@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu35630: (2016-07-30 )
MKSCKQLIVCSLAAILLLIPSVSFAADSNISVKLLNYIGNKSSISLSPTGFYKVTGDNVAVTDRFAGASRYETATLASNSQWKNPNTVILVNRDIFIDALPVIPLAKKLNAPVLFTQPDTLTKTTERQIAKFNPDNILIIGGARSISKDVENKLKSYGAVKRISGKNRYVLSENIAKQMGSYDKAIVVTGRVFQDALAIAPYAAAHGYPILLTEKDKLPDYDLPKQVIIIGSSFSVSDSVENQIKKTSTVQRIPGSTRYELTANIIKQLKLKADKVVMTNGTKYADVLIGASLASKKNSQILFVKQDSVPAAAKSITKDKATYAYDFIGSTSSISAEVENSLADEFYLADGGTYNLKINSGKLNLENIKTYGNSLRIKPENYSTSNRISLDGKQYLGTVNFSIESTKYIRPVNENIPFEDYLKGVIPNEMPASWSLEALKAQTVAARTYSITKTGTTVPDTTAFQVYGGYSWNSNTNKAVEQTKGKVLKYNGSLITAAYSSSNGGYTEASNEVWSSSVPYLIAKKDTKDPQIGWTLTLSKQQLDTKSLDLTKPSSWWSSATETDSARLSGVKNWILKNKETSADSVKIASIDDLSFSGTTQGQRAKTASMKVKYFVKSSTGSYNLSKITTISVPTSELRTMIGATVFKSTYVTVKKDTSKYTISGKGYGHGIGMSQYGAKARAEAGDSYSSILKFYYPGTTLTSY
Atome Classification :
(20 SA)
-------.........-----10.-.......-------20..---....-..--30.......-.40........50........60......-..70........80........90.-.......----100..---------------------------.....-110..---------.....120.....-..130-.-......140..-----.......150......--.160....-..-.170.....-----.-------.-180------------.......190---....-....-.200.....-..210--....----...220..---.......230.......240..----..----.--..250---......-..260...--....270..-----.....280....--...------290..--.....300.......310.......320-----.....--...330---------.........340.------------......350------.......360....-...370.----...--...380--....---...390---........400.......410......--.420-........430.......440...-----....450-------..-------....---.460......---------.470------------......---.480.-..------....------490.......500.......510..--------------------.....520.......---530.......540.--------------......550.......560.......570.......580....-------...590.......600.......610.......620.......630.......640.......650.......660.......-----670.......680...----....690.......700...----------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------M
K
S
C
K
Q
L
I
V
-----
C
S
L
-
A
A
I
L
L
L
I-------PSVS---FAAD-SN--
I
S
V
K
L
L
N
YI-GNKS
S
I
S
LSPT
G
F
Y
K
VTGD
N
V
A
V
T
DRFAG-ASR
Y
E
T
A
T
LASNSQWKNP
N
T
V
I
L
V
N-R
D
I
F
I
DA----LPVI
P
---------------------------
L
A
K
KL-NA
P
V
L
---------
F
TQPDTLT
K
T
T
E
R
-
Q
I
AKF-N-PD
N
I
L
I
I--GG-----
A
R
S
I
S
K
D
V
E
N
K
L
K
S
YG--
A
V
