@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu28640: (2016-07-15 )
MEEKLKQLEQEALEQVEAASSLKVVNDIRVQYLGKKGPITEVLRGMGKLSAEERPKMGALANEVRERIANAIADKNEKLEEEEMKQKLAGQTIDVTLPGNPVAVGGRHPLTVVIEEIEDLFIGMGYTVEEGPEVETDYYNFESLNLPKEHPARDMQDSFYITEETLMRTQTSPVQTRTMEKHEGKGPVKIICPGKVYRRDNDDATHSHQFMQIEGLVVDKNISMSDLKGTLELVAKKMFGQDREIRLRPSFFPFTEPSVEVDVTCFKCGGNGCSVCKGTGWIEILGAGMVHPNVLKMAGFDPKEYQGFAFGMGVERIAMLKYGIDDIRHFYTNDVRFISQFKQA
Atome Classification :
(32 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120...--------.---------...130........140.......150.......160.---------------.---------------.....170.......180.......190.......200.......210......-----------------------------------.220..-----------------------------------.....230.......240.......250.......260.......270.......280.......290......-------.300--.---------...-...310.......320.......330.......340..---------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
E
E
K
L
K
Q
L
E
Q
E
A
L
E
Q
V
E
A
A
S
SL
K
V
V
N
D
I
R
V
Q
YLGKKG
P
I
T
E
V
L
R
G
M
G
KL
S
A
E
ERPKM
G
A
L
A
N
E
V
R
E
R
I
A
N
A
IADKNEKL
E
E
E
E
M
K
Q
K
LAG
Q
T
I
D
V
TLPGN
P
V
AVGGRH
P
L
T
V
V
I
E
E
I
E
D
L
F
IGMG--------Y---------TVEEG-PEVETDYYNFESLNLPKEHPA
R
D
M
Q
D
S
F
Y
I
T
E
---------------
E
---------------
T
L
M
RTQTSPVQ
T
R
TMEKHEGKG
P
V
K
I
ICPGK
V
Y
RRDNDDATHS
H
Q
F
M
Q
I
E
G
L
V
V-----------------------------------DKNI
S
M
-----------------------------------
S
D
L
K
G
T
L
E
L
V
A
K
K
MFGQD
R
E
I
R
LRPSFFPFTEP
S
V
E
V
D
V
T
C
F
K
CGGNGCSVCKGT
G
W
I
E
I
LGAGMVHP
N
V
L
K
MA-------GF
D
P
--
K
---------
E
YQ-
G
F
AFGM
G
V
E
R
I
A
M
L
K
Y
G
I
D
D
I
R
H
F
Y
T
N
D
V
R
F
I
S
Q
F
KQA---------------------------------------------------------------------------------------------------------
30
HHSearch
85.26
79%
-94
- C1 -
2RHQ
2
SYFA_STAHJ
A:
[31-288]
-------------------------------------------------------------------------------------
Q
Q
L
A
E
E
T
I
D
V
T
L
P
S
R
Q
I
S
I
G
S
K
H
P
L
T
R
T
V
E
E
I
E
D
L
F
L
G
L
G
--------
Y
---------
E
I
V
D
G
-
Y
E
V
E
Q
D
Y
Y
N
F
E
A
L
N
L
P
K
S
H
P
A
R
D
M
Q
D
S
F
Y
I
T
D
---------------
E
---------------
I
L
M
R
T
H
T
S
P
V
Q
A
R
T
M
E
K
R
N
G
Q
G
P
V
K
I
I
C
P
G
K
V
Y
R
R
D
S
D
D
A
T
H
S
H
Q
F
T
Q
I
E
G
L
V
V
-----------------------------------
D
K
N
I
K
M
-----------------------------------
S
D
L
K
G
T
L
E
L
V
A
K
K
L
F
G
A
D
R
E
I
R
L
R
P
S
Y
F
P
F
T
E
P
S
V
E
V
D
V
S
C
F
K
C
K
G
K
G
C
N
V
C
K
H
T
G
W
I
E
I
L
G
A
G
M
V
H
P
N
V
L
E
M
A
-------
G
F
D
S
--
N
---------
E
Y
S
-
G
F
A
F
G
M
G
P
D
R
I
A
M
L
K
Y
G
I
E
D
I
R
Y
F
Y
T
N
D
V
R
F
L
E
Q
F
K
A
----------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
84.80
78%
-94
- C1 -
2RHQ
2
SYFA_STAHJ
A:
[27-287]
---------------------------------------------------------------------------------
E
K
L
N
Q
Q
L
A
E
E
T
I
D
V
T
L
P
S
R
Q
I
S
I
G
S
K
H
P
L
T
R
T
V
E
E
I
E
D
L
F
L
G
L
G
--------
Y
---------
E
I
V
D
G
-
Y
E
V
E
Q
D
Y
Y
N
F
E
A
L
N
L
P
K
S
H
P
A
R
D
M
Q
D
S
F
Y
I
T
D
---------------
E
---------------
I
L
M
R
T
H
T
S
P
V
Q
A
R
T
M
E
K
R
N
G
Q
G
P
V
K
I
I
C
P
G
K
V
Y
R
R
D
S
D
D
A
T
H
S
H
Q
F
T
Q
I
E
G
L
V
V
-----------------------------------
D
K
N
I
K
M
-----------------------------------
S
D
L
K
G
T
L
E
L
V
A
K
K
L
F
G
A
D
R
E
I
R
L
R
P
S
Y
F
P
F
T
E
P
S
V
E
V
D
V
S
C
F
K
C
K
G
K
G
C
N
V
C
K
H
T
G
W
I
E
I
L
G
A
G
M
V
H
P
N
V
L
E
M
A
-------
G
F
D
S
--
N
---------
E
Y
S
-
G
F
A
F
G
M
G
P
D
R
I
A
M
L
K
Y
G
I
E
D
I
R
Y
F
Y
T
N
D
V
R
F
L
E
Q
F
K
-----------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
83.47
78%
-93
- C1 -
2RHS
2
SYFA_STAHJ
C:
[27-287]
---------------------------------------------------------------------------------
E
K
L
N
Q
Q
L
A
E
E
T
I
D
V
T
L
P
S
R
Q
I
S
I
G
S
K
H
P
L
T
R
T
V
E
E
I
E
D
L
F
L
G
L
G
--------
Y
---------
E
I
V
D
G
-
Y
E
V
E
Q
D
Y
Y
N
F
E
A
L
N
