@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu26030: (2016-07-11 )
MAKLTATFELHDKISRKLRMIQGNAERLKRAANGPLIFEAEDRTERVMRQIDRSANRLTARARLLEMGLDDRVSNGLHSIRQQAEDLTEGSHEVTVSVNDQATPRFRLIRGGLTDLNSSHAEPTVSVRDHASNQLDEIRRHVTDVDSEHAEPTVSIKDRASAALDAIEAKIDSLKGATITLAVAGGFSAGSIMGSGKSTMSQDAYVSATSNVNKKDVAKMTDQIYFNNKAGSSREEVSLSLRNLSQQTGASKKALAELTESSSKIAQLMNADQAEVDRAFSSMYNNLKLSGKQSGDLIAYVYRNAGDQADDLLDTMNEYSSTFKDLKLTGGQIANAMIKGTKGGARNFDNLADSMREFNIRRTEMSDSQVDAFKTLFGAKETKKMFKGFKDGSISGEESLFRVAKALSKVKDKTKRAAIATELIGTQYEDLKQPILDMAEGIGTSAKTSGELERSFTKLRDNNPMTPVNDAMRDFESISKDMGTSLLTGLGPAFDKISSFINSKEGQEKLKEIKKDIADLGEEIGDKLNVAIEWSVNHWDDLKTAIKVVIPSLIGLIGYLKILRPLLKGIGTVGSDAAGVIRKLIPKRTPKAGTNTQSERRNRNSNRNASTRGRESKTATGPTSLPRSGSLTYCCCSDGGKNDRIRRRRGKRVLGRRGNPNRMNPSDSSIAVSSERLERRRSGRTVGTNPTRDSRSAIITTRSELYSAGRAAGGTSKFGKVLSPLKSVGKFAKGVPLLGTALAATDLIGMNKDNVGEKIGSAGGGLAGAATGAAIGSVIPGVGTAIGGLVGGIAGTMGGSSLGKAFDGSEVKKKLNSTLFDQKWWSEKWSGIKSNAKTSINGLSDTWSNVKEKVKSTLFNSEWWSEKWSGVKSWAQNKWNSASSVWESVKGKIKSTLFSEKWWSGKWEGVKSWAQSKWDSASSVWQSVKGKLKSTLFSEKWWSGKWESVKSWSKNKWDNAKSIWKSVKSSISETLFSKKWWSEKWQSVKELGSSILGGVKEVGGKVASSAKKTAGKAWGYVKSGVNYLFGSGKEKPKKHATGGYITKPTISWIGEAGKEFVIPVENNKGRGKMLLSQAASKLGMSVVDDIASASSAGGEPATSPLVRSAAVTASVSPIIDTSSLDEQATSFGQQFTKSFDQGIRDNVVSMEAWKQKNVGQPMNNLISYSPNYGKQVVNGYAKGQNSTSTGTDGFLQTKVKMPFQNTVNKSSSWGSGTIKGFASGQNSSQTGTDQYVSTHINKPFIRSKESSNGWGSGMIGNFVSGMTSKASEVNEAAKELAKKVEKAFREELDIHSPSRVMMSLGRFASIGIVKGLDSVDVKKFAEKQAGSLAAAYSGMGAVSGNVKQWLMAAIMATKTPMSWLPGLMTIAQHESGGNPKAINLWDSNAKAGHPSQGLMQTIPSTFNAHKLPGMNNILNPIHNAAAAIGYIKSRYGSINNVPGIRSMRHGGPYVGYANGGLITKEQIARVGEGNKREWIIPEERGIRGRYLLAQAAKALGMEVTDPSEKGQTELSSGQVTAATTGRNQTTFKAAGGKEVIIQFNGDQHFHNDQDMNSLVAKIKQALVDELEQDINIGTKGVVAFD
Atome Classification :
(20 SA)
.........10........20........30........40..------......50........60........70....-----....80.......----.90........100.......110.......120-.......--..130.......140.......150.......160----.......170.......180.......190.-----......200.......210.......220........230.......240.......250.......260----........270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390......-.400.......410.......------420-........430.......440.......450.......460.......--------470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570--.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.----......680.......690.......700.......710.......720..---.....730.---......740.......750.......760.......770.......780.....---..790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890..-.....900.......910.......920.......930.......940..--.....950.......960........970.......980.......990.......1000......1010......1020......1030......1040......1050......1060......1070......1080......1090......1100......1110......1120......1130......1140......1150......1160......1170......1180......1190......1200......1210......1220......1230......1240......1250......1260......1270......1280......1290......1300......1310......1320......1330......1340......1350......1360---......1370......1380.-----------------------------------.....1390........1400...-----...1410--..---.----.--.---..-..1420...----...1430--..-.....1440......1450......1460......1470......1480......1490......1500......1510......1520......1530......1540......1550......1560......1570......1580..
