@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu31260: (2016-07-22 )
MKTFINWLKKPSISKKLIVSFIAILIIPILILEFSSYRSASGKLDQEIMGNAKNSVDTFNTTVTNDLGEKAKAVTFFSESLKRSAFKGKSNQEEIKAKFSQYVSINQGVARIYGGADNGTYVQAPKEKLPEGYDPRQRPWYQDAMKAGGEIVVTDPYVAASDGSMVITIAQELKDGSGVVAMDITIDKLLEQMKQIKVGKEGYAFIATKNKTYVAHKNHKAGEKLSGDWVAKMYANDSGELQYTLNNEDKKMTYTTNELTGWKIAGTMYMDEIKDASKSVLTTGMIVLIASIVAGGILILFIVRSITKPLKRLVQSSKTISRGDLTETIEIHSKDELGELGESFNEMGQSLRSLISAIQDSVNNVAASSEQLTASAGQTSKATEHITMAIEQFSNGNEEQSEKVESSSHQLNLMNEGLQQVSQTSSDITKASIQSTEIAGTGEKFVQQTVGQMNSINQSVQQAEAVVKGLEGKSKDITSILRVINGIADQTNLLALNAAIEAARAGESGRGFSVVAEEVRKLAVQSADSAKEIEKLIQEIVAEIDTSLHMFKEVNQEVQSGLVVTDNTKESFQSIFSMTNEIAGKLQTMNSTVEQLSDRSQHVSAAVSGIADVSKESSASIQDIAASAEEQLASMEEISSSATTLAQMAEELRDLTKQFKIE
Atome Classification :
(20 SA)
.........10........20........30........40......-..50........60........70........80........----90........100.......110--........120..--.----------------------.----.-----------..----130.......140......-.150.......160.......170....----.-----..180.......190.......200....-...210.......220.-..--.--.-------.-------..230-..-.....240--.--......250.......260.......270.......280.......290.......300.......310.......320.......330...-.....340.......350.......360.......370.......380.......390.......400.......410.......420.......430-------.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540......-------.550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
K
T
F
I
N
W
L
KKPSI
S
K
K
L
I
V
S
F
I
A
I
L
I
I
P
I
L
I
L
EFSSYRSASGKL
D
Q
E
-
I
MGNAKNSVDTFNTTV
T
N
DLG
E
K
A
K
A
V
T
F
F
S
E
S
L
K
R
S
AFKGK----S
N
Q
E
E
I
K
A
K
F
S
Q
Y
V
S
INQ
G
V
A
R
---
I
YGGADNG
T
Y
V
QA--
P
----------------------
K
----
E
-----------KL----PEGYDPRQR
P
W
Y
Q
D
A
M
KAG-
G
E
I
V
V
TDP
Y
V
AASDG
S
M
V
I
T
I
A
Q
ELKDG----S-----
G
V
V
A
M
D
I
T
I
D
K
L
L
E
Q
