@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu33950: (2016-07-27 )
MNQLIQAQKKLLPDLLLVMQKRFEILQYIRLTEPIGRRSLSASLGISERVLRGEVQFLKEQNLVDIKTNGMTLTEEGYELLSVLEDTMKDVLGLTLLEKTLKERLNLKDAIIVSGDSDQSPWVKKEMGRAAVACMKKRFSGKNIVAVTGGTTIEAVAEMMTPDSKNRELLFVPARGGLGEDVKNQANTICAHMAEKASGTYRLLFVPGQLSQGAYSSIIEEPSVKEVLNTIKSASMLVHGIGEAKTMAQRRNTPLEDLKKIDDNDAVTEAFGYYFNADGEVVHKVHSVGMQLDDIDAIPDIIAVAGGSSKAEAIEAYFKKPRNTVLVTDEGAAKKLLRDE
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......-140-.......150.......160...-.....170.......180.-...--.--....190.....-..200.......210..-..-....220........230.......240...-----.-..---.250----...---..-..-260.......270.-......---280.---.----...--..290.......300.......310.......320-.-.......330.......340
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
N
Q
L
I
Q
A
Q
K
K
L
L
P
D
L
L
L
V
M
Q
K
R
F
E
I
L
Q
Y
I
RLTEPIGRRSLSASLG
I
S
E
R
V
L
R
G
E
V
Q
F
L
KEQN
L
V
D
I
KTN
G
M
T
L
T
E
E
G
Y
E
L
L
S
V
L
E
D
T
M
K
D
V
L
G
L
T
L
L
E
K
T
L
K
E
RLNLK
D
A
I
I
V
SGDSDQS
P
W
V
K
K
E
M
G
R
A
A
V
A
C
M
K
K
RF-SGK-
N
I
V
A
V
TGG
T
T
I
E
A
V
A
E
M
M-TPDS-KN
R
E
L
L
F
VPARGGLG
E
--
D
-
V
K
N
--
Q
--
A
N
T
I
C
A
H
M
A
E
KA-SG
T
Y
R
L
L
FVPGQL-SQ
G
-
A
Y
-
S
S
I
IE-EP
S
V
K
E
V
L
N
T
I
K
S
A
S
M
L
V
HGIG
E
A
K
-----
T
-
M
A
---
Q
RRN----T
P
L
---
E
D
-
L
K
-KIDDN
D
A
V
T
E
A
F
G
Y
-
Y
FNAD
G
---
E
V
V
H
---
K
----
V
H
S
--VGMQLDDIDAIP
D
I
I
A
VAGGS
S
K
A
E
A
I
E
A
Y
F
KK-P-R-
N
T
V
L
V
TDE
G
A
A
K
K
L
LRDE
1
PsiBlast_PDB
92.62
100%
-98
- C3 -
3BXE
1
CGGR_BACSU
A:
[8-255]
--------------------------------------------------------------------------------------------
G
L
T
L
L
E
K
T
L
K
E
R
L
N
L
K
D
A
I
I
V
S
G
D
S
D
Q
S
P
W
V
K
K
E
M
G
R
A
A
V
A
C
M
K
K
R
F
-
S
G
K
-
N
I
V
A
V
T
G
G
T
T
I
E
A
V
A
E
M
M
-
T
P
D
S
-
K
N
R
E
L
L
F
V
P
A
R
G
G
L
G
E
--
D
-
V
K
N
--
Q
--
A
N
T
I
C
A
H
M
A
E
K
A
-
S
G
T
Y
R
L
L
F
V
P
G
Q
L
-
S
Q
G
-
A
Y
-
S
S
I
I
E
-
E
P
S
V
K
E
V
L
N
T
I
K
S
A
S
M
L
V
H
G
I
G
E
A
K
-----
T
-
M
A
---
Q
R
R
N
----
T
P
L
---
E
D
-
