@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu27490: (2016-07-13 )
MQEGDYEKAAEAFTKAIEENKEDAIPYINFANLLSSVNELERALAFYDKALELDSSAATAYYGAGNVYVVKEMYKEAKDMFEKALRAGMENGDLFYMLGTVLVKLEQPKLALPYLQRAVELNENDTEARFQFGMCLANEGMLDEALSQFAAVTEQDPGHADAFYNAGVTYAYKENREKALEMLDKAIDIQPDHMLALHAKKLIDPS
Atome Classification :
(20 SA)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10........20....---....30....-....40........50........60........70........80........90...------.....100.......110.......120-------.......130.......140.......150....---...160.......170.......180......--.190.......200....--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQEG
D
Y
E
K
A
A
E
A
F
T
K
A
I
EENKEDAI---P
Y
I
N
F
A
N
L
L
S
-
S
V
N
E
L
E
R
A
L
A
F
Y
D
K
A
LELDSSA
A
T
A
Y
YGAG
N
V
Y
V
V
K
E
M
Y
K
E
A
K
D
M
F
E
K
A
L
R
AGMENGDL------
F
Y
M
L
G
T
V
L
VKLEQPK
L
A
L
P
Y
L
Q
R
A
V
ELN-------END
T
E
A
R
F
Q
F
G
M
C
LANE
G
M
L
D
E
A
L
S
Q
F
A
A
V
TEQD---PGH
A
D
A
FYNA
G
V
T
Y
A
YKE
N
R
E
K
A
L
E
M
L
D
K
AID--IQPD
H
M
L
A
L
H
A
K
K
LIDPS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
87.69
99%
-94
- C3 -
2Q7F
-
YRRB_BACSU
A:
[43-236]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
E
A
F
T
K
A
I
E
E
N
K
E
D
A
I
---
P
Y
I
N
F
A
N
L
L
S
-
S
V
N
E
L
E
R
A
L
A
F
Y
D
K
A
L
E
L
D
S
S
A
A
T
A
Y
Y
G
A
G
N
V
Y
V
V
K
E
M
Y
K
E
A
K
D
M
F
E
K
A
L
R
A
G
M
E
N
G
D
L
------
F
Y
M
L
G
T
V
L
V
K
L
E
Q
P
K
L
A
L
P
Y
L
Q
R
A
V
E
L
N
-------
E
N
D
T
E
A
R
F
Q
F
G
M
C
L
A
N
E
G
M
L
D
E
A
L
S
Q
F
A
A
V
T
E
Q
D
---
P
G
H
A
D
A
F
Y
N
A
G
V
T
Y
A
Y
K
E
N
R
E
K
A
L
E
M
L
D
K
A
I
D
--
I
Q
P
D
H
M
L
A
L
H
A
K
K
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
62
HHSearch
87.48
99%
-97
* C3 *
2Q7F
-
YRRB_BACSU
A:
[43-233]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
E
A
F
T
K
A
I
E
E
N
K
E
D
A
I
---
P
Y
I
N
F
A
N
L
L
S
-
S
V
N
E
L
E
R
A
L
A
F
Y
D
K
A
L
E
L
D
S
S
A
A
T
A
Y
Y
G
A
G
N
V
Y
V
V
K
E
M
Y
K
E
A
K
D
M
F
E
K
A
L
R
A
G
M
E
N
G
D
L
------
F
Y
M
L
G
T
V
L
V
K
L
E
Q
P
K
L
A
L
P
Y
L
Q
R
A
V
E
L
N
-------
E
N
D
T
E
A
R
F
Q
F
G
M
C
L
A
N
E
G
M
L
D
E
A
L
S
Q
F
A
A
V
T
E
Q
D
---
