@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu27730: (2016-07-13 )
MDERLVSSEADNHESVIEQSLRPQNLAQYIGQHKVKENLRVFIDAAKMRQETLDHVLLYGPPGLGKTTLASIVANEMGVELRTTSGPAIERPGDLAAILTALEPGDVLFIDEIHRLHRSIEEVLYPAMEDFCLDIVIGKGPSARSVRLDLPPFTLVGATTRVGLLTAPLRDRFGVMSRLEYYTQEELADIVTRTADVFEVEIDKPSALEIARRSRGTPRVANRLLRRVRDFAQVLGDSRITEDISQNALERLQVDRLGLDHIDHKLLMGMIEKFNGGPVGLDTISATIGEESHTIEDVYEPYLLQIGFIQRTPRGRIVTPAVYHHFQMEAPRYD
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70.......--------.80.-------------------.......-----90....--....-100------....-----....110.......120.......130.......140.......150.......160--.......170.......180.......190.....-------..200.......210.......220.......230.....--..240.......250.......260........270......-.280.......290...---....300.......310.......320.......330..--
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MDERLVSSEAD
N
H
E
S
V
I
E
QSL
R
P
Q
N
L
A
Q
Y
I
G
Q
H
K
V
K
E
N
L
R
V
F
I
D
A
A
K
M
R
Q
E
T
LD
H
V
L
L
YGPPGL
G
K
T
T
L
A
S
I
V
A
N
EMG--------
V
E
L
R-------------------TTSGPAI-----ERP
G
D
L
--
A
A
I
L
-
T
-A------LEPG-----
D
V
L
F
I
D
E
I
H
R
L
H
R
S
I
E
E
V
L
Y
P
A
M
E
D
F
C
L
D
I
V
IGKGPSA
R
S
V
R
LDLPP
F
T
L
VGA
T
T
R
V
--
G
L
L
TA
P
L
R
D
R
F
G
V
M
S
R
L
E
Y
Y
T
Q
E
E
L
A
D
I
V
TRTA
D
V
-------
F
E
V
EIDKP
S
A
L
E
I
A
R
RSRGT
P
R
V
A
N
R
L
L
R
R
V
R
D
F
A
Q
V
LGD--
S
R
I
T
E
D
I
S
Q
N
A
L
E
R
L
Q
V
D
RL
G
L
D
H
-
I
D
H
K
L
L
M
G
M
I
E
KFNGGP-V
G
L
D
T
I
S
A
TIGEESH
T
I
---
E
D
V
Y
E
P
Y
L
L
Q
I
G
F
I
Q
RTPRGRIV
T
P
A
V
Y
H
H
F
QMEAPRYD--
4
PsiBlast_PDB
89.17
56%
-132
- C2 -
1IN8
1
RUVB_THEMA
A:
[17-329]
------------------
Q
F
L
R
P
K
S
L
D
E
F
I
G
Q
E
N
V
K
K
K
L
S
L
A
L
E
A
A
K
M
R
G
E
V
L
D
H
V
L
L
A
G
P
P
G
L
G
K
T
T
L
A
H
I
I
A
S
E
L
Q
--------
T
N
I
H
-------------------
V
T
S
G
P
V
L
-----
V
K
Q
G
D
M
--
A
A
I
L
-
T
-
S
------
L
E
R
G
-----
D
V
L
F
I
D
E
I
H
R
L
N
K
A
V
E
E
L
L
Y
S
A
I
E
D
F
Q
I
D
---------------
I
Q
P
F
T
L
V
G
A
T
V
R
S
--
G
L
L
S
S
P
L
R
S
R
F
G
I
I
L
E
L
D
F
Y
T
V
K
E
L
K
E
I
I
K
R
A
A
S
L
-------
M
D
V
E
I
E
D
A
A
A
E
M
I
A
K
R
S
R
G
T
P
R
I
A
