@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu32000: (2016-07-23 )
MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEGRHAEAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSKYMMDRRSGSIVTVGSNAAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITMHNLCVDGGATLGV
Atome Classification :
(25 SA)
.........10........20........30........40-----------.........50........-60..------......70........80........90........100.......110.......120.......130.........140.......150.......160.......170.......180.......190.......200......-.210......-----.220--.........230.......240.......250.......260
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MNAKGIE
G
K
I
A
F
I
T
G
A
A
Q
G
I
G
E
A
V
A
R
T
L
A
SQG
A
H
I
A
A
VDY------------
N
P
E
K
L
E
K
V
V
S
S
L
KAEGRHA-EAFP------ADVRDS
A
A
I
D
E
I
T
A
R
I
E
REMG
P
I
D
I
L
V
N
V
A
G
V
L
R
P
G
L
IHSLSDEE
W
E
A
T
F
S
VNSTGVFN
A
S
R
S
V
S
K
Y
--
M
M
DRRSG
S
I
V
T
VGSNAAGVPR
T
S
M
A
A
YASS
K
A
A
A
V
M
F
T
K
C
LG
L
E
L
A
E
Y
N
I
R
C
N
I
VSPGSTETD
M
Q
W
S
L
WADEN
G
A
E
Q
V
-
I
K
G
S
L
E
T
F
KT-----GI----
P
L
K
KLA
K
P
S
D
I
A
D
A
V
L
F
LVSGQAG
H
I
T
M
H
N
L
C
VDGGATLGV
2
PsiBlast_PDB
83.23
37%
-102
- C- -
3ENN
-
?
A:
[4-244]
-----
L
T
G
R
K
A
L
V
T
G
A
T
G
G
L
G
E
A
I
A
R
A
L
H
A
Q
G
A
I
V
G
L
H
G
T
------------
R
E
E
K
L
K
E
L
A
A
E
L
---
G
E
R
I
-
F
V
F
P
------
A
N
L
S
D
R
E
A
V
K
A
L
G
Q
K
A
E
E
E
M
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
G
L
F
V
R
M
S
D
E
D
W
D
A
V
L
T
V
N
L
T
S
V
F
N
L
T
R
E
L
T
H
P
--
M
M
R
R
R
N
G
R
I
I
N
I
T
S
I
V
G
V
T
G
N
P
G
Q
A
N
Y
C
A
S
K
A
G
L
I
G
F
S
K
S
L
A
Q
E
I
A
S
R
N
V
T
V
N
C
I
A
P
G
F
I
E
S
--------
K
Q
K
D
A
----
I
M
G
N
------------
I
----
P
M
K
R
M
G
V
G
A
D
I
A
A
A
V
V
Y
L
A
S
D
E
A
A
Y
V
T
G
Q
T
L
H
V
N
G
G
M
A
M
--
112
HHSearch
83.10
32%
-104
- C1 -
4J2H
7
?
A:
[7-256]
--
I
F
D
L