L
K
-
K
I
D
D
N
D
A
V
T
E
A
F
G
Y
-
Y
F
N
A
D
G
---
E
V
V
H
---
K
----
V
H
S
--
V
G
M
Q
L
D
D
I
D
A
I
P
D
I
I
A
V
A
G
G
S
S
K
A
E
A
I
E
A
Y
F
K
K
-
P
-
R
-
N
T
V
L
V
T
D
E
G
A
A
K
K
L
L
R
D
E
21
PsiBlast_CBE
92.58
100%
-96
- C3 -
3BXH
2
CGGR_BACSU
B:
[4-253]
----------------------------------------------------------------------------------------
K
D
V
L
G
L
T
L
L
E
K
T
L
K
E
R
L
N
L
K
D
A
I
I
V
S
G
D
S
D
Q
S
P
W
V
K
K
E
M
G
R
A
A
V
A
C
M
K
K
R
F
-
S
G
K
-
N
I
V
A
V
T
G
G
T
T
I
E
A
V
A
E
M
M
-
T
P
D
S
-
K
N
R
E
L
L
F
V
P
A
R
G
G
L
G
E
--
D
-
V
K
N
--
Q
--
A
N
T
I
C
A
H
M
A
E
K
A
-
S
G
T
Y
R
L
L
F
V
P
G
Q
L
-
S
Q
G
-
A
Y
-
S
S
I
I
E
-
E
P
S
V
K
E
V
L
N
T
I
K
S
A
S
M
L
V
H
G
I
G
E
A
K
-----
T
-
M
A
---
Q
R
R
N
----
T
P
L
---
E
D
-
L
K
-
K
I
D
D
N
D
A
V
T
E
A
F
G
Y
-
Y
F
N
A
D
G
---
E
V
V
H
---
K
----
V
H
S
--
V
G
M
Q
L
D
D
I
D
A
I
P
D
I
I
A
V
A
G
G
S
S
K
A
E
A
I
E
A
Y
F
K
K
-
P
-
R
-
N
T
V
L
V
T
D
E
G
A
A
K
K
L
L
R
--
23
PsiBlast_CBE
92.19
100%
-101
- C3 -
3BXF
5
CGGR_BACSU
B:
[9-253]
---------------------------------------------------------------------------------------------
L
T
L
L
E
K
T
L
K
E
R
L
N
L
K
D
A
I
I
V
S
G
D
S
D
Q
S
P
W
V
K
K
E
M
G
R
A
A
V
A
C
M
K
K
R
F
-
S
G
K
-
N
I
V
A
V
T
G
G
T
T
I
E
A
V
A
E
M
M
-
T
P
D
S
-
K
N
R
E
L
L
F
V
P
A
R
G
G
L
G
E
--
D
-
V
K
N
--
Q
--
A
N
T
I
C
A
H
M
A
E
K
A
-
S
G
T
Y
R
L
L
F
V
P
G
Q
L
-
S
Q
G
-
A
Y
-
S
S
I
I
E
-
E
P
S
V
K
E
V
L
N
T
I
K
S
A
S
M
L
V
H
G
I
G
E
A
K
-----
T
-
M
A
---
Q
R
R
N
----
T
P
L
---
E
D
-
L
K
-
K
I
D
D
N
D
A
V
T
E
A
F
G
Y
-
Y
F
N
A
D
G
---
E
V
V
H
---
K
----
V
H
S
--
V
G
M
Q
L
D
D
I
D
A
I
P
D
I
I
A
V
A
G
G
S
S
K
A
E
A
I
E
A
Y
F
K
K
-
P
-
R
-
N
T
V
L
V
T
D
E
G
A
A
K
K
L
L
R
--
2
PsiBlast_PDB
92.18
100%
-104
- C3 -
3BXF
2
CGGR_BACSU
A:
[4-253]
----------------------------------------------------------------------------------------
K
D
V
L
G
L
T
L
L
E
K
T
L
K
E
R
L
N
L
K
D
A
I
I
V
S
G
D
S
D
Q
S
P
W
V
K
K
E
M
G
R
A
A
V
A
C
M
K
K
R
F
-
S
G
K
-
N
I
V
A
V
T
G
G
T
T
I
E
A
V
A
E
M
M
-
T
P
