@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu34550: (2016-07-28 )
MKAVIFDLDGVITDTAEYHFLAWKHIAEQIDIPFDRDMNERLKGISREESLESILIFGGAETKYTNAEKQELMHRKNRDYQMLISKLTPEDLLPGIGRLLCQLKNENIKIGLASSSRNAPKILRRLAIIDDFHAIVDPTTLAKGKPDPDIFLTAAAMLDVSPADCAAIEDAEAGISAIKSAGMFAVGVGQGQPMLGADLVVRQTSDLTLELLHEEWEQYRIRESIP
Atome Classification :
(27 SA)
.........10........20........30..-..-....40........50........60........70.......--.80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.----.--.....200........210.......220....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
K
A
V
I
F
DLDGVITDTAEY
H
F
L
A
W
K
H
I
A
E
QIDIP-FD-R
D
M
N
E
R
L
KGI
S
R
E
E
S
L
E
S
I
L
I
FGGAETKYT
N
A
E
K
Q
E
L
M
H
RKNR--
D
Y
Q
M
L
I
S
KL
T
P
E
D
L
L
P
G
I
G
R
L
L
C
Q
LKNE
N
I
K
I
G
LASSSR
N
A
P
K
I
L
R
R
L
A
I
I
D
D
F
H
A
IVDPTTLAKGKPDP
D
I
F
L
T
A
A
A
M
LDVSPADCAAI
E
D
A
E
A
G
I
S
A
I
K
SA
G
M
F
A
V
GVGQGQP----M--LG
A
D
L
V
-
V
RQTS
D
L
T
L
E
L
L
H
E
E
W
E
Q
Y
R
IRESIP
42
HHSearch
97.63
100%
-156
- C1 -
3NAS
-
PGMB_BACSU
A:
[1-223]
L
K
A
V
I
F
D
L
D
G
V
I
T
D
T
A
E
Y
H
F
L
A
W
K
H
I
A
E
Q
I
D
I
P
-
F
D
-
R
D
M
N
E
R
L
K
G
I
S
R
E
E
S
L
E
S
I
L
I
F
G
G
A
E
T
K
Y
T
N
A
E
K
Q
E
L
M
H
R
K
N
R
--
D
Y
Q
M
L
I
S
K
L
T
P
E
D
L
L
P
G
I
G
R
L
L
C
Q
L
K
N
E
N
I
K
I
G
L
A
S
S
S
R
N
A
P
K
I
L
R
R
L
A
I
I
D
D
F
H
A
I
V
D
P
---------
P
D
I
F
L
T
A
A
A
M
L
D
V
S
P
A
D
C
A
A
I
E
D
A
E
A
G
I
S
A
I
K
S
A
G
M
F
A
V
G
V
G
-------------
A
D
L
V
-
V
R
Q
T
S
D
L
T
L
E
L
L
H
E
E
W
E
Q
Y
R
I
R
E
---
1
PsiBlast_PDB
96.76
96%
-156
- C1 -
3NAS
-
PGMB_BACSU
A:
[1-223]
L
K
A
V
I
F
D
L
D
G
V
I
T
D
T
A
E
Y
H
F
L
A
W
K
H
I
A
E
Q
I
D
I
P
-
F
D
-
R
D
M
N
E
R
L
K
G
I
S
R
E
E
S
L
E
S
I
L
I
F
G
G
A
E
T
K
Y
T
N
A
E
K
Q
E
L
M
H
R
K
N
R
--
D
Y
Q
M
L
I
S
K
L
T
P
E
D
L
L
P
G
I
G
R
L
L
C
Q
L
K
N
E
N
I
K
I
G
L
A
S
S
S
R
N
A
P
K
I
L
R
R
L
A
I
I
D
D
F
H
A
I
V
D
P
---------
P
D
I
F
L
T
A
A
A
M
L
D
V
S
P
A
D
C
A
A
I
E
D
A
E
A
G
I
S
A
I
K
S
A
G
M
F
A
V
G
V
G
-------------
A
D
L
V
-
V
R
Q
T
S
D
L
T
L
E
L
L
H
E
E
W
E
Q
Y
R
I
R
E
---
20
PsiBlast_PDB
84.47
47%
-156
- C1 -
4G9B
9
PGMB_ECOLI
A:
[5-219]
L
Q
G
V
I
F
D
L
D
G
V
I
T
D
T
A
H
L
H
F
Q
A
W
Q
Q
I
A
A
E
I
G
I
S
-
I
D
-
A
Q
F
N
E
S
L
K
G
I
S
R
D
E
S
L
R
R
I
L
Q
H
G
G
K
E
G
D
F
N
S
Q
E
R
A
Q
L
A
Y
R
K
N
L
--
L
Y
V
H
S
L
R
E
L
T
V
N
A
V
L
P
G
I
R
S
L
L
A
D
L
R
A
Q
Q
I
S
V
G
L
A
S
V
S
L
N
A
P
T
I
L
A
A
L
E
L
R
E
F
F
T
F
C
A
D
A
S
Q
L
K
N
S
K
P
D
P
E
I
F
L
A
A
C
A
G
L
G
V
P
P
Q
A
C
I
G
I
E
D
A
Q
A
G
I
D
A
I
N
A
S
G
M
R
S
V
G
I
G
A
G
------
L
--
T
G
A
Q
L
L
-
L
P
S
T
E
S
L
T
W
P
R
L
S
A
F
W
Q
---------
21
PsiBlast_CBE
80.07
47%
-114
- C1 -
4GIB
5
?
