@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu34680: (2016-07-28 )
MLKPFVFITKPIPEEIEAFIGEHCRYEVWQEDTLPSDVLFEKLKEAEGLLTSGTSGPSINRELLEHAPKLKVVSNQSVGYDNFDIEAMKERGVVGTHTPYTLDDTVADLAFSLILSSARRVAELDRFVRAGKWGTVEEEALFGIDVHHQTLGIIGMGRIGEQAARRAKFGFDMEVLYHNRHRKQETEDSIGVKYAELDTLLEQSDFILLITPLTDETYHMIGEREFKLMKNSAIFVNISRGKTVDEKALIRALQEGWIRGAGLDVYEKEPVTQDNPLLQLDNVTLLPHIGSATAKVRFNMCKQAAENMLAAIQGQTPKNLTREFQ
Atome Classification :
(26 SA)
.........10..-..-....20.--.-......-30.-.-......40........50........60......-..70........80........90........100.......110.......120.......130.---......-------140-..-.......150.......160......-.170.......180-....-...190.......200.......210.......220.......230.......240.......250.......260.......-------270.......280.......290.......300.......310.......320...--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MLK
P
F
V
F
I
TKPI
P
-
E
E
-
I
E
A
F
I
G
E--H-C
R
Y
E
V
W-QED-T-L
P
S
D
V
L
F
E
K
L
K
E
AE
G
L
LTSGTSGPS
I
N
R
E
L
L
E
HA-PK
L
K
V
V
SNQSVGYDNF
D
I
E
A
M
K
ERGVVGTHTPYTLD
D
T
V
A
D
L
A
F
S
L
I
L
S
S
A
R
R
V
A
E
L
D
R
F
V
RAGKW---GTVEE
E
-------
A
---
L
F
-
G
I
D
VH
H
Q
T
L
G
I
I
GMG
R
I
G
E
Q
A
A
R
R
AK-FGF
D
M
E
V
L
Y
HNRHR-KQET-EDSI
G
V
K
Y
A
E
L
D
T
L
LEQS
D
F
I
L
L
I
TPLTD
E
T
Y
H
M
I
G
E
R
E
F
K
LMKN
S
A
I
F
V
N
ISRGKTV
D
E
K
A
L
I
R
A
L
Q
EGWIRGAGLDVYEKE-------PVTQDN
P
L
L
Q
LD
N
V
T
L
LPHIGSAT
A
K
V
R
F
N
M
C
K
Q
A
A
E
N
M
L
A
A
IQGQT
P
K
N
L
T
REFQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
105
Fugue
83.24
31%
-120
- C1 -
1YGY
1
SERA_MYCTU
A:
[3-529]
-
S
L
P
V
V
L
I
A
D
K
L
A
-
P
S
-
T
V
A
A
L
G
D
--
Q
-
V
E
V
R
W
---
V
D
-
G
-
P
D
R
D
K
L
L
A
A
V
P
E
A
D
A
L
L
V
R
--
S
A
T
T
V
D
A
E
V
L
A
A
A
-
P
K
L
K
I
V
A
R
A
G
V
G
L
D
N
V
D
V
D
A
A
T
A
R
G
V
L
V
V
N
A
P
T
S
N
I
H
S
A
A
E
H
A
L
A
L
L
L
A
A
S
R
Q
I
P
A
A
D
A
S
L
R
E
H
T
W
------
K
R
S
-------
S
---
F
S
-
G
T
E
I
F
G
K
T
V
G
V
V
G
L
G
R
I
G
Q
L
V
A
Q
R
I
A
--
A
F
G
A
Y
V
V
A
Y
D
P
Y
V
-
S
P
A
R
-
A
A
Q
L
G
I
E
L
L
S
L
D
D
L
L
A
R
A
D
F
I
S
V
H
L
P
K
T
P
E
T
A
G
L
I
D
K
E
A
L
A
K
T
K
P
G
V
I
I
V
N
A
A
R
G
G
L
V
D
E
A
A
L
A
D
A
I
T
G
G
H
V
R
A
A
G
L
D
V
F
A
T
E
-------
P
-
C
T
D
S
P
L
F
E
L
A
Q
V
V
V
T
P
H
L
G
A
S
T
A
E
A
Q
D
R
A
G
T
D
V
A
E
S
V
R
L
A
L
A
G
E
F
V
P
D
A
V
N
V
G
G
GVVNEEV
A
P
W
L
D
L
V
R
K
L
G
V
L
A
G
V
L
SDELPV
S
L
S
V
Q
V
R
G
ELAAEEV
E
V
L
R
L
S
A
L
R
G
L
F
SAVIEDAVTFVN
A
P
A
L
A
A
E
RG
V
T
A
E
I
C
K
A
SESPNHR
S
V
V
D
V
R
A
V
G
ADG
S
V
V
T
V
S
G
T
L
Y
G
PQLSQKIVQING
R
H
F
D
L
R
AQ
G
I
N
L
I
I
H
Y
V
DRPG
A
L
G
K
I
G
T
L
L
G
T
A
GVNIQ
A
A
Q
L
S
E
D
AEGP
G
A
T
I
L
L
R
L
D
Q
D
V
P
D
D
V
R
T
A
I
A
A
A
VDAY
K
L
E
V
V
D
LS
5
PsiBlast_PDB
81.12
46%
9
- C1 -
2DBQ
8
GYAR_PYRHO
A:
[2-321]
--
K
P
K
V
F
I
T
R
E
I
P
-
E
V
-
G
I
K
M
L
E
D
--
E
-
F
E
V
E
V
W
G
D
E
K
-
E
-
I
P
R
E
I
L
L
K
K
V
K
E
V
D
A
L
V
T
M
L
S
E
--
R
I
D
K
E
V
F
E
N
A
-
P
K
L
R
I
V
A
N
Y
A
V
G
Y
D
N
I
D
I
E
E
A
T
K
R
G
I
Y
V
T
N
T
P
D
V
L
T
D
A
T
A
D
L
A
F
A
L
L
L
A
T
A
R
H
V
V
K
G
D
R
F
V
R
S
G
E
W
K
K
R
G
V
A
W
H
P
-------
K
---
W
F
L
G
Y
D
V
Y
G
K
T
I
G
I