D
S
-
K
N
R
E
L
L
F
V
P
A
R
G
G
L
G
E
--
D
-
V
K
N
--
Q
--
A
N
T
I
C
A
H
M
A
E
K
A
-
S
G
T
Y
R
L
L
F
V
P
G
Q
L
-
S
Q
G
-
A
Y
-
S
S
I
I
E
-
E
P
S
V
K
E
V
L
N
T
I
K
S
A
S
M
L
V
H
G
I
G
E
A
K
-----
T
-
M
A
---
Q
R
R
N
----
T
P
L
---
E
D
-
L
K
-
K
I
D
D
N
D
A
V
T
E
A
F
G
Y
-
Y
F
N
A
D
G
---
E
V
V
H
---
K
----
V
H
S
--
V
G
M
Q
L
D
D
I
D
A
I
P
D
I
I
A
V
A
G
G
S
S
K
A
E
A
I
E
A
Y
F
K
K
-
P
-
R
-
N
T
V
L
V
T
D
E
G
A
A
K
K
L
L
R
--
3
PsiBlast_PDB
91.91
100%
-95
- C3 -
3BXG
1
CGGR_BACSU
A:
[8-254]
--------------------------------------------------------------------------------------------
G
L
T
L
L
E
K
T
L
K
E
R
L
N
L
K
D
A
I
I
V
S
G
D
S
D
Q
S
P
W
V
K
K
E
M
G
R
A
A
V
A
C
M
K
K
R
F
-
S
G
K
-
N
I
V
A
V
T
G
G
T
T
I
E
A
V
A
E
M
M
-
T
P
D
S
-
K
N
R
E
L
L
F
V
P
A
R
G
G
L
G
E
--
D
-
V
K
N
--
Q
--
A
N
T
I
C
A
H
M
A
E
K
A
-
S
G
T
Y
R
L
L
F
V
P
G
Q
L
-
S
Q
G
-
A
Y
-
S
S
I
I
E
-
E
P
S
V
K
E
V
L
N
T
I
K
S
A
S
M
L
V
H
G
I
G
E
A
K
-----
T
-
M
A
---
Q
R
R
N
----
T
P
L
---
E
D
-
L
K
-
K
I
D
D
N
D
A
V
T
E
A
F
G
Y
-
Y
F
N
A
D
G
---
E
V
V
H
---
K
----
V
H
S
--
V
G
M
Q
L
D
D
I
D
A
I
P
D
I
I
A
V
A
G
G
S
S
K
A
E
A
I
E
A
Y
F
K
K
-
P
-
R
-
N
T
V
L
V
T
D
E
G
A
A
K
K
L
L
R
D
-
5
PsiBlast_PDB
91.79
96%
-102
- C3 -
2OKG
3
CGGR_BACSU
A:
[4-253]
----------------------------------------------------------------------------------------
K
D
V
L
G
L
T
L
L
E
K
T
L
K
E
R
L
N
L
K
D
A
I
I
V
S
G
D
S
D
Q
S
P
W
V
K
K
E
M
G
R
A
A
V
A
C
M
K
K
R
F
-
S
G
K
-
N
I
V
A
V
T
G
G
T
T
I
E
A
V
A
E
M
M
-
T
P
D
S
-
K
N
R
E
L
L
F
V
P
A
R
G
G
L
G
------
K
N
--
Q
--
A
N
T
I
C
A
H
M
A
E
K
A
-
S
G
T
Y
R
L
L
F
V
P
G
Q
L
-
S
Q
G
-
A
Y
-
S
S
I
I
E
-
E
P
S
V
K
E
V
L
N
T
I
K
S
A
S
M
L
V
H
G
I
G
E
A
K
-----
T
-
M
A
---
Q
R
R
N
----
T
P
L
---
E
D
-
L
K
-
K
I
D
D
N
D
A
V
T
E
A
F
G
Y
-
Y
F
N
A
D
G
---
E
V
V
H
---
K
----
V
H
S
--
V
G
M
Q
L
D
D
I
D
A
I
P
D
I
I
A
V
A
G
G
S
S
K
A
E
A
I
E
A
Y
F
K
K
-
P
-
R
-
N
T
V
L
V
T
D
E
G
A
A
K
K
L
L
R
--
4
PsiBlast_PDB
91.63
100%
-98
- C3 -
3BXH
2
CGGR_BACSU
A:
[8-255]
