
60.29
16%
50
- C6 -
4EXK
2
MALE_ECOLI
A:
[4-478]
A
K
I
E
E
G
K
L
V
I
W
I
N
GDKG
Y
N
G
L
A
E
V
G
K
K
F
E
K
D
T
G
I
K
V
T
V
E
H
P
-----
D
----
K
L
E
----
E
K
F
P
Q
V
A
----
A
T
G
D
G
-
P
D
I
I
F
W
A
H
D
R
F
G
G
Y
A
Q
S
--------------
G
----
L
L
A
E
I
T
P
----
A
----
A
A
F
Q
-----
D
K
L
---------------------------------
Y
P
F
----------
T
W
D
A
---
V
R
Y
---------
N
-
G
K
L
I
A
----------
Y
P
I
A
-------
V
E
A
L
S
L
I
Y
N
K
-----------------
D
L
L
P
N
P
P
K
T
W
E
--
E
I
-------------
P
A
--
L
D
K
E
L
K
A
----------
K
G
K
S
A
L
M
F
NLQEPYFT
W
P
L
I
A
A
D
------------
G
G
Y
A
F
K
Y
A
A
--
G
-------------------
K
Y
D
I
K
D
V
G
V
D
N
A
G
----------------
A
K
A
G
L
T
F
L
V
D
L
I
K
N
K
H
M
----
N
A
D
T
D
Y
S
I
A
E
---
A
A
-
F
-------
N
K
G
E
T
A
M
T
I
N
G
P
---------
W
A
W
S
N
I
D
T
S
-----
A
V
N
-------
Y
G
V
T
V
L
--
P
T
F
K
G
-------
Q
P
S
K
P
F
--
V
G
V
L
S
A
G
I
---
N
A
A
S
------
P
N
K
E
-------
L
A
K
E
F
L
E
N
Y
L
L
T
D
E
G
L
E
A
-
V
N
K
D
K
P
L
G
A
V
A
L
----
K
S
Y
E
E
E
L
A
K
D
P
R
I
A
A
T
M
E
N
A
Q
K
G
EIMPNIPQ
M
S
A
F
W
Y
A
V
R
T
A
V
I
---------
N
A
A
S
G
R
Q
T
V
D
A
----------
A
L
A
--
A
A
Q
T
N
A
-------------
A
A
N
T
P
S
P
D
-
L
T
V
M
S
I
D
K
S
V
LSP
G
E
S
-----
A
T
I
T
T
I
V
--------
K
D
I
D
G
N
P
V
N
E
V
H
I
N
K
T
V
A
R
E
--------
N
L
K
G
L
W
D
Y
G
P
L
K
K
E
N
V
P
G
K
Y
T
Q
V
I
T
Y
RGH
S
N
E
R
I
D
I
S
F
K
Y
AM
S
F
T
K
E
I
S
I
R
G
R
LS
46
Fugue
55.95
19%
19
- C5 -
1ZEL
11
?
A:
[2-297]
--------------------------------
A
M
V
V
S
P
A
G
A
-----
D
----
R
R
I
P
TWA
S
R
V
V
S
G
L
----
A
R
D
R
P
-
V
--
V
--
V
T
K
E
D
L
T
Q
R
L
T
E
A
G-----------
C
----
G
R
D
P
D
S
A
----
I
----
R
E
L
R
R
I
GW
L
V
Q
L
P
V
K
G
-----------
T
-----
W
A
F
IPPGE
A
A
I
S
D
P
Y
----------
L
P
L
R
---
S
W
L
---------
A
R
D
Q
N
A
G
----------
F
-------------
M
L
A
G
A
S
A
A
-------------
W
H
L
G
Y
L
D
R
Q
P
D
--------------------------------------------
G
R
I
P
I
----------
W
L
P
P
A
------------
K
R
L
P
D
G
L
A
S
Y
V
S
-------------------
V
V
R
I
P
W
N
A
A
D
----------------------------------
T
A
----
L
L
A
P
R
---------------------
P
A
L
L
V
R
R
R
L
D
---------
L
V
A
W
----------------------
A
T
G
L
P
A
L
---
G
-------
P
E
A
L
L
V
--
Q
I
A
T
R
P
A
S
---
F
G
P
---------
W
A
-------
D
L
V
P
H
L
D
D
L
V
A
-------------------------
D
C
S
D
E
R
L
E
R
L
L
S
G
R
P
T
S
A
W
Q
--------------
R
A
S
Y
L
L
D
S
G
------------
G
E
P
A
R
G
Q
A
----------
L
L
A
--
K
R
H
T
E
--------------
V
M
-------------------------------------------
P
V
T
R
F
T
T
A
H
S
G
E
S
V
W
A
P
E
Y
Q
--------
L
V
D
E
L
--
V
V
P
L
L
R
V
I
G
K
--------------------------------------
40
Fugue
52.38
18%
45
* C6 *
4XA2
3
?
