@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu30810: (2016-07-20 )
MGTVNITVSDGVRYAVADEGPNASEAVVCLHGFTGSKQSWTFLDEMLPDSRLIKIDCLGHGETDAPLNGKRYSTTRQVSDLAEIFDQLKLHKVKLIGYSMGGRLAYSFAMTYPERVSALVLESTTPGLKTLGERRERIMRDRKLADFILRDGLEAFVAYWENIPLFSSQQRLAEDIRYRIRSGRLRNNKIGLANSLTGMGTGSQPSLWSRVEEIDVPVLLICGEWDEKFCAINQEVHKMLPSSRIEIVPKAGHTVHVEQPRLFGKIVSEFLTSI
Atome Classification :
(20 SA)
.........10........20.--.......30......-..40.-...-....----.50.........60........70........80........90.-...-------.....100.......110.......120.......130-...--....140.....-..150--......--------..160.......170.........180.---......190.....--..---200.....----.-.-210.......220.......230..-..----....240.......250.......260.......270..
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
G
T
V
N
I
T
VSD
G
V
R
Y
A
VADEGPN--AS
E
A
V
V
C
L
HGFTGSK-
Q
S
W
-
T
-
F
L
D
-
E
MLP----DS-
R
L
I
K
I
D
C
LGHGETDAPLNGKRYS
T
T
R
Q
V
S
D
L
A
E
I
F
D
Q
LK
L
-
H
-
K
V
K
-------
L
I
G
YSMG
G
R
L
A
Y
S
F
AMT
Y
P
E
R
V
S
A
L
V
LESTT
P
G
L
K
T
L
G
-
E
R
R
--
E
R
I
M
R
D
R
K
L
A
D
F
-
I
L
R
D
---
G
L
E
A
F
V
--------
A
Y
W
ENIPLF
S
S
Q
Q
--
R
L
A
E
D
I
R
Y
R
I
RSG---RLRNNKIGLANSLT--GM---GTGSQ
P
S
L
----
W
-
S
-
R
V
E
EIDV
P
V
L
L
I
CGEW
D
E
K
F
C
-
A
I
N
-
Q
E
----
V
H
K
MLPSS
R
I
E
I
V
PKAG
H
T
V
HVE
Q
P
R
L
F
G
K
I
V
S
E
F
L
TSI
112
HHSearch
81.44
34%
-3
- C- -
2XMZ
-
?
A:
[7-263]
----------------
Y
E
A
N
V
E
--
T
N
Q
V
L
V
F
L
H
G
F
L
S
D
S
-
R
T
Y
-
H
N
H
I
E
-
K
F
T
D
----
N
Y
-
H
V
I
T
I
D
L
P
G
H
G
E
D
Q
S
S
M
D
-
E
T
W
N
F
D
Y
I
T
T
L
L
D
R
I
L
D
K
Y
K
D
-
K
-
S
I
T
-------
L
F
G
Y
S
M
G
G
R
V
A
L
Y
Y
A
I
N
G
H
I
P
I
S
N
L
I
L
E
S
T
S
P
G
I
K
E
E
A
-
N
Q
L
--
E
R
R
L
V
D
D
A
R
A
K
V
-
L
D
I
A
---
G
I
E
L
F
V
--------
N
D
W
E
K
L
P
L
F
Q
S
Q
L
--
E
L
P
V
E
I
Q
H
Q
I
R
Q
Q
---
R
L
S
Q
S
P
H
K
M
A
K
A
L
R
--
D
Y
---
G
T
G
Q
M
P
N
L
----
W
-
P
-
R
L
K
E
I
K
V
P
T
L
I
L
A
G
E
Y
D
E
K
F
V
-
Q
I
A
-
K
K
----
M
A
N
L
I
P
N
S
K
C
K
L
I
S
A
T
G
H
T
I
H
V
E
D
S
D
E
F
D
T
M
I
L
G
F
L
K
E
-
1
PsiBlast_PDB
79.07
34%
-7
- C- -
2XMZ
-
?