--------------------------------------------------------------------------------------------
G
L
T
L
L
E
K
T
L
K
E
R
L
N
L
K
D
A
I
I
V
S
G
D
S
D
Q
S
P
W
V
K
K
E
M
G
R
A
A
V
A
C
M
K
K
R
F
-
S
G
K
-
N
I
V
A
V
T
G
G
T
T
I
E
A
V
A
E
M
M
-
T
P
D
S
-
K
N
R
E
L
L
F
V
P
A
R
G
G
L
G
E
--
D
-
V
K
N
--
Q
--
A
N
T
I
C
A
H
M
A
E
K
A
-
S
G
T
Y
R
L
L
F
V
P
G
Q
L
-
S
Q
G
-
A
Y
-
S
S
I
I
E
-
E
P
S
V
K
E
V
L
N
T
I
K
S
A
S
M
L
V
H
G
I
G
E
A
K
-----
T
-
M
A
---
Q
R
R
N
----
T
P
L
---
E
D
-
L
K
-
K
I
D
D
N
D
A
V
T
E
A
F
G
Y
-
Y
F
N
A
D
G
---
E
V
V
H
---
K
----
V
H
S
--
V
G
M
Q
L
D
D
I
D
A
I
P
D
I
I
A
V
A
G
G
S
S
K
A
E
A
I
E
A
Y
F
K
K
-
P
-
R
-
N
T
V
L
V
T
D
E
G
A
A
K
K
L
L
R
D
E
22
PsiBlast_CBE
91.41
100%
-98
- C3 -
3BXG
1
CGGR_BACSU
B:
[4-253]
----------------------------------------------------------------------------------------
K
D
V
L
G
L
T
L
L
E
K
T
L
K
E
R
L
N
L
K
D
A
I
I
V
S
G
D
S
D
Q
S
P
W
V
K
K
E
M
G
R
A
A
V
A
C
M
K
K
R
F
-
S
G
K
-
N
I
V
A
V
T
G
G
T
T
I
E
A
V
A
E
M
M
-
T
P
D
S
-
K
N
R
E
L
L
F
V
P
A
R
G
G
L
G
E
--
D
-
V
K
N
--
Q
--
A
N
T
I
C
A
H
M
A
E
K
A
-
S
G
T
Y
R
L
L
F
V
P
G
Q
L
-
S
Q
G
-
A
Y
-
S
S
I
I
E
-
E
P
S
V
K
E
V
L
N
T
I
K
S
A
S
M
L
V
H
G
I
G
E
A
K
-----
T
-
M
A
---
Q
R
R
N
----
T
P
L
---
E
D
-
L
K
-
K
I
D
D
N
D
A
V
T
E
A
F
G
Y
-
Y
F
N
A
D
G
---
E
V
V
H
---
K
----
V
H
S
--
V
G
M
Q
L
D
D
I
D
A
I
P
D
I
I
A
V
A
G
G
S
S
K
A
E
A
I
E
A
Y
F
K
K
-
P
-
R
-
N
T
V
L
V
T
D
E
G
A
A
K
K
L
L
R
--
24
PsiBlast_CBE
91.17
100%
-97
- C3 -
3BXE
1
CGGR_BACSU
B:
[4-253]
----------------------------------------------------------------------------------------
K
D
V
L
G
L
T
L
L
E
K
T
L
K
E
R
L
N
L
K
D
A
I
I
V
S
G
D
S
D
Q
S
P
W
V
K
K
E
M
G
R
A
A
V
A
C
M
K
K
R
F
-
S
G
K
-
N
I
V
A
V
T
G
G
T
T
I
E
A
V
A
E
M
M
-
T
P
D
S
-
K
N
R
E
L
L
F
V
P
A
R
G
G
L
G
E
--
D
-
V
K
N
--
Q
--
A
N
T
I
C
A
H
M
A
E
K
A
-
S
G
T
Y
R
L
L
F
V
P
G
Q
L
-
S
Q
G
-
A
Y
-
S
S
I
I
E
-
E
P
S
V
K
E
V
L
N
T
I
K
S
A
S
M
L
V
H
G
I
G
E
A
K
-----
T
-
M
A
---
Q
R
R
N
----
T
P
L
---
E
D
-
L
K
-
K
I
D
D
N
D
A
V
T
E
A
F
G