M
K
QIKVGKE
G
Y
A
F
I
-
A
TKN
K
T
Y
V
AHKNHKA-G-EK--L--
S
-------
G
-------
D
W
V
A
K
-
M
Y-ANDSG
E
L
Q
--
Y
--
T
LNNED
K
K
M
T
Y
TTNELT
G
W
K
I
A
G
T
M
Y
M
D
E
I
K
D
A
S
K
S
V
L
T
T
G
M
I
V
L
I
A
S
I
VA
G
G
I
L
I
L
F
I
V
R
S
I
T
K
P
L
K
R
L
V
Q
SSKTISRGD
L
T
E
T
I
E
I-HS
K
-
D
E
L
G
E
L
G
E
S
F
N
E
M
G
Q
S
L
R
S
L
I
S
A
I
Q
D
S
V
N
N
VAASSE
Q
L
TASAGQTSKA
T
E
H
I
T
M
A
I
E
QFSNGN
E
E
Q
S
E
K
V
ESSSH
Q
L
N
L
M
N
E
G
L
Q
Q
V
S
Q
T
SSDITKAS-------IQSTEIAG
T
G
E
K
F
V
Q
Q
T
V
G
Q
M
N
S
I
N
Q
S
V
Q
Q
A
E
A
V
V
KGLEGK
S
K
D
I
T
S
I
L
R
V
I
N
GIADQT
N
L
L
A
L
N
A
A
I
E
A
ARAGESGR
G
F
S
V
V
A
E
E
V
R
K
L
A
VQSAD
S
A
K
E
I
E
K
L
I
Q
E
I
V
A
E
I
D
T
S
L
-------
H
M
F
K
E
V
N
Q
E
V
QS
G
L
V
V
TDN
T
K
E
S
F
Q
S
I
F
S
M
T
N
E
I
A
G
K
L
Q
T
M
N
S
T
V
E
Q
L
S
D
R
S
Q
H
V
S
A
A
V
S
G
I
A
DVSKESSA
S
I
Q
D
I
A
A
S
A
E
E
Q
L
A
S
M
E
E
I
S
S
S
A
T
T
L
A
Q
M
A
E
E
L
R
D
L
T
K
QFKIE
43
Fugue
72.92
27%
-68
- C1 -
2CH7
2
MCP2_THEMA
A:
[1-309]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
H
M
K
D
V
Q
T
E
T
F
S
V
A
E
S
I
E
E
I
S
K
A
N
E
E
I
T
N
Q
L
L
G
I
S
K
E
M
D
N
I
S
T
R
I
E
S
I
S
A
S
V
Q
E
T
T
A
G
S
E
E
I
S
S
A
T
K
N
I
A
D
S
A
Q
Q
A
A
S
F
A
-------
D
Q
S
T
Q
L
A
K
E
A
G
D
A
L
K
K
V
I
E
V
T
R
M
I
S
N
S
A
K
D
V
E
R
V
V
E
S
F
Q
K
G
A
E
E
I
T
S
F
V
E
T
I
N
A
I
A
E
Q
T
N
L
L
A
L
N
A
A
I
E
A
A
R
A
G
E
A
G
R
G
F
A
V
V
A
D
E
I
R
K
L
A
E
E
S
Q
Q
A
S
E
N
V
R
R
V
V
N
E
I
R
S
I
A
E
D
A
G
-------
K
V
S
S
E
I
T
A
R
V
E
E
G
T
K
L
A
D
E
A
D
E
K
L
N
S
I
V
G
A
V
E
R
I
N
E
M
L
Q
N
I
A
A
A
I
E
E
Q
T
A
A
V
D
E
I
T
T
A
M
T
E
N
A
K
N
A
E
E
I
T
N
S
V
K
E
V
N
A
R
L
Q
E
I
S
A
S
T
E
E
V
T
S
R
V
Q
T
I
R
E
N
V
Q
M
L
K
E
I
V
A
R
Y
K
--
1
PsiBlast_PDB
71.83
30%
-50
- C1 -
2CH7
2
MCP2_THEMA
A:
[22-309]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
A
N
E
E
I
T
N
Q
L
L
G
I
S
K
E
M
D
N
I
S
T
R
I
E
S
I
S
A
S
V
Q
E
T