I
R
L
T
K
R
V
R
D
M
L
T
V
V
K
A
--
D
R
I
N
T
D
I
V
L
K
T
M
E
V
L
N
I
D
D
E
G
L
D
E
-
F
D
R
K
I
L
K
T
I
I
E
I
Y
R
G
G
P
-
V
G
L
N
A
L
A
A
S
L
G
V
E
A
D
T
L
---
S
E
V
Y
E
P
Y
L
L
Q
A
G
F
L
A
R
T
P
R
G
R
I
V
T
E
K
A
Y
K
H
L
K
Y
E
V
P
-----
112
HHSearch
88.63
57%
-131
- C2 -
1IN4
5
RUVB_THEMA
A:
[18-329]
-------------------
F
L
R
P
K
S
L
D
E
F
I
G
Q
E
N
V
K
K
K
L
S
L
A
L
E
A
A
K
M
R
G
E
V
L
D
H
V
L
L
A
G
P
P
G
L
G
K
T
T
L
A
H
I
I
A
S
E
L
Q
--------
T
N
I
H
-------------------
V
T
S
G
P
V
L
-----
V
K
Q
G
D
M
--
A
A
I
L
-
T
-
S
------
L
E
R
G
-----
D
V
L
F
I
D
E
I
H
R
L
N
K
A
V
E
E
L
L
Y
S
A
I
E
D
F
Q
I
D
---------------
I
Q
P
F
T
L
V
G
A
T
T
R
S
--
G
L
L
S
S
P
L
R
S
R
F
G
I
I
L
E
L
D
F
Y
T
V
K
E
L
K
E
I
I
K
R
A
A
S
L
-------
M
D
V
E
I
E
D
A
A
A
E
M
I
A
K
R
S
R
G
T
P
R
I
A
I
R
L
T
K
R
V
R
D
M
L
T
V
V
K
A
--
D
R
I
N
T
D
I
V
L
K
T
M
E
V
L
N
I
D
D
E
G
L
D
E
-
F
D
R
K
I
L
K
T
I
I
E
I
Y
R
G
G
P
-
V
G
L
N
A
L
A
A
S
L
G
V
E
A
D
T
L
---
S
E
V
Y
E
P
Y
L
L
Q
A
G
F
L
A
R
T
P
R
G
R
I
V
T
E
K
A
Y
K
H
L
K
Y
E
V
P
-----
1
PsiBlast_PDB
88.51
56%
-130
- C2 -
1IN4
5
RUVB_THEMA
A:
[17-329]
------------------
Q
F
L
R
P
K
S
L
D
E
F
I
G
Q
E
N
V
K
K
K
L
S
L
A
L
E
A
A
K
M
R
G
E
V
L
D
H
V
L
L
A
G
P
P
G
L
G
K
T
T
L
A
H
I
I
A
S
E
L
Q
--------
T
N
I
H
-------------------
V
T
S
G
P
V
L
-----
V
K
Q
G
D
M
--
A
A
I
L
-
T
-
S
------
L
E
R
G
-----
D
V
L
F
I
D
E
I
H
R
L
N
K
A
V
E
E
L
L
Y
S
A
I
E
D
F
Q
I
D
---------------
I
Q
P
F
T
L
V
G
A
T
T
R
S
--
G
L
L
S
S
P
L
R
S
R
F
G
I
I
L
E
L
D
F
Y
T
V
K
E
L
K
E
I
I
K
R
A
A
S
L
-------
M
D
V
E
I
E
D
A
A
A
E
M
I
A
K
R
S
R
G
T
P
R
I
A
I
R
L
T
K
R
V
R
D
M
L
T
V
V
K
A
--
D
R
I
N
T
D
I
V
L
K
T
M
E
V
L
N
I
D
D
E
G
L
D
E
-
F
D
R
K
I
L
K
T
I
I
E
I
Y
R
G
G
P
-
V
G
L
N
A
L
A
A
S
L
G
V
E
A
D
T
L
---
S
E
V
Y
E
P
Y
L
L
Q
A
G
F
L
A
R
T
P
R
G
R
I
V
T
E
K
A
Y
K
H
L
K
Y
E
V
P
-----
3
PsiBlast_PDB
87.99
56%
-131
- C2 -
1IN6
2
RUVB_THEMA
A:
[17-329]
------------------
Q
F
L
R
P
K
S
L
D
E
F
I
G
Q
E
N
V
K
K
K
L
S
L
A
L
E
A
A
K
M
R
G
E
V
L
D
H
V
L
L
A
G
P
P
G
L
G
R
T
T
L
A
H
I
I
A
S
E
L
Q
--------
T
N
I
H
-------------------
V
T
S
