@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu27200: (2016-07-12 )
MAFRKPDEIAEAAIEAGMKKIKLPLPSLLVLGFLGGAFIALGYLLDIRVIGDLPKEWGSLSSLIGAAVFPVGLILVVLAGAELITGNMMSVAMALFSRKISVKELAINWGIVTIMNLIGALFVAYFFGHLVGLTETGPYLEKTIAVAQGKLDMSFGKVLISAIGCNWLVCLAVWLSFGAQDAAGKILGIWFPIMAFVAIGFQHVVANMFVIPAAIFAGSFTWGQFIGNIIPAFIGNVIGGAVFVGLIYFIAYHKKDRSRKEMKQVS
Atome Classification :
(21 SA)
.........10.......-.20......---..30........40........50--.---........-60........70........80........90........100.......110.......120........130....--.--...140........150.......160.......170.......180.......190.......200.......210...----..---.-------------------.-------------------220..----------------.--------------------..-..230.......240.......250.......260....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MAFR
K
P
D
E
I
A
E
A
A
I
E
A
G
M
-KKIKLP
L
P
S
---
L
L
V
L
G
F
L
G
G
A
F
I
A
L
G
Y
L
L
D
I
R
V
I---G---DL
P
K
E
W
G
S
-
L
S
S
L
I
G
A
A
V
F
P
V
G
L
I
L
V
V
LAG
A
E
LITG
N
M
M
S
V
A
M
A
L
F
SRKISV
K
E
L
A
IN
W
G
I
V
T
I
M
N
L
I
G
A
L
-
F
V
A
Y
F
F
G
H
L
-VGLTE--T--G
P
Y
L
E
-
K
T
I
A
V
AQGK
L
D
M
S
F
G
K
V
L
I
S
A
IG
C
N
W
L
V
C
L
A
V
W
L
SFGAQDAAGK
I
L
G
I
W
F
P
I
M
A
F
V
A
I
G
F
Q
H
V
V
A
N
M
F
V
I
P
A
A
I
----FA---G-------------------S-------------------
F
T
W
G
Q
----------------
F
--------------------
I
G
-
N
I
I
P
A
F
I
G
N
V
I
G
G
A
V
F
V
G
L
I
Y
F
I
A
YHKKDR
S
R
K
E
M
K
QVS
2
PsiBlast_PDB
82.69
32%
-186
- C6 -
3KLZ
13
?
A:
[21-278]
---------------
T
G
E
-
G
K
A
K
K
A
A
Y
K
---
S
F
L
L
A
I
S
A
G
I
Q
I
G
I
A
F
V
F
Y
T
V
V
T
---
T
GAH
D
M
P
Y
---
G
-
V
T
K
L
L
G
G
L
A
F
S
L
G
L
I
L
V
V
I
T
G
G
E
L
F
T
S
S
V
L
-
I
L
V
A
K
A
S
G
K
I
S
W
K
E
L
V
R
N
W
T
V
V
Y
F
G
N
L
C
G
S
I
-
I
L
V
F
I
M
L
A
T
-
R
Q
F
M
E
--
D
--
G
G
Q
L
G
L
N
A
M
A
I
S
Q
H
K
L
H
H
T
F
L
Q
A
F
A
L
G
L
M
C
N
I
L
V
C
L
A
V
W
M
T
F
S
A
R
S
L
T
D
K
V
M
V
L
I
L
P
V
A
M
F
V
S
S
G
F
E
H
C
I
A
N
M
F
Q
V
P
M
A
I
G
I
K
Y
F
A
---
P
-------------------
E
-------------------
S
F
W
A
M
T
GANIAQYADLN
F
V
N
F
I
--------------------
V
N
-
N
L
I
P
V
T
L
G
N
I
V
G
G
G
V
F
V
G
M
W
Y
W
L
I
Y
L
-------------
63
HHSearch
82.12
33%
-180
- C6 -
3KLY
4
?
