@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu31930: (2016-07-23 )
MIIGVPKEIKNNENRVALTPGGVSQLISNGHRVLVETGAGLGSGFENEAYESAGAEIIADPKQVWDAEMVMKVKEPLPEEYVYFRKGLVLFTYLHLAAEPELAQALKDKGVTAIAYETVSEGRTLPLLTPMSEVAGRMAAQIGAQFLEKPKGGKGILLAGVPGVSRGKVTIIGGGVVGTNAAKMAVGLGADVTIIDLNADRLRQLDDIFGHQIKTLISNPVNIADAVAEADLLICAVLIPGAKAPTLVTEEMVKQMKPGSVIVDVAIDQGGIVETVDHITTHDQPTYEKHGVVHYAVANMPGAVPRTSTIALTNVTVPYALQIANKGAVKALADNTALRAGLNTANGHVTYEAVARDLGYEYVPAEKALQDESSVAGA
Atome Classification :
(25 SA)
.........10........20........30........40........50........60..-..-.-...70.......-----.-80........90........100.......110.....---..120.-.-......130.......140.......150.......160.......170.......180.......190.......200.....-..210-------........220.....------..230------.........240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MIIGV
P
K
E
IKNNE
N
R
V
A
LTP
G
G
V
S
Q
L
I
SNG
H
R
V
L
V
ETGAGLGSGFEN
E
A
Y
E
SAGA
E
I
IA
D
P
K
Q
-VW-
D
-
A
E
M
V
M
K
V
KEPL
P
-----
E
-
E
Y
V
Y
F
R
K
G
L
V
L
F
T
Y
L
H
LAA
E
P
E
L
A
Q
A
L
K
DKG
V
T
A
I
A
Y
E
---TVS-EG-R-TL
P
L
LT
P
M
S
E
V
A
G
R
M
A
A
Q
I
G
A
Q
F
L
EKPKGG
K
G
I
L
L
AGVPGVSRG
K
V
T
I
I
GGGVVGTN
A
A
K
M
A
VGLGA
D
V
T
I
I
DL
N
A
D
R
L
R
Q
L
D
D
-
I
F
G
H
--------
Q
I
K
T
L
ISNPV
N
I
A
D
A
V
------AEA--------
D
L
L
I
C
A
V
LIPGAKAP
T
L
V
T
E
E
M
V
K
QMKPG
S
V
I
V
D
V
A
IDQGG
I
V
E
T
V
D
H
ITTHDQPT
Y
E
KH
G
V
V
H
Y
A
VANMPGAVPR
T
S
T
I
A
L
T
NVT
V
P
Y
A
L
Q
IANKGA
V
K
A
LAD
N
T
A
L
RAGLNTANG
H
V
T
Y
E
A
V
A
R
DLGYEYV
P
A
E
K
ALQDESSVAGA
112
HHSearch
78.67
58%
-68
- C3 -
1PJC
1
?
A:
[1-359]
M
E
I
G
V
P
K
E
I
K
N
Q
E
F
R
V
G
L
S
P
S
S
V
R
T
L
V
E
A
G
H
T
V
F
I
E
T
Q
A
G
I
G
A
G
F
A
D
Q
D
Y
V
Q
A
G
A
Q
V
V
P
S
A
K
D
-
A
W
-
S
-
R
E
M
V
V
K
V
K
E
P
L
P
-----
A
-
E
Y
D
L
M
Q
K
D
Q
L
L
F
T
Y
L
H
L
A
A
A
R
E
L
T
E
Q
L
M
R
V
G
L
T
A
I
A
Y
E
---
T
V
E
-
L
P
N
R
-
S
L
P
L
L
T
P
M
S
I
I
A
G
R
L
S
V
Q
F
G
A
R
F
L
E
R
Q
Q
G
G
R
G
V
L
L
G
G
V
P
G
V
K
P
G
K
V
V
I
L
G
G
G
V
V
G
T
E
A
A
K
M
A
V
G
L
G
A
Q
V
Q
I
F
D
I
N
V
E
R
L
S
Y
L
E
T
-
L
F
G
S
--------
R
V
E
L
L
Y
S
N
S
A
E
I
E
T
A
V
------
A
E
A
--------
D
L
L
I
G
A
V
L
V
P
G
R
R
A
P
I
L
V
P
A
S
L
V
E
Q
M
R
T
G
S
V
I
V
D
V
A
V
D
Q
G
G
C
V
E
T
L
-
H
P
T
S
H
T
Q
P
T
Y
E
V
F
G
V
V
H
Y
G
V
P
N
M
P
G
A
V
P
W
T
A
T
Q
A
L
N
N
S
T
L
P
Y
V
V
K
L
A
N
Q
G
L
K
-
A
L
E
T
D
D
A
L
A
K
G
L
N
V
Q
A
H
R
L
V
H
P
A
V
Q
Q
V
F
P
D
------------------
10
PsiBlast_PDB
78.27
57%
-66
- C3 -
1SAY
1
?