A:
[2-261]
-----------
T
H
Y
K
F
Y
E
A
N
V
E
--
T
N
Q
V
L
V
F
L
H
G
F
L
S
D
S
-
R
T
Y
H
N
-
H
I
E
-
K
F
T
D
----
N
Y
-
H
V
I
T
I
D
L
P
G
H
G
E
D
Q
S
S
M
D
-
E
T
W
N
F
D
Y
I
T
T
L
L
D
R
I
L
D
K
Y
K
D
-
K
-
S
I
T
-------
L
F
G
Y
S
M
G
G
R
V
A
L
Y
Y
A
I
N
G
H
I
P
I
S
N
L
I
L
E
S
T
S
P
G
I
K
E
E
A
-
N
Q
L
--
E
R
R
L
V
D
D
A
R
A
K
V
-
L
D
I
A
---
G
I
E
L
F
V
--------
N
D
W
E
K
L
P
L
F
Q
S
Q
L
--
E
L
P
V
E
I
Q
H
Q
I
R
Q
Q
---
R
L
S
Q
S
P
H
K
M
A
K
A
L
R
--
D
Y
---
G
T
G
Q
M
P
N
L
----
W
-
P
-
R
L
K
E
I
K
V
P
T
L
I
L
A
G
E
Y
D
E
K
F
V
-
Q
I
A
-
K
K
----
M
A
N
L
I
P
N
S
K
C
K
L
I
S
A
T
G
H
T
I
H
V
E
D
S
D
E
F
D
T
M
I
L
G
F
L
---
102
Fugue
74.08
27%
-113
- C1 -
4MYD
1
MENH_ECOLI
A:
[1-252]
----------
M
I
L
H
A
Q
A
K
H
G
K
P
--
G
L
P
W
L
V
F
L
H
G
F
S
G
D
C
-
H
E
W
-
Q
-
E
V
G
-
E
A
F
A
----
D
Y
-
S
R
L
Y
V
D
L
P
G
H
G
G
S
A
A
I
---
S
V
D
G
F
D
D
V
T
D
L
L
R
K
T
L
V
S
Y
N
I
-
L
-
D
F
W
-------
L
V
G
Y
S
L
G
G
R
V
A
M
M
A
A
C
Q
G
L
A
G
L
C
G
V
I
V
E
G
G
H
P
G
L
Q
N
A
E
-
Q
R
A
--
E
R
Q
R
S
D
R
Q
W
V
Q
R
-
F
L
T
E
---
P
L
T
A
V
F
--------
A
D
W
Y
Q
Q
P
V
F
A
S
L
N
--
D
D
Q
R
R
E
L
V
A
L
R
S
------
N
N
N
G
A
T
L
A
A
M
L
E
--
A
T
---
S
L
A
V
Q
P
D
L
----
R
-
A
-
N
L
S
A
R
T
F
A
F
Y
Y
L
C
G
E
R
D
S
K
F
R
-
A
L
A
-
A
E
----
L
-----
A
A
D
C
H
V
I
P
R
A
G
H
N
A
H
R
E
N
P
A
G
V
I
A
S
L
A
Q
I
L
R
F
-
111
HHSearch
65.68
24%
-34
- C1 -
3OM8
2
?
A:
[9-266]
-----
L
A
T
S
D
G
A
S
L
A
Y
R
L
D
G
A
A
--
E
K
P
L
L
A
L
S
N
S
I
G
T
T
L
-
H
M
W
-
D
A
Q
L
P
-
A
L
T
R
----
H
F
-
R
V
L
R
Y
D
A
R
G
H
G
A
S
S
V
P
P
--
G
P
Y
T
L
A
R
L
G
E
D
V
L
E
L
L
D
A
L
E
V
-
R
-
R
A
H
-------
F
L
G
L
S
L
G
G
I
V
G
Q
W
L
A
L
H
A
P
Q
R
I
E
R
L
V
L
A
N
T
S
A
W
L
G
P
A
A
-
Q
W
D
--
E
R
I
-
A
A
V
L
Q
A
E
D
-
M
-
S
E
---
T
A
A
G
F
L
--------
G
N
W
F
P
P
A
L
L
E
-----
R
A
E
P
V
V
E
R
F
R
A
-
M
---
L
M
A
T
N
R
H
G
L
A
G
S
F
A
--
A
V
------
R
D
T
D
L
----
R
-
A
-
Q
L
A
R
I
E
R
P
T
L
V
I
A
G
A
Y
D
T
V
T
A
A
S
H
G
-
E
L
----
I
A
A
S
I
A
G
A
R
L
V
T
L
P
-
A
V
H
L
S
N
V
E
F
P
Q
A
F
E
G
A
V
L
S
F
L
G
A
-
15
PsiBlast_PDB
56.80
24%
0
- C- -
4NS4
-
?
