@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu34700: (2016-07-28 )
MNVLQTTNLSKTYYSNKGTISYQALSAFDLSVSKGEFVGIMGPSGSGKTTLLNLLATIDKPTQGEMMINGIQPKTLKDQELALFRRRELGFVFQDFNLLDTLTIRENILLPLALDKVKLREMEARLDELADTLQIKHILDHRTYEVSGGQQQRAACARAIIHNPALILADEPTGNLDSKSAKQVMNTLAQLNEEKEATILLVTHDATAASFCKRIVFIKDGRFFSEIHRGTNRQVFYQSILDTLSVLGGDFHEFENYRP
Atome Classification :
(43 SA)
.........10........20........30........40........50........60........70........80..----......90........100......-.110.---.....--.----..120.......130..-...--.----.140...--.....150.......160.......170.......180.......190.......200...-..-..210........220.......230.......240.......250.......----------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MNVLQTTNLS
K
T
Y
YSNKG
T
I
S
Y
Q
A
L
S
A
F
DLSVSKG
E
F
V
G
I
MGPSGS
G
K
T
T
L
L
N
L
L
A
TIDKPTQG
E
M
M
I
NGIQPKTL
K
D
Q
E
L
A
L
----
F
R
R
R
EL
G
F
V
F
Q
DFNL
L
D
T
L
T
IREN
I
-
L
L
--P---LA
L
D
K
--
V
----
K
L
R
E
M
E
A
R
L
D
E
L
A
D
T
L
Q
-
I
K
H
--
I
----LDH-R
T
Y
--EVSGG
Q
Q
Q
R
A
A
C
A
R
A
I
IHN
P
A
L
I
L
ADEPTGNL
D
S
K
S
A
K
Q
V
M
N
T
L
A
Q
LNEEK
E
A
T
I
L
L
V
THD-
A
T
-
A
A
S
-
F
C
K
R
I
V
F
IKDG
R
F
F
S
E
I
HRGTN
R
Q
V
F
Y
Q
S
I
L
D
T
L
S
V
LGG
D
F
H
E
FENYRP----------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
75.94
34%
-126
* C1 *
3DHW
-
METN_ECOLI
C:
[1-229]
--
M
I
K
L
S
N
I
T
K
V
F
H
--
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
E
L
T
-----
K
A
R
R
Q
I
G
M
I
F
Q
H
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
--
P
---
L
E
L
D
N
--
T
----
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
-
L
G
D
--
K
----
H
D
S
-
Y
P
S
--
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
E
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
-
M
D
-
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
---
I
E
Q
D
T
V
S
E
V
F
---------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
75.37
32%
-111
- C1 -
1OXU
7
?
A:
[8-248]
-------
N
V
S
K
V
F
--
K
K
G
K
V
V
--
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
D
-
R
L
V
A
S
N
G
K
L
I
V
P
----
P
E
D
R
K
I
G
M
V
F
Q
T
W
A
L
Y
P
N
L
T
A
F
E
N
I
-
A
F
--
P
---
L
T
N
M
K
--
M
----
S
K
E
E
I
R
K
R
V
E
E
V
A
K
I
L
D
-
I
H
H
--
V
----
L
N
H
-
F
P
R
--
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
L
G
V
T
L
L
V
V
S
H
D
P
A
D
-
I
F
A
-
I
A
D
R
V
G
V
L
V
K
G
K
L
---
V
Q
V
G
K
P
E
D
L
Y
D
N
P
V
S
I
Q
V
A
S
L
I
G
E
I
N
E
L
E
--------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
75.21
43%
-25
- C1 -
1L2T
4
Y796_METJA
A:
[1-226]
--
M
I
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
--
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
N
D
L
D
D
D
E
L
T
K
----
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
-
E
L
--
P
---
L
I
F
K
Y
--
R
----
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
-
M
A
E
--
L
EERF
A
N
H
-
K
P
N
--
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
-
I
N
-
V
A
R
-
F
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
E
-------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
74.71
33%
-119
- C1 -
3TUI
1
METN_ECOLI
C:
[23-252]
-
H
M
I
K
L
S
N
I
T
K
V
F
H
--
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
E
L
T
-----
K
A
R
R
Q
I
G
M
I
F
Q
H
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
--
P
---
L
E
L
D
N
--
T
----
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
-
L
G
D
--
K
----
H
D
S
-
Y
P
S
--
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
-
M
D
-
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
---
I
E
Q
D
T
V
S
E
V
F
---------------------------------------------------------------------------------------------------------------------------
33
PsiBlast_CBE
74.43
32%
-116
- C1 -
1OXV
15
?
