@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu30850: (2016-07-21 )
MIKKAIIPAGGFGTRNLPVTKVIPKEMFPVGSKPVIHYLVEELKESGIEDILMVVSSHKNLIVDYFDSSLALEAFLASKNKLHLLREHPIPDIRIHYVRQPYAKGLGDAISFGKQFAGGEPFAVVLPDDLIFSANQPALGQLIEAYTKYQSSVIGLKETKTEDLHHYGVIKGEPVEKGLYRIQDIVEKPKQNPPSHFAAAGRYIFTPDIFNELEALEADSGGEVQVTDAIKASLGACTVYGKLLEGERYDIGLQKDYLKLIYDMLKTEKNPQ
Atome Classification :
(21 SA)
.........10........20........30........40........50........60........70........80--.---.....--..---.-90........100.......110......--.120-........130......-.-.140.......150.......160.......--170....--...180.......190-........200.......210.......220.......230...-....240-...--....--250.......260.......270----------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MIK
K
A
IIPAGGFGTRNLP
V
T
KVI
P
K
E
MFPVGS
K
P
V
I
H
Y
L
V
E
E
L
K
ES
G
I
E
D
I
L
M
V
V
SSHK
N
L
I
V
DYFDS
S
L
A
L
E
A
F
L
ASK
N
---
K
---
L
H
L
L
R
--EH---P-IP
D
I
R
I
H
Y
VR
Q
P
Y
A
KGL
G
D
A
I
S
F
G
K
Q
FAG--GE
P
--
F
A
V
VLPDDLI-FSANQ
P
-
A
-
L
G
Q
L
I
E
A
Y
T
K
Y
Q
S
SVIGLKETKTEDLHHYGV--IKGE
P
V
E
--
K
G
L
Y
R
I
Q
D
I
V
EKPK-Q-NPP
S
H
F
A
AAG
R
Y
I
F
T
P
D
I
F
N
E
L
E
A
LEADSGG
E
V
Q
V
T
D
A
I
K
A
S
L
G
-
A
C
T
V
Y
G
K
-LLE--GERY--DIGL
Q
K
D
Y
L
K
L
I
Y
D
M
L
KTEKNPQ----------------------------------------------
53
HHSearch
73.77
43%
-17
- C1 -
3JUK
4
?
A:
[1-271]
M
I
K
K
C
L
F
P
A
A
G
Y
G
T
R
F
L
P
I
T
K
T
I
P
K
E
M
L
P
I
V
D
K
P
L
I
Q
Y
A
V
E
E
A
M
E
A
G
C
E
V
M
A
I
V
T
G
R
N
K
R
S
L
E
D
Y
F
D
T
S
Y
--------
T
N
---
K
---
E
N
A
L
K
--
S
I
R
--
N
I
I
E
K
C
C
F
S
Y
V
R
Q
K
Q
M
K
G
L
G
H
A
I
L
T
G
E
A
L
I
G
--
N
E
P
--
F
A
V
I
L
A
D
D
L
C
-
I
S
H
D
H
P
S
V
-
L
K
Q
M
T
S
L
Y
Q
K
Y
Q
C
S
I
V
A
I
E
E
V
A
L
E
E
V
S
K
Y
G
V
--
I
R
G
E
W
L
E
--
E
G
V
Y
E
I
K
D
M
V
E
K
P
N
-
Q
E
D
A
P
S
N
L
A
V
I
G
R
Y
I
L
T
P
D
I
F
E
I
L
S
E
T
K
P
G
K
N
N
E
I
Q
I
T
D
A
L
R
T
Q
A
K
-
R
K
R
I
I
A
Y
Q
F
-
K
--
G
K
R
Y
--
D
C
G
S
V
E
G
Y
I
E
A
S
N
A
Y
Y
K
K
---------------------------------------------------
57
HHSearch
73.24
41%
-15
- C1 -
5I1F
9
?