T
A
G
S
E
E
I
S
S
A
T
K
N
I
A
D
S
A
Q
Q
A
A
S
F
A
D
Q
S
T
Q
L
A
K
E
A
G
D
A
L
K
K
V
I
E
V
T
R
M
I
S
N
S
A
K
D
V
E
R
V
V
E
S
F
Q
K
G
A
E
E
I
T
S
F
V
E
T
I
N
A
I
A
E
Q
T
N
L
L
A
L
N
A
A
I
E
A
A
R
A
G
E
A
G
R
G
F
A
V
V
A
D
E
I
R
K
L
A
E
E
S
Q
Q
A
S
E
N
V
R
R
V
V
N
E
I
R
S
I
A
E
D
A
G
-------
K
V
S
S
E
I
T
A
R
V
E
E
G
T
K
L
A
D
E
A
D
E
K
L
N
S
I
V
G
A
V
E
R
I
N
E
M
L
Q
N
I
A
A
A
I
E
E
Q
T
A
A
V
D
E
I
T
T
A
M
T
E
N
A
K
N
A
E
E
I
T
N
S
V
K
E
V
N
A
R
L
Q
E
I
S
A
S
T
E
E
V
T
S
R
V
Q
T
I
R
E
N
V
Q
M
L
K
E
I
V
A
R
Y
K
--
2
PsiBlast_PDB
69.70
30%
-57
- C1 -
3JA6
-
MCP2_THEMA
G:
[242-529]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
A
N
E
E
I
T
N
Q
L
L
G
I
S
K
E
M
D
N
I
S
T
R
I
E
S
I
S
A
S
V
Q
E
T
T
A
G
S
E
E
I
S
S
A
T
K
N
I
A
D
S
A
QQAASFA
D
Q
S
T
Q
L
A
K
E
A
G
D
A
L
K
K
V
I
E
V
T
R
M
I
S
N
S
A
K
D
V
E
R
V
V
E
S
F
Q
K
G
A
E
E
I
T
S
F
V
E
T
I
N
A
I
A
E
Q
T
N
L
L
A
L
N
A
A
I
E
A
A
R
A
G
E
A
G
R
G
F
A
V
V
A
D
E
I
R
K
L
A
E
E
S
Q
Q
A
S
E
N
V
R
R
V
V
N
E
I
R
S
I
A
E
D
A
G
-------
K
V
S
S
E
I
T
A
R
V
E
E
G
T
K
L
A
D
E
A
D
E
K
L
N
S
I
V
G
A
V
E
R
I
N
E
M
L
Q
N
I
A
A
A
I
E
E
Q
T
A
A
V
D
E
I
T
T
A
M
T
E
N
A
K
N
A
E
E
I
T
N
S
V
K
E
V
N
A
R
L
Q
E
I
S
A
S
T
E
E
V
T
S
R
V
Q
T
I
R
E
N
V
Q
M
L
K
E
I
V
A
R
Y
K
--
25
HHSearch
68.25
32%
-45
- C1 -
2CH7
2
MCP2_THEMA
A:
[94-309]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
K
K
V
I
E
V
T
R
M
I
S
N
S
A
K
D
V
E
R
V
V
E
S
F
Q
K
G
A
E
E
I
T
S
F
V
E
T
I
N
A
I
A
E
Q
T
N
L
L
A
L
N
A
A
I
E
A
A
R
A
G
E
A
G
R
G
F
A
V
V
A
D
E
I
R
K
L
A
E
E
S
Q
Q
A
S
E
N
V
R
R
V
V
N
E
I
R
S
I
A
E
D
A
G
-------
K
V
S
S
E
I
T
A
R
V
E
E
G
T
K
L
A
D
E
A
D
E
K
L
N
S
I
V
G
A
V
E
R
I
N
E
M
L
Q
N
I
A
A
A
I
E
E
Q
T
A
A
V
D
E
I
T
T
A
M
T
E
N
A
K
N
A
E
E
I
T
N
S
V
K
E
V
N
A
R
L
Q
E
I
S
A
S
T
E
E
V
T
S
R
V
Q
T
I
R
E
N
V
Q
M
L
K
E
I
V
A
R
Y
K
--
45
Fugue
67.55
19%
78
- C2 -
3C8C
2
?