S
G
R
R
A
L
V
T
G
A
S
R
G
I
G
Q
S
I
A
V
A
L
A
E
A
G
A
H
V
A
V
T
A
R
------------
T
V
E
G
L
A
E
T
R
A
L
I
E
K
T
G
R
R
A
-
V
A
L
A
------
Q
D
V
R
D
V
E
A
C
A
S
V
T
R
A
A
A
E
G
L
G
G
L
D
I
L
V
N
N
A
G
F
E
N
V
R
P
S
F
D
V
D
E
A
L
W
D
T
I
V
S
T
N
L
K
G
A
F
F
C
A
Q
A
A
G
R
I
--
M
A
D
A
N
G
G
A
I
V
N
L
C
S
L
T
S
Y
V
G
I
P
T
A
V
P
Y
G
A
S
K
S
G
L
L
G
V
T
R
A
L
A
T
E
W
A
A
H
N
I
R
V
N
A
I
A
P
G
Y
F
R
T
A
M
T
A
G
F
Y
E
D
E
D
---------
W
Q
S
R
M
L
E
-----
K
I
----
P
Q
R
R
F
G
K
E
S
D
I
G
G
V
A
V
F
L
C
S
D
A
A
A
Y
I
T
G
H
C
I
P
A
D
G
G
Y
L
A
S
-
124
HHSearch
82.78
32%
-107
- C1 -
1FMC
2
HDHA_ECOLI
A:
[7-254]
---
L
R
L
D
G
K
C
A
I
I
T
G
A
G
A
G
I
G
K
E
I
A
I
T
F
A
T
A
G
A
S
V
V
V
S
D
I
------------
N
A
D
A
A
N
H
V
V
D
E
I
Q
Q
L
G
G
Q
A
-
F
A
C
R
------
C
D
I
T
S
E
Q
E
L
S
A
L
A
D
F
A
I
S
K
L
G
K
V
D
I
L
V
N
N
A
G
G
G
G
P
K
P
-
F
D
M
P
M
A
D
F
R
R
A
Y
E
L
N
V
F
S
F
F
H
L
S
Q
L
V
A
P
E
--
M
E
K
N
G
G
G
V
I
L
T
I
T
S
M
A
A
E
N
K
N
I
N
M
T
S
Y
A
S
S
K
A
A
A
S
H
L
V
R
N
M
A
F
D
L
G
E
K
N
I
R
V
N
G
I
A
P
G
A
I
L
T
D
A
L
K
S
V
I
T
P
----------
E
I
E
Q
K
M
L
Q
-----
H
T
----
P
I
R
R
L
G
Q
P
Q
D
I
A
N
A
A
L
F
L
C
S
P
A
A
S
W
V
S
G
Q
I
L
T
V
S
G
G
G
V
Q
E
L
88
PsiBlast_CBE
80.64
32%
-22
- C1 -
3S55
2
?
H:
[8-277]
-----
F
E
G
K
T
A
L
I
T
G
G
A
R
G
M
G
R
S
H
A
V
A
L
A
E
A
G
A
D
I
A
I
C
D
R
CENSDVVGYPLA
T
A
D
D
L
A
E
T
V
A
L
V
E
K
T
G
R
R
C
-
I
S
A
K
------
V
D
V
K
D
R
A
A
L
E
S
F
V
A
E
A
E
D
T
L
G
G
I
D
I
A
I
T
N
A
G
I
S
T
I
A
L
L
P
E
V
E
S
A
Q
W
D
E
V
I
G
T
N
L
T
G
T
F
N
T
I
A
A
V
A
P
G
--
M
I
K
R
N
Y
G
R
I
V
T
V
S
S
M
L
G
H
S
A
N
F
A
Q
A
S
Y
V
S
S
K
W
G
V
I
G
L
T
K
C
A
A
H
D
L
V
G
Y
G
I
T
V
N
A
V
A
P
G
N
I
E
T
P
M
T
H
N
D
F
V
F
G
T
M
R
P
-----
P
T
L
K
D
V
E
S
VFASL
H
L
----
Q
Y
A
P
F
L
K
P
E
E
V
T
R
A
V
L
F
L
V
D
E
A
S
S
H
I
T
G
T
V
L
P
I
D
A
G
A
T
---
15
PsiBlast_PDB
77.81
31%
-98
- C1 -
2C07
1
?