A:
[1-490]
----------------------------
M
K
I
E
E
G
K
L
V
I
W
I
N
-----
G
DKG
Y
N
G
L
----
A
E
V
G
K
K
F
----
E
K
D
T
G
-
I
--
K
V
T
V
E
H
P
D
K
L
E
E
K
F
--------------
P
----
Q
V
A
A
T
G
D
GPD
I
I
----
F
W
A
H
-----
D
R
F
G
G
Y
A
Q
S
GLL
A
E
I
T
P
A
A
-----
A
F
------
Q
D
K
L
Y
P
F
----------
T
W
D
A
---
V
R
Y
---------
N
-
G
K
L
I
A
----------
Y
P
I
A
-------
V
E
A
L
S
L
I
Y
N
K
-----------------
D
L
L
P
N
P
P
K
T
W
E
--
E
I
-------------
P
A
--
L
D
K
E
L
K
A
----------
K
G
K
S
A
L
M
F
NLQEPYFT
W
P
L
I
A
A
D
------------
G
G
Y
A
F
K
Y
A
A
--
G
-------------------
K
Y
D
I
K
D
V
G
V
D
N
A
G
----------------
A
K
A
G
L
T
F
L
V
D
L
I
K
N
K
H
M
----
N
A
D
T
D
Y
S
I
A
E
---
A
A
-
F
N
K
GETA
M
T
I
N
G
P
W
A
W
S
N
I
D
---------
T
S
A
V
N
Y
G
V
T
V
L
P
TF
K
G
Q
PSKPFVG
V
L
S
A
G
I
--
N
---
A
-------
A
S
P
N
K
E
--
L
A
K
E
F
L
E
N
---
Y
L
L
T
------
D
E
G
L
-------
E
A
V
N
K
D
K
P
L
G
A
V
A
L
K
S
Y
E
-
E
E
L
A
K
D
------
P
R
I
A
A
T
M
E
N
A
Q
K
G
E
I
M
P
N
I
P
Q
M
S
A
F
--------------
W
Y
A
V
R
T
A
V
I
---------
N
A
A
S
G
R
Q
T
V
D
A
----------
A
L
A
--
A
A
Q
T
N
A
A
AA
Y
Q
N
Y
I
A
K
S
Q
V
S
T
G
L
A
D
I
T
-
A
G
K
T
N
A
E
T
K
L
---
A
E
G
LTAAL
T
D
V
E
A
LGLQKSTNAC
S
T
I
T
T
S
I
G
T
N
G
A
S
N
I
T
C
T
L
K
GTSQINS
K
K
I
E
W
I
R
D
A
D
N
A
T
N
G
T
T
G
A
W
R
C
K
T
DVAENLRPKS
C
G
A
S
G
S----------------
43
Fugue
46.72
15%
44
- C1 -
4Z13
10
?