B:
[26-247]
I
E
A
F
I
F
D
L
D
G
V
I
T
D
T
A
Y
Y
H
Y
M
A
W
R
K
L
A
H
K
V
G
I
D
-
I
D
-
T
K
F
N
E
S
L
K
G
I
S
R
M
E
S
L
D
R
I
L
E
F
G
N
K
K
Y
S
F
S
E
E
E
K
V
R
M
A
E
E
K
N
N
--
Y
Y
V
S
L
I
D
E
I
T
S
N
D
I
L
P
G
I
E
S
L
L
I
D
V
K
S
N
N
I
K
I
G
L
S
S
A
S
K
N
A
I
N
V
L
N
H
L
G
I
S
D
K
F
D
F
I
A
D
A
G
K
C
K
N
N
K
P
H
P
E
I
F
L
M
S
A
K
G
L
N
V
N
P
Q
N
C
I
G
I
E
D
A
S
A
G
I
D
A
I
N
S
A
N
M
F
S
V
G
V
G
N
Y
E
N
----
L
--
K
K
A
N
L
V
-
V
D
S
T
N
Q
L
K
F
E
Y
I
Q
E
K
Y
N
E
Y
I
V
R
----
2
PsiBlast_PDB
79.14
47%
-108
- C1 -
4GIB
6
?
A:
[26-248]
I
E
A
F
I
F
D
L
D
G
V
I
T
D
T
A
Y
Y
H
Y
M
A
W
R
K
L
A
H
K
V
G
I
D
-
I
D
-
T
K
F
N
E
S
L
K
G
I
S
R
M
E
S
L
D
R
I
L
E
F
G
N
K
K
Y
S
F
S
E
E
E
K
V
R
M
A
E
E
K
N
N
--
Y
Y
V
S
L
I
D
E
I
T
S
N
D
I
L
P
G
I
E
S
L
L
I
D
V
K
S
N
N
I
K
I
G
L
S
S
A
S
K
N
A
I
N
V
L
N
H
L
G
I
S
D
K
F
D
F
I
A
D
A
G
K
C
K
N
N
K
P
H
P
E
I
F
L
M
S
A
K
G
L
N
V
N
P
Q
N
C
I
G
I
E
D
A
S
A
G
I
D
A
I
N
S
A
N
M
F
S
V
G
V
G
N
Y
E
N
----
L
--
K
K
A
N
L
V
-
V
D
S
T
N
Q
L
K
F
E
Y
I
Q
E
K
Y
N
E
Y
I
V
R
R
---
43
HHSearch
79.09
48%
-110
- C1 -
4GIB
6
?
