@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu31240: (2016-07-22 )
MKKILQLIKQRSITRKLLVSFLSILIIPVVILAIFAYQSASSSLDRQMMGSALENVQQLNEIINTSIGEKENSADYFSEWLTKEKYNAKSNASIAEKFSQYISINKDVESIYTSDTKGHFTRYPDLPMPSGYNPVERDWYKKAVANKGKVVITDPYKTASTNTMVVTIAQQTKDGSGVIAINMTIENLLKTTKKVNIGTQGYAFIMTKDKKVVAHPNEQSGTELKGDWLDKMLSADKGDFQYTMDGDKKKMAFDTNKLTGWKIGGTMYLDEIHEAAQPVLHLALIVLAAAIIIGIIVMTLIIRSITTPLKQLVGSSKRISEGDLTETIDIRSKDELGELGKSFNNMASSLRSLIHAIQDSVDNVAASSEELTASAAQTSKATEHITLAIEQFSNGNEKQNENIETAAEHIYQMNDGLTNMAQASEVITDSSVQSTEIASEGGKLVHQTVGQMNVIDKSVKEAEQVVRGLETKSKDITNILRVINGIADQTNLLALNAAIEAARAGEYGRGFSVVAEEVRKLAVQSADSAKEIEGLIIEIVKEINTSLGMFQSVNQEVQTGLDITDKTEMSFKRISEMTNQIAGELQNMSATVQQLSASSEEVSGASEHIASISKESSAHIQDIAASAEEQLASMEEISSSAETLSSMAEELRDMTKRFKIE
Atome Classification :
(20 SA)
.........10........20..--......30--------------.........40........50-.....-...60........70........80...-....-.90........100.....-------------------..---110......-.-----------120.--.....----.130......--------.140.....-..-150-------.......160.......170..----.----.-----..------.180.......190..--.....200.......210-------....-....220..-.-.--------.--...230..-......---240-.--.--......250.......260.......270.......280......---------.290.......300.......310.......--------320.......330..-.....-.340.......350-........360.......370.-----......------380.......390.......400.....--..410.......420-----........430.......440.......450.......460.......470.......480.......490....-------...500.......510.......520-------........530.......540.......550-.......560.......-------570....-...580.......590.......600.......610.......620..-.....630.......640.....----..650.......660--------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
K
K
I
L
Q
L
I
K
QR
S
I
T
R
K
L
L
V
S
F
L
S
--
I
L
I
I
P
V
V
---------------
I
L
A
I
F
A
YQSA
S
S
S
L
D
R
Q
M
M
G
S
-
A
L
E
N
V
-
Q
Q
L
N
E
I
I
N
T
SIGEKEN
S
A
D
Y
F
S
E
W
L
T
K
E-KYNA-KSN
A
S
I
A
E
K
F
S
Q
Y
I
SINK
D
-------------------
V
E
---
S
I
YTSDTKG-H-----------FTRY--PDLPM----PSGYNP
V
E
R
D
--------
W
Y
K
K
A
VANK-G
K
-
V
V
I
-------TDPYKTAST
N
T
M
V
V
T
I
AQQTKD----G----
S
-----
G
V
------
I
A
I
N
M
T
I
E
N
L
L
K
T
T
KK--VNIGTQ
G
Y
A
F
I
M
TKD
K
K
--------
V
V
AH-PNEQS-GTE-L-
K
--------
G
--
D
W
L
D
K
-
M
L
-SADKG
D
---
F
Q
--
Y
--T--MDGDK
K
K
M
A
FDTNKL
T
G
W
K
IG
G
T
M
Y
L
D
E
I
H
E
A
A
Q
P
V
L
H
L
A
L
I
V
L
A
---------