A:
[43-282]
------
E
N
K
V
A
L
V
T
G
A
G
R
G
I
G
R
E
I
A
K
M
L
A
K
S
V
S
H
V
I
C
I
S
R
------------
T
Q
K
S
C
D
S
V
V
D
E
I
K
S
F
G
Y
E
S
-
S
G
Y
A
------
G
D
V
S
K
K
E
E
I
S
E
V
I
N
K
I
L
T
E
H
K
N
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
F
L
R
M
K
N
D
E
W
E
D
V
L
R
T
N
L
N
S
L
F
Y
I
T
Q
P
I
S
K
R
--
M
I
N
N
R
Y
G
R
I
I
N
I
S
S
I
V
G
L
T
G
N
V
G
Q
A
N
Y
S
S
S
K
A
G
V
I
G
F
T
K
S
L
A
K
E
L
A
S
R
N
I
T
V
N
A
I
A
P
G
F
I
S
S
-----
I
------
S
E
Q
I
-
K
K
N
I
I
----
S
-----
N
I
----
P
A
G
R
M
G
T
P
E
E
V
A
N
L
A
C
F
L
S
S
D
K
S
G
Y
I
N
G
R
V
F
V
I
D
G
G
-----
21
PsiBlast_CBE
76.65
36%
-106
- C1 -
1Q7B
3
FABG_ECOLI
D:
[3-240]
-----
F
E
G
K
I
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
E
T
L
A
A
R
G
A
K
V
I
G
T
A
T
------------
S
E
N
G
A
Q
A
I
S
D
Y
L
G
A
N
G
K
----
G
L
M
------
L
N
V
T
D
P
A
S
I
E
S
V
L
E
K
I
R
A
E
F
G
E
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
D
E
E
W
N
D
I
I
E
T
N
L
S
S
V
F
R
L
S
K
A
V
M
R
A
--
M
M
K
K
R
H
G
R
I
I
T
I
G
S
V
V
G
T
M
G
N
G
G
Q
A
N
Y
A
A
A
K
A
G
L
I
G
F
S
K
S
L
A
R
E
V
A
S
R
G
I
T
V
N
V
V
A
P
G
F
I
E
T
D
M
T
R
A
L
S
D
D
Q
R
A
G
-----------
I
L
A
-----
Q
V
----
P
A
G
R
L
G
G
A
Q
E
I
A
N
A
V
A
F
L
A
S
D
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
-----
61
PsiBlast_CBE
76.63
33%
-65
- C1 -
3QRW
1
ACT3_STRCO
B:
[27-277]
--------
E
V
A
L
V
T
G
A
T
S
G
I
G
L
E
I
A
R
R
L
G
K
E
G
L
R
V
F
V
C
A
R
------------
G
E
E
G
L
R
T
T
L
K
E
L
R
E
A
G
V
E
A
-
D
G
R
T
------
C
D
V
R
S
V
P
E
I
E
A
L
V
A
A
V
V
E
R
Y
G
P
V
D
V
L
V
N
N
A
G
R
L
G
G
G
A
T
A
E
L
A
D
E
L
W
L
D
V
V
E
T
N
L
T
G
V
F
R
V
T
K
Q
V
L
K
A
GG
M
L
E
R
G
T
G
R
I
V
N
I
A
S
T
G
G
K
Q
G
V
V
H
A
A
P
Y
S
A
S
K
H
G
V
V
G
F
T
K
A
L
G
L
E
L
A
R
T
G
I
T
V
N
A
V
C
P
G
F
V
E
T
P
M
A
A
S
V
R
E
H
Y
S
D
I
W
E
V
S
T
E
E
A
F
D
R
I
T
A
-----
R
V
----
P
I
G
R
Y
V
Q
P
S
E
V
A
E
M
V
A
Y
L
I
G
P
G
A
A
A
V
T
A
Q
A
L
N
V
C
G
G
-----
92
PsiBlast_CBE
76.44
32%
-24
- C1 -
3S55
1
?
C:
[8-277]
-----
F
E
G
K
T
A
L
I
T
G
G
A
R
G
M
G
R
S
H
A
V
A
L
A
E
A
G
A
D
I
A
I
C
D
R
CENSDVVGYPLA
T
A
D
D
L
A
E
T
V
A
L
V
E
K
T
G
R
R
C
-
I
S
A
K
------
V
D
V
K
D
R
A
A
L
E
S
F
V
A
E
A
E
D
T
L
G
G
I
D
I
A
I
T
N
A
G
I
S
T
I
A
L
L
P
E
V
E
S
A
Q
W
D
E
V
I
G
T
N
L
T
G
T
F
N
T
I
A
A
V
A
P
G
--
M
I
K
R
N
Y
G
R
I
V
T
V
S
S
M
L
G
H
S
A
N
F
A
Q
A
S
Y
V
S
S
K
W
G
V
I
G
L
T
K
C
A
A
H
D
L
V
G
Y
G
I
T
V
N
A
V
A
P
G
N
I
E
T
P
M
T
H
N
D
F
V
F
G
--------
K
P
T
L
K
D
V
E
S
VFASL
H
L
----
Q
Y
A
P
F
L
K
P
E
E
V
T
R
A
V
L
F
L
V
D
E
A
S
S
H
I
T
G
T
V
L
P
I
D
A
G
A
T
---
90
PsiBlast_CBE
76.18
32%
-27
- C1 -
3S55
3
?