P
G
H
A
D
A
F
Y
N
A
G
V
T
Y
A
Y
K
E
N
R
E
K
A
L
E
M
L
D
K
A
I
D
--
I
Q
P
D
H
M
L
A
L
H
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
70.43
26%
-106
- C3 -
1W3B
-
OGT1_HUMAN
A:
[115-304]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
M
E
G
A
V
Q
A
Y
V
S
A
L
Q
Y
N
P
D
L
Y
C
---
V
R
S
D
L
G
N
L
L
K
-
A
L
G
R
L
E
E
A
K
A
C
Y
L
K
A
I
E
T
Q
P
N
F
A
V
A
W
S
N
L
G
C
V
F
N
A
Q
G
E
I
W
L
A
I
H
H
F
E
K
A
V
T
L
D
P
N
F
L
D
A
------
Y
I
N
L
G
N
V
L
K
E
A
R
I
F
D
R
A
V
A
A
Y
L
R
A
L
S
L
S
-------
P
N
H
A
V
V
H
G
N
L
A
C
V
Y
Y
E
Q
G
L
I
D
L
A
I
D
T
Y
R
R
A
I
E
L
Q
---
P
H
F
P
D
A
Y
C
N
L
A
N
A
L
K
E
K
G
S
V
A
E
A
E
D
C
Y
N
T
A
L
R
--
L
C
P
T
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
65.92
22%
-112
- C3 -
4UI9
-
CDC27_HUMAN
F:
[582-768]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
H
D
I
A
I
K
F
F
Q
R
A
I
Q
V
D
P
N
Y
A
Y
---
A
Y
T
L
L
G
H
E
F
V
-
L
T
E
E
L
D
K
A
L
A
C
F
R
N
A
I
R
V
N
P
R
H
Y
N
A
W
Y
G
L
G
M
I
Y
Y
K
Q
E
K
F
S
L
A
E
M
H
F
Q
K
A
L
D
I
N
P
Q
S
S
V
L
------
L
C
H
I
G
V
V
Q
H
A
L
K
K
S
E
K
A
L
D
T
L
N
K
A
I
V
I
D
-------
P
K
N
P
L
C
K
F
H
R
A
S
V
L
F
A
N
E
K
Y
K
S
A
L
Q
E
L
E
E
L
K
Q
I
V
---
P
K
E
S
L
V
Y
F
L
I
G
K
V
Y
K
K
L
G
Q
T
H
L
A
L
M
N
F
S
W
A
M
D
--
L
D
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
64.87
22%
-112
- C3 -
5A31
-
CDC27_HUMAN
F:
[582-768]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
H
D
I
A
I
K
F
F
Q
R
A
I
Q
V
D
P
N
Y
A
Y
---
A
Y
T
L
L
G
H
E
F
V
-
L
T
E
E
L
D
K
A
L
A
C
F
R
N
A
I
R
V
N
P
R
H
Y
N
A
W
Y
G
L
G
M
I
Y
Y
K
Q
E
K
F
S
L
A
E
M
H
F
Q
K
A
L
D
I
N
P
Q
S
S
V
L
------
L
C
H
I
G
V
V
Q
H
A
L
K
K
S
E
K
A
L
D
T
L
N
K
A
I
V
I
D
-------
P
K
N
P
L
C
K
F
H
R
A
S
V
L
F
A
N
E
K
Y
K
S
A
L
Q
E
L
E
E
L
K
Q
I
V
---
P
K
E
S
L
V
Y
F
L
I
G
K
V
Y
K
K
L
G
Q
T
H
L
A
L
M
N
F
S
W
A
M
D
--
L
D
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
71
HHSearch
64.20
17%
-100
- C3 -
4UI9
-
CDC23_HUMAN
C:
[338-548]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
S
Q
H
E
K
A
A
L
Y
F
Q
R
A
L
K
L
N
P
R
Y
L
G
---
A
W
T
L
M
G
H
E
Y
M
-
E
M
K
N
T
S
A
A
I
Q
A
Y
R
H
A
I
E
V
N
K
R
D
Y
R
A
W
Y
G
L