D:
[8-248]
-------
N
V
S
K
V
F
--
K
K
G
K
V
V
--
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
D
-
R
L
V
A
S
N
G
K
L
I
V
P
----
P
E
D
R
K
I
G
M
V
F
Q
T
W
A
L
Y
P
N
L
T
A
F
E
N
I
-
A
F
--
P
---
L
T
N
M
K
--
M
----
S
K
E
E
I
R
K
R
V
E
E
V
A
K
I
L
D
-
I
H
H
--
V
----
L
N
H
-
F
P
R
--
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
L
G
V
T
L
L
V
V
S
H
D
P
A
D
-
I
F
A
-
I
A
D
R
V
G
V
L
V
K
G
K
L
---
V
Q
V
G
K
P
E
D
L
Y
D
N
P
V
S
I
Q
V
A
S
L
I
G
E
I
N
E
L
E
--------------------------------------------------------------------------------------------------------
35
PsiBlast_CBE
74.04
32%
-113
- C1 -
1OXU
13
?
C:
[8-248]
-------
N
V
S
K
V
F
--
K
K
G
K
V
V
--
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
D
-
R
L
V
A
S
N
G
K
L
I
V
P
----
P
E
D
R
K
I
G
M
V
F
Q
T
W
A
L
Y
P
N
L
T
A
F
E
N
I
-
A
F
--
P
---
L
T
N
M
K
--
M
----
S
K
E
E
I
R
K
R
V
E
E
V
A
K
I
L
D
-
I
H
H
--
V
----
L
N
H
-
F
P
R
--
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
L
G
V
T
L
L
V
V
S
H
D
P
A
D
-
I
F
A
-
I
A
D
R
V
G
V
L
V
K
G
K
L
---
V
Q
V
G
K
P
E
D
L
Y
D
N
P
V
S
I
Q
V
A
S
L
I
G
E
I
N
E
L
E
--------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
73.80
43%
-24
- C1 -
1F3O
2
Y796_METJA
A:
[2-226]
---
I
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
--
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
N
D
L
D
D
D
E
L
T
K
----
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
-
E
L
--
P
---
L
I
F
K
Y
--
R
----
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
-
M
A
E
--
L
EERF
A
N
H
-
K
P
N
--
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
E
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
-
I
N
-
V
A
R
-
F
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
E
-------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
73.69
32%
-111
- C1 -
1OXV
7
?
A:
[8-248]
-------
N
V
S
K
V
F
--
K
K
G
K
V
V
--
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
D
-
R
L
V
A
S
N
G
K
L
I
V
P
----
P
E
D
R
K
I
G
M
V
F
Q
T
W
A
L
Y
P
N
L
T
A
F
E
N
I
-
A
F
--
P
---
L
T
N
M
K
--
M
----
S
K
E
E
I
R
K
R
V
E
E
V
A
K
I
L
D
-
I
H
H
--
V
----
L
N
H
-
F
P
R
--
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
L
G
V
T
L
L
V
V
S
H
D
P
A
D
-
I
F
A
-
I
A
D
R
V
G
V
L
V
K
G
K
L
---
V
Q
V
G
K
P
E
D
L
Y
D
N
P
V
S
I
Q
V
A
S
L
I
G
E
I
N
E
L
E
--------------------------------------------------------------------------------------------------------
36
PsiBlast_CBE
73.66
32%
-114
- C1 -
1OXU
7
?