A:
[1-355]
M
E
I
G
V
P
K
E
I
K
N
Q
E
F
R
V
G
L
S
P
S
S
V
R
T
L
V
E
A
G
H
T
V
F
I
E
T
Q
A
G
I
G
A
G
F
A
D
Q
D
Y
V
Q
A
G
A
Q
V
V
P
S
A
K
D
-
A
W
-
S
-
R
E
M
V
V
K
V
K
E
P
L
P
-----
A
-
E
Y
D
L
M
Q
K
D
Q
L
L
F
T
Y
L
H
L
A
A
A
R
E
L
T
E
Q
L
M
R
V
G
L
T
A
I
A
Y
E
---
T
V
E
L
P
N
-
R
-
S
L
P
L
L
T
P
M
S
I
I
A
G
R
L
S
V
Q
F
G
A
R
F
L
E
R
Q
Q
G
G
R
G
V
L
L
G
G
V
P
G
V
K
P
G
K
V
V
I
L
G
G
G
V
V
G
T
E
A
A
K
M
A
V
G
L
G
A
Q
V
Q
I
F
D
I
N
V
E
R
L
S
Y
L
E
T
-
L
F
G
S
--------
R
V
E
L
L
Y
S
N
S
A
E
I
E
T
A
V
------
A
E
A
--------
D
L
L
I
G
A
V
L
V
P
G
R
R
A
P
I
L
V
P
A
S
L
V
E
Q
M
R
T
G
S
V
I
V
D
V
A
V
D
Q
G
G
C
V
E
T
L
-
H
P
T
S
H
T
Q
P
T
Y
E
V
F
G
V
V
H
Y
G
V
P
N
M
P
G
A
V
P
W
T
A
T
Q
A
L
N
N
S
T
L
P
Y
V
V
K
L
A
N
Q
G
-
L
K
A
L
E
T
D
D
A
L
A
K
G
L
N
V
Q
A
H
R
L
V
H
P
A
V
Q
Q
----------------------
9
PsiBlast_PDB
78.10
57%
-64
- C3 -
1PJB
-
?
A:
[1-355]
M
E
I
G
V
P
K
E
I
K
N
Q
E
F
R
V
G
L
S
P
S
S
V
R
T
L
V
E
A
G
H
T
V
F
I
E
T
Q
A
G
I
G
A
G
F
A
D
Q
D
Y
V
Q
A
G
A
Q
V
V
P
S
A
K
D
-
A
W
-
S
-
R
E
M
V
V
K
V
K
E
P
L
P
-----
A
-
E
Y
D
L
M
Q
K
D
Q
L
L
F
T
Y
L
H
L
A
A
A
R
E
L
T
E
Q
L
M
R
V
G
L
T
A
I
A
Y
E
---
T
V
E
L
P
N
-
R
-
S
L
P
L
L
T
P
M
S
I
I
A
G
R
L
S
V
Q
F
G
A
R
F
L
E
R
Q
Q
G
G
R
G
V
L
L
G
G
V
P
G
V
K
P
G
K
V
V
I
L
G
G
G
V
V
G
T
E
A
A
K
M
A
V
G
L
G
A
Q
V
Q
I
F
D
I
N
V
E
R
L
S
Y
L
E
T
-
L
F
G
S
--------
R
V
E
L
L
Y
S
N
S
A
E
I
E
T
A
V
------
A
E
A
--------
D
L
L
I
G
A
V
L
V
P
G
R
R
A
P
I
L
V
P
A
S
L
V
E
Q
M
R
T
G
S
V
I
V
D
V
A
V
D
Q
G
G
C
V
E
T
L
-
H
P
T
S
H
T
Q
P
T
Y
E
V
F
G
V
V
H
Y
G
V
P
N
M
P
G
A
V
P
W
T
A
T
Q
A
L
N
N
S
T
L
P
Y
V
V
K
L
A
N
Q
G
-
L
K
A
L
E
T
D
D
A
L
A
K
G
L
N
V
Q
A
H
R
L
V
H
P
A
V
Q
Q
----------------------
1
PsiBlast_PDB
77.82
62%
-58
- C3 -
2EEZ
-
?