L
P
K
S
H
P
A
R
D
M
Q
D
S
F
Y
I
T
D
---------------
E
---------------
I
L
M
R
T
H
T
S
P
V
Q
A
R
T
M
E
K
R
N
G
Q
G
P
V
K
I
I
C
P
G
K
V
Y
R
R
D
S
D
D
A
T
H
S
H
Q
F
T
Q
I
E
G
L
V
V
-----------------------------------
D
K
N
I
K
M
-----------------------------------
S
D
L
K
G
T
L
E
L
V
A
K
K
L
F
G
A
D
R
E
I
R
L
R
P
S
Y
F
P
F
T
E
P
S
V
E
V
D
V
S
C
F
K
C
K
G
K
G
C
N
V
C
K
H
T
G
W
I
E
I
L
G
A
G
M
V
H
P
N
V
L
E
M
A
-------
G
F
D
S
--
N
---------
E
Y
S
-
G
F
A
F
G
M
G
P
D
R
I
A
M
L
K
Y
G
I
E
D
I
R
Y
F
Y
T
N
D
V
R
F
L
E
Q
F
K
-----------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
81.09
78%
-92
- C1 -
2RHS
1
SYFA_STAHJ
A:
[30-287]
------------------------------------------------------------------------------------
N
Q
Q
L
A
E
E
T
I
D
V
T
L
P
S
R
Q
I
S
I
G
S
K
H
P
L
T
R
T
V
E
E
I
E
D
L
F
L
G
L
G
--------
Y
---------
E
I
V
D
G
-
Y
E
V
E
Q
D
Y
Y
N
F
E
A
L
N
L
P
K
S
H
P
A
R
D
M
Q
D
S
F
Y
I
T
D
---------------
E
---------------
I
L
M
R
T
H
T
S
P
V
Q
A
R
T
M
E
K
R
N
G
Q
G
P
V
K
I
I
C
P
G
K
V
Y
R
R
D
S
D
D
A
T
H
S
H
Q
F
T
Q
I
E
G
L
V
V
-----------------------------------
D
K
N
I
K
M
-----------------------------------
S
D
L
K
G
T
L
E
L
V
A
K
K
L
F
G
A
D
R
E
I
R
L
R
P
S
Y
F
P
F
T
E
P
S
V
E
V
D
V
S
----------------
W
I
E
I
L
G
A
G
M
V
H
P
N
V
L
E
M
A
-------
G
F
D
S
--
N
---------
E
Y
S
-
G
F
A
F
G
M
G
P
D
R
I
A
M
L
K
Y
G
I
E
D
I
R
Y
F
Y
T
N
D
V
R
F
L
E
Q
F
K
-----------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
76.08
48%
-85
- C1 -
3PCO
2
SYFA_ECOLI
C:
[5-327]
-----
A
E
L
V
A
S
A
K
A
A
I
S
Q
A
S
D
V
A
A
L
D
N
V
R
V
E
Y
L
G
K
K
G
H
L
T
L
Q
M
T
T
L
R
E
L
P
P
E
E
R
P
A
A
G
A
V
I
N
E
A
K
E
Q
V
Q
Q
A
L
N
A
R
K
A
E
L
E
S
A
A
L
N
A
R
L
A
A
E
T
I
D
V
S
L
P
G
R
R
I
E
N
G
G
L
H
P
V
T
R
T
I
D
R
I
E
S
F
F
G
E
L
G
--------
F
---------
T
V
A
T
G
-
P
E
I
E
D
D
Y
H
N
F
D
A
L
N
I
P
G
H
H
P
A
R
A
D
H
D
T
F
W
F
D
T
---------------
T
---------------
R
L
L
R
T
Q
T
S
G
V
Q
I
R
T
M
K
A
Q
Q
--
P
P
I
R
I
I
A
P
G
R
V
Y
R
N
D
Y
D
Q
-
T
H
T
P
M
F
H
Q
M
E
G
L
I
V
-----------------------------------
D
T
N
I
S
F
-----------------------------------
T
N
L
K
G
T
L
H
D
F
L
R
N
F
F
E
E
D
L
Q
I
R
F
R
P
S
Y
F
P
F
T
E
P
S
A
E
V
D
V
----
M
G
K
N
G
-------
K
W
L
E
V
L
G
C
G
M
V
H
P
N
V
L
R
N
V
-------
G
I
D
P
--
E
---------
V
Y
S
-
G
F
A
F
G
M
G
M
E
R
L
T
M
L
R
Y
G
V
T
D
L
R
S
F
F
E
N
D
L
R
F
L
K
Q
F
K
-----------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
75.35
53%
-112
- C1 -
4P71
-
SYFA_PSEAE
C:
[9-259]
----------------------------------------------------------------------------------------
A
A
E
R
I
D
V
T
L
P
G
R
G
Q
L
S
G
G
L
H
P
V
T
R
T
L
E
R
I
E
Q
C
F
S
R
I
G
--------
Y
---------
E
V
A
E
G
-
P
E
V
E
D
D
Y
H
N
F
E
A
L
N
I
P
G
H
H
P
A
R
A
M
H
D
T
F
Y
F
N
A
---------------
N
---------------
M
L
L
R
T
H
T
S
P
V
Q
V
R
T
M
E
S
Q
Q
P
--
P
I
R
I
V
C
P
G
R
V
Y
R
C
D
S
D
-
L
T
H
S
P
M
F
H
Q
V
E
G
L
L
V
-----------------------------------
D
E
G
V
S
F
-----------------------------------
A
D
L
K
G
T
I
E
E
F
L
R
A
F
F
E
K
Q
L
E
V
R
F
R
P
S
F
F
P
F
T
E
P
S
A
E
V
D
I
Q
C
------------
Q
T
G
W
L
E
V
M
G
C
G
M
V
H
P
N
V
L
R
M
S
-------
N
I
D
P
--
E
---------
K
F
Q
-
G
F
A
F
G
M
G
A
E
R
L
A
M
L
R
Y
G
V
N
D
L
R
L
F
F
D
N
D
L
R
F
L
G
Q
F
R
-----------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
74.42
53%
-113
- C1 -
4P73
1
SYFA_PSEAE
C:
[88-338]
----------------------------------------------------------------------------------------
A
A
E
R
I
D
V
T
L
P
G
R
G
Q
L
S
G
G
L
H
P
V
T
R
T
L
E
R
I
E
Q
C
F
S
R
I
G
--------
Y
---------
E
V
A
E
G
-
P
E
V
E
D
D
Y
H
N
F
E
A
L
N
I
P
G
H
H
P
A
R
A
M
H
D
T
F
Y
F
N
A
---------------
N
---------------
M
L
L
R
T
H
T
S
P
V
Q
V
R
T
M
E
S
Q
Q
P
--
P
I
R
I
V
C
P
G
R
V
Y
R
C
D
S
D
-
L
T
H
S
P
M
F
H
Q
V
E
G
L
L
V
-----------------------------------
D
E
G
V
S
F
-----------------------------------