A:
[26-245]
I
E
A
F
I
F
D
L
D
G
V
I
T
D
T
A
Y
Y
H
Y
M
A
W
R
K
L
A
H
K
V
G
I
D
-
I
D
-
T
K
F
N
E
S
L
K
G
I
S
R
M
E
S
L
D
R
I
L
E
F
G
N
K
K
Y
S
F
S
E
E
E
K
V
R
M
A
E
E
K
N
N
--
Y
Y
V
S
L
I
D
E
I
T
S
N
D
I
L
P
G
I
E
S
L
L
I
D
V
K
S
N
N
I
K
I
G
L
S
S
A
S
K
N
A
I
N
V
L
N
H
L
G
I
S
D
K
F
D
F
I
A
D
A
G
K
C
K
N
N
K
P
H
P
E
I
F
L
M
S
A
K
G
L
N
V
N
P
Q
N
C
I
G
I
E
D
A
S
A
G
I
D
A
I
N
S
A
N
M
F
S
V
G
V
G
N
Y
E
N
----
L
--
K
K
A
N
L
V
-
V
D
S
T
N
Q
L
K
F
E
Y
I
Q
E
K
Y
N
E
Y
I
------
7
PsiBlast_PDB
69.71
50%
-26
- C1 -
1ZOL
1
PGMB_LACLA
A:
[2-218]
F
K
A
V
L
F
D
L
D
G
V
I
T
D
T
A
E
Y
H
F
R
A
W
K
A
L
A
E
E
I
G
I
N
G
V
D
-
R
Q
F
N
E
Q
L
K
G
V
S
R
E
D
S
L
Q
K
I
L
D
L
--
A
D
K
K
V
S
A
E
E
F
K
E
L
A
K
R
K
N
D
--
N
Y
V
K
M
I
Q
D
V
S
P
A
D
V
Y
P
G
I
L
Q
L
L
K
D
L
R
S
N
K
I
K
I
A
L
A
S
A
S
K
N
G
P
F
L
L
E
R
M
N
L
T
G
Y
F
D
A
I
A
D
P
A
E
V
A
A
S
K
P
A
P
D
I
F
I
A
A
A
H
A
V
G
V
A
P
S
E
S
I
G
L
E
D
S
Q
A
G
I
Q
A
I
K
D
S
G
A
L
P
I
G
V
G
R
P
E
D
-------
L
G
D
D
I
V
I
V
P
D
T
S
H
Y
T
L
E
F
L
K
E
V
W
L
Q
--------
9
PsiBlast_PDB
69.20
50%
-17
- C1 -
2WHE
1
PGMB_LACLA
A:
[2-218]
F
K
A
V
L
F
D
L
D
G
V
I
T
D
T
A
E
Y
H
F
R
A
W
K
A
L
A
E
E
I
G
I
N
G
V
D
-
R
Q
F
N
E
Q
L
K
G
V
S
R
E
D
S
L
Q
K
I
L
D
L
--
A
D
K
K
V
S
A
E
E
F
K
E
L
A
K
R
K
N
D
--
N
Y
V
K
M
I
Q
D
V
S
P
A
D
V
Y
P
G
I
L
Q
L
L
K
D
L
R
S
N
K
I
K
I
A
L
A
S
A
S
K
N
G
P
F
L
L
E
R
M
N
L
T
G
Y
F
D
A
I
A
D
P
A
E
V
A
A
S
K
P
A
P
D
I
F
I
A
A
A
H
A
V
G
V
A
P
S
E
S
I
G
L
E
D
S
Q
A
G
I
Q
A
I
K
D
S
G
A
L
P
I
G
V
G
R
P
E
D
-------
L
G
D
D
I
V
I
V
P
D
T
S
H
Y
T
L
E
F
L
K
E
V
W
L
Q
--------
14
PsiBlast_PDB
68.07
50%
-15
- C1 -
2WFA
2
PGMB_LACLA
A:
[2-218]
F
K
A
V
L
F
D
L
D
G
V
I
T
D
T
A
E
Y
H
F
R
A
W
K
A
L
A
E
E
I
G
I
N
G
V
D
-
R
Q
F
N
E
Q
L
K
G
V
S
R
E
D
S
L
Q
K
I
L
D
L
--
A
D
K
K
V
S
A
E
E
F
K
E
L
A
K
R
K
N
D
--
N
Y
V
K
M
I
Q
D
V
S
P
A
D
V
Y
P
G
I
L
Q
L
L
K
D
L
R
S
N
K
I
K
I
A
L
A
S
A
S
K
N
G
P
F
L
L
E
R
M
N
L
T
G
Y
F
D
A
I
A
D
P
A
E
V
A
A
S
K
P
A
P
D
I
F
I
A
A
A
H
A