A:
[3-519]
---------------LA
P
I
T
A
P
D
I
T
S
I
C
K
D
A
S
S
G
I
G
N
Q
E
G
A
-----
I
----
R
T
---------
R
K
C
CPPS
L
G
K
K
I
-
K
--
D
F
Q
F
P
N
D
K
K
V
R
M
R
W
--------------
P
AHKG
T
K
K
Q
V
D
D
----
Y
----
R
R
A
I
-----
A
A
M
R
A
L
P
-----------
D
DDPRS
F
V
------
S
Q
A
K
I
H
C
----------
A
Y
C
N
GGY
T
Q
V
---------
D
S
G
F
P
D
I
D
I
Q
IHNSWL
F
F
P
F
H
-------
R
W
Y
L
Y
F
Y
E
R
I
L
G
S
L
I
DEPN
F
A
L
P
Y
W
K
W
D
E
P
K
G
M
P
I
S
N
I
--
F
L
GDASNPLYDQYRD
A
N
--
H
I
E
D
R
I
V
D
LDYDGKDKD
I
-
P
D
Q
Q
Q
V
----------
A
C
N
L
S
------------
T
V
Y
R
D
L
V
R
N
--
G
-------------------
V
D
P
T
S
F
F
G
G
K
Y
V
A
GDSPDP
S
V
G
S
V
E
A
G
S
H
T
A
V
H
R
W
V
G
D
P
T
Q
P
N
N
E
D
MGNF
Y
S
A
G
Y
D
P
V
F
Y
---
I
H
H
A
-------
N
V
D
R
M
W
K
L
W
K
E
L
---------
R
L
P
G
H
V
D
I
T
-----
D
P
D
-------
W
L
N
A
S
Y
--
V
---
F
Y
D
ENK
D
L
V
R
V
Y
N
K
--
D
C
V
N
L
D
K
L
K
Y
N
F
I
E
N
SKEVFP
W
R
N
S
-------
R
P
P
Q
R
R
K
S
A
Q
V
A
T
T
G
D
V
K
-
T
V
E
Q
T
K
F
P
V
R
L
N
Q
I
F
K
V
R
V
K
R
P
A
V
N
R
T
E
E
E
K
D
Q
A
N
E
V
--------------
L
L
I
K
K
I
K
Y
D
SG
K
F
V
K
F
D
V
F
V
N
D
K
L
K
D
G
V
F
TTPCDPEYA
G
G
F
A
--
Q
I
P
H
N
--------------
D
V
M
T
S
T
A
R
-
F
G
L
N
E
L
L
E
D
T
---
N
T
E
-----
G
E
E
Y
A
----------
T
V
T
L
V
P
R
T
G
C
E
D
L
------
T
--------
V
G
E
I
K
I
E
L
V
P
I
P
K
------------------------------------------
45
Fugue
45.70
17%
20
* C5 *
4XMM
-
NU145_YEAST
B:
[92-712]
-----------------D
W
V
E
Q
L
I
L
Y
T
F
A
K
F
S
T
G
S
M
L
L
T
K
D
IVGKS
G
----
V
S
I
----
K
R
L
P
T
E
L
----
Q
R
K
F
L
F
D
--
D
V
Y
L
D
K
E
I
E
K
V
T
I
E
A
R
KSNP
Y
P
Q
I
SESS
L
----
L
F
K
D
A
L
D
----
Y
MEKT
S
S
D
Y
-----
N
L
W
K
L
S
S
-----------
I
-----
L
F
------
D
P
V
S
Y
P
Y
KTDN
D
Q
V
K
M
A
L
L
K
K
---
E
R
H
C
R
L
T
S
W
I
V
S
Q
I
G
P
E
I
E
----------
E
K
I
R
N
SSN
E
I
E
Q
I
F
L
Y
L
L
L
N
D
V
-------------
V
R
A
S
K
L
A
I
E
S
K
N
G
H
--
L
S
-------------
V
L
I
S
Y
L
G
S
N
D
P
----------
R
-
I
R
D
L
A
E
----------
L
Q
L
Q
K
W
S
T
GGCSID
K
N
I
S
K
I
Y
K
L
L
S
G
--
S
PFEGLFSLKELESEFS
W
L
C
L
L
N
L
T
L
C
Y
G
Q
I
D
E
----------------
Y
S
L
E
S
L
V
Q
S
H
L
D
K
F
S
L
P
----
Y
D
D
P
I
G
V
I
F
Q
L
Y
A
A
N
-
E
-------
N
T
E
K
L
Y
K
E
V
R
Q
R
TNALD
V
Q
F
C
W
Y
L
I
Q
T
L
R
F
-----
N
G
T
-------
R
V
F
S
K
E
--
T
---
S
-------
D
E
A
T
F
A
F
A
A
Q
L
E
F
A
Q
L
---
H
G
H
S
------
L
F
V
S
C
F
LND
D
K
A
A
E
D
T
I
K
R
L
V
M
R
E
I
T
L
L
R
A
S
T
N
D
H
I
L
N
R
L
K
I
P
-
S
Q
L
I
F
N
A
Q
A
L
K
D
R
Y
E
G
S
E
V
Q
N
L
L
--------------
D
L
A
E
M
A
I
V
T
S
L-------
V
Q
N
N
E
L
K
T
L
R
E
----------
I
L
N
--
E
F
V
S
I
--------------
N
V
F
E
V
Y
L
K
-
L
V
Q
E
T
I
D
S
L
I
---
S
G
M
-----
K
I
F
Y
V
----------
A
A
C
C
N
V
M
S
Q
E
I
V
S
K
I
L
E
K
N
K
--------
A
K
L
L
E
L
P
L
Q
D
L
M
K
C
T
Y
K
I-------------------------------------
42
Fugue
42.07
12%
-34
- C- -
3V3T
-
?