B:
[8-248]
-------
N
V
S
K
V
F
--
K
K
G
K
V
V
--
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
D
-
R
L
V
A
S
N
G
K
L
I
V
P
----
P
E
D
R
K
I
G
M
V
F
Q
T
W
A
L
Y
P
N
L
T
A
F
E
N
I
-
A
F
--
P
---
L
T
N
M
K
--
M
----
S
K
E
E
I
R
K
R
V
E
E
V
A
K
I
L
D
-
I
H
H
--
V
----
L
N
H
-
F
P
R
--
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
L
G
V
T
L
L
V
V
S
H
D
P
A
D
-
I
F
A
-
I
A
D
R
V
G
V
L
V
K
G
K
L
---
V
Q
V
G
K
P
E
D
L
Y
D
N
P
V
S
I
Q
V
A
S
L
I
G
E
I
N
E
L
E
--------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
73.62
33%
-126
- C1 -
3TUZ
1
METN_ECOLI
C:
[23-252]
-
H
M
I
K
L
S
N
I
T
K
V
F
H
--
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
E
L
T
-----
K
A
R
R
Q
I
G
M
I
F
Q
H
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
--
P
---
L
E
L
D
N
--
T
----
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
-
L
G
D
--
K
----
H
D
S
-
Y
P
S
--
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
-
M
D
-
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
---
I
E
Q
D
T
V
S
E
V
F
---------------------------------------------------------------------------------------------------------------------------
28
PsiBlast_CBE
73.09
33%
-124
- C1 -
3TUI
1
METN_ECOLI
H:
[23-252]
-
H
M
I
K
L
S
N
I
T
K
V
F
H
--
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
E
L
T
-----
K
A
R
R
Q
I
G
M
I
F
Q
H
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
--
P
---
L
E
L
D
N
--
T
----
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
-
L
G
D
--
K
----
H
D
S
-
Y
P
S
--
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
-
M
D
-
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
---
I
E
Q
D
T
V
S
E
V
F
---------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
72.72
43%
-48
- C1 -
2PCJ
-
LOLD_AQUAE
A:
[16-223]
--------------------
G
Y
E
I
L
K
G
I
S
L
S
V
K
K
G
E
F
V
S
I
I
G
A
S
G
S
G
K
S
T
L
L
Y
I
L
G
L
L
D
A
P
T
E
G
K
V
F
L
E
G
K
E
V
D
Y
T
N
E
K
E
L
S
L
----
L
R
N
R
K
L
G
F
V
F
Q
F
H
Y
L
I
P
E
L
T
A
L
E
N
V
-
I
V
--
P
M
--
L
K
M
G
K
--
P
----
K
-
K
E
A
K
E
R
G
E
Y
L
L
S
E
L
G
-
L
G
D
--
K
----
L
S
R
-
K
P
Y
--
E
L
S
G
G
E
Q
Q
R
V
A
I
A
R
A
L
A
N
E
P
I
L
L
F
A
D
E
P
T
G
N
L
D
S
A
N
T
K
R
V
M
D
I
F
L
K
I
N
-
E
G
G
T
S
I
V
M
V
T
H
E
-
R
E
-
L
A
E
-
L
T
H
R
T
L
E
M
K
D
G
K
V
V
G
E
I
T
R
----------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
72.61
33%
-123
- C1 -
3TUZ
1
METN_ECOLI
G:
[24-252]
--
M
I
K
L
S
N
I
T
K
V
F
H
--
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
E
L
T
-----
K
A
R
R
Q
I
G
M
I
F
Q
H
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
--
P
---
L
E
L
D
N
--
T
----
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
-
L
G
D
--
K
----
H
D
S
-
Y
P
S
--
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
-
M
D
-
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
---
I
E
Q
D
T
V
S
E
V
F
---------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
72.24
43%
-25
- C1 -
3TIF
7
Y796_METJA
A:
[1-226]
--
M
V
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
--
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
N
D
L
D
D
D
E
L
T
K
----
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
-
E
L
--
P
---
L
I
F
K
Y
--
R
----
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
-
M
A
E
--
L
EERF
A
N
H
-
K
P
N
--
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
-
I
N
-
V
A
R
-
F
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
E
-------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
72.17
32%
-108
- C1 -
1OXT
-
?
A:
[8-248]
-------
N
V
S
K
V
F
--
K
K
G
K
V
V
--
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
D
-
R
L
V
A
S
N
G
K
L
I
V
P
----
P
E
D
R
K
I
G
M
V
F
Q
T
W
A
L
Y
P
N
L
T
A
F
E
N
I
-
A
F
--
P
---
L
T
N
M
K
--
M
----
S
K
E
E
I
R
K
R
V
E
E
V
A
K
I
L
D
-
I
H
H
--
V
----
L
N
H
-
F
P
R
--
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
L
G
V
T
L
L
V
V
S
H
D
P
A
D
-
I
F
A
-
I
A
D
R
V
G
V
L
V
K
G
K
L
---
V
Q
V
G
K
P
E
D
L
Y
D
N
P
V
S
I
Q
V
A
S
L
I
G
E
I
N
E
L
E
--------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
72.09
32%
-108
- C1 -
1OXS
19
?
C:
[8-248]
-------
N
V
S
K
V
F
--
K
K
G
K
V
V
--
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
D
-
R
L
V
A
S
N
G
K
L
I
V
P
----
P
E
D
R
K
I
G
M
V
F
Q
T
W
A
L
Y
P
N
L
T
A
F
E
N
I
-
A
F
--
P
---
L
T
N
M
K
--
M
----
S
K
E
E
I
R
K
R
V
E
E
V
A
K
I
L
D
-
I
H
H
--
V
----
L
N
H
-
F
P
R
--
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
L
G
V
T
L
L
V
V
S
H
D
P
A
D
-
I
F
A
-
I
A
D
R
V
G
V
L
V
K
G
K
L
---
V
Q
V
G
K
P
E
D
L
Y
D
N
P
V
S
I
Q
V
A
S
L
I
G
E
I
N
E
L
E
--------------------------------------------------------------------------------------------------------
112
Fugue
71.82
31%
-103
- C1 -
1OXS
23
?