G
Q
T
Y
E
I
L
K
M
P
F
Y
C
L
Y
Y
Y
R
R
A
H
Q
L
R
P
N
D
S
R
M
------
L
V
A
L
G
E
C
Y
E
K
L
N
Q
L
V
E
A
K
K
C
Y
W
R
A
Y
A
V
G
-------
D
V
E
K
M
A
L
V
K
L
A
K
L
H
E
Q
L
T
E
S
E
Q
A
A
Q
C
Y
I
K
Y
I
Q
D
I
Y
S
C--
E
S
T
A
F
R
Y
L
A
Q
Y
Y
F
K
C
K
L
W
D
E
A
S
T
C
A
Q
K
C
C
A
--
F
N
D
T
R
E
E
G
K
A
L
L
R
Q
I
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
69
HHSearch
58.47
21%
-104
- C3 -
4UI9
-
CDC27_HUMAN
F:
[579-780]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
R
E
H
D
I
A
I
K
F
F
Q
R
A
I
Q
V
D
P
N
Y
A
Y
---
A
Y
T
L
L
G
H
E
F
V
-
L
T
E
E
L
D
K
A
L
A
C
F
R
N
A
I
R
V
N
P
R
H
Y
N
A
W
Y
G
L
G
M
I
Y
Y
K
Q
E
K
F
S
L
A
E
M
H
F
Q
K
A
L
D
I
N
P
Q
S
S
V
L
------
L
C
H
I
G
V
V
Q
H
A
L
K
K
S
E
K
A
L
D
T
L
N
K
A
I
V
I
D
-------
P
K
N
P
L
C
K
F
H
R
A
S
V
L
F
A
N
E
K
Y
K
S
A
L
Q
E
L
E
E
L
K
Q
I
V
---
P
K
E
S
L
V
Y
F
L
I
G
K
V
Y
K
K
L
G
Q
T
H
L
A
L
M
N
F
S
W
A
M
D
--
L
D
P
K
G
A
N
N
Q
I
K
E
A
I
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
57.06
21%
-67
- C3 -
3VTX
1
?
A:
[4-162]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
T
T
---
I
Y
M
D
I
G
D
K
K
R
-
T
K
G
D
F
D
G
A
I
R
A
Y
K
K
V
L
K
A
D
P
N
N
V
E
T
L
L
K
L
G
K
T
Y
M
D
I
G
L
P
N
D
A
I
E
S
L
K
K
F
V
V
L
D
T
T
S
A
E
A
------
Y
Y
I
L
G
S
A
N
F
M
I
D
E
K
Q
A
A
I
D
A
L
Q
R
A
I
A
L
N
-------
T
V
Y
A
D
A
Y
Y
K
L
G
L
V
Y
D
S
M
G
E
H
D
K
A
I
E
A
Y
E
K
T
I
S
I
K
---
P
G
F
I
R
A
Y
Q
S
I
G
L
A
Y
E
G
K
G
L
R
D
E
A
V
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
74
HHSearch
57.01
23%
-90
- C3 -
1W3B
-
OGT1_HUMAN
A:
[11-211]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
A
G
D
F
E
A
A
E
R
H
C
M
Q
L
W
R
Q
E
P
D
N
T
G
---
V
L
L
L
L
S
S
I
H
F
-
Q
C
R
R
L
D
R
S
A
H
F
S
T
L
A
I
K
Q
N
P
L
L
A
E
A
Y
S
N
L
G
N
V
Y
K
E
R
G
Q
L
Q
E
A
I
E
H
Y
R
H
A
L
R
L
K
P
D
F
I
D
G
------
Y
I
N
L
A
A
A
L
V
A
A
G
D
M
E
G
A
V
Q
A
Y
V
S
A
L
Q
Y
N
-------
P
D
L
Y
C
V
R
S
D
L
G
N
L
L
K
A
L
G
R
L
E
E
A
K
A
C
Y
L
K
A
I
E
T
Q
---
P
N
F
A
V
A
W
S
N
L
G
C
V
F
N
A
Q
G
E
I
W
L
A
I
H
H
F
E
K
A
V
T
--
L
D
P
N
F
L
D
A
Y
I
N
L
G
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
54.98
21%
-65
- C3 -
3VTY
1
?