A:
[18-297]
L
T
T
Q
S
F
T
L
S
S
G
D
K
I
V
Y
A
E
N
G
N
V
--
A
G
E
P
L
L
L
V
H
G
F
G
G
N
K
-
D
N
F
-
T
-
R
I
A
-
R
Q
L
E
----
N
Y
-
N
L
I
I
P
D
L
L
G
F
G
D
S
S
K
P
M
-
A
A
D
Y
H
S
E
A
Q
A
T
R
L
H
E
L
L
Q
A
K
G
L
A
S
-
S
I
H
-------
V
G
G
N
S
M
G
G
A
I
S
V
A
Y
A
A
K
Y
P
K
E
V
K
S
L
W
L
I
D
S
A
-
G
F
W
S
--------------------P
L
L
V
D
---
K
K
E
D
F
Y
--------
A
M
Y
D
F
V
--
M
S
K
P
P
--
Y
I
P
K
S
V
K
A
V
F
A
Q
E
---
R
I
A
N
K
A
L
E
-
S
K
I
L
A
--
Q
I
---
V
E
D
N
V
E
Q
R
----
A
-
K
-
V
I
T
E
Y
N
I
P
T
L
V
V
W
G
E
E
D
K
----
V
I
K
-
P
E
T
V
T
L
I
K
E
I
I
P
Q
S
Q
V
I
T
M
P
K
I
G
H
V
P
M
I
E
----------------
2
PsiBlast_PDB
56.02
28%
-43
- C1 -
4MXD
6
MENH_ECOLI
A:
[5-242]
-----------
I
L
H
A
Q
A
K
H
G
K
P
--
G
L
P
W
L
V
F
L
H
G
F
S
G
D
C
-
H
E
W
-
Q
-
E
V
G
-
E
A
F
A
----
D
Y
-
S
R
L
Y
V
D
L
P
G
H
G
G
----------
S
A
A
I
S
V
D
G
F
D
D
V
T
D
L
L
R
K
-
T
-
L
V
S
Y
NIL
D
F
W
L
V
G
Y
S
L
G
G
R
V
A
M
M
A
A
C
Q
G
L
A
G
L
C
G
V
I
V
E
G
G
H
P
G
L
Q
N
A
E
-
Q
R
A
--
E
R
Q
R
S
D
R
Q
W
V
Q
R
-
F
L
T
E
---
P
L
T
A
V
F
--------
A
D
W
Y
Q
Q
P
V
F
A
S
-----
L
N
D
D
Q
R
R
E
L
V
A
L
---
R
S
N
N
N
G
A
T
L
A
A
M
L
E
--
A
T
---
S
L
A
V
Q
P
D
L
----
R
-
A
-
N
L
S
A
R
T
F
A
F
Y
Y
L
C
G
E
R
D
S
K
F
R
-
A
L
A
-
A
E
----
L
-----
A
A
D
C
H
V
I
P
R
A
G
H
N
A
H
R
E
N
P
--------------
4
PsiBlast_PDB
55.55
28%
-36
- C1 -
4MYS
2
MENH_ECOLI
A:
[2-239]
-----------
I
L
H
A
Q
A
K
H
G
K
P
--
G
L
P
W
L
V
F
L
H
G
F
S
G
D
C
-
H
E
W
-
Q
-
E
V
G
-
E
A
F
A
----
D
Y
-
S
R
L
Y
V
D
L
P
G
H
G
G
----------
S
A
A
I
S
V
D
G
F
D
D
V
T
D
L
L
R
K
-
T
-
L
V
S
Y
NIL
D
F
W
L
V
G
Y
S
L
G
G
R
V
A
M
M
A
A
C
Q
G
L
A
G
L
C
G
V
I
V
E
G
G
H
P
G
L
Q
N
A
E
-
Q
R
A
--
E
R
Q
R
S
D
R
Q
W
V
Q
R
-
F
L
T
E
---
P
L
T
A
V
F
--------
A
D
W
Y
Q
Q
P
V
F
A
S
-----
L
N
D
D
Q
R
R
E
L
V
A
L
---
R
S
N
N
N
G
A
T
L
A
A
M
L
E
--
A
T
---
S
L
A
V
Q
P
D
L
----
R
-
A
-
N
L
S
A
R
T
F
A
F
Y
Y
L
C
G
E
R
D
S
K
F
R
-
A
L
A
-
A
E
----
L
-----
A
A
D
C
H
V
I
P
R
A
G
H
N
A
H
R
E
N
P
--------------
14
PsiBlast_PDB
55.21
26%
-6
- C1 -
3OM8
2
?