A
A
I
I
I
G
I
I
V
M
T
L
I
I
R
S
I
T
T
P
L
K
Q
L
VGSSKRI--------SEGDL
T
E
T
IDI-R
S
K
-
D
E
L
G
E
-
L
G
K
S
F
N
N
M
A
S
S
L
R
--
S
L
I
H
A
I
Q
D
S
V
D
N
VAAS
S
E
E
L
T
A
-----
S
AAQTS------KAT
E
H
I
T
L
A
I
EQFSNGNEKQNE
N
I
E
T
A
A
--
E
H
I
Y
Q
MNDGL
T
N
M
A
------
Q
A
S
E
VITDSSVQS
T
E
I
A
SEG
G
K
L
V
H
Q
T
VGQ
M
N
V
I
D
K
S
V
K
E
A
E
Q
V
V
R
GLETK
S
K
D
I
T
N
I
L
R
V
I
N
GIADQT
N
L
L
A
L
N
-------
A
A
I
E
A
A
RAGEYGR
G
F
S
V
V
A
E
E
V
R
K
L
--------
A
VQSAD
S
A
K
E
I
E
G
L
I
I
E
I
V
K
E
I
N
T
SL
G
M
F
Q
S
-
V
N
Q
E
V
Q
TGLDITD
K
T
E
M
-------
S
F
K
R
I
S
E
-
M
T
N
Q
I
A
G
E
L
Q
N
M
S
A
T
V
Q
Q
L
SASSEEVSG
A
S
E
H
I
A
S
ISKESS
A
H
I
Q
D
I
A
-
A
S
A
E
E
Q
L
A
S
M
E
E
I
S
S
S
A
E
T
L
S
S
M
----
A
E
E
L
R
D
M
T
K
RFKIE---------------------------------------------------------------------
46
Fugue
72.90
28%
-69
- C2 -
2CH7
2
MCP2_THEMA
A:
[1-309]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
--
S
H
M
K
D
V
Q
T
E
T
F
S
V
A
E
S
I
E
E
I
S
K
-----
A
N
E
E
I
T
------
N
Q
L
L
G
I
S
K
E
M
D
N
I
S
T
R
I
E
S
I
S
A
S
V
Q
E
T
T
--
A
G
S
E
E
I
S
S
A
T
K
N
I
A
------
D
S
A
Q
Q
A
A
S
F
A
D
Q
S
T
Q
L
A
K
E
A
G
D
A
L
K
K
V
I
E
V
T
R
M
I
S
N
S
A
K
D
V
E
R
V
V
E
S
F
Q
K
G
A
E
E
I
T
S
F
V
E
T
I
N
A
I
A
E
Q
T
N
L
L
A
L
N
-------
A
A
I
E
A
A
R
A
G
E
A
G
R
G
F
A
V
V
A
D
E
I
R
K
L
--------
A
E
E
S
Q
Q
A
S
E
N
V
R
R
V
V
N
E
I
R
S
I
A
E
D
A
G
K
V
S
S
E
-
I
T
A
R
V
E
E
G
T
K
L
A
D
E
A
D
E
-------
K
L
N
S
I
V
G
-
A
V
E
R
I
N
E
M
L
Q
N
I
A
A
A
I
E
E
Q
T
A
A
V
D
E
I
T
T
A
M
T
E
N
A
K
N
A
E
E
I
T
N
S
V
K
E
V
N
-
A
R
L
Q
E
I
S
A
S
T
E
E
V
T
S
R
V
Q
T
I
R
E
N
----
V
Q
M
L
K
E
I
V
A
R
Y
K
-----------------------------------------------------------------------
21
PsiBlast_CBE
65.15
31%
17
- C2 -
2CH7
2
MCP2_THEMA
B:
[13-309]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
V
A
E
S
I
E
E
I
S
K
A
N
E
E
I
T
N
-----
Q
L
L
G
I
S
------
K
E
M
D
N
I
S
T
R
I
E
S
I
S
A
S
V
Q
------
E
T
T
A
G
S
E
E
I
S
S
A
T
K
N
I
A
D
S
A
------
Q
Q
A
A
S
F
A
D
---
Q
S
T
Q
L
A
K
E
A
G
D
A
L
K
K
V
I
E
V
T
R
M
I
S
N
S
A
K
D
V
E
R
V
V
E
S
F
Q
K
G
A
E
E
I
T
S
F
V
E
T
I
N
A
I
A
E
Q
T
N
L
L
A
L
N
-------
A
A
I
E
A
A
R
A
G
E
A
G
R
G
F
A
V
V
A
D
E
I
R
K
L
--------
A
E
E
S
Q
Q
A
S
E
N
V
R
R
V
V
N
E
I
-
R
S
I
A
E
D
A
G
K
V
S
S
E
I
T
A
R
V
E
E
G
T
K
L
A
D
E
A
D
E
K
L
N
S
I
V
G
A
V
E
R
I
N
E
-
M
L
Q
N
I
A
A
A
I
E
E
Q
N
A
A
V
D
E
I
T
T
A
M
T
E
N
A
K
N