A:
[12-281]
-
V
T
K
A
V
F
P
V
A
G
L
G
T
R
F
L
P
A
T
K
A
S
P
K
E
M
L
P
V
V
D
K
P
L
I
Q
Y
A
V
E
E
A
I
E
A
G
I
T
E
M
I
F
V
T
G
R
S
K
R
A
I
E
D
H
F
D
K
S
Y
E
I
E
A
E
L
E
A
R
G
---
K
---
E
K
L
L
S
--
L
V
R
S
I
K
-
P
S
H
V
D
C
F
Y
V
R
Q
A
E
A
L
G
L
G
H
A
V
L
C
A
E
K
L
V
G
--
D
N
P
--
F
A
V
I
L
A
D
D
L
L
-
D
G
P
-
T
P
-
V
-
L
R
Q
M
I
D
V
F
D
H
Y
H
A
S
V
I
G
V
E
E
I
A
P
A
D
S
K
S
Y
G
V
--
I
D
G
K
R
W
E
--
D
D
L
F
K
L
S
G
I
V
E
K
P
E
-
P
A
Q
A
P
S
N
F
G
V
V
G
R
Y
V
L
K
P
K
I
F
K
H
L
R
G
L
K
P
G
A
G
G
E
L
Q
L
T
D
A
I
Q
S
L
L
T
-
D
E
Q
V
L
A
Y
R
Y
-
D
--
G
T
R
F
--
D
C
G
S
K
L
G
Y
L
K
A
T
V
E
F
A
L
R
H
--------------------------------------------------
1
PsiBlast_PDB
71.65
43%
-10
- C1 -
3JUJ
-
?
A:
[1-263]
M
I
K
K
C
L
F
P
A
A
G
Y
G
T
R
F
L
P
I
T
K
T
I
P
K
E
M
L
P
I
V
D
K
P
L
I
Q
Y
A
V
E
E
A
M
E
A
G
C
E
V
M
A
I
V
T
G
R
N
K
R
S
L
E
D
Y
F
D
T
S
Y
E
I
E
H
Q
I
Q
G
T
N
---
K
---
E
N
A
L
K
S
I
R
N
---
I
-
I
E
K
C
C
F
S
Y
V
R
Q
K
Q
M
K
G
L
G
H
A
I
L
T
G
E
A
L
I
G
--
N
E
P
--
F
A
V
I
L
A
D
D
L
C
-
I
S
H
D
H
P
-
S
V
L
K
Q
M
T
S
L
Y
Q
K
Y
Q
C
S
I
V
A
I
E
E
V
A
L
E
E
V
S
K
Y
G
V
--
I
R
G
E
W
L
E
--
E
G
V
Y
E
I
K
D
M
V
E
K
P
N
-
Q
E
D
A
P
S
N
L
A
V
I
G
R
Y
I
L
T
P
D
I
F
E
I
L
S
E
T
K
P
G
K
N
N
E
I
Q
I
T
D
A
L
R
T
Q
A
K
-
R
K
R
I
I
A
Y
-
Q
F
K
--
G
K
R
Y
--
D
C
G
S
V
E
G
Y
I
E
-----------------------------------------------------------
2
PsiBlast_PDB
71.50
43%
-9
- C1 -
3JUK
4
?
A:
[1-263]
M
I
K
K
C
L
F
P
A
A
G
Y
G
T
R
F
L
P
I
T
K
T
I
P
K
E
M
L
P
I
V
D
K
P
L
I
Q
Y
A
V
E
E
A
M
E
A
G
C
E
V
M
A
I
V
T
G
R
N
K
R
S
L
E
D
Y
F
D
T
S
Y
--------
T
N
---
K
---
E
N
A
L
K
S
I
R
N
---
I
-
I
E
K
C
C
F
S
Y
V
R
Q
K
Q
M
K
G
L
G
H
A
I
L
T
G
E
A
L
I
G
--
N
E
P
--
F
A
V
I
L
A
D
D
L
C
-
I
S
H
D
H
P
-
S
V
L
K
Q
M
T
S
L
Y
Q
K
Y
Q
C
S
I
V
A
I
E
E
V
A
L
E
E
V
S
K
Y
G
V
--
I
R
G
E
W
L
E
--
E
G
V
Y
E
I
K
D
M
V
E
K
P
N
-
Q
E
D
A
P
S
N
L
A
V
I
G
R
Y
I
L
T
P
D
I
F
E
I
L
S
E
T
K
P
G
K
N
N
E
I
Q
I
T
D
A
L
R
T
Q
A
K
-
R
K
R
I
I
A
Y
-
Q
F
K
--
G
K
R
Y
--
D
C
G
S
V
E
G
Y
I
E
-----------------------------------------------------------
3
PsiBlast_PDB
71.41
41%
-6
- C1 -
5I1F
9
?