G
P
V
L
-----
V
K
Q
G
D
M
--
A
A
I
L
-
T
-
S
------
L
E
R
G
-----
D
V
L
F
I
D
E
I
H
R
L
N
K
A
V
E
E
L
L
Y
S
A
I
E
D
F
Q
I
D
-------------
I
D
I
Q
P
F
T
L
V
G
A
T
T
R
S
--
G
L
L
S
S
P
L
R
S
R
F
G
I
I
L
E
L
D
F
Y
T
V
K
E
L
K
E
I
I
K
R
A
A
S
L
-------
M
D
V
E
I
E
D
A
A
A
E
M
I
A
K
R
S
R
G
T
P
R
I
A
I
R
L
T
K
R
V
R
D
M
L
T
V
V
K
A
--
D
R
I
N
T
D
I
V
L
K
T
M
E
V
L
N
I
D
D
E
G
L
D
E
-
F
D
R
K
I
L
K
T
I
I
E
I
Y
R
G
G
P
-
V
G
L
N
A
L
A
A
S
L
G
V
E
A
D
T
L
---
S
E
V
Y
E
P
Y
L
L
Q
A
G
F
L
A
R
T
P
R
G
R
I
V
T
E
K
A
Y
K
H
L
K
Y
E
V
P
-----
6
PsiBlast_PDB
87.58
56%
-132
- C2 -
1J7K
4
RUVB_THEMA
A:
[19-329]
--------------------
L
R
P
K
S
L
D
E
F
I
G
Q
E
N
V
K
K
K
L
S
L
A
L
E
A
A
K
M
R
G
E
V
L
D
H
V
L
L
A
G
P
P
G
L
G
K
T
T
L
A
H
I
I
A
S
E
L
Q
--------
T
N
I
H
-------------------
V
T
S
G
P
V
L
-----
V
K
Q
G
D
M
--
A
A
I
L
-
T
-
S
------
L
E
R
G
-----
D
V
L
F
I
D
E
I
H
R
L
N
K
A
V
E
E
L
L
Y
S
A
I
E
D
F
Q
I
D
I
------------
I
D
I
Q
P
F
T
L
V
G
A
T
T
R
S
--
G
L
L
S
S
P
L
R
S
R
F
G
I
I
L
E
L
D
F
Y
T
V
K
E
L
K
E
I
I
K
R
A
A
S
L
-------
M
D
V
E
I
E
D
A
A
A
E
M
I
A
K
R
S
R
G
T
G
R
I
A
I
R
L
T
K
R
V
R
D
M
L
T
V
V
K
A
--
D
R
I
N
T
D
I
V
L
K
T
M
E
V
L
N
I
D
D
E
G
L
D
E
-
F
D
R
K
I
L
K
T
I
I
E
I
Y
R
G
G
P
-
V
G
L
N
A
L
A
A
S
L
G
V
E
A
D
T
L
---
S
E
V
Y
E
P
Y
L
L
Q
A
G
F
L
A
R
T
P
R
G
R
I
V
T
E
K
A
Y
K
H
L
K
Y
E
V
P
-----
2
PsiBlast_PDB
87.43
56%
-124
- C2 -
1IN5
1
RUVB_THEMA
A:
[17-329]
------------------
Q
F
L
R
P
K
S
L
D
E
F
I
G
Q
E
N
V
K
K
K
L
S
L
A
L
E
A
A
K
M
R
G
E
V
L
D
H
V
L
L
A
G
P
P
G
L
G
K
T
T
L
A
H
I
I
A
S
E
L
Q
--------
T
N
I
H
-------------------
V
T
S
G
P
V
L
-----
V
K
Q
G
D
M
--
A
A
I
L
-
T
-
S
------
L
E
R
G
-----
D
V
L
F
I
D
E
I
H
R
L
N
K
A
V
E
E
L
L
Y
S
A
I
E
D
F
Q
I
D
I
M
------------
D
I
Q
P
F
T
L
V
G
S
T
T
R
S
--
G
L
L
S
S
P
L
R
S
R
F
G
I
I
L
E
L
D
F
Y
T
V
K
E
L
K
E
I
I
K
R
A
A
S
L
-------
M
D
V
E
I
E
D
A
A
A
E
M
I
A
K
R
S
R
G
T
P
R
I
A
I
R
L
T
K
R
V
R
D
M
L
T
V
V
K
A
--
D
R
I
N
T
D
I
V
L
K
T
M
E
V
L
N
I
D
D
E
G
L
D
E
-
F
D
R
K
I
L
K
T
I
I
E
I
Y
R
G
G
P
-
V
G
L
N
A
L
A
A
S
L
G
V
E
A
D
T
L
---
S
E
V
Y
E
P
Y
L
L
Q
A