A
E
E
I
T
N
S
V
K
E
V
N
A
R
L
Q
E
I
S
--------
A
S
T
E
E
V
T
S
R
V
Q
T
I
R
E
N
----
V
Q
M
L
K
E
I
V
A
R
Y
K
-----------------------------------------------------------------------
1
PsiBlast_PDB
62.76
31%
10
- C2 -
2CH7
2
MCP2_THEMA
A:
[13-309]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
V
A
E
S
I
E
E
I
S
K
A
N
E
E
I
T
N
-----
Q
L
L
G
I
S
------
K
E
M
D
N
I
S
T
R
I
E
S
I
S
A
S
V
Q
------
E
T
T
A
G
S
E
E
I
S
S
A
T
K
N
I
A
D
S
A
------
Q
Q
A
A
S
F
A
D
---
Q
S
T
Q
L
A
K
E
A
G
D
A
L
K
K
V
I
E
V
T
R
M
I
S
N
S
A
K
D
V
E
R
V
V
E
S
F
Q
K
G
A
E
E
I
T
S
F
V
E
T
I
N
A
I
A
E
Q
T
N
L
L
A
L
N
-------
A
A
I
E
A
A
R
A
G
E
A
G
R
G
F
A
V
V
A
D
E
I
R
K
L
--------
A
E
E
S
Q
Q
A
S
E
N
V
R
R
V
V
N
E
I
-
R
S
I
A
E
D
A
G
K
V
S
S
E
I
T
A
R
V
E
E
G
T
K
L
A
D
E
A
D
E
K
L
N
S
I
V
G
A
V
E
R
I
N
E
-
M
L
Q
N
I
A
A
A
I
E
E
Q
T
A
A
V
D
E
I
T
T
A
M
T
E
N
A
K
N
A
E
E
I
T
N
S
V
K
E
V
N
A
R
L
Q
E
I
S
--------
A
S
T
E
E
V
T
S
R
V
Q
T
I
R
E
N
----
V
Q
M
L
K
E
I
V
A
R
Y
K
-----------------------------------------------------------------------
30
HHSearch
62.62
14%
12
* C3 *
3LIF
2
?
A:
[12-246]
---------------------------------------------------------------
Q
S
E
T
E
-
M
R
N
L
S
-
H
S
L
A
E
H
A
T
H
T
F
Q
G
A
D
V
V
L
D
D
I
V
S
F
M
K
W
R
-
P
H
----
P
S
P
V
F
N
E
R
L
R
A
L
A
D
N
L
P
Q
-------------------
L
S
---
D
V
A
I
L
D
A
D
G
-
Q
-----------
L
T
Y
A
--
S
V
K
P
-----
V
P
A
L
D
N
S
D
R
S
--------
Y
F
R
Y
H
R
A
N
D
D
H
T
-
L
L
I
-------
T
G
P
I
Q
S
R
T
S
G
V
W
V
F
V
V
S
R
R
L
E
T
TDGK
F
----
F
-----
G
V
------
V
V
A
T
I
E
S
E
Y
F
S
T
F
Y
K
T
--
F
D
L
G
P
G
G
S
I
S
L
L
H
S
D
G
R
--------
L
L
I
Q
-
W
P
S
L
Q
-
T
G
R
-
D
M
A
N-------
M
--
V
L
F
Q
K
-
A
L
P
R
S
P
D
G
Y
---
Y
L
T
V
S
--
P
--
F
D
G
L
T
K
Y
L
A
Y
R
R
V
S
R
Y
P
L
V
V
T
V
A
R
T
E
D
S
V
L
S
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
62.33
31%
8
- C2 -
3JA6
-
MCP2_THEMA
G:
[233-529]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
V
A
E
S
I
E
E
I
S
K
A
N
E
E
I
T
N
-----
Q
L
L
G
I
S
------
K
E
M
D
N
I
S
T
R
I
E
S
I
S
A
S
V
Q
------
E
T
T
A
GS
E
E
I
S
S
A
T
K
N
I
A
D
S
A
------
Q
Q
A
A
S
F
A
D
---
Q
S
T
Q
L
A
K
E
A
G
D
A
L
K
K
V
I
E
V
T
R
M
I
S
N
S
A
K
D
V
E
R
V
V
E
S
F
Q
K
G
A
E
E
I
T
S
F
V
E
T
I
N
A
I
A
E
Q
T
N
L
L
A
L
N
-------
A
A
I
E
A
A
R
A
G
E
A
G
R
G
F
A
V
V
A
D
E
I
R
K
L
--------
A
E
E
S
Q
Q
A
S
E
N
V
R
R
V
V
N
E
I
-
R
S
I
A
E
D
A
G
K
V
S
S
E
