@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu26620: (2016-07-11 )
MKKGQLFIGALTCLVASMSWGAMFPVADHALEFVDPFYFSFIRYGVVTIMLVILLLVREGKKSFHLEGKAKWIILFGVMAFTIYNVLIFLGQRLMGKSGIMTASIAEALMPMLSIVILWGYKHVKPKKYTMISILIAFLGASMVITKGNISFFFSLGDHLFSILFIFIGVLGWVVYTMGGQIFREWSTLRYSTLTCLFGTAITGIMTAILTAQGYVSVPSIKVIAAIKYDFLFMITLPGIIALLSWNYGIKILSSINGILFINFVPITTLLIMVIKGYNITAFDIVGTLFVIIGLILNNIYQRKEDYKQVLQKEKTNLTIT
Atome Classification :
(18 SA)
--------------------------------------------------------------------------------.........10........20..-......30....----------------...-.40.-.-...-...-----50------........-.60-.--........70........80........90......--..100..-....------------.-110--.-------........120...-...--.130.......140-----......--.150.......160--------------.......170.---...--...180..-.--....--190........200.-.-.....210.......220..----.....230-----..-----.......------240.......-250---.-...-....-----.260.------.......-270-----.--.-------------------..-.....280...--------....290--------------...--.....300.......310.......320-----------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------------------------------------------------------------MKKG
Q
L
F
I
G
A
L
T
C
L
V
A
SMSWGAM-F
P
V
A
D
H
A
L
E
F
V
D
----------------
P
F
Y
-
F
S
F
I
-
R
-
Y
G
V
-
V
T
I
-----
M
-------
L
V
I
L
L
L
V
R-EG--K--K
S
F
H
LEG
K
A
K
W
I
I
L
F
G
V
M
A
F
T
I
Y
N
V
L
I
F
L
G
Q
R
L
MGK--SGI
M
T
A
S
-
I
A
E
A
------------
L
-
M
----
P
-------
M
L
S
I
V
I
L
WGYKHVK-P
K
K
--
Y
T
M
I
S
I
L
I
A
F
LGA
S
-----
M
V
I
T
KG--
N
I
S
F
F
F
S
L
G
D
H
L
F
S
--------------
I
L
F
I
F
I
G
V
L
G
W
---
V
V
Y
--TM
G
G
Q
I
F
R
-
E
--
W
S
T
L
--
R
Y
-
S
T
L
T
C
L
F
G
T
A
I
T
-
G
-
I
M
T
A
I
L
TAQG
Y
V
SVP
S
I
K
V
I
----
A
A
I
K
Y
D
-------
F
L
-----
F
M
I
T
L
P
G
------
I
I
A
L
L
SWN
Y
G
-
I
-----
K
-
I
L
S
-SIN
G
-----
I
L
-
F
I
------
N
F
V
P
I
T
T
-
L
-------
L
--
I
-------------------
M
V
-IKGY
N
I
T
A
F
D
I
--------
V
G
T
L
F
V
---------------
I
I
G
--
L
I
L
N
N
I
Y
Q
R
K
E
D
Y
K
Q
V
L
Q
K
EKTNLTIT------------
18
Fugue
69.37
18%
-60
- C2 -
4D08
3
PDE2A_HUMAN
A:
[4-342]