A:
[3-162]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
T
T
---
I
Y
M
D
I
G
D
K
K
R
-
T
K
G
D
F
D
G
A
I
R
A
Y
K
K
V
L
K
A
D
P
N
N
V
E
T
L
L
K
L
G
K
T
Y
M
D
I
G
L
P
N
D
A
I
E
S
L
K
K
F
V
V
L
D
T
T
S
A
E
A
------
Y
Y
I
L
G
S
A
N
F
M
I
D
E
K
Q
A
A
I
D
A
L
Q
R
A
I
A
L
N
-------
T
V
Y
A
D
A
Y
Y
K
L
G
L
V
Y
D
S
M
G
E
H
D
K
A
I
E
A
Y
E
K
T
I
S
I
K
---
P
G
F
I
R
A
Y
Q
S
I
G
L
A
Y
E
G
K
G
L
R
D
E
A
V
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
54.60
33%
-77
- C3 -
1NA0
2
?
A:
[12-125]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
Y
N
L
G
N
A
Y
Y
-
K
Q
G
D
Y
D
E
A
I
E
Y
Y
Q
K
A
L
E
L
D
P
N
N
A
E
A
W
Y
N
L
G
N
A
Y
Y
K
Q
G
D
Y
D
E
A
I
E
Y
Y
Q
K
A
L
E
L
D
P
N
N
A
E
A
------
W
Y
N
L
G
N
A
Y
Y
K
Q
G
D
Y
D
E
A
I
E
Y
Y
Q
K
A
L
E
L
D
-------
P
N
N
A
E
A
K
Q
N
L
G
N
A
K
Q
K
Q
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
54.59
26%
-96
- C3 -
3AS5
1
?
A:
[49-170]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
I
A
Y
V
K
T
G
A
V
D
R
G
T
E
L
L
E
R
S
L
A
D
A
P
D
N
V
K
V
------
A
T
V
L
G
L
T
Y
V
Q
V
Q
K
Y
D
L
A
V
P
L
L
I
K
V
A
E
A
N
-------
P
I
N
F
N
V
R
F
R
L
G
V
A
L
D
N
L
G
R
F
D
E
A
I
D
S
F
K
I
A
L
G
L
R
---
P
N
E
G
K
V
H
R
A
I
A
F
S
Y
E
Q
M
G
R
H
E
E
A
L
P
H
F
K
K
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
73
HHSearch
54.38
17%
-85
- C3 -
2XPI
1
CUT9_SCHPO
A:
[387-594]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
K
I
S
E
A
R
R
Y
F
S
K
S
S
T
M
D
P
Q
F
G
P
---
A
W
I
G
F
A
H
S
F
A
-
I
E
G
E
H
D
Q
A
I
S
A
Y
T
T
A
A
R
L
F
Q
G
T
H
L
P
Y
L
F
L
G
M
Q
H
M
Q
L
G
N
I
L
L
A
N
E
Y
L
Q
S
S
Y
A
L
F
Q
Y
D
P
L
L
------
L
N
E
L
G
V
V
A
F
N
K
S
D
M
Q
T
A
I
N
H
F
Q
N
A
L
L
L
V
K
K
T
QSNE
K
P
W
A
A
T
W
A
N
L
G
H
A
Y
R
K
L
K
M
Y
D
A
A
I
D
A
L
N
Q
G
L
L
L
S
---
T
N
D
A
N
V
H
T
A
I
A
L
V
Y
L
H
K
K
I
P
G
L
A
I
T
H
L
H
E
S
L
A
--
I
S
P
N
E
I
M
A
S
D
L
L
K
R
A
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
53.73
26%
-92
- C- -
3ASG
-
?