I
G
L
G
R
I
G
Q
A
I
A
K
R
A
K
--
G
F
N
M
R
I
L
Y
Y
S
R
T
R
-
K
E
E
V
-
E
R
E
L
N
A
E
F
K
P
L
E
D
L
L
R
E
S
D
F
V
V
L
A
V
P
L
T
R
E
T
Y
H
L
I
N
E
E
R
L
K
L
M
K
K
T
A
I
L
I
N
I
A
R
G
K
V
V
D
T
N
A
L
V
K
A
L
K
E
G
W
I
A
G
A
G
L
D
V
F
E
E
E
-------
P
Y
Y
N
E
E
-
L
F
K
L
D
N
V
V
L
T
P
H
I
G
S
A
S
F
G
A
R
E
G
M
A
E
L
V
A
K
N
L
I
A
F
K
R
G
E
I
P
P
T
L
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
81.06
47%
4
- C1 -
2DBR
3
GYAR_PYRHO
E:
[1-321]
-
M
K
P
K
V
F
I
T
R
E
I
P
-
E
V
-
G
I
K
M
L
E
D
--
E
-
F
E
V
E
V
W
G
D
E
K
-
E
-
I
P
R
E
I
L
L
K
K
V
K
E
V
D
A
L
V
T
M
L
S
E
--
R
I
D
K
E
V
F
E
N
A
-
P
K
L
R
I
V
A
N
Y
A
V
G
Y
D
N
I
D
I
E
E
A
T
K
R
G
I
Y
V
T
N
T
P
D
V
L
T
D
A
T
A
D
L
A
F
A
L
L
L
A
T
A
R
H
V
V
K
G
D
R
F
V
R
S
G
E
W
KKR
G
V
A
W
H
P
-------
K
---
W
F
L
G
Y
D
V
Y
G
K
T
I
G
I
I
G
L
G
R
I
G
Q
A
I
A
K
R
A
K
--
G
F
N
M
R
I
L
Y
Y
S
R
T
R
-
K
E
E
V
-
E
R
E
L
N
A
E
F
K
P
L
E
D
L
L
R
E
S
D
F
V
V
L
A
V
P
L
T
R
E
T
Y
H
L
I
N
E
E
R
L
K
L
M
K
K
T
A
I
L
I
N
I
A
R
G
K
V
V
D
T
N
A
L
V
K
A
L
K
E
G
W
I
A
G
A
G
L
D
V
F
E
E
E
-------
P
Y
Y
N
E
E
-
L
F
K
L
D
N
V
V
L
T
P
H
I
G
S
A
S
F
G
A
R
E
G
M
A
E
L
V
A
K
N
L
I
A
F
K
R
G
E
I
P
P
T
L
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
79.47
47%
9
- C1 -
2DBR
3
GYAR_PYRHO
D:
[1-321]
-
M
K
P
K
V
F
I
T
R
E
I
P
-
E
V
-
G
I
K
M
L
E
D
--
E
-
F
E
V
E
V
W
G
D
E
K
-
E
-
I
P
R
E
I
L
L
K
K
V
K
E
V
D
A
L
V
T
M
L
S
E
--
R
I
D
K
E
V
F
E
N
A
-
P
K
L
R
I
V
A
N
Y
A
V
G
Y
D
N
I
D
I
E
E
A
T
K
R
G
I
Y
V
T
N
T
P
D
V
L
T
D
A
T
A
D
L
A
F
A
L
L
L
A
T
A
R
H
V
V
K
G
D
R
F
V
R
S
G
E
W
KKR
G
V
A
W
H
P
-------
K
---
W
F
L
G
Y
D
V
Y
G
K
T
I
G
I
I
G
L
G
R
I
G
Q
A
I
A
K
R
A
K
--
G
F
N
M
R
I
L
Y
Y
S
R
T
R
-
K
E
E
V
-
E
R
E
L
N
A
E
F
K
P
L
E
D
L
L
R
E
S
D
F
V
V
L
A
V
P
L
T
R
E
T
Y
H
L
I
N
E
E
R
L
K
L
M
K
K
T
A
I
L
I
N
I
A
R
G
K
V
V
D
T
N
A
L
V
K
A
L
K
E
G
W
I
A
G
A
G
L
D
V
F
E
E
E
-------
P
Y
Y
N
E
E
-
L
F
K
L
D
N
V
V
L
T
P
H
I
G
S
A
S
F
G
A
R
E
G
M
A
E
L
V
A
K
N
L
I
A
F
K
R
G
E
I
P
P
T
L
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
79.46
47%
11
- C1 -
2DBR
3
GYAR_PYRHO
F:
[1-321]
-
M
K
P
K
V
F
I
T
R
E
I
P
-
E
V
-
G
I
K
M
L
E
D
--
E
-
F
E
V
E
V
W
G
D
E
K
-
E
-
I
P
R
E
I
L
L
K
K
V
K
E
V
D
A
L
V
T
M
L
S
E
--
R
I
D
K
E
V
F
E
N
A
-
P
K
L
R
I
V
A
N
Y
A
V
G
Y
D
N
I
D
I
E
E
A
T
K
R
G
I
Y
V
T
N
T
P
D
V
L
T
D
A
T
A
D
L
A
F
A
L
L
L
A
T
A
R
H
V
V
K
G
D
R
F
V
R
S
G
E
W
KKR
G
V
A
W
H
P
-------
K
---
W
F
L
G
Y
D
V
Y
G
K
T
I
G
I
I
G
L
G
R
I
G
Q
A
I
A
K
R
A
K
--
G
F
N
M
R
I
L
Y
Y
S
R
T
R
-
K
E
E
V
-
E
R
E
L
N
A
E
F
K
P
L
E
D
L
L
R
E
S
D
F
V
V
L
A
V
P
L
T
R
E
T
Y
H
L
I
N
E
E
R
L
K
L
M
K
K
T
A
I
L
I
N
I
A
R
G
K
V
V
D
T
N
A
L
V
K
A
L
K
E
G
W
I
A
G
A
G
L
D
V
F
E
E
E
-------
P
Y
Y
N
E
E
-
L
F
K
L
D
N
V
V
L
T
P
H
I
G
S
A
S
F
G
A
R
E
G
M
A
E
L
V
A
K
N
L
I
A
F
K
R
G
E
I
P
P
T
L
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
79.23
47%
6
- C1 -
2DBR
3
GYAR_PYRHO
A:
[1-321]
-
M
K
P
K
V
F
I
T
R
E
I
P
-
E
V
-
G
I
K
M
L
E
D
--
E
-
F
E
V
E
V
W
G
D
E
K
-
E
-
I
P
R
E
I
L
L
K
K
V
K
E
V
D
A
L
V
T
M
L
S
E
--
R
I
D
K
E
V
F
E
N
A
-
P
K
L
R
I
V
A