A:
[1-240]
-------------------------------------------
S
L
R
S
M
V
S
D
S
V
D
E
I
V
D
G
V
S
K
T
T
A
E
V
I
N
G
R
K
S
I
A
Q
Y
A
T
S
L
I
E
N
N
---------
P
E
P
D
N
V
R
T
I
I
S
Q
P
L
I
K
N
T
F
L
L
V
---
G
F
G
L
E
K
D
G
S
N
I
N
N
D-
P
----------------------
S
----
W
-----------
N
P
----
G
P
T
W
D
P
R
V
R
P
W
Y
K
D
A
K
N
A
G
-
K
L
V
I
-
T
A
P
Y
A
D
S
A
S
G
E
I
L
V
S
V
A
T
P
V
K
D
S
----
A
TGQFL
G
S
I
F
Y
D
V
S
L
A
E
L
A
E
L
V
N
E
V
K
L
F
D
A
G
Y
V
F
I
-
V
S
E
D
G
T
T
I
A
H
P
K
K
E
F
-
N
-
G
K
--
P
M-
S
-------
E
-------
F
L
--
G
-
E
S
-
K
I
N
V
D
T
H
Q
--
V
--
I
I
N
G
K
P
Y
A
V
S
F
S
D
V
E
G
E
D
W
Y
V
G
V
V
I
D
E
E
I
A
Y
A
A
L
D
E
L
R
R
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
Fugue
63.01
16%
29
- C2 -
4XMR
2
?
A:
[1-249]
----------------------------------
G
I
D
P
F
T
K
T
S
L
Y
E
S
-
T
L
K
N
Q
T
D
L
L
K
V
T
Q
S
T
V
E
D
F
R
S
T
N
Q
S
F
T
R
A
L
E
K
D
I
A
N
L
P
Y
Q
S
L
----
I
T
E
E
N
I
I
N
N
V
G
P
I
L
K
Y
Y
R
H
S
I
N
AL
N
V
Y
L
G
L
N
N
G
K
V
L
L
S
Q
K
S
----------------------
M
----
P
-----------
E
L
----
R
D
D
L
D
I
K
T
K
D
W
Y
Q
E
A
L
K
-
T
-
N
D
I
F
V
T
P
A
Y
L
D
T
V
L
K
Q
Y
V
I
T
Y
S
K
A
I
Y
K
D
GKI-
I
-----
G
V
L
G
V
D
I
P
S
E
D
L
Q
N
L
V
A
K
T
P
----
G
N
T
F
L
F
D
Q
K
N
K
I
F
A
A
T
N
K
E
L
L
-
N
-
P
S
--
I
--
D
-------
H
-------
S
P
V
L
N
-
A
Y
-
K
L
N
G
D
N
N
F
--
F
--
S
Y
K
L
N
N
E
E
R
L
G
A
C
T
K
V
F
A
Y
T
A
C
I
T
E
S
A
D
I
I
N
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
61.99
18%
61
- C2 -
4XMR
2
?
A:
[8-249]
-----------------------------------------
T
S
L
Y
E
S
-
T
L
K
N
Q
T
D
L
L
K
V
T
Q
S
T
V
E
D
F
R
S
T
N
Q
S
F
T
R
A
L
E
K
D
I
A
N
L
P
Y
Q
S
L
IT
E
E
N
I
I
N
N
V
G
P
I
L
K
Y
Y
-
R
H
S
I
N
A
L
N
---
V
Y
L
G
L
N
N
G
K
V
L
L
S
--
Q
----------------------
K
----
S
-------------M
P
E
L
R
D
D
L
D
I
K
T
K
D
W
Y
Q
E
A
L
K
T
--
N
D
I
F
V
T
P
A
Y
L
D
T
V
L
K
Q
Y
V
I
T
Y
S
K
A
I
Y
K
D
GKI-
I
-----
G
V
L
G
V
D
I
P
S
E
D
L
Q
N
L
V
A
K
T
----
P
G
N
T
F
L
-
F
D
Q
K
N
K
I
F
A
A
T
N
K
E
L
-
L
-
N
P
--
S
--
I
-------
D
H
S
-----
P
V
L
N
A
Y
K
L
-
N
G
D
N
N
F
F
S
--
Y
--
K
L
N
N
E
E
R
L
G
A
C
T
K
V
F
--
A
Y