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MA
K
L
T
A
T
F
E
L
H
D
K
I
S
R
K
L
R
M
IQG
N
A
E
R
L
K
R
AANG
P
L
I
F
EAE
D
R
------
T
E
R
V
M
R
Q
I
D
R
S
A
N
R
L
T
A
R
A
R
L
L
E
MGL
D
D
R
V
S
N
-----
G
L
H
S
I
R
Q
Q
A
E
D
LT----EGS
H
E
V
T
V
SVNDQAT
P
R
F
R
L
I
RGGLTDLNSSH---AEP
T
V
S
V--RDHAS
N
Q
L
D
E
I
R
R
H
V
TDVDSEHAEP
T
V
S
I
K
D
R
A
S
A
----
A
L
D
A
I
E
A
K
I
D
SLKG
A
T
I
T
L
A
V
AGGFSAG
S
I
M-----GSGKSTMSQ
D
A
Y
V
SATSNV
N
K
K
D
V
A
K
M
-
T
D
Q
I
Y
FNNKAGS
S
R
E
E
V
S
L
S
L
R
N
L
S
Q
QTGA
S
K
K
A
L
A
E
L
T
E
S
-----
S
S
K
I
A
Q
L
MNA
D
Q
A
E
V
D
R
A
F
S
S
M
YN
N
L
K
LSGKQSG
D
L
I
A
Y
V
YRNAGD
Q
A
D
D
L
L
D
T
M
N
E
Y
S
S
T
F
K
D
L
KLTG
G
Q
I
A
N
A
M
IKGTKGGAR
N
F
D
N
L
A
D
S
M
R
E
FN
I
R
RTEMSD
S
Q
V
D
A
F
K
T
L
FG
A
K
E
T
K
K
M
F
K
GFKDGSIS
G
E
E
-
S
L
F
R
V
A
K
A
L
S
K
V
K
D
K
T
K
R
A
A
I
------
A
T
--
E
L
IG
T
Q
Y
E
D
L
K
Q
P
I
L
D
M
A
E
GIGTSAKTS
G
E
L
E
R
S
F
T
K
LRDNNPMT
P
V
N
--------
D
A
M
R
D
F
E
S
I
S
K
D
M
G
T
S
L
L
TGL
G
P
A
F
D
K
I
S
S
F
I
N
S
K
E
G
Q
E
K
L
K
E
I
K
K
D
I
A
D
L
G
E
E
IGDK
L
N
V
A
I
E
W
SVN
H
W
D
D
L
K
T
A
I
K
V
V
I
P
S
L
I
G
L
I
G
Y
L
K
I
L
R
P
L
L
K
G
IGT--VGS
D
A
A
G
V
I
R
K
LIPKRTPKAGTN
T
Q
S
E
RRNRNSNRNASTRGRESKTATGPTSLPRSG
S
L
T
Y
C
CCSDGGK
N
D
R
I
R
R
R
R
G
K
R
V
LGRRGNPNRMNPSDSSI
A
V
S
----
S
E
R
L
E
R
R
RSGRTVGTNPTRDSR
S
A
I
I
T
T
R
S
E
L
Y
SAGRAAGG
T
S
K
F
G
K
V
L
S
P
---
L
K
S
V
G
K
F
AK---GVPLL
G
T
A
L
A
A
T
D
LIGMNK
D
N
V
G
E
K
IGSAGGGLAG
A
A
T
G
A
A
I
G
S
VIP
G
V
G
T
A
I
G
---
G
L
V
G
G
I
A
GTMGG
S
S
LGKAF
D
G
S
E
V
K
K
K
L
N
S
T
L
F
D
Q
K
W
W
S
E
K
WSGIKSNAKTSINGL
S
D
T
W
S
N
V
K
E
K
V
K
S
T
LFN
S
E
W
W
S
E
K
W
S
G
V
K
S
W
A
QNKWN
S
A
S
S
V
W
E
S
V
K
G
K
I
K
-
S
T
L
FSEKWWSG
K
W
E
G
V
K
S
W
A
Q
SKWD
S
A
S
S
V
W
Q
S
V
K
G
K
L
K
S
T
L
FSEKWWSG--K
W
E
S
V
K
SWSKNKWD
N
A
-
K
S
I
W
K
S
V
K
S
S
I
S
E
T
L
F
S
K
K
W
W
S
E
K
W
Q
S
V
K
E
L
G
S
S
I
L
G
G
V
K
E
V
G
G
K
V
A
S
S
A
K
KTAG
K
A
W
G
Y
V
K
S
G
V
N
Y
L
FGSGKEKPKKHATGGYITK
P
T
I
S
W
I
G
EAG
K
E
F
V
I
P
VENNKGR
G
K
M
L
L
S
Q
A
A
S
KL
G
M
S
V
V
D
D
I
A
SASSAGGEPAT
S
P
L
V
R
S
AAVTASVSPIIDT
S
S
L
D
E
Q
A
T
S
F
G
Q
Q
F
T
K
S
F
D
Q
G
I
R
DN
V
V
S
M
E
A
W
K
QKNVGQ
P
M
N
N
L
ISYSPNY
G
K
Q
V
V
N
G
YAKGQNSTSTGTDG
F
L
Q
T
K
V
KMP
F
Q
NTVNKSSSWGSG
T
I
K
G
FASGQNSSQTG
T
D
Q
Y
V
S
T
HINKPFIRSKESSNGWGS
G
M
I
G
N
F
V
S
G