N
Y
A
V
G
Y
D
N
I
D
I
E
E
A
T
K
R
G
I
Y
V
T
N
T
P
D
V
L
T
D
A
T
A
D
L
A
F
A
L
L
L
A
T
A
R
H
V
V
K
G
D
R
F
V
R
S
G
E
W
K
K
R
G
V
A
W
H
P
-------
K
---
W
F
L
G
Y
D
V
Y
G
K
T
I
G
I
I
G
L
G
R
I
G
Q
A
I
A
K
R
A
K
--
G
F
N
M
R
I
L
Y
Y
S
R
T
R
-
K
E
E
V
-
E
R
E
L
N
A
E
F
K
P
L
E
D
L
L
R
E
S
D
F
V
V
L
A
V
P
L
T
R
E
T
Y
H
L
I
N
E
E
R
L
K
L
M
K
K
T
A
I
L
I
N
I
A
R
G
K
V
V
D
T
N
A
L
V
K
A
L
K
E
G
W
I
A
G
A
G
L
D
V
F
E
E
E
-------
P
Y
Y
N
E
E
-
L
F
K
L
D
N
V
V
L
T
P
H
I
G
S
A
S
F
G
A
R
E
G
M
A
E
L
V
A
K
N
L
I
A
F
K
R
G
E
I
P
P
T
L
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
79.17
47%
6
- C1 -
2DBZ
3
GYAR_PYRHO
A:
[1-321]
-
M
K
P
K
V
F
I
T
R
E
I
P
-
E
V
-
G
I
K
M
L
E
D
--
E
-
F
E
V
E
V
W
G
D
E
K
-
E
-
I
P
R
E
I
L
L
K
K
V
K
E
V
D
A
L
V
T
M
L
S
E
--
R
I
D
K
E
V
F
E
N
A
-
P
K
L
R
I
V
A
N
Y
A
V
G
Y
D
N
I
D
I
E
E
A
T
K
R
G
I
Y
V
T
N
T
P
D
V
L
T
D
A
T
A
D
L
A
F
A
L
L
L
A
T
A
R
H
V
V
K
G
D
R
F
V
R
S
G
E
W
K
K
R
G
V
A
W
H
P
-------
K
---
W
F
L
G
Y
D
V
Y
G
K
T
I
G
I
I
G
L
G
R
I
G
Q
A
I
A
K
R
A
K
--
G
F
N
M
R
I
L
Y
Y
S
R
T
R
-
K
E
E
V
-
E
R
E
L
N
A
E
F
K
P
L
E
D
L
L
R
E
S
D
F
V
V
L
A
V
P
L
T
R
E
T
Y
H
L
I
N
E
E
R
L
K
L
M
K
K
T
A
I
L
I
N
I
A
R
G
K
V
V
D
T
N
A
L
V
K
A
L
K
E
G
W
I
A
G
A
G
L
D
V
F
E
E
E
-------
P
Y
Y
N
E
E
-
L
F
K
L
D
N
V
V
L
T
P
H
I
G
S
A
S
F
G
A
R
E
G
M
A
E
L
V
A
K
N
L
I
A
F
K
R
G
E
I
P
P
T
L
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
78.88
47%
7
- C1 -
2DBR
3
GYAR_PYRHO
B:
[1-321]
-
M
K
P
K
V
F
I
T
R
E
I
P
-
E
V
-
G
I
K
M
L
E
D
--
E
-
F
E
V
E
V
W
G
D
E
K
-
E
-
I
P
R
E
I
L
L
K
K
V
K
E
V
D
A
L
V
T
M
L
S
E
--
R
I
D
K
E
V
F
E
N
A
-
P
K
L
R
I
V
A
N
Y
A
V
G
Y
D
N
I
D
I
E
E
A
T
K
R
G
I
Y
V
T
N
T
P
D
V
L
T
D
A
T
A
D
L
A
F
A
L
L
L
A
T
A
R
H
V
V
K
G
D
R
F
V
R
S
G
E
W
KKR
G
V
A
W
H
P
-------
K
---
W
F
L
G
Y
D
V
Y
G
K
T
I
G
I
I
G
L
G
R
I
G
Q
A
I
A
K
R
A
K
--
G
F
N
M
R
I
L
Y
Y
S
R
T
R
-
K
E
E
V
-
E
R
E
L
N
A
E
F
K
P
L
E
D
L
L
R
E
S
D
F
V
V
L
A
V
P
L
T
R
E
T
Y
H
L
I
N
E
E
R
L
K
L
M
K
K
T
A
I
L
I
N
I
A
R
G
K
V
V
D
T
N
A
L
V
K
A
L
K
E
G
W
I
A
G
A
G
L
D
V
F
E
E
E
-------
P
Y
Y
N
E
E
-
L
F
K
L
D
N
V
V
L
T
P
H
I
G
S
A
S
F
G
A
R
E
G
M
A
E
L
V
A
K
N
L
I
A
F
K
R
G
E
I
P
P
T
L
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
78.83
47%
10
- C1 -
2DBR
4
GYAR_PYRHO
C:
[1-321]
-
M
K
P
K
V
F
I
T
R
E
I
P
-
E
V
-
G
I
K
M
L
E
D
--
E
-
F
E
V
E
V
W
G
D
E
K
-
E
-
I
P
R
E
I
L
L
K
K
V
K
E
V
D
A
L
V
T
M
L
S
E
--
R
I
D
K
E
V
F
E
N
A
-
P
K
L
R
I
V
A
N
Y
A
V
G
Y
D
N
I
D
I
E
E
A
T
K
R
G
I
Y
V
T
N
T
P
D
V
L
T
D
A
T
A
D
L
A
F
A
L
L
L
A
T
A
R
H
V
V
K
G
D
R
F
V
R
S
G
E
W
KKR
G
V
A
W
H
P
-------
K
---
W
F
L
G
Y
D
V
Y
G
K
T
I
G
I
I
G
L
G
R
I
G
Q
A
I
A
K
R
A
K
--
G
F
N
M
R
I
L
Y
Y
S
R
T
R
-
K
E
E
V
-
E
R
E
L
N
A
E
F
K
P
L
E
D
L
L
R
E
S
D
F
V
V
L
A
V
P
L
T
R
E
T
Y
H
L
I
N
E
E
R
L
K
L
M
K
K
T
A
I
L
I
N
I
A
R
G
K
V
V
D
T
N
A
L
V
K
A
L
K
E
G
W
I
A
G
A
G
L
D
V
F
E
E
E
-------
P
Y
Y
N
E
E
-
L
F
K
L
D
N
V
V
L
T
P
H
I
G
S
A
S
F
G
A
R
E
G
M
A
E
L
V
A
K
N
L
I
A
F
K
R
G
E
I
P
P
T
L
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
78.76
41%
-114
- C1 -
1WWK
1
?