G
F
L
A
R
T
P
R
G
R
I
V
T
E
K
A
Y
K
H
L
K
Y
E
V
P
-----
5
PsiBlast_PDB
86.62
56%
-132
- C2 -
1IN7
3
RUVB_THEMA
A:
[17-329]
------------------
Q
F
L
R
P
K
S
L
D
E
F
I
G
Q
E
N
V
K
K
K
L
S
L
A
L
E
A
A
K
M
R
G
E
V
L
D
H
V
L
L
A
G
P
P
G
L
G
K
T
T
L
A
H
I
I
A
S
E
L
Q
--------
T
N
I
H
-------------------
V
T
S
G
P
V
L
-----
V
K
Q
G
D
M
--
A
A
I
L
-
T
-
S
------
L
E
R
G
-----
D
V
L
F
I
D
E
I
H
R
L
N
K
A
V
E
E
L
L
Y
S
A
I
E
D
F
Q
I
D
---------------
I
Q
P
F
T
L
V
G
A
T
T
R
S
--
G
L
L
S
S
P
L
R
S
A
F
G
I
I
L
E
L
D
F
Y
T
V
K
E
L
K
E
I
I
K
R
A
A
S
L
-------
M
D
V
E
I
E
D
A
A
A
E
M
I
A
K
R
S
R
G
T
P
R
I
A
I
R
L
T
K
R
V
R
D
M
L
T
V
V
K
A
--
D
R
I
N
T
D
I
V
L
K
T
M
E
V
L
N
I
D
D
E
G
L
D
E
-
F
D
R
K
I
L
K
T
I
I
E
I
Y
R
G
G
P
-
V
G
L
N
A
L
A
A
S
L
G
V
E
A
D
T
L
---
S
E
V
Y
E
P
Y
L
L
Q
A
G
F
L
A
R
T
P
R
G
R
I
V
T
E
K
A
Y
K
H
L
K
Y
E
V
P
-----
110
HHSearch
84.48
53%
-118
- C2 -
3PFI
1
RUVB_CAMJE
A:
[23-332]
--------------------
L
R
P
S
N
F
D
G
Y
I
G
Q
E
S
I
K
K
N
L
N
V
F
I
A
A
A
K
K
R
N
E
C
L
D
H
I
L
F
S
G
P
A
G
L
G
K
T
T
L
A
N
I
I
S
Y
E
M
S
--------
A
N
I
K
-------------------
T
T
A
A
P
M
I
-----
E
K
S
G
D
L
--
A
A
I
L
-
T
-
N
------
L
S
E
G
-----
D
I
L
F
I
D
E
I
H
R
L
S
P
A
I
E
E
V
L
Y
P
A
M
E
D
Y
R
L
---------
A
Q
T
I
K
I
D
L
P
K
F
T
L
I
G
A
T
T
R
A
--
G
M
L
S
N
P
L
R
D
R
F
G
M
Q
F
R
L
E
F
Y
K
D
S
E
L
A
L
I
L
Q
K
A
A
L
K
-------
L
N
K
T
C
E
E
K
A
A
L
E
I
A
K
R
S
R
S
T
P
R
I
A
L
R
L
L
K
R
V
R
D
F
A
D
V
N
D
E
--
E
I
I
T
E
K
R
A
N
E
A
L
N
S
L
G
V
N
E
L
G
F
D
A
-
M
D
L
R
Y
L
E
L
L
T
A
-
A
K
Q
K
P
-
I
G
L
A
S
I
A
A
A
L
S
E
D
E
N
T
I
---
E
D
V
I
E
P
Y
L
L
A
N
G
Y
I
E
R
T
A
K
G
R
I
A
S
A
K
S
Y
S
A
L
K
L
N
Y
E
-----
10
PsiBlast_PDB
84.37
52%
-121
- C2 -
3PFI
1
RUVB_CAMJE
A:
[23-329]
--------------------
L
R
P
S
N
F
D
G
Y
I
G
Q
E
S
I
K
K
N
L
N
V
F
I
A
A
A
K
K
R
N
E
C
L
D
H
I
L
F
S
G
P
A
G
L
G
K
T
T
L
A
N
I
I
S
Y
E
M
S
--------
A
N
I
K
-------------------
T
T
A
A
P
M
I
-----
E
K
S
G
D
L
--
A
A
I
L
-
T
-
N
------
L
S
E
G
-----
D
I
L
F
I
D
E
I
H
R
L
S
P
A
I
E
E
V
L
Y
P
A
M
E
D
Y
R
L
---------
A
Q
T
I
K
I
D
L
P
K
F
T
L
I
G
A
T
T
R
A
--
