@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu29190: (2016-07-17 )
MKRIGVLTSGGDSPGMNAAVRAVVRKAIYHDVEVYGIYNGYAGLISGKIEKLELGSVGDIIHRGGTKLYTARCPEFKTVEGREKGIANLKKLGIEGLVVIGGDGSYMGAKKLTEHGFPCVGVPGTIDNDIPGTDFTIGFDTALNTVIDAIDKIRDTATSHERTYVIEVMGRHAGDIALWAGLAGGAESILIPEADYDMHEIIARLKRGHERGKKHSIIIVAEGVGSGVEFGKRIEEETNLETRVSVLGHIQRGGSPSAADRVLASRLGAYAVELLLEGKGGRCVGIQNNKLVDHDIIEILETKHTVEQNMYQLSKELSI
Atome Classification :
(27 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.....-..210.......220.......230.......240.......250.......260.......270.......280.......290.......300-.......310.......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
K
R
I
G
V
L
TSGGDSP
G
M
N
A
A
V
R
A
V
V
R
K
A
I
YHD
V
E
V
Y
G
I
YNGY
A
G
L
ISG
K
I
E
K
L
ELGS
V
G
D
I
I
HRGG
T
K
L
Y
T
ARCPEFKTVE
G
R
E
K
G
I
A
N
L
K
K
LGI
E
G
L
V
V
IGGDGSYM
G
A
K
K
L
T
EHGFPCVGVPGTIDNDIPGT
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
TATSHE
R
T
Y
V
I
E
V
M
G
RHAG
D
I
A
L
W
A
GLAGGA
E
S
I
L
IPEADY
D
M
H
E
I
I
A
R
L
K
R
-
G
H
ERGK
K
H
S
I
I
I
V
AEGVG
S
G
V
E
F
G
K
R
I
E
E
ET
N
L
E
T
R
V
S
V
L
G
H
I
QRGGS
P
S
A
A
D
R
V
L
A
S
R
L
G
A
Y
A
V
E
L
LLEGKG
G
R
C
V
GIQNNKLV
D
H
D
I
I
E
I
L
E
T-K
H
T
V
E
Q
N
M
Y
Q
L
S
K
E
LSI
1
PsiBlast_PDB
94.28
100%
-111
- C3 -
4A3S
-
PFKA_BACSU
A:
[1-319]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
V
R
A
V
V
R
K
A
I
Y
H
D
V
E
V
Y
G
I
Y
N
G
Y
A
G
L
I
S
G
K
I
E
K
L
E
L
G
S
V
G
D
I
I
H
R
G
G
T
K
L
Y
T
A
R
C
P
E
F
K
T
V
E
G
R
E
K
G
I
A
N
L
K
K
L
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
M
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
A
G
L
A
G
G
A
E
S
I
L
I
P
E
A
D
Y
D
M
H
E
I
I
A
R
L
K
R
-
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
E
F
G
K
R
I
E
E
E
T
N
L
E
T
R
V
S
V
L
G
H
I
Q
R
G
G
S
P
S
A
A
D
R
V
L
A
S
R
L
G
A
Y
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
K
L
V
D
H
D
I
I
E
I
L
E
T
-
K
H
T
V
E
Q
N
M
Y
Q
L
S
K
E
L
S
I
5
PsiBlast_PDB
92.80
85%
-116
- C3 -
4PFK
4
PFKA_GEOSE
A:
[1-319]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
Q
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
-
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
Q
E
A
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
A
E
A
L
A
N
-
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
23
PsiBlast_CBE
92.10
86%
-108
- C3 -
6PFK
2
PFKA_GEOSE
B:
[1-319]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
-
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
Q
E
A
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
A
E
A
L
A
N
-
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
4
PsiBlast_PDB
91.87
85%
-114
- C3 -
3PFK
2
PFKA_GEOSE
A:
[1-319]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
Q
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
-
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
Q
E
A
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
A
E
A
L
A
N
-
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
2
PsiBlast_PDB
91.55
86%
-110
- C3 -
6PFK
2
PFKA_GEOSE
A:
[1-319]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
-
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
Q
E
A
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
A
E
A
L
A
N
-
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
26
PsiBlast_CBE
91.26
86%
-116
- C3 -
3U39
2
PFKA_GEOSE
B:
[1-318]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
-
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
Q
E
A
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
A
E
A
L
A
N
-
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
-
29
PsiBlast_CBE
91.19
85%
-112
- C3 -
4I4I
2
PFKA_GEOSE
B:
[1-319]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
A
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
-
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
Q
E
A
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
A
E
A
L
A
N
-
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
27
PsiBlast_CBE
91.06
85%
-115
- C3 -
4I4I
2
PFKA_GEOSE