C:
[1-352]
M
V
R
I
I
V
K
N
V
S
K
V
F
K
K
G
K
----
V
V
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
D
R
L
V
A
S
-
N
G
K
L
I
V
P
----
P
E
D
R
K
I
G
M
V
F
Q
T
W
A
L
Y
P
N
L
T
A
F
E
N
I
-
A
F
--
P
---
L
T
N
M
K
--
M
----
S
K
E
E
I
R
K
R
V
E
E
V
A
K
I
L
D
-
I
H
H
--
V
----
L
N
H
-
F
P
R
--
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
L
G
V
T
L
L
V
V
S
H
D
-
P
A
D
I
F
A
-
I
A
D
R
V
G
V
L
V
K
G
K
L
V
Q
V
---
G
K
P
E
D
L
Y
D
N
P
V
S
I
Q
V
A
S
L
I
G
E
I
N
E
L
E
G
K
V
T
NEGVVIGSLRFPVSVSSDRAIIGIRPEDVKLSKDVIKDDSWILVGKGKVKVIGYQGGLFRITITPLDSEEEIFTYSDHPIHSGEEVLVYVRKDKIKVFEK
5
PsiBlast_PDB
71.68
43%
-44
- C1 -
2PCL
12
LOLD_AQUAE
A:
[16-223]
--------------------
G
Y
E
I
L
K
G
I
S
L
S
V
K
K
G
E
F
V
S
I
I
G
A
S
G
S
G
K
S
T
L
L
Y
I
L
G
L
L
D
A
P
T
E
G
K
V
F
L
E
G
K
E
V
D
Y
T
N
E
K
E
L
S
L
----
L
R
N
R
K
L
G
F
V
F
Q
F
H
Y
L
I
P
E
L
T
A
L
E
N
V
-
I
V
--
P
M
--
L
K
M
G
K
--
P
----
K
-
K
E
A
K
E
R
G
E
Y
L
L
S
E
L
G
-
L
G
D
--
K
----
L
S
R
-
K
P
Y
--
E
L
S
G
G
E
Q
Q
R
V
A
I
A
R
A
L
A
N
E
P
I
L
L
F
A
D
E
P
T
G
N
L
D
S
A
N
T
K
R
V
M
D
I
F
L
K
I
N
-
E
G
G
T
S
I
V
M
V
T
H
E
-
R
E
-
L
A
E
-
L
T
H
R
T
L
E
M
K
D
G
K
V
V
G
E
I
T
R
----------------------------------------------------------------------------------------------------------------------------------
34
PsiBlast_CBE
71.49
32%
-111
- C1 -
1OXV
4
?
B:
[8-248]
-------
N
V
S
K
V
F
--
K
K
G
K
V
V
--
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
D
-
R
L
V
A
S
N
G
K
L
I
V
P
----
P
E
D
R
K
I
G
M
V
F
Q
T
W
A
L
Y
P
N
L
T
A
F
E
N
I
-
A
F
--
P
---
L
T
N
M
K
--
M
----
S
K
E
E
I
R
K
R
V
E
E
V
A
K
I
L
D
-
I
H
H
--
V
----
L
N
H
-
F
P
R
--
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
L
G
V
T
L
L
V
V
S
H
D
P
A
D
-
I
F
A
-
I
A
D
R
V
G
V
L
V
K
G
K
L
---
V
Q
V
G
K
P
E
D
L
Y
D
N
P
V
S
I
Q
V
A
S
L
I
G
E
I
N
E
L
E
--------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
71.49
43%
-28
- C1 -
1L2T
4
Y796_METJA
B:
[1-226]
--
M
I
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
--
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
N
D
L
D
D
D
E
L
T
K
----
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
-
E
L
--
P
---
L
I
F
K
Y
--
R
----
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
-
M
A
E
--
L
EERF
A
N
H
-
K
P
N
--
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
-
I
N
-
V
A
R
-
F
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
E
-------------------------------------------------------------------------------------------------------------------------------------
128
HHSearch
64.34
32%
-111
- C1 -
3FVQ
3
FBPC_NEIG1
A:
[3-230]
-
A
A
L
H
I
G
H
L
S
K
S
F
Q
N
------
T
P
V
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
G
K
T
I
F
S
K
N
T
N
-
L
-
P
----
V
R
E
R
R
L
G
Y
L
V
Q
E
G
V
L
F
P
H
L
T
V
Y
R
N
I
-
A
Y
--
G
---
L
G
N
G
K
--
G
----
R
T
A
Q
E
R
Q
R
I
E
A
M
L
E
L
T
G
-
I
S
E
--
L
----
A
G
R
-
Y
P
H
--
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
A
N
G
K
S
A
V
F
V
S
H
D
-
R
E
E
A
L
Q
-
Y
A
D
R
I
A
V
M
K
Q
G
R
I
L
Q
T
A
S
P
H
E
--------------------------------------------------------------------------------------------------------------------------------
40
PsiBlast_CBE
59.28
32%
-130
- C1 -
1VCI
1
?