KRISGK-N
R
-
Y
V
L
S
E
N
I
A
K
-----
Q
-------M-GSY------------D
K
A
I
V
V
T
G
-----
R
V
F
Q
-
D
A
L
A
-IAPYAAAHG-
Y
P
I
L
L
--TEKD----KLPD--YD---LP
K
Q
V
I
I
IGSSFSV
S
D
S
V
E
N
Q
I
----
K
K----T--
S
T
V
Q----RIPGST-
R
Y
E
L
T
A
N
I
--
I
K
Q
L
KLKA
D
-----
K
V
V
MTNGT
K
Y
A
D
--
V
L
I------GASLA--SKKN
S
Q
I
L
F
V
KQDSV
P
A
A
A
K
SITKDK
A
------
T
Y
A
Y
D
--FIGS-----------TS
S
I
S
A
E
V
E
N
SLA------------
D
E
F
Y
LADG
G
------
T
Y
N
L
K
INSG
K
L
N
L
E
-
N
I
K
TYG
N
----
S
L
R
--IKPENY--STS
N
---
R
I
SLD----G
K
Q
Y
L
G
T
V
N
F
S
IES
T
K
Y
I
RPVNENI
P
F
--
E
D
Y
--
L
K
G
VIPNEMPASWS
L
E
A
L
K
A
Q
T
V
A
-----
A
R
T
Y
S
I
T-------KT-------GTTV---PDT
T
A
F
Q
V
Y
G
---------GYSW------------NSNT
N
K
---
A
V
E
Q
T-K
G
------
K
V
L
K
------YNG
S
L
I
T
A
A
YSSSNGGYTEASNEVW--------------------SSSV
P
Y
L
I
AKKDTKD---PQ
I
G
W
T
L
T
L
SKQQL--------------DTKSLDLTKP
S
S
WWSSATET
D
S
A
R
L
S
G
V
K
N
W
I
LKNKETSAD
S
V
-------
K
I
A
S
IDDLSFSGTTQGQRAKTA
S
M
K
V
K
Y
F
V
KSSTGSY
N
L
S
K
I
T
T
I
SV
P
T
S
E
L
R
T
M
I
G
A
T
VFK
S
T
Y
V
T
V
KKDT
S
K
Y
T
I
SGKGYG-----HGI
G
M
S
QYGAKARAEA----GD
S
Y
S
S
I
L
K
F
YYPGTTLTSY----------
36
Fugue
68.39
17%
60
- C3 -
4ZUZ
-
?
A:
[8-864]
D
V
I
K
F
K
E
P
E
R
C
D
Y
L
Y
V
-----
D
E
N
-
N
K
V
H
I
L
L
-------
P
I
V
G
GDE
I
G
L
D
-
N
T
C
Q
T
A
V
E
L
I
T
F
F
Y
G
S
A
H
S
G
V
T
K
Y
S
A
E
H
Q
L
S
E
Y
K
R
Q
L
E
E
D
I
K
A
-
I
N
S
Q
K
K
I
S
P
H
A
Y
D
D
L
L
K
E
K
I
E
R
L
Q
Q
-
I
E
K
Y
I
E
L
----
I
Q
V
L
K
K
QYDEQN
D
I
R
Q
L
R
TGGIPQLP
S
G
V
K
E
I
I
K
S
S
E
-
N
A
F
A
V
R
L
S
P
YDNDK
F
T
R
F
D
D
P
L
F
N
V
K
R
-
N
I
S
K
Y
-
D
T
P
S
R
Q
A
P
I
--
P
I
-----
Y
E
G
L
G
Y
R
L
R
S
T
L
--
F
P
--
E
D
K
T
P
T
P
I
-
N
K
-
K
S
L
R
D
K
V
K
S
-----
T
-------
V
-
L
S
H
YKDEDRIDGEK
K
D
E
K
L
N
E
L
I
-----
T
N
L
Q
-
N
E
L
V
-
K
E
L
V
K
S
D
P
Q
-
Y
S
K
L
S
--
L
S
K
D
PRG
K
E
I
N
Y
--
D
Y
---
L
V
N
S
L
M
L
V
D
N
D
S
E
I
G
D
W
I
D
T
I
L
----
D
A
----
T
VD
S
T
V
W
----
A
V
Q
A
S
S
-
P
F
Y
Q
G
A
K
E
--
I
S
S
-
D
R
D
A
D
-----
K
I
S
I
R
V
Q
Y
L
L
A
E
--
A
N
I
------
Y
C
K
T
N
KL
S
D
A
N
F
G
E
F
F
D
K
E
P
H
A
T
E
I
A
K
R
V
K
E
G
F
T
Q
GAD
I
E
P
I
I
Y
D
--
Y
I
N
S
NHAELGLKSPL
T
G
K
Q
Q
Q
E
I
T
D
K
F
T
K
H
Y
N
T
I
K
ESPHF
D
E
F
F
V
A
D
P
D
KKGN
I
F
S
H
Q
G
R
I
S
C
H
F
L
D
F
F
-
T
R
Q
T
K
G
K
HPLG
D
L
A
--
S
H
Q
E
A
L
Q
E
G
T
S
N
---
R
L
H
H
K
N
E