V
G
V
A
P
S
E
S
I
G
L
E
D
S
Q
A
G
I
Q
A
I
K
D
S
G
A
L
P
I
G
V
G
R
P
E
D
-------
L
G
D
D
I
V
I
V
P
D
T
S
H
Y
T
L
E
F
L
K
E
V
W
L
Q
--------
19
PsiBlast_PDB
67.45
49%
-19
- C1 -
3FM9
1
PGMB_LACLA
A:
[2-218]
F
K
A
V
L
F
D
L
D
G
V
I
T
D
P
A
E
Y
H
F
R
A
W
K
A
L
A
E
E
I
G
I
N
G
V
D
-
R
Q
F
N
E
Q
L
K
G
V
S
R
E
D
S
L
Q
K
I
L
D
L
--
A
D
K
K
V
S
A
E
E
F
K
E
L
A
K
R
K
N
D
--
N
Y
V
K
M
I
Q
D
V
S
P
A
D
V
Y
P
G
I
L
Q
L
L
K
D
L
R
S
N
K
I
K
I
A
L
A
S
A
S
K
N
G
P
F
L
L
E
R
M
N
L
T
G
Y
F
D
A
I
A
D
P
A
E
V
A
A
S
K
P
A
P
D
I
F
I
A
A
A
H
A
V
G
V
A
P
S
E
S
I
G
L
E
D
S
Q
A
G
I
Q
A
I
K
D
S
G
A
L
P
I
G
V
G
R
P
E
D
-------
L
G
D
D
I
V
I
V
P
D
T
S
H
Y
T
L
E
F
L
K
E
V
W
L
Q
--------
13
PsiBlast_PDB
67.15
50%
-10
- C1 -
2WF9
3
PGMB_LACLA
A:
[2-218]
F
K
A
V
L
F
D
L
D
G
V
I
T
D
T
A
E
Y
H
F
R
A
W
K
A
L
A
E
E
I
G
I
N
G
V
D
-
R
Q
F
N
E
Q
L
K
G
V
S
R
E
D
S
L
Q
K
I
L
D
L
--
A
D
K
K
V
S
A
E
E
F
K
E
L
A
K
R
K
N
D
--
N
Y
V
K
M
I
Q
D
V
S
P
A
D
V
Y
P
G
I
L
Q
L
L
K
D
L
R
S
N
K
I
K
I
A
L
A
S
A
S
K
N
G
P
F
L
L
E
R
M
N
L
T
G
Y
F
D
A
I
A
D
P
A
E
V
A
A
S
K
P
A
P
D
I
F
I
A
A
A
H
A
V
G
V
A
P
S
E
S
I
G
L
E
D
S
Q
A
G
I
Q
A
I
K
D
S
G
A
L
P
I
G
V
G
R
P
E
D
-------
L
G
D
D
I
V
I
V
P
D
T
S
H
Y
T
L
E
F
L
K
E
V
W
L
Q
--------
5
PsiBlast_PDB
65.54
50%
-13
- C1 -
1Z4N
2
PGMB_LACLA
A:
[2-218]
F
K
A
V
L
F
D
L
D
G
V
I
T
D
T
A
E
Y
H
F
R
A
W
K
A
L
A
E
E
I
G
I
N
G
V
D
-
R
Q
F
N
E
Q
L
K
G
V
S
R
E
D
S
L
Q
K
I
L
D
L
--
A
D
K
K
V
S
A
E
E
F
K
E
L
A
K
R
K
N
D
--
N
Y
V
K
M
I
Q
D
V
S
P
A
D
V
Y
P
G
I
L
Q
L
L
K
D
L
R
S
N
K
I
K
I
A
L
A
S
A
S
K
N
G
P
F
L
L
E
R
M
N
L
T
G
Y
F
D
A
I
A
D
P
A
E
V
A
A
S
K
P
A
P
D
I
F
I
A
A
A
H
A
V
G
V
A
P
S
E
S
I
G
L
E
D
S
Q
A
G
I
Q
A
I
K
D
S
G
A
L
P
I
G
V
G
R
P
E
D
-------
L
G
D
D
I
V
I
V
P
D
T
S
H
Y
T
L
E
F
L
K
E
V
W
L
Q
--------
8
PsiBlast_PDB
64.68
50%
-12
- C1 -
2WF5
3
PGMB_LACLA
A:
[2-218]
F
K
A
V
L
F
D
L
D
G
V
I
T
D
T
A
E
Y
H
F
R
A
W
K
A
L
A
E
E
I
G
I
N
G
V
D
-
R
Q
F
N
E
Q
L
K
G
V
S
R
E
D
S
L
Q
K
I
L
D
L
--
A
D
K
K
V