A:
[12-272]
-
V
T
K
A
V
F
P
V
A
G
L
G
T
R
F
L
P
A
T
K
A
S
P
K
E
M
L
P
V
V
D
K
P
L
I
Q
Y
A
V
E
E
A
I
E
A
G
I
T
E
M
I
F
V
T
G
R
S
K
R
A
I
E
D
H
F
D
K
S
Y
E
I
E
A
E
L
E
A
R
G
---
K
E
K
L
L
S
L
V
R
--
S
I
---
K
-
P
S
H
V
D
C
F
Y
V
R
Q
A
E
A
L
G
L
G
H
A
V
L
C
A
E
K
L
V
G
--
D
N
P
--
F
A
V
I
L
A
D
D
L
L
--
D
G
P
T
P
-
V
-
L
R
Q
M
I
D
V
F
D
H
Y
H
A
S
V
I
G
V
E
E
I
A
P
A
D
S
K
S
Y
G
V
--
I
D
G
K
R
W
E
--
D
D
L
F
K
L
S
G
I
V
E
K
P
E
P
A
-
Q
A
P
S
N
F
G
V
V
G
R
Y
V
L
K
P
K
I
F
K
H
L
R
G
L
K
P
G
A
G
G
E
L
Q
L
T
D
A
I
Q
S
L
L
T
-
D
E
Q
V
L
A
Y
-
R
Y
D
--
G
T
R
F
--
D
C
G
S
K
L
G
Y
L
K
-----------------------------------------------------------
21
PsiBlast_CBE
69.75
43%
-6
- C1 -
3JUK
4
?
D:
[1-263]
M
I
K
K
C
L
F
P
A
A
G
Y
G
T
R
F
L
P
I
T
K
T
I
P
K
E
M
L
P
I
V
D
K
P
L
I
Q
Y
A
V
E
E
A
M
E
A
G
C
E
V
M
A
I
V
T
G
R
N
K
R
S
L
E
D
Y
F
D
T
S
Y
--------
T
N
---
K
---
E
N
A
L
K
SI
R
N
---
I
-
I
E
K
C
C
F
S
Y
V
R
Q
K
Q
M
K
G
L
G
H
A
I
L
T
G
E
A
L
I
G
--
N
E
P
--
F
A
V
I
L
A
D
D
L
C
-
I
S
H
D
H
P
-
S
V
L
K
Q
M
T
S
L
Y
Q
K
Y
Q
C
S
I
V
A
I
E
E
V
A
L
E
E
V
S
K
Y
G
V
--
I
R
G
E
W
L
E
--
E
G
V
Y
E
I
K
D
M
V
E
K
P
N
-
Q
E
D
A
P
S
N
L
A
V
I
G
R
Y
I
L
T
P
D
I
F
E
I
L
S
E
T
K
P
G
K
N
N
E
I
Q
I
T
D
A
L
R
T
Q
A
K
-
R
K
R
I
I
A
Y
-
Q
F
K
--
G
K
R
Y
--
D
C
G
S
V
E
G
Y
I
E
-----------------------------------------------------------
23
PsiBlast_CBE
69.71
43%
-7
- C1 -
3JUK
4
?
B:
[1-263]
M
I
K
K
C
L
F
P
A
A
G
Y
G
T
R
F
L
P
I
T
K
T
I
P
K
E
M
L
P
I
V
D
K
P
L
I
Q
Y
A
V
E
E
A
M
E
A
G
C
E
V
M
A
I
V
T
G
R
N
K
R
S
L
E
D
Y
F
D
T
S
Y
---------
N
---
K
---
E
N
A
L
K
S
I
R
N
---
I
-
I
E
K
C
C
F
S
Y
V
R
Q
K
Q
M
K
G
L
G
H
A
I
L
T
G
E
A
L
I
G
--
N
E
P
--
F
A
V
I
L
A
D
D
L
C
-
I
S
H
D
H
P
-
S
V
L
K
Q
M
T
S
L
Y
Q
K
Y
Q
C
S
I
V
A
I
E
E
V
A
L
E
E
V
S
K
Y
G
V
--
I
R
G
E
W
L
E
--
E
G
V
Y
E
I
K
D
M
V
E
K
P
N
-
Q
E
D
A
P
S
N
L
A
V
I
G
R
Y
I
L
T
P
D
I
F
E
I
L
S
E
T
K
P
G
K
N
N
E
I
Q
I
T
D
A
L
R
T
Q
A
K
-
R
K
R
I
I
A
Y
-
Q
F
K
--
G
K
R
Y
--
D
C
G
S
V
E
G
Y
I
E
-----------------------------------------------------------
22
PsiBlast_CBE
69.66
43%
-9
- C1 -
3JUK
4
?