A:
[22-278]
----------------
G
E
-
G
K
A
K
K
A
A
Y
K
---
S
F
L
L
A
I
S
A
G
I
Q
I
G
I
A
F
V
F
Y
T
V
V
T
---
T
---
G
A
H
D
M
P
Y
G
-
V
T
K
L
L
G
G
L
A
F
S
L
G
L
I
L
V
V
I
T
G
G
E
L
F
T
S
S
V
L
I
-
L
V
A
K
A
S
G
K
I
S
W
K
E
L
V
R
N
W
T
V
V
Y
F
G
N
L
C
G
S
I
-
I
L
V
F
I
M
L
-
A
-
T
R
Q
F
M
--
E
DG
G
Q
L
G
L
-
N
A
M
A
I
S
Q
H
K
L
H
H
T
F
L
Q
A
F
A
L
G
L
M
C
N
I
L
V
C
L
A
V
W
M
T
F
S
A
R
S
L
T
D
K
V
M
V
L
I
L
P
V
A
M
F
V
S
S
G
F
E
H
C
I
A
N
M
F
Q
V
P
M
A
I
----
G
I
---
K
Y
FAP
E
S
F
W
A
M
T
GANIAQYA
D
-------------------
L
N
F
V
N
F
---------------
I
--------------------
V
N
-
N
L
I
P
V
T
L
G
N
I
V
G
G
G
V
F
V
G
M
W
Y
W
L
I
Y
L
-------------
8
PsiBlast_PDB
81.54
32%
-140
- C6 -
3TE2
5
?
A:
[3-259]
---
R
A
H
K
E
T
L
D
K
L
T
N
A
A
I
-
N
S
I
N
L
L
N
T
S
K
V
K
Y
L
V
S
S
A
F
A
G
L
Y
V
G
I
G
I
L
L
-
I
F
T
I
---
G
---
G
L
L
T
D
A
G
S
P
M
T
K
I
V
M
G
L
S
F
A
I
A
L
S
L
V
I
M
T
G
T
E
L
F
T
G
N
N
M
V
M
S
A
G
M
L
N
K
G
V
S
I
K
D
T
S
K
I
W
A
Y
S
W
V
G
N
L
I
G
A
L
-
V
L
G
I
I
F
V
G
--
T
G
L
V
D
--
K
--
G
P
V
A
E
-
F
F
A
N
T
A
A
S
K
A
S
M
P
F
T
A
L
F
F
R
G
I
L
C
N
I
L
V
C
V
S
V
L
C
S
F
R
T
N
S
D
T
A
K
I
I
M
I
F
L
C
L
F
A
F
I
T
S
G
F
E
H
S
V
A
N
M
T
I
Y
S
V
S
L
----
F
S
PTI
S
-------------------
T
-------------------
V
T
I
G
G
----------------
A
--------------------
I
Y
-
N
L
V
A
V
T
L
G
N
I
V
G
G
A
L
F
M
G
L
G
T
Y
I
L
G
K
E
K
-----------
11
PsiBlast_PDB
81.21
32%
-157
- C6 -
3Q7K
1
?
A:
[13-274]
------
A
A
M
A
K
V
A
E
E
A
G
V
Y
K
A
T
K
H
P
L
K
T
---
F
Y
-
L
A
I
T
A
G
V
F
I
S
I
A
F
V
F
Y
I
T
A
T
TGT
G
---
A
M
P
Y
---
G
-
M
A
K
L
I
G
G
I
C
F
S
L
G
L
I
L
C
V
I
C
G
A
D
L
F
T
S
T
V
L
-
I
V
V
A
K
A
S
G
R
I
T
W
G
Q
L
A
K
N
W
L
N
V
Y
F
G
N
L
I
G
A
L
L
F
V
L
L
M
W
L
S
G
-
E
Y
M
T
A
--
N
--
G
Q
W
G
L
-
N
V
L
Q
T
A
D
H
K
M
H
H
T
F
I
E
A
V
C
L
G
I
L
A
N
L
M
V
C
L
A
V
W
M
S
Y
S
G
R
S
L
M
D
K
A
F
I
M
V
L
P
V
A
M
F
V
A
S
G
F
E
H
S
I
A
N
M
F
M
I
P
M
G
I
----
V
I
---
R
-------------------
D
-------------------
F
A
T
P
E
----------------
F
W
T
A
V
GSSPESFSHLT
V
M
S
F
I
T
D
-
N
L
I
P
V
T
I
G
N
I
I
G
G
G
L
L
V
G
L
T
Y
------------------
56
PsiBlast_CBE
81.06
32%
-153
- C6 -
3Q7K
3
?