S
A
E
E
F
K
E
L
A
K
R
K
N
D
--
N
Y
V
K
M
I
Q
D
V
S
P
A
D
V
Y
P
G
I
L
Q
L
L
K
D
L
R
S
N
K
I
K
I
A
L
A
S
A
S
K
N
G
P
F
L
L
E
R
M
N
L
T
G
Y
F
D
A
I
A
D
P
A
E
V
A
A
S
K
P
A
P
D
I
F
I
A
A
A
H
A
V
G
V
A
P
S
E
S
I
G
L
E
D
S
Q
A
G
I
Q
A
I
K
D
S
G
A
L
P
I
G
V
G
R
P
E
D
-------
L
G
D
D
I
V
I
V
P
D
T
S
H
Y
T
L
E
F
L
K
E
V
W
L
Q
--------
15
PsiBlast_PDB
64.53
50%
-14
- C1 -
3ZI4
3
PGMB_LACLA
A:
[2-218]
F
K
A
V
L
F
D
L
D
G
V
I
T
D
T
A
E
Y
H
F
R
A
W
K
A
L
A
E
E
I
G
I
N
G
V
D
-
R
Q
F
N
E
Q
L
K
G
V
S
R
E
D
S
L
Q
K
I
L
D
L
--
A
D
K
K
V
S
A
E
E
F
K
E
L
A
K
R
K
N
D
--
N
Y
V
K
M
I
Q
D
V
S
P
A
D
V
Y
P
G
I
L
Q
L
L
K
D
L
R
S
N
K
I
K
I
A
L
A
S
A
S
K
N
G
P
F
L
L
E
R
M
N
L
T
G
Y
F
D
A
I
A
D
P
A
E
V
A
A
S
K
P
A
P
D
I
F
I
A
A
A
H
A
V
G
V
A
P
S
E
S
I
G
L
E
D
S
Q
A
G
I
Q
A
I
K
D
S
G
A
L
P
I
G
V
G
R
P
E
D
-------
L
G
D
D
I
V
I
V
P
D
T
S
H
Y
T
L
E
F
L
K
E
V
W
L
Q
--------
48
HHSearch
64.52
45%
-45
- C1 -
4G9B
9
PGMB_ECOLI
A:
[5-219]
L
Q
G
V
I
F
D
L
D
G
V
I
T
D
T
A
H
L
H
F
Q
A
W
Q
Q
I
A
A
E
I
G
I
S
-
I
D
-
A
Q
F
N
E
S
L
K
G
I
S
R
D
E
S
L
R
R
I
L
Q
H
G
G
K
E
--
G
D
F
N
S
Q
E
R
A
Q
L
A
Y
R
K
N
L
L
Y
V
H
S
L
R
E
L
T
V
N
A
V
L
P
G
I
R
S
L
L
A
D
L
R
A
Q
Q
I
S
V
G
L
A
S
V
S
L
N
A
P
T
I
L
A
A
L
E
L
R
E
F
F
T
F
C
A
D
A
S
Q
L
K
N
S
K
P
D
P
E
I
F
L
A
A
C
A
G
L
G
V
P
P
Q
A
C
I
G
I
E
D
A
Q
A
G
I
D
A
I
N
A
S
G
M
R
S
V
G
I
G
A
G
L
T
GAQL
L
LP
S
T
E
S
L
T
-
W
P
R
L
S
A
F
W
Q
-----------------
18
PsiBlast_PDB
64.21
50%
-8
- C1 -
4C4T
3
PGMB_LACLA
A:
[2-217]
F
K
A
V
L
F
D
L
D
G
V
I
T
D
T
A
E
Y
H
F
R
A
W
K
A
L
A
E
E
I
G
I
N
G
V
D
-
R
Q
F
N
E
Q
L
K
G
V
S
R
E
D
S
L
Q
K
I
L
D
L
--
A
D
K
K
V
S
A
E
E
F
K
E
L
A
K
R
K
N
D
--
N
Y
V
K
M
I
Q
D
V
S
P
A
D
V
Y
P
G
I
L
Q
L
L
K
D
L
R
S
N
K
I
K
I
A
L
A
S
A
S
K
N
G
P
F
L
L
E
R
M
N
L
T
G
Y
F
D
A
I
A
D
P
A
E
V
A
A
S
K
P
A
P
D
I
F
I
A
A
A
H
A
V
G
V
A
P
S
E
S
I
G
L
E
D
S
Q
A
G
I
Q
A
I
K
D
S
G
A
L
P
I
G
V
G
R
P
E
D
-------
L
G
D
D
I
V
I
V
P
D
T
S
H
Y
T
L
E
F
L
K
E
V
W
L
---------
4
PsiBlast_PDB
64.17