C:
[1-263]
M
I
K
K
C
L
F
P
A
A
G
Y
G
T
R
F
L
P
I
T
K
T
I
P
K
E
M
L
P
I
V
D
K
P
L
I
Q
Y
A
V
E
E
A
M
E
A
G
C
E
V
M
A
I
V
T
G
R
N
K
R
S
L
E
D
Y
F
D
T
S
Y
---------
N
---
K
---
E
N
A
L
K
SI
R
N
---
I
-
I
E
K
C
C
F
S
Y
V
R
Q
K
Q
M
K
G
L
G
H
A
I
L
T
G
E
A
L
I
G
--
N
E
P
--
F
A
V
I
L
A
D
D
L
C
-
I
S
H
D
H
P
-
S
V
L
K
Q
M
T
S
L
Y
Q
K
Y
Q
C
S
I
V
A
I
E
E
V
A
L
E
E
V
S
K
Y
G
V
--
I
R
G
E
W
L
E
--
E
G
V
Y
E
I
K
D
M
V
E
K
P
N
-
Q
E
D
A
P
S
N
L
A
V
I
G
R
Y
I
L
T
P
D
I
F
E
I
L
S
E
T
K
P
G
K
N
N
E
I
Q
I
T
D
A
L
R
T
Q
A
K
-
R
K
R
I
I
A
Y
-
Q
F
K
--
G
K
R
Y
--
D
C
G
S
V
E
G
Y
I
E
-----------------------------------------------------------
27
PsiBlast_CBE
66.67
37%
-23
- C1 -
2UX8
1
?
E:
[14-272]
-
L
R
K
A
V
F
P
V
A
G
L
G
T
R
F
L
P
A
T
K
A
M
P
K
E
M
L
P
V
V
D
R
P
L
I
Q
Y
A
V
D
E
A
V
E
A
G
I
E
Q
M
I
F
V
T
G
R
G
K
S
A
L
E
D
H
F
D
I
A
Y
E
L
E
A
T
M
A
A
R
G
---
K
S--
L
D
V
L
D
--
G
T
---
R
-
L
K
P
G
N
I
A
Y
V
R
Q
Q
E
P
M
G
L
G
H
A
V
W
C
A
R
D
I
V
G
--
D
E
P
--
F
A
V
L
L
P
D
D
F
M
-
F
--
G
Q
P
G
C
-
L
K
Q
M
V
D
A
Y
N
K
V
G
G
N
L
I
C
A
E
E
V
P
D
D
Q
T
H
R
Y
G
I
--
I
T
P
G
T
Q
D
--
G
V
L
T
E
V
K
G
L
V
E
K
P
A
P
G
-
T
A
P
S
N
L
S
V
I
G
R
Y
I
L
Q
P
E
V
M
R
I
L
E
N
Q
--------
Q
L
T
D
A
M
Q
R
M
I
G
-
D
Q
P
F
H
G
V
-
T
F
Q
--
G
T
R
Y
--
D
C
G
D
K
A
G
F
I
Q
-----------------------------------------------------------
29
PsiBlast_CBE
65.46
37%
-21
- C1 -
2UX8
1
?
C:
[14-272]
-
L
R
K
A
V
F
P
V
A
G
L
G
T
R
F
L
P
A
T
K
A
M
P
K
E
M
L
P
V
V
D
R
P
L
I
Q
Y
A
V
D
E
A
V
E
A
G
I
E
Q
M
I
F
V
T
G
R
G
K
S
A
L
E
D
H
F
D
I
A
Y
E
L
E
A
T
M
A
A
R
G
---
K
S--
L
D
V
L
D
--
G
T
---
R
-
L
K
P
G
N
I
A
Y
V
R
Q
Q
E
P
M
G
L
G
H
A
V
W
C
A
R
D
I
V
G
--
D
E
P
--
F
A
V
L
L
P
D
D
F
M
-
F
--
G
Q
P
G
C
-
L
K
Q
M
V
D
A
Y
N
K
V
G
G
N
L
I
C
A
E
E
V
P
D
D
Q
T
H
R
Y
G
I
--
I
T
P
G
T
Q
D
--
G
V
L
T
E
V
K
G
L
V
E
K
P
A
P
G
-
T
A
P
S
N
L
S
V
I
G
R
Y
I
L
Q
P
E
V
M
R
I
L
E
N
Q
G
-------
Q
L
T
D
A
M
Q
R
M
I
G
-
D
Q
P
F
H
G
V
-
T
F
Q
--
G
T
R
Y
--
D
C
G
D
K
A
G
F
I
Q
-----------------------------------------------------------
25
PsiBlast_CBE
65.19
37%
-17
* C1 *
2UX8
1
?