A:
[26-307]
-------------------------------
E
V
I
-
Y
E
E
-
Y
-
P
D
E
D
R
L
V
E
L
V
K
D
V
E
A
I
I
V
R
--
S
K
P
K
V
T
R
R
V
I
E
S
A
-
P
K
L
K
V
I
A
R
A
G
V
G
L
D
N
I
D
V
E
A
A
K
E
K
G
I
E
V
V
N
A
P
A
A
S
S
R
S
V
A
E
L
A
V
G
L
M
F
S
V
A
R
K
I
A
F
A
D
R
K
M
R
E
G
V
W
---
A
--
K
K
E
-------
A
---
M
--
G
I
E
L
E
G
K
T
I
G
I
I
G
F
G
R
I
G
Y
Q
V
A
K
I
A
N
--
A
L
G
M
N
I
L
L
Y
D
P
Y
P
-
N
E
E
R
-
A
K
E
V
N
G
K
F
V
D
L
E
T
L
L
K
E
S
D
V
V
T
I
H
V
P
L
V
E
S
T
Y
H
L
I
N
E
E
R
L
K
L
M
K
K
T
A
I
L
I
N
T
S
R
G
P
V
V
D
T
N
A
L
V
K
A
L
K
E
G
W
I
A
G
A
G
L
D
V
F
E
E
E
-------
P
L
P
K
D
H
P
L
T
K
F
D
N
V
V
L
T
P
H
I
G
A
S
T
V
E
A
Q
E
R
A
G
V
E
V
A
E
K
V
V
K
I
L
K
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
124
HHSearch
78.70
48%
5
* C1 *
5AOV
24
?
A:
[2-324]
--
K
P
K
V
F
I
T
R
A
I
P
-
E
N
-
G
I
N
M
L
E
E
--
E
-
F
E
V
E
V
W
-
E
E
E
-
R
E
I
P
R
E
K
L
L
E
K
V
K
D
V
D
A
L
V
T
--
M
L
S
E
R
I
D
Q
E
V
F
E
N
A
-
P
R
L
R
I
V
A
N
Y
A
V
G
Y
D
N
I
D
V
E
E
A
T
R
R
G
I
Y
V
T
N
T
P
D
V
L
T
N
A
T
A
D
H
A
F
A
L
L
L
A
T
A
R
H
V
V
K
G
D
K
F
V
R
S
G
E
W
---
K
---
R
K
GIAWHPK
W
---
F
L
-
G
Y
E
L
Y
G
K
T
I
G
I
V
G
F
G
R
I
G
Q
A
I
A
R
R
A
K
--
G
F
N
M
R
I
L
Y
Y
S
R
T
R
-
K
S
Q
A
-
E
K
E
L
G
A
E
Y
R
P
L
E
E
V
L
K
E
S
D
F
V
I
L
A
V
P
L
T
K
E
T
M
Y
M
I
N
E
E
R
L
K
L
M
K
P
T
A
I
L
V
N
I
A
R
G
K
V
V
D
T
K
A
L
I
K
A
L
K
E
G
W
I
A
G
A
G
L
D
V
F
E
E
E
-------
P
Y
Y
-
N
E
E
L
F
S
L
D
N
V
V
L
T
P
H
I
G
S
A
T
F
E
A
R
E
A
M
A
E
L
V
A
R
N
L
I
A
F
K
R
G
E
I
P
P
T
L
V
N
K
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
77.87
46%
12
- C1 -
5AOV
24
?