A:
[9-264]
-----
L
A
T
S
D
G
A
S
L
A
Y
R
L
D
G
-
A
--
A
E
K
P
L
L
A
L
S
N
S
I
G
T
T
L
H
M
W
-----
D
-
A
Q
L
P
A
L
T
R
H
F
-
R
V
L
R
Y
D
A
R
G
H
G
A
S
S
V
P
P
G
--
P
Y
T
L
A
R
L
G
E
D
V
L
E
L
L
D
A
L
E
V
-
R
-
R
A
H
-------
F
L
G
L
S
L
G
G
I
V
G
Q
W
L
A
L
H
A
P
Q
R
I
E
R
L
V
L
A
N
T
S
A
W
L
G
P
A
A
-
Q
W
D
--
E
R
I
A
A
V
L
Q
A
E
D
---
M
S
E
---
T
A
A
G
F
L
--------
G
N
W
F
P
P
A
L
L
E
R
------
A
E
P
V
V
E
R
F
R
A
M
---
L
M
A
T
N
R
H
G
L
A
G
S
F
A
--
A
V
------
R
D
T
D
L
----
R
-
A
-
Q
L
A
R
I
E
R
P
T
L
V
I
A
G
A
Y
D
T
V
T
A
-
A
S
H
-
G
E
L
---
I
A
A
S
I
A
G
A
R
L
V
T
L
P
-
A
V
H
L
S
N
V
E
F
P
Q
A
F
E
G
A
V
L
S
F
L
---
19
PsiBlast_PDB
53.86
27%
-4
- C1 -
4UHC
2
?
A:
[29-271]
----------------------------
V
L
L
V
H
G
F
P
L
D
R
-
T
M
W
-
K
-
A
Q
R
-
E
E
L
C
----
D
E
F
R
V
I
V
P
D
L
R
G
F
G
E
S
Q
V
-
I
P
G
V
-
A
T
M
E
A
M
A
D
D
L
A
G
L
C
N
H
L
G
L
-
T
G
K
I
V
-------
L
G
G
L
S
M
G
G
Y
V
A
F
A
F
A
R
K
Y
R
D
R
L
A
G
L
I
L
C
D
T
----
R
A
R
P
-
D
S
P
--
E
A
K
E
N
R
R
R
V
A
E
R
-
V
R
R
E
---
G
-
P
G
F
I
--------
A
E
-
E
M
I
P
R
L
C
C
E
S
T
F
R
N
H
P
E
V
I
E
K
I
R
Q
M
---
I
L
S
A
P
P
E
G
V
A
A
A
A
L
--
G
M
-----
A
E
R
P
D
S
----
T
-
D
-
L
L
P
A
L
S
C
P
T
L
V
L
V
G
Q
F
D
A
I
S
P
-
P
E
E
-
M
E
A
---
M
A
R
T
I
P
Q
S
Q
F
V
V
I
P
D
A
G
H
L
P
P
M
E
Q
P
E
R
V
T
Q
A
I
R
E
W
L
R
K
V
121
HHSearch
53.70
22%
-37
- C1 -
4CCY
2
YBFK_BACSU
A:
[36-293]
----
Y
V
S
T
R
-
F
G
K
T
H
I
I
A
S
G
P
K
--
D
A
P
S
L
I
L
L
H
G
G
L
F
S
S
-
A
M
W
-
Y
P
N
I
A
-
A
W
S
S
----
Q
F
-
R
T
Y
A
V
D
I
I
G
D
K
N
K
S
I
P
S
A
-
A
M
E
T
R
A
D
F
A
E
W
M
K
D
V
F
D
S
L
G
L
-
E
-
T
A
H
-------
L
A
G
L
S
L
G
G
S
H
I
V
N
F
L
L
R
A
P
E
R
V
E
R
A
V
V
I
S
P
A
E
A
F
I
S
F
H
-
P
D
V
--
Y
K
Y
A
-----
A
E
L
-
T
G
A
R
---
G
A
E
S
Y
I
--------
K
-
W
I
T
G
D
S
Y
D
-----
L
H
P
L
L
Q
R
Q
I
V
A
G
V
---
E
W
Q
D
E
Q
R
S
L
K
P
T
E
N
--
G
F
------
P
Y
V
F
T
----
D
-
Q
-
E
L
K
S
I
Q
V
P
V
L
L
M
F
G
E
H
E
A
M
Y
H
Q
Q
M
A
F
E
R
----
A
S
V
L
V
P
G
I
Q
A
E
I
V
K
N
A
G
H
L
L
S
L
E
Q
P
E
Y
V
N
Q
R
V
L
S
F
L
C
G
-
20
PsiBlast_PDB
53.54
27%
-2
- C1 -
4UHD
5
?