-------------------------------------------------------------------------D
D
E
Y
T
K
L
L
H
D
G
I
Q
P
V
A
A
I
D
S
N
F
A
S
F
T
Y
T
P
R
S
L
P
E
D
D
T
S
M
A
I
L
S
----------------
M
L
Q
D
M
N
F
I
-
N
N
Y
K
I
D
C
P
T
-----
L
-------
A
R
F
C
L
M
V
K
-
K
G
YR
D
--
P
P
Y
H
-----
N
W
M
H
A
F
S
V
S
H
F
C
Y
L
L
Y
K
N
L
-----------
E
L
T
N
Y
L
-
E
D
I
E
------------
I
-
F
----
A
-------
L
F
I
S
C
M
C
H
D
L
D
H
R
G
-
T
N
N
--
S
F
Q
V
A
-------
S
K
-----
S
V
L
A
A
L
--
Y
S
S
E
G
S
V
M
E
R
H
H
F
A
--------------
Q
A
I
A
I
L
N
------------
T
H
G
C
N
I
F
D
-
H
--
F
S
R
K
--
D
Y
-
Q
R
M
L
D
L
M
R
D
I
I
L
------
A
T
D
L
A
H
H
L
R
I
F
K
D
L
Q
K
M
----
A
E
V
G
Y
D
RNN
K
Q
H
H
R
L
-----
L
L
C
L
L
M
T
------
S
C
D
L
S
D
Q
T
K
G
-
W
-----
K
-
T
T
R
-
K
I
A
E
-----
L
I
-
Y
K
------
E
F
F
S
Q
G
D
-
L
-------
E
--
K
A
M
GNRPMEMMDREKAY
I
P
E
L
Q
-
I
S
F
M
E
H
I
A
M
P
I
--------
Y
K
L
L
Q
D
---------------
L
F
---
P
K
A
A
E
L
Y
E
R
V
A
S
N
R
E
H
W
T
K
V
S
H
K
F
T
I
R
GLPSNNSLDFLD
20
Fugue
68.94
17%
-52
- C1 -
4Q0W
4
RAD2_YEAST
A:
[1-362]
-----------------------------------------------------------------------------------------------------
G
V
-
H
S
F
W
D
I
A
G
P
T
A
R
----------------
P
V
R
-
L
E
S
L
-
E
-
D
K
R
-
M
A
V
DASI
W
I
-------
Y
Q
F
L
K
A
V
R
-
D
Q
--
N
AV
K
N
S
H
I
T
G
F
F
R
R
I
C
K
L
--
L
Y
F
G
I
R
P
V
F
V
F
D
G
G
V
P
V
L
K
--
R
E
T
I
R
Q
R
-
K
E
R
R
Q
G
K
R
EDEVT
M
D
M
I
-
K
----
E
-------
V
Q
E
L
L
S
R
F
G
I
P
Y
I
T
-
A
P
M
E
A
E
A
Q
C
A
E
L
L
Q
L
N
L
V
D
-----
G
I
I
T
D
D
--
S
D
V
F
L
F
G
-
G
T
K
I
Y
K
--------------
N
M
F
---
H
E
K
N
Y
---
V
E
F
--
Y
D
A
E
S
I
L
K
-
L
LG
L
D
R
K
--
N
M
-
I
E
L
A
Q
L
L
G
S
D
Y
T
-
N
-
G
L
------
K
G
M
G
P
V
S
S
I
E
V
I
----
A
E
F
G
N
----------------
L
K
N
F
K
D
------
W
Y
N
N
G
Q
F
D
K
R
-
K
Q
E
T
EN
K
-
F
E
K
-
D
L
R
K
-----
K
L
-
V
N
------
N
E
I
I
L
D
D
-
D
-------
F
PS
V
-------------------
M
V
-
Y
D
A
Y
M
R
P
E
V
D
H
DT
T
P
F
V
W
G
V
P
D
L
D
M
---------------
L
R
S
--
F
M
K
T
Q
L
G
W
P
H
E
K
S
D
E
I
L
I
P
L
I
------------------
16
Fugue
62.16
20%
-69
- C2 -
4O2X
-
MALE_ECOLI
A:
[5-483]
EG
K
L
V
I
W
I
N
GDKG
Y
N
G
L
A
E
V
G
K
K
F
E
K
D
TG
I
K
V
T
V
E
H
P
D
K
L
E
E
K
F