G
M
L
S
N
P
L
R
D
R
F
G
M
Q
F
R
L
E
F
Y
K
D
S
E
L
A
L
I
L
Q
K
A
A
L
K
-------
L
N
K
T
C
E
E
K
A
A
L
E
I
A
K
R
S
R
S
T
P
R
I
A
L
R
L
L
K
R
V
R
D
F
A
D
V
N
D
E
--
E
I
I
T
E
K
R
A
N
E
A
L
N
S
L
G
V
N
E
L
G
F
D
A
-
M
D
L
R
Y
L
E
-
L
L
T
A
A
K
Q
K
P
-
I
G
L
A
S
I
A
A
A
L
S
E
D
E
N
T
I
---
E
D
V
I
E
P
Y
L
L
A
N
G
Y
I
E
R
T
A
K
G
R
I
A
S
A
K
S
Y
S
A
L
K
L
--------
7
PsiBlast_PDB
78.62
59%
-22
- C2 -
1IXS
1
RUVB_THET8
B:
[5-317]
-------------------
A
L
R
P
K
T
L
D
E
Y
I
G
Q
E
R
L
K
Q
K
L
R
V
Y
L
E
A
A
K
A
R
K
E
P
L
E
H
L
L
L
F
G
P
P
G
L
G
K
T
T
L
A
H
V
I
A
H
E
L
G
--------
V
N
L
R
-------------------
V
T
S
G
P
A
I
-----
E
K
P
G
D
L
--
A
A
I
L
A
N
-
S
------
L
E
E
G
-----
D
I
L
F
I
D
E
I
H
R
L
S
R
Q
A
E
E
H
L
Y
P
A
M
E
D
F
V
M
D
I
V
I
G
Q
G
P
A
A
R
T
I
R
L
E
L
P
R
F
T
L
I
G
A
T
T
R
P
--
G
L
I
T
A
P
L
L
S
R
F
G
I
V
E
H
L
E
Y
Y
T
P
E
E
L
A
Q
G
V
M
R
D
A
R
L
-------
L
G
V
R
I
T
E
E
A
A
L
E
I
G
R
R
S
R
G
T
M
R
V
A
K
R
L
F
R
R
V
R
D
F
A
Q
V
A
G
E
--
E
V
I
T
R
E
R
A
L
E
A
L
A
A
L
G
L
D
E
L
G
L
E
K
-
R
D
R
E
I
L
E
V
L
I
L
R
F
G
G
G
P
-
V
G
L
A
T
L
A
T
A
L
S
E
D
P
G
T
L
---
E
E
V
H
E
P
Y
L
I
R
Q
G
L
L
K
R
T
P
R
G
R
V
A
T
E
L
A
Y
R
H
L
G
Y
P
P
P
-----
111
HHSearch
75.90
59%
-12
* C2 *
1HQC
2
RUVB_THET8
A:
[5-317]
-------------------
A
L
R
P
K
T
L
D
E
Y
I
G
Q
E
R
L
K
Q
K
L
R
V
Y
L
E
A
A
K
A
R
K
E
P
L
E
H
L
L
L
F
G
P
P
G
L
G
K
T
T
L
A
H
V
I
A
H
E
L
G
--------
V
N
L
R
-------------------
V
T
S
G
P
A
I
-----
E
K
P
G
D
L
--
A
A
I
L
-
A
N
S
------
L
E
E
G
-----
D
I
L
F
I
D
E
I
H
R
L
S
R
Q
A
E
E
H
L
Y
P
A
M
E
D
F
V
M
D
I
V
I
G
Q
G
P
A
A
R
T
I
R
L
E
L
P
R
F
T
L
I
G
A
T
T
R
P
--
G
L
I
T
A
P
L
L
S
R
F
G
I
V
E
H
L
E
Y
Y
T
P
E
E
L
A
Q
G
V
M
R
D
A
R
L
-------
L
G
V
R
I
T
E
E
A
A
L
E
I
G
R
R
S
R
G
T
M
R
V
A
K
R
L
F
R
R
V
R
D
F
A
Q
V
A
G
E
--
E
V
I
T
R
E
R
A
L
E
A
L
A
A
L
G
L
D
E
L
G
L
E
K
-
R
D
R
E
I
L
E
V
L
I
L
R
F
G
G
G
P
-
V
G
L
A
T
L
A
T
A
L
S
E
D
P
G
T
L
---
E
E
V
H
E
P
Y
L
I
R
Q
G
L
L
K
R
T
P
R
G
R
V
P
T
E
L
A
Y
R
H
L
G
Y
P
P
P
-----
8
PsiBlast_PDB
75.74
59%
-12
- C2 -
1HQC
2
RUVB_THET8
A:
[5-317]
-------------------
A
L
R
P
K
T
L
D
E