50%
-16
- C1 -
1O08
2
PGMB_LACLA
A:
[2-218]
F
K
A
V
L
F
D
L
D
G
V
I
T
D
T
A
E
Y
H
F
R
A
W
K
A
L
A
E
E
I
G
I
N
G
V
D
-
R
Q
F
N
E
Q
L
K
G
V
S
R
E
D
S
L
Q
K
I
L
D
L
--
A
D
K
K
V
S
A
E
E
F
K
E
L
A
K
R
K
N
D
--
N
Y
V
K
M
I
Q
D
V
S
P
A
D
V
Y
P
G
I
L
Q
L
L
K
D
L
R
S
N
K
I
K
I
A
L
A
S
A
S
K
N
G
P
F
L
L
E
R
M
N
L
T
G
Y
F
D
A
I
A
D
P
A
E
V
A
A
S
K
P
A
P
D
I
F
I
A
A
A
H
A
V
G
V
A
P
S
E
S
I
G
L
E
D
S
Q
A
G
I
Q
A
I
K
D
S
G
A
L
P
I
G
V
G
R
P
E
D
-------
L
G
D
D
I
V
I
V
P
D
T
S
H
Y
T
L
E
F
L
K
E
V
W
L
Q
--------
10
PsiBlast_PDB
64.13
50%
-11
- C1 -
2WF7
3
PGMB_LACLA
A:
[2-218]
F
K
A
V
L
F
D
L
D
G
V
I
T
D
T
A
E
Y
H
F
R
A
W
K
A
L
A
E
E
I
G
I
N
G
V
D
-
R
Q
F
N
E
Q
L
K
G
V
S
R
E
D
S
L
Q
K
I
L
D
L
--
A
D
K
K
V
S
A
E
E
F
K
E
L
A
K
R
K
N
D
--
N
Y
V
K
M
I
Q
D
V
S
P
A
D
V
Y
P
G
I
L
Q
L
L
K
D
L
R
S
N
K
I
K
I
A
L
A
S
A
S
K
N
G
P
F
L
L
E
R
M
N
L
T
G
Y
F
D
A
I
A
D
P
A
E
V
A
A
S
K
P
A
P
D
I
F
I
A
A
A
H
A
V
G
V
A
P
S
E
S
I
G
L
E
D
S
Q
A
G
I
Q
A
I
K
D
S
G
A
L
P
I
G
V
G
R
P
E
D
-------
L
G
D
D
I
V
I
V
P
D
T
S
H
Y
T
L
E
F
L
K
E
V
W
L
Q
--------
11
PsiBlast_PDB
64.11
50%
-13
- C1 -
2WF6
3
PGMB_LACLA
A:
[2-218]
F
K
A
V
L
F
D
L
D
G
V
I
T
D
T
A
E
Y
H
F
R
A
W
K
A
L
A
E
E
I
G
I
N
G
V
D
-
R
Q
F
N
E
Q
L
K
G
V
S
R
E
D
S
L
Q
K
I
L
D
L
--
A
D
K
K
V
S
A
E
E
F
K
E
L
A
K
R
K
N
D
--
N
Y
V
K
M
I
Q
D
V
S
P
A
D
V
Y
P
G
I
L
Q
L
L
K
D
L
R
S
N
K
I
K
I
A
L
A
S
A
S
K
N
G
P
F
L
L
E
R
M
N
L
T
G
Y
F
D
A
I
A
D
P
A
E
V
A
A
S
K
P
A
P
D
I
F
I
A
A
A
H
A
V
G
V
A
P
S
E
S
I
G
L
E
D
S
Q
A
G
I
Q
A
I
K
D
S
G
A
L
P
I
G
V
G
R
P
E
D
-------
L
G
D
D
I
V
I
V
P
D
T
S
H
Y
T
L
E
F
L
K
E
V
W
L
Q
--------
12
PsiBlast_PDB
64.02
50%
-10
- C1 -
2WF8
7
PGMB_LACLA
A:
[2-218]
F
K
A
V
L
F
D
L
D
G
V
I
T
D
T
A
E
Y
H
F
R
A
W
K
A
L
A
E
E
I
G
I
N
G
V
D
-
R
Q
F
N
E
Q
L
K
G
V
S
R
E
D
S
L
Q
K
I
L
D
L
--
A
D
K
K
V
S
A
E
E
F
K
E
L
A
K
R
K
N
D
--
N
Y
V
K
M
I
Q
D
V
S
P
A
D
V
Y
P
G
I
L
Q
L
L
K
D
L
R
S
N
K
I
K
I
A
L
A
S
A
S
K
N
G
P
F
L
L
E
R
M
N
L
T
G
Y
F
D
A
I
A
D
P
A
E
V