P
Q
V
A
A
T
GDGPD
I
I
F
W
A
HDR
F
G
G
Y
A
Q
S
GLL
A
E
I
T
P
D
K
A
F
Q
D
K
L
Y
P
F
T
W
D
A
V
R
Y
N
G
K
L
I
A
--
Y
P
I
A
V
E
A
L
S
L
I
Y
N
KDLLPNPPKTWEE
I
P
A
L
D
-
K
E
L
K
-
A
-
K
G
K
-
S
A
L
-----
M
FNLQEPY
F
T
W
P
L
I
A
A
-
D
G
--
G
--
Y
A
F
K
Y
E
N
G
K
Y
D
I
K
D
V
G
V
D
N
A
G
A
K
A
G
L
T
F
L
V
D
L
I
K
N
K
HM
N
A
D
T
D
Y
S
-
I
A
E
A
------------
A
-
F
N
K
GE
T
-------
A
M
T
I
N
G
P
W
A
W
S
N
I
D
T
S
K
V
--
N
Y
G
V
T
V
L
P
T
F
K
G
Q
P
SK
P
F
V
G
V
L
S
A
G
I
N
A
A
S
P
N
K
E
L
A
K
E
F
L
E
--------------
N
Y
L
L
T
D
E
G
L
E
A
---
V
N
K
D
K
P
L
G
A
V
A
L
K
-
S
--
Y
E
E
E
L
A
K
D
-
P
R
I
A
A
T
M
E
N
A
Q
K
-
G
E
I
M
P
N
I
P
Q
M
S
A
F
W
Y
A
V
R
T
A
V
I
----
N
A
A
S
G
R
-------
Q
T
-----
V
D
E
A
L
A
A
------
A
Q
T
N
A
A
A
N
L
E
K
I
-----
K
-
K
L
R
-
N
V
I
T
SA
W
K
V
I
L
-
Y
N
D
DIH--
N
F
T
Y
V
T
D
-
V
-------
I
--
V
-------------------
K
V
-
V
G
Q
I
S
K
A
K
A
H
T
--------
I
T
V
E
A
H
---------------
S
T
G
QA
L
I
L
S
T
W
K
S
K
A
E
K
Y
C
Q
E
L
Q
Q
N
G
L
T
V
S
I
I
H
ES---------
14
Fugue
55.96
18%
-59
- C2 -
4DIM
-
?
A:
[3-400]
--------------------------------------------------------------------------------
D
N
K
R
L
L
I
L
G
A
------
G
R
G
Q
L
G
L
-
Y
K
A
A
K
E
L
----
G
----------------
I
H
T
-
I
A
G
T
M
P
-
N
A
H
-
K
P
C
-----
L
-------
N
L
A
D
E
I
S
Y
M
D
I
--
S
--
N
P
D
E
V
E
Q
K
V
K
D
L
N
L
D
G
A
A
T
C
C
L
D
T
G
I
V
S
L
A
-
R
I
C
D
K
--
E
N
L
V
G
L
N
-
E
E
A
A
------------
I
M
C
----
G
D
K
Y
K
M
K
E
A
F
K
K
Y
N
V
N
T
A
R
H
F
V
-
V
R
N
--
E
N
E
L
K
N
A
L
E
N
L
K
L
P
-----
V
I
V
K
A
T
--
D
L
I
Y
I
A
K
K
E
E
E
A
I
D
G
F
N
E
T
M
N
L
TKRD
Y
C
I
V
E
E
F
I
E
G
Y
E
F
G
A
Q
A
F
V
--
Y
K
N
D
V
L
F
V
M
P
--
H
G
D
E
--
T
Y
M
S
H
T
A
V
P
V
G
H
Y
V
P
L
D
-
V
K
D
D
I
I
E
K
T
K
T
E
V
K
K
A
I
K
A
L
GLNN
C
A
V
N
V
D
M
------
I
L
K
DN
E
V
Y
I
I
E
L
T
G
R
V
G
A
NC
L
P
E
L
V
E
I
N
Y
G
-
I
E
Y
Y
--
K
M
I
A
S
M
A
I
S
E
NP---
L
V
-
F
W
S
Q
KSK
E
N
K
A
G
L
A
R
M
I
I
E
T
E
K
S
G
I
--
L
-------------------
K
E
-
I
L
N
S
N
A
K
D
D
D
I
--------
V
E
I
T
F
F
KEEN
D
E
I
K
KFENSND
C
I
G
--
Q
I
I
V
K
E
-
E
T
L
D
K
C
K
D
K
L
D
V
I
I
N
N
I
N
I
I
L
K----------
17
Fugue
32.81
23%
-24
- C3 -
3TWE
2
?
