@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu30410: (2016-07-20 )
MRFKDQVHFIRRNMKKNRLRVFMTILATTMACAFLVVLSSVGFGIQKTITDMTMSQQIVTKVSVMGKEGDKPIKKADLEKYDHVRSVVERTQVYEPNKATLGNRTNESSNLIFTNMNDELKANMELEKGRVAKSENEIVVGYDFAKRLLTKKESEEYNKKIEEAKGNPEDIKEPKGYTKDILNKTIELSVSKTDSKTGDVTKTKTYDFKIVGITKKPSQDWMEDSNIFISDQFKKDFSEFLDFKGGNVETNIGVFADKFENVEQLTNDLTDDGYYVTSVTTELEGANTFFMVFKIGLIFVGCIAVIISAIGIFNTMTMAVTERTQEIGIMKAIGASPSIIRRMFLMESAYIGILGCVIGIIISYGVSYLVNLAVPMILAATSGGDAGDLNYTFSYIPASLVIIAVVICGGVAVISGMNPARKATKTNVLTALRREL
Atome Classification :
(20 SA)
-----------....-....------------------.10........20-........30........40........50........60........70........80...--.....90........100.......110.....-..120.......130-.-----.-----...---...140...-.....150.......160........170.......180----------........190.......200.......-210......-.220.......230....-..-...240--....-...250.......260.......270.......280........290.....-------..300.......310.......320.......330.......340..--.....350.......360.......370...-------....380..-----.....390...-----------....400...-----.-------...410.......-420.......430....-----------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------MRF
K
-
D
Q
V
H
------------------
F
I
R
R
NM
K
K
N
R
L
R
V
-
F
M
T
I
L
A
T
T
M
A
C
A
F
L
V
V
L
S
S
VGF
G
I
Q
K
T
I
T
D
M
T
M
S
Q
Q
I
V
T
K
V
S
VMGKEGDKP
I
K
K
A
D
L
E
K
Y
D
H
V
--
R
S
V
V
E
R
T
QVYEPNKATLGNRTNESS
N
L
I
F
TNMN-D
E
L
K
AN
M
E
LEKGR-V-A-----K-----SEN---
E
I
V
V
G
-
Y
D
F
-
A
K
R
L
L
T
K
K
E
S
E
E
Y
N
K
K
-
I
E
EAKG
N
P
E
DIKEPKG
Y
T
K
D
I
-----------
L
NK
T
I
E
L
S
V
SKTDSKTGD
V
T
K
T
K
T
Y
D
F
K
-
I
V
G
I
TKKP
S
-
Q
D
WMEDS
N
I
F
I
S
--
D
Q
F
K
-
K
D
-
F
S
E
F
L
D--FKGG-N
V
E
TNIG
V
F
A
D
K
F
E
N
V
E
Q
L
T
NDLTDD
G
Y
Y
V
T
S
V
T
-
T
ELEGA
N
T
F
F
M
V
F
K
I
G
L
-------
I
F
V
G
C
I
A
V
I
I
S
A
I
G
I
F
N
T
M
T
M
A
V
T
E
R
T
Q
EI
G
I
M
K
AIGA
S
P
S
I
I
R
R
M
F
--
L
M
E
S
A
Y
I
G
I
L
G
C
V
I
G
I
I
I
S
Y
G
V
S
Y
L
V
N
LA
V
P
-------
M
I
L
A
ATSGG-----DAGD
L
N
Y
T
F
SY-----------I
P
A
S
L
V
I
I
A
V
-----
V
-------
I
CG
G
V
A
V
ISGMNP-ARK
A
T
K
T
N
V
L
T
A
L
R
REL-----------
22
Fugue
68.30
18%
-3
- C3 -
3W36
1
?