T
A
C
I
T
E
S
A
D
I
I
N
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
61.27
32%
79
- C1 -
3ZX6
2
B:
[3-216]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
T
R
P
I
I
E
L
S
N
T
V
D
K
I
A
E
G
N
L
E
A
E
V
P
H
-
Q
N
R
A
D
E
I
G
I
L
A
K
S
I
E
R
L
R
R
S
L
M
R
T
V
G
D
V
R
N
G
A
N
A
I
-------------
Y
S
G
A
S
E
-
I
A
T
G
N
N
D
L
S
S
R
T
E
Q
Q
A
A
S
L
E
E
T
A
A
S
M
E
Q
L
T
A
T
V
K
Q
N
A
E
N
A
R
Q
A
S
H
L
A
-------
L
S
A
S
E
T
A
Q
R
G
G
K
V
V
D
N
V
V
Q
T
M
R
D
I
S
T
S
S
Q
K
--------------
I
A
D
I
I
S
V
I
D
G
I
A
F
Q
T
N
I
L
A
L
N
A
A
V
E
A
A
R
A
G
E
Q
G
R
G
F
A
V
V
A
G
E
V
R
N
L
A
Q
R
S
A
Q
A
A
R
E
I
K
S
L
I
E
D
S
V
G
K
V
D
----------------------------------------------------------------------------------------------------------------------------
32
HHSearch
61.08
15%
-46
- C2 -
4JGP
1
KIND_BACSU
A:
[10-211]
-------------------------------------------
I
A
A
E
-
H
K
Q
E
A
S
V
L
L
N
L
H
R
N
K
I
N
Y
L
I
G
E
T
M
A
R
M
T
S
L
S
I
A
I
D
R
P
---------
V
D
I
K
K
M
Q
S
I
L
E
K
T
F
D
S
E
P
R
F
S
G
---
L
Y
F
L
N
A
K
G
D
V
T
A
S
--
T
----------------------
T
----
E
-----------
L
-----
K
T
K
V
N
L
A
D
R
S
F
F
I
K
A
K
E
T
--
K
K
T
V
I
S
D
S
Y
S
S
R
I
T
G
Q
P
I
F
T
I
C
V
P
V
L
D
S
KRNV
T
-----
D
Y
L
V
A
A
I
Q
I
D
Y
L
K
N
L
I
N
L
L
--
S
P
D
V
Y
I
E
V
-
V
N
Q
D
G
K
M
I
F
A
S
G
Q
A
S
-
H
-
A
---------------------------------
E
---------------
D
Q
K
P
V
S
G
Y
L
D
D
I
S
W
N
M
K
V
Y
P
N
P
V
T
I
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
Fugue
60.44
26%
-52
- C1 -
1QU7
-
MCP1_ECOLI
A:
[294-520]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
T
E
Q
Q
A
A
S
L
E
Q
T
A
A
S
M
E
Q
L
T
A
T
V
-------
K
Q
N
A
E
N
A
R
Q
A
S
H
L
A
L
S
A
S
E
T
A
Q
R
G
G
K
V
V
D
N
V
V
Q
T
M
R
D
I
S
T
S
S
Q
K
I
A
D
I
I
S
V
I
D
G
I
A
F
Q
T
N
I
L
A
L
N
A
A
V
E
A
A
R
A
G
E
Q
G
R
G
F
A
V
V
A
G
E
V
R
N
L
A
Q
R
S
A
Q
A
A
R
E
I
K
S
L
I
E
D
S
V
G
K
V
D
V
G
S
-------
T
L
V
E
S
A
G
E
T
M
A
E
I
V
S
A
V
T
R
V
T
D
I
M
G
E
I
A
S
A
S
D
E
Q
S
R
G
I
D
Q
V
G
L
A
V
A
E
M
D
R
V
T
Q
Q
N
A
A
L
V
E
Q
S
A
A
A
A
A
A
L
E
E
Q
A
S
R
L
T
E
A
V
A
V
F
R
I
Q
Q
Q
--------------------------