V
V
A
Q
G
Y
E
K
L
D
Q
F
K
K
E
V
V
K
L
L
A
E
-
N
K
P
K
E
L
--
L
D
Y
--
L
V
A
T
S
P
T
G
V
P
N
Y
S
M
L
S
K
E
T
Q
N
Y
I
A
Y
NRN
W
P
A
I
Q
K
E
L
-------
E
K
-------
A
T
S
I
---
P
E
S
Q
K
Q
D
L
S
R
---------
L
L
S
R
------------
D
N
L
Q
H
D
---
N
L
S
A
I
-
T
W
S
KYSSK
P
L
L
D
------
V
E
L
N
K
I
A
E
G
L
E
L
T
A
K
I
Y
N
E
K
R
G
R
E
W
WFAGSR
N
E
A
R
K
T
Q
C
E
E
L
Q
R
V
S
K
E
I
N
T
L
L
Q
S
E
S
L
T
K
---
S
Q
V
L
E
K
V
L
N
S
I
E
T
L
--------------
D
K
I
D
R
D
I
S
A
E
S
N
W
F
Q
S
T
L
Q
K
E
V
R
L
F
R
D
Q
L
K
D
I
C
Q
L
D
K
Y
Y
F
K
S
T
-------
K
L
----
D
E
I
I
S
L
E
M
E
E
Q
F
Q
K
I
Q
D
P
A
V
Q
Q
I
V
R
D
L
P
S
H
C
H
N
D
E
A
I
E
F
F
K
T
L
N
P
E
E
A
A
K
V
A
S
Y
L
S
L
E
Y
R
E
I
N
K
S
T
D
K
K
T
L
L
E
Q
D
I
P
-----
R
L
F
K
E
V
N
T
Q
L
L
S
K
L
K
E
E
KAI
D
E
Q
V
H
E
K
L
S
Q
L
A
D
K
I
A
P
E
H
F
T
R
N
N
I
I
K
W
S
T
37
Fugue
64.88
15%
37
- C2 -
4LXR
11
TOLL_DROME
A:
[1-773]
----SFG
R
D
A
C
S
E
M
S
I
D
GL
C
Q
C
A
P
I
M
S
E
Y
E
I
I
C
PANAEN
P
T
F
R
---
L
T
I
Q
-
P
K
--
D
Y
V
Q
I
M
C
N
L
-
T
D
T
T
D
Y
Q
Q
L
P
K
K
L
R
I
G
E
V
D
R
V
Q
M
R
-
R
C
M
L
-
P
G
H
T
P
I
A
S
I
L
D
Y
L
G
I
V
S
P
T
T
L
I
F
E
S
-
D
N
L
G
M
N
-----
I
T
R
Q
H
---------------------------
L
D
R
L
H
-
G
L
K
R
F
---------
R
F
T
T
R
R
L
T
H
I
P
A
N
-
L
L
T
D
M
R
N
-
L
S
H
L
E
L
R
--
A
N
-----
I
E
E
M
P
S
H
L
F
D
D
L
E
N
L
E
--
S
I
E
F
G
S
N
K
-
L
R
--
Q
M
P
R
G
I
F
G
-----
K
-------
M
-
P
K
L
------------
K
Q
L
N
L
W
S
N
-----
Q
L
H
N
L
T
K
H
D
-
F
E
G
A
T
S
V
L
G
-
I
D
I
H
D
--
N
G
I
E
----
Q
L
P
H
DV
F
A
---
H
L
T
N
V
T
D
I
N
L
S
A
N
L
F
R
S
L
P
Q
G
L
FDHN
K
H
----
L
--
N
E
V
R
LMNN
R
V
P
L
A
T
L
P
S
R
L
F
A
N
Q
PE
L
Q
I
L
R
L
R
A
E
LQSLP
G
D
L
F
E
H
S
T
Q
I
T
N
--
I
S
L
------
G
D
N
L
L
--
K
T
L
P
A
T
L
L
---
E
H
Q
V
N
L
L
S
L
D
L
S
N
N
R
L
------
T
H
L
P
D
SL
F
A
H
T
-----------
T
N
L
T
D
L
R
L
E
D
N
L
L
------------
T
G
I
--------------
S
G
D
I
F
S
N
L
G
N
L
V
-
T
L
V
M
S
R
N
----
R
L
R
T-
I
D
S
R
A
F
--
V
S
T
N
GLR
H
L
H
L
D
----
H
N
D
----
I
D
L
Q
Q
P
L
L
D
I
M
L
Q
T
Q
I
N
S
P
F
--
G
Y
M
HG
L
L
T
L
N
L
R
N
N
S
I
I
F
V
Y
N
D
W
K
N
T
M
L
Q
-----
L
R
E
L
D
L
S
-------
Y
N
-------
N
I
S
S
---
L
G
------
Y
E
---------
D
L
A
F
------------
L
S
Q
N
R
L
---
H
V
N
M
T
-
H
N
------
K
I
R
R
I
A
L
P
ED
V
N
N
N
L
V
H
V
D
L
N
D
---------
N
P
L
V
CD------------------
C
T
I
L
W
F
I
Q
L
V
R
G
V