A:
[1-321]
-
M
K
P
K
V
F
I
T
R
A
I
P
-
E
N
G
I
N
M
L
E
E
E
--
F
-
E
V
E
V
W
E
-
E
E
R
-
E
-
I
P
R
E
K
L
L
E
K
V
K
D
V
D
A
L
V
T
M
L
S
E
--
R
I
D
Q
E
V
F
E
N
A
-
P
R
L
R
I
V
A
N
Y
A
V
G
Y
D
N
I
D
V
E
E
A
T
R
R
G
I
Y
V
T
N
T
P
D
V
L
T
N
A
T
A
D
H
A
F
A
L
L
L
A
T
A
R
H
V
V
K
G
D
K
F
V
R
S
G
E
W
K
R
K
G
I
A
W
H
P
-------
K
---
W
F
L
G
Y
E
L
Y
G
K
T
I
G
I
V
G
F
G
R
I
G
Q
A
I
A
R
R
A
K
--
G
F
N
M
R
I
L
Y
Y
S
R
T
R
-
K
S
Q
A
-
E
K
E
L
G
A
E
Y
R
P
L
E
E
V
L
K
E
S
D
F
V
I
L
A
V
P
L
T
K
E
T
M
Y
M
I
N
E
E
R
L
K
L
M
K
P
T
A
I
L
V
N
I
A
R
G
K
V
V
D
T
K
A
L
I
K
A
L
K
E
G
W
I
A
G
A
G
L
D
V
F
E
E
E
-------
P
Y
Y
N
E
E
-
L
F
S
L
D
N
V
V
L
T
P
H
I
G
S
A
T
F
E
A
R
E
A
M
A
E
L
V
A
R
N
L
I
A
F
K
R
G
E
I
P
P
T
L
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
64
PsiBlast_CBE
77.85
31%
-111
- C1 -
2G76
3
SERA_HUMAN
A:
[49-327]
-------------------------------
Q
V
V
-
E
K
Q
-
N
-
L
S
K
E
E
L
I
A
E
L
Q
D
C
E
G
L
I
V
R
--
S
A
T
K
V
T
A
D
V
I
N
A
A
-
E
K
L
Q
V
V
G
R
A
G
T
G
V
D
N
V
D
L
E
A
A
T
R
K
G
I
L
V
M
N
T
P
N
G
N
S
L
S
A
A
E
L
T
C
G
M
I
M
C
L
A
R
Q
I
P
Q
A
T
A
S
M
K
D
G
K
W
------
E
R
K
-------
K
---
F
M
-
G
T
E
L
N
G
K
T
L
G
I
L
G
L
G
R
I
G
R
E
V
A
T
R
M
Q
--
S
F
G
M
K
T
I
G
Y
D
P
I
I
-
S
P
E
V
-
S
A
S
F
G
V
Q
Q
L
P
L
E
E
I
W
P
L
C
D
F
I
T
V
H
T
P
L
L
P
S
T
T
G
L
L
N
D
N
T
F
A
Q
C
K
K
G
V
R
V
V
N
C
A
R
G
G
I
V
D
E
G
A
L
L
R
A
L
Q
S
G
Q
C
A
G
A
A
L
D
V
F
T
E
E
-------
P
-
P
R
D
R
A
L
V
D
H
E
N
V
I
S
C
P
H
L
G
A
S
T
K
E
A
Q
S
R
C
G
E
E
I
A
V
Q
F
V
D
M
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
77.77
47%
6
- C1 -
2DBZ
3
GYAR_PYRHO
B:
[1-321]
-
M
K
P
K
V
F
I
T
R
E
I
P
-
E
V
-
G
I
K
M
L
E
D
--
E
-
F
E
V
E
V
W
G
D
E
K
-
E
-
I
P
R
E
I
L
L
K
K
V
K
E
V
D
A
L
V
T
M
L
S
E
--
R
I
D
K
E
V
F
E
N
A
-
P
K
L
R
I
V
A
N
Y
A
V
G
Y
D
N
I
D
I
E
E
A
T
K
R
G
I
Y
V
T
N
T
P
D
V
L
T
D
A
T
A
D
L
A
F
A
L
L
L
A
T
A
R
H
V
V
K
G
D
R
F
V
R
S
G
E
W
KKR
G
V
A
W
H
P
-------
K
---
W
F
L
G
Y
D
V
Y
G
K
T
I
G
I
I
G
L
G
R
I
G
Q
A
I
A
K
R
A
K
--
G
F
N
M
R
I
L
Y
Y
S
R
T
R
-
K
E
E
V
-
E
R
E
L
N
A
E
F
K
P
L
E
D
L
L
R
E
S
D
F
V
V
L
A
V
P
L
T
R
E
T
Y
H
L
I
N
E
E
R
L
K
L
M
K
K
T
A
I
L
I
N
I
A
R
G
K
V
V
D
T
N
A
L
V
K
A
L
K
E
G
W
I
A
G
A
G
L
D
V
F
E
E
E
-------
P
Y
Y
N
E
E
-
L
F
K
L
D
N
V
V
L
T
P
H
I
G
S
A
S
F
G
A
R
E
G
M
A
E
L
V
A
K
N
L
I
A
F
K
R
G
E
I
P
P
T
L
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
PsiBlast_CBE
77.18
41%
-115
- C1 -
1WWK
1
?
B:
[26-305]
-------------------------------
E
V
I
-
Y
E
E
-
Y
-
P
D
E
D
R
L
V
E
L
V
K
D
V
E
A
I
I
V
R
--
S
K
P
K
V
T
R
R
V
I
E
S
A
-
P
K
L
K
V
I
A
R
A
G
V
G
L
D
N
I
D
V
E
A
A
K
E
K
G
I
E
V
V
N
A
P
A
A
S
S
R
S
V
A
E
L
A
V
G
L
M
F
S
V
A
R
K
I
A
F
A
D
R
K
M
R
E
G
V
W
---
A
--
K
K
E
-------
A
---
M
--
G
I
E
L
E
G
K
T
I
G
I
I
G
F
G
R
I
G
Y
Q
V
A
K
I
A
N
--
A
L
G
M
N
I
L
L
Y
D
P
Y
P
-
N
E
E
R
-
A
K
E
V
N
G
K
F
V
D
L
E
T
L
L
K
E
S
D
V
V
T
I
H
V
P
L
V
E
S
T
Y
H
L
I
N
E
E
R
L
K
L
M
K
K
T
A
I
L
I
N
T
S
R
G
P
V
V
D
T
N
A
L
V
K
A
L
K
E
G
W
I
A
G
A
G
L
D
V
F
E
E
E
-------
P
L
P
K
D
H
P
L
T
K
F
D
N
V
V
L
T
P
H
I
G
A
S
T
V
E
A
Q
E
R
A
G
V
E
V
A
E
K
V
V
K
I
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
76.53
47%
14
- C1 -
5AOW
10
?
