@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu30450: (2016-07-20 )
MIELRQLSKAIDGNQVLKDVSLTIEKGEIFGLLGRNGSGKTTMLRLIQQIIFADSGTILFDGVEIKKHPKVKQNIIYMPVQNPFYDKYTYKQLVDILRRIYPKFDVTYANELMNRYEIPETKKYRELSTGLKKQLSLVLSFAARPALILLDEPTDGIDAVTRHDVLQLMVDEVAERDTSILITSHRLEDIERMCNRIGFLEDNSLTNVMDLDELKEEYIKIQMAFDTDVNLAIREQNIPMLDQAGVFYTVLIPKSDEEKKSFLRELKPKVWNELPVNLEEVFIAKFGGKRRW
Atome Classification :
(20 SA)
.........10.-.-----......20........30........40........50........60...---...----.------.-70-........80..-......-90---------.....---------..---.100.---.---.---....110.....-------..---120-.--.--.----------....130.......140.......150.......160.......170..-.....180.......190.......200...-....210.......220-........230.......240........250.......260.......270.......280.......290
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MI
E
L
R
Q
L
S
K
AID-G-----
N
Q
V
L
K
D
V
S
L
T
I
EKG
E
I
F
G
L
LGRNGS
G
K
T
T
M
L
R
L
I
Q
Q
I
IFADS
G
T
I
L
F
DGVE---IKK----H------P-KV-KQ
N
I
I
Y
MPVQNP-FYDKY
T
-
Y
K
---------
Q
L
V
D
I
---------
L
R
---
R
IYPK---F---
D
---
V
T
Y
A
N
E
L
M
N
R
YE-------IP---
E
T
K
-
K
--
Y
--
R
----------
E
L
S
T
G
L
K
K
Q
L
S
L
V
L
S
FAAR
P
A
L
I
L
L
DEPTD
G
I
D
A
V
T
R
H
D
V
L
Q
L
M
V
D
E
V
A-ERD
T
S
I
L
I
T
S
H
R
L
E
D
I
E
R
M
C
N
RIGFLEDNSL-TNVM
D
L
D
E
L
K
E
E
Y
I
K
I
--
Q
M
A
FDTDV
N
L
A
I
REQNIPML-DQA
G
V
F
Y
T
V
L
IPKS
D
E
E
K
K
S
F
L
R
E
L
K
P
K
V
W
N
ELPV
N
L
E
E
V
F
I
A
K
FGGKRRW
7
PsiBlast_PDB
74.30
24%
-55
- C1 -
4RVC
-
?
A:
[3-225]
L
L
E
V
K
D
L
S
G
G
Y
T
-
A
-----
Q
N
V
L
E
D
V
T
F
V
V
D
R
G
E
M
V
A
L
I
G
L
N
G
A
G
K
S
T
T
I
K
H
I
I
G
L
M
E
P
R
R
G
A
I
S
I
N
G
Y
R
---
L
A
D
----
G
------
P
-
E
T
Y
R
R
Q
F
A
Y
I
P
E
T
P
V
-
L
Y
E
E
L
T
-
L
E
---------
E
H
L
R
L
---------
A
A
---
M
A
Y
G
L
---
S
---
E
---
A
E
Y
E
R
R
L
P
------------
P
---
L
L
R
-
E
--
F
--
R
LERRLSSFPA
H
F
S
K
G
M
K
Q
K
V
M
I
V
C
A
F
L
L
E
P
P
L
Y
I
I
D
E
P
F
L
G
L
D
P
L
A
I
H
A
L
L
E
R
M
N
E
Q
K
A
--
K
G
A
G
I
L
L
S
T
H
I
L
A
T
A
E
R
Y
C
D
S
F
V
I
L
H
N
G
R
V
-
K
A
K
G
T
L
D
D
I
R
R
Q
F
-----------------------------------------------------------------------------
1
PsiBlast_PDB
70.85
30%
-14
- C1 -
1VPL
2
?