A:
[1-306]
-----------------------
M
K
N
K
I
V
F
A
P
I
G
----
Q
G
G
-----
G
----
N
I
V
----
D
T
L
L
G
I
C
------
G
D
Y
-
N
--
A
L
F
I
N
T
S
K
K
D
L
D
S
L
--------------
K
----
H
A
K
H
T
Y
H
----
I
----
P
K
E
R
-----
K
K
A
V
G
Y
A
-----------
Q
-----
T
Y
------
Y
K
Q
I
I
A
Q
----------
I
M
E
K
---
F
S
----------------
S
----------
C
D
I
V
-------
I
F
V
A
T
M
A
G
------------------
G
A
G
S
G
I
T
P
P
I
L
G
--
L
A
-------------
K
Q
--
M
Y
P
N
K
H
F
----------
G
-
F
V
G
V
L
P
----------
K
A
T
E
D
------------
I
D
E
H
M
N
A
I
A
--
C
-------------------
W
N
D
I
M
R
S
T
--
N
E
G
----------------
K
D
I
S
I
Y
L
L
D
N
N
K
R
E
K
E
S
----
D
I
--
N
K
E
F
A
T
---
L
F
-
N
-------
D
F
M
N
M
S
E
S
H
A
E
G
VVD------
E
D
E
I
S
K
L
L
T
-----
M
K
K
-------
S
N
V
I
L
E
--
F
---
D
-------
D
K
E
D
I
Q
--
V
A
L
A
K
S
L
K
----
E
S
I
------
F
A
E
Y
-------
T
T
N
T
C
E
F
M
G
I
S
T
T
R
V
V
D
V
-
E
A
I
K
S
I
V
G
Y
P
R
R
T
F
K
G
Y
N
------------
S
K
K
N
I
V
V
--------------
A
T
G
I
E
P
Q
K
T
---------
T
V
Q
M
M
N
E
I
I
E
D
----------
K
M
K
--
Q
R
-------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
36.02
30%
206
- C3 -
5B2T
-
?
B:
[755-845]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
G
R
H
K
P
E
N
---------
I
V
I
E
M
A
R
--------------------
N
S
R
E
RM------------
K
R
I
E
E
G
I
K
E
L
G
S
Q
I
L
K
E
H
P
-----
N
-----
T
Q
L
Q
N
----------
E
K
L
Y
L
Y
Y
L
Q
N
G
R
-----------------------------------------------------------------------
7
PsiBlast_PDB
33.74
30%
200
- C3 -
4UN3
1
CAS9_STRP1
B:
[755-860]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
G
R
H
K
P
E
N
---------
I
V
I
E
M
A
R
--------------------
N
S
R
E
RM------------
K
R
I
E
E
G
I
K
E
L
G
S
Q
I
L
K
E
H
P
---
V
E
N
-----
T
Q
L
Q
N
----------
E
K
L
Y
L
Y
Y
L
Q
N
G
R
-----------------------------------------------------------------------
1
PsiBlast_PDB
33.71
27%
-48
- C3 -
3DR5
-
?
A:
[66-127]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
G
-------
L
V
G
L
Y
I
L
N
G
L
A
-------------
D
N
T
T
L
T
C
I
D
P
E
S
E
H
Q
R
Q
A
-------------
K
A
--
L
F
R
E
A
G
Y
----------
S
-
P
S
R
V
R
F
----------
L
L
S
R
P
------------
L
D
V
M
S
R
L
A
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
33.46
25%
-345
- C4 -
2D5D
-
?
A:
[77-107]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
N
V
V
S
A
P
---
M
P
-
G
-------
K
V
L
R
V
L
----------------
V
R
V
G
D
R
V
R
-----
V
G
Q
-------
G
L
L
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
32.51
30%
209
- C3 -
5B2R
-
?