22
HHSearch
59.40
26%
138
- C1 -
3ZX6
1
MCP1_ECOLI
A:
[3-304]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
T
R
P
I
I
E
L
S
N
T
V
D
K
I
A
E
G
N
L
E
A
E
V
P
H
Q
N
R
A
-
D
E
I
G
I
L
A
K
S
I
E
R
L
R
R
S
L
M
R
T
V
G
D
V
R
N
G
A
N
A
I
Y
S
G
A
S
E
I
A
T
G
N
N
D
L
--------------
S
S
R
T
E
Q
Q
A
A
S
L
E
E
T
A
A
S
M
E
Q
L
T
A
T
V
K
Q
N
A
E
N
A
R
Q
A
S
H
L
A
-------
L
S
A
S
--------------
E
T
A
Q
R
G
G
K
V
V
D
N
V
V
Q
T
M
R
D
I
S
T
S
S
Q
K
I
A
D
I
I
S
V
I
D
G
I
A
F
Q
T
N
I
L
A
L
N
A
A
V
E
A
A
R
A
G
E
Q
G
R
G
F
A
V
V
A
G
E
V
R
N
L
A
Q
R
S
A
Q
A
A
R
E
I
K
S
L
I
E
D
S
V
G
K
V
D
V
G
S
-------
T
L
V
E
S
A
--------------
G
E
T
M
A
E
I
V
S
A
V
T
R
V
T
D
--------------
I
M
G
E
I
A
S
A
S
D
E
Q
S
R
G
I
D
Q
V
G
L
A
V
A
E
M
D
R
V
T
Q
Q
N
A
A
L
V
E
E
S
A
A
A
A
A
A
L
E
E
Q
A
S
R
L
T
E
A
V
A
V
F
R
I
-
3
PsiBlast_PDB
59.22
32%
100
- C1 -
3ZX6
1
MCP1_ECOLI
A:
[3-216]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
T
R
P
I
I
E
L
S
N
T
V
D
K
I
A
E
G
N
L
E
A
E
V
P
H
-
Q
N
R
A
D
E
I
G
I
L
A
K
S
I
E
R
L
R
R
S
L
M
R
T
V
G
D
V
R
N
G
A
N
A
I
-------------
Y
S
G
A
S
E
-
I
A
T
G
N
N
D
L
S
S
R
T
E
Q
Q
A
A
S
L
E
E
T
A
A
S
M
E
Q
L
T
A
T
V
K
Q
N
A
E
N
A
R
Q
A
S
H
L
A
-------
L
S
A
S
E
T
A
Q
R
G
G
K
V
V
D
N
V
V
Q
T
M
R
D
I
S
T
S
S
Q
K
--------------
I
A
D
I
I
S
V
I
D
G
I
A
F
Q
T
N
I
L
A
L
N
A
A
V
E
A
A
R
A
G
E
Q
G
R
G
F
A
V
V
A
G
E
V
R
N
L
A
Q
R
S
A
Q
A
A
R
E
I
K
S
L
I
E
D
S
V
G
K
V
D
----------------------------------------------------------------------------------------------------------------------------
23
HHSearch
57.11
35%
-71
- C1 -
1QU7
-
MCP1_ECOLI
A:
[349-518]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
T
M
R
D
I
S
T
S
S
Q
K
I
A
D
I
I
S
V
I
D
G
I
A
F
Q
T
N
I
L
A
L
N
A
A
V
E
A
A
R
A
G
E
Q
G
R
G
F
A
V
V
A
G
E
V
R
N
L
A
Q
R
S
A
Q
A
A
R
E
I
K
S
L
I
E
D
S
V
G
K
V
D
V
G
S
-------
T
L
V
E
--------------
S
A
G
E
T
M
A
E
I
V
S
--------------
A
V
T
R
V
T
D
I
M
G
E
I
A
S
A
S
D
E
Q
S
R
G
I
D
Q
V
G
L
A
V
A
E
M
D
R
V
T
Q
Q
N
A
A
L
V
E
Q
S
A
A
A
A
A
A
L
E
E
Q
A
S
R
L
T
E
A
V
A
V
F
R
I
Q
29
HHSearch
56.80
12%
-7
- C2 -
3LI9
1
?