A:
[18-237]
---
V
K
D
L
R
K
R
I
G
-
K
-----
K
E
I
L
K
G
I
S
F
E
I
E
E
G
E
I
F
G
L
I
G
P
N
G
A
G
K
T
T
T
L
R
I
I
S
T
L
I
K
P
S
S
G
I
V
T
V
F
G
K
N
---
V
V
E
----
E
------
P
H
E
V
-
R
K
L
I
S
Y
L
P
E
E
A
G
-
A
Y
R
N
M
-------------
Q
G
I
E
Y
---------
L
R
---
F
V
-
A
G
---
F
---
Y
---
A
S
S
S
S
E
I
E
E
M
V
E
R
A
T
E
I
A
G
L
G
---
E
K
I
-
K
--
D
--
R
VS--------
T
Y
S
K
G
M
V
R
K
L
L
I
A
R
A
L
M
V
N
P
R
L
A
I
L
D
E
P
T
S
G
L
D
V
L
N
A
R
E
V
R
K
I
L
-
K
Q
A
S
-
Q
E
G
L
T
I
L
V
S
S
H
N
M
L
E
V
E
F
L
C
D
R
I
A
L
I
H
N
G
T
I
-
V
E
T
G
T
V
E
E
L
K
E
R
Y
-----------------------------------------------------------------------------
29
HHSearch
68.68
25%
-18
- C1 -
3FVQ
3
FBPC_NEIG1
A:
[4-234]
A
L
H
I
G
H
L
S
K
S
F
Q
-
N
-----
T
P
V
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
G
K
T
---
I
F
S
KN
T
N
L
------
P
-
V
R
-
E
R
R
L
G
Y
L
V
Q
E
G
V
-
L
F
P
H
L
T
-
V
Y
---------
R
N
I
A
Y
---------
G
L
---
G
N
G
K
G
RT
A
Q
---
E
---
R
Q
R
I
E
A
M
L
E
L
T
G
-------
I
S
EL-
A
G
R
-
Y
--
P
--
H
----------
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
-
A
N
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
K
Q
G
R
I
-
L
Q
T
A
S
P
H
E
L
Y
R
Q
------------------------------------------------------------------------------
2
PsiBlast_PDB
68.64
29%
1
- C1 -
4P32
2
LPTB_ECOLI
A:
[6-230]
----
K
N
L
A
K
A
Y
K
-
G
-----
R
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
D
D
ISL
L
P
L
----
H
------
A
-
R
A
-
R
R
G
I
G
Y
L
P
Q
E
A
S
-
I
F
R
R
L
S
V
Y
D
---------
N
L
M
A
V
---------
L
Q
IRD
D
L
S
A
E
---
Q
---
R
---
E
D
R
A
N
E
L
M
E
E
F
H
-------
I
E
---
H
L
R
-
D
--
S
MG
Q
----------
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
-
K
R
I
I
E
H
L
R
-
D
S
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
E
I
L
Q
D
E
H
V
K
---------------------------------------------------------------------------
27
HHSearch
68.37
26%
-40
- C1 -
3D31
-
?
A:
[1-218]
M
I
E
I
E
S
L
S
R
K
W
K
-
N
------
F
S
L
D
N
L
S
L
K
V
E
S
G
E
Y
F
V
I
L
G
P
T
G
A
G
K
T
L
F
L
E
L
I
A
G
F
H
V
P
D
S
G
R
I
L
L
D
G
K
D
---
V
T
D
----
L
------
S
-
P
E
-
K
H
D
I
A
F
V
Y
Q
N
Y
S
-
L
F
P
H
M
N
-
V
K
---------
K
N
L
E
F
---------
G
M
---
R
M
K
K
I
---
K
---
D
---
P
K
R
V
L
D
T
A
R
D
L
K
-------
I
E
HL-
L
D
R
-
N
--
P
--
L
----------
T
L
S
G
G
E
Q
Q
R
V
A
L
A
R
A
L
V
T
N
P
K
I
L
L
L
D
E
P
L
S
A
L
D
P
R
T
Q
E
N
A
R
E
M
L
S
V
L
H
K
-
K
N
K
L
T
V
L
H
I
T
H
D
Q
T
E
A
R
I
M
A
D
R
I
A
V
V
M
D
G
K
L
-
I
Q
V
G
K
P
E
E
I
F
E
K
------------------------------------------------------------------------------
5
PsiBlast_PDB
66.83
28%
1
- C1 -
4P31
2
LPTB_ECOLI
A:
[6-230]
----
K
N
L
A
K
A
Y
K
-
G
-----
R
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
D
D
ISL
L
P
L
----
H
------
A
-
R
A
-
R
R
G
I
G
Y
L
P
Q
E
A
S
-
I
F
R
R
L
S
V
Y
D
---------
N
L
M
A
V
---------
L
Q
IRD
D
L
S
A
E
---
Q
---
R
---
E
D
R
A
N
E
L
M
E
E
F
H
-------
I
E
---
H
L
R
-
D
--
S
MG
Q
----------
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
-
K
R
I
I
E
H
L
R
-
D
S
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
E
I
L
Q
D
E
H
V
K
---------------------------------------------------------------------------
22
HHSearch
66.11
23%
-9
- C1 -
4YER
4
?