B:
[755-848]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
G
R
H
K
P
E
N
---------
I
V
I
E
M
A
R
--------------------
N
S
R
E
RM------------
K
R
I
E
E
G
I
K
E
L
G
S
Q
I
L
K
E
H
P
---
V
E
N
-----
T
Q
L
Q
N
----------
E
K
L
Y
L
Y
Y
L
Q
N
G
R
-----------------------------------------------------------------------
30
HHSearch
31.69
21%
-366
- C4 -
1DCZ
-
BCCP_PROFR
A:
[52-84]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
E
G
E
I
P
A
P
---
L
A
-
G
-------
T
V
S
K
I
L
----------------
V
K
E
G
D
T
V
K
-----
A
G
Q
-------
T
V
L
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
31.25
30%
64
- C3 -
5F9R
1
CAS9_STRP1
B:
[751-820]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
G
R
H
K
P
E
N
---------
I
V
I
E
M
A
R
E
N
Q
T
----------
T
Q
K
GQ
K
N
S
R
E
RM------------
K
R
I
E
E
G
I
K
E
L
G
S
Q
I
L
K
E
H
P
---
V
E
N
-----
T
Q
L
Q
N
----------
E
K
L
Y
L
Y
Y
L
Q
N
G
R
-----------------------------------------------------------------------
33
HHSearch
31.02
25%
-387
* C4 *
1BDO
1
A:
[46-77]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
M
M
N
Q
I
E
A
D
---
K
S
-
G
-------
T
V
K
A
I
----------------
L
V
E
S
G
Q
P
V
E
-----
F
D
E
-------
P
L
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
30.63
30%
202
- C3 -
5B2S
-
?
B:
[755-848]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
G
R
H
K
P
E
N
---------
I
V
I
E
M
A
R
--------------------
N
S
R
E
RM------------
K
R
I
E
E
G
I
K
E
L
G
S
Q
I
L
K
E
H
P
---
V
E
N
-----
T
Q
L
Q
N
----------
E
K
L
Y
L
Y
Y
L
Q
N
G
R
-----------------------------------------------------------------------
9
PsiBlast_PDB
30.59
30%
203
- C3 -
4UN5
-
CAS9_STRP1
B:
[755-858]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
G
R
H
K
P
E
N
---------
I
V
I
E
M
A
R
-------------------
K
N
S
R
E
RM------------
K
R
I
E
E
G
I
K
E
L
G
S
Q
I
L
K
E
H
P
---
V
E
N
-----
T
Q
L
Q
N
----------
E
K
L
Y
L
Y
Y
L
Q
N
G
R
-----------------------------------------------------------------------
29
HHSearch
30.43
12%
-269
- C4 -
2JKU
2
A:
[24-55]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
S
S
V
L
R
S
P
---
M
P
-
G
-------
V
V
V
A
V
S
----------------
V
K
P
G
D
A
V
A
-----
E
G
Q
-------
E
I
C
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
30.18
30%
215
- C3 -
4OO8
1
CAS9_STRP1
A:
[755-864]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
G
R
H
K
P
E
N
---------
I
V
I
E
M
A
R
E
N
Q
T
---------------
K
N
S
R
E
R
M
------------
K
R
I
E
E
G
I
K
E
L
G
S
-----------
E
N
-----
T
Q
L
Q
N
----------
E
K
L
Y
L
Y
Y
L
Q
N
G
R
-----------------------------------------------------------------------
15
PsiBlast_PDB
30.13
30%
63
* C3 *
4ZT0
-
CAS9_STRP1
A:
[756-820]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
E
N
---------
I
V
I
E
M
A
R
E
N
Q
T
----------
T
Q
K
G
Q
K
N
S
R
E
R
M
------------
K
R
I
E
E
G
I
K
E
L
G
S
Q
I
L
K
E
H
P
---
V
E
N
-----
T
Q
L
Q
N
----------
E
K
L
Y
L
Y
Y
L
Q
N
G
R
-----------------------------------------------------------------------
10
PsiBlast_PDB
30.04
30%
192
- C3 -
5FQ5
-
?
B:
[755-852]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
G
R
H
K
P
E
N
---------
I
V
I
E
M
A
R
E
------------------
K
N
S
R
E
RM------------
K
R
I
E
E
G
I
K
E
L
G
S
Q
I
L
K
E
H
P
---
V
E
N
-----
T
Q
L
Q
N
----------
E
K
L
Y
L
Y
Y
L
Q
N
G
R
-----------------------------------------------------------------------