A
A
S
K
P
A
P
D
I
F
I
A
A
A
H
A
V
G
V
A
P
S
E
S
I
G
L
E
D
S
Q
A
G
I
Q
A
I
K
D
S
G
A
L
P
I
G
V
G
R
P
E
D
-------
L
G
D
D
I
V
I
V
P
D
T
S
H
Y
T
L
E
F
L
K
E
V
W
L
Q
--------
16
PsiBlast_PDB
63.67
50%
-11
- C1 -
4C4R
3
PGMB_LACLA
A:
[2-218]
F
K
A
V
L
F
D
L
D
G
V
I
T
D
T
A
E
Y
H
F
R
A
W
K
A
L
A
E
E
I
G
I
N
G
V
D
-
R
Q
F
N
E
Q
L
K
G
V
S
R
E
D
S
L
Q
K
I
L
D
L
--
A
D
K
K
V
S
A
E
E
F
K
E
L
A
K
R
K
N
D
--
N
Y
V
K
M
I
Q
D
V
S
P
A
D
V
Y
P
G
I
L
Q
L
L
K
D
L
R
S
N
K
I
K
I
A
L
A
S
A
S
K
N
G
P
F
L
L
E
R
M
N
L
T
G
Y
F
D
A
I
A
D
P
A
E
V
A
A
S
K
P
A
P
D
I
F
I
A
A
A
H
A
V
G
V
A
P
S
E
S
I
G
L
E
D
S
Q
A
G
I
Q
A
I
K
D
S
G
A
L
P
I
G
V
G
R
P
E
D
-------
L
G
D
D
I
V
I
V
P
D
T
S
H
Y
T
L
E
F
L
K
E
V
W
L
Q
--------
22
PsiBlast_CBE
63.21
50%
-16
- C1 -
1Z4O
2
PGMB_LACLA
B:
[2-218]
F
K
A
V
L
F
D
L
D
G
V
I
T
D
T
A
E
Y
H
F
R
A
W
K
A
L
A
E
E
I
G
I
N
G
V
D
-
R
Q
F
N
E
Q
L
K
G
V
S
R
E
D
S
L
Q
K
I
L
D
L
--
A
D
K
----
E
E
F
K
E
L
A
K
R
K
N
D
--
N
Y
V
K
M
I
Q
D
V
S
P
A
D
V
Y
P
G
I
L
Q
L
L
K
D
L
R
S
N
K
I
K
I
A
L
A
S
A
S
K
N
G
P
F
L
L
E
R
M
N
L
T
G
Y
F
D
A
I
A
D
P
A
E
V
A
A
S
K
P
A
P
D
I
F
I
A
A
A
H
A
V
G
V
A
P
S
E
S
I
G
L
E
D
S
Q
A
G
I
Q
A
I
K
D
S
G
A
L
P
I
G
V
G
R
P
E
D
-------
L
G
D
D
I
V
I
V
P
D
T
S
H
Y
T
L
E
F
L
K
E
V
W
L
Q
--------
3
PsiBlast_PDB
63.05
50%
-15
- C1 -
1O03
2
PGMB_LACLA
A:
[2-218]
F
K
A
V
L
F
D
L
D
G
V
I
T
D
T
A
E
Y
H
F
R
A
W
K
A
L
A
E
E
I
G
I
N
G
V
D
-
R
Q
F
N
E
Q
L
K
G
V
S
R
E
D
S
L
Q
K
I
L
D
L
--
A
D
K
K
V
S
A
E
E
F
K
E
L
A
K
R
K
N
D
--
N
Y
V
K
M
I
Q
D
V
S
P
A
D
V
Y
P
G
I
L
Q
L
L
K
D
L
R
S
N
K
I
K
I
A
L
A
S
A
S
K
N
G
P
F
L
L
E
R
M
N
L
T
G
Y
F
D
A
I
A
D
P
A
E
V
A
A
S
K
P
A
P
D
I
F
I
A
A
A
H
A
V
G
V
A
P
S
E
S
I
G
L
E
D
S
Q
A
G
I
Q
A
I
K
D
S
G
A
L
P
I
G
V
G
R
P
E
D
-------
L
G
D
D
I
V
I
V
P
D
T
S
H
Y
T
L
E
F
L
K
E
V
W
L
Q
--------
6
PsiBlast_PDB
62.79
50%
-8
- C1 -
1Z4O
2
PGMB_LACLA
A:
[2-218]
F
K
A
V
L
F
D
L
D
G
V
I
T
D
T
A
E
Y
H
F
R
A
W
K
A
L
A
E
E
I
G
I
N
G
V
D
-
R
Q
F
N
E
Q
L
K
G
V
S
R
E
D
S