A:
[1-321]
-
M
K
P
K
V
L
I
T
R
A
I
P
-
E
N
-
G
I
E
L
L
R
E
--
H
F
E
V
E
V
W
E
-
H
E
H
-
E
-
I
P
R
E
V
L
L
E
K
V
K
D
V
D
A
L
V
T
M
L
S
E
--
K
I
D
R
E
V
F
D
A
A
-
P
R
L
R
I
V
A
N
Y
A
V
G
Y
D
N
I
D
I
E
E
A
T
K
R
G
I
Y
V
T
N
T
P
D
V
L
T
D
A
T
A
D
L
A
W
A
L
L
L
A
A
A
R
H
V
V
K
G
D
K
F
V
R
S
G
E
W
K
R
R
G
I
A
W
H
P
-------
K
---
M
F
L
G
Y
D
V
Y
G
K
T
I
G
I
V
G
F
G
R
I
G
Q
A
I
A
K
R
A
K
--
G
F
G
M
R
I
L
Y
T
A
R
S
R
-
K
P
E
A
-
E
K
E
L
G
A
E
F
K
P
L
E
E
L
L
R
E
S
D
F
V
V
L
A
V
P
L
T
K
E
T
Y
H
M
I
N
E
E
R
L
R
L
M
K
P
T
A
V
L
V
N
V
A
R
G
K
V
V
D
T
K
A
L
I
R
A
L
K
E
G
W
I
A
A
A
G
L
D
V
F
E
E
E
-------
P
-
Y
Y
D
E
E
L
F
A
L
D
N
V
V
L
T
P
H
I
G
S
A
T
F
G
A
R
E
G
M
A
E
L
V
A
K
N
L
I
A
F
K
N
G
E
V
P
P
T
L
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
76.34
38%
-15
- C1 -
2WWR
1
GRHPR_HUMAN
A:
[11-322]
-----
V
F
V
T
R
R
I
P
-
A
E
-
G
R
V
A
L
A
R
AA
D
-
C
E
V
E
Q
W
-
D
S
D
E
P
-
I
P
A
K
E
L
E
R
G
V
A
G
A
H
G
L
L
C
L
L
S
D
--
H
V
D
K
R
I
L
D
A
A
G
A
N
L
K
V
I
S
T
M
S
V
G
I
D
H
L
A
L
D
E
I
K
K
R
G
I
R
V
G
Y
T
P
D
V
L
T
D
T
T
A
E
L
A
V
S
L
L
L
T
T
C
R
R
L
P
E
A
I
E
E
V
K
N
G
G
W
---
T
S
W
K
P
L
-------
W
---
L
C
-
G
Y
G
L
T
Q
S
T
V
G
I
I
G
L
G
R
I
G
Q
A
I
A
R
R
L
K
P
F
G
V
Q
-
R
F
L
Y
T
G
R
Q
P
-
R
P
E
E
-
A
A
E
F
Q
A
E
F
V
S
T
P
E
L
A
A
Q
S
D
F
I
V
V
A
C
-------
G
L
C
N
K
D
F
F
Q
K
M
K
E
T
A
V
F
I
N
I
S
R
G
D
V
V
N
Q
D
D
L
Y
Q
A
L
A
S
G
K
I
A
A
A
G
L
D
V
T
S
P
E
-------
P
L
P
T
N
H
P
L
L
T
L
K
N
C
V
I
L
P
H
I
G
S
A
T
H
R
T
R
N
T
M
S
L
L
A
A
N
N
L
L
A
G
L
R
G
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
63
PsiBlast_CBE
76.17
31%
-112
- C1 -
2G76
3
SERA_HUMAN
B:
[49-327]
-------------------------------
Q
V
V
-
E
K
Q
-
N
-
L
S
K
E
E
L
I
A
E
L
Q
D
C
E
G
L
I
V
R
--
S
A
T
K
V
T
A
D
V
I
N
A
A
-
E
K
L
Q
V
V
G
R
A
G
T
G
V
D
N
V
D
L
E
A
A
T
R
K
G
I
L
V
M
N
T
P
N
G
N
S
L
S
A
A
E
L
T
C
G
M
I
M
C
L
A
R
Q
I
P
Q
A
T
A
S
M
K
D
G
K
W
------
E
R
K
-------
K
---
F
M
-
G
T
E
L
N
G
K
T
L
G
I
L
G
L
G
R
I
G
R
E
V
A
T
R
M
Q
--
S
F
G
M
K
T
I
G
Y
D
P
I
I
-
S
P
E
V
-
S
A
S
F
G
V
Q
Q
L
P
L
E
E
I
W
P
L
C
D
F
I
T
V
H
T
P
L
L
P
S
T
T
G
L
L
N
D
N
T
F
A
Q
C
K
K
G
V
R
V
V
N
C
A
R
G
G
I
V
D
E
G
A
L
L
R
A
L
Q
S
G
Q
C
A
G
A
A
L
D
V
F
T
E
E
-------
P
-
P
R
D
R
A
L
V
D
H
E
N
V
I
S
C
P
H
L
G
A
S
T
K
E
A
Q
S
R
C
G
E
E
I
A
V
Q
F
V
D
M
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
PsiBlast_CBE
75.78
32%
-25
- C1 -
4E5P
1
PTXD_PSEST
F:
[3-323]
---
P
K
L
V
I
T
H
R
V
H
-
E
E
-
I
L
Q
L
L
A
P
--
H
-
C
E
L
I
T
N
-
Q
T
D
S
T
-
L
T
R
E
E
I
L
R
R
C
R
D
A
Q
A
M
M
A
F
M
P
D
--
R
V
D
A
D
F
L
Q
A
C
-
P
E
L
R
V
I
G
C
A
L
K
G
F
D
N
F
D
V
D
A
C
T
A
R
G
V
W
L
T
F
V
P
D
L
L
T
V
P
T
A
E
L
A
I
G
L
A
V
G
L
G
R
H
L
R
A
A
D
A
F
V
R
S
G
Q
F
---
R
G
W
Q
P
R
-----------
F
Y
-
G
T
G
L
D
N
A
T
V
G
F
L
G
M
G
A
I
G
L
A
M
A
D
R
L
Q
--
G
W
G
A
T
L
Q
Y
H
A
R
K
A
L
D
T
Q
T
-
E
Q
R
L
G
L
R
Q
V
A
C
S
E
L
F
A
S
S
D
F
I
L
L
A
L
P
L
N
A
D
T
L
H
L
V
N
A
E
L
L
A
L
V
R
P
G
A
L
L
V
N
P
C
R
G
S
V
V
D
E
A
A
V
L
A
A
L
E
R
G
Q
L
G
G
Y
A
A
D
V
F
E
M
E
DWARADR
P
Q
Q
I
D
P
A
L
L
A
H
P
N
T
L
F
T
P
H
I
G
S
A
V
R
A
V
R
L
E
I
E
R
C
A
A
Q
N
I
L
Q
A
L
A
G
E
R
P
I
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
75.34
47%
16
- C1 -
5AOW
7
?