A:
[5-307]
I
I
V
V
E
N
L
V
K
K
F
G
-
D
-----
F
E
A
V
K
G
V
S
F
S
V
K
K
G
E
I
F
A
F
L
G
P
N
G
A
G
K
T
T
T
I
H
M
L
T
T
L
L
K
P
T
S
G
K
A
W
V
A
G
H
D
---
V
L
K
----
E
P
-----
R
-
E
V
-
R
R
K
I
G
I
V
F
Q
D
Q
S
-
L
D
R
E
L
T
-
A
Y
---------
E
N
M
Y
I
---------
H
G
---
K
I
Y
G
Y
---
G
---
G
E
K
L
K
K
R
I
L
E
L
L
E
F
V
E
-------
L
L
EF-
K
D
K
-
P
--
V
--
K
----------
T
F
S
G
G
M
A
R
R
L
E
I
A
R
S
L
I
H
E
P
E
V
L
F
L
D
E
P
T
I
G
L
D
P
H
T
R
A
H
M
W
E
Y
I
S
K
-
M
K
K
E
H
N
M
T
I
F
L
T
T
H
Y
M
D
E
A
E
Q
L
A
D
R
V
A
I
I
D
H
G
K
I
-
I
A
L
G
T
P
T
E
L
K
R
M
V
G
K
E
I
I
Y
V
R
-----------
D
F
I
E
S
C
R
K
L
P
D
G
R
L
E
L
N
V
E
D
-------------
I
E
E
I
T
Y
H
K
P
T
L
N
D
V
F
L
H
L
T
G
R
E
L
--
30
HHSearch
65.59
23%
-25
- C1 -
2YYZ
3
?
A:
[3-224]
S
I
R
V
V
N
L
K
K
Y
F
G
-
K
-----
V
K
A
V
D
G
V
S
F
E
V
K
D
G
E
F
V
A
L
L
G
P
S
G
C
G
K
T
T
T
L
L
M
L
A
G
I
Y
K
P
T
S
G
E
I
Y
F
D
D
V
L
---
V
N
D
----
I
------
P
-
P
K
-
Y
R
E
V
G
M
V
F
Q
N
Y
A
-
L
Y
P
H
M
T
-
V
F
---------
E
N
I
A
F
---------
P
L
---
R
A
R
R
I
---
S
KD
E
V
---
E
K
R
V
V
E
I
A
R
K
L
L
-------
I
D
NL-
L
D
R
-
K
--
P
--
T
----------
Q
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
Q
P
K
V
L
L
F
D
E
P
L
S
N
L
D
A
N
L
R
M
I
M
R
A
E
I
K
H
L
Q
Q
-
E
L
G
I
T
S
V
Y
V
T
H
D
Q
A
E
A
M
T
M
A
S
R
I
A
V
F
N
Q
G
K
L
-
V
Q
Y
G
T
P
D
E
V
Y
D
S
------------------------------------------------------------------------------
3
PsiBlast_PDB
65.34
29%
11
- C1 -
4QC2
2
?
A:
[7-231]
----
K
N
L
A
K
A
Y
K
-
G
-----
R
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
D
D
ISL
L
P
L
----
H
------
A
-
R
A
-
R
R
G
I
G
Y
L
P
Q
E
A
S
-
I
F
R
R
L
S
V
Y
D
---------
N
L
M
A
V
---------
L
Q
IRD
D
L
S
A
E
---
Q
---
R
---
E
D
R
A
N
E
L
M
E
E
F
H
-------
I
E
---
H
L
R
-
D
--
S
MG
Q
----------
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
-
K
R
I
I
E
H
L
R
-
D
S
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
E
I
L
Q
D
E
H
V
K
---------------------------------------------------------------------------
34
HHSearch
64.90
21%
-2
- C1 -
4HUQ
-
ECFA2_LACBA
A:
[2-236]
A
I
A
F
E
H
V
T
Y
T
Y
Q
-
A
GTPMA
H
T
A
L
T
D
V
S
L
T
V
P
D
R
G
Y
L
A
I
I
G
H
T
G
S
G
K
S
T
L
I
Q
Q
L
N
A
L
L
K
P
T
S
G
T
I
K
I
D
E
F
T
---
I
T
P
----
E
TTNAAL
K
-
P
L
-
R
Q
H
V
G
M
V
F
Q
F
P
E
N
Q
L
F
E
E
T
-
V
R
---------
Q
D
I
A
F
---------
G
P
---
K
N
F
G
M
---
A
D
A
D
A
---
L
A
L
A
D
E
M
L
T
T
V
G
-------
L
D
QSY
A
E
R
-
S
--
P
--
F
----------
E
L
S
G
G
Q
M
R
R
V
A
I
A
G
V
L
A
M
Q
P
K
V
L
V
L
D
E
P
T
A
G
L
D
P
Q
G
R
Q
E
M
M
R
L
F
A
R
L
H
Q
-
E
Q
G
L
T
I
V
L
V
T
H
Q
M
E
D
V
A
Q
Y
A
E
Q
V
A
V
M
H
E
G
R
L
-
M
K
F
G
T
P
A
D
V
F
S
N
------------------------------------------------------------------------------
6
PsiBlast_PDB
63.56
27%
-31
- C1 -
4WBS
1
?