M
T
S
K
A
S
E
V
N
E
A
A
K
E
L
A
K
K
V
E
K
A
F
R
E
ELDIH
S
P
S
R
V
M
M
S
L
G
R
F
A
S
I
G
I
VKGL
D
S
V
D
V
K
K
F
A
E
K
QA
G
S
L
A
A
A
Y
SGMGAVSG
N
V
K
Q
W
L
M
A
A
I
M
ATKT
P
M
S
W
---
L
P
G
L
M
T
I
A
QHESGGNP
K
A
I
N
L-----------------------------------WDSNAK--AGHPSQ
G
L
M
Q
T
I
P
S
TF-----NAHK-----LP---
G
----
M
--
N
---
N
I
-
L
N
P
I
H
N
A
A
A
----
A
I
G
Y
I
K
---
S
R-YGSINNVPGIRSMRHGGP
Y
V
G
YANGGLI
T
K
E
Q
I
A
R
VGEGNKR
E
W
IIPEERGIR
G
R
Y
L
L
A
Q
A
A
K
ALGMEVTDPSEKGQTELSSG
Q
V
T
A
A
TTGRN
Q
T
T
F
KAAGG
K
E
V
I
I
Q
FNGDQHFH
N
D
Q
D
M
N
S
L
V
A
K
I
K
Q
A
L
V
D
E
L
E
Q
DINIGTK
G
V
V
AFD
28
Fugue
53.82
15%
42
- C2 -
3UGM
-
PTHX1_XANOP
A:
[169-1048]
K
P
K
V
R
E
L
V
A
H
I
V
A
L
S
Q
H
P
A
A
L
G
T
V
A
V
T
Y
Q
H
I
I
T
A
L
A
T
H
E
D
I
V
G
V
G
KQWS
G
A
R
A
L
E
A
L
L
T
D
A
G
E
L
R
G
P
P
L
Q
L
D
T
G
Q
L
V
K
I
A
K
R
GG
V
T
A
M
E
A
V
H
A
S
R
N
A
L
T
PLNL
T
P
A
Q
V
V
A
I
A
S
N
N
G
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
A
H
GLT
P
A
Q
V
V
A
I
A
S
H
D
G
G
K
Q
A
L
E
T
M
Q
R
L
L
P
V
L
C
Q
A
H
G
L
P
P
D
Q
V
V
A
I
A
S
N
----
I
--
G
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
A
H
G
L
T
P
D
Q
V
V
A
I
A
SH
G
G
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
A
H
G
L
T
P
D
Q
-
V
V
A
I
A
S
H
D
G
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
A
H
G
L
T
P
D
Q
V
V
A
I
A
S
--------------
N
G
G
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
A
H
G
L
T
P
D
Q
V
V
A
I
A
S
N
G
G
K
Q
A
L
E
T
V
Q
R
L
--
L
P
V
L
C
Q
A
H
G
L
T
P
D
Q
V
V
A
I
A
S
H
--
D
G
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
-
Q
T
H
G
L
T
P
A
Q
V
V
A
I
A
S
H
D
G
G
K
Q
A
L
E
T
V
Q
Q
L
L
P
V
L
C
Q
A
H
G
L
T
P
D
Q
V
V
A
I
A
S
N
I
G
G
K
Q
A
L
A
T
V
------
Q
R
LL
P
V
L
C
Q
A
H
G
L
T
P
D
Q
V
V
A
I
A
S
N
-
G
G
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
A
H
G
L
T
P
D
Q
V
V
A
I
A
SNG
G
G
K
Q
A
L
E
T
V
Q
R
L
L
-
P
V
L
C
Q
A
H
G
L
T
Q
V
Q
V
V
A
I
A
S
N
I
G
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
A
H
G
--
L
T
P
A
Q
V
V
A
I
A
S
H
D
G
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
A
H
G
L
T
P
D
Q
V
V
A
I
A
S
NG
G
G
K
Q
A
L
E
T
V
Q
R
L
L
P
G
L
T
Q
E
Q
V
V
A
I
A
S
---
N
N
G
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
A
H
G
L
T
P
D
Q
V
V
A
I
A
--
S
N
G
G
G
K
Q
A
L
E
T
V
Q
--
R
L
L
P
V
L
C
Q
A
H
G
L