E:
[8-277]
-----
F
E
G
K
T
A
L
I
T
G
G
A
R
G
M
G
R
S
H
A
V
A
L
A
E
A
G
A
D
I
A
I
C
D
R
CENSDVVGYPLA
T
A
D
D
L
A
E
T
V
A
L
V
E
K
T
G
R
R
C
-
I
S
A
K
------
V
D
V
K
D
R
A
A
L
E
S
F
V
A
E
A
E
D
T
L
G
G
I
D
I
A
I
T
N
A
G
I
S
T
I
A
L
L
P
E
V
E
S
A
Q
W
D
E
V
I
G
T
N
L
T
G
T
F
N
T
I
A
A
V
A
P
G
--
M
I
K
R
N
Y
G
R
I
V
T
V
S
S
M
L
G
H
S
A
N
F
A
Q
A
S
Y
V
S
S
K
W
G
V
I
G
L
T
K
C
A
A
H
D
L
V
G
Y
G
I
T
V
N
A
V
A
P
G
N
I
E
T
P
M
T
H
N
D
F
V
F
G
T
-----------
K
D
V
E
S
VFASL
H
L
----
Q
Y
A
P
F
L
K
P
E
E
V
T
R
A
V
L
F
L
V
D
E
A
S
S
H
I
T
G
T
V
L
P
I
D
A
G
A
T
---
66
PsiBlast_CBE
75.37
33%
-73
- C1 -
2RHR
3
ACT3_STRCO
A:
[23-273]
--------
E
V
A
L
V
T
G
A
T
S
G
I
G
L
E
I
A
R
R
L
G
K
E
G
L
R
V
F
V
C
A
R
------------
G
E
E
G
L
R
T
T
L
K
E
L
R
E
A
G
V
E
A
-
D
G
R
T
------
C
D
V
R
S
V
P
E
I
E
A
L
V
A
A
V
V
E
R
Y
G
P
V
D
V
L
V
N
N
A
G
R
L
G
G
G
A
T
A
E
L
A
D
E
L
W
L
D
V
V
E
T
N
L
T
G
V
F
R
V
T
K
Q
V
L
K
A
GG
M
L
E
R
G
T
G
R
I
V
N
I
A
S
T
G
G
K
Q
G
V
V
H
A
A
P
Y
S
A
S
K
H
G
V
V
G
F
T
K
A
L
G
L
E
L
A
R
T
G
I
T
V
N
A
V
C
P
G
F
V
E
T
P
M
A
A
S
V
R
E
H
Y
S
D
I
W
E
V
S
T
E
E
A
F
D
R
I
T
A
-----
R
V
----
P
I
G
R
Y
V
Q
P
S
E
V
A
E
M
V
A
Y
L
I
G
P
G
A
A
A
V
T
A
Q
A
L
N
V
C
G
G
-----
91
PsiBlast_CBE
75.33
32%
-24
- C1 -
3S55
2
?
D:
[8-277]
-----
F
E
G
K
T
A
L
I
T
G
G
A
R
G
M
G
R
S
H
A
V
A
L
A
E
A
G
A
D
I
A
I
C
D
R
CENSDVVGYPLA
T
A
D
D
L
A
E
T
V
A
L
V
E
K
T
G
R
R
C
-
I
S
A
K
------
V
D
V
K
D
R
A
A
L
E
S
F
V
A
E
A
E
D
T
L
G
G
I
D
I
A
I
T
N
A
G
I
S
T
I
A
L
L
P
E
V
E
S
A
Q
W
D
E
V
I
G
T
N
L
T
G
T
F
N
T
I
A
A
V
A
P
G
--
M
I
K
R
N
Y
G
R
I
V
T
V
S
S
M
L
G
H
S
A
N
F
A
Q
A
S
Y
V
S
S
K
W
G
V
I
G
L
T
K
C
A
A
H
D
L
V
G
Y
G
I
T
V
N
A
V
A
P
G
N
I
E
T
P
M
T
H
N
D
F
V
F
G
T
M
R
P
D
L
-
E
K
P
T
L
K
D
V
E
S
VFAS
L
H
L
----
Q
Y
A
P
F
L
K
P
E
E
V
T
R
A
V
L
F
L
V
D
E
A
S
S
H
I
T
G
T
V
L
P
I
D
A
G
A
T
---
11
PsiBlast_PDB
75.26
34%
-97
- C1 -
3FTP
-
?