H:
[12-275]
-----
P
A
A
M
A
K
V
A
E
E
A
G
V
Y
K
A
T
K
H
P
L
K
T
---
F
Y
-
L
A
I
T
A
G
V
F
I
S
I
A
F
V
F
Y
I
T
A
T
TGT
G
---
A
M
P
Y
---
G
-
M
A
K
L
I
G
G
I
C
F
S
L
G
L
I
L
C
V
I
C
G
A
D
L
F
T
S
T
V
L
-
I
V
V
A
K
A
S
G
R
I
T
W
G
Q
L
A
K
N
W
L
N
V
Y
F
G
N
L
I
G
A
L
L
F
V
L
L
M
W
L
S
G
-
E
Y
M
T
A
--
N
--
G
Q
W
G
L
-
N
V
L
Q
T
A
D
H
K
M
H
H
T
F
I
E
A
V
C
L
G
I
L
A
N
L
M
V
C
L
A
V
W
M
S
Y
S
G
R
S
L
M
D
K
A
F
I
M
V
L
P
V
A
M
F
V
A
S
G
F
E
H
S
I
A
N
M
F
M
I
P
M
G
I
----
V
I
---
R
-------------------
D
-------------------
F
A
T
P
E
----------------
F
WTAVG
S
S
P
E
S
F
SH
L
T
V
M
S
F
I
T
D
-
N
L
I
P
V
T
I
G
N
I
I
G
G
G
L
L
V
G
L
T
Y
W
-----------------
7
PsiBlast_PDB
81.05
32%
-138
- C6 -
3TE0
1
?
A:
[3-259]
---
R
A
H
K
E
T
L
D
K
L
T
N
A
A
I
-
N
K
I
N
L
L
N
T
S
K
V
K
Y
L
V
S
S
A
F
A
G
L
Y
V
G
I
G
I
L
L
-
I
F
T
I
---
G
---
G
L
L
T
D
A
G
S
P
M
T
K
I
V
M
G
L
S
F
A
I
A
L
S
L
V
I
M
T
G
T
E
L
F
T
G
N
N
M
V
M
S
A
G
M
L
N
K
G
V
S
I
K
D
T
S
K
I
W
A
Y
S
W
V
G
N
L
I
G
A
L
-
V
L
G
I
I
F
V
G
--
T
G
L
V
D
--
K
--
G
P
V
A
E
-
F
F
A
N
T
A
A
S
E
A
S
M
P
F
T
A
L
F
F
R
G
I
L
C
N
I
L
V
C
V
S
V
L
C
S
F
R
T
N
S
D
T
A
K
I
I
M
I
F
L
C
L
F
A
F
I
T
S
G
F
E
H
S
V
A
N
M
T
I
Y
S
V
S
L
----
F
S
PTI
S
-------------------
T
-------------------
V
T
I
G
G
----------------
A
--------------------
I
Y
-
N
L
V
A
V
T
L
G
N
I
V
G
G
A
L
F
M
G
L
G
T
Y
I
L
G
K
E
K
-----------
44
PsiBlast_CBE
80.97
32%
-138
- C6 -
3TE2
2
?
C:
[3-265]
---
R
A
H
K
E
T
L
D
K
L
T
N
A
A
I
-
N
S
I
N
L
L
N
T
S
KVK
Y
L
V
S
S
A
F
A
G
L
Y
V
G
I
G
I
L
L
-
I
F
T
I
---
G
---
G
L
L
T
D
A
G
S
P
M
T
K
I
V
M
G
L
S
F
A
I
A
L
S
L
V
I
M
T
G
T
E
L
F
T
G
N
N
M
V
M
S
A
G
M
L
N
K
G
V
S
I
K
D
T
S
K
I
W
A
Y
S
W
V
G
N
L
I
G
A
L
-
V
L
G
I
I
F
V
G
--
T
G
L
V
D
--
K
--
G
P
V
A
E
-
F
F
A
N
T
A
A
S
K
A
S
M
P
F
T
A
L
F
F
R
G
I
L
C
N
I
L
V
C
V
S
V
L
C
S
F
R
T
N
S
D
T
A
K
I
I
M
I
F
L
C
L
F
A
F
I
T
S
G
F
E
H
S
V
A
N
M
T
I
Y
S
V
S
L
----
F
S
PTI
S
-------------------
T
-------------------
V
T
I
G
G
----------------
A
--------------------
I
Y
-
N
L
V
A
V
T
L
G
N
I
V
G
G
A
L
F
M
G
L
G
T
Y
I
L
G
K
E
K
L
N
A
A
A
E
-----
79
Fugue
80.93
32%
-200
* C6 *
3KCU
1