Y
I
G
Q
E
R
L
K
Q
K
L
R
V
Y
L
E
A
A
K
A
R
K
E
P
L
E
H
L
L
L
F
G
P
P
G
L
G
K
T
T
L
A
H
V
I
A
H
E
L
G
--------
V
N
L
R
-------------------
V
T
S
G
P
A
I
-----
E
K
P
G
D
L
--
A
A
I
L
A
N
-
S
------
L
E
E
G
-----
D
I
L
F
I
D
E
I
H
R
L
S
R
Q
A
E
E
H
L
Y
P
A
M
E
D
F
V
M
D
I
V
I
G
Q
G
P
A
A
R
T
I
R
L
E
L
P
R
F
T
L
I
G
A
T
T
R
P
--
G
L
I
T
A
P
L
L
S
R
F
G
I
V
E
H
L
E
Y
Y
T
P
E
E
L
A
Q
G
V
M
R
D
A
R
L
-------
L
G
V
R
I
T
E
E
A
A
L
E
I
G
R
R
S
R
G
T
M
R
V
A
K
R
L
F
R
R
V
R
D
F
A
Q
V
A
G
E
--
E
V
I
T
R
E
R
A
L
E
A
L
A
A
L
G
L
D
E
L
G
L
E
K
-
R
D
R
E
I
L
E
V
L
I
L
R
F
G
G
G
P
-
V
G
L
A
T
L
A
T
A
L
S
E
D
P
G
T
L
---
E
E
V
H
E
P
Y
L
I
R
Q
G
L
L
K
R
T
P
R
G
R
V
P
T
E
L
A
Y
R
H
L
G
Y
P
P
P
-----
130
Fugue
75.58
59%
-12
- C2 -
1HQC
2
RUVB_THET8
A:
[5-318]
-------------------
A
L
R
P
K
T
L
D
E
Y
I
G
Q
E
R
L
K
Q
K
L
R
V
Y
L
E
A
A
K
A
R
K
E
P
L
E
H
L
L
L
F
G
P
P
G
L
G
K
T
T
L
A
H
V
I
A
H
E
L
G
--------
V
N
L
R
-------------------
V
T
S
G
P
A
I
-----
E
K
P
G
D
L
--
A
A
I
L
-
A
-
N
S-----
L
E
E
G
-----
D
I
L
F
I
D
E
I
H
R
L
S
R
Q
A
E
E
H
L
Y
P
A
M
E
D
F
V
M
D
I
V
I
G
Q
G
P
A
A
R
T
I
R
L
E
L
P
R
F
T
L
I
G
A
T
T
R
P
--
G
L
I
T
A
P
L
L
S
R
F
G
I
V
E
H
L
E
Y
Y
T
P
E
E
L
A
Q
G
V
M
R
D
A
R
L
-------
L
G
V
R
I
T
E
E
A
A
L
E
I
G
R
R
S
R
G
T
M
R
V
A
K
R
L
F
R
R
V
R
D
F
A
Q
V
A
G
E
--
E
V
I
T
R
E
R
A
L
E
A
L
A
A
L
G
L
D
E
L
G
L
E
K
-
R
D
R
E
I
L
E
V
L
I
L
R
F
G
G
G
P
-
V
G
L
A
T
L
A
T
A
L
S
E
D
P
G
T
L
---
E
E
V
H
E
P
Y
L
I
R
Q
G
L
L
K
R
T
P
R
G
R
V
P
T
E
L
A
Y
R
H
L
G
Y
P
P
P
V
----
21
PsiBlast_CBE
74.97
59%
-12
- C2 -
1HQC
2
RUVB_THET8
B:
[5-317]
-------------------
A
L
R
P
K
T
L
D
E
Y
I
G
Q
E
R
L
K
Q
K
L
R
V
Y
L
E
A
A
K
A
R
K
E
P
L
E
H
L
L
L
F
G
P
P
G
L
G
K
T
T
L
A
H
V
I
A
H
E
L
G
--------
V
N
L
R
-------------------
V
T
S
G
P
A
I
-----
E
K
P
G
D
L
--
A
A
I
L
A
N
-
S
------
L
E
E
G
-----
D
I
L
F
I
D
E
I
H
R
L
S
R
Q
A
E
E
H
L
Y
P
A
M
E
D
F
V
M
D
I
V
I
G
Q
G
P
A
A
R
T
I
R
L
E
L
P
R
F
T
L
I
G
A
T
T
R
P
--
G
L
I
T
A
P
L
L
S
R
F
G
I
V
E
H
L
E
Y
Y
T
P
E
E
L
A
Q
G
V
M
R
D
A
R
L
-------
L
G
V
R
I
T
E
E
A
A
L
E
I
G
R
R
S
R
G
T
M
R
V
A
K
R
L
F
R