H
K
---
P
Q
Y
S
R
Q
F
K
L
R
T
D
R
L
VCSQPNVLEGTPVR
Q
I
E
P
Q
T
L
I
C
P
L
D
F
S
K
C
P
R
G
C
N
C
H
V
R
T
Y
D
K
A
L
V
I
N
C
H
S
G
N
L
T
H
V
PRLPNLH
K
N
M
Q
L
M
E
L
H
L
E
N
N
T
L
L
R
L
P
S
A
N
T
P
G
Y
E
S
V
T
S
L
H
L
A
G
N
N
L
T
S
I
D
V
D
Q
L
P
T
N
L
T
H
L
D
I
S
W
N
H
L
Q
M
L
N
A
T
V
L
G
F
L
N
W
R
S
V
K
L
S
G
N
P
WMCDC
T
A
K
P
L
L
L
F
T
Q
D
N
F
E
R
I
----
G
D
--
R
N
E
M
M
C
V
N
A
P
T
R
M
V
E
L
STNDICP---
35
Fugue
62.79
15%
2
- C8 -
5F9H
6
DDX58_HUMAN
A:
[11-692]
-------
F
K
P
R
N
Y
Q
L
E
-----
L
A
L
-
P
A
M
K
G
---------
K
N
T
I
---
I
C
A
P
-
T
G
--
C
G
K
T
F
V
S
L
L
-
I
C
E
H
H
L
K
K
F
P
Q
G
Q
---
K
G
K
V
V
F
F
A
N
Q
----
I
P
V
Y
E
Q
Q
K
S
V
F
S
K
Y
F
E
R
H
G
Y
R
V
T
G
I
-
S
G
A
T
A
E
N
----
V
P
V
E
Q
---------------------------
I
V
E
---
N
N
D
I
I
---------
I
L
T
P
Q
I
L
V
N
N
L
K
K
G
T
I
P
S
L
-
S
-
I
F
T
L
M
I
F
--
D
E
-----
C
H
N
T
S
K
Q
H
P
Y
N
M
I
M
F
N
--
Y
L
D
Q
K
L
G
G
-
S
-----
S
G
P
L
P
Q
-----
V
-------
I
-
G
L
T
------------
A
S
V
G
V
G
D
A
-----
K
N
T
D
-
E
A
L
D
Y
I
C
K
L
C
A
S
L
D
-
A
S
V
I
A
--
T
V
K
H
----
N
L
E
E
--
L
E
Q
V
V
Y
K
P
Q
K
F
F
R
K
V
E
S
R
I
S
D
K
F
K
Y
I
I
----
A
Q
L
M
R
D
T
--
E
S
L
A
----
K
R
I
C
K
D
-
L
R
E
F
G
T
Q
K
--
Y
E
Q
W
I
V
T
V
Q
-----
K
A
C
M
V
F
Q
M
P
D
K
D
--
E
E
S
------
R
I
C
K
A
--
L
F
L
Y
T
S
H
L
R
K
Y
N
D
A
L
I
I
S
E
H
A
R
M
K
D
A
L
------
D
Y
L
K
D
--
F
F
S
N
-----------
V
R
A
A
F
D
E
I
E
Q
D
L
T
------------
Q
R
F
---
E
E
K
------
L
Q
E
L
E
S
V
S
R
D
P
S
N
E
-
N
-----------------------------------------
P
K
L
E
D
L
C
F
I
L
Q
E
E
Y
H
L
N
P
E
T
I
T
I
L
F
V
K
T
R
A
--
L
V
D
A
L
K
N
W
I
E
G
N
P
K
L
S
F
L
K
P
G
I
L
T
-----
G
R
D
H
N
I
L
-------
I
A
-------
T
S
V
A
DEG
I
D
I
A
Q
C
N
L
V
I
---------
L
Y
E
Y
------------
V
G
N
V
I
K
---
M
I
Q
T
R
G
R
G
------
R
A
R
G
------
S
K
C
F
L
L
T
-------------
S
N
A
G
V
--------------------
I
E
K
E
Q
I
N
M
Y
K
E
K
M
M
N
---
D
S
I
L
R
L
Q
T
W
D
E
A
V
F
--------------
R
E
K
I
L
H
I
Q
T
H
E
K
F
I
R
D
S
Q
P
K
P
V
P
D
K
E
N
K
K
L
L
C
R
K
C
K
A
L
A
C
Y
T
A
-------
D
V
R
V
I
E
E
C
H
Y
--
T
V
L
G
D
A
F
K
E
C
F
V
S
R
P
H
P
K
P
K
Q
F
S
S
--
F
E
K
R
A
K
I
F
C
A
R
Q
N
C
S
H
D
W
G
I
H
V
K
Y
K
T
F
E
I
P
V
I
K
I
E
S
F
V
V
E
D
I
A
T
G
-----
V
Q
T
-------------------
L
Y
S
K
W
K
D
F
H
F
E
K
I
P
F
D
P
A
E---------
33
Fugue
61.49
14%
33
- C8 -
4MTK
20
?