A:
[29-271]
----------------------------
V
L
L
V
H
G
F
P
L
D
R
-
T
M
W
-
K
-
A
Q
R
-
E
E
L
C
----
D
E
F
R
V
I
V
P
D
L
R
G
F
G
E
S
Q
V
-
I
P
G
V
-
A
T
M
E
A
M
A
D
D
L
A
G
L
C
N
H
L
G
L
-
T
G
K
I
V
-------
L
G
G
L
S
M
G
G
Y
V
A
F
A
F
A
R
K
Y
R
D
R
L
A
G
L
I
L
C
D
T
----
R
A
R
P
-
D
S
P
--
E
A
K
E
N
R
R
R
V
A
E
R
-
V
R
R
E
---
G
-
P
G
F
I
--------
A
E
-
E
M
I
P
R
L
C
C
E
S
T
F
R
N
H
P
E
V
I
E
K
I
R
Q
M
---
I
L
S
A
P
P
E
G
V
A
A
A
A
L
--
G
M
-----
A
E
R
P
D
S
----
T
-
D
-
L
L
P
A
L
S
C
P
T
L
V
L
V
G
Q
F
D
A
I
S
P
-
P
E
E
-
M
E
A
---
M
A
R
T
I
P
Q
S
Q
F
V
V
I
P
D
A
G
H
L
P
P
M
E
Q
P
E
R
V
T
Q
A
I
R
E
W
L
R
K
V
3
PsiBlast_PDB
53.45
28%
-36
- C1 -
4MYD
1
MENH_ECOLI
A:
[2-239]
-----------
I
L
H
A
Q
A
K
H
G
K
P
--
G
L
P
W
L
V
F
L
H
G
F
S
G
D
C
-
H
E
W
-
Q
-
E
V
G
-
E
A
F
A
----
D
Y
-
S
R
L
Y
V
D
L
P
G
H
G
G
----------
S
A
A
I
S
V
D
G
F
D
D
V
T
D
L
L
R
K
-
T
-
L
V
S
Y
NIL
D
F
W
L
V
G
Y
S
L
G
G
R
V
A
M
M
A
A
C
Q
G
L
A
G
L
C
G
V
I
V
E
G
G
H
P
G
L
Q
N
A
E
-
Q
R
A
--
E
R
Q
R
S
D
R
Q
W
V
Q
R
-
F
L
T
E
---
P
L
T
A
V
F
--------
A
D
W
Y
Q
Q
P
V
F
A
S
-----
L
N
D
D
Q
R
R
E
L
V
A
L
---
R
S
N
N
N
G
A
T
L
A
A
M
L
E
--
A
T
---
S
L
A
V
Q
P
D
L
----
R
-
A
-
N
L
S
A
R
T
F
A
F
Y
Y
L
C
G
E
R
D
S
K
F
R
-
A
L
A
-
A
E
----
L
-----
A
A
D
C
H
V
I
P
R
A
G
H
N
A
H
R
E
N
P
--------------
5
PsiBlast_PDB
53.18
28%
-34
- C1 -
4GDM
2
MENH_ECOLI
A:
[18-255]
-----------
I
L
H
A
Q
A
K
H
G
K
P
--
G
L
P
W
L
V
F
L
H
G
F
S
G
D
C
-
H
E
W
-
Q
-
E
V
G
-
E
A
F
A
----
D
Y
-
S
R
L
Y
V
D
L
P
G
H
G
G
----------
S
A
A
I
S
V
D
G
F
D
D
V
T
D
L
L
R
K
-
T
-
L
V
S
Y
NIL
D
F
W
L
V
G
Y
S
L
G
G
R
V
A
M
M
A
A
C
Q
G
L
A
G
L
C
G
V
I
V
E
G
G
H
P
G
L
Q
N
A
E
-
Q
R
A
--
E
R
Q
R
S
D
R
Q
W
V