G:
[14-272]
-
L
R
K
A
V
F
P
V
A
G
L
G
T
R
F
L
P
A
T
K
A
M
P
K
E
M
L
P
V
V
D
R
P
L
I
Q
Y
A
V
D
E
A
V
E
A
G
I
E
Q
M
I
F
V
T
G
R
G
K
S
A
L
E
D
H
F
D
I
A
Y
E
L
E
A
T
M
A
A
R
G
---
K
S--
L
D
V
L
D
--
G
T
---
R
-
L
K
P
G
N
I
A
Y
V
R
Q
Q
E
P
M
G
L
G
H
A
V
W
C
A
R
D
I
V
G
--
D
E
P
--
F
A
V
L
L
P
D
D
F
M
-
F
--
G
Q
P
G
C
-
L
K
Q
M
V
D
A
Y
N
K
V
G
G
N
L
I
C
A
E
E
V
P
D
D
Q
T
H
R
Y
G
I
--
I
T
P
G
T
Q
D
--
G
V
L
T
E
V
K
G
L
V
E
K
P
A
P
G
-
T
A
P
S
N
L
S
V
I
G
R
Y
I
L
Q
P
E
V
M
R
I
L
E
N
Q
G
K
G
A
G
G
E
I
Q
L
T
D
A
M
Q
R
M
I
G
-
D
Q
P
F
H
G
V
-
T
F
Q
--
G
T
R
Y
--
D
C
G
D
K
A
G
F
I
Q
-----------------------------------------------------------
26
PsiBlast_CBE
64.71
37%
-21
- C1 -
2UX8
1
?
F:
[14-272]
-
L
R
K
A
V
F
P
V
A
G
L
G
T
R
F
L
P
A
T
K
A
M
P
K
E
M
L
P
V
V
D
R
P
L
I
Q
Y
A
V
D
E
A
V
E
A
G
I
E
Q
M
I
F
V
T
G
R
G
K
S
A
L
E
D
H
F
D
I
A
Y
E
L
E
A
T
M
A
A
R
G
---
K
S--
L
D
V
L
D
--
G
T
---
R
-
L
K
P
G
N
I
A
Y
V
R
Q
Q
E
P
M
G
L
G
H
A
V
W
C
A
R
D
I
V
G
--
D
E
P
--
F
A
V
L
L
P
D
D
F
M
-
F
--
G
Q
P
G
C
-
L
K
Q
M
V
D
A
Y
N
K
V
G
G
N
L
I
C
A
E
E
V
P
D
D
Q
T
H
R
Y
G
I
--
I
T
P
G
T
Q
D
--
G
V
L
T
E
V
K
G
L
V
E
K
P
A
P
G
-
T
A
P
S
N
L
S
V
I
G
R
Y
I
L
Q
P
E
V
M
R
I
L
E
N
Q
G
K
------
Q
L
T
D
A
M
Q
R
M
I
G
-
D
Q
P
F
H
G
V
-
T
F
Q
--
G
T
R
Y
--
D
C
G
D
K
A
G
F
I
Q
-----------------------------------------------------------
30
PsiBlast_CBE
64.44
37%
-25
- C1 -
2UX8
1
?