T
P
A
Q
V
V
A
I
A
S
NIG
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
D
H
G
L
T
L
A
Q
V
V
A
I
A
S
N
I
-
G
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
GLT
Q
D
Q
V
V
A
I
A
S
NIG
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
D
H
G
L
T
P
D
Q
V
V
A
I
A
S
N
I
G
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
D
H
G
LT
L
D
Q
V
V
A
I
A
S
N
G
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
D
H
G
L
T
P
D
Q
V
V
A
I
A
S
N
S
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
45.32
24%
34
- C5 -
3VHL
1
A:
[130-278]
---------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
H
E
Q
H
R
R
N
T
V
L
T
T
M
H
A
F
P
Y
I
K
T
R
I
R
V
S
Q
K
E
E
F
V
L
T
P
I
E
V
A
I
E
D
M
K
K
K
T
L
Q
L
A
V
A
---
T
H
Q
E
P
P
-----
D
A
K
M
L
Q
M
V
L
Q
G
S
V
G
A
T
V
N
Q
G
P
L
E
V
A
Q
V
F
L
A
E
I
P
A
D
P
K
L
Y
R
H
H
N
K
L
R
L
C
F
K
E
F
I
M
R
C
G
----------
E
A
-----
V
E
K
N
R
R
L
I
T
A
E
Q
R
E
Y
Q
Q
E
L
K
K
N
Y
N
K
L
R
D
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
HHSearch
45.12
22%
-63
- C4 -
4P0G
3
MLTF_PSEAE
A:
[268-339]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
H
F
K
Q
S
G
K
Q
L
D
T
D
W
R
L
------
L
A
A
I
G
Y
Q
E
S
L
W
Q
P
G
A
T
S
K
---------------------------------------------
T
G
V
R
G
L
M
M
L
T
N
R
T
A
-----
Q
A
M
G
-----
V
------------
S
---
N
R
-
L
D
P
K
Q
S
I
Q
G
----
G
S
K
Y
F
V
---
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
45.03
22%
-69
- C4 -
4CFP
2
MLTC_ECOLI
A:
[178-265]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
R
Q
A
S
R
K
Y
G
V
D
E
S
L
------
I
L
A
I
M
Q
T
Q
S
S
F
N
P
Y
A
V
S
---------------------------------------------
R
S
D
A
L
G
L
M
Q
V
V
Q
H
T
A
-----
G
K
D
V
F
R
S
Q
G
K
S
G
T
P
S
----
R
--
S
---
F
L
-
F
D
P
A
S
N
I
D
T
----
G
T
A
Y
L
A
M
L
N
N
V
-
Y
L
G
----------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
43.44
26%
-26
- C4 -
4HJZ
1
EMTA_ECOLI
A:
[46-127]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
Q
K
A
G
A
A
W
G
V
D
P
Q
L
------
I
T
A
I
I
A
I
Q
S
G
G
N
P
N
A
V
S
---------------------------------------------
K
S
N
A
I
G
L
M
Q
L
K
A
S
T
S
G
R
D
V
Y
R
R
M
G
-----
W
S
G
E
P
T
----
T
--
S
---
E
L
-
K
N
P
E
R
N
I
S
M
----
G
A
A
Y
L
N
---
I
L
--------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
42.81
19%
-56
- C4 -
4XP8
-
?