A
D
L
K
G
T
I
E
E
F
L
R
A
F
F
E
K
Q
L
E
V
R
F
R
P
S
F
F
P
F
T
E
P
S
A
E
V
D
I
Q
C
------------
Q
T
G
W
L
E
V
M
G
C
G
M
V
H
P
N
V
L
R
M
S
-------
N
I
D
P
--
E
---------
K
F
Q
-
G
F
A
F
G
M
G
A
E
R
L
A
M
L
R
Y
G
V
N
D
L
R
L
F
F
D
N
D
L
R
F
L
G
Q
F
R
-----------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
74.14
53%
-111
- C1 -
4P75
1
SYFA_PSEAE
C:
[90-338]
------------------------------------------------------------------------------------------
E
R
I
D
V
T
L
P
G
R
G
Q
L
S
G
G
L
H
P
V
T
R
T
L
E
R
I
E
Q
C
F
S
R
I
G
--------
Y
---------
E
V
A
E
G
-
P
E
V
E
D
D
Y
H
N
F
E
A
L
N
I
P
G
H
H
P
A
R
A
M
H
D
T
F
Y
F
N
A
---------------
N
---------------
M
L
L
R
T
H
T
S
P
V
Q
V
R
T
M
E
S
Q
Q
P
--
P
I
R
I
V
C
P
G
R
V
Y
R
C
D
S
D
-
L
T
H
S
P
M
F
H
Q
V
E
G
L
L
V
-----------------------------------
D
E
G
V
S
F
-----------------------------------
A
D
L
K
G
T
I
E
E
F
L
R
A
F
F
E
K
Q
L
E
V
R
F
R
P
S
F
F
P
F
T
E
P
S
A
E
V
D
I
Q
C
--------------
G
W
L
E
V
M
G
C
G
M
V
H
P
N
V
L
R
M
S
-------
N
I
D
P
--
E
---------
K
F
Q
-
G
F
A
F
G
M
G
A
E
R
L
A
M
L
R
Y
G
V
N
D
L
R
L
F
F
D
N
D
L
R
F
L
G
Q
F
R
-----------------------------------------------------------------------------------------------------------
27
HHSearch
73.76
54%
-114
- C1 -
4P72
1
SYFA_PSEAE
C:
[90-338]
------------------------------------------------------------------------------------------
E
R
I
D
V
T
L
P
G
R
G
Q
L
S
G
G
L
H
P
V
T
R
T
L
E
R
I
E
Q
C
F
S
R
I
G
--------
Y
---------
E
V
A
E
G
-
P
E
V
E
D
D
Y
H
N
F
E
A
L
N
I
P
G
H
H
P
A
R
A
M
H
D
T
F
Y
F
N
A
---------------
N
---------------
M
L
L
R
T
H
T
S
P
V
Q
V
R
T
M
E
S
Q
Q
--
P
P
I
R
I
V
C
P
G
R
V
Y
R
C
D
S
-
D
L
T
H
S
P
M
F
H
Q
V
E
G
L
L
V
-----------------------------------
D
E
G
V
S
F
-----------------------------------
A
D
L
K
G
T
I
E
E
F
L
R
A
F
F
E
K
Q
L
E
V
R
F
R
P
S
F
F
P
F
T
E
P
S
A
E
V
D
I
Q
C
--------------
G
W
L
E
V
M
G
C
G
M
V
H
P
N
V
L
R
M
S
-------
N
I
D
P
--
E
---------
K
F
Q
-
G
F
A
F
G
M
G
A
E
R
L
A
M
L
R
Y
G
V
N
D
L
R
L
F
F
D
N
D
L
R
F
L
G
Q
F
R
-----------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
73.56
53%
-114
- C1 -
4P72
1
SYFA_PSEAE
C:
[90-338]
------------------------------------------------------------------------------------------
E
R
I
D
V
T
L
P
G
R
G
Q
L
S
G
G
L
H
P
V
T
R
T
L
E
R
I
E
Q
C
F
S
R
I
G
--------
Y
---------
E
V
A
E
G
-
P
E
V
E
D
D
Y
H
N
F
E
A
L
N
I
P
G
H
H
P
A
R
A
M
H
D
T
F
Y
F
N
A
---------------
N
---------------
M
L
L
R
T
H
T
S
P
V
Q
V
R
T
M
E
S
Q
Q
P
--
P
I
R
I
V
C
P
G
R
V
Y
R
C
D
S
D
-
L
T
H
S
P
M
F
H
Q
V
E
G
L
L
V
-----------------------------------
D
E
G
V
S
F
-----------------------------------
A
D
L
K
G
T
I
E
E
F
L
R
A
F
F
E
K
Q
L
E
V
R
F
R
P
S
F
F
P
F
T
E
P
S
A
E
V
D
I
Q
C
--------------
G
W
L
E
V
M
G
C
G
M
V
H
P
N
V
L
R
M
S
-------
N
I
D
P
--
E
---------
K
F
Q
-
G
F
A
F
G
M
G
A
E
R
L
A
M
L
R
Y
G
V
N
D
L
R
L
F
F
D
N
D
L
R
F
L
G
Q
F
R
-----------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
73.53
53%
-113
- C1 -
4P73
1
SYFA_PSEAE
D:
[87-338]
---------------------------------------------------------------------------------------
L
A
A
E
R
I
D
V
T
L
P
G
R
G
Q
L
S
G
G
L
H
P
V
T
R
T
L
E
R
I
E
Q
C
F
S
R
I
G
--------
Y
---------
E
V
A
E
G
-
P
E
V
E
D
D
Y
H
N
F
E
A
L
N
I
P
G
H
H
P
A
R
A
M
H
D
T
F
Y
F
N
A
---------------
N
---------------
M
L
L
R
T
H
T
S
P
V
Q
V
R
T
M
E
S
Q
Q
P
--
P
I
R
I
V
C
P
G
R
V
Y
R
C
D
S
D
-
L
T
H
S
P
M
F
H
Q
V
E
G
L
L
V
-----------------------------------
D
E
G
V
S
F
-----------------------------------
A
D
L
K
G
T
I
E
E
F
L
R
A
F
F
E
K
Q
L
E
V
R
F
R
P
S
F
F
P
F
T
E
P
S
A
E
V
D
I
Q
C
V
I
C
---------
Q
T
G
W
L
E
V
M
G
C
G
M
V
H
P
N
V
L
R
M
S
-------
N
I
D
P
--
E
---------
K
F
Q
-
G
F
A
F
G
M
G
A
E
R
L
A
M
L
R
Y
G
V
N
D
L
R
L
F
F
D
N
D
L
R
F
L
G
Q
F
R
-----------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