FOCA_ECO57
A:
[29-280]
-----------------------
K
H
P
L
K
---
T
F
Y
L
A
I
T
A
G
V
F
I
S
I
A
F
V
F
Y
I
T
A
T
---
T
---
G
T
G
T
M
P
F
G
-
M
A
K
L
V
G
G
I
C
F
S
L
G
L
I
L
C
V
V
C
G
A
D
L
F
T
S
T
V
L
-
I
V
V
A
K
A
S
G
R
I
T
W
G
Q
L
A
K
N
W
L
N
V
Y
F
G
N
L
V
G
A
L
-
L
F
V
L
L
M
W
L
S
G
E
Y
M
T
A
--
N
--
G
Q
W
G
L
-
N
V
L
Q
T
A
D
H
K
V
H
H
T
F
I
E
A
V
C
L
G
I
L
A
N
L
M
V
C
L
A
V
W
M
S
Y
S
G
R
S
L
M
D
K
A
F
I
M
V
L
P
V
A
M
F
V
A
S
G
F
E
H
S
I
A
N
M
F
M
I
P
M
G
I
----
V
I
---
R
-------------------
D
F
AS
P
E
F
W
T
A
V
GSAPENFSH
L
T
V
M
N
----------------
F
--------------------
I
T
D
N
L
I
P
V
T
I
G
N
I
I
G
G
G
L
L
V
G
L
T
Y
W
V
I
Y
L
R
------------
9
PsiBlast_PDB
80.91
32%
-140
- C6 -
3TE1
3
?
A:
[3-259]
---
R
A
H
K
E
T
L
D
K
L
T
N
A
A
I
-
N
K
I
N
L
L
N
T
S
K
V
K
Y
L
V
S
S
A
F
A
G
L
Y
V
G
I
G
I
L
L
-
I
F
T
I
---
G
---
G
L
L
T
D
A
G
S
P
M
T
K
I
V
M
G
L
S
F
A
I
A
L
S
L
V
I
M
T
G
T
E
L
F
A
G
N
N
M
V
M
S
A
G
M
L
N
K
G
V
S
I
K
D
T
S
K
I
W
A
Y
S
W
V
G
N
L
I
G
A
L
-
V
L
G
I
I
F
V
G
--
T
G
L
V
D
--
K
--
G
P
V
A
E
-
F
F
A
N
T
A
A
S
K
A
S
M
P
F
T
A
L
F
F
R
G
I
L
C
N
I
L
V
C
V
S
V
L
C
S
F
R
T
N
S
D
T
A
K
I
I
M
I
F
L
C
L
F
A
F
I
T
S
G
F
E
H
S
V
A
N
M
T
I
Y
S
V
S
L
----
F
S
PTI
S
-------------------
T
-------------------
V
T
I
G
G
----------------
A
--------------------
I
Y
-
N
L
V
A
V
T
L
G
N
I
V
G
G
A
L
F
M
G
L
G
T
Y
I
L
G
K
E
K
-----------
48
PsiBlast_CBE
80.90
32%
-134
- C6 -
3TE1
2
?
C:
[3-265]
---
R
A
H
K
E
T
L
D
K
L
T
N
A
A
I
-
N
K
I
N
L
L
N
T
S
KVK
Y
L
V
S
S
A
F
A
G
L
Y
V
G
I
G
I
L
L
-
I
F
T
I
---
G
---
G
L
L
T
D
A
G
S
P
M
T
K
I
V
M
G
L
S
F
A
I
A
L
S
L
V
I
M
T
G
T
E
L
F
A
G
N
N
M
V
M
S
A
G
M
L
N
K
G
V
S
I
K
D
T
S
K
I
W
A
Y
S
W
V
G
N
L
I
G
A
L
-
V
L
G
I
I
F
V
G
--
T
G
L
V
D
--
K
--
G
P
V
A
E
-
F
F
A
N
T
A
A
S
K
A
S
M
P
F
T
A
L
F
F
R
G
I
L
C
N
I
L
V
C
V
S
V
L
C
S
F
R
T
N
S
D
T
A
K
I
I
M
I
F
L
C
L
F
A
F
I
T
S
G
F
E
H
S
V
A
N
M
T
I
Y
S
V
S
L
----
F
S
PTI
S
-------------------
T
-------------------
V
T
I
G
G
----------------
A
--------------------
I
Y
-
N
L
V
A
V
T
L
G
N
I
V
G
G
A
L
F
M
G
L
G
T
Y
I
L
G
K
E
K
L
N
A
A
A
E
-----
41
PsiBlast_CBE
80.83
32%
-140
- C6 -
3TE0
1
?