A:
[1-368]
M
V
I
G
V
P
K
E
I
K
T
L
E
N
R
V
A
L
T
P
G
G
V
E
S
L
V
R
R
G
H
T
V
L
V
E
R
G
A
G
E
G
S
G
L
S
D
A
E
Y
A
R
A
G
A
E
L
V
G
R
-
E
E
-
A
W
-
G
-
A
E
M
V
V
K
V
K
E
P
L
P
-----
E
-
E
Y
G
F
L
R
E
G
L
I
L
F
T
Y
L
H
L
A
A
D
R
G
L
T
E
A
M
L
R
S
G
V
T
G
I
A
Y
E
---
T
V
Q
L
P
D
-
G
-
T
L
P
L
L
V
P
M
S
E
V
A
G
R
M
A
P
Q
V
G
A
Q
F
L
E
K
P
K
G
G
R
G
V
L
L
G
G
V
P
G
V
A
P
A
S
V
V
I
L
G
G
G
T
V
G
T
N
A
A
K
I
A
L
G
M
G
A
Q
V
T
I
L
D
V
N
H
K
R
L
Q
Y
L
D
D
-
V
F
G
G
--------
R
V
I
T
L
T
A
T
E
A
N
I
K
K
S
V
------
Q
H
A
--------
D
L
L
I
G
A
V
L
-------
K
L
V
T
R
D
M
L
S
L
M
K
E
G
A
V
I
V
D
V
A
--------------------
Y
V
V
D
G
V
V
H
Y
G
V
A
N
M
P
G
A
V
P
R
T
S
T
F
A
L
T
N
Q
T
L
P
Y
V
L
K
L
A
E
K
G
-
L
D
A
L
L
E
D
A
A
L
L
K
G
L
N
T
H
K
G
R
L
T
H
P
G
V
A
E
A
F
G
L
P
Y
T
P
P
E
E
A
L
R
--------
11
PsiBlast_PDB
77.38
57%
-67
- C3 -
1PJC
1
?
A:
[1-355]
M
E
I
G
V
P
K
E
I
K
N
Q
E
F
R
V
G
L
S
P
S
S
V
R
T
L
V
E
A
G
H
T
V
F
I
E
T
Q
A
G
I
G
A
G
F
A
D
Q
D
Y
V
Q
A
G
A
Q
V
V
P
S
A
K
D
-
A
W
-
S
-
R
E
M
V
V
K
V
K
E
P
L
P
-----
A
-
E
Y
D
L
M
Q
K
D
Q
L
L
F
T
Y
L
H
L
A
A
A
R
E
L
T
E
Q
L
M
R
V
G
L
T
A
I
A
Y
E
---
T
V
E
L
P
N
-
R
-
S
L
P
L
L
T
P
M
S
I
I
A
G
R
L
S
V
Q
F
G
A
R
F
L
E
R
Q
Q
G
G
R
G
V
L
L
G
G
V
P
G
V
K
P
G
K
V
V
I
L
G
G
G
V
V
G
T
E
A
A
K
M
A
V
G
L
G
A
Q
V
Q
I
F
D
I
N
V
E
R
L
S
Y
L
E
T
-
L
F
G
S
--------
R
V
E
L
L
Y
S
N
S
A
E
I
E
T
A
V
------
A
E
A
--------
D
L
L
I
G
A
V
L
V
P
G
R
R
A
P
I
L
V
P
A
S
L
V
E
Q
M
R
T
G
S
V
I
V
D
V
A
V
D
Q
G
G
C
V
E
T
L
-
H
P
T
S
H
T
Q
P
T
Y
E
V
F
G
V
V
H
Y
G
V
P
N
M
P
G
A
V
P
W
T
A
T
Q
A
L
N
N
S
T
L
P
Y
V
V
K
L
A
N
Q
G
-
L
K
A
L
E
T
D
D
A
L
A
K
G
L
N
V
Q
A
H
R
L
V
H
P
A
V
Q
Q
----------------------
111
HHSearch
74.91
51%
-38
- C3 -
4LMP
8
?