D:
[1-319]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
A
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
-
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
Q
E
A
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
A
E
A
L
A
N
-
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
22
PsiBlast_CBE
90.97
86%
-112
- C3 -
6PFK
2
PFKA_GEOSE
C:
[1-319]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
-
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
Q
E
A
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
A
E
A
L
A
N
-
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
25
PsiBlast_CBE
90.83
86%
-112
- C3 -
3U39
3
PFKA_GEOSE
C:
[1-319]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
-
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
Q
E
A
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
A
E
A
L
A
N
-
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
9
PsiBlast_PDB
90.71
85%
-113
- C3 -
1MTO
2
PFKA_GEOSE
A:
[1-319]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
W
V
I
E
V
M
G
R
H
A
G
D
I
A
L
Y
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
-
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
Q
E
A
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
A
E
A
L
A
N
-
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
6
PsiBlast_PDB
90.63
85%
-107
- C3 -
4I4I
2
PFKA_GEOSE
A:
[1-319]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
A
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
-
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
Q
E
A
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
A
E
A
L
A
N
-
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
21
PsiBlast_CBE
90.55
86%
-111
- C3 -
6PFK
2
PFKA_GEOSE
D:
[1-319]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
-
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
Q
E
A
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
A
E
A
L
A
N
-
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
24
PsiBlast_CBE
90.36
86%
-110
- C3 -
3U39
2
PFKA_GEOSE
D:
[1-319]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
-
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
Q
E
A
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
A
E
A
L
A
N
-
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
36
PsiBlast_CBE
90.18
85%
-107
- C3 -
1MTO
2
PFKA_GEOSE
E:
[1-319]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
W
V
I
E
V
M
G
R
H
A
G
D
I
A
L
Y
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
-
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
Q
E
A
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
A
E
A
L
A
N
-
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
30
PsiBlast_CBE
90.15
85%
-111
- C3 -
4I7E
2
PFKA_GEOSE
D:
[1-319]
M
K
R
I
G
V
L
T
S
G
G
A
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
-
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
Q
E
A
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
A
E
A
L
A
N
-
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
3
PsiBlast_PDB
90.07
86%
-112
- C3 -
3U39
1
PFKA_GEOSE
A:
[1-319]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
-
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
Q
E
A
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
A
E
A
L
A
N
-
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
8
PsiBlast_PDB
90.00
85%
-111
- C3 -
4I7E
2
PFKA_GEOSE
A:
[1-319]
M
K
R
I
G
V
L
T
S
G
G
A
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
-
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
Q
E
A
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
A
E
A
L
A
N
-
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
39
PsiBlast_CBE
89.87
85%
-112
- C3 -
1MTO
3
PFKA_GEOSE
B:
[1-319]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
W
V
I
E
V
M
G
R
H
A
G
D
I
A
L
Y
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
-
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
Q
E
A
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