B:
[3-259]
---
R
A
H
K
E
T
L
D
K
L
T
N
A
A
I
-
N
K
I
N
L
L
N
T
S
KVK
Y
L
V
S
S
A
F
A
G
L
Y
V
G
I
G
I
L
L
-
I
F
T
I
---
G
---
G
L
L
T
D
A
G
S
P
M
T
K
I
V
M
G
L
S
F
A
I
A
L
S
L
V
I
M
T
G
T
E
L
F
T
G
N
N
M
V
M
S
A
G
M
L
N
K
G
V
S
I
K
D
T
S
K
I
W
A
Y
S
W
V
G
N
L
I
G
A
L
-
V
L
G
I
I
F
V
G
--
T
G
L
V
D
--
K
--
G
P
V
A
E
-
F
F
A
N
T
A
A
S
E
A
S
M
P
F
T
A
L
F
F
R
G
I
L
C
N
I
L
V
C
V
S
V
L
C
S
F
R
T
N
S
D
T
A
K
I
I
M
I
F
L
C
L
F
A
F
I
T
S
G
F
E
H
S
V
A
N
M
T
I
Y
S
V
S
L
----
F
S
PTI
S
-------------------
T
-------------------
V
T
I
G
G
----------------
A
--------------------
I
Y
-
N
L
V
A
V
T
L
G
N
I
V
G
G
A
L
F
M
G
L
G
T
Y
I
L
G
K
E
K
-----------
45
PsiBlast_CBE
80.77
32%
-142
- C6 -
3TE2
4
?
B:
[3-259]
---
R
A
H
K
E
T
L
D
K
L
T
N
A
A
I
-
N
S
I
N
L
L
N
T
S
KVK
Y
L
V
S
S
A
F
A
G
L
Y
V
G
I
G
I
L
L
-
I
F
T
I
---
G
---
G
L
L
T
D
A
G
S
P
M
T
K
I
V
M
G
L
S
F
A
I
A
L
S
L
V
I
M
T
G
T
E
L
F
T
G
N
N
M
V
M
S
A
G
M
L
N
K
G
V
S
I
K
D
T
S
K
I
W
A
Y
S
W
V
G
N
L
I
G
A
L
-
V
L
G
I
I
F
V
G
--
T
G
L
V
D
--
K
--
G
P
V
A
E
-
F
F
A
N
T
A
A
S
K
A
S
M
P
F
T
A
L
F
F
R
G
I
L
C
N
I
L
V
C
V
S
V
L
C
S
F
R
T
N
S
D
T
A
K
I
I
M
I
F
L
C
L
F
A
F
I
T
S
G
F
E
H
S
V
A
N
M
T
I
Y
S
V
S
L
----
F
S
PTI
S
-------------------
T
-------------------
V
T
I
G
G
----------------
A
--------------------
I
Y
-
N
L
V
A
V
T
L
G
N
I
V
G
G
A
L
F
M
G
L
G
T
Y
I
L
G
K
E
K
-----------
1
PsiBlast_PDB
80.68
32%
-183
- C6 -
3KLY
4
?