Q
R
-
F
L
T
E
---
P
L
T
A
V
F
--------
A
D
W
Y
Q
Q
P
V
F
A
S
-----
L
N
D
D
Q
R
R
E
L
V
A
L
---
R
S
N
N
N
G
A
T
L
A
A
M
L
E
--
A
T
---
S
L
A
V
Q
P
D
L
----
R
-
A
-
N
L
S
A
R
T
F
A
F
Y
Y
L
C
G
E
R
D
S
K
F
R
-
A
L
A
-
A
E
----
L
-----
A
A
D
C
H
V
I
P
R
A
G
H
N
A
H
R
E
N
P
--------------
6
PsiBlast_PDB
53.14
28%
-33
- C1 -
4GEG
6
MENH_ECOLI
A:
[18-255]
-----------
I
L
H
A
Q
A
K
H
G
K
P
--
G
L
P
W
L
V
F
L
H
G
F
S
G
D
C
-
H
E
W
-
Q
-
E
V
G
-
E
A
F
A
----
D
Y
-
S
R
L
Y
V
D
L
P
G
H
G
G
----------
S
A
A
I
S
V
D
G
F
D
D
V
T
D
L
L
R
K
-
T
-
L
V
S
Y
NIL
D
F
W
L
V
G
F
S
L
G
G
R
V
A
M
M
A
A
C
Q
G
L
A
G
L
C
G
V
I
V
E
G
G
H
P
G
L
Q
N
A
E
-
Q
R
A
--
E
R
Q
R
S
D
R
Q
W
V
Q
R
-
F
L
T
E
---
P
L
T
A
V
F
--------
A
D
W
Y
Q
Q
P
V
F
A
S
-----
L
N
D
D
Q
R
R
E
L
V
A
L
---
R
S
N
N
N
G
A
T
L
A
A
M
L
E
--
A
T
---
S
L
A
V
Q
P
D
L
----
R
-
A
-
N
L
S
A
R
T
F
A
F
Y
Y
L
C
G
E
R
D
S
K
F
R
-
A
L
A
-
A
E
----
L
-----
A
A
D
C
H
V
I
P
R
A
G
H
N
A
H
R
E
N
P
--------------
7
PsiBlast_PDB
52.23
28%
-32
- C1 -
4GEC
5
MENH_ECOLI
A:
[18-255]
-----------
I
L
H
A
Q
A
K
H
G
K
P
--
G
L
P
W
L
V
F
L
H
G
F
S
G
D
C
-
H
E
W
-
Q
-
E
V
G
-
E
A
F
A
----
D
Y
-
S
R
L
Y
V
D
L
P
G
H
G
G
----------
S
A
A
I
S
V
D
G
F
D
D
V
T
D
L
L
R
K
-
T
-
L
V
S
Y
NIL
D
F
W
L
V
G
Y
S
L
G
G
R
V
A
M
M
A
A
C
Q
G
L
A
G
L
C
G
V
I
V
E
G
G
H
P
G
L
Q
N
A
E
-
Q
R
A
--
E
A
Q
R
S
D
R
Q
W
V
Q
R
-
F
L
T
E
---
P
L
T
A
V
F
--------
A
D
W
Y
Q
Q
P
V
F
A
S
-----
L
N
D
D
Q
R
R
E
L
V
A
L
---
R
S
N
N
N
G
A
T
L
A
A
M
L
E
--
A
T
---
S
L
A
V
Q
P
D
L
----
R
-
A
-
N
L
S
A
R
T
F
A
F
Y
Y
L
C
G
E
R
D
S
K
F
R
-
A
L
A
-
A
E
----
L
-----
A
A
D
C
H
V
I
P
R
A
G
H
N
A
H
R
E
N
P
--------------
116
HHSearch
51.16
20%
-42
- C1 -
4CCW
1
?