A:
[24-228]
--------------------
N
F
T
A
V
N
K
L
N
L
T
I
K
D
G
E
F
L
V
L
L
G
P
S
G
C
G
K
T
T
T
L
R
M
I
A
G
L
E
E
P
T
E
G
R
I
Y
F
G
D
------
R
D
V
T
Y
L
P
----
P
K
D
R
N
I
S
M
V
F
Q
------
H
M
T
V
Y
E
N
I
-
A
F
--
P
---
L
--
K
K
--
F
----
P
K
D
E
I
D
K
R
V
R
W
A
A
E
L
L
Q
-
I
E
E
--
L
----
L
N
R
-
Y
P
A
--
Q
L
S
G
G
Q
R
Q
R
V
A
V
A
R
A
I
V
V
E
P
D
V
L
L
M
D
E
P
L
S
N
L
D
A
K
L
R
V
A
M
R
A
E
I
K
K
L
Q
Q
K
L
K
V
T
T
I
Y
V
T
H
D
-
Q
V
E
A
M
T
-
M
G
D
R
I
A
V
M
N
R
G
Q
L
L
---------------------------------------------------------------------------------------------------------------------------------------
86
PsiBlast_CBE
58.65
33%
-34
- C1 -
4U00
3
?
A:
[4-226]
--
I
I
R
I
R
N
L
H
K
W
F
G
P
------
L
H
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
L
---
S
V
K
D
D
R
A
L
R
----
E
I
R
R
E
V
G
M
V
F
Q
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
T
L
A
--
P
---
M
R
V
R
R
--
W
----
P
R
E
K
A
E
K
K
A
L
E
L
L
E
R
V
G
-
I
---------
L
D
Q
A
R
K
Y
PA
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
A
-
Q
G
G
M
T
M
V
V
V
T
H
E
M
G
F
-
A
R
E
-
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
E
E
---
G
R
P
E
E
I
F
---------------------------------------------------------------------------------------------------------------------------
72
PsiBlast_CBE
57.53
36%
-61
- C1 -
2OLK
1
?
D:
[36-240]
--------------------
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
A
-
K
D
T
N
L
N
K
----
V
R
E
-
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
--
P
---
M
K
V
R
K
--
W
----
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
-
L
K
D
--
K
----
A
H
A
-
Y
P
D
--
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
G
-
M
T
M
V
V
V
T
H
E
M
G
F
-
A
R
E
-
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
-------------------------------------------------------------------------------------------------------------------------------------
77
PsiBlast_CBE
57.39
36%
-61
- C1 -
2OLJ
4
?
A:
[36-240]
--------------------
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
A
-
K
D
T
N
L
N
K
----
V
R
E
-
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
--
P
---
M
K
V
R
K
--
W
----
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
-
L
K
D
--
K
----
A
H
A
-
Y
P
D
--
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
G
-
M
T
M
V
V
V
T
H
E
M
G
F
-
A
R
E
-
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
-------------------------------------------------------------------------------------------------------------------------------------
78
PsiBlast_CBE
56.06
36%
-59
- C1 -
3C41
3
?
K:
[15-219]
--------------------
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
A
-
K
D
T
N
L
N
K
----
V
R
E
-
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
--
P
---
M
K
V
R
K
--
W
----
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
-
L
K
D
--
K
----
A
H
A
-
Y
P
D
--
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
G
-
M
T
M
V
V
V
T
H
E
M
G
F
-
A
R
E
-
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
-------------------------------------------------------------------------------------------------------------------------------------
73
PsiBlast_CBE
55.78
36%
-62
- C1 -
2OLK
1
?