A:
[3-245]
---
K
T
L
D
K
Q
V
A
I
V
T
G
A
S
R
G
I
G
R
A
I
A
L
E
L
A
R
R
G
A
M
V
I
G
T
A
T
------------
T
E
A
G
A
E
G
I
G
A
A
F
K
Q
A
G
L
E
G
-
R
G
A
V
------
L
N
V
N
D
A
T
A
V
D
A
L
V
E
S
T
L
K
E
F
G
A
L
N
V
L
V
N
N
A
G
I
T
Q
D
Q
L
A
M
R
M
K
D
D
E
W
D
A
V
I
D
T
N
L
K
A
V
F
R
L
S
R
A
V
L
R
P
--
M
M
K
A
R
G
G
R
I
V
N
I
T
S
V
V
G
S
A
G
N
P
G
Q
V
N
Y
A
A
A
K
A
G
V
A
G
M
T
R
A
L
A
R
E
I
G
S
R
G
I
T
V
N
C
V
A
P
G
F
I
D
T
D
M
T
K
G
L
P
Q
E
Q
Q
T
A
-----------
L
K
T
-----
Q
I
----
P
L
G
R
L
G
S
P
E
D
I
A
H
A
V
A
F
L
A
S
P
Q
A
G
Y
I
T
G
T
T
L
H
V
N
G
G
-----
87
PsiBlast_CBE
74.79
32%
-103
- C1 -
3O03
3
?
A:
[32-280]
-----
L
K
G
K
I
A
L
V
T
G
A
S
Y
G
I
G
F
A
I
A
S
A
Y
A
K
A
G
A
T
I
V
F
N
D
I
------------
N
Q
E
L
V
D
R
G
M
A
A
Y
K
A
A
G
I
N
A
-
H
G
Y
V
------
C
D
V
T
D
E
D
G
I
Q
A
M
V
A
Q
I
E
S
E
V
G
I
I
D
I
L
V
N
N
A
G
I
I
R
R
V
P
M
I
E
M
T
A
A
Q
F
R
Q
V
I
D
I
D
L
N
A
P
F
I
V
S
K
A
V
I
P
S
--
M
I
K
K
G
H
G
K
I
I
N
I
C
S
M
M
S
E
L
G
R
E
T
V
S
A
Y
A
A
A
K
G
G
L
K
M
L
T
K
N
I
A
S
E
Y
G
E
A
N
I
Q
C
N
G
I
G
P
G
Y
I
A
T
P
Q
T
-------------------
H
P
F
D
Q
-----
F
I
I
A
K
T
P
A
A
R
W
G
E
A
E
D
L
M
G
P
A
V
F
L
A
S
D
A
S
N
F
V
N
G
H
I
L
Y
V
D
G
G
-----
22
PsiBlast_CBE
74.76
36%
-106
- C1 -
1Q7B
3
FABG_ECOLI
C:
[3-240]
-----
F
E
G
K
I
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
E
T
L
A
A
R
G
A
K
V
I
G
T
A
T
------------
S
E
N
G
A
Q
A
I
S
D
Y
L
G
A
N
G
K
----
G
L
M
------
L
N
V
T
D
P
A
S
I
E
S
V
L
E
K
I
R
A
E
F
G
E
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
D
E
E
W
N
D
I
I
E
T
N
L
S
S
V
F
R
L
S
K
A
V
M
R
A
--
M
M
K
K
R
H
G
R
I
I
T
I
G
S
V
V
G
T
M
G
N
G
G
Q
A
N
Y
A
A
A
K
A
G
L
I
G
F
S
K
S
L
A
R
E
V
A
S
R
G
I
T
V
N
V
V
A
P
G
F
I
E
T
D
M
T
R
A
L
S
D
D
Q
R
A
G
-----------
I
L
A
-----
Q
V
----
P
A
G
R
L
G
G
A
Q
E
I
A
N
A
V
A
F
L
A
S
D
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
-----
79
PsiBlast_CBE
74.64
33%
-69
- C1 -