A:
[36-292]
----
Y
I
S
T
-
R
F
G
Q
T
H
V
I
A
S
G
P
E
--
D
A
P
P
L
V
L
L
H
G
A
L
F
S
S
-
T
M
W
-
Y
P
N
I
A
-
D
W
S
S
----
K
Y
-
R
T
Y
A
V
D
I
I
G
D
K
N
K
S
I
P
E
N
-
L
S
G
T
R
T
D
Y
A
N
W
L
L
D
V
F
D
N
L
G
I
-
E
-
K
S
H
-------
M
I
G
L
S
L
G
G
L
H
T
M
N
F
L
L
R
M
P
E
R
V
K
S
A
A
I
L
S
P
A
E
T
F
L
P
F
H
-
H
D
F
--
Y
K
Y
A
L
-----
G
L
-
T
A
S
N
---
G
V
E
K
F
L
--------
N
W
M
M
T
D
Q
N
V
------
L
H
P
I
F
V
K
Q
F
Q
A
G
V
---
M
W
Q
D
G
S
R
N
P
N
P
K
A
D
--
G
F
------
P
Y
V
F
T
----
D
-
E
-
E
L
R
S
A
R
V
P
I
L
L
L
L
G
E
H
E
V
I
Y
D
P
H
S
A
L
H
R
----
A
S
S
F
V
P
D
I
E
A
E
V
I
K
N
A
G
H
V
L
S
M
E
Q
P
A
Y
V
N
E
R
V
M
R
F
F
N
--
119
HHSearch
50.99
20%
-10
- C1 -
4PW0
6
?
A:
[21-283]
--------
V
N
G
T
R
Y
A
Y
R
S
L
G
A
P
--
S
D
I
P
L
I
C
F
Q
H
F
T
G
T
L
-
D
N
W
-
D
P
L
I
T
N
G
L
S
K
----
G
R
-
Q
L
I
I
F
D
N
K
G
V
G
L
S
S
G
T
T
---
P
D
N
V
A
A
M
T
A
D
A
L
E
F
I
T
A
L
G
I
-
R
-
Y
F
D
-------
V
L
G
F
S
L
G
G
F
I
V
Q
Y
M
A
H
I
Q
P
D
M
I
R
K
I
I
I
V
G
A
A
P
Q
G
V
K
V
L
-
H
T
F
--
P
D
L
I
A
--
R
A
M
Q
L
----
E
---
P
K
E
R
F
L
--------
F
I
F
F
E
Q
S
E
H
S
R
S
K
--
G
L
A
T
L
G
-
R
L
Y
E
R
T
TDR
D
Q
D
A
S
A
Q
A
I
G
A
Q
L
T
--
A
I
---
T
N
W
G
K
K
T
P
----
S
-
F
-
E
I
T
S
I
Q
H
P
V
F
V
V
Q
G
S
N
D
E
M
M
D
T
Y
N
S
-
Y
E
----
L
F
K
Q
L
P
D
A
I
L
S
L
Y
P
D
A
A
H
G
S
F
Y
Q
Y
P
E
L
F
V
S
Q
T
E
Y
F
L
D
S
Y
124
HHSearch
50.95
21%
-1
- C1 -
2XUA
-
?