C:
[36-240]
--------------------
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
A
-
K
D
T
N
L
N
K
----
V
R
E
-
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
--
P
---
M
K
V
R
K
--
W
----
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
-
L
K
D
--
K
----
A
H
A
-
Y
P
D
--
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
G
-
M
T
M
V
V
V
T
H
E
M
G
F
-
A
R
E
-
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
-------------------------------------------------------------------------------------------------------------------------------------
67
PsiBlast_CBE
55.43
36%
-55
- C1 -
2Q0H
4
?
A:
[36-240]
--------------------
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
A
-
K
D
T
N
L
N
K
----
V
R
E
-
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
--
P
---
M
K
V
R
K
--
W
----
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
-
L
K
D
--
K
----
A
H
A
-
Y
P
D
--
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
G
-
M
T
M
V
V
V
T
H
E
M
G
F
-
A
R
E
-
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
-------------------------------------------------------------------------------------------------------------------------------------
65
PsiBlast_CBE
55.21
36%
-54
- C1 -
3C4J
3
?
A:
[36-240]
--------------------
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
A
-
K
D
T
N
L
N
K
----
V
R
E
-
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
--
P
---
M
K
V
R
K
--
W
----
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
-
L
K
D
--
K
----
A
H
A
-
Y
P
D
--
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
G
-
M
T
M
V
V
V
T
H
E
M
G
F
-
A
R
E
-
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
-------------------------------------------------------------------------------------------------------------------------------------
74
PsiBlast_CBE
55.11
36%
-66
- C1 -
2OLK
2
?
B:
[36-240]
--------------------
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
A
-
K
D
T
N
L
N
K
----
V
R
E
-
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
--
P
---
M
K
V
R
K
--
W
----
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
-
L
K
D
--
K
----
A
H
A
-
Y
P
D
--
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
G
-
M
T
M
V
V
V
T
H
E
M
G
F
-
A
R
E
-
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
-------------------------------------------------------------------------------------------------------------------------------------
79
PsiBlast_CBE
54.76
36%
-52
- C1 -
3C41
3
?
J:
[15-219]
--------------------
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
A
-
K
D
T
N
L
N
K
----
V
R
E
-
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
--
P
---
M
K
V
R
K
--
W
----
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
-
L
K
D
--
K
----
A
H
A
-
Y
P
D
--
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
G
-
M
T
M
V
V
V
T
H
E
M
G
F
-
A
R
E
-
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
-------------------------------------------------------------------------------------------------------------------------------------
75
PsiBlast_CBE
54.62
36%
-61
- C1 -
2OLK
1
?
A:
[36-240]
--------------------
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
A
-
K
D
T
N
L
N
K
----
V
R
E
-
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
--
P
---
M
K
V
R
K
--
W
----
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
-
L
K
D
--
K
----
A
H
A
-
Y
P
D
--
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
G
-
M
T
M
V
V
V
T
H
E
M
G
F
-
A
R
E
-
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
-------------------------------------------------------------------------------------------------------------------------------------
66
PsiBlast_CBE
54.11
36%
-57
- C1 -
2Q0H
4
?
B:
[36-240]
--------------------
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
A
-
K
D
T
N
L
N
K
----
V
R
E
-
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
--
P
---
M
K
V
R
K
--
W
----
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
-
L
K
D
--
K
----
A
H
A
-
Y
P
D
--
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
G
-
M
T
M
V
V
V
T
H
E
M
G
F
-
A
R
E
-
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
-------------------------------------------------------------------------------------------------------------------------------------
64
PsiBlast_CBE
53.86
36%
-47
- C1 -
3C4J
4
?
B:
[36-240]
--------------------
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
A
-
K
D
T
N
L
N
K
----
V
R
E
-
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
--
P
---
M
K
V
R
K
--
W
----
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
-
L
K
D
--
K
----
A
H
A
-
Y
P
D
--
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
G
-
M
T
M
V
V
V
T
H
E
M
G
F
-
A
R
E
-
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
-------------------------------------------------------------------------------------------------------------------------------------
76
PsiBlast_CBE
53.27
36%
-57
- C1 -
2OLJ
3
?