A:
[21-103]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
I
T
G
K
A
Y
N
I
D
P
L
I
------
L
K
A
I
A
W
N
E
S
K
N
K
N
G
I
K
S
K
-----------------------------------
I
---
N
K
--
N
G
T
Y
N
I
G
I
M
Q
I
N
S
S
H
L
-----
D
L
L
S
-----
K
F
---
N
----
I
S
E
D
---
D
L
L
N
D
A
C
I
N
I
S
V
----
A
G
Y
I
L
A
---
S
N
-
I
------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
42.37
17%
3
- C4 -
1QUS
3
MLTB_ECOLI
A:
[102-223]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
N
R
A
W
Q
V
Y
G
V
P
P
E
I
------
I
V
G
I
I
G
V
E
T
R
W
G
R
V
M
G
K
T
R
I
L
D
A
L
A
T
L
S
F
NYPRR
A
E
Y
F
S
G
E
L
E
T
F
L
L
M
A
R
D
E
Q
D
D
P
L
N
L
K
G
S
F
A
G
A
M
G
Y
G
Q
F
M
P
S
S
Y
-----
K
Q
Y
A
-----
V
D
---
F
SGDG
H
--
I
---
N
L
-
W
D
P
V
D
A
I
G
S
----
V
A
N
Y
F
K
---
A
---------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
41.33
13%
-18
- C5 -
4U5A
-
?
A:
[48-240]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
N
I
I
E
E
F
D
K
L
S
D
D
F
S
N
D
I
N
A
T
K
Q
T
I
K
D
L
F
L
D
I
-
E
A
S
D
D
V
V
K
L
L
S
K
Y
S
F
V
P
E
E
K
L
N
I
I
D
G
I
L
R
S
F
I
E
N
N
K
T
H
V
I
N
S
S
N
A
Y
I
Y
I
Q
K
E
K
I
K
N
--
V
C
N
F
I
L
K
K
L
N
S
L
I
Q
I
N
E
L
N
K
S
H
I
I
L
K
Y
G
K
G
E
A
K
K
-
G
V
L
E
S
I
K
N
N
D
D
I
S
K
N
L
K
S
E
L
L
KYR
V
S
E
L
I
--
N
F
I
T
P
I
Y
D
D
F
I
K
N
L
T
D
L
I
N
D
L
Q
I
K
L
K
N
I
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
40.36
22%
-42
- C4 -
5E27
-
RPFB_MYCTU
A:
[284-350]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
W
D
A
I
A
G
C
E
A
G
G
N
W
A
I
N
T
---------------------------------------------
G
N
G
Y
Y
G
G
V
Q
F
D
Q
G
T
W
-----
E
A
N
G
-----
G
L
---
R
----
Y
--
A
PRA
D
L
-
A
T
R
E
E
Q
I
A
V
----
A
E
V
T
R
L
---
R
Q
G
W
G
-----------------------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
39.01
14%
-30
- C5 -
4OYD
-
?
B:
[1-117]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
P
K
K
V
L
D
K
------
A
K
--
D
Q
A
E
N
R
V
R
E
L
K
Q
K
L
E
E
L
Y
K
E
A
-
R
K
L
D
L
T
Q
E
M
R
R
K
L
E
L
R
Y
I
A
A
M
L
M
A
I
G
--------
D
I
Y
N
A
I
R
Q
A
K
Q
E
A
D
K
L
K
K
A
G
L
-------
V
N
S
Q
Q
L
D
E
L
K
R
R
L
E
E
L
K
E
E
A
S
R
K
A
R
D
Y
G
R
E
F
Q
L
K
L
E
Y
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
38.64
23%
-22
- C4 -
4CGE
-
RPFE_MYCTU
A:
[101-160]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
D
A
I
A
Q
C
E
S
G
G
N
W
S
I
N
T
G
---------------------------------------------
N
G
Y
Y
G
G
L
R
F
T
A
G
T
W
-----
R
A
N
G
-----
G
S
---
G
----
S
--
A
---
A
N
-
A
S
R
E
E
Q
I
R
V
----
A
E
N
V
L
R
---
S
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
38.15
14%
-82
- C4 -
1GBS
-
LYG_CYGAT
A:
[52-124]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
K
K
V
G
E
K
L
C
V
E
P
A
V
------
I
A
G
I
I
S
R
E
S
H
A
G
K
V
L
K
N
G
-----------------------------------
W
G
------
D
R
G
N
G
F
G
L
M
Q
V
D
K
R
S
H
-----
K
P
Q
G
-----------------------
T
-
W
N
G
E
V
H
I
T
Q
----
G
T
T
I
L
T
---
D
F
-
I
------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
38.15
22%
-39
- C4 -
4EMN
3
RPFB_MYCTU
A:
[4-66]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
D
A
I
A
G
C
E
A
G
G
N
W
A
I
N
T
---------------------------------------------
G
N
G
Y
Y
G
G
V
Q
F
D
Q
G
T
W
-----
E
A
N
G
-----
G
L
---
R
----
Y
--
A
PRA
D
L
-
A
T
R
E
E
Q
I
A
V
----
A
E
V
T
R
L
---
R
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
37.90
11%
-91
- C4 -
4G9S
1
?