A:
[22-278]
----------------
G
E
-
G
K
A
K
K
A
A
Y
K
---
S
F
L
L
A
I
S
A
G
I
Q
I
G
I
A
F
V
F
Y
T
V
V
T
---
T
GAH
D
M
P
Y
---
G
-
V
T
K
L
L
G
G
L
A
F
S
L
G
L
I
L
V
V
I
T
G
G
E
L
F
T
S
S
V
L
-
I
L
V
A
K
A
S
G
K
I
S
W
K
E
L
V
R
N
W
T
V
V
Y
F
G
N
L
C
G
S
I
-
I
L
V
F
I
M
L
A
T
-
R
Q
F
M
E
--
D
--
G
G
Q
L
G
L
N
A
M
A
I
S
Q
H
K
L
H
H
T
F
L
Q
A
F
A
L
G
L
M
C
N
I
L
V
C
L
A
V
W
M
T
F
S
A
R
S
L
T
D
K
V
M
V
L
I
L
P
V
A
M
F
V
S
S
G
F
E
H
C
I
A
N
M
F
Q
V
P
M
A
I
G
I
K
Y
F
A
---
P
-------------------
E
-------------------
S
F
W
A
M
T
GANIAQYADLN
F
V
N
F
I
--------------------
V
N
-
N
L
I
P
V
T
L
G
N
I
V
G
G
G
V
F
V
G
M
W
Y
W
L
I
Y
L
-------------
47
PsiBlast_CBE
80.67
32%
-142
- C6 -
3TE1
2
?
D:
[3-259]
---
R
A
H
K
E
T
L
D
K
L
T
N
A
A
I
-
N
K
I
N
L
L
N
T
S
KVK
Y
L
V
S
S
A
F
A
G
L
Y
V
G
I
G
I
L
L
-
I
F
T
I
---
G
---
G
L
L
T
D
A
G
S
P
M
T
K
I
V
M
G
L
S
F
A
I
A
L
S
L
V
I
M
T
G
T
E
L
F
A
G
N
N
M
V
M
S
A
G
M
L
N
K
G
V
S
I
K
D
T
S
K
I
W
A
Y
S
W
V
G
N
L
I
G
A
L
-
V
L
G
I
I
F
V
G
--
T
G
L
V
D
--
K
--
G
P
V
A
E
-
F
F
A
N
T
A
A
S
K
A
S
M
P
F
T
A
L
F
F
R
G
I
L
C
N
I
L
V
C
V
S
V
L
C
S
F
R
T
N
S
D
T
A
K
I
I
M
I
F
L
C
L
F
A
F
I
T
S
G
F
E
H
S
V
A
N
M
T
I
Y
S
V
S
L
----
F
S
PTI
S
-------------------
T
-------------------
V
T
I
G
G
----------------
A
--------------------
I
Y
-
N
L
V
A
V
T
L
G
N
I
V
G
G
A
L
F
M
G
L
G
T
Y
I
L
G
K
E
K
-----------
29
PsiBlast_CBE
80.54
32%
-135
- C6 -
3TDO
3
?
C:
[3-265]
---
R
A
H
K
E
T
L
D
K
L
T
N
A
A
I
-
N
K
I
N
L
L
N
T
S
KVK
Y
L
V
S
S
A
F
A
G
L
Y
V
G
I
G
I
L
L
-
I
F
T
I
---
G
---
G
L
L
T
D
A
G
S
P
M
T
K
I
V
M
G
L
S
F
A
I
A
L
S
L
V
I
M
T
G
T
E
L
F
T
G
N
N
M
V
M
S
A
G
M
L
N
K
G
V
S
I
K
D
T
S
K
I
W
A
Y
S
W
V
G
N
L
I
G
A
L
-
V
L
G
I
I
F
V
G
--
T
G
L
V
D
--
K
--
G
P
V
A
E
-
F
F
A
N
T
A
A
S
K
A
S
M
P
F
T
A
L
F
F
R
G
I
L
C
N
I
L
V
C
V
S
V
L
C
S
F
R
T
N
S
D
T
A
K
I
I
M
I
F
L
C
L
F
A
F
I
T
S
G
F
E
H
S
V
A
N
M
T
I
Y
S
V
S
L
----
F
S
PTI
S
-------------------
T
-------------------
V
T
I
G
G
----------------
A
--------------------
I
Y
-
N
L
V
A
V
T
L
G
N
I
V
G
G
A
L
F
M
G
L
G
T
Y
I
L
G
K
E
K
L
N
A
A
A
E
-----
43
PsiBlast_CBE
80.46
32%
-140
- C6 -
3TE2
3
?