A:
[5-640]
----------
R
L
V
Q
V
D
-----
C
P
L
-
G
P
D
V
L
L
L
-------
Q
R
M
E
---
G
R
E
E
L
G
R
--
L
F
A
Y
E
L
H
L
V
-
S
E
N
P
N
L
P
L
E
Q
-----
L
L
G
K
P
M
S
L
S
L
E
L
P
G
G
S
R
R
F
F
H
G
I
V
A
R
C
S
Q
V
A
G
H
G
Q
F
------
A
G
Y
Q
A
T
----
L
R
P
W
P
---------------------------
W
L
L
T
R
-
T
S
D
C
R
---------
I
F
Q
N
Q
S
V
P
E
I
I
K
Q
-
V
F
R
N
L
-
G
-
F
S
D
F
E
D
A
LT
R
P
-----
Y
R
E
W
E
Y
C
V
Q
Y
R
E
T
S
F
D
--
F
I
S
R
L
M
E
Q
-
E
G
I
Y
Y
W
F
R
H
-------------------
E
Q
------------
K
R
H
I
L
V
L
S
-----
D
A
Y
G
-
A
H
R
S
-
P
G
G
Y
A
S
V
P
Y
-
Y
P
P
T
L
GH
R
E
R
D
----
H
F
F
D
--
W
Q
---
M
A
R
E
V
Q
--
P
G
S
L
T
L
N
D
Y
D
F
Q
R
P
----
G
A
----
R
--
L
E
V
R
----
S
N
I
A
R
P
-
H
A
A
A
D
Y
P
L
--
Y
D
---
Y
P
G
E
-----
Y
V
Q
S
Q
D
G
E
Q
Y
A
R
--
N
R
I
------
E
A
I
Q
A
--
Q
H
E
R
V
R
L
R
G
V
--------
V
R
G
I
G
---
A
------
G
H
L
F
R
--
L
S
G
Y
-----------
P
R
--------
D
D
Q
------------
N
R
E
Y
L
V
V
G
A
------
E
Y
R
V
V
Q
E
L
S
Q
F
E
S
E
L
D
C
I
D
A
S
Q
----
S
F
R
--
L
L
P
Q
T
P
--
V
P
V
V
---
R
G
P
Q
T
----
A
V
V
-
V
G
P
K
G
E
E
I
W
T
D
Q
Y
G
R
-
V
K
V
H
F
H
W
--
D
R
H
--
D
Q
S
---
N
E
N
S
S
C
W
----
I
R
V
S
Q
A
W
-----
A
G
K
N
W
G
S
-------
M
Q
-------
I
P
R
I
---
G
Q
E
V
I
V
S
F
L
E
---------
G
-
D
P
------------
D
R
P
I
I
T
---
G
R
V
Y
N
-
A
E
------
Q
T
V
P
------
Y
E
----
L
P
A
N
A
T
Q
S
G
M
K
S
R
S
S
K
G
G
T
--------------------
P
A
N
F
N
E
I
R
M
E
D
K
K
G
A
---
E
Q
L
Y
I
H
A
E
R
N
Q
D
N
L
--------------
V
E
N
D
A
S
L
S
V
G
H
D
R
N
K
S
I
G
H
D
E
L
A
R
I
G
--------
N
N
R
T
R
A
V
K
L
-------
N
D
T
L
L
V
G
G
A
K
S
D
S
V
T
G
T
Y
L
I
E
A
G
A
Q
I
R
L
V
C
G
K
S
V
V
E
F
N
A
D
G
T
I
N
I
S
---------------
G
S
A
F
N
L
Y
A
S
G
N
G
N
I
D
T
G
G
R
L
D
L
-----
N
S
G
G
A
S
E
V
D
A
K
G
K
G
V
Q
----
G
T
I
D
G
Q
V
Q
A
M
F
P
P
P
----------------
21
HHSearch
52.19
30%
18
- C- -
4RWR
-
?