Y
-
Y
F
N
A
D
G
---
E
V
V
H
---
K
----
V
H
S
--
V
G
M
Q
L
D
D
I
D
A
I
P
D
I
I
A
V
A
G
G
S
S
K
A
E
A
I
E
A
Y
F
K
K
-
P
-
R
-
N
T
V
L
V
T
D
E
G
A
A
K
K
L
L
R
--
25
PsiBlast_CBE
89.65
96%
-91
- C3 -
2OKG
2
CGGR_BACSU
B:
[4-253]
----------------------------------------------------------------------------------------
K
D
V
L
G
L
T
L
L
E
K
T
L
K
E
R
L
N
L
K
D
A
I
I
V
S
G
D
S
D
Q
S
P
W
V
K
K
E
M
G
R
A
A
V
A
C
M
K
K
R
F
-
S
G
K
-
N
I
V
A
V
T
G
G
T
T
I
E
A
V
A
E
M
M
-
T
P
D
S
-
K
N
R
E
L
L
F
V
P
A
R
G
G
L
G
E
--
D
-
V
K
N
--
Q
--
A
N
T
I
C
A
H
M
A
E
K
A
-
S
G
T
Y
R
L
L
F
V
P
G
Q
L
-
S
Q
G
-
A
Y
-
S
S
I
I
E
-
E
P
S
V
K
E
V
L
N
T
I
K
S
A
S
M
L
V
H
G
I
G
E
A
K
-----
T
-
M
A
---
Q
R
R
N
----
T
P
L
---
E
D
-
L
K
-
K
I
D
D
N
D
A
V
T
E
A
F
G
Y
-
Y
F
N
A
D
G
---
E
V
V
H
---
K
----
V
H
S
--
V
G
M
Q
L
D
D
I
D
A
I
P
D
I
I
A
V
A
G
G
S
S
K
A
E
A
I
E
A
Y
F
K
K
-
P
-
R
-
N
T
V
L
V
T
D
E
G
A
A
K
K
L
L
R
--
47
HHSearch
84.13
96%
-48
- C3 -
2OKG
3
CGGR_BACSU
A:
[8-253]
--------------------------------------------------------------------------------------------
G
L
T
L
L
E
K
T
L
K
E
R
L
N
L
K
D
A
I
I
V
S
G
D
S
D
Q
S
P
W
V
K
K
E
M
G
R
A
A
V
A
C
M
K
K
R
F
-
S
G
K
-
N
I
V
A
V
T
G
G
T
T
I
E
A
V
A
E
M
M
-
T
P
D
S
-
K
N
R
E
L
L
F
V
P
A
R
G
G
L
G
-----
K
-
N
--
Q
--
A
N
T
I
C
A
H
M
A
E
K
A
-
S
G
T
Y
R
L
L
F
V
P
G
Q
L
-
S
Q
G
-
A
Y
-
S
S
I
I
E
-
E
P
S
V
K
E
V
L
N
T
I
K
S
A
S
M
L
V
H
G
I
G
E
A
K
-----
T
-
M
A
----
Q
R
R
----
N
T
P
---
L
E
D
L
K
-
K
I
D
D
N
D
A
V
T
E
A
F
G
Y
-
Y
F
N
A
D
G
---
E
V
V
H
---
K
----
V
H
S
--
V
G
M
Q
L
D
D
I
D
A
I
P
D
I
I
A
V
A
G
G
S
S
K
A
E
A
I
E
A
Y
F
K
K
-
P
-
R
N
T
-
V
L
V
T
D
E
G
A
A
K
K
L
L
R
--
6
PsiBlast_PDB
65.86
43%
14
- C3 -
2O0M
2
?
A:
[95-341]
----------------------------------------------------------------------------------------------
H
Q
I
E
K
E
M
T
Q
Y
F
G
I
Q
R
C
I
V
V
A
G
D
S
D
I
Q
K
K
V
L
S
D
F
G
D
V
L
T
N
T
L
N
L
L
L
P
N
G
E
-
N
T
I
A
V
M
G
G
T
T
M
A
M
V
A
E
N
M
G
S
L
E
T
-
E
K
R
H
N
L
F
V
P
A
R
G
G
I
G
E
--
A
-
V
S
V
--
Q
--