73.35
53%
-112
- C1 -
4P75
1
SYFA_PSEAE
D:
[87-338]
---------------------------------------------------------------------------------------
L
A
A
E
R
I
D
V
T
L
P
G
R
G
Q
L
S
G
G
L
H
P
V
T
R
T
L
E
R
I
E
Q
C
F
S
R
I
G
--------
Y
---------
E
V
A
E
G
-
P
E
V
E
D
D
Y
H
N
F
E
A
L
N
I
P
G
H
H
P
A
R
A
M
H
D
T
F
Y
F
N
A
---------------
N
---------------
M
L
L
R
T
H
T
S
P
V
Q
V
R
T
M
E
S
Q
Q
P
--
P
I
R
I
V
C
P
G
R
V
Y
R
C
D
S
D
-
L
T
H
S
P
M
F
H
Q
V
E
G
L
L
V
-----------------------------------
D
E
G
V
S
F
-----------------------------------
A
D
L
K
G
T
I
E
E
F
L
R
A
F
F
E
K
Q
L
E
V
R
F
R
P
S
F
F
P
F
T
E
P
S
A
E
V
D
I
Q
C
V
I
C
S
G
---------
G
W
L
E
V
M
G
C
G
M
V
H
P
N
V
L
R
M
S
-------
N
I
D
P
--
E
---------
K
F
Q
-
G
F
A
F
G
M
G
A
E
R
L
A
M
L
R
Y
G
V
N
D
L
R
L
F
F
D
N
D
L
R
F
L
G
Q
F
R
-----------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
73.10
53%
-111
- C1 -
4P74
1
SYFA_PSEAE
C:
[90-338]
------------------------------------------------------------------------------------------
E
R
I
D
V
T
L
P
G
R
G
Q
L
S
G
G
L
H
P
V
T
R
T
L
E
R
I
E
Q
C
F
S
R
I
G
--------
Y
---------
E
V
A
E
G
-
P
E
V
E
D
D
Y
H
N
F
E
A
L
N
I
P
G
H
H
P
A
R
A
M
H
D
T
F
Y
F
N
A
---------------
N
---------------
M
L
L
R
T
H
T
S
P
V
Q
V
R
T
M
E
S
Q
Q
P
--
P
I
R
I
V
C
P
G
R
V
Y
R
C
D
S
D
-
L
T
H
S
P
M
F
H
Q
V
E
G
L
L
V
-----------------------------------
D
E
G
V
S
F
-----------------------------------
A
D
L
K
G
T
I
E
E
F
L
R
A
F
F
E
K
Q
L
E
V
R
F
R
P
S
F
F
P
F
T
E
P
S
A
E
V
D
I
Q
C
--------------
G
W
L
E
V
M
G
C
G
M
V
H
P
N
V
L
R
M
S
-------
N
I
D
P
--
E
---------
K
F
Q
-
G
F
A
F
G
M
G
A
E
R
L
A
M
L
R
Y
G
V
N
D
L
R
L
F
F
D
N
D
L
R
F
L
G
Q
F
R
-----------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
72.66
53%
-112
- C1 -
4P74
1
SYFA_PSEAE
D:
[87-338]
---------------------------------------------------------------------------------------
L
A
A
E
R
I
D
V
T
L
P
G
R
G
Q
L
S
G
G
L
H
P
V
T
R
T
L
E
R
I
E
Q
C
F
S
R
I
G
--------
Y
---------
E
V
A
E
G
-
P
E
V
E
D
D
Y
H
N
F
E
A
L
N
I
P
G
H
H
P
A
R
A
M
H
D
T
F
Y
F
N
A
---------------
N
---------------
M
L
L
R
T
H
T
S
P
V
Q
V
R
T
M
E
S
Q
Q
P
--
P
I
R
I
V
C
P
G
R
V
Y
R
C
D
S
D
-
L
T
H
S
P
M
F
H
Q
V
E
G
L
L
V
-----------------------------------
D
E
G
V
S
F
-----------------------------------
A
D
L
K
G
T
I
E
E
F
L
R
A
F
F
E
K
Q
L
E
V
R
F
R
P
S
F
F
P
F
T
E
P
S
A
E
V
D
I
Q
C
V
I
C
S
G
N
--------
G
W
L
E
V
M
G
C
G
M
V
H
P
N
V
L
R
M
S
-------
N
I
D
P
--
E
---------
K
F
Q
-
G
F
A
F
G
M
G
A
E
R
L
A
M
L
R
Y
G
V
N
D
L
R
L
F
F
D
N
D
L
R
F
L
G
Q
F
R
-----------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
72.46
53%
-111
- C1 -
4P72
1
SYFA_PSEAE
D:
[87-338]
---------------------------------------------------------------------------------------
L
A
A
E
R
I
D
V
T
L
P
G
R
G
Q
L
S
G
G
L
H
P
V
T
R
T
L
E
R
I
E
Q
C
F
S
R
I
G
--------
Y
---------
E
V
A
E
G
-
P
E
V
E
D
D
Y
H
N
F
E
A
L
N
I
P
G
H
H
P
A
R
A
M
H
D
T
F
Y
F
N
A
---------------
N
---------------
M
L
L
R
T
H
T
S
P
V
Q
V
R
T
M
E
S
Q
Q
P
--
P
I
R
I
V
C
P
G
R
V
Y
R
C
D
S
D
-
L
T
H
S
P
M
F
H
Q
V
E
G
L
L
V
-----------------------------------
D
E
G
V
S
F
-----------------------------------
A
D
L
K
G
T
I
E
E
F
L
R
A
F
F
E
K
Q
L
E
V
R
F
R
P
S
F
F
P
F
T
E
P
S
A
E
V
D
I
Q
C
V
I
C
S
G
N
--------
G
W
L
E
V
M
G
C
G
M
V
H
P
N
V
L
R
M
S
-------
N
I
D
P
--
E
---------
K
F
Q
-
G
F
A
F
G
M
G
A
E
R
L
A
M
L
R
Y
G
V
N
D
L
R
L
F
F
D
N
D
L
R
F
L
G
Q
F
R
-----------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
71.04
48%
-100
- C1 -
3PCO
2
SYFA_ECOLI
A:
[86-327]
--------------------------------------------------------------------------------------
R
L
A
A
E
T
I
D
V
S
L
P
G
R
R
I
E
N
G
G
L
H
P
V
T
R
T
I
D
R
I
E
S
F
F
G
E
L
G
--------
F
---------
T
V
A
T
G
-
P
E
I
E
D
D
Y
H
N
F
D
A
L
N
I
P
G
H
H
P
A
R
A
D
H
D
T
F
W
F
D
T
---------------
T