B:
[36-240]
--------------------
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
A
-
K
D
T
N
L
N
K
----
V
R
E
-
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
--
P
---
M
K
V
R
K
--
W
----
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
-
L
K
D
--
K
----
A
H
A
-
Y
P
D
--
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
G
-
M
T
M
V
V
V
T
H
E
M
G
F
-
A
R
E
-
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
-------------------------------------------------------------------------------------------------------------------------------------
93
PsiBlast_CBE
50.85
33%
-16
- C1 -
2ONJ
4
Y1866_STAAM
B:
[344-562]
-------
H
V
S
F
Q
Y
N
D
N
E
A
P
I
----
L
K
D
I
N
L
S
I
E
K
G
E
T
V
A
F
V
G
M
S
G
G
G
K
S
T
L
I
N
L
I
P
R
F
Y
D
V
T
S
G
Q
I
L
I
D
G
H
N
I
K
D
F
L
T
G
S
L
--------
R
N
Q
I
G
L
V
Q
Q
D
-
N
I
L
F
S
D
T
V
K
E
N
I
-
L
L
GR
P
---
T
A
T
D
E
EV
V
----
E
A
A
K
M
A
N
A
H
D
F
I
M
N
L
P
Q
G
Y
D
T
--
E
----
V
G
E
-
R
G
V
--
K
L
S
G
G
Q
K
Q
R
L
S
I
A
R
I
F
L
N
N
P
P
I
L
I
L
D
E
A
T
S
A
L
D
L
E
S
E
S
I
I
Q
E
A
L
D
V
L
S
--
K
D
R
T
T
L
I
V
A
H
R
-
L
S
-
T
I
T
-
H
A
D
K
I
V
V
I
E
N
G
H
I
---
V
E
T
G
T
H
R
E
L
----------------------------------------------------------------------------------------------------------------------------
95
PsiBlast_CBE
50.13
33%
-17
- C1 -
2HYD
3
Y1866_STAAM
B:
[344-562]
-------
H
V
S
F
Q
Y
N
D
N
E
A
P
I
----
L
K
D
I
N
L
S
I
E
K
G
E
T
V
A
F
V
G
M
S
G
G
G
K
S
T
L
I
N
L
I
P
R
F
Y
D
V
T
S
G
Q
I
L
I
D
G
H
N
I
K
D
F
L
T
G
S
L
--------
R
N
Q
I
G
L
V
Q
Q
D
-
N
I
L
F
S
D
T
V
K
E
N
I
-
L
L
GR
P
---
T
A
T
D
E
EV
V
----
E
A
A
K
M
A
N
A
H
D
F
I
M
N
L
P
Q
G
Y
D
T
--
E
----
V
G
E
-
R
G
V
--
K
L
S
G
G
Q
K
Q
R
L
S
I
A
R
I
F
L
N
N
P
P
I
L
I
L
D
E
A
T
S
A
L
D
L
E
S
E
S
I
I
Q
E
A
L
D
V
L
S
--
K
D
R
T
T
L
I
V
A
H
R
-
L
S
-
T
I
T
-
H
A
D
K
I
V
V
I
E
N
G
H
I
---
V
E
T
G
T
H
R
E
L
----------------------------------------------------------------------------------------------------------------------------
94
PsiBlast_CBE
49.72
33%
-15
- C1 -
2ONJ
4
Y1866_STAAM
A:
[344-562]
-------
H
V
S
F
Q
Y
N
D
N
E
A
P
I
----
L
K
D
I
N
L
S
I
E
K
G
E
T
V
A
F
V
G
M
S
G
G
G
K
S
T
L
I
N
L
I
P
R
F
Y
D
V
T
S
G
Q
I
L
I
D
G
H
N
I
K
D
F
L
T
G
S
L
--------
R
N
Q
I
G
L
V
Q
Q
D
-
N
I
L
F
S
D
T
V
K
E
N
I
-
L
L
GR
P
---
T
A
T
D
E
E
V
V
----
E
A
A
K
M
A
N
A
H
D
F
I
M
N
L
P
Q
G
Y
D
T
--
E
----
V
G
E
-
R
G
V
--
K
L
S
G
G
Q
K
Q
R
L
S
I
A
R
I
F
L
N
N
P
P
I
L
I
L
D
E
A
T
S
A
L
D
L
E
S
E
S
I
I
Q
E
A
L
D
V
L
S
--
K
D
R
T
T
L
I
V
A
H
R
-
L
S
-
T
I
T
-
H
A
D
K
I
V
V
I
E
N
G
H
I
---
V
E
T
G
T
H
R
E
L
----------------------------------------------------------------------------------------------------------------------------
96
PsiBlast_CBE
48.17
33%
-17
- C1 -
2HYD
3
Y1866_STAAM
A:
[344-562]
-------
H
V
S
F
Q
Y
N
D
N
E
A
P
I
----
L
K
D
I
N
L
S
I
E
K
G
E
T
V
A
F
V
G
M
S
G
G
G
K
S
T
L
I
N
L
I
P
R
F
Y
D
V
T
S
G
Q
I
L
I
D
G
H
N
I
K
D
F
L
T
G
S
L
--------
R
N
Q
I
G
L
V
Q
Q
D
-
N
I
L
F
S
D
T
V
K
E
N
I
-
L
L
GR
P
---
T
A
T
D
E
E
V
V
----
E
A
A
K
M
A
N
A
H
D
F
I
M
N
L
P
Q
G
Y
D
T
--
E
----
V
G
E
-
R
G
V
--
K
L
S
G
G
Q
K
Q
R
L
S
I
A
R
I
F
L
N
N
P
P
I
L
I
L
D
E
A
T
S
A
L
D
L
E
S
E
S
I
I
Q
E
A
L
D
V
L
S
--
K
D
R
T
T
L
I
V
A
H
R
-
L
S
-
T
I
T
-
H
A
D
K
I
V
V
I
E
N
G
H
I
---
V
E
T
G
T
H
R
E
L
----------------------------------------------------------------------------------------------------------------------------
92
PsiBlast_CBE
40.93
31%
-31
- C1 -
4S0F
2
?