B:
[14-272]
-
L
R
K
A
V
F
P
V
A
G
L
G
T
R
F
L
P
A
T
K
A
M
P
K
E
M
L
P
V
V
D
R
P
L
I
Q
Y
A
V
D
E
A
V
E
A
G
I
E
Q
M
I
F
V
T
G
R
G
K
S
A
L
E
D
H
F
D
I
A
Y
E
L
E
A
T
M
A
A
R
G
---
K
S--
L
D
V
L
D
--
G
T
---
R
-
L
K
P
G
N
I
A
Y
V
R
Q
Q
E
P
M
G
L
G
H
A
V
W
C
A
R
D
I
V
G
--
D
E
P
--
F
A
V
L
L
P
D
D
F
M
-
F
--
G
Q
P
G
C
-
L
K
Q
M
V
D
A
Y
N
K
V
G
G
N
L
I
C
A
E
E
V
P
D
D
Q
T
H
R
Y
G
I
--
I
T
P
G
T
Q
D
--
G
V
L
T
E
V
K
G
L
V
E
K
P
A
P
G
-
T
A
P
S
N
L
S
V
I
G
R
Y
I
L
Q
P
E
V
M
R
I
L
E
N
Q
G
--------
L
T
D
A
M
Q
R
M
I
G
-
D
Q
P
F
H
G
V
-
T
F
Q
--
G
T
R
Y
--
D
C
G
D
K
A
G
F
I
Q
-----------------------------------------------------------
28
PsiBlast_CBE
64.33
37%
-21
- C1 -
2UX8
1
?
D:
[14-272]
-
L
R
K
A
V
F
P
V
A
G
L
G
T
R
F
L
P
A
T
K
A
M
P
K
E
M
L
P
V
V
D
R
P
L
I
Q
Y
A
V
D
E
A
V
E
A
G
I
E
Q
M
I
F
V
T
G
R
G
K
S
A
L
E
D
H
F
D
I
A
Y
E
L
E
A
T
M
A
A
R
G
---
K
S--
L
D
V
L
D
--
G
T
---
R
-
L
K
P
G
N
I
A
Y
V
R
Q
Q
E
P
M
G
L
G
H
A
V
W
C
A
R
D
I
V
G
--
D
E
P
--
F
A
V
L
L
P
D
D
F
M
-
F
--
G
Q
P
G
C
-
L
K
Q
M
V
D
A
Y
N
K
V
G
G
N
L
I
C
A
E
E
V
P
D
D
Q
T
H
R
Y
G
I
--
I
T
P
G
T
Q
D
--
G
V
L
T
E
V
K
G
L
V
E
K
P
A
P
G
-
T
A
P
S
N
L
S
V
I
G
R
Y
I
L
Q
P
E
V
M
R
I
L
E
N
Q
G
-------
Q
L
T
D
A
M
Q
R
M
I
G
-
D
Q
P
F
H
G
V
-
T
F
Q
--
G
T
R
Y
--
D
C
G
D
K
A
G
F
I
Q
-----------------------------------------------------------
13
PsiBlast_PDB
62.11
28%
-116
- C1 -
4HO3
4
?
A:
[2-215]
---
K
G
I
I
L
S
G
G
S
G
T
R
L
Y
P
L
T
K
V
V
S
K
Q
L
L
P
V
Y
D
K
P
M
V
Y
Y
P
L
S
V
L
M
L
A
G
I
K
D
I
L
I
I
S
T
P
---------
E
D
T
P
R
F
E
Q
L
L
G
G
G
S
---
E
---
L
---------------
G
I
S
L
S
Y
A
V
Q
S
S
P
D
G
L
A
Q
A
F
I
I
G
E
E
F
I
G
--
D
D
N
--
V
A
L
V
L
G
D
N
I
F
-
Y
G
H
G
F
T
-
E
-
L
L
Q
R
-
A
A
N
R
K
S
G
A
T
I
F
G
Y
---
N
V
K
D
P
Q
R
F
G
V
--
V
E
F
D
--
E
--
K
G
--
K
V
I
S
I
E
E
K
P
E
-
E
--
P
K
S
S
Y
A
V
T
G
L
Y
F
Y
D
N
R
V
V
D
I
A
K
N
I
T
P
S
A
R
G
E
L
E
I
T
D
V
N
K
A
Y
L
E
-
L
G
E
L
H
V
E
-
L
L
------------------------------------------------------------------------------
12
PsiBlast_PDB
61.92
28%
-115
- C1 -
4HO2
5
?