A
E
A
L
A
N
-
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
37
PsiBlast_CBE
89.48
85%
-112
- C3 -
1MTO
2
PFKA_GEOSE
D:
[1-319]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
W
V
I
E
V
M
G
R
H
A
G
D
I
A
L
Y
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
-
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
Q
E
A
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
A
E
A
L
A
N
-
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
28
PsiBlast_CBE
89.45
85%
-112
- C3 -
4I4I
2
PFKA_GEOSE
C:
[1-319]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
A
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
-
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
Q
E
A
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
A
E
A
L
A
N
-
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
32
PsiBlast_CBE
89.43
85%
-107
- C3 -
4I7E
2
PFKA_GEOSE
B:
[1-319]
M
K
R
I
G
V
L
T
S
G
G
A
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
-
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
Q
E
A
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
A
E
A
L
A
N
-
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
31
PsiBlast_CBE
88.87
85%
-110
- C3 -
4I7E
2
PFKA_GEOSE
C:
[1-319]
M
K
R
I
G
V
L
T
S
G
G
A
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
-
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
Q
E
A
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
A
E
A
L
A
N
-
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
10
PsiBlast_PDB
83.19
56%
-119
- C3 -
1PFK
6
PFKA_ECOLI
A:
[2-319]
I
K
K
I
G
V
L
T
S
G
G
D
A
P
G
M
N
A
A
I
R
G
V
V
R
S
A
L
T
E
G
L
E
V
M
G
I
Y
D
G
Y
L
G
L
Y
E
D
R
M
V
Q
L
D
R
Y
S
V
S
D
M
I
N
R
G
G
T
F
L
G
S
A
R
F
P
E
F
R
D
E
N
I
R
A
V
A
I
E
N
L
K
K
R
G
I
D
A
L
V
V
I
G
G
D
G
S
Y
M
G
A
M
R
L
T
E
M
G
F
P
C
I
G
L
P
G
T
I
D
N
D
I
K
G
T
D
Y
T
I
G
F
F
T
A
L
S
T
V
V
E
A
I
D
R
L
R
D
T
S
S
S
H
Q
R
I
S
V
V
E
V
M
G
R
Y
C
G
D
L
T
L
A
A
A
I
A
G
G
C
E
F
V
V
V
P
E
V
E
F
S
R
E
D
L
V
N
E
I
K
A
-
G
I
A
K
G
K
K
H
A
I
V
A
I
T
E
H
M
C
D
V
D
E
L
A
H
F
I
E
K
E
T
G
R
E
T
R
A
T
V
L
G
H
I
Q
R
G
G
S
P
V
P
Y
D
R
I
L
A
S
R
M
G
A
Y
A
I
D
L
L
L
A
G
Y
G
G
R
C
V
G
I
Q
N
E
Q
L
V
H
H
D
I
I
D
A
I
E
N
M
K
R
P
F
K
G
D
W
L
D
C
A
K
K
L
--
40
PsiBlast_CBE
83.03
56%
-121
- C3 -
1PFK
6
PFKA_ECOLI
B:
[2-319]
I
K
K
I
G
V
L
T
S
G
G
D
A
P
G
M
N
A
A
I
R
G
V
V
R
S
A
L
T
E
G
L
E
V
M
G
I
Y
D
G
Y
L
G
L
Y
E
D
R
M
V
Q
L
D
R
Y
S
V
S
D
M
I
N
R
G
G
T
F
L
G
S
A
R
F
P
E
F
R
D
E
N
I
R
A
V
A
I
E
N
L
K
K
R
G
I
D
A
L
V
V
I
G
G
D
G
S
Y
M
G
A
M
R
L
T
E
M
G
F
P
C
I
G
L
P
G
T
I
D
N
D
I
K
G
T
D
Y
T
I
G
F
F
T
A
L
S
T
V
V
E
A
I
D
R
L
R
D
T
S
S
S
H
Q
R
I
S
V
V
E
V
M
G
R
Y
C
G
D
L
T
L
A
A
A
I
A
G
G
C
E
F
V
V
V
P
E
V
E
F
S
R
E
D
L
V
N
E
I
K
A
-
G
I
A
K
G
K
K
H
A
I
V
A
I
T
E
H
M
C
D
V
D
E
L
A
H
F
I
E
K
E
T
G
R
E
T
R
A
T
V
L
G
H
I
Q
R
G
G
S
P
V
P
Y
D
R
I
L
A
S
R
M
G
A
Y
A
I
D
L
L
L
A
G
Y
G
G
R
C
V
G
I
Q
N
E
Q
L
V
H
H
D
I
I
D
A
I
E
N
M
K
R
P
F
K
G
D
W
L
D
C
A
K
K
L
--
83
HHSearch
78.94
85%
-81
- C3 -
4I7E
2
PFKA_GEOSE
A:
[1-319]
M
K
R
I
G
V
L
T
S
G
G
A
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
G
H
E
-
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
Q
E
A
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
A
E
A
L
A
N
-
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
81
HHSearch
72.87
56%
-89
* C3 *
1PFK
6
PFKA_ECOLI
A:
[2-320]
I
K
K
I
G
V
L
T
S
G
G
D
A
P
G
M
N
A
A
I
R
G
V
V
R
S
A
L
T
E
G
L
E
V
M
G
I
Y
D
G
Y
L
G
L
Y
E
D
R
M
V
Q
L
D
R
Y
S
V
S
D
M
I
N
R
G
G
T
F
L
G
S
A
R
F
P
E
F
R
D
E
N
I
R
A
V
A
I
E
N
L
K
K
R
G
I
D
A
L
V
V
I
G
G
D
G
S
Y
M
G
A
M
R
L
T
E
M
G
F
P
C
I
G
L
P
G
T
I
D
N
D
I
K
G
T
D
Y
T
I
G
F
F
T
A
L
S
T
V
V
E
A
I
D
R
L
R
D
T
S
S
S
H
Q
R
I
S
V
V
E
V
M
G
R
Y
C
G
D
L
T
L
A
A
A
I
A
G
G
C
E
F
V
V
V
P
E
V
E
F
S
R
E
D
L
V
N
E
I
K
A
G
I
A
-
K
G
K
K
H
A
I
V
A
I
T
E
H
M
C
D
V
D
E
L
A
H
F
I
E
K
E
T
G
R
E
T
R
A
T
V
L
G
H
I
Q
R
G
G
S
P
V
P
Y
D
R
I
L
A
S
R
M
G
A
Y
A
I
D
L
L
L
A
G
Y
G
G
R
C
V
G
I
Q
N
E
Q
L
V
H
H
D
I
I
D
A
I
E
N
M
K
R
P
F
K
G
D
W
L
D
C
A
K
K
L
Y
-