D:
[3-259]
---
R
A
H
K
E
T
L
D
K
L
T
N
A
A
I
-
N
S
I
N
L
L
N
T
S
KVK
Y
L
V
S
S
A
F
A
G
L
Y
V
G
I
G
I
L
L
-
I
F
T
I
---
G
---
G
L
L
T
D
A
G
S
P
M
T
K
I
V
M
G
L
S
F
A
I
A
L
S
L
V
I
M
T
G
T
E
L
F
T
G
N
N
M
V
M
S
A
G
M
L
N
K
G
V
S
I
K
D
T
S
K
I
W
A
Y
S
W
V
G
N
L
I
G
A
L
-
V
L
G
I
I
F
V
G
--
T
G
L
V
D
--
K
--
G
P
V
A
E
-
F
F
A
N
T
A
A
S
K
A
S
M
P
F
T
A
L
F
F
R
G
I
L
C
N
I
L
V
C
V
S
V
L
C
S
F
R
T
N
S
D
T
A
K
I
I
M
I
F
L
C
L
F
A
F
I
T
S
G
F
E
H
S
V
A
N
M
T
I
Y
S
V
S
L
----
F
S
PTI
S
-------------------
T
-------------------
V
T
I
G
G
----------------
A
--------------------
I
Y
-
N
L
V
A
V
T
L
G
N
I
V
G
G
A
L
F
M
G
L
G
T
Y
I
L
G
K
E
K
-----------
54
PsiBlast_CBE
80.34
32%
-167
- C6 -
3Q7K
1
?
J:
[12-279]
-----
P
A
A
M
A
K
V
A
E
E
A
G
V
Y
K
A
T
K
H
P
L
K
T
---
F
Y
-
L
A
I
T
A
G
V
F
I
S
I
A
F
V
F
Y
I
T
A
T
TGT
G
---
A
M
P
Y
---
G
-
M
A
K
L
I
G
G
I
C
F
S
L
G
L
I
L
C
V
I
C
G
A
D
L
F
T
S
T
V
L
-
I
V
V
A
K
A
S
G
R
I
T
W
G
Q
L
A
K
N
W
L
N
V
Y
F
G
N
L
I
G
A
L
L
F
V
L
L
M
W
L
S
G
-
E
Y
M
T
A
--
N
--
G
Q
W
G
L
-
N
V
L
Q
T
A
D
H
K
M
H
H
T
F
I
E
A
V
C
L
G
I
L
A
N
L
M
V
C
L
A
V
W
M
S
Y
S
G
R
S
L
M
D
K
A
F
I
M
V
L
P
V
A
M
F
V
A
S
G
F
E
H
S
I
A
N
M
F
M
I
P
M
G
I
----
V
I
---
R
-------------------
D
-------------------
F
A
T
P
E
----------------
F
WTAVGSSPESFSHLTVMSFI
T
D
-
N
L
I
P
V
T
I
G
N
I
I
G
G
G
L
L
V
G
L
T
Y
W
V
I
Y
L
-------------
64
HHSearch
80.27
32%
-181
- C6 -
3KCU
1
FOCA_ECO57
A:
[29-280]
-----------------------
K
H
P
L
K
---
T
F
Y
L
A
I
T
A
G
V
F
I
S
I
A
F
V
F
Y
I
T
A
T
---
T
---
G
T
G
T
M
P
F
G
-
M
A
K
L
V
G
G
I
C
F
S
L
G
L
I
L
C
V
V
C
G
A
D
L
F
T
S
T
V
L
I
-
V
V
A
K
A
S
G
R
I
T
W
G
Q
L
A
K
N
W
L
N
V
Y
F
G
N
L
V
G
A
L
-
L
F
V
L
L
M
W
-
L
-
S
G
E
Y
M
TA
N
--
G
Q
W
G
L
-
N
V
L
Q
T
A
D
H
K
V
H
H
T
F
I
E
A
V
C
L
G
I
L
A
N
L
M
V
C
L
A
V
W
M
S
Y
S
G
R
S
L
M
D
K
A
F
I
M
V
L
P
V
A
M
F
V
A
S
G
F
E
H
S
I
A
N
M
F
M
I
P
M
G
I
----
V
I
---
R
D
F
AS
P
E
F
W
T
A
V
GSAPENFS
H
-------------------
L
T
V
M
N
F
---------------
I
--------------------
T
D
-
N
L
I
P
V
T
I
G
N
I
I
G
G
G
L
L
V
G
L
T
Y
W
V
I
Y
L
R
------------
30
PsiBlast_CBE
80.23
32%
-139
- C6 -
3TDO
3
?