A
N
S
I
S
A
V
M
A
N
K
T
-
G
G
N
Y
R
A
L
Y
V
P
E
Q
L
-
S
R
E
-
T
Y
-
N
S
L
L
Q
-
E
P
S
I
Q
E
V
L
T
L
I
S
H
A
N
C
V
V
H
S
I
G
R
A
L
-----
H
-
M
A
---
A
R
R
K
----
M
S
D
---
D
E
-
M
V
-
M
L
K
Q
K
N
A
V
A
E
S
F
G
Y
-
F
F
D
E
E
G
---
K
V
V
Y
---
K
----
I
P
R
--
I
G
L
Q
L
K
N
L
Q
E
I
P
Y
V
V
A
I
A
G
G
K
T
K
A
K
A
I
R
A
Y
M
K
N
A
P
-
K
-
Q
T
W
L
I
T
D
E
A
A
A
N
E
I
L
K
--
29
Fugue
63.51
18%
-61
- C3 -
2W48
3
SORC_KLEPN
A:
[4-315]
----------------
S
D
D
I
R
L
I
V
K
I
A
Q
L
Y
Y
E
Q
D
M
T
Q
A
Q
I
A
R
E
L
G
I
Y
R
T
T
I
S
R
L
L
K
R
G
R
E
Q
G
I
V
T
I
A
I
N
Y
-------------------
D
Y
N
E
N
L
W
L
E
Q
Q
L
K
Q
K
F
G
L
K
E
A
V
V
A
S
----
S
E
E
E
Q
L
S
A
M
G
Q
H
G
A
L
L
V
D
R
L
L
-
E
P
G
-
D
I
I
G
F
S
W
G
R
A
V
R
S
L
V
E
N
L
-
P
Q
R
S
-
Q
S
R
Q
V
I
C
V
P
I
I
G
G
P
S
G
--
K
-
L
E
S
--
R
YH
V
N
T
L
T
Y
G
A
A
A
R
L
-
K
A
E
S
H
L
A
D
F
P
A
L
L
D
N
P
L
-
I
R
-
N
G
I
M
Q
-
S
Q
H
F
K
T
I
S
S
Y
W
D
S
L
D
V
A
L
V
G
I
G
S
P
A
-----
I
-
R
D
---
G
A
N
W
----
H
A
F
YG
S
E
E
-
S
D
-
D
L
N
A
R
H
V
A
G
D
I
C
S
R
-
F
Y
D
I
N
G
---
G
L
V
D
TNM
S
----
E
K
T
--
L
S
I
E
M
A
K
L
R
Q
A
R
Y
S
I
G
I
A
M
G
E
E
K
Y
S
G
I
L
G
A
L
H
G
-
R
-
Y
-
I
N
C
L
V
T
N
R
E
T
A
E
L
L
L
K
--
38
HHSearch
63.34
19%
-59
* C3 *
2W48
3
SORC_KLEPN
A:
[8-315]
-------------------
R
L
I
V
K
I
A
Q
L
Y
Y
E
-
Q
D
M
T
Q
A
Q
I
A
R
E
L
G
I
Y
R
T
T
I
S
R
L
L
K
R
G
R
E
Q
G
I
V
T
I
A
I
N
Y
----------------
D
Y
---
N
E
N
L
W
L
E
Q
Q
L
K
Q
K
F
G
L
K
E
A
V
V
A
S
S
----
E
E
E
Q
L
S
A
M
G
Q
H
G
A
L
L
V
D
R
L
L
-
E
P
G
-
D
I
I
G
F
S
W
G
R
A
V
R
S
L
V
E
N
L
-
P
Q
R
S
-
Q
S
R
Q
V
I
C
V
P
I
I
G
G
P
S
G
KL
E
-
S
R
Y
--
H
--
V
N
T
L
T
Y
G
A
A
A
R
L
-
K
A
E
S
H
L
A
D
F
P
A
L
L
-
D
N
P
L
I
R
-
N
G
I
M
Q
-
S
Q
H
F
K
T
I
S
S
Y
W
D
S
L
D
V
A
L
V
G
I
G
S
P
A
-----
I
-
R
D
GA-
N
W
H
A
----
F
Y
G
---
S
E
E
S
D
-
D
L
N
A
R
H
V
A
G
D
I
C
S
R
-
F
Y
D
I
N
G
---
G
L
V
D
---
T
NMS-
E
K
T
--
L
S
I
E
M
A
K
L
R
Q
A
R
Y
S
I
G
I
A
M
G
E
E
K
Y
S
G
I
L
G
A
L
H
G
-
R
-
Y
I
N
-
C
L
V
T
N
R
E
T
A
E
L
L
L
K
--
37
HHSearch
61.79
43%
21
- C3 -
2O0M
2
?