I
T
A
R
V
E
E
G
T
K
L
A
D
E
A
D
E
KLNSIVG
A
V
E
R
I
N
E
-
M
L
Q
N
I
A
A
A
I
E
E
Q
T
A
A
V
D
E
I
T
T
A
M
T
E
N
A
K
N
A
E
E
I
T
N
S
V
K
E
V
N
A
R
L
Q
E
I
S
--------
A
S
T
E
E
V
T
S
R
V
Q
T
I
R
E
N
----
V
Q
M
L
K
E
I
V
A
R
Y
K
-----------------------------------------------------------------------
26
HHSearch
60.63
32%
-46
- C2 -
2CH7
2
MCP2_THEMA
A:
[93-309]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
L
K
K
V
I
E
V
T
R
M
I
S
N
S
A
K
D
V
E
R
V
V
E
S
F
Q
K
G
A
E
E
I
T
S
F
V
E
T
I
N
A
I
A
E
Q
T
N
L
L
A
L
N
-------
A
A
I
E
A
A
R
A
G
E
A
G
R
G
F
A
V
V
A
D
E
I
R
K
L
--------
A
E
E
S
Q
Q
A
S
E
N
V
R
R
V
V
N
E
I
R
S
I
A
E
D
A
G
K
V
S
S
E
-
I
T
A
R
V
E
E
G
T
K
L
A
D
E
A
D
E
-------
K
L
N
S
I
V
G
-
A
V
E
R
I
N
E
M
L
Q
N
I
A
A
A
I
E
E
Q
T
A
A
V
D
E
I
T
T
A
M
T
E
N
A
K
N
A
E
E
I
T
N
S
V
K
E
V
N
-
A
R
L
Q
E
I
S
A
S
T
E
E
V
T
S
R
V
Q
T
I
R
E
N
----
V
Q
M
L
K
E
I
V
A
R
Y
K
-----------------------------------------------------------------------
47
Fugue
59.56
27%
-55
- C2 -
1QU7
-
MCP1_ECOLI
A:
[294-520]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
T
E
Q
Q
A
A
S
L
E
Q
T
A
------
A
S
M
E
Q
L
T
A
T
V
K
Q
N
A
E
N
A
R
Q
A
S
H
L
A
L
S
A
S
E
T
A
Q
R
G
G
K
V
V
D
N
V
V
Q
T
M
R
D
I
S
T
S
S
Q
K
I
A
D
I
I
S
V
I
D
G
I
A
F
Q
T
N
I
L
A
L
N
-------
A
A
V
E
A
A
R
A
G
E
Q
G
R
G
F
A
V
V
A
G
E
V
R
N
L
--------
A
Q
R
S
A
Q
A
A
R
E
I
K
S
L
I
E
D
S
V
G
K
V
D
V
G
S
T
L
V
E
S
-
A
G
E
T
M
A
E
I
V
S
A
V
T
R
V
T
D
-------
I
M
G
E
I
A
S
-
A
S
D
E
Q
S
R
G
I
D
Q
V
G
L
A
V
A
E
M
D
R
V
T
Q
Q
N
A
A
L
V
E
Q
S
A
A
A
A
A
A
L
E
E
Q
A
S
R
L
T
-
E
A
V
A
V
F
R
I
Q
Q
Q
---------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
58.83
32%
87
- C2 -
3ZX6
2
B:
[3-227]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
T
R
P
I
I
E
L
S
N
T
V
D
K
I
--------
A
E
G
N
L
E
A
E
V
P
H
-
Q
N
R
A
D
E
I
G
I
-
L
A
K
S
I
E
R
L
R
R
S
L
M
--
R
T
V
G
D
V
R
N
G
A
N
A
I
Y
S
G
A
S
E
I
A
T
-----
G
N
N
D
L
S
------
S
R
T
E
Q
Q
A
A
S
L
E
E
T
A
A
S
M
E
Q
L
T
A
T
V
K
Q
N
A
--
E
----------
N
A
R
------
Q
A
S
H
L
----
A
L
S
A
S
E
T
A
Q
R
G
G
K
V
V
D
N
V
V
--------------
Q
T
M
R
D
I
S
T
S
S
Q
K
I
A
D
I
I
S
V
I
D
G
I
A
F
Q
T
N
I
L
A
L
N
-------
A
A
V
E
A
A
R
A
G
E
Q
G
R
G
F
A
V
V
A
G
E
V
R
N
L
--------
A
Q
R
S
A
Q
A
A
R
E
I
K
S
L
I
E
D
S
V
G
K
V
D
V
G
S
T
L
V
E
S
-
A
G
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
Fugue
58.05
14%
63
- C3 -
3LIF
2
?