A:
[12-273]
---------------------------------------------
K
L
-
A
Y
E
K
S
I
E
M
A
G
N
Y
A
N
Q
F
D
A
Q
M
E
A
N
Q
A
I
A
R
T
L
A
C
T
M
A
E
Y
G
S
Q
-------
D
R
E
E
A
M
S
I
I
K
R
I
L
N
E
N
P
Q
L
I
G
---
V
Y
L
G
Y
E
P
D
A
F
D
G
R
--
D
KNYINAP---------------
G
HDST
G
RF
V
P
Y
C
N
KING
P
V
I
I
--
E
P
L
V
H
Y
D
S
S
D
Y
Y
Q
L
P
K
T
T
--
G
K
D
T
L
T
E
P
Y
F
Y
E
--
G
I
F
M
V
S
Y
D
S
P
I
F
K
N
GEF-
A
-----
G
I
A
G
V
D
V
P
L
E
Y
V
D
D
V
A
S
S
I
R
T
F
D
T
G
Y
A
F
M
-
V
S
N
T
G
I
F
L
S
H
P
T
Q
K
N
-
W
I
G
E
KS
L
--
S
-------
D
FDV
E
E
I
K
N
A
A
S
D
-
I
R
-
E
G
I
G
G
H
V
E
--
I
K
D
P
I
T
G
K
T
V
I
M
F
Y
E
P
V
K
T
G
D
F
S
F
V
L
V
V
P
K
E
E
M
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
55.40
12%
4
- C2 -
3LIB
1
?
A:
[10-280]
--------------------------------------------
E
K
L
-
A
Y
Q
Q
S
V
E
M
A
S
N
Y
A
N
Q
F
D
A
D
M
K
A
N
L
A
I
A
R
T
I
S
T
T
M
E
S
Y
E
T
A
-------
D
R
D
E
A
L
L
I
L
E
N
L
L
R
D
N
P
H
L
L
G
---
T
Y
V
A
F
E
P
D
A
F
D
G
K
--
D
AEYTNSPAHDGTGRF
V
P
Y
W
NKM
N
----
G
-----------
T
A
S
V
--
A
P
L
L
H
Y
D
S
S
D
Y
Y
Q
L
P
K
A
T
--
E
K
D
V
L
T
E
P
Y
F
Y
E
--
G
V
F
M
V
S
Y
V
S
P
I
M
K
E
GEF-
A
-----
G
I
G
G
V
D
V
S
L
E
Y
V
D
E
V
V
S
K
V
R
T
F
D
T
G
Y
A
F
M
-
V
S
N
S
G
V
I
L
S
H
P
T
H
K
D
W
I
-
G
K
--
K
DL
Y
DFGG
E
E
L
E
-------
K
A
S
R
D
-
I
K
-
N
G
I
G
G
H
L
E
--
T
A
D
P
T
T
G
K
T
V
I
L
F
Y
E
P
V
E
T
G
D
F
A
F
V
L
V
V
P
K
E
E
M
L
A
G
V
A
D
L
R
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
55.14
38%
-68
- C1 -
3G67
-
?
A:
[101-192]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
K
E
A
S
S
Q
I
G
E
T
L
E
N
I
R
S
I
E
K
L
I
Q
N
I
M
R
I
A
R
E
T
N
I
L
A
L
N
A
T
I
E
A
A
R
A
G
E
A
G
K
G
F
M
I
V
A
N
E
V
Q
N
L
S
N
E
T
N
E
V
T
K
Q
I
V
E
K
A
R
E
I
L
E
S
S
Q
R
S
L
-------
E
N
----------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
54.69
30%
-65
- C1 -
3G67
-
?