A:
[87-208]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
I
A
Y
V
K
T
G
A
V
D
R
G
T
E
L
L
E
R
S
L
A
D
A
P
D
N
V
K
V
------
A
T
V
L
G
L
T
Y
V
Q
V
Q
K
Y
D
L
A
V
P
L
L
I
K
V
A
E
A
N
-------
P
I
N
F
N
V
R
F
R
L
G
V
A
L
K
N
L
G
R
F
D
E
A
I
D
S
F
K
I
A
L
G
L
R
---
P
N
E
G
K
V
H
R
A
I
A
F
S
Y
E
Q
M
G
R
H
E
E
A
L
P
H
F
K
K
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
53.15
26%
-90
- C3 -
3AS4
5
?
A:
[49-170]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
I
A
Y
V
K
T
G
A
V
D
R
G
T
E
L
L
E
R
S
L
A
D
A
P
D
N
V
K
V
------
A
T
V
L
G
L
T
Y
V
Q
V
Q
K
Y
D
L
A
V
P
L
L
I
K
V
A
E
A
N
-------
P
I
N
F
N
V
R
F
R
L
G
V
A
L
D
N
L
G
R
F
D
E
A
I
D
S
F
K
I
A
L
G
L
R
---
P
N
E
G
K
V
H
R
A
I
A
F
S
Y
E
Q
M
G
R
H
E
E
A
L
P
H
F
K
K
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
52.44
33%
-76
- C3 -
1NA0
8
?
B:
[12-125]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
Y
N
L
G
N
A
Y
Y
-
K
Q
G
D
Y
D
E
A
I
E
Y
Y
Q
K
A
L
E
L
D
P
N
N
A
E
A
W
Y
N
L
G
N
A
Y
Y
K
Q
G
D
Y
D
E
A
I
E
Y
Y
Q
K
A
L
E
L
D
P
N
N
A
E
A
------
W
Y
N
L
G
N
A
Y
Y
K
Q
G
D
Y
D
E
A
I
E
Y
Y
Q
K
A
L
E
L
D
-------
P
N
N
A
E
A
K
Q
N
L
G
N
A
K
Q
K
Q
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
52.13
22%
-87
- C3 -
4RG9
-
CDC27_HUMAN
A:
[588-774]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
H
D
I
A
I
K
F
F
Q
R
A
I
Q
V
D
P
N
Y
A
Y
---
A
Y
T
L
L
G
H
E
F
V
-
L
T
E
E
L
D
K
A
L
A
C
F
R
N
A
I
R
V
N
P
R
H
Y
N
A
W
Y
G
L
G
M
I
Y
Y
K
Q
E
K
F
S
L
A
E
M
H
F
Q
K
A
L
D
I
N
P
Q
S
S
V
L
------
L
C
H
I
G
V
V
Q
H
A
L
---------
L
N
K
A
I
V
I
D
-------
P
K
N
P
L
C
K
F
H
R
A
S
V
L
F
A
N
E
K
Y
K
S
A
L
Q
E
L
E
E
L
K
Q
I
V
---
P
K
E
S
L
V
Y
F
L
I
G
K
V
Y
K
K
L
G
Q
T
H
L
A
L
M
N
F
S
W
A
M
D
--
L
D
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
84
Fugue
51.82
16%
14
- C3 -
4BUJ
3
SKI3_YEAST
B:
[3-1436]