A:
[42-256]
---
V
R
N
L
K
K
R
Y
G
-
S
-----
R
T
V
V
K
D
V
S
L
D
V
K
S
G
E
V
V
G
L
L
G
P
N
G
A
G
K
T
T
S
F
Y
M
I
V
G
L
V
P
L
D
A
G
E
I
D
L
D
G
K
S
---
I
S
L
LP
I
-
H
------
K
-
R
A
-
S
L
G
L
S
Y
L
P
Q
E
A
S
-
V
F
R
K
L
S
-
V
E
E
N
I
R
A
V
L
E
L
Q
V
G
D
D
---------
G
K
---
R
L
S
K
D
---
A
---
I
---
A
S
R
T
E
A
L
L
D
E
L
Q
-------
I
S
---
H
L
R
-
E
NP
A
--
L
----------
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
T
N
P
S
F
I
L
L
D
E
P
F
A
G
V
D
P
I
A
V
L
E
I
-
Q
K
I
V
K
F
L
K
-
Q
R
N
I
G
V
L
I
T
D
H
N
V
R
E
T
L
G
I
C
D
H
A
Y
I
I
S
D
G
S
V
-------------------------------------------------------------------------------------------
4
PsiBlast_PDB
62.77
28%
9
- C1 -
4P33
7
LPTB_ECOLI
A:
[6-230]
----
K
N
L
A
K
A
Y
K
-
G
-----
R
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
D
D
ISL
L
P
L
----
H
------
A
-
R
A
-
R
R
G
I
G
Y
L
P
Q
E
A
S
-
I
F
R
R
L
S
V
Y
D
---------
N
L
M
A
V
---------
L
Q
IRD
D
L
S
A
E
---
Q
---
R
---
E
D
R
A
N
E
L
M
E
E
F
H
-------
I
E
---
H
L
R
-
D
--
S
MG
Q
----------
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
Q
P
F
A
G
V
D
P
I
S
V
I
D
I
-
K
R
I
I
E
H
L
R
-
D
S
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
E
I
L
Q
D
E
H
V
K
---------------------------------------------------------------------------
16
PsiBlast_PDB
61.00
26%
-51
- C1 -
4YMV
1
?
J:
[1-215]
M
I
F
V
N
D
V
Y
K
N
F
G
-
S
-----
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
---
I
-
N
----
N
------
G
-
K
V
-
N
I
N
K
V
R
Q
K
V
G
M
V
-
F
Q
H
F
N
L
-
F
P
---------
H
L
T
A
I
ENITLAPVK
V
K
---
K
M
N
K
K
---
E
---
A
---
E
E
L
A
V
D
L
L
A
K
V
G
-------
L
L
---
D
K
K
D
Q
--
Y
--
P
I---------
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
-
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
-
V
-----------------------------------------------------------------------------------------
23
HHSearch
59.74
25%
18
- C1 -
1Z47
1
?
A:
[15-236]
-
I
E
F
V
G
V
E
K
I
Y
P
G
G
-----
A
R
S
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
K
R
---
V
T
D
----
L
------
P
-
P
Q
-
K
R
N
V
G
L
V
F
Q
N
Y
A
-
L
F
Q
H
M
T
-
V
Y
---------
D
N
V
S
F
---------
G
L
---
R
E
K
R
V
---
P
K
D
E
M
---
D
A
R
V
R
E
L
L
R
F
M
R
-------
L
E
SY-
A
N
R
-
F
--
P
--
H
----------
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
D
-
E
M
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
L
V
L
H
E
G
N
V
-
E
Q
F
G
T
P
E
E
V
Y
E
K
------------------------------------------------------------------------------
15
PsiBlast_PDB
59.27
26%
-50
- C1 -
4YMU
2
?