A:
[1-371]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
-
V
W
-
A
D
A
D
L
L
L
K
V
K
E
P
I
A
-----
A
-
E
Y
G
R
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
---
T
V
Q
-
T
A
D
G
-
A
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
-
E
F
C
G
--------
R
I
H
T
R
Y
S
S
A
Y
E
L
E
G
A
V
------
K
R
A
--------
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
D
Q
G
G
C
F
E
G
S
-
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
T
E
P
A
S
V
L
A
--------
116
HHSearch
74.73
63%
-37
- C3 -
2EEZ
-
?
A:
[1-367]
M
V
I
G
V
P
K
E
I
K
T
L
E
N
R
V
A
L
T
P
G
G
V
E
S
L
V
R
R
G
H
T
V
L
V
E
R
G
A
G
E
G
S
G
L
S
D
A
E
Y
A
R
A
G
A
E
L
V
G
R
-
E
E
-
A
W
-
G
-
A
E
M
V
V
K
V
K
E
P
L
P
-----
E
-
E
Y
G
F
L
R
E
G
L
I
L
F
T
Y
L
H
L
A
A
D
R
G
L
T
E
A
M
L
R
S
G
V
T
G
I
A
Y
E
---
T
V
Q
-
L
P
D
G
-
T
L
P
L
L
V
P
M
S
E
V
A
G
R
M
A
P
Q
V
G
A
Q
F
L
E
K
P
K
G
G
R
G
V
L
L
G
G
V
P
G
V
A
P
A
S
V
V
I
L
G
G
G
T
V
G
T
N
A
A
K
I
A
L
G
M
G
A
Q
V
T
I
L
D
V
N
H
K
R
L
Q
Y
L
D
D
V
F
G
G
R
--------
V
I
T
L
-
T
A
T
E
A
N
I
K
K
S
V
------
Q
H
A
--------
D
L
L
I
G
A
V
L
-------
K
L
V
T
R
D
M
L
S
L
M
K
E
G
A
V
I
V
D
V
A
--------------------
Y
V
V
D
G
V
V
H
Y
G
V
A
N
M
P
G
A
V
P
R
T
S
T
F
A
L
T
N
Q
T
L
P
Y
V
L
K
L
A
E
K
G
L
D
-
A
L
L
E
D
A
A
L
L
K
G
L
N
T
H
K
G
R
L
T
H
P
G
V
A
E
A
F
G
L
P
Y
T
P
P
E
E
A
L
---------
30
PsiBlast_CBE
74.68
51%
-42
- C3 -
2VHW
2
DHA_MYCTU
B:
[1-363]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
-
V
W
A
D
-
A
D
L
L
L
K
V
K
E
P
I
A
-----
A
-
E
Y
G
R
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
---
T
V
Q
-
T
A
-
D
G
A
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
-
E
F
C
G
--------
R
I
H
T
R
Y
S
S
A
Y
E
L
E
G
A
V
------
K
R
A
--------
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
D
Q
G
G
C
F
E
G
-
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
----------------
101
Fugue
74.61
57%
-33
- C3 -
1PJC
1
?
A:
[1-361]
M
E
I
G
V
P
K
E
I
K
N
Q
E
F
R
V
G
L
S
P
S
S
V
R
T
L
V
E
A
G
H
T
V
F
I
E
T
Q
A
G
I
G
A
G
F
A
D
Q
D
Y
V
Q
A
G
A
Q
V
V
P
S
A
K
D
-
A
W
S--
R
E
M
V
V
K
V
K
E
P
L
P
------A
E
Y
D
L
M
Q
K
D
Q
L
L
F
T
Y
L
H
L
A
A
A
R
E
L
T
E
Q
L
M
R
V
G
L
T
A
I
A
Y
E
---
T
V
E
-
L
P
-
N
R
S
L
P
L
L
T
P
M
S
I
I
A
G
R
L
S
V
Q
F
G
A
R
F
L
E
R
Q
Q
G
G
R
G
V
L
L
G
G
V
P
G
V
K
P
G
K
V
V
I
L
G
G
G
V
V
G
T
E
A
A
K
M
A
V
G
L
G
A
Q
V
Q
I
F
D
I
N
V
E
R
L
S
Y
L
E
T
-
L
F
G
S
R
V
E
L
L
Y
SN--------
S
A
E
I
E
T
A
V
------
A
E
A
--------
D
L
L
I
G
A
V
L
V
P
G
R
R
A
P
I
L
V
P
A
S
L
V
E
Q
M
R
T
G
S
V
I
V
D
V
A
V
D
Q
G
G
C
V
E
T
L
H
P
-
T
S
H
T
Q
P
T
Y
E
V
F
G
V
V
H
Y
G
V
P
N
M
P
G
A
V
P
W
T
A
T
Q
A
L
N
N
S
T
L
P
Y
V
V
K
L
A
N
Q
G
L
-
K
A
L
E
T
D
D
A
L
A
K
G
L
N
V
Q
A
H
R
L
V
H
P
A
V
Q
----------------
Q
V
F
P
D
L
A
4
PsiBlast_PDB
74.27
51%
-40
- C3 -
4LMP
8
?