R
V
R
D
F
A
Q
V
A
G
E
--
E
V
I
T
R
E
R
A
L
E
A
L
A
A
L
G
L
D
E
L
G
L
E
K
-
R
D
R
E
I
L
E
V
L
I
L
R
F
G
G
G
P
-
V
G
L
A
T
L
A
T
A
L
S
E
D
P
G
T
L
---
E
E
V
H
E
P
Y
L
I
R
Q
G
L
L
K
R
T
P
R
G
R
V
P
T
E
L
A
Y
R
H
L
G
Y
P
P
P
-----
9
PsiBlast_PDB
72.15
59%
-26
- C2 -
1IXR
1
RUVB_THET8
C:
[5-312]
-------------------
A
L
R
P
K
T
L
D
E
Y
I
G
Q
E
R
L
K
Q
K
L
R
V
Y
L
E
A
A
K
A
R
K
E
P
L
E
H
L
L
L
F
G
P
P
G
L
G
K
T
T
L
A
H
V
I
A
H
E
L
G
--------
V
N
L
R
-------------------
V
T
S
G
P
A
I
-----
E
K
P
G
D
L
--
A
A
I
L
A
N
-
S
------
L
E
E
G
-----
D
I
L
F
I
D
E
I
H
R
L
S
R
Q
A
E
E
H
L
Y
P
A
M
E
D
F
V
M
D
I
V
I
G
Q
G
P
A
A
R
T
I
R
L
E
L
P
R
F
T
L
I
G
A
T
T
R
P
--
G
L
I
T
A
P
L
L
S
R
F
G
I
V
E
H
L
E
Y
Y
T
P
E
E
L
A
Q
G
V
M
R
D
A
R
L
-------
L
G
V
R
I
T
E
E
A
A
L
E
I
G
R
R
S
R
G
T
M
R
V
A
K
R
L
F
R
R
V
R
D
F
A
Q
V
A
G
E
--
E
V
I
T
R
E
R
A
L
E
A
L
A
A
L
G
L
D
E
L
G
L
E
K
-
R
D
R
E
I
L
E
V
L
I
L
R
F
G
G
G
P
-
V
G
L
A
T
L
A
T
A
L
S
E
D
P
G
T
L
---
E
E
V
H
E
P
Y
L
I
R
Q
G
L
L
K
R
T
P
R
G
R
V
A
T
E
L
A
R
R
H
L
----------
117
HHSearch
42.66
22%
-27
- C2 -
1NJG
3
DPO3X_ECOLI
A:
[11-235]
--------------
Q
V
L
A
R
K
W
R
P
Q
T
F
A
D
V
V
G
Q
E
H
V
L
T
A
L
A
N
G
L
S
L
----
G
R
I
H
H
A
Y
L
F
S
G
T
R
G
V
G
K
T
S
I
A
R
L
L
A
K
G
L
N
--------
C
E
T
G
ITATPCGVC
D
N
C
R
E
I
E
Q
GR
F
V
D
L
I
E
I
D
AASR
T
K
V
E
D
T
--
R
D
L
L
-
D
-
N
VQYAPA
R
G
R
F
-----
K
V
Y
L
I
D
E
V
H
M
L
S
R
H
S
F
N
A
L
L
K
T
L
E
E
P
P
------------------
E
H
V
K
F
L
L
A
T
T
D
P
--
Q
K
L
P
V
T
I
L
S
R
C
-
L
Q
F
H
L
K
A
L
D
V
E
Q
I
R
H
Q
L
E
H
I
L
N
E
-------
E
H
I
A
H
E
P
R
A
L
Q
L
L
A
R
A
A
E
G
S
L
R
D
A
L
S
L
T
D
Q
A
I
A
S
G
---------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
42.44
55%
-175
- C4 -
1R7R
1
TERA_MOUSE
A:
[241-310]
-------------------------------------------------------
I
L
L
Y
G
P
P
G
T
G
K
T
L
I
A
R
A
V
A
N
E
T
G
--------
A
F
F
F
-------------------
L
I
N
G
P
E
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
131
Fugue
40.79
17%
1
- C2 -
1IQP
1
RFCS_PYRFU
A:
[2-327]
---
S
E
E
I
R
E
V
K
V
L
E
K
P
W
V
E
K
Y
R
P
Q
R
L
D
D
I
V
G
Q
E
H
I
V
K
R
L
K
H