---------------
R
L
L
R
T
Q
T
S
G
V
Q
I
R
T
M
K
A
Q
Q
--
P
P
I
R
I
I
A
P
G
R
V
Y
R
N
D
Y
D
Q
-
T
H
T
P
M
F
H
Q
M
E
G
L
I
V
-----------------------------------
D
T
N
I
S
F
-----------------------------------
T
N
L
K
G
T
L
H
D
F
L
R
N
F
F
E
E
D
L
Q
I
R
F
R
P
S
Y
F
P
F
T
E
P
S
A
E
V
D
V
----
M
G
K
N
G
-------
K
W
L
E
V
L
G
C
G
M
V
H
P
N
V
L
R
N
V
-------
G
I
D
P
--
E
---------
V
Y
S
-
G
F
A
F
G
M
G
M
E
R
L
T
M
L
R
Y
G
V
T
D
L
R
S
F
F
E
N
D
L
R
F
L
K
Q
F
K
-----------------------------------------------------------------------------------------------------------
28
HHSearch
70.61
49%
-102
- C1 -
3PCO
2
SYFA_ECOLI
A:
[86-327]
--------------------------------------------------------------------------------------
R
L
A
A
E
T
I
D
V
S
L
P
G
R
R
I
E
N
G
G
L
H
P
V
T
R
T
I
D
R
I
E
S
F
F
G
E
L
G
--------
F
---------
T
V
A
T
G
-
P
E
I
E
D
D
Y
H
N
F
D
A
L
N
I
P
G
H
H
P
A
R
A
D
H
D
T
F
W
F
D
T
---------------
T
---------------
R
L
L
R
T
Q
T
S
G
V
Q
I
R
T
M
K
A
Q
Q
--
P
P
I
R
I
I
A
P
G
R
V
Y
R
N
D
-
Y
D
Q
T
H
T
P
M
F
H
Q
M
E
G
L
I
V
-----------------------------------
D
T
N
I
S
F
-----------------------------------
T
N
L
K
G
T
L
H
D
F
L
R
N
F
F
E
E
D
L
Q
I
R
F
R
P
S
Y
F
P
F
T
E
P
S
A
E
V
D
V
M
G
-----------
K
N
G
K
W
L
E
V
L
G
C
G
M
V
H
P
N
V
L
R
N
V
-------
G
I
D
P
--
E
---------
V
Y
S
-
G
F
A
F
G
M
G
M
E
R
L
T
M
L
R
Y
G
V
T
D
L
R
S
F
F
E
N
D
L
R
F
L
K
Q
F
K
-----------------------------------------------------------------------------------------------------------
47
Fugue
66.03
42%
-5
- C1 -
1EIY
-
SYFA_THET8
A:
[6-350]
------------
L
A
A
I
Q
N
A
R
D
L
E
E
L
K
A
L
K
A
R
Y
L
G
K
K
G
L
L
T
Q
E
M
K
G
L
S
A
L
P
L
E
E
R
R
K
R
G
Q
E
L
N
A
I
K
A
A
L
E
A
A
L
E
A
R
E
K
A
L
E
E
A
A
L
K
E
A
L
E
R
E
R
V
D
V
S
L
P
G
A
S
L
F
S
G
G
L
H
P
I
T
L
M
E
R
E
L
V
E
I
F
R
A
L
G
--------
Y
---------
Q
A
V
E
G
-
P
E
V
E
S
E
F
F
N
F
D
A
L
N
I
P
E
H
H
P
A
R
D
M
W
D
T
F
W
L
T
G
---------------
E
G
F
R
L
E
G
PLG
E
E
V
E
G
R
L
L
L
R
T
H
T
S
P
M
Q
V
R
Y
M
V
A
H
--
T
P
P
F
R
I
V
V
P
G
R
V
F
R
F
E
Q
T
D
A
T
H
E
A
V
F
H
Q
L
E
G
L
V
V
-----------------------------------
G
E
G
I
A
M
-----------------------------------
A
H
L
K
G
A
I
Y
E
L
A
Q
A
L
F
G
P
D
S
K
V
R
F
Q
P
V
Y
F
P
F
V
E
P
G
A
Q
F
A
V
W
W
P
E
G
G
K
----------
W
L
E
L
G
G
A
G
M
V
H
P
K
V
F
Q
A
V
-------
D
A
Y
R
--
E
R
L
GLPPAYR
G
V
T
-
G
F
A
F
G
L
G
V
E
R
L
A
M
L
R
Y
G
I
P
D
I
R
Y
F
F
G
G
R
L
K
F
L
E
Q
F
K
G
V
L--------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
65.55
39%
-11
- C1 -
2IY5
1
SYFA_THETH
A:
[15-347]
---------------------
L
E
E
L
K
A
L
K
A
R
Y
L
G
K
K
G
L
L
T
Q
E
M
K
G
L
S
A
L
P
L
E
E
R
R
K
R
G
Q
E
L
N
A
I
K
A
A
L
E
A
A
L
E
A
R
E
K
A
L
E
E
A
A
L
K
E
A
L
E
R
E
R
V
D
V
S
L
P
G
A
S
L
F
S
G
G
L
H
P
I
T
L
M
E
R
E
L
V
E
I
F
R
A
L
G
--------
Y
---------
Q
A
V
E
G
-
P
E
V
E
S
E
F
F
N
F
D
A
L
N
I
P
E
H
H
P
A
R
D
M
W
D
T
F
W
L
T
G
---------------
E
G
F
R
L
E
G
PLG
E
E
V
E
G
R
L
L
L
R
T
H
T
S
P
M
Q
V
R
Y
M
V
A
H
--
T
P
P
F
R
I
V
V
P
G
R
V
F
R
F
E
Q
T
D
A
T
H
E
A
V
F
H
Q
L
E
G
L
V
V
-----------------------------------
G
E
G
I
A
M
-----------------------------------
A
H
L
K
G
A
I
Y
E
L
A
Q
A
L
F
G
P
D
S
K
V
R
F
Q
P
V
Y
F
P
F
V
E
P
G
A
Q
F
A
V
W
W
----------
P
E
G
G
K
W
L
E
L
G
G
A
G
M
V
H
P
K
V
F
Q
A
V
D
A
Y
R
E
R
L
G
L
P
P
AY
R
---------
G
V
T
-
G
F
A
F
G
L
G
V
E
R
L
A
M
L
R
Y
G
I
P
D
I
R
Y
F
F
G
G
R
L
K
F
L
E
Q
F
K
-----------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
65.38
39%
-3
- C1 -
1EIY
-
SYFA_THET8
A:
[6-347]
------------
L
A
A
I
Q
N
A
R
D
L
E
E
L
K
A
L
K
A
R
Y
L
G
K
K
G
L
L
T
Q
E
M
K
G
L
S
A
L
P
L
E
E
R
R
K
R
G
Q
E
L
N
A
I
K
A
A
L
E
A
A
L
E
A
R
E
K
A
L
E
E
A
A
L
K
E
A
L
E
R
E
R
V
D
V
S
L
P
G
A
S
L
F
S
G
G
L
H
P
I
T
L
M
E
R
E
L
V
E
I
F
R
A
L
G
--------
Y
---------
Q
A
V
E
G
-
P
E
V
E
S
E
F
F
N
F
D
A
L
N
I
P
E
H
H
P
A
R
D
M
W
D
T
F
W
L
T
G
---------------
E