A:
[4-246]
------------------------------------------------------------
D
S
H
K
I
A
L
A
-
Q
S
E
T
E
M
R
N
L
S
H
S
L
A
E
H
A
T
H
T
F
Q
G
A
D
V
V
L
D
D
I
V
S
F
M
K
W
R
P
-
H
P
S
P
V
F
N
E
R
L
R
A
L
A
D
N
L
P
Q
-------------------
L
S
---
D
V
A
I
L
D
A
D
G
-
Q
-----------
L
T
Y
A
--
S
V
K
P
V
----
P
A
L
-
D
N
S
D
R
S
--------
Y
F
R
Y
H
R
A
N
D
-
D
H
T
L
L
I
-------
T
G
P
I
Q
S
R
T
S
G
V
W
V
F
V
V
S
R
R
L
E
T
----
T
DGKF
F
-----
G
V
------
V
V
A
T
I
E
S
E
Y
F
S
T
F
Y
K
T
--
F
D
L
G
P
G
G
S
I
S
L
L
H
S
D
G
R
--------
L
L
I
Q
W
P
S
L
Q
T
-
G
R
D
M
A
-
N
M-------
V
--
L
F
Q
K
A
-
L
P
-
R
S
P
D
G
Y
---
Y
L
--
T
--
V
S
P
F
D
G
L
T
K
Y
L
A
Y
R
R
V
S
R
Y
P
L
V
V
T
V
A
R
T
E
D
S
V
L
S
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
Fugue
57.88
19%
91
- C3 -
3C8C
2
?
A:
[1-240]
----------------------------------------------------------------
S
L
R
S
M
V
S
D
S
V
-
D
E
I
V
D
G
V
S
K
T
T
A
E
V
I
N
G
R
K
S
I
A
Q
Y
A
T
S
L
-
I
E
N
N
-
P
E
P
D
N
V
R
T
I
I
S
Q
P
L
I
K
N
T
F
-------------------
L
L
---
V
G
F
G
L
E
K
D
G
S
N
-----------
I
N
N
D
--
P
S
W
N
P
----
G
P
T
W
D
P
R
V
R
P
--------
W
Y
K
D
A
K
N
A
--
G
K
-
L
V
I
-------
T
A
P
Y
A
D
S
A
S
G
E
I
L
V
S
V
A
T
P
V
K
D
----
S
----
A
TGQFL
G
S
------
I
F
Y
D
V
S
L
A
E
L
A
E
L
V
N
E
--
V
K
L
F
D
A
G
Y
V
F
I
V
S
E
D
G
T
--------
T
I
A
H
-
P
K
K
E
F
-
N
G
K
-
P
M
S
--------
E
--
F
L
G
E
S
----
K
I
N
V
D
T
---
H
Q
--
V
--
I
--
I
N
G
K
P
Y
A
V
S
F
S
D
V
E
G
E
D
W
Y
V
G
V
V
I
D
E
E
I
A
Y
A
A
L
D
E
L
R
R
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
57.62
32%
111
- C2 -
3ZX6
1
MCP1_ECOLI
A:
[3-227]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
T
R
P
I
I
E
L
S
N
T
V
D
K
I
--------
A
E
G
N
L
E
A
E
V
P
H
-
Q
N
R
A
D
E
I
G
I
-
L
A
K
S
I
E
R
L
R
R
S
L
M
--
R
T
V
G
D
V
R
N
G
A
N
A
I
Y
S
G
A
S
E
I
A
T
-----
G
N
N
D
L
S
------
S
R
T
E
Q
Q
A
A
S
L
E
E
T
A
A
S
M
E
Q
L
T
A
T
V
K
Q
N
A
--
E
----------
N
A
R
------
Q
A
S
H
L
----
A
L
S
A
S
E
T
A
Q
R
G
G
K
V
V
D
N
V
V
--------------
Q
T
M
R
D
I
S
T
S
S
Q
K
I
A
D
I
I
S
V
I
D
G
I
A
F
Q
T
N
I
L
A
L
N
-------
A
A
V
E
A
A
R
A
G
E
Q
G
R
G
F
A
V
V
A
G
E
V
R
N
L
--------
A
Q
R
S
A
Q
A
A
R
E
I
K
S
L
I
E
D
S
V
G
K
V
D
V
G
S
T
L
V
E
S
-
A
G
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