A:
[95-341]
----------------------------------------------------------------------------------------------
H
Q
I
E
K
E
M
T
Q
Y
F
G
I
Q
R
C
I
V
V
A
G
D
S
D
I
Q
K
K
V
L
S
D
F
G
D
V
L
T
N
T
L
N
L
L
L
-
P
N
G
E
N
T
I
A
V
M
G
G
T
T
M
A
M
V
A
E
N
M
-
G
S
L
E
T
E
K
R
H
N
L
F
V
P
A
R
G
G
I
G
E
A-
V
--
S
V
--
Q
--
A
N
S
I
S
A
V
M
A
N
K
T
-
G
G
N
Y
R
A
L
Y
V
P
E
Q
L
-
S
R
E
-
T
Y
-
N
S
L
L
Q
-
E
P
S
I
Q
E
V
L
T
L
I
S
H
A
N
C
V
V
H
S
I
G
R
A
L
-----
H
-
M
A
----
A
R
R
----
K
M
S
---
D
D
E
M
V
-
M
L
K
Q
K
N
A
V
A
E
S
F
G
Y
-
F
F
D
E
E
G
---
K
V
V
Y
---
K
----
I
P
R
--
I
G
L
Q
L
K
N
L
Q
E
I
P
Y
V
V
A
I
A
G
G
K
T
K
A
K
A
I
R
A
Y
M
K
N
-
A
P
K
Q
T
-
W
L
I
T
D
E
A
A
A
N
E
I
L
K
--
8
PsiBlast_PDB
58.90
26%
-40
- C3 -
3KV1
5
?
A:
[12-260]
------------------------------------------------------------------------------------------------
L
E
Q
K
L
V
E
K
F
N
L
K
R
A
L
I
-
S
L
D
Q
P
N
T
N
E
Q
R
K
Q
V
A
A
L
V
S
S
Y
L
N
N
N
L
-
Q
E
G
-
M
A
V
A
V
G
Q
G
Q
N
V
A
A
V
A
D
H
A
-
G
I
V
T
-
Q
-
R
N
A
R
F
V
S
A
I
G
G
T
H
-----
I
I
N
-----
A
D
H
I
C
R
R
L
A
K
K
Y
-
G
G
S
S
E
T
L
Y
A
P
A
Y
V
-
N
D
P
-
S
L
R
S
A
F
M
E
-
H
A
T
I
K
E
T
L
S
Q
A
R
K
A
E
F
A
L
V
G
I
G
D
M
D
-----
E
-
N
S
---
H
M
V
K
L
GFF
T
P
K
---
E
F
-
V
E
-
A
R
L
N
D
G
I
V
G
D
I
G
G
F
D
F
F
K
L
D
G
TDA
D
T
L
M
---
R
----
G
R
V
--
I
G
L
E
M
E
D
L
R
Q
I
P
N
V
V
A
M
A
S
E
S
R
K
A
L
S
I
M
G
A
L
R
T
-
G
-
V
-
I
D
V
L
A
T
S
V
S
C
A
M
A
L
L
---
39
HHSearch
58.24
22%
-55
- C3 -
4L5J
1
LSRR_ECOLI
A:
[17-317]
-------------------
E
E
Q
V
A
R
I
A
W
F
Y
Y
H
D
G
L
T
Q
S
E
I
S
D
R
L
G
L
T
R
L
K
V
S
R
L
L
E
K
G
H
Q
S
G
I
I
R
V
Q
I
N
S
----------------
R
F
---
E
G
C
L
E
Y
E
T
Q
L
R
R
Q
F
S
L
Q
H
V
R
V
I
P
G
L
A
D
--
A
D
V
G
G
R
L
G
I
G
A
A
H
M
L
M
S
L
L
-
Q
P
Q
-
Q
M
L
A
I
G
F
G
E
A
T
M
N
T
L
Q
R
L
-
S
G
F
I
-
S
S
Q
Q
I
R
L
V
T
L
S
G
G
V
G
S
Y-
M
-
T
G
I
-------------
G
Q
L
N
A
A
C
S
V
N
I
I
P
A
P
L
R
A
-
S
S
A
D
I
A
-
R
T
L
K
N
-
E
N
C
V
K
D
V
L
L
A
A
Q
A
A
D
V
A
I
V
G
I
G
A
V
S
-----
Q
Q
D
D
A
T
I
I
R
S
G
----
Y
I
S
---
Q
G
E
Q
L
-
M
I
G
R
K
G
A
V
G
D
I
L
G
Y
-
F
F
D
A
K
G
---
D
V
V
T
---
N
I
K
I
H
N
E
L
--
I
G
L
P
L
S
A
L
K
T
I
P
V
R
V
G
V
A
G
G
E
N
K
A
E
A
I
A
A
A
M
K
G
-
G
-
Y
I
N
-
A
L
V
T
D
Q
D
T
A
A
A
I
L
R
--
43
HHSearch
58.05
25%
-28
- C3 -
3KV1
5
?