DS
M
S
D
I
K
Q
L
L
K
E
A
K
Q
E
L
T
N
RD
Y
E
E
T
I
E
I
S
E
K
V
L
K
L
D
PDN
Y
F
A
H
I
F
L
G
K
A
L
S
S
LPASN
N
V
S
S
N
R
N
L
E
R
A
T
N
H
Y
V
S
A
A
K
L
V
PDN
L
L
A
W
K
G
L
F
L
L
F
R
T
T
E
V
V
P
D
I
L
S
Y
D
E
Y
F
D
L
C
G
Q
Y
A
D
A
L
L
K
Q
EQ
V
E
L
I
N
D
I
K
L
L
K
K
T
H
PDC
Q
K
A
F
Y
Q
H
L
KPGS
L
M
A
E
T
IGRT
P
Q
D
A
L
L
N
L
I
K
I
L
S
N
I
E
T
T
E
I
G
K
T
L
S
Q
N
R
L
K
LKASDPD
Y
Q
I
K
L
N
S
F
S
W
E
I
I
K
N
SE
I
D
Q
L
Y
N
Q
L
V
N
I
LADD
Q
K
R
S
E
I
E
N
Q
W
L
E
Y
R
I
K
V
L
K
S
MP
L
D
V
K
K
D
F
F
T
K
V
K
E
M
V
E
D
M
V
L
V
NHQS
L
L
A
W
Q
K
Y
F
E
W
TDYEDLDNMDA
P
L
I
I
K
Y
F
K
K
FPKD
P
L
A
M
I
L
Y
S
W
L
S
SKLSKYD
I
K
S
L
E
SDDIEIGLL
E
E
E
V
V
T
V
L
T
E
N
I
V
K
C
KNN
I
L
A
H
R
I
L
C
Q
Y
Y
L
L
T
KEYEAA
L
P
Y
I
K
N
G
I
S
L
I
A
Y
N
I
K
D
LGVHL
P
L
T
K
R
E
F
S
L
D
L
A
T
V
Y
T
YVDAPKD
H
N
A
A
L
K
L
Y
D
N
I
L
S
GDFSN
I
Q
A
K
M
G
K
G
I
I
F
I
E
R
KNW
K
D
A
M
T
L
L
T
Q
V
H
E
Q
SPNN
L
E
V
L
S
E
L
S
W
S
K
A
H
M
GY
M
D
E
A
L
A
G
L
D
T
V
I
K
G
I
KGMD
L
R
S
I
D
F
R
A
L
N
L
W
R
Q
A
K
V
Y
I
M
K
H
A
S
A
K
Q
E
N
V
K
C
A
F
K
L
L
I
Q
S
I
K
I
L
D
T
F
A
P
---
G
F
S
T
L
G
D
I
Y
C
H
Y
Y
K
D
H
L
R
A
F
K
C
Y
F
K
A
F
D
L
D
A
G
D
Y
T
A
A
K
Y
I
T
E
T
Y
A
S
K
P
N
W
Q
A
A
S
S
I
A
S
R
L
I
K
G
E
K
A
K
A
E
L
R
S
NN
W
P
F
R
V
V
G
I
A
H
L
E
K
Q
E
E
S
D
S
I
E
W
F
Q
S
A
L
R
V
D
-------
P
N
D
V
E
S
W
V
G
L
G
Q
A
Y
H
A
C
G
R
I
E
A
S
I
K
V
F
D
K
A
I
Q
L
R
---
P
S
H
T
F
A
Q
Y
F
K
A
I
S
L
C
D
V
G
E
Y
L
E
S
L
D
I
L
E
K
V
C
Q
E
A
A
T
E
E
S
F
Q
I
G
L
V
E
V
L
M
R
C
S
L
D
L
Y
S
Q
GF
L
L
K
S
V
S
I
A
K
D
T
I
E
R
I
K
I
I
I
S
E
LKCENQQ
V
W
I
Y
L
S
Q
V
L
R
L
F
I
W
I
ESKVDTLP
V
E
S
L
V
S
I
F
E
N
S
QFSGS
E
E
I
D
S
V
DNIKIDTLLDSTTDD
N
V
S
I
A
C
K
F
L
I
L
A
S
K
Y
SVSDQK
F
T
D
I
AG
T
V
R
A
S
Y
W
Y
N
I
G
I
S
E
L
T
A
F
I
T
L
KE
P
Q
Y
R
D
A
A
I
F
A
F
K
K
S
I
Q
L
QSNT
S
E
T
W
I
G
L
G
I
A
T
MDIN
F
R
V
S
Q
H
C
F
I
K
A
T
A
L
EPKA
T