L
Q
K
I
L
D
L
--
A
D
K
K
V
S
A
E
E
F
K
E
L
A
K
R
K
N
D
--
N
Y
V
K
M
I
Q
D
V
S
P
A
D
V
Y
P
G
I
L
Q
L
L
K
D
L
R
S
N
K
I
K
I
A
L
A
S
A
S
K
N
G
P
F
L
L
E
R
M
N
L
T
G
Y
F
D
A
I
A
D
P
A
-
V
A
A
S
K
P
A
P
D
I
F
I
A
A
A
H
A
V
G
V
A
P
S
E
S
I
G
L
E
D
S
Q
A
G
I
Q
A
I
K
D
S
G
A
L
P
I
G
V
G
R
P
E
D
-------
L
G
D
D
I
V
I
V
P
D
T
S
H
Y
T
L
E
F
L
K
E
V
W
L
Q
--------
17
PsiBlast_PDB
61.81
50%
-10
- C1 -
4C4S
3
PGMB_LACLA
A:
[2-218]
F
K
A
V
L
F
D
L
D
G
V
I
T
D
T
A
E
Y
H
F
R
A
W
K
A
L
A
E
E
I
G
I
N
G
V
D
-
R
Q
F
N
E
Q
L
K
G
V
S
R
E
D
S
L
Q
K
I
L
D
L
-----
K
V
S
A
E
E
F
K
E
L
A
K
R
K
N
D
--
N
Y
V
K
M
I
Q
D
V
S
P
A
D
V
Y
P
G
I
L
Q
L
L
K
D
L
R
S
N
K
I
K
I
A
L
A
S
A
S
K
N
G
P
F
L
L
E
R
M
N
L
T
G
Y
F
D
A
I
A
D
P
A
E
V
A
A
S
K
P
A
P
D
I
F
I
A
A
A
H
A
V
G
V
A
P
S
E
S
I
G
L
E
D
S
Q
A
G
I
Q
A
I
K
D
S
G
A
L
P
I
G
V
G
R
P
E
D
-------
L
G
D
D
I
V
I
V
P
D
T
S
H
Y
T
L
E
F
L
K
E
V
W
L
Q
--------
41
HHSearch
60.76
47%
-22
- C1 -
2WF7
3
PGMB_LACLA
A:
[2-218]
F
K
A
V
L
F
D
L
D
G
V
I
T
D
T
A
E
Y
H
F
R
A
W
K
A
L
A
E
E
I
G
I
N
-
G
V
D
R
Q
F
N
E
Q
L
K
G
V
S
R
E
D
S
L
Q
K
I
L
D
L
A
D
K
K
--
V
S
A
E
E
F
K
E
L
A
K
R
K
N
D
--
N
Y
V
K
M
I
Q
D
V
S
P
A
D
V
Y
P
G
I
L
Q
L
L
K
D
L
R
S
N
K
I
K
I
A
L
A
S
A
S
K
N
G
P
F
L
L
E
R
M
N
L
T
G
Y
F
D
A
I
A
D
P
A
E
V
A
A
S
K
P
A
P
D
I
F
I
A
A
A
H
A
V
G
V
A
P
S
E
S
I
G
L
E
D
S
Q
A
G
I
Q
A
I
K
D
S
G
A
L
P
I
G
V
G
R
P
E
D
----
L
--
G
D
D
I
V
I
-
V
P
D
T
S
H
Y
T
L
E
F
L
K
E
V
W
L
Q
--------
23
PsiBlast_CBE
57.74
50%
1
- C1 -
1Z4N
2
PGMB_LACLA
B:
[2-216]
F
K
A
V
L
F
D
L
D
G
V
I
T
D
T
A
E
Y
H
F
R
A
W
K
A
L
A
E
E
I
G
I
N
G
V
D
-
R
Q
F
N
E
Q
L
K
G
V
S
R
E
D
S
L
Q
K
I
L
D
L
--
A
D
K
K
V
S
A
E
E
F
K
E
L
A
K
R
K
N
D
--
N
Y
V
K
M
I
Q
D
V
S
P
A
D
V
Y
P
G
------------
I
K
I
A
L
A
S
A
S
K
N
G
P
F
L
L
E
R
M
N
L
T
G
Y
F
D
A
I
A
D
P
A
E
V
A
A
S
K
P
A
P
D
I
F
I
A
A
A
H
A
V
G
V
A
P
S
E
S
I
G
L
E
D
S
Q
A
G
I
Q
A
I
K
D
S
G
A
L
P
I
G
V
G
R
P
E
D
-------
L
G
D
D
I
V
I
V
P
D
T
S
H
Y
T
L
E
F
L
K
E
V
W
----------