B:
[2-321]
--
K
P
K
V
L
I
T
R
A
I
P
-
E
N
-
G
I
E
L
L
R
E
--
H
F
E
V
E
V
W
E
-
H
E
H
-
E
-
I
P
R
E
V
L
L
E
K
V
K
D
V
D
A
L
V
T
M
L
S
E
--
K
I
D
R
E
V
F
D
A
A
-
P
R
L
R
I
V
A
N
Y
A
V
G
Y
D
N
I
D
I
E
E
A
T
K
R
G
I
Y
V
T
N
T
P
D
V
L
T
D
A
T
A
D
L
A
W
A
L
L
L
A
A
A
R
H
V
V
K
G
D
K
F
V
R
S
G
E
W
K
R
R
G
I
A
W
H
P
-------
K
---
M
F
L
G
Y
D
V
Y
G
K
T
I
G
I
V
G
F
G
R
I
G
Q
A
I
A
K
R
A
K
--
G
F
G
M
R
I
L
Y
T
A
R
S
R
-
K
P
E
A
-
E
K
E
L
G
A
E
F
K
P
L
E
E
L
L
R
E
S
D
F
V
V
L
A
V
P
L
T
K
E
T
Y
H
M
I
N
E
E
R
L
R
L
M
K
P
T
A
V
L
V
N
V
A
R
G
K
V
V
D
T
K
A
L
I
R
A
L
K
E
G
W
I
A
A
A
G
L
D
V
F
E
E
E
-------
P
-
Y
Y
D
E
E
L
F
A
L
D
N
V
V
L
T
P
H
I
G
S
A
T
F
G
A
R
E
G
M
A
E
L
V
A
K
N
L
I
A
F
K
N
G
E
V
P
P
T
L
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
PsiBlast_CBE
73.38
38%
-11
- C1 -
2GCG
3
GRHPR_HUMAN
B:
[11-322]
-----
V
F
V
T
R
R
I
P
-
A
E
-
G
R
V
A
L
A
R
AA
D
-
C
E
V
E
Q
W
-
D
S
D
E
P
-
I
P
A
K
E
L
E
R
G
V
A
G
A
H
G
L
L
C
L
L
S
D
--
H
V
D
K
R
I
L
D
A
A
G
A
N
L
K
V
I
S
T
M
S
V
G
I
D
H
L
A
L
D
E
I
K
K
R
G
I
R
V
G
Y
T
P
D
V
L
T
D
T
T
A
E
L
A
V
S
L
L
L
T
T
C
R
R
L
P
E
A
I
E
E
V
K
N
G
G
W
---
T
S
W
K
P
L
-------
W
---
L
C
-
G
Y
G
L
T
Q
S
T
V
G
I
I
G
L
G
R
I
G
Q
A
I
A
R
R
L
K
P
F
G
V
Q
-
R
F
L
Y
T
G
R
Q
P
-
R
P
E
E
-
A
A
E
F
Q
A
E
F
V
S
T
P
E
L
A
A
Q
S
D
F
I
V
V
A
C
S
L
T
P
A
T
E
G
L
C
N
K
D
F
F
Q
K
M
K
E
T
A
V
F
I
N
I
S
R
G
D
V
V
N
Q
D
D
L
Y
Q
A
L
A
S
G
K
I
A
A
A
G
L
D
V
T
S
P
E
-------
P
L
P
T
N
H
P
L
L
T
L
K
N
C
V
I
L
P
H
I
G
S
A
T
H
R
T
R
N
T
M
S
L
L
A
A
N
N
L
L
A
G
L
R
G
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
72.98
38%
-10
- C1 -
2GCG
3
GRHPR_HUMAN
A:
[11-322]
-----
V
F
V
T
R
R
I
P
-
A
E
-
G
R
V
A
L
A
R
AA
D
-
C
E
V
E
Q
W
-
D
S
D
E
P
-
I
P
A
K
E
L
E
R
G
V
A
G
A
H
G
L
L
C
L
L
S
D
--
H
V
D
K
R
I
L
D
A
A
G
A
N
L
K
V
I
S
T
M
S
V
G
I
D
H
L
A
L
D
E
I
K
K
R
G
I
R
V
G
Y
T
P
D
V
L
T
D
T
T
A
E
L
A
V
S
L
L
L
T
T
C
R
R
L
P
E
A
I
E
E
V
K
N
G
G
W
---
T
S
W
K
P
L
-------
W
---
L
C
-
G
Y
G
L
T
Q
S
T
V
G
I
I
G
L
G
R
I
G
Q
A
I
A
R
R
L
K
P
F
G
V
Q
-
R
F
L
Y
T
G
R
Q
P
-
R
P
E
E
-
A
A
E
F
Q
A
E
F
V
S
T
P
E
L
A
A
Q
S
D
F
I
V
V
A
C
S
L
T
P
A
T
E
G
L
C
N
K
D
F
F
Q
K
M
K
E
T
A
V
F
I
N
I
S
R
G
D
V
V
N
Q
D
D
L
Y
Q
A
L
A
S
G
K
I
A
A
A
G
L
D
V
T
S
P
E
-------
P
L
P
T
N
H
P
L
L
T
L
K
N
C
V
I
L
P
H
I
G
S
A
T
H
R
T
R
N
T
M
S
L
L
A
A
N
N
L
L
A
G
L
R
G
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
PsiBlast_CBE
72.73
38%
-7
- C1 -
2GCG
5
GRHPR_HUMAN
C:
[11-322]
-----
V
F
V
T
R
R
I
P
-
A
E
-
G
R
V
A
L
A
R
AA
D
-
C
E
V
E
Q
W
-
D
S
D
E
P
-
I
P
A
K
E
L
E
R
G
V
A
G
A
H
G
L
L
C
L
L
S
D
--
H
V
D
K
R
I
L
D
A
A
G
A
N
L
K
V
I
S
T
M
S
V
G
I
D
H
L
A
L
D
E
I
K
K
R
G
I
R
V
G
Y
T
P
D
V
L
T
D
T
T
A
E
L
A
V
S
L
L
L
T
T
C
R
R
L
P
E
A
I
E
E
V
K
N
G
G
W
---
T
S
W
K
P
L
-------
W
---
L
C
-
G
Y
G
L
T
Q
S
T
V
G
I
I
G
L
G
R
I
G
Q
A
I
A
R
R
L
K
P
F
G
V
Q
-
R
F
L
Y
T
G
R
Q
P
-
R
P
E
E
-
A
A
E
F
Q
A
E
F
V
S
T
P
E
L
A
A
Q
S
D
F
I
V
V
A
C
S
L
T
P
A
T
E
G
L
C
N
K
D
F
F
Q
K
M
K
E
T
A
V
F
I
N
I
S
R
G
D
V
V
N
Q
D
D
L
Y
Q
A
L
A
S
G
K
I
A
A
A
G
L
D
V
T
S
P
E
-------
P
L
P
T
N
H
P
L
L
T
L
K
N
C
V
I
L
P
H
I
G
S
A
T
H
R
T
R
N
T
M
S
L
L
A
A
N
N
L
L
A
G
L
R
G
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
132
HHSearch
72.53
39%
-15
- C1 -
1WWK
1
?