N
T
W
F
N
L
A
M
L
G
L
K
K
KD
T
E
F
A
Q
Q
V
L
N
K
L
Q
S
L
APQD
S
S
P
W
L
G
M
A
L
I
L
E
E
Q
GD
I
I
G
S
S
K
L
F
A
H
S
F
I
L
S
N
GRS
K
A
A
Q
F
M
Y
A
K
N
V
L
E
N
HINNGDDERD
I
E
T
V
E
K
L
T
T
A
S
I
A
L
E
Q
F
F
K
K
SPDS
Q
F
A
L
Q
C
A
L
L
T
L
E
R
L
HH
Y
E
N
A
N
E
L
A
N
R
L
I
G
I
L
E
K
K
F
E
K
TQD
E
R
E
L
F
N
F
A
I
I
K
G
Q
F
A
R
I
H
L
G
L
GN
F
E
L
S
I
E
N
A
D
L
S
Q
G
I
I
SESSD
E
K
S
M
K
T
K
I
S
N
H
I
C
L
G
L
S
Y
F
F
L
NDF
D
Q
T
L
N
Q
F
Q
E
L
L
S
I
S
KDS
K
H
L
V
V
L
I
A
K
V
L
Y
D
V
GE
S
D
T
K
E
I
A
L
Q
E
L
T
E
Y
I
A
T
SGADL
L
V
T
L
T
I
A
A
M
S
I
L
D
DK
R
E
D
L
S
I
I
L
E
E
L
K
A
LP
L
S
K
Q
I
I
DKHK
D
A
P
Y
L
I
E
E
I
T
K
R
L
YRNDTGK
Q
V
W
Q
R
S
A
Y
F
FPNN
L
K
V
W
E
R
LD
K
N
I
Q
R
R
I
A
SNGQ
N
K
V
T
A
E
E
M
S
K
L
Y
C
E
S
KN
L
R
S
I
Q
R
G
M
F
L
C
PWN
V
T
A
V
K
A
L
N
E
C
F
17
PsiBlast_PDB
51.24
26%
-88
- C3 -
3ASH
3
?
A:
[49-170]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
I
A
Y
V
K
T
G
A
V
D
R
G
T
E
L
L
E
R
S
L
A
D
A
P
D
N
V
K
V
------
A
T
V
L
G
L
T
Y
V
Q
V
Q
K
Y
D
L
A
V
P
L
L
I
K
V
A
E
A
N
-------
P
I
N
F
N
V
R
F
R
L
G
V
A
L
K
N
L
G
R
F
D
E
A
I
D
S
F
K
I
A
L
G
L
R
---
P
N
E
G
K
V
H
R
A
I
A
F
S
Y
E
Q
M
G
R
H
E
E
A
L
P
H
F
K
K
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
59
HHSearch
50.22
17%
-7
- C3 -
4R7S
7
?
A:
[16-220]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
G
D
L
V
S
A
E
E
S
L
K
A
A
M
R
K
E
P
A
N
P
L
N
Y
A
L
L
T
N
L
G
T
I
Q
R
-
R
Q
G
K
L
Q
E
A
L
I
S
Y
T
S
A
L
S
G
H
T
K
N
I
T
I
L
E
N
R
A
S
L
Y
T
E
L
G
E
T
E
K
A
L
N
D
Y
N
T
L
L
I
E
N
P
E
H
Q
E
A
------
L
Y
C
R
G
L
L
Y
I
Q
L
Q
N
Y
M
W
A
E
Q
D
F
D
K
I
L
E
V
N
-------
E
K
S
V
R
A
R
L
G
H
A
I
L
E
K
M
R
G
N
Y
D
E
S
E
R
I
F
N
Y
L
I
S
E
M
---
P
R
D
W
I
L
Y
E
G
R
A
D
L
Y
F
M
M
G
K
N
A
R
A
M
A
D
I
E
K
V
F
T
--
E
S
E
P
T
A
N
L
Y
V
L
R
G
K
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------