56.83
29%
139
- C2 -
3ZX6
1
MCP1_ECOLI
A:
[3-304]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
T
R
P
I
I
E
L
S
N
T
V
D
K
I
--------
A
E
G
N
L
E
A
E
V
P
H
Q
N
R
A
-
D
E
I
G
I
-
L
A
K
S
I
E
R
L
R
R
S
L
M
--
R
T
V
G
D
V
R
N
G
A
N
A
I
Y
S
G
A
S
E
I
A
T
-----
G
N
N
--------------------
D
L
S
S
R
T
E
Q
Q
A
A
S
L
E
E
T
A
--
A
S
M
E
Q
L
T
A
T
V
K
Q
N
A
------
E
N
A
R
Q
A
S
H
L
A
-------
L
-------
S
A
S
E
T
A
Q
R
G
G
K
V
V
D
N
V
V
Q
T
M
R
D
I
S
T
S
S
Q
K
I
A
D
I
I
S
V
I
D
G
I
A
F
Q
T
N
I
L
A
L
N
-------
A
A
V
E
A
A
R
A
G
E
Q
G
R
G
F
A
V
V
A
G
E
V
R
N
L
--------
A
Q
R
S
A
Q
A
A
R
E
I
K
S
L
I
E
D
S
V
G
K
V
D
V
G
S
T
---------------
L
V
E
--------------
S
A
G
E
-
T
M
A
E
I
V
S
A
V
T
R
V
T
D
I
M
G
E
I
A
S
A
S
D
E
Q
S
R
G
I
D
Q
-------
V
G
L
A
V
A
E
M
D
-
R
V
T
Q
Q
N
A
A
L
V
E
E
S
A
A
A
A
A
A
L
E
E
Q
----
A
S
R
L
T
E
A
V
A
V
F
R
I
----------------------------------------------------------------------
52
Fugue
55.52
14%
44
- C3 -
4XMR
2
?
A:
[1-249]
---------------------------------------------------
G
I
D
P
F
T
K
T
S
L
Y
E
S
T
L
K
N
-
Q
T
D
L
L
-
K
V
T
Q
S
T
V
E
D
F
R
S
T
N
Q
S
F
T
R
A
L
E
K
D
I
A
N
L
-
P
Y
Q
S
L
I
T
E
E
N
I
I
N
N
V
G
P
I
L
K
Y
Y
R
H
-------------------
S
I
NAL
N
V
Y
L
G
L
N
N
G
-
K
-----------
V
L
L
S
Q
K
S
M
P
E
L
----
R
D
D
L
D
I
K
T
K
D
--------
W
Y
Q
E
A
L
K
T
N
--
D
-
I
F
V
-------
T
P
A
Y
L
D
T
V
L
K
Q
Y
V
I
T
Y
S
K
A
I
Y
K
----
D
GKI-
I
-----
G
V
------
L
G
V
D
I
P
S
E
D
L
Q
N
L
V
A
K
------
T
P
G
N
T
F
L
F
D
Q
K
N
K
--------
I
F
A
A
-
T
N
K
E
L
-
L
N
P
-
S
-
I
--------
D
--
H
S
P
V
L
-
N
A
-
Y
K
L
N
G
D
N
N
F
F
S
--
Y
--
K
--
L
N
N
-
E
E
R
L
G
A
C
T
-
K
V
F
A
Y
T
A
C
I
T
E
S
A
D
I
I
N
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
54.38
38%
-87
- C2 -
1QU7
-
MCP1_ECOLI
A:
[296-440]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Q
Q
A
A
S
L
E
Q
T
A
--
A
S
M
E
Q
L
T
A
T
V
K
Q
N
A
------
E
N
A
R
Q
A
S
H
L
A
L
S
A
S
E
T
A
Q
R
G
G
K
V
V
D
------
N
V
V
--------
Q
T
M
R
D
I
S
T
S
S
Q
K
I
A
D
I
I
S
V
I
D
G
I
A
F
Q
T
N
I
L
A
L
N
-------
A
A
V
E
A
A
R
A
G
E
Q
G
R
G
F
A
V
V
A
G
E
V
R
N
L
--------
A
Q
R
S
A
Q
A
A
R
E
I
K
S
L
I
E
D
S
V
G
K
V
D
V
G
S
T
L
V
E
S
-
A
G
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
52.54
39%
-74
- C2 -
3G67
-
?