A:
[504-699]
-----------------------
V
L
K
N
I
N
L
T
I
P
K
G
K
T
V
A
I
V
G
E
S
G
S
G
K
T
T
L
A
K
L
L
M
N
F
Y
S
P
E
K
G
D
I
L
I
N
G
---
H
S
I
K
N
I
S
L
E
L
----
I
R
K
K
-
I
A
F
V
S
Q
D
V
F
I
F
S
G
-
T
V
K
E
N
L
-
C
L
--
G
NEN
V
D
M
D
E
--
I
----
I
K
A
A
K
M
A
N
A
H
D
F
I
E
K
L
P
-
L
K
Y
DT
F
----
L
N
E
-
S
G
A
--
N
L
S
E
G
Q
K
Q
R
L
A
I
A
R
A
L
L
K
K
P
D
I
L
I
L
D
Q
A
T
S
N
L
D
S
I
T
E
N
H
I
K
D
A
I
Y
G
L
--
E
D
D
V
T
V
I
I
I
A
H
R
-
L
S
-
T
I
V
-
N
C
D
K
I
Y
L
L
K
D
G
------------------------------------------------------------------------------------------------------------------------------------------
98
PsiBlast_CBE
40.72
31%
-24
- C1 -
2FF7
1
A:
[25-224]
------------------------
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
--------
H
D
L
A
L
AD
P
N
W
L
R
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
S
I
I
D
N
I
-
S
L
--
A
NPG
M
S
V
E
K
--
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
L
R
E
G
Y
N
-
T
----
I
----
V
G
E
-
Q
G
A
--
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
--
K
G
R
T
V
I
I
I
A
H
R
-
L
S
-
T
V
K
-
N
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
-------------------------------------------------------------------------------------------------------------------------------------
97
PsiBlast_CBE
39.05
31%
-23
- C1 -
2PMK
1
A:
[21-220]
------------------------
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
--------
H
D
L
A
L
AD
P
N
W
L
R
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
S
I
I
D
N
I
-
S
L
--
A
NPG
M
S
V
E
K
--
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
S
E
L
R
E
G
Y
N
-
T
----
I
----
V
G
E
-
Q
G
A
--
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
--
K
G
R
T
V
I
I
I
A
H
R
-
L
S
-
T
V
K
-
N
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
-------------------------------------------------------------------------------------------------------------------------------------
91
PsiBlast_CBE
37.99
31%
-35
- C1 -
4S0F
2
?
B:
[504-699]
-----------------------
V
L
K
N
I
N
L
T
I
P
K
G
K
T
V
A
I
V
G
E
S
G
S
G
K
T
T
L
A
K
L
L
M
N
F
Y
S
P
E
K
G
D
I
L
I
N
G
---
H
S
I
K
N
I
S
L
E
L
----
I
R
K
K
-
I
A
F
V
S
Q
D
V
F
I
F
S
G
-
T
V
K
E
N
L
-
C
L
--
G
NEN
V
D
M
D
E
--
I
----
I
K
A
A
K
M
A
N
A
H
D
F
I
E
K
L
P
-
L
K
Y
DT
F
----
L
N
E
-
S
G
A
--
N
L
S
E
G
Q
K
Q
R
L
A
I
A
R
A
L
L
K
K
P
D
I
L
I
L
D
Q
A
T
S
N
L
D
S
I
T
E
N
H
I
K
D
A
I
Y
G
L
--
E
D
D
V
T
V
I
I
I
A
H
R
-
L
S
-
T
I
V
-
N
C
D
K
I
Y
L
L
K
D
G
------------------------------------------------------------------------------------------------------------------------------------------