2RH4
1
ACT3_STRCO
B:
[23-273]
--------
E
V
A
L
V
T
G
A
T
S
G
I
G
L
E
I
A
R
R
L
G
K
E
G
L
R
V
F
V
C
A
R
------------
G
E
E
G
L
R
T
T
L
K
E
L
R
E
A
G
V
E
A
-
D
G
R
T
------
C
D
V
R
S
V
P
E
I
E
A
L
V
A
A
V
V
E
R
Y
G
P
V
D
V
L
V
N
N
A
G
R
P
G
G
G
A
T
A
E
L
A
D
E
L
W
L
D
V
V
E
T
N
L
T
G
V
F
R
V
T
K
Q
V
L
K
A
GG
M
L
E
R
G
T
G
R
I
V
N
I
A
S
T
G
G
K
Q
G
V
V
H
A
A
P
Y
S
A
S
K
H
G
V
V
G
F
T
K
A
L
G
L
E
L
A
R
T
G
I
T
V
N
A
V
C
P
G
F
V
E
T
P
M
A
A
S
V
R
E
H
Y
S
D
I
W
E
V
S
T
E
E
A
F
D
R
I
T
A
-----
R
V
----
P
I
G
R
Y
V
Q
P
S
E
V
A
E
M
V
A
Y
L
I
G
P
G
A
A
A
V
T
A
Q
A
L
N
V
C
G
G
-----
68
PsiBlast_CBE
74.64
33%
-69
- C1 -
4DBZ
1
ACT3_STRCO
A:
[27-277]
--------
E
V
A
L
V
T
G
A
T
S
G
I
G
L
E
I
A
R
R
L
G
K
E
G
L
R
V
F
V
C
A
R
------------
G
E
E
G
L
R
T
T
L
K
E
L
R
E
A
G
V
E
A
-
D
G
R
T
------
C
D
V
R
S
V
P
E
I
E
A
L
V
A
A
V
V
E
R
Y
G
P
V
D
V
L
V
N
N
A
G
R
P
G
G
G
A
T
A
E
L
A
D
E
L
W
L
D
V
V
E
T
N
L
T
G
V
F
R
V
T
K
Q
V
L
K
A
G
G
M
L
E
R
G
T
G
R
I
V
N
I
A
S
T
G
G
K
Q
G
L
V
H
A
A
P
Y
S
A
S
K
H
G
V
V
G
F
T
K
A
L
G
L
E
L
A
R
T
G
I
T
V
N
A
V
C
P
G
F
V
E
T
P
M
A
A
S
V
R
E
H
Y
S
D
I
W
E
V
S
T
E
E
A
F
D
R
I
T
A
-----
R
V
----
P
I
G
R
Y
V
Q
P
S
E
V
A
E
M
V
A
Y
L
I
G
P
G
A
A
A
V
T
A
Q
A
L
N
V
C
G
G
-----
76
PsiBlast_CBE
74.57
33%
-71
- C1 -
1W4Z
5
ACT3_STRCO
A:
[27-277]
--------
E
V
A
L
V
T
G
A
T
S
G
I
G
L
E
I
A
R
R
L
G
K
E
G
L
R
V
F
V
C
A
R
------------
G
E
E
G
L
R
T
T
L
K
E
L
R
E
A
G
V
E
A
-
D
G
R
T
------
C
D
V
R
S
V
P
E
I
E
A
L
V
A
A
V
V
E
R
Y
G
P
V
D
V
L
V
N
N
A
G
R
P
G
G
G
A
T
A
E
L
A
D
E
L
W
L
D
V
V
E
T
N
L
T
G
V
F
R
V
T
K
Q
V
L
K
A
GG
M
L
E
R
G
T
G
R
I
V
N
I
A
S
T
G
G
K
Q
G
V
V
H
A
A
P
Y
S
A
S
K
H
G
V
V
G
F
T
K
A
L
G
L
E
L
A
R
T
G
I
T
V
N
A
V
C
P
G
F
V
E
T
P
M
A
A
S
V
R
E
H
Y
S
D
I
W
E
V
S
T
E
E
A
F
D
R
I
T
A
-----
R
V
----
P
I
G
R
Y
V
Q
P
S
E
V
A
E
M
V
A
Y
L
I
G
P
G
A
A
A
V
T
A
Q
A
L
N
V
C
G
G
-----
93
PsiBlast_CBE
74.47
32%
-27
- C1 -
3S55
3
?