A:
[4-307]
---
M
K
V
L
V
A
A
P
L
H
-
E
K
-
A
I
Q
V
L
K
D
A
-
G
-
L
E
V
I
Y
E
-
E
Y
----
P
D
E
D
R
L
V
E
L
V
K
D
V
E
A
I
I
V
--
R
S
K
P
K
V
T
R
R
V
I
E
S
A
-
P
K
L
K
V
I
A
R
A
G
V
G
L
D
N
I
D
V
E
A
A
K
E
K
G
I
E
V
V
N
A
P
A
A
S
S
R
S
V
A
E
L
A
V
G
L
M
F
S
V
A
R
K
I
A
F
A
D
R
K
M
R
E
G
V
W
---
A
---
K
K
-------
E
---
A
M
-
G
I
E
L
E
G
K
T
I
G
I
I
G
F
G
R
I
G
Y
Q
V
A
K
I
A
N
--
A
L
G
M
N
I
L
L
Y
D
P
Y
P
-
N
E
E
R
-
A
K
E
V
N
G
K
F
V
D
L
E
T
L
L
K
E
S
D
V
V
T
I
H
V
P
L
V
E
S
T
Y
H
L
I
N
E
E
R
L
K
L
M
K
K
T
A
I
L
I
N
T
S
R
G
P
V
V
D
T
N
A
L
V
K
A
L
K
E
G
W
I
A
G
A
G
L
D
V
F
E
E
E
-------
P
L
P
K
D
H
P
L
T
K
F
D
N
V
V
L
T
P
H
I
G
A
S
T
V
E
A
Q
E
R
A
G
V
E
V
A
E
K
V
V
K
I
L
K
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
130
HHSearch
70.71
37%
-2
- C1 -
2GCG
3
GRHPR_HUMAN
A:
[7-329]
-
R
L
M
K
V
F
V
T
R
R
I
P
-
A
E
-
G
R
V
A
L
A
R
AA
D
-
C
E
V
E
Q
W
-
D
S
D
E
P
-
I
P
A
K
E
L
E
R
G
V
A
G
A
H
G
L
L
C
--
L
L
S
D
H
V
D
K
R
I
L
D
A
A
G
A
N
L
K
V
I
S
T
M
S
V
G
I
D
H
L
A
L
D
E
I
K
K
R
G
I
R
V
G
Y
T
P
D
V
L
T
D
T
T
A
E
L
A
V
S
L
L
L
T
T
C
R
R
L
P
E
A
I
E
E
V
K
N
G
G
W
---
T
---
S
W
-------
K
PLW
L
C
-
G
Y
G
L
T
Q
S
T
V
G
I
I
G
L
G
R
I
G
Q
A
I
A
R
R
L
K
--
P
F
G
V
Q
R
F
L
Y
T
G
R
Q
-
P
R
P
E
E
A
A
E
F
Q
A
E
F
V
S
T
P
E
L
A
A
Q
S
D
F
I
V
V
A
C
S
L
T
P
A
T
E
G
L
C
N
K
D
F
F
Q
K
M
K
E
T
A
V
F
I
N
I
S
R
G
D
V
V
N
Q
D
D
L
Y
Q
A
L
A
S
G
K
I
A
A
A
G
L
D
V
T
S
P
E
-------
P
L
P
T
N
H
P
L
L
T
L
K
N
C
V
I
L
P
H
I
G
S
A
T
H
R
T
R
N
T
M
S
L
L
A
A
N
N
L
L
A
G
L
R
G
E
P
M
P
S
E
L
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
PsiBlast_CBE
69.94
38%
-22
- C1 -
2CUK
1
?
C:
[3-308]
-----
V
L
V
T
R
T
L
P
G
K
A
-
L
D
R
L
R
E
R
--
G
-
L
E
V
E
V
H
-
R
G
L
-
F
-
L
P
K
A
E
L
L
K
R
V
E
G
A
V
G
L
I
P
--
T
V
E
D
R
I
D
A
E
V
M
D
R
A
-
K
G
L
K
V
I
A
C
Y
S
V
G
V
D
H
V
D
L
E
A
A
R
E
R
G
I
R
V
T
H
T
P
G
V
L
T
E
A
T
A
D
L
T
L
A
L
L
L
A
V
A
R
R
V
V
E
G
A
A
Y
A
R
D
G
L
W
---
K
A
W
H
P
E
-------
L
---
L
L
-
G
L
D
L
Q
G
L
T
L
G
L
V
G
M
G
R
I
G
Q
A
V
A
K
R
A
--
L
A
F
G
M
R
V
V
Y
H
A
R
------
T
-
P
K
P
L
P
Y
P
F
L
S
L
E
E
L
L
K
E
A
D
V
V
S
L
H
T
P
L
T
P
E
T
H
R
L
L
N
R
E
R
L
F
A
M
K
R
G
A
I
L
L
N
T
A
R
G
A
L
V
D
T
E
A
L
V
E
A
L
R
-
G
H
L
F
G
A
G
L
D
V
T
D
P
E
-------
P
L
P
P
G
H
P
L
Y
A
L
P
N
A
V
I
T
P
H
I
G
S
A
G
R
T
T
R
E
R
M
A
E
V
A
V
E
N
L
L
A
V
L
E
G
R
E
P
P
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------