A:
[1-26]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
N
A
D
E
L
Y
K
E
L
E
D
L
Q
E
R
L
R
K
L
R
K
K
L
R
S
-------------
7
HHSearch
28.93
11%
-320
- C3 -
2JO1
-
PLM_HUMAN
A:
[22-40]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
--------
I
A
G
I
L
F
---------------
I
L
G
--
I
L
I
V
L
S
R
R
C
------------------------------
8
HHSearch
26.72
35%
-212
- C3 -
2JP3
-
FXYD4_RAT
A:
[23-42]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
--------
F
G
G
L
L
C
---------------
I
A
G
--
I
A
L
A
L
S
G
K
C
K
-----------------------------
12
Fugue
26.32
36%
246
- C3 -
2GWW
-
B:
[9-30]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
N
I
Y
K
A
A
K
D
V
T
T
S
L
S
K
V
L
K
N
I
N
--------------
6
HHSearch
25.09
5%
-192
- C3 -
3JBR
-
CCG1_RABIT
E:
[185-206]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
C
--------
A
A
F
V
L
L
---------------
F
L
G
--
G
I
S
L
L
L
F
S
L
P
R
----------------------------
15
Fugue
24.82
20%
142
* C3 *
2IBF
-
IPAA_SHIFL
B:
[1-25]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
H
A
I
Y
E
K
A
K
E
V
S
S
A
L
S
K
V
L
S
K
I
D
D
T
------------
10
HHSearch
24.59
18%
-177
- C3 -
5AZB
4
LGT_ECOLI
A:
[261-287]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
S
M
G
Q
I
--------
L
S
I
P
M
I
---------------
V
A
G
--
V
I
M
M
V
W
A
Y
R
R
S
P
---------------------------
1
PsiBlast_PDB
24.30
46%
-264
- C3 -
4IU8
1
NARU_ECOLI
A:
[131-177]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
I
V
I
A
L
L
C
G
F
A
G
A
N
-----
F
A
S
S
M
G
--
N
I
S
F
F
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
Fugue
22.82
21%
169
- C3 -
2HSQ
-
B:
[1-23]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
I
Y
E
K
A
K
E
V
S
S
A
L
S
K
V
L
S
K
I
D
D
T
------------
19
Fugue
21.74
21%
206
* C2 *
1P5K
1
RL1_HELPY
A:
[1-19]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
K
V
F
K
R
L
E
K
S
F
S
K
I
Q
N
D
K
------------------
9
HHSearch
20.64
12%
-147
- C3 -
4HE8
1
NQO10_THET8
J:
[127-160]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
-------------------
G
P
L
L
Y
G
D
W
L
F
V
L
L
A
--------
V
G
F
L
L
M
AA-------------
T
V
V
--
A
V
A
L
V
E
P
G
-------------------------------
4
HHSearch
18.12
9%
-
- C3 -
3B5D
1
EMRE_ECOLI
A:
[31-105]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
-------
P
S
-----
V
G
T
I
I
C
Y
------
C
A
S
F
W
L
L
A
Q
T
-
L
-----
A
-
Y
I
P
-
T
G
I
A
-----
Y
A
I
W
S
------
G
V
G
I
V
L
I
-
S
-------
L
--
L
-------------------
S
W
G
F
F
G
Q
R
L
D
L
P
A
I
--------
I
G
M
M
L
I
---------------
C
A
G
--
V
L
I
I
N
L
L
S
-------------------------------
11
HHSearch
15.66
24%
94
- C3 -
2MKV
-
ATNG_HUMAN
A:
[30-50]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
--------
F
A
G
L
A
F
---------------
I
V
G
--
L
L
I
L
L
S
R
R
F
R
S
----------------------------
5
HHSearch
15.18
12%
-
- C3 -
3B5D
1
EMRE_ECOLI
A:
[30-105]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
W
P
S
V
G
T
I
I
C
Y
C
A
S
F
W
L
L
A
Q
T
L
A
Y
I
P
T
--
G
---
I
A
Y
A
I
W
S
G
------------
V
-
G
----
I
-------
V
L
I
S
L
L
S
W
G
F
F
G
Q
R
-
L
D
L
--
P
A
I
I
G
M
M
L
I
C
A
G
V
L
-----
I
I
N
L
L
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------