B:
[8-277]
-----
F
E
G
K
T
A
L
I
T
G
G
A
R
G
M
G
R
S
H
A
V
A
L
A
E
A
G
A
D
I
A
I
C
D
R
CENSDVVGYPLA
T
A
D
D
L
A
E
T
V
A
L
V
E
K
T
G
R
R
C
-
I
S
A
K
------
V
D
V
K
D
R
A
A
L
E
S
F
V
A
E
A
E
D
T
L
G
G
I
D
I
A
I
T
N
A
G
I
S
T
I
A
L
L
P
E
V
E
S
A
Q
W
D
E
V
I
G
T
N
L
T
G
T
F
N
T
I
A
A
V
A
P
G
--
M
I
K
R
N
Y
G
R
I
V
T
V
S
S
M
L
G
H
S
A
N
F
A
Q
A
S
Y
V
S
S
K
W
G
V
I
G
L
T
K
C
A
A
H
D
L
V
G
Y
G
I
T
V
N
A
V
A
P
G
N
I
E
T
P
M
T
H
N
D
F
V
F
G
T
M
R
------
P
T
L
K
D
V
E
S
V
F
A
S
L
H
L
----
Q
Y
A
P
F
L
K
P
E
E
V
T
R
A
V
L
F
L
V
D
E
A
S
S
H
I
T
G
T
V
L
P
I
D
A
G
A
T
---
4
PsiBlast_PDB
74.33
36%
-100
- C1 -
1Q7B
4
FABG_ECOLI
A:
[3-240]
-----
F
E
G
K
I
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
E
T
L
A
A
R
G
A
K
V
I
G
T
A
T
------------
S
E
N
G
A
Q
A
I
S
D
Y
L
G
A
N
G
K
----
G
L
M
------
L
N
V
T
D
P
A
S
I
E
S
V
L
E
K
I
R
A
E
F
G
E
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
D
E
E
W
N
D
I
I
E
T
N
L
S
S
V
F
R
L
S
K
A
V
M
R
A
--
M
M
K
K
R
H
G
R
I
I
T
I
G
S
V
V
G
T
M
G
N
G
G
Q
A
N
Y
A
A
A
K
A
G
L
I
G
F
S
K
S
L
A
R
E
V
A
S
R
G
I
T
V
N
V
V
A
P
G
F
I
E
T
D
M
T
R
A
L
S
D
D
Q
R
A
G
-----------
I
L
A
-----
Q
V
----
P
A
G
R
L
G
G
A
Q
E
I
A
N
A
V
A
F
L
A
S
D
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
-----
75
PsiBlast_CBE
74.15
33%
-56
- C1 -
1W4Z
5
ACT3_STRCO
B:
[27-277]
--------
E
V
A
L
V
T
G
A
T
S
G
I
G
L
E
I
A
R
R
L
G
K
E
G
L
R
V
F
V
C
A
R
------------
G
E
E
G
L
R
T
T
L
K
E
L
R
E
A
G
V
E
A
-
D
G
R
T
------
C
D
V
R
S
V
P
E
I
E
A
L
V
A
A
V
V
E
R
Y
G
P
V
D
V
L
V
N
N
A
G
R
P
G
G
G
A
T
A
E
L
A
D
E
L
W
L
D
V
V
E
T
N
L
T
G
V
F
R
V
T
K
Q
V
L
K
A
G
G
M
L
E
R
G
T
G
R
I
V
N
I
A
S
T
G
G
K
Q
G
V
V
H
A
A
P
Y
S
A
S
K
H
G
V
V
G
F
T
K
A
L
G
L
E
L
A
R
T
G
I
T
V
N
A
V
C
P
G
F
V
E
T
P
M
A
A
S
V
R
E
H
Y
-------
T
E
E
A
F
D
R
I
T
A
-----
R
V
----
P
I
G
R
Y
V
Q
P
S
E
V
A
E
M
V
A
Y
L
I
G
P
G
A
A
A
V
T
A
Q
A
L
N
V
C
G
G
-----
14
PsiBlast_PDB
70.18
34%
-102
- C1 -
4I08
6
FABG_VIBCH
A:
[10-247]
-----
L
E
G
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
I
G
T
A
T
------------
S
E
S
G
A
Q
A
I
S
D
Y
L
---
G
D
N
G
-
K
G
M
A
------
L
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
--
M
M
K
K
R
Q
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M
-----
N
D
E
Q
R
T
A
T
L
-
A
Q
--------------
V
----
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