A:
[54-125]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
T
R
V
G
Q
K
H
G
L
D
P
A
I
------
I
A
G
I
I
S
R
E
S
R
A
G
S
A
L
D
H
G
-----------------------------------
W
----
G
--
D
H
G
K
G
F
G
L
M
Q
V
D
K
R
Y
H
-----
K
I
V
-----------------------
G
A
-
W
D
S
E
K
H
I
S
Q
----
G
T
E
I
L
I
---
E
F
--------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
34.67
28%
-13
- C4 -
4OW1
1
RPFC_MYCTU
A:
[6-65]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
D
A
V
A
Q
C
E
S
G
G
N
W
A
A
N
T
---------------------------------------------
G
N
G
K
Y
G
G
L
Q
F
K
P
A
T
W
-----
A
A
F
G
-----
G
V
---
G
----
N
--
P
---
A
A
-
A
S
R
E
Q
Q
I
A
V
----
A
N
R
V
L
A
---
E
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
33.19
19%
1
- C4 -
2VB1
12
LYSC_CHICK
A:
[10-95]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
M
K
R
H
G
L
D
N
Y
R
GYS
L
G
N
W
V
C
A
A
K
F
E
S
N
F
N
T
Q
A
T
N
R
-----------------------------------
N
----
T
--
D
G
S
T
D
Y
G
I
L
Q
I
N
S
R
W
W
-----
C
N
D
G
-----
R
T
---
P
GS--
R
--
N
---
L
C
-
N
I
P
C
S
A
L
L
S
SDI
T
A
S
V
N
C
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
33.02
21%
57
- C5 -
4O94
1
?
A:
[203-320]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
V
D
G
Q
E
N
T
W
S
N
I
-----------------------
F
S
Q
K
F
Y
E
V
Q
K
D
I
T
E
S
D
H
G
V
I
D
Y
M
V
V
V
N
A
K
W
W
N
G
L
S
K
D
L
Q
D
A
M
K
K
A
M
D
E
A
T
K
V
N
N
D
V
A
G
K
L
N
D
E
A
K
Q
K
I
A
S
S
G
A
S
K
I
H
Q
L
T
P
E
Q
R
K
Q
W
V
E
A
M
K
P
V
W
A
K
F
E
S
A
I
G
K
D
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
32.83
28%
28
- C4 -
1JUG
-
LYSC1_TACAC
A:
[26-68]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
N
W
V
C
T
A
F
H
E
S
S
Y
N
T
R
A
T
N
H
--------------------------------------
N
-
T
--
D
G
S
T
D
Y
G
I
L
Q
I
N
S
R
Y
W
-----
C
H
D
G
-----
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
32.16
24%
4
- C4 -
2NWD
-
LYSC_HUMAN
X:
[25-69]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
N
W
M
C
L
A
K
W
E
S
G
Y
N
T
R
A
T
N
Y
-----------------------------------
N
A
---
G
--
D
R
S
T
D
Y
G
I
F
Q
I
N
S
R
Y
W
-----
C
N
D
G
-----
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
32.08
18%
66
- C5 -
1FX7
3
IDER_MYCTU
A:
[1-64]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
E
L
V
D
T
T
E
M
Y
L
R
T
I
Y
D
L
E
E
E
GVTPL
R
A
R
I
A
E
R
L
D
Q
S
G
P
T
V
S
Q
T
V
S
R
M
E
R
D
G
L
L
R
V
A
G
D
R
H
L
E
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------