G
F
R
L
E
G
PLG
E
E
V
E
G
R
L
L
L
R
T
H
T
S
P
M
Q
V
R
Y
M
V
A
H
--
T
P
P
F
R
I
V
V
P
G
R
V
F
R
F
E
Q
T
D
A
T
H
E
A
V
F
H
Q
L
E
G
L
V
V
-----------------------------------
G
E
G
I
A
M
-----------------------------------
A
H
L
K
G
A
I
Y
E
L
A
Q
A
L
F
G
P
D
S
K
V
R
F
Q
P
V
Y
F
P
F
V
E
P
G
A
Q
F
A
V
W
W
----------
P
E
G
G
K
W
L
E
L
G
G
A
G
M
V
H
P
K
V
F
Q
A
V
D
A
Y
R
E
R
L
G
L
P
P
AY
R
---------
G
V
T
-
G
F
A
F
G
L
G
V
E
R
L
A
M
L
R
Y
G
I
P
D
I
R
Y
F
F
G
G
R
L
K
F
L
E
Q
F
K
-----------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
63.74
39%
-24
- C1 -
3HFZ
1
SYFA_THET8
A:
[85-347]
-------------------------------------------------------------------------------------------
R
V
D
V
S
L
P
G
A
S
L
F
S
G
G
L
H
P
I
T
L
M
E
R
E
L
V
E
I
F
R
A
L
G
--------
Y
---------
Q
A
V
E
G
-
P
E
V
E
S
E
F
F
N
F
D
A
L
N
I
P
E
H
H
P
A
R
D
M
W
D
T
F
W
L
T
G
---------------
E
G
F
R
L
E
G
PLG
E
E
V
E
G
R
L
L
L
R
T
H
T
S
P
M
Q
V
R
Y
M
V
A
H
--
T
P
P
F
R
I
V
V
P
G
R
V
F
R
F
E
Q
T
D
A
T
H
E
A
V
F
H
Q
L
E
G
L
V
V
-----------------------------------
G
E
G
I
A
M
-----------------------------------
A
H
L
K
G
A
I
Y
E
L
A
Q
A
L
F
G
P
D
S
K
V
R
F
Q
P
V
Y
F
P
F
V
E
P
G
A
Q
F
A
V
W
W
----------
P
E
G
G
K
W
L
E
L
G
G
A
G
M
V
H
P
K
V
F
Q
A
V
D
A
Y
R
E
R
L
G
L
P
P
AY
R
---------
G
V
T
-
G
F
A
F
G
L
G
V
E
R
L
A
M
L
R
Y
G
I
P
D
I
R
Y
F
F
G
G
R
L
K
F
L
E
Q
F
K
-----------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
63.25
41%
-21
- C1 -
2AKW
2
SYFA_THETH
A:
[2-263]
--------------------------------------------------------------------------------------------
V
D
V
S
L
P
G
A
S
L
F
S
G
G
L
H
P
I
T
L
M
E
R
E
L
V
E
I
F
R
A
L
G
--------
Y
---------
Q
A
V
E
G
-
P
E
V
E
S
E
F
F
N
F
D
A
L
N
I
P
E
H
H
P
A
R
D
M
W
D
T
F
W
L
T
G
---------------
E
G
F
R
L
E
G
PLG
E
E
V
E
G
R
L
L
L
R
T
H
T
S
P
M
Q
V
R
Y
M
V
A
H
--
T
P
P
F
R
I
V
V
P
G
R
V
F
R
F
E
Q
T
D
A
T
H
E
A
V
F
H
Q
L
E
G
L
V
V
-----------------------------------
G
E
G
I
A
M
-----------------------------------
A
H
L
K
G
A
I
Y
E
L
A
Q
A
L
F
G
P
D
S
K
V
R
F
Q
P
V
Y
F
P
F
V
E
P
G
A
Q
F
A
V
W
W
----------
P
E
G
G
K
W
L
E
L
G
G
A
G
M
V
H
P
K
V
F
Q
A
V
D
A
Y
R
E
R
L
G
L
P
P
AY
R
---------
G
V
T
-
G
F
A
F
G
L
G
V
E
R
L
A
M
L
R
Y
G
I
P
D
I
R
Y
F
F
G
G
R
L
K
F
L
E
Q
F
K
-----------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
62.84
41%
-20
- C1 -
2AMC
2
SYFA_THETH
A:
[2-263]
--------------------------------------------------------------------------------------------
V
D
V
S
L
P
G
A
S
L
F
S
G
G
L
H
P
I
T
L
M
E
R
E
L
V
E
I
F
R
A
L
G
--------
Y
---------
Q
A
V
E
G
-
P
E
V
E
S
E
F
F
N
F
D
A
L
N
I
P
E
H
H
P
A
R
D
M
W
D
T
F
W
L
T
G
---------------
E
G
F
R
L
E
G
PLG
E
E
V
E
G
R
L
L
L
R
T
H
T
S
P
M
Q
V
R
Y
M
V
A
H
--
T
P
P
F
R
I
V
V
P
G
R
V
F
R
F
E
Q
T
D
A
T
H
E
A
V
F
H
Q
L
E
G
L
V
V
-----------------------------------
G
E
G
I
A
M
-----------------------------------
A
H
L
K
G
A
I
Y
E
L
A
Q
A
L
F
G
P
D
S
K
V
R
F
Q
P
V
Y
F
P
F
V
E
P
G
A
Q
F
A
V
W
W
----------
P
E
G
G
K
W
L
E
L
G
G
A
G
M
V
H
P
K
V
F
Q
A
V
D
A
Y
R
E
R
L
G
L
P
P
AY
R
---------
G
V
T
-
G
F
A
F
G
L
G
V
E
R
L
A
M
L
R
Y
G
I
P
D
I
R
Y
F
F
G
G
R
L
K
F
L
E
Q
F
K
-----------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
62.75
39%
-23
- C1 -
4TVA
1
SYFA_THETH
A:
[85-347]
-------------------------------------------------------------------------------------------
R
V
D
V
S
L
P
G
A
S
L
F
S
G
G
L
H
P
I
T
L
M
E
R
E
L
V
E
I
F
R
A
L
G
--------
Y
---------
Q
A
V
E
G
-
P
E
V
E
S
E
F
F
N
F
D
A
L
N
I
P
E
H
H
P
A
R
D
M
W
D
T
F
W
L
T
G
---------------
E
G
F
R
L
E
G
PLG
E
E
V
E
G
R
L
L
L
R
T
H
T
S
P
M
Q
V
R
Y
M
V
A
H
--
T
P
P
F
R
I
V
V
P
G
R
V
F
R
F
E
Q
T
D
A
T
H
E
A
V
F
H
Q
L
E
G
L
V
V
-----------------------------------
G
E
G
I
A
M
-----------------------------------
A
H
L
K
G
A
I
Y
E
L
A
Q
A
L
F
G
P
D
S
K
V
R
F
Q
P
V
Y
F
P
F
V
E
P
G
A
Q
F