J:
[1-215]
M
I
F
V
N
D
V
Y
K
N
F
G
-
S
-----
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
---
I
-
N
----
N
------
G
-
K
V
-
N
I
N
K
V
R
Q
K
V
G
M
V
-
F
Q
H
F
N
L
-
F
P
---------
H
L
T
A
I
ENITLAPVK
V
K
---
K
M
N
K
K
---
E
---
A
---
E
E
L
A
V
D
L
L
A
K
V
G
-------
L
L
---
D
K
K
D
Q
--
Y
--
P
I---------
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
-
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
-
V
-----------------------------------------------------------------------------------------
13
PsiBlast_PDB
59.25
26%
-49
- C1 -
4YMS
-
?
J:
[1-215]
M
I
F
V
N
D
V
Y
K
N
F
G
-
S
-----
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
---
I
-
N
----
N
------
G
-
K
V
-
N
I
N
K
V
R
Q
K
V
G
M
V
-
F
Q
H
F
N
L
-
F
P
---------
H
L
T
A
I
ENITLAPVK
V
K
---
K
M
N
K
K
---
E
---
A
---
E
E
L
A
V
D
L
L
A
K
V
G
-------
L
L
---
D
K
K
D
Q
--
Y
--
P
I---------
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
-
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
-
V
-----------------------------------------------------------------------------------------
31
HHSearch
58.72
20%
-36
- C1 -
3RLF
3
MALK_ECOLI
A:
[3-224]
S
V
Q
L
Q
N
V
T
K
A
W
G
-
E
-----
V
V
V
S
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
E
K
R
---
M
N
D
----
T
------
P
-
P
A
-
E
R
G
V
G
M
V
F
Q
S
Y
A
-
L
Y
P
H
L
S
-
V
A
---------
E
N
M
S
F
---------
G
L
---
K
L
A
G
A
---
K
K
E
V
I
---
N
Q
R
V
N
Q
V
A
E
V
L
Q
-------
L
A
HL-
L
D
R
-
K
--
P
--
K
----------
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
-
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
-
A
Q
V
G
K
P
L
E
L
Y
H
Y
------------------------------------------------------------------------------
14
PsiBlast_PDB
58.43
26%
-50
- C1 -
4YMT
-
?
J:
[1-215]
M
I
F
V
N
D
V
Y
K
N
F
G
-
S
-----
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
---
I
-
N
----
N
------
G
-
K
V
-
N
I
N
K
V
R
Q
K
V
G
M
V
-
F
Q
H
F
N
L
-
F
P
---------
H
L
T
A
I
ENITLAPVK
V
K
---
K
M
N
K
K
---
E
---
A
---
E
E
L
A
V
D
L
L
A
K
V
G
-------
L
L
---
D
K
K
D
Q
--
Y
--
P
I---------
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
-
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
-
V
-----------------------------------------------------------------------------------------
25
HHSearch
58.35
24%
-21
- C1 -
2IT1
-
?
A:
[4-224]
-
I
K
L
E
N
I
V
K
K
F
G
-
N
-----
F
T
A
L
N
N
I
N
L
K
I
K
D
G
E
F
M
A
L
L
G
P
S
G
S
G
K
S
T
L
L
Y
T
I
A
G
I
Y
K
P
T
S
G
K
I
Y
F
D
E
K
D
---
V
T
E
----
L
------
P
-
P
K
-
D
R
N
V
G
L
V
F
Q
N
W
A
-
L
Y
P
H
M
T
-
V
Y
---------
K
N
I
A
F
---------
P
L
---
E
L
R
K
A
---
P
R
E
E
I
---
D
K
K
V
R
E
V
A
K
M
L
H
-------
I
D
KL-
L
N
R
-
Y
--
P
--
W
----------
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
V
K
E
P
E
V
L
L
L
D
E
P
L
S
N
L
D
A
L
L
R
L
E
V
R
A
E
L
K
R
L
Q
K
-
E
L
G
I
T
T
V
Y
V
T
H
D
Q
A
E
A
L
A
M
A
D
R
I
A
V
I
R
E
G
E
I
-
L
Q
V
G
T
P
D
E
V
Y
Y
K
------------------------------------------------------------------------------
33
HHSearch
58.12
23%
4
* C1 *
3TUI
1
METN_ECOLI
C:
[24-254]
M
I
K
L
S
N
I
T
K
V
F
H
-
Q
GTRT-
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
---
L
T
T
----
L
SESEL-
T
-
K
A
-
R
R
Q
I
G
M
I
F
Q
H
F
N
-
L
L
S
S
R
T
-
V
F
---------
G
N
V
A
L
---------
P
L
---
E
L
D
N
T
---
P
---
K
DEV
K
R
R
V
T
E
L
L
S
L
V
G
-------
L
G
DK-
H
D
S
-
Y
--
P
--
S
----------
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
-
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
-
I
E
Q
D
T
V
S
E
V
F
S
H
------------------------------------------------------------------------------