A:
[2-215]
---
K
G
I
I
L
S
G
G
S
G
T
R
L
Y
P
L
T
K
V
V
S
K
Q
L
L
P
V
Y
D
K
P
M
V
Y
Y
P
L
S
V
L
M
L
A
G
I
K
D
I
L
I
I
S
T
P
---------
E
D
T
P
R
F
E
Q
L
L
G
G
G
S
---
E
---
L
---------------
G
I
S
L
S
Y
A
V
Q
S
S
P
D
G
L
A
Q
A
F
I
I
G
E
E
F
I
G
--
D
D
N
--
V
A
L
V
L
G
D
N
I
F
-
Y
G
H
G
F
T
-
E
-
L
L
Q
R
-
A
A
N
R
K
S
G
A
T
I
F
G
Y
---
N
V
K
D
P
Q
R
F
G
V
--
V
E
F
D
--
E
--
K
G
--
K
V
I
S
I
E
E
K
P
E
-
E
--
P
K
S
S
Y
A
V
T
G
L
Y
F
Y
D
N
R
V
V
D
I
A
K
N
I
T
P
S
A
R
G
E
L
E
I
T
D
V
N
K
A
Y
L
E
-
L
G
E
L
H
V
E
-
L
L
------------------------------------------------------------------------------
4
PsiBlast_PDB
61.88
29%
-14
- C1 -
2PA4
2
?
A:
[12-279]
-
V
K
T
V
V
V
P
A
A
G
L
G
T
R
F
L
P
A
T
K
T
V
P
K
E
L
L
P
V
V
D
T
P
G
I
E
L
I
A
A
E
A
A
E
L
G
A
T
R
L
A
I
I
T
A
P
N
K
A
G
V
L
A
H
F
E
R
S
S
E
L
E
E
T
L
M
E
R
G
---
K
T
D
Q
V
E
I
I
R
---
R
---
A
-
A
D
L
I
K
A
V
P
V
T
Q
D
K
P
L
G
L
G
H
A
V
G
L
A
E
S
V
L
D
--
D
D
E
D
V
V
A
V
M
L
P
D
D
L
V
-
L
P
T
G
---
V
-
M
E
R
M
A
Q
V
R
A
E
F
G
G
S
V
L
C
A
V
E
V
S
E
A
D
V
S
K
Y
G
I
F
E
I
E
A
D
T
K
D
--
S
D
V
K
K
V
K
G
M
V
E
K
P
A
I
E
-
D
A
P
S
R
L
A
A
T
G
R
Y
L
L
D
R
K
I
F
D
A
L
R
R
I
T
P
G
A
G
G
E
L
Q
L
T
D
A
I
D
L
L
I
D
E
G
H
P
V
H
I
V
-
I
H
Q
--
G
K
R
H
--
D
L
G
N
P
G
G
Y
I
P
A
C
V
D
-------------------------------------------------------
41
Fugue
61.01
26%
-90
- C1 -
1FXO
2
?
A:
[2-293]
-
K
R
K
G
I
I
L
A
G
G
S
G
T
R
L
H
P
A
T
L
A
I
S
K
Q
L
L
P
V
Y
D
K
P
M
I
Y
Y
P
L
S
T
L
M
L
A
G
I
R
E
I
L
I
I
S
T
P
---------
Q
D
T
P
R
F
Q
Q
L
L
G
D
G
S
---
N
---
W
---------------
G
L
D
L
Q
Y
A
V
Q
P
S
P
D
G
L
A
Q
A
F
L
I
G
E
S
F
I
G
--
N
D
L
--
S
A
L
V
L
G
D
N
L
Y
-
Y
G
H
D
---
F
-
H
E
L
L
G
S
A
S
Q
R
Q
T
G
A
S
V
F
A
Y
H
V
L
--
D
P
E
R
Y
G
V
--
V
E
F
D
Q
G
G
--
K
----
A
I
S
L
E
E
K
P
L
---
E
P
K
S
N
Y
A
V
T
G
L
Y
F
Y
D
Q
Q
V
V
D
I
A
R
D
L
K
P
S
P
R
G
E
L
E
I
T
D
V
N
R
A
Y
L
E
-
R
G
Q
L
S
V
E
-
I
M
G
RG
Y
A
W
L
--
D
T
G
T
H
D
S
L
L
E
A
G
Q
F
I
A
T
L
E
N
R
Q
G
LKVAC
P
E
E
I
A
Y
R
Q
KWID
A
A
Q
L
E
K
L
A
A
P
L
AKN
G
Y
G
Q
Y
L
K
R
L
L
T
ETVY
18
PsiBlast_PDB
60.68
28%
-113
- C1 -
4HO9
7
?