A
V
W
W
----------
P
E
G
G
K
W
L
E
L
G
G
A
G
M
V
H
P
K
V
F
Q
A
V
D
A
Y
R
E
R
L
G
L
P
P
AY
R
---------
G
V
T
-
G
F
A
F
G
L
G
V
E
R
L
A
M
L
R
Y
G
I
P
D
I
R
Y
F
F
G
G
R
L
K
F
L
E
Q
F
K
-----------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
62.17
41%
-15
- C1 -
2ALY
2
SYFA_THETH
A:
[2-263]
--------------------------------------------------------------------------------------------
V
D
V
S
L
P
G
A
S
L
F
S
G
G
L
H
P
I
T
L
M
E
R
E
L
V
E
I
F
R
A
L
G
--------
Y
---------
Q
A
V
E
G
-
P
E
V
E
S
E
F
F
N
F
D
A
L
N
I
P
E
H
H
P
A
R
D
M
W
D
T
F
W
L
T
G
---------------
E
G
F
R
L
E
G
PLG
E
E
V
E
G
R
L
L
L
R
T
H
T
S
P
M
Q
V
R
Y
M
V
A
H
--
T
P
P
F
R
I
V
V
P
G
R
V
F
R
F
E
Q
T
D
A
T
H
E
A
V
F
H
Q
L
E
G
L
V
V
-----------------------------------
G
E
G
I
A
M
-----------------------------------
A
H
L
K
G
A
I
Y
E
L
A
Q
A
L
F
G
P
D
S
K
V
R
F
Q
P
V
Y
F
P
F
V
E
P
G
A
Q
F
A
V
W
W
----------
P
E
G
G
K
W
L
E
L
G
G
A
G
M
V
H
P
K
V
F
Q
A
V
D
A
Y
R
E
R
L
G
L
P
P
AY
R
---------
G
V
T
-
G
F
A
F
G
L
G
V
E
R
L
A
M
L
R
Y
G
I
P
D
I
R
Y
F
F
G
G
R
L
K
F
L
E
Q
F
K
-----------------------------------------------------------------------------------------------------------
50
Fugue
61.88
32%
6
- C1 -
3CMQ
2
SYFM_HUMAN
A:
[11-415]
------------------
P
G
S
V
V
E
L
L
G
K
S
Y
P
----------------------
Q
D
D
H
S
N
L
T
R
K
V
L
T
R
V
------------------------------
G
R
N
L
H
N
Q
Q
H
H
P
L
W
L
I
K
E
R
V
K
E
H
F
Y
K
Q
Y
--------
V
G
R
F
GT
P
L
F
S
V
Y
D
N
L
-
S
P
V
V
T
T
W
Q
N
F
D
S
L
L
I
P
A
D
H
P
S
R
K
K
G
D
N
Y
Y
L
N
R
---------------
T
---------------
H
M
L
R
A
H
T
S
A
H
Q
W
D
L
L
H
A
----
G
L
D
A
F
L
V
V
G
D
V
Y
R
R
D
Q
I
D
S
Q
H
Y
P
I
F
H
Q
L
E
A
V
R
L
-----------------------------------
F
S
K
H
E
L
F
AGIKDGESLQL
F
E
Q
S
S
R
S
AHKQETHT
M
E
A
V
K
L
V
E
F
D
L
K
Q
T
L
T
R
L
M
A
H
L
F
G
D
E
L
E
I
R
W
V
D
C
Y
F
P
F
T
H
P
S
F
E
M
E
I
N
F
------------
H
G
E
W
L
E
V
L
G
C
G
V
M
E
Q
Q
L
V
N
S
A
-------
G
--
A
--
Q
---------
D
R
I
-
G
W
A
F
G
L
G
L
E
R
L
A
M
I
L
Y
D
I
P
D
I
R
L
F
W
C
E
D
E
R
F
L
K
Q
F
C
V
S
NINQKVK
F
Q
P
L
S
K
Y
P
A
V
I
N
D
I
S
F
W
L
P
SENYA
E
N
D
F
Y
D
L
V
R
T
I
GGDLVEKVDLI
D
K
F
V
H
PKTH
K
T
S
H
C
Y
R
I
T
Y
R
H
ME
R
T
L
S
Q
R
E
V
R
H
I
H
Q
A
L
Q
E
A
A
V
Q
LLGVEGRF
12
PsiBlast_PDB
61.86
39%
-14
- C1 -
1B70
2
SYFA_THETH
A:
[86-347]
--------------------------------------------------------------------------------------------
V
D
V
S
L
P
G
A
S
L
F
S
G
G
L
H
P
I
T
L
M
E
R
E
L
V
E
I
F
R
A
L
G
--------
Y
---------
Q
A
V
E
G
-
P
E
V
E
S
E
F
F
N
F
D
A
L
N
I
P
E
H
H
P
A
R
D
M
W
D
T
F
W
L
T
G
---------------
E
G
F
R
L
E
G
PLG
E
E
V
E
G
R
L
L
L
R
T
H
T
S
P
M
Q
V
R
Y
M
V
A
H
--
T
P
P
F
R
I
V
V
P
G
R
V
F
R
F
E
Q
T
D
A
T
H
E
A
V
F
H
Q
L
E
G
L
V
V
-----------------------------------
G
E
G
I
A
M
-----------------------------------
A
H
L
K
G
A
I
Y
E
L
A
Q
A
L
F
G
P
D
S
K
V
R
F
Q
P
V
Y
F
P
F
V
E
P
G
A
Q
F
A
V
W
W
----------
P
E
G
G
K
W
L
E
L
G
G
A
G
M
V
H
P
K
V
F
Q
A
V
D
A
Y
R
E
R
L
G
L
P
P
AY
R
---------
G
V
T
-
G
F
A
F
G
L
G
V
E
R
L
A
M
L
R
Y
G
I
P
D
I
R
Y
F
F
G
G
R
L
K
F
L
E
Q
F
K
-----------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
61.55
39%
-19
- C1 -
1JJC
2
SYFA_THET8
A:
[85-347]
-------------------------------------------------------------------------------------------
R
V
D
V
S
L
P
G
A
S
L
F
S
G
G
L
H
P
I
T
L
M
E
R
E
L
V
E
I
F
R
A
L
G
--------
Y
---------
Q
A
V
E
G
-
P
E
V
E
S
E
F
F
N
F
D
A
L
N
I
P
E
H
H
P
A
R
D
M
W
D
T
F
W
L
T
G
---------------
E
G
F
R
L
E
G
PLGE
E
V
E
G
R
L
L
L
R
T
H
T
S
P
M
Q
V
R
Y
M
V
A
H
--
T
P
P
F
R
I
V
V
P
G
R
V
F
R
F
E
Q
T
D
A
T
H
E
A
V
F
H
Q
L
E
G
L
V
V
-----------------------------------
G
E
G
I
A
M
-----------------------------------
A
H
L
K
G
A
I
Y
E
L
A
Q
A
L
F
G
P
D
S
K
V
R
F
Q
P
V
Y
F
P
F
V
E
P
G
A
Q
F
A
V
W
W
----------
P
E
G
G
K
W
L
E
L
G
G
A
G
M
V
H
P
K
V
F
Q
A
V
D
A
Y
R
E
R
L
G
L
P
P