A:
[95-187]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
Q
I
V
E
R
V
K
E
A
S
S
Q
I
G
E
T
L
E
N
I
R
S
I
E
K
L
I
Q
N
I
M
R
I
A
R
E
T
N
I
L
A
L
N
-------
A
T
I
E
A
A
R
A
G
E
A
G
K
G
F
M
I
V
A
N
E
V
Q
N
L
--------
S
N
E
T
N
E
V
T
K
Q
I
V
E
K
A
R
E
I
L
E
S
S
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
52.48
35%
-80
- C2 -
1QU7
-
MCP1_ECOLI
A:
[347-518]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
V
Q
T
M
R
D
I
S
T
S
S
Q
K
I
A
D
I
I
S
V
I
D
G
I
A
F
Q
T
N
I
L
A
L
N
-------
A
A
V
E
A
A
R
A
G
E
Q
G
R
G
F
A
V
V
A
G
E
V
R
N
L
--------
A
Q
R
S
A
Q
A
A
R
E
I
K
S
L
I
E
D
S
V
G
K
V
D
V
G
S
T
---------------
L
--------------
V
E
S
A
G
E
-
T
M
A
E
I
V
S
A
V
T
R
V
T
D
I
M
G
-------
E
I
A
S
A
S
D
E
Q
S
R
G
I
D
Q
V
G
L
A
V
A
E
M
D
-
R
V
T
Q
Q
N
A
A
L
V
E
Q
S
A
A
A
A
A
A
L
E
E
Q
----
A
S
R
L
T
E
A
V
A
V
F
R
I
Q
---------------------------------------------------------------------
54
Fugue
49.90
17%
50
- C1 -
4ZUZ
-
?
A:
[8-864]
---
D
V
I
K
F
K
E
P
E
R
C
D
Y
L
Y
V
D
E
N
N
K
V
H
I
L
L
P
I
V
GGDE
I
G
L
D
N
TC
Q
T
A
V
E
L
I
T
F
F
Y
G
S
A
H
S
G
V
T
K
Y
S
A
E
H
-
Q
L
S
E
Y
-
K
R
Q
L
E
E
D
I
K
A
I
N
S
Q
K
K
I
S
P
H
A
Y
D
D
L
L
K
E
-
K
I
E
R
-
L
Q
Q
I
E
K
Y
I
E
L
I
Q
V
L
K
K
Q
Y
D
EQN
D
I
R
Q
L
R
TGGIPQLP
S
G
V
K
---
E
I
I
K
S
S
E
N
A
-
F
A
V
R
L
S
P
YDNDK
F
T
R
F
--
D
D
P
L
F
----
N
V
K
R
N
I
S
K
Y
D
TPSRQ
A
P
I
P
I
Y
E
G
L
G
Y
R
-
L
R
-
S
T
L
FPEDK
T
P
T
P
I
N
K
K
S
L
R
D
K
V
K
S
T
V
L
S
H
Y
K
D
----
E
----
D
-----
R
I
DGEK
K
D
E
K
L
N
E
L
I
T
N
L
Q
N
E
L
V
K
E
L
V
K
S
D
P
Q
Y
S
K
L
S
L
S
K
D
P
R
G
K
E
I
N
YDY
L
V
N
S
-
L
M
L
V
D
-
N
D
S
-
E
-
I
--------
G
--
D
W
I
D
T
-
I
L
-
D
A
T
------
V
D
--
S
--
T
--
V
W
A
V
Q
A
S
S
P
F
Y
Q
G
A
K
---
E
I
S
S
D
R
D
A
D
K
I
S
I
R
V
Q
Y
L
L
A
E
A
N
I
Y
C
K
T
N
KLSDAN
F
G
E
F
F
D
K
E
P
H
A
T
E
I
A
K
R
V
K
E
G
F
T
Q
G
A
D
I
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P
I
I
Y
D
Y
I
N
S
NH
A
E
L
G
L
K
S
P
L
T
G
-
K
Q
Q
-
Q
E
I
T
D
K
F
T
K
H
Y
N
T
I
K
E
S
P
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FD
E
F
F
V
A
D
P
D
K
K
G
N
I
F
S
H
Q
G
R
I
S
C
H
F
L
D
F
F
T
R
Q
T
K
GKHPLG
D
L
A
S
H
Q
E
A
L
Q
E
G
T
S
N
R
L
H
H
K
N
E
V
V
A
Q
G
Y
--
E
K
L
D
Q
F
K
K
E
V
V
K
L
L
A
E
NK
P
K
E
L
L
D
Y
L
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T
S
P
T
G
V
P
N
Y
S
M
L
S
K
E
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A
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L
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L
L
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R
D
N
L
Q