A:
[2-215]
---
K
G
I
I
L
S
G
G
S
G
T
R
L
Y
P
L
T
K
V
V
S
K
Q
L
L
P
V
Y
D
K
P
M
V
Y
Y
P
L
S
V
L
M
L
A
G
I
K
D
I
L
I
I
S
T
P
---------
E
D
T
P
R
F
E
Q
L
L
G
G
G
S
---
E
---
L
---------------
G
I
S
L
S
Y
A
V
Q
S
S
P
D
G
L
A
Q
A
F
I
I
G
E
E
F
I
G
--
D
D
N
--
V
A
L
V
L
G
D
N
I
F
-
Y
G
H
G
F
T
-
E
-
L
L
Q
R
-
A
A
N
R
K
S
G
A
T
I
F
G
Y
---
N
V
K
D
P
Q
R
F
G
V
--
V
E
F
D
--
E
--
K
G
--
K
V
I
S
I
E
E
K
P
E
-
E
--
P
K
S
S
Y
A
V
T
G
L
Y
F
Y
D
N
R
V
V
D
I
A
K
N
I
T
P
S
A
R
G
E
L
E
I
T
D
V
N
K
A
Y
L
E
-
L
G
E
L
H
V
E
-
L
L
------------------------------------------------------------------------------
52
HHSearch
60.52
30%
-8
- C1 -
2PA4
2
?
A:
[12-282]
-
V
K
T
V
V
V
P
A
A
G
L
G
T
R
F
L
P
A
T
K
T
V
P
K
E
L
L
P
V
V
D
T
P
G
I
E
L
I
A
A
E
A
A
E
L
G
A
T
R
L
A
I
I
T
A
P
N
K
A
G
V
L
A
H
F
E
R
S
S
E
L
E
E
T
L
M
E
R
G
K
T
D
Q
---
V
E
I
I
R
--
R
A
-----
A
D
L
I
K
A
V
P
V
T
Q
D
K
P
L
G
L
G
H
A
V
G
L
A
E
S
V
L
D
DD
E
D
V
--
V
A
V
M
L
P
D
D
L
V
L
P
T
G
-
V
----
M
E
R
M
A
Q
V
R
A
E
F
G
G
S
V
L
C
A
V
E
V
S
E
A
D
V
S
K
Y
G
I
--
F
E
I
E
A
D
T
KD
S
D
V
K
K
V
K
G
M
V
E
K
P
A
-
I
E
D
A
P
S
R
L
A
A
T
G
R
Y
L
L
D
R
K
I
F
D
A
L
R
R
I
T
P
G
A
G
G
E
L
Q
L
T
D
A
I
D
L
L
I
D
E
G
H
P
V
H
I
V
I
H
-
Q
--
G
K
R
H
--
D
L
G
N
P
G
G
Y
I
P
A
C
V
D
F
G
L
----------------------------------------------------
10
PsiBlast_PDB
56.71
32%
-114
- C1 -
2GGQ
2
?
A:
[2-210]
---
K
A
F
I
L
A
A
G
S
G
E
R
L
E
P
I
T
H
T
R
P
K
A
F
V
P
I
L
S
K
P
L
I
E
Y
Q
I
E
Y
L
R
K
C
G
I
R
D
I
T
V
I
V
S
S
K
N
K
---
E
Y
F
E
K
K
L
K
E
I
S
I
V
T
Q
K
D
---
D
---
I
---------------------------
K
G
T
G
A
A
I
-
L
S
A
K
F
-----
N
D
--
E
A
L
I
I
Y
G
D
L
F
-
F
S
-
N
E
K
-
E
-
I
C
N
I
I
---
T
L
K
E
N
A
I
I
G
V
K
V
S
N
P
K
D
---
Y
G
V
--
L
----
V
L
--
D
N
Q
N
N
L
S
K
I
I
E
K
P
--
E
-
I
P
P
S
N
L
I
N
A
G
I
Y
K
L
N
S
D
I
F
T
Y
L
D
K
I
S
I
S
E
R
G
E
L
E
L
T
D
A
I
--
N
L
M
-
A
K
D
H
R
V
K
-
V
I
E
--
Y
E
G
Y
W
M
D
I
G
------------------------------------------------------------------