AY
R
---------
G
V
T
-
G
F
A
F
G
L
G
V
E
R
L
A
M
L
R
Y
G
I
P
D
I
R
Y
F
F
G
G
R
L
K
F
L
E
Q
F
K
-----------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
60.64
39%
-17
- C1 -
3TEH
1
SYFA_THETH
A:
[85-347]
-------------------------------------------------------------------------------------------
R
V
D
V
S
L
P
G
A
S
L
F
S
G
G
L
H
P
I
T
L
M
E
R
E
L
V
E
I
F
R
A
L
G
--------
Y
---------
Q
A
V
E
G
-
P
E
V
E
S
E
F
F
N
F
D
A
L
N
I
P
E
H
H
P
A
R
D
M
W
D
T
F
W
L
T
G
---------------
E
GFRLEGPLG
E
E
V
E
G
R
L
L
L
R
T
H
T
S
P
M
Q
V
R
Y
M
V
A
H
--
T
P
P
F
R
I
V
V
P
G
R
V
F
R
F
E
Q
T
D
A
T
H
E
A
V
F
H
Q
L
E
G
L
V
V
-----------------------------------
G
E
G
I
A
M
-----------------------------------
A
H
L
K
G
A
I
Y
E
L
A
Q
A
L
F
G
P
D
S
K
V
R
F
Q
P
V
Y
F
P
F
V
E
P
G
A
Q
F
A
V
W
W
----------
P
E
G
G
K
W
L
E
L
G
G
A
G
M
V
H
P
K
V
F
Q
A
V
D
A
Y
R
E
R
L
G
L
P
P
AY
R
---------
G
V
T
-
G
F
A
F
G
L
G
V
E
R
L
A
M
L
R
Y
G
I
P
D
I
R
Y
F
F
G
G
R
L
K
F
L
E
Q
F
K
-----------------------------------------------------------------------------------------------------------
29
HHSearch
60.25
43%
-13
- C1 -
1B7Y
2
SYFA_THETH
A:
[86-348]
--------------------------------------------------------------------------------------------
V
D
V
S
L
P
G
A
S
L
F
S
G
G
L
H
P
I
T
L
M
E
R
E
L
V
E
I
F
R
A
L
G
--------
Y
---------
Q
A
V
E
G
-
P
E
V
E
S
E
F
F
N
F
D
A
L
N
I
P
E
H
H
P
A
R
D
M
W
D
T
F
W
L
T
G
E
G
F
R
L
E
G
PLG
E
E
V
E
G
R
---------------
L
L
L
R
T
H
T
S
P
M
Q
V
R
Y
M
V
A
H
--
T
P
P
F
R
I
V
V
P
G
R
V
F
R
F
E
Q
T
D
A
T
H
E
A
V
F
H
Q
L
E
G
L
V
V
-----------------------------------
G
E
G
I
A
M
-----------------------------------
A
H
L
K
G
A
I
Y
E
L
A
Q
A
L
F
G
P
D
S
K
V
R
F
Q
P
V
Y
F
P
F
V
E
P
G
A
Q
F
A
V
W
W
P
----------
E
G
G
K
W
L
E
L
G
G
A
G
M
V
H
P
K
V
F
Q
A
V
D
A
Y
R
E
R
L
G
L
P
P
AY
R
---------
G
V
T
-
G
F
A
F
G
L
G
V
E
R
L
A
M
L
R
Y
G
I
P
D
I
R
Y
F
F
G
G
R
L
K
F
L
E
Q
F
K
G
----------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
59.21
39%
-14
- C1 -
1B7Y
2
SYFA_THETH
A:
[86-347]
--------------------------------------------------------------------------------------------
V
D
V
S
L
P
G
A
S
L
F
S
G
G
L
H
P
I
T
L
M
E
R
E
L
V
E
I
F
R
A
L
G
--------
Y
---------
Q
A
V
E
G
-
P
E
V
E
S
E
F
F
N
F
D
A
L
N
I
P
E
H
H
P
A
R
D
M
W
D
T
F
W
L
T
G
---------------
E
G
F
R
L
E
G
PLG
E
E
V
E
G
R
L
L
L
R
T
H
T
S
P
M
Q
V
R
Y
M
V
A
H
--
T
P
P
F
R
I
V
V
P
G
R
V
F
R
F
E
Q
T
D
A
T
H
E
A
V
F
H
Q
L
E
G
L
V
V
-----------------------------------
G
E
G
I
A
M
-----------------------------------
A
H
L
K
G
A
I
Y
E
L
A
Q
A
L
F
G
P
D
S
K
V
R
F
Q
P
V
Y
F
P
F
V
E
P
G
A
Q
F
A
V
W
W
----------
P
E
G
G
K
W
L
E
L
G
G
A
G
M
V
H
P
K
V
F
Q
A
V
D
A
Y
R
E
R
L
G
L
P
P
AY
R
---------
G
V
T
-
G
F
A
F
G
L
G
V
E
R
L
A
M
L
R
Y
G
I
P
D
I
R
Y
F
F
G
G
R
L
K
F
L
E
Q
F
K
-----------------------------------------------------------------------------------------------------------
32
HHSearch
49.20
35%
12
- C1 -
3CMQ
2
SYFM_HUMAN
A:
[41-307]
----------------------------------------------------------------------------------------------------
N
L
H
N
Q
Q
H
H
P
L
W
L
I
K
E
R
V
K
E
H
F
Y
K
Q
Y
V
G
R
F
GT
P
L
F
---------
S
V
Y
D
N
L
S
P
V
V
T
T
W
Q
N
F
D
S
L
L
I
P
A
D
H
P
S
R
K
K
G
D
N
Y
Y
L
N
R
---------------
T
---------------
H
M
L
R
A
H
T
S
A
H
Q
W
D
L
L
H
A
----
G
L
D
A
F
L
V
V
G
D
V
Y
R
R
D
Q
I
D
S
Q
H
Y
P
I
F
H
Q
L
E
A
V
R
L
F
S
K
H
E
L
F
AGIKDGESLQL
F
E
Q
S
S
R
S
AHKQETHT
M
E
A
V
K
L
V
E
-----------------------------------
F
D
L
K
Q
T
L
T
R
L
M
A
H
L
F
G
D
E
L
E
I
R
W
V
D
C
Y
F
P
F
T
H
P
S
F
E
M
E
I
N
F
------------
H
G
E
W
L
E
V
L
G
C
G
V
M
E
Q
Q
L
V
N
S
A
-------
G
A
Q
--------------
D
R
I
G
W
A
F
G
L
G
L
E
R
L
A
M
I
L
Y
D
I
P
D
I
R
L
F
W
C
E
D
E
R
F
L
K
Q
F
------------------------------------------------------------------------------------------------------------