A:
[58-527]
-----------
I
E
F
D
L
D
K
D
N
------------------
Y
I
K
W
A
Q
P
-------------
T
D
E
N
A
G
Q
S
P
T
L
A
I
L
G
P
------
M
D
V
T
V
F
L
W
I
N
R
V
V
W
L
A
A
F
D
A
L
A
P
Y
H
E
T
A
V
G
V
Y
S
Q
I
PR
R
P
S
S
E
S
A
T
N
R
N
L
N
I
A
A
L
H
A
Q
H
G
V
W
K
R
V
L
P
Q
Q
V
D
-
Q
L
R
E
L
M
T
A
L
G
L
D
P
-
S
-
D
-----
E
-----
T
E
N
LSS
P
V
G
I
G
-
N
V
A
-
A
K
N
A
F
N
A
L
K
N
D
G
M
N
F
L
G
Y
E
G
R
K
Y
N
P
R
P
W
A
D
Y
T
G
Y
E
P
V
N
TAFKVNNPS
R
W
Q
P
Q
L
Q
A
H
N
A
R
R
A
G
G
G
P
G
D
L
G
I
Y
V
T
Q
H
F
V
-
T
P
Q
T
A
R
T
K
A
-
H
I
F
R
D
P
S
R
F
R
I
P
--
R
--------
P
E
F
S
D
--
H
-------
T
N
T
R
A
Y
K
R
S
V
D
E
I
I
D
A
S
A
N
L
N
D
E
R
K
A
L
A
E
I
M
E
N
K
L
W
G
I
G
H
S
S
I
V
I
A
N
K
Y
D
QNNEMG
V
H
G
W
C
H
W
M
L
A
H
V
L
A
T
F
E
P
L
I
A
A
W
H
H
K
T
R
F
D
A
V
-----
R
P
V
T
A
I
R
H
V
Y
GN
R
K
I
R
A
W
G
G
V
G
M
G
T
V
D
I
R
A
S
E
W
S
S
Y
L
P
V
G
D
H
P
EYPS
G
S
T
S
L
C
S
A
T
S
Q
A
A
R
R
Y
F
D
S
D
E
L
D
W
T
I
N
Y
P
A
GSTVVEPGI
T
P
G
K
D
L
S
I
H
I
-----
P
T
W
T
D
F
T
R
T
C
A
T
S
R
V
W
G
G
V
H
F
-
Q
T
T
V
D
R
T
I
D
F
G
E
Q
F
G
D
L
A
H
E
F
V
Q
R
H
V
K
G
25
Fugue
66.53
18%
12
- C2 -
4WW4
1
?
A:
[3-458]
QISE
V
R
G
N
T
RD
H
R
T
A
-
A
H
T
H
IKGLGLNSSGIAEKQAAG
F
V
G
Q
C
A
A
R
E
A
C
G
V
-
V
V
D
L
I
K
A
H
K
M
A
G
R
G
V
L
L
A
G
-
G
P
G
T
G
K
T
A
L
A
L
A
I
S
Q
E
L
G
T
K
I
P
------
F
C
P
I
T
G
S
E
I
----
Y
S
--
T
E
V
K
K
T
E
V
L
M
E
N
F
R
R
A
I
G
L
R
V
R
E
T
K
D
-
V
Y
E
G
E
V
-
S
T
L
L
I
G
L
K
S
A
R
G
Q
-
K
-
L
-----
D
-----
Q
K
E
---
R
V
Q
V
G
D
V
I
Y
-
I
E
T
N
T
G
A
C
R
S
D
A
Y
A
T
E
-
F
D
--
L
E
A
E
E
Y
V
P
I
P
K
G
-----------------------
E
V
H
K
K
K
E
I
V
Q
D
V
T
L
H
D
L
D
V
A
N
-
A
R
P
D
I
I
S
M
M
-
G
Q
L
M
K
P
K
M
T
E
I
T
--
D
K
L
R
-
M
E
-
I
N
K
V
V
Q
K
Y
I
N
Q
G
-
V
A
E
L
I
P
G
V
L
F
--
I
D
E
A
H
M
L
------
D
I
E
C
F
T
Y
L
N
-
K
A
L
E
S
P
I
A
P
I
V
V
L
A
S
N
-----------
R
G
I
A
T
I
R
G
A
D
D
L
-
K
A
A
H
G
I
P
P
D
F
L
Q
R
L
L
I
I
P
T
H
P
Y
E
P
D
E
I
R
R
I
V
--
R
I
R
A
Q
T
E
G
-----------------
V
Q
L
T
D
A
-------
A
V
D
R
V
A
E
H
G
-----
V
R
I
S
L
R
Y
C
L
Q
L
-----------
L
A
P
A
S
I
L
A
R
V
N
GRTQ
V
-------
D
V
Q
D
I
A
E
A
E
E
L
F
L
D
A
R
R
S
A
N
I
L
T
S
T
G
G
L
H
-------------
13
HHSearch
37.31
17%
-188
- C4 -
1IXS
-
A:
[21-38]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
M
A
L
A
A
L
G
F
K
E
A
Q
A
R
A
V
V
---------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
34.93
17%
100
- C5 -
5F9Q
-
?