A:
[9-262]
---------------------------------------------------------------------------------------------
S
V
Q
L
E
Q
K
L
V
E
K
F
N
L
K
R
A
L
I
S
L
D
Q
P
N
T
-
N
E
Q
R
K
Q
V
A
A
L
V
S
S
Y
L
N
N
N
L
-
Q
E
G
-
M
A
V
A
V
G
Q
G
Q
N
V
A
A
V
A
D
H
A
-
G
I
V
--
T
Q
R
N
A
R
F
V
S
A
I
G
G
T
H
------
I
I
--
N
--
A
D
H
I
C
R
R
L
A
K
K
Y
-
G
G
S
S
E
T
L
Y
A
P
A
Y
V
-
N
D
P
S
L
R
-
S
A
F
M
E
-
H
A
T
I
K
E
T
L
S
Q
A
R
K
A
E
F
A
L
V
G
I
G
D
M
D
-----
E
-
N
S
H
M
-
V
K
L
G
----
F
F
T
---
P
K
E
F
V
E
A
R
L
N
D
G
I
V
G
D
I
G
G
F
D
F
F
K
L
D
G
---
T
D
A
D
---
T
LMR-
G
R
V
--
I
G
L
E
M
E
D
L
R
Q
I
P
N
V
V
A
M
A
S
E
S
R
K
A
L
S
I
M
G
A
L
R
T
-
G
-
V
I
D
-
V
L
A
T
S
V
S
C
A
M
A
L
L
N
L
-
42
HHSearch
56.88
20%
-39
- C3 -
3EFB
-
?
A:
[13-266]
---------------------------------------------------------------------------------------------
N
L
W
L
E
Q
Q
L
K
Q
K
F
G
L
K
D
V
V
V
V
S
G
N
D
E
D
E
E
T
Q
L
A
M
M
G
L
H
G
A
Q
L
L
D
R
L
L
-
E
P
G
-
D
I
V
G
F
S
W
G
R
A
V
S
A
L
V
E
N
L
-
P
Q
A
G
-
Q
S
R
Q
L
I
C
V
P
I
I
G
G
P
S
G
K-
L
E
S
R
Y
--
H
--
V
N
T
L
T
Y
S
A
A
A
K
L
-
K
G
E
S
H
L
A
D
F
P
A
L
L
-
D
N
P
L
I
R
-
N
G
I
M
Q
-
S
Q
H
F
K
T
I
S
A
Y
W
D
N
L
D
I
A
L
V
G
I
G
S
P
----------------
A
----
F
Y
G
---
G
E
E
S
D
-
D
L
N
A
R
Q
V
A
G
D
I
C
S
R
-
F
F
D
I
H
G
---
A
M
V
E
T
NM
S
----
E
K
T
--
L
S
I
E
M
N
K
L
K
Q
A
R
Y
S
I
G
I
A
M
S
E
E
K
Y
S
G
I
I
G
A
L
R
G
-
K
-
Y
I
N
-
C
L
V
T
N
S
S
T
A
E
L
L
L
K
--
13
PsiBlast_PDB
55.29
24%
-53
- C3 -
4L4Z
1
LSRR_ECOLI
A:
[24-265]
-------------------------------------------------------------------------------------------------
E
T
Q
L
R
R
Q
F
S
L
Q
H
V
R
V
I
P
G
L
A
D
A
D
--
V
G
G
R
L
G
I
G
A
A
H
M
L
M
S
L
L
-
Q
P
Q
-
Q
M
L
A
I
G
F
G
E
A
T
M
N
T
L
Q
R
L
-
S
G
F
I
-
S
S
Q
Q
I
R
L
V
T
L
S
G
G
V
G
S
--
Y
-
M
T
G
IG
Q
--
L
N
A
A
C
----------
S
V
N
I
I
P
A
P
L
R
A
-
S
S
A
-
D
I
-
A
R
T
L
K
N
E
N
C
V
K
D
V
L
L
A
A
Q
A
A
D
V
A
I
V
G
I
G
A
V
S
QQDDA
T
-
I
I
---
R
S
G
Y
----
I
S
Q
---
G
E
-
Q
L
-
M
I
G
R
K
G
A
V
G
D
I
L
G
Y
-
F
F
D
A
K
G
---
D
V
V
T
NI-
K
----
I
H
N
E
L
I
G
L
P
L
S
A
L
K
T
I
P
V
R
V
G
V
A
G
G
E
N
K
A
E
A
I
A
A
A
M
K
G
-
G
-
Y
-
I
N
A
L
V
T
D
Q
D
T
A
A
A
I
L
R
--