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D
N
L
S
A
I
T
W
S
KYSSKPL
L
D
V
E
L
N
K
I
A
E
G
L
E
L
T
A
K
I
Y
N
E
K
R
G
R
EWWFAGSR
N
E
A
R
K
T
Q
C
E
E
L
Q
R
V
S
K
E
I
N
T
L
L
Q
S
E
S
L
T
K
S
Q
-
V
L
E
K
V
L
N
S
I
E
T
L
D
K
I
D
R
-------
D
I
S
A
E
S
N
W
F
Q
S
T
L
Q
K
E
V
R
L
F
R
D
Q
L
K
D
I
C
Q
L
D
K
Y
Y
F
K
S
T
K
L
D
E
I
I
S
L
E
M
E
E
Q
F
Q
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I
Q
D
P
A
V
Q
Q
I
V
R
D
L
P
S
H
C
H
N
D
E
A
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F
F
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T
L
N
P
E
E
A
A
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V
A
S
Y
L
S
L
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Y
R
E
I
N
KSTDK
K
T
L
L
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D
I
P
R
L
F
K
E
V
N
T
Q
L
L
S
K
L
K
E
E
KAID
E
Q
V
H
E
K
L
S
Q
L
ADKIAPEHFT
R
N
N
I
I
K
W
S
T
8
PsiBlast_PDB
46.65
37%
-73
- C2 -
3G6B
-
?
A:
[68-175]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
Q
L
V
S
V
I
------
Q
D
M
E
K
I
S
E
N
I
M
E
E
L
K
---
K
S
G
T
N
V
D
Q
I
V
E
R
V
K
E
A
S
S
Q
I
G
E
T
L
E
N
I
R
S
I
E
---
K
L
I
Q
N
I
M
R
----
I
A
R
E
T
N
I
L
A
L
N
-------
A
T
I
E
A
A
R
A
G
E
A
G
K
G
F
M
I
V
A
N
E
V
Q
N
L
--------
S
N
E
T
N
E
V
T
K
Q
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
46.28
17%
61
- C3 -
4XMR
2
?
A:
[74-249]
----------------------------------------------------------------------------------------------------------------------------
H
S
I
N
-------------------
A
L
---
N
V
Y
L
G
L
N
N
G
-
K
-----------
V
L
L
S
--
Q
K
S
--M
P
E
L
R
D
D
L
D
I
K
T
K
D
--------
W
Y
Q
E
A
L
K
T
--
N
D
-
I
F
V
-------
T
P
A
Y
L
D
T
V
L
K
Q
Y
V
I
T
Y
S
K
A
I
Y
K
DGK-
I
----
I
-----
G
V
------
L
G
V
D
I
P
S
E
D
L
Q
N
L
V
A
K
--
T
----
P
G
N
T
F
L
F
D
Q
K
N
K
--------
I
F
A
A
-
T
N
K
E
L
-
L
N
P
-
S
-
I
--------
D
H
S
P
V
L
N
A
Y
K
L
-
N
G
D
N
N
F
---
F
S
--
Y
--
K
--
L
N
N
E
E
R
L
G
A
C
T
K
V
F
--
A
Y
T
A
C
I
T
E
S
A
D
I
I
N
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
45.89
15%
14
- C3 -
3LIB
1
?
A:
[122-280]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
S
S
D
--------
Y
Y
Q
L
P
K
A
T
--
E
K
-
D
V
L
-------
T
E
P
Y
F
Y
E
--
G
V
F
M
V
S
Y
V
S
P
I
M
K
EGE-
F
----
A
-----
G
I
------
G
G
V
D
V
S
L
E
Y
V
D
E
V
V
S
K
--
V
R
T
F
D
T
G
Y
A
F
M
V
S
N
S
G
V
--------
I
L
S
H
-
P
T
H
K
D
W
I
G
K
-
K
D
L
YDFGG
E
E
L
E
--
K
A
S
R
D
-
I
K
-
N
G
I
G
G
H
---
L
E
--
T
A
D
P
--
T
T
G
K
T
V
I
L
F
Y
E
P
V
E
T
G
D
F
A
F
V
L
V
V
P
K
E
E
M
L
A
G
V
A
D
L
R
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------