Y
V
K
T
-----
G
S
M
P
H
L
L
F
A
G
P
P
G
V
G
K
T
T
A
A
L
A
L
A
R
E
L
F
GENWRHN
F
L
E
L
N
-------------------
A
S
D
E
R
G
I
-----
N
V
I
R
E
K
--
V
K
E
F
-
A
-
R
------
T
K
P
I
GGAS
F
K
I
I
F
L
D
E
A
D
A
L
T
Q
D
A
Q
Q
A
L
R
R
T
M
E
M
F
------------------
S
S
N
V
R
F
I
L
S
C
N
Y
S
--
S
K
I
I
E
P
I
Q
S
R
C
A
I
F
R
-
F
R
P
L
R
D
E
D
I
A
K
R
L
R
Y
I
A
E
N
-------
E
G
L
E
L
T
E
E
G
L
Q
A
I
L
Y
I
A
E
G
D
M
R
R
A
I
N
I
L
Q
A
A
A
A
L
D
K
K
I
T
D
--
E
N
V
F
M
V
A
S
R
A
R
P
E
D
I
R
E
M
M
L
L
A
L
K
-
G
N
F
L
K
A
R
E
K
L
R
E
I
L
L
K
Q
G
L
S
G
E
D
V
L
V
Q
M
H
K
E
V
F
N
L
PIE
E
P
K
K
V
L
L
A
D
K
I
G
E
Y
N
F
R
L
V
E
G
A
N
E
I
I
Q
L
E
A
L
L
A
Q
F
T
L
I
G
K
K
115
HHSearch
39.23
26%
-31
- C2 -
3PVS
1
RARA_ECOLI
A:
[14-255]
--------------
Q
P
L
A
A
R
M
R
P
E
N
L
A
Q
Y
I
G
Q
Q
H
L
L
A
A
G
K
P
L
P
R
A
I
E
A
-
G
-
H
L
H
S
M
I
L
W
G
P
P
G
T
G
K
T
T
L
A
E
V
I
A
R
Y
A
N
--------
A
D
V
E
-------------------
R
I
S
A
V
T
S
-----
G
-
V
K
E
I
--
R
E
A
I
-
E
-
R
A
R
Q
N
R
N
A
G
R
R
-----
T
I
L
F
V
D
E
V
H
R
F
------
A
F
L
P
H
I
E
D
--------------------
G
T
I
T
F
I
G
A
T
T
E
N
PS
F
E
L
N
S
A
L
L
S
R
A
-
R
V
Y
L
L
K
S
L
S
T
E
D
I
E
Q
V
L
T
Q
A
M
E
D
KTRGYGG
Q
D
I
V
L
P
D
E
T
R
R
A
I
A
E
L
V
N
G
D
A
R
R
A
L
N
T
L
E
M
M
A
D
M
A
E
V
D
D
S
GK
R
V
L
K
P
E
L
L
T
E
I
A
G
-------------------------------------------------------------------------------------------
135
Fugue
38.78
20%
-7
- C2 -
5C3C
1
?
B:
[26-281]
------------------------
K
E
P
Y
Y
---
R
A
V
Q
D
E
I
E
L
Y
R
A
G
Y
E
A
R
I
P
----
M
M
L
K
G
P
T
G
C
G
K
S
R
F
V
E
H
M
A
W
K
L
N
--------
R
P
L
I
-------------------
T
I
A
C
N
E
D
-----
M
T
A
S
D
L
VD
G
P
L
T
-
V
-
A
------
A
R
I
G
-----
A
I
C
Y
L
D
E
I
V
E
A
R
Q
D
T
I
V
V
I
H
P
L
T
-
D
H
R
R
V
L
P
L
E
K
K
G
E
L
V
E
A
H
---
P
D
F
Q
I
V
I
S
Y
N
D
-----
L
K
Q
S
T
K
Q
R
F
G
A
L
D
-
F
D
Y
P
K
P
D
I
E
A
E
I
V
S
H
E
A
G
V
-------
D
K
D
T
A
E
K
--
L
V
Q
I
A
Q
K
A
R
N
---------------------------------------
L
K
G
H
G
L
D
E
G
L
S
T
R
L
L
V
Y
A
G
K
L
I
A
K
G
V
-
D
A
R
A
A
C
T
M
T
L
---------------------------
V
N
P
I
T
D
D
V
D
M
R
D
A
L
D
T
V
V
K
T
F
F
--