A:
[1-363]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
-
V
W
A
D
-
A
D
L
L
L
K
V
K
E
P
I
A
-----
A
-
E
Y
G
R
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
---
T
V
Q
-
T
A
-
D
G
A
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
-
E
F
C
G
--------
R
I
H
T
R
Y
S
S
A
Y
E
L
E
G
A
V
------
K
R
A
--------
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
D
Q
G
G
C
F
E
G
-
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
----------------
28
PsiBlast_CBE
74.07
51%
-40
- C3 -
2VHW
1
DHA_MYCTU
D:
[1-363]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
-
V
W
A
D
-
A
D
L
L
L
K
V
K
E
P
I
A
-----
A
-
E
Y
G
R
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
---
T
V
Q
-
T
A
-
D
G
A
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
-
E
F
C
G
--------
R
I
H
T
R
Y
S
S
A
Y
E
L
E
G
A
V
------
K
R
A
--------
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
D
Q
G
G
C
F
E
G
-
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
----------------
29
PsiBlast_CBE
73.86
51%
-41
- C3 -
2VHW
1
DHA_MYCTU
C:
[1-363]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
-
V
W
A
D
-
A
D
L
L
L
K
V
K
E
P
I
A
-----
A
-
E
Y
G
R
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
---
T
V
Q
-
T
A
-
D
G
A
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
-
E
F
C
G
--------
R
I
H
T
R
Y
S
S
A
Y
E
L
E
G
A
V
------
K
R
A
--------
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
D
Q
G
G
C
F
E
G
-
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
----------------
5
PsiBlast_PDB
73.86
51%
-40
- C3 -
2VHW
2
DHA_MYCTU
A:
[1-363]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
-
V
W
A
D
-
A
D
L
L
L
K
V
K
E
P
I
A
-----
A
-
E
Y
G
R
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
---
T
V
Q
-
T
A
-
D
G
A
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
-
E
F
C
G
--------
R
I
H
T
R
Y
S
S
A
Y
E
L
E
G
A
V
------
K
R
A
--------
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
D
Q
G
G
C
F
E
G
-
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
----------------
22
PsiBlast_CBE
73.52
51%
-34
- C3 -
2VOJ
2
DHA_MYCTU
C:
[1-363]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
-
V
W
A
D
-
A
D
L
L
L
K
V
K
E
P
I
A
-----
A
-
E
Y
G
R
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
---
T
V
Q
-
T
A
-
D
G
A
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
-
E
F
C
G
--------
R
I
H
T
R
Y
S
S
A
Y
E
L
E
G
A
V
------
K
R
A
--------
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
D
Q
G
G
C
F
E
G
-
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
----------------
24
PsiBlast_CBE
73.44
51%
-33
- C3 -
2VHX
3
DHA_MYCTU
F:
[1-363]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
-
V
W
A
D
-
A
D
L
L
L
K
V
K
E
P
I
A
-----
A
-
E
Y
G
R
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
---
T
V
Q
-
T
A
-
D
G
A
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
-
E
F
C
G
--------
R
I
H
T
R
Y
S
S
A
Y
E
L
E
G
A
V
------
K
R
A
--------
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
D
Q
G
G
C
F
E
G
-
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