B:
[3-259]
---
R
A
H
K
E
T
L
D
K
L
T
N
A
A
I
-
N
K
I
N
L
L
N
T
S
KVK
Y
L
V
S
S
A
F
A
G
L
Y
V
G
I
G
I
L
L
-
I
F
T
I
---
G
---
G
L
L
T
D
A
G
S
P
M
T
K
I
V
M
G
L
S
F
A
I
A
L
S
L
V
I
M
T
G
T
E
L
F
T
G
N
N
M
V
M
S
A
G
M
L
N
K
G
V
S
I
K
D
T
S
K
I
W
A
Y
S
W
V
G
N
L
I
G
A
L
-
V
L
G
I
I
F
V
G
--
T
G
L
V
D
--
K
--
G
P
V
A
E
-
F
F
A
N
T
A
A
S
K
A
S
M
P
F
T
A
L
F
F
R
G
I
L
C
N
I
L
V
C
V
S
V
L
C
S
F
R
T
N
S
D
T
A
K
I
I
M
I
F
L
C
L
F
A
F
I
T
S
G
F
E
H
S
V
A
N
M
T
I
Y
S
V
S
L
----
F
S
PTI
S
-------------------
T
-------------------
V
T
I
G
G
----------------
A
--------------------
I
Y
-
N
L
V
A
V
T
L
G
N
I
V
G
G
A
L
F
M
G
L
G
T
Y
I
L
G
K
E
K
-----------
37
PsiBlast_CBE
80.12
32%
-133
- C6 -
3TDX
3
?
C:
[3-265]
---
R
A
H
K
E
T
L
D
K
L
T
N
A
A
I
-
N
K
I
N
L
L
N
T
S
KVK
Y
L
V
S
S
A
F
A
G
L
Y
V
G
I
G
I
L
L
-
I
F
T
I
---
G
---
G
L
L
T
D
A
G
S
P
M
T
K
I
V
M
G
L
S
F
A
I
A
L
S
L
V
I
M
T
G
T
E
V
F
T
G
N
N
M
V
M
S
A
G
M
L
N
K
G
V
S
I
K
D
T
S
K
I
W
A
Y
S
W
V
G
N
L
I
G
A
L
-
V
L
G
I
I
F
V
G
--
T
G
L
V
D
--
K
--
G
P
V
A
E
-
F
F
A
N
T
A
A
S
K
A
S
M
P
F
T
A
L
F
F
R
G
I
L
C
N
I
L
V
C
V
S
V
L
C
S
F
R
T
N
S
D
T
A
K
I
I
M
I
F
L
C
L
F
A
F
I
T
S
G
F
E
H
S
V
A
N
M
T
I
Y
S
V
S
L
----
F
S
PTI
S
-------------------
T
-------------------
V
T
I
G
G
----------------
A
--------------------
I
Y
-
N
L
V
A
V
T
L
G
N
I
V
G
G
A
L
F
M
G
L
G
T
Y
I
L
G
K
E
K
L
N
A
A
A
E
-----
25
PsiBlast_CBE
76.79
32%
-190
- C6 -
3KLY
7
?
B:
[24-278]
-------------------
G
K
A
K
K
A
A
Y
K
---
S
F
L
L
A
I
S
A
G
I
Q
I
G
I
A
F
V
F
Y
T
V
V
T
---
T
GAH
D
M
P
Y
---
G
-
V
T
K
L
L
G
G
L
A
F
S
L
G
L
I
L
V
V
I
T
G
G
E
L
F
T
S
S
V
L
-
I
L
V
A
K
A
S
G
K
I
S
W
K
E
L
V
R
N
W
T
V
V
Y
F
G
N
L
C
G
S
I
-
I
L
V
F
I
M
L
A
T
-
R
Q
F
M
E
--
D
--
G
G
Q
L
G
L
N
A
M
A
I
S
Q
H
K
L
H
H
T
F
L
Q
A
F
A
L
G
L
M
C
N
I
L
V
C
L
A
V
W
M
T
F
S
A
R
S
L
T
D
K
V
M
V
L
I
L
P
V
A
M
F
V
S
S
G
F
E
H
C
I
A
N
M
F
Q
V
P
M
A
I
G
I
K
Y
F
A
---
P
-------------------
E
-------------------
S
F
W
A
M
T
GANIAQYADLN
F
V
N
F
I
--------------------
V
N
-
N
L
I
P
V
T
L
G
N
I
V
G
G
G
V
F
V
G
M
W
Y
W
L
I
Y
L
-------------