A:
[76-197]
--------------------------------------------------------------------------------------------------------------------------------------------
D
I
T
L
N
G
I
N
S
G
Y
M
D
V
K
-
K
L
D
V
Q
D
G
R
T
F
-
T
-----
D
N
D
F
L
S
G
K
R
---
A
G
I
I
S
-
K
K
M
-
A
E
K
L
F
G
K
----------------------------
T
S
P
-----------
L
G
K
I
V
W
A
G
--------------
G
-
Q
P
V
E
-
V
I
G
V
L
K
E
-------
G
L
S
E
M
Y
V
P
--
F
N
M
L
-
K
T
-
S
-------
F
G
T
--
N
D
Y
S
N
V
S
V
Q
T
E
S
A
D
Q
I
K
S
T
G
K
E
A
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
34.68
0%
-144
- C1 -
2ROD
-
APR_MOUSE
B:
[29-37]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
-----------
I
G
D
K
V
Y
C
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
34.66
28%
26
- C4 -
3G68
-
?
A:
[192-311]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
L
S
K
Q
W
I
E
R
-
N
K
E
K
L
V
N
S
K
E
I
R
-
I
I
G
H
S
-
D
I
-----------
Y
G
D
T
L
E
A
A
L
K
L
L
E
T
M
R
I
P
V
T
G
Y
E
F
E
E
F
--
I
H
G
I
Y
N
A
I
N
-
S
D
----
S
T
I
F
I
L
--
D
T
G
K
-
E
P
R
V
T
K
M
I
D
--
V
L
S
G
-
W
T
E
N
V
F
A
I
G
R
D
V
T
E
N
D
K
N
L
K
I
D
I
T
D
N
P
Y
Y
Q
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
33.24
20%
107
- C5 -
3FTJ
-
MACB_AGGAC
A:
[376-499]
--------------------------------------------------------------------------------------------------------------------------------------------
S
A
N
L
Y
G
I
G
E
Q
Y
F
D
V
E
-
G
L
K
L
K
Q
G
R
L
L
-
T
E
D
D
V
D
Q
-----
S
N
Q
---
V
V
V
L
D
-
E
S
A
-
K
K
A
I
F
A
N
----------------------------
E
N
P
-----------
L
G
K
T
V
I
F
N
--------------
K
-
R
P
F
R
-
V
I
G
V
V
S
D
Q
-------
S
L
N
L
Y
S
P
--
Y
S
T
V
L
N
K
-
I
--------
T
G
G
-
S
R
I
G
S
I
T
V
K
I
S
D
D
V
N
S
T
V
A
E
K
S
L
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
32.07
0%
-253
* C5 *
2L66
-
?
A:
[11-26]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
N
Y
---
Q
V
T
I
P
-
A
K
V
-
R
Q
K
F
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
31.14
15%
61
- C5 -
3IS6
2
?
A:
[78-200]
---------------------------------------------------------------------------------------------------------------------------------------------
T
K
T
L
L
A
E
P
A
F
L
D
M
F
-
G
V
E
L
I
A
G
V
-
R
D
S
AL---
R
-----
D
N
M
---
T
C
L
I
S
-
E
S
L
-
A
R
K
M
G
G
------------------------------
D
V
-----------
L
G
K
R
L
R
P
A
E
S
K
----------
S
D
-
R
A
I
T
-
I
G
G
V
F
E
D
L
P
H
N
S
S
-
I
Q
A
D
M
L
L
P
--
I
T
W
M
-
P
A
-
E
S
---
L
--
N
N
W
I
G
N
D
R
Y
I
A
Y
V
R
L
R
P
G
V
S
P
E
S
L
D
E
A
L
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
29.17
30%
5
- C4 -
1B78
-
NTPA_METJA
A:
[10-98]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
-
I
Y
F
A
T
G
N
P
N
K
I
K
E
A
N
I
I
L
K
D
L
-----------
K
D
V
E
I
E
Q
I
K
I
S
Y
P
E
I
Q
G
T
L
E
E
V
A
E
F
G
A
K
W
V
Y
N
I
L
K
K
P
V
---
I
V
E
D
S
G
F
F
V
E
AL
N
G
F
P
-
G
T
-
Y
S
K
F
V
Q
--
E
T
I
G
-
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
28.91
30%
14
- C4 -
2MJP
1
NTPA_METJA
A:
[10-98]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
-
I
Y
F
A
T
G
N
P
N
K
I
K
E
A
N
I
I
L
K
D
L
-----------
K
D
V
E
I
E
Q
I
K
I
S
Y
P
E
I
Q
G
T
L
E
E
V
A
E
F
G
A
K
W
V
Y
N
I
L
K
K
P
V
---
I
V
E
D
S
G
F
F
V
E
AL
N
G
F
P
-
G
T
-
Y
S
K
F
V
Q
--
E
T
I
G
-
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
28.67
37%
-6
- C4 -
2COK
-
A:
[27-68]
-------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
V
K
A
M
I
E
K
L
G
G
K
-
L
-
T
-----
G
-----
T
A
N
---
K
A
S
L
C
--------
I
S
T
K
K
E
V
E
K
M
N
K
K
-
M
E
E
V
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
28.42
12%
-128
- C5 -
1YFB
-
ABRB_BACSU
A:
[13-29]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
-----
E
L
G
---
R
V
V
I
P
-
I
E
L
-
R
R
T
L
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
28.24
23%
-30
- C4 -
2X4D
1
LHPP_HUMAN
A:
[43-148]
------------------------------------------
R
L
K
R
S
R
L
K
V
R
F
C
T
N
E
S
A
A
S
R
A
E
L
V
G
Q
L
Q
R
L
G
F
----
D
I
S
E
Q
E
V
T
A
P
A
P
A
A
C
Q
I
L
K
E
R
G
L
R
P
Y
----
L
L
I
H
D
G
V
--
R
S
E
F
D
Q
I
D
T
S
N
P
N
C
V
V
I
---
A
D
A
G
E
S
F
S
Y
Q
N
M
N
-
N
A
F
Q
V
L
M
E
L
E
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
26.27
36%
-
- C4 -
3VU5
-
?
B:
[4-23]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
E
E
W
D
K
K
-
I
E
E
Y
T
K
K
I
E
E
L
I
K
K
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
26.01
12%
19
- C4 -
1XOU
-
?
B:
[2-85]
----------------------------------------------------------------------------------------------------------------
G
I
V
--
S
Q
T
R
N
K
E
L
L
D
K
K
I
R
S
E
I
E
A
I
K
K
I
I
A
E
F
D
V
V
K
E
S
-
V
N
E
L
S
E
K
A
K
T
D
P
Q
-
A
-
A
-----
E
-----
K
L
N
---
K
L
I
E
G
-
Y
T
Y
G
E
E
R
K
L
Y
D
S
A
L
S
K
I
E
K
L
-
I
E
T
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
25.96
21%
-140
- C4 -
4FXE
2
RELB_ECOLI
A:
[12-45]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
A
R
S
Y
A
A
L
E
K
M
G
V
T
P
S
E
A
L
R
L
M
--
L
E
Y
I
A
D
N
E
R
L
P
--------------------------------------------------------------------------------------------------------------------------------
19
Fugue
25.16
17%
39
* C4 *
4L2W
-
ROCK1_HUMAN
A:
[837-903]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
Q
-
M
-
R
-----
E
-----
L
Q
D
---
Q
L
E
A
E
-
Q
Y
F
-
S
T
--
L
Y
K
T
Q
V
K
E
L
K
E
E
-
I
E
E
K
N
R
E
N
L
K
K
I
Q
E
L
Q
N
A
A
A
T
-----------
L
A
T
Q
L
D
L
A
E
T
K
A
E
S
E
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
24.92
19%
56
- C4 -
1HF9
-
B:
[1-41]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
-
L
-----
K
-----
K
H
H
---
E
N
E
I
S
-
H
H
A
-
K
E
I
E
R
L
Q
K
E
I
E
R
H
K
Q
S
-
I
K
K
L
K
Q
S
E
D
D
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
23.90
19%
56
- C4 -
1HF9
-
ATIF1_BOVIN
A:
[1-41]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
-
L
-----
K
-----
K
H
H
---
E
N
E
I
S
-
H
H
A
-
K
E
I
E
R
L
Q
K
E
I
E
R
H
K
Q
S
-
I
K
K
L
K
Q
S
E
D
D
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------