----------------
31
PsiBlast_CBE
73.16
51%
-32
- C3 -
2VHV
1
DHA_MYCTU
B:
[1-363]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
-
V
W
A
D
-
A
D
L
L
L
K
V
K
E
P
I
A
-----
A
-
E
Y
G
R
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
---
T
V
Q
-
T
A
-
D
G
A
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
-
E
F
C
G
--------
R
I
H
T
R
Y
S
S
A
Y
E
L
E
G
A
V
------
K
R
A
--------
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
N
Q
G
G
C
F
E
G
-
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
----------------
2
PsiBlast_PDB
73.05
51%
-33
- C3 -
2VOE
-
DHA_MYCTU
A:
[1-363]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
-
V
W
A
D
-
A
D
L
L
L
K
V
K
E
P
I
A
-----
A
-
E
Y
G
R
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
---
T
V
Q
-
T
A
-
D
G
A
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
-
E
F
C
G
--------
R
I
H
T
R
Y
S
S
A
Y
E
L
E
G
A
V
------
K
R
A
--------
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
D
Q
G
G
C
F
E
G
-
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
----------------
23
PsiBlast_CBE
73.02
51%
-35
- C3 -
2VHZ
1
DHA_MYCTU
B:
[1-363]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
-
V
W
A
D
-
A
D
L
L
L
K
V
K
E
P
I
A
-----
A
-
E
Y
G
R
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
---
T
V
Q
-
T
A
-
D
G
A
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
-
E
F
C
G
--------
R
I
H
T
R
Y
S
S
A
Y
E
L
E
G
A
V
------
K
R
A
--------
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
D
Q
G
G
C
F
E
G
-
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
----------------
26
PsiBlast_CBE
72.97
51%
-31
- C3 -
2VHW
1
DHA_MYCTU
F:
[1-363]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
-
V
W
A
D
-
A
D
L
L
L
K
V
K
E
P
I
A
-----
A
-
E
Y
G
R
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
---
T
V
Q
-
T
A
-
D
G
A
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
-
E
F
C
G
--------
R
I
H
T
R
Y
S
S
A
Y
E
L
E
G
A
V
------
K
R
A
--------
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
D
Q
G
G
C
F
E
G
-
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
----------------
8
PsiBlast_PDB
72.95
51%
-33
- C3 -
2VHV
1
DHA_MYCTU
A:
[1-363]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
-
V
W
A
D
-
A
D
L
L
L
K
V
K
E
P
I
A
-----
A
-
E
Y
G
R
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
---
T
V
Q
-
T
A
-
D
G
A
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
-
E
F
C
G
--------
R
I
H
T
R
Y
S
S
A
Y
E
L
E
G
A
V
------
K
R
A
--------
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
N
Q
G
G
C
F
E
G
-
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
----------------
3
PsiBlast_PDB
72.81
51%
-30
- C3 -
2VOJ
2
DHA_MYCTU
A:
[1-363]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
-
V
W
A
D
-
A
D
L
L
L
K
V
K
E
P
I
A
-----
A
-
E
Y
G
R
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
---
T
V
Q
-
T
A
-
D
G
A
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
-
E
F
C
G
--------
R
I
H
T
R
Y
S
S
A
Y
E
L
E
G
A
V
------
K
R
A
--------