S
P
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
-----
35
PsiBlast_CBE
67.11
34%
-101
- C1 -
3RRO
13
FABG_VIBCH
B:
[10-247]
-----
L
E
G
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
I
G
T
A
T
------------
S
E
S
G
A
Q
A
I
S
D
Y
L
---
G
D
N
G
-
K
G
M
A
------
L
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
--
M
M
K
K
R
Q
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M
T
K
A
L
-
N
D
E
Q
R
T
A
T
L
-
A
Q
--------------
V
----
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
S
P
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
-----
13
PsiBlast_PDB
66.78
34%
-98
- C1 -
3RRO
11
FABG_VIBCH
A:
[10-247]
-----
L
E
G
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
I
G
T
A
T
------------
S
E
S
G
A
Q
A
I
S
D
Y
L
---
G
D
N
G
-
K
G
M
A
------
L
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
--
M
M
K
K
R
Q
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M
T
K
A
L
-
N
D
E
Q
R
T
A
T
L
-
A
Q
--------------
V
----
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
S
P
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
-----
50
PsiBlast_CBE
61.49
32%
-19
- C1 -
4NBU
1
?
C:
[11-250]
-----
L
Q
D
K
V
A
I
I
T
G
A
A
N
G
I
G
L
E
A
A
R
V
F
M
K
E
G
A
K
V
V
I
A
D
F
------------
N
-----------
E
A
A
G
K
E
A
V
E
A
N
P
GVVFIR
V
D
V
S
D
R
E
S
V
H
R
L
V
E
N
V
A
E
R
F
G
K
I
D
I
L
I
N
N
A
G
I
T
R
D
S
M
L
S
K
M
T
V
D
Q
F
Q
Q
V
I
N
V
N
L
T
G
V
F
H
C
T
Q
A
V
L
P
Y
--
M
A
E
Q
G
K
G
K
I
I
N
T
S
S
V
T
G
T
Y
G
N
V
G
Q
T
N
Y
A
A
A
K
A
G
V
I
G
M
T
K
T
W
A
K
E
L
A
R
K
G
I
N
V
N
A
V
A
P
G
F
T
E
T
A
M
----------
V
A
E
V
-
P
E
K
V
I
E
K
M
K
A
-----
Q
V
----
P
M
G
R
L
G
K
P
E
D
I
A
N
A
Y
L
F
L
A
S
H
E
S
D
Y
V
N
G
H
V
L
H
V
D
G
G
I
M
M
--
52
PsiBlast_CBE
59.76
32%
-17
- C1 -
4NBU
1
?
A:
[11-250]
-----
L
Q
D
K
V
A
I
I
T
G
A
A
N
G
I
G
L
E
A
A
R
V
F
M
K
E
G
A
K
V
V
I
A
D
F
------------
N
-----------
E
A
A
G
K
E
A
V
E
A
N
P
G
V
V
F
I
R
V
D
V
S
D
R
E
S
V
H
R
L
V
E
N
V
A
E
R
F
G
K
I
D
I
L
I
N
N
A
G
I
T
R
D
S
M
L
S
K
M
T
V
D
Q
F
Q
Q
V
I
N
V
N
L
T
G
V
F
H
C
T
Q
A
V
L
P
Y
--
M
A
E
Q
G
K
G
K
I
I
N
T
S
S
V
T
G
T
Y
G
N
V
G
Q
T
N
Y
A
A
A
K
A
G
V
I
G
M
T
K
T
W
A
K
E
L
A
R
K
G
I
N
V
N
A
V
A
P
G
F
T
E
T
A
M
----------
V
A
E
V
-
P
E
K
V
I
E
K
M
K
A
-----
Q
V
----
P
M
G
R
L
G
K
P
E
D
I
A
N
A
Y
L
F
L
A
S
H
E
S
D
Y
V
N
G
H
V
L
H
V
D
G
G
I
M
M
--