A:
[8-264]
-------
A
V
N
G
T
E
L
H
Y
R
I
D
G
E
R
H
G
N
A
P
W
I
V
L
S
N
S
L
G
T
D
L
-
S
M
W
-
A
P
Q
V
A
-
A
L
S
K
----
H
F
-
R
V
L
R
Y
D
T
R
G
H
G
H
S
E
A
P
K
--
G
P
Y
T
I
E
Q
L
T
G
D
V
L
G
L
M
D
T
L
K
I
-
A
-
R
A
N
-------
F
C
G
L
S
M
G
G
L
T
G
V
A
L
A
A
R
H
A
D
R
I
E
R
V
A
L
C
N
T
A
A
R
I
G
S
P
E
-
V
W
V
--
P
R
A
V
K
A
--
R
T
E
G
-
M
H
A
----
L
A
D
A
V
L
--------
P
R
W
F
T
A
D
Y
M
---
E
--
R
E
P
V
V
L
-
A
M
I
R
D
V
---
F
V
H
T
D
K
E
G
Y
A
S
N
C
E
--
A
I
------
D
A
A
D
L
----
R
-
P
-
E
A
P
G
I
K
V
P
A
L
V
I
S
G
T
H
D
L
A
A
T
P
A
Q
G
-
R
E
----
L
A
Q
A
I
A
G
A
R
Y
V
E
L
-
D
A
S
H
I
S
N
I
E
R
A
D
A
F
T
K
T
V
V
D
F
L
T
E
-
122
HHSearch
49.18
21%
-11
- C1 -
3G9X
3
DHAA_RHOSO
A:
[18-292]
---------
L
G
E
R
M
H
Y
V
D
V
G
P
R
--
D
G
T
P
V
L
F
L
H
G
N
P
T
S
S
-
Y
L
W
-
R
N
I
I
P
-
H
V
A
P
----
S
H
-
R
C
I
A
P
D
L
I
G
M
G
K
S
D
K
P
D
--
L
D
Y
F
F
D
D
H
V
R
Y
L
D
A
F
I
E
A
L
G
L
-
E
-
E
V
V
-------
L
V
I
H
D
W
G
S
A
L
G
F
H
W
A
K
R
N
P
E
R
V
K
G
I
A
C
M
E
F
I
R
P
F
P
T
W
D
E
W
P
E
--
F
A
R
E
T
F
Q
A
F
R
T
A
D
V
G
R
E
L
II
D
Q
N
A
F
I
--------
E
G
A
L
P
K
C
V
V
R
P
L
T
E
V
E
M
D
H
Y
R
E
P
F
L
K
-
P
---
V
D
R
E
P
L
W
R
F
P
N
E
L
P
IA
G
E
P
A
N
I
V
A
L
V
E
A
Y
----
M
-
N
-
W
L
H
Q
S
P
V
P
K
L
L
F
W
G
T
P
G
V
L
I
P
P
A
E
A
-
A
R
----
L
A
E
S
L
P
N
C
K
T
V
D
I
G
P
G
L
H
Y
L
Q
E
D
N
P
D
L
I
G
S
E
I
A
R
W
L
P
A
-
114
HHSearch
48.33
19%
-1
- C1 -
4INZ
2
?
A:
[25-304]
--------
V
N
G
V
N
L
H
Y
I
S
K
G
----
Q
G
E
L
M
L
F
L
H
G
F
P
D
F
S
-
H
I
W
-
R
H
Q
I
D
-
E
F
S
N
----
D
F
-
H
T
V
A
L
D
L
R
G
Y
N
L
S
E
K
P
S
G
L
E
S
Y
E
I
D
V
L
V
E
D
I
R
Q
V
I
E
G
L
G
Y
-
S
-
S
C
T
-------
L
V
V
H
D
W
G
A
G
I
G
W
T
F
A
Y
R
Y
P
E
Y
V
Q
K
L
I
A
F
N
G
P
H
P
Y
T
F
M
R
-
E
L
R
TN
K
N
Q
Q
K
A
S
E
Y
A
K
W
-
F
Q
K
Q
---
E
V
Q
D
Y
M
E
RDNF
S
G
L
R
K
L
V
I
D
P
G
V
K
K
G
Y
--
L
T
A
D
D
V
Q
A
Y
M
N
-
S
---
W
E
N
G
S
V
L
S
M
L
S
Y
Y
R
--
N
L
---
K
I
F
T
E
E
D
L
R
RKS
L
F
P
L
E
E
E
V
L
N
I
P
V
Q
I
I
W
G
N
Q
D
P
T
F
M
P
E
N
L
-
D
G
----
I
E
E
Y
V
P
N
I
S
V
H
R
L
A
E
A
S
H
A
P
Q
H
E
K
P
Q
E
V
N
N
V
M
W
N
F
L
N
K
-