A:
[117-245]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
S
I
E
K
L
I
Q
N
I
M
R
I
A
R
E
T
N
I
L
A
L
N
A
T
I
E
A
A
R
A
G
E
A
G
K
G
F
M
I
V
A
N
E
V
Q
N
L
S
N
E
T
N
E
V
T
K
Q
I
V
E
K
A
R
E
I
L
E
S
S
Q
R
S
L
E
N
L
E
F
M
A
N
L
F
E
T
V
G
K
T
L
Q
N
M
V
R
F
M
E
N
N
V
K
L
L
Q
E
V
R
N
----------
S
L
D
T
S
K
E
S
L
S
E
K
S
A
E
I
D
S
A
--------------------------------------------------------
7
PsiBlast_PDB
53.57
33%
-72
- C1 -
3G6B
-
?
A:
[117-245]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
S
I
E
K
L
I
Q
N
I
M
R
I
A
R
E
T
N
I
L
A
L
N
A
T
I
E
A
A
R
A
G
E
A
G
K
G
F
M
I
V
A
N
E
V
Q
N
L
S
N
E
T
N
E
V
T
K
Q
I
V
E
K
A
R
E
I
L
E
S
S
Q
R
S
L
E
N
L
E
F
M
A
N
L
F
E
T
V
G
K
T
L
Q
N
M
V
R
F
M
E
N
-------
I
V
K
L
L
Q
E
V
R
N
S
L
D
T
---
S
K
E
S
L
S
E
K
S
A
E
I
D
S
A
--------------------------------------------------------
4
PsiBlast_PDB
52.98
39%
-72
- C1 -
1QU7
-
MCP1_ECOLI
A:
[296-429]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Q
Q
A
A
S
L
E
Q
T
A
A
S
M
E
Q
L
T
A
T
V
K
Q
N
A
E
N
A
R
Q
A
S
H
L
A
-------
L
S
A
S
E
T
A
Q
R
G
G
K
V
V
D
N
V
V
Q
T
M
R
D
I
S
T
S
--------------
S
Q
K
I
A
D
I
I
S
V
I
D
G
I
A
F
Q
T
N
I
L
A
L
N
A
A
V
E
A
A
R
A
G
E
Q
G
R
G
F
A
V
V
A
G
E
V
R
N
L
A
Q
R
S
A
Q
A
A
R
E
I
K
S
L
I
E
D
S
V
G
K
V
D
----------------------------------------------------------------------------------------------------------------------------
27
HHSearch
52.76
10%
8
* C2 *
3LIF
2
?
A:
[9-246]
-------------------------------------------
A
L
A
Q
-
S
E
T
E
M
R
N
L
S
H
S
L
A
E
H
A
T
H
T
F
Q
G
A
D
V
V
L
D
D
I
V
S
F
M
K
W
R
P
H
--------
P
S
P
V
F
N
E
R
L
R
A
L
A
D
N
L
P
Q
L
S
D
---
V
A
I
L
D
A
D
G
Q
L
T
Y
A
--
S
----------------------
V
----
K
-----------
P
-----
V
P
A
L
D
N
S
D
R
S
Y
F
R
Y
H
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D
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L
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R
T
S
G
V
W
V
F
V
V
S
R
R
L
E
T
T
DGKF
F
-----
G
V
V
V
A
T
I
E
S
E
Y
F
S
T
F
Y
K
T
F
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L
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G
G
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L
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S
D
G
R
L
L
I
Q
W
P
S
L
Q
-
T
-
G
R
D-
M
--
A
N------
M
-------
V
L
F
Q
K
-
A
L
P
R
S
P
D
G
Y
Y
L
T
V
S
--
P
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L
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Y
L
A
Y
R
R
V
S
R
Y
P
L
V
V
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V
A
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D
S
V
L
S
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------