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
D
Q
G
G
C
F
E
G
-
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
----------------
7
PsiBlast_PDB
72.45
51%
-36
- C3 -
2VHZ
1
DHA_MYCTU
A:
[1-363]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
-
V
W
A
D
-
A
D
L
L
L
K
V
K
E
P
I
A
-----
A
-
E
Y
G
R
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
---
T
V
Q
-
T
A
-
D
G
A
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
-
E
F
C
G
--------
R
I
H
T
R
Y
S
S
A
Y
E
L
E
G
A
V
------
K
R
A
--------
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
D
Q
G
G
C
F
E
G
-
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
----------------
21
PsiBlast_CBE
71.83
51%
-31
- C3 -
2VOJ
2
DHA_MYCTU
E:
[1-363]
M
R
V
G
I
P
T
E
T
K
N
N
E
F
R
V
A
I
T
P
A
G
V
A
E
L
T
R
R
G
H
E
V
L
I
Q
A
G
A
G
E
G
S
A
I
T
D
A
D
F
K
A
A
G
A
Q
L
V
G
T
A
D
Q
-
V
W
A
D
-
A
D
L
L
L
K
V
K
E
P
I
A
-----
A
-
E
Y
G
R
L
R
H
G
Q
I
L
F
T
F
L
H
L
A
A
S
R
A
C
T
D
A
L
L
D
S
G
T
T
S
I
A
Y
E
---
T
V
Q
-
T
A
-
D
G
A
L
P
L
L
A
P
M
S
E
V
A
G
R
L
A
A
Q
V
G
A
Y
H
L
M
R
T
Q
G
G
R
G
V
L
M
G
G
V
P
G
V
E
P
A
D
V
V
V
I
G
A
G
T
A
G
Y
N
A
A
R
I
A
N
G
M
G
A
T
V
T
V
L
D
I
N
I
D
K
L
R
Q
L
D
A
-
E
F
C
G
--------
R
I
H
T
R
Y
S
S
A
Y
E
L
E
G
A
V
------
K
R
A
--------
D
L
V
I
G
A
V
L
V
P
G
A
K
A
P
K
L
V
S
N
S
L
V
A
H
M
K
P
G
A
V
L
V
D
I
A
I
D
Q
G
G
C
F
E
G
-
S
R
P
T
T
Y
D
H
P
T
F
A
V
H
D
T
L
F
Y
C
V
A
N
M
P
A
S
V
P
K
T
S
T
Y
A
L
T
N
A
T
M
P
Y
V
L
E
L
A
D
H
G
W
R
A
A
C
R
S
N
P
A
L
A
K
G
L
S
T
H
E
G
A
L
L
S
E
R
V
A
T
D
L
G
V
P
F
----------------
58
PsiBlast_CBE
42.36
32%
-20
- C3 -
1NM5
3
PNTAA_RHORT
B:
[1-299]
M
K
I
A
I
P
K
E
R
R
P
G
E
D
R
V
A
I
S
P
E
V
V
K
K
L
V
G
L
G
F
E
V
I
V
E
Q
G
A
G
V
G
A
S
I
T
D
D
A
L
T
A
A
G
A
T
I
A
S
T
A
A
Q
A
L
S
-
Q
-
A
D
V
V
W
K
V
Q
R
P
M
T
AEEGT
D
-
E
V
A
L
I
K
E
G
A
V
L
M
C
H
L
G
A
L
T
N
R
P
V
V
E
A
L
T
K
R
K
I
T
A
Y
A
M
E
LMP
R
I
S
-
R
A
-
N
-
S
M
D
I
L
S
S
Q
S
N
L
A
G
Y
R
A
V
I
D
G
A
Y
E
F
A
R
---
A
F
P
M
M
M
T
A
A
G
T
V
P
P
A
R
V
L
V
F
G
V
G
V
A
G
L
Q
A
I
A
T
A
K
R
L
G
A
V
V
M
A
T
D
V
R
A
A
T
K
E
Q
V
E
S
-
L
G
G
K
--------
F
I
-
T
V
-----------EFRKK
Q
A
E
A
V
L
K
E
L
V
K
T
D
I
A
I
T
T
A
L
I
P
G
K
P
A
P
V
L
I
T
E
E
M
V
T
K
M
K
P
G
S
V
I
I
D
L
A
V
E
A
G
G
-----------------------------------------------------------------------------------------------------------
35
PsiBlast_CBE
40.96
32%
-12
- C3 -
1PTJ
3
PNTAA_RHORT
B:
[1-299]
M
K
I
A
I
P
K
E
R
R
P
G
E
D
R
V
A
I
S
P
E
V
V
K
K
L
V
G
L
G
F
E
V
I
V
E
Q
G
A
G
V
G
A
S
I
T
D
D
A
L
T
A
A
G
A
T
I
A
S
T
A
A
Q
A
L
S
-
Q
-
A
D
V
V
W
K
V
Q
R
P
M
T
AEEGT
D
-
E
V
A
L
I
K
E
G
A
V
L
M
C
H
L
G
A
L
T
N
R
P
V
V
E
A
L
T
K
R
K
I
T
A
Y
A
M
E
LMP
R
I
S
-
R
A
-
Q
-
S
M
D
I
L
S
S
Q
S
N
L
A
G
Y
R
A
V
I
D
G
A
Y
E
F
A
R
---
A
F
P
M
M
M
T
A
A
G
T
V
P
P
A
R
V
L
V
F
G
V
G
V
A
G
L
Q
A
I
A
T
A
K
R
L
G
A
V
V
M
A
T
D
V
R
A
A
T
K
E
Q
V
E
S
-
L
G
G
K
--------
F
I
-
T
V
D
D
E
A
M
------EFRKKQ
A
E
A
V
L
K
E
L
V
K
T
D
I
A
I
T
T
A
L
I
P
G
K
P
A
P
V
L
I
T
E
E
M
V
T
K
M
K
P
G
S
V
I
I
D
L
A
V
E
A
G
G
-----------------------------------------------------------------------------------------------------------