A:
[63-328]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
Y
R
E
-
K
Q
K
K
V
E
S
-
L
P
M
--
E
E
Y
--
V
T
G
V
V
A
S
E
M
N
A
S
F
E
I
E
A
L
K
A
Q
A
L
A
-----
A
R
T
F
V
V
Q
-------
R
M
L
S
GGKKN
N
A
D
V
---
T
D
T
--
D
Q
V
Y
K
---------
S
K
E
E
L
K
K
Q
W
GNN
Y
E
N
N
L
K
K
I
E
E
---
A
V
S
K
T
-
A
G
------
Q
V
L
T
------
Y
E
G
K
P
I
S
A
S
F
F
S
T
S
N
G
R
T
E
N
A
A
D
Y
W
--------------------
G
N
D
Y
P
Y
L
K
S
V
D
S
P
W
D
QAS
P
K
F
T
S
E
Q
I
F
T
V
A
D
F
--------------
Q
K
R
-
L
G
V
K
---------------------------------
V
L
-------
A
D
G
K
V
--
G
D
I
K
G
R
T
E
G
K
R
V
K
D
V
A
F
------------------
Q
G
K
T
L
T
G
R
D
V
R
D
K
L
E
---
L
R
S
S
D
F
T
W
K
Q
E
G
D
K
I
V
V
T
T
K
G
F
G
-----
H
G
V
G
M
S
Q
Y
G
A
N
G
M
A
A
E
----
G
K
K
Y
T
D
I
V
A
H
Y
Y
K
G
V
E
I
K
T
M
----------
1
PsiBlast_PDB
47.09
29%
60
- C- -
4RWR
-
?
A:
[72-325]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
S
L
P
M
--
E
E
Y
--
V
T
G
V
V
A
S
E
M
N
A
S
F
E
I
E
A
L
K
A
Q
A
L
A
-----
A
R
T
F
V
V
Q
R
M
L
S
GGK
K
N
-------
N
A
D
V
---
T
D
T
--
D
Q
V
Y
K
S
K
E
E
L
K
K
Q
W
G
N
N
Y
------------
E
N
N
L
K
K
I
E
E
A
V
S
K
T
-
A
G
------
Q
V
L
T
------
Y
E
G
K
P
I
S
A
S
F
F
S
T
S
N
G
R
T
E
N
A
A
D
Y
W
--------------------
G
N
D
Y
P
Y
L
-----------------------------------------
K
S
V
D
----
S
P
W
D
Q
A
S
P
K
F
T
S
E
Q
I
F
T
V
A
D
F
---
Q
K
R
L
G
V
K
V
L
-------
A
D
G
K
V
G
D
I
K
--
G
R
T
E
G
K
R
V
K
D
----
V
A
F
Q
G
K
T
L
T
G
R
D
V
R
D
K
L
--------
E
L
R
---------
S
S
D
F
T
W
K
Q
E
G
D
K
I
V
V
T
T
K
G
F
G
-----
H
G
V
G
M
S
Q
Y
G
A
N
G
M
A
A
E
----
G
K
K
Y
T
D
I
V
A
H
Y
Y
K
G
V
E
I
-------------
39
Fugue
44.10
18%
50
- C4 -
4R1D
1
?
A:
[45-561]
-------
Q
T
A
---------------
P
L
P
V
I
F
I
-------
P
G
I
-------------
M
G
T
N
L
R
N
K
--
A
D
K
S
E
V
W
R
P
P
N
G
L
W
P
M
D
D
L
F
A
S
I
G
A
L
W
T
W
-
A
W
R
G
P
K
A
R
Q
E
L
L
K
A
E
Q
-----
V
E
V
D
-
D
Q
G
T
I
D
V
GQSG
L
S
E
E
A
---------------------------
A
R
L
R
G
-
W
G
K
V
M
---------
R
S
A
Y
N
P
V
M
G
L
M
E
R
-
R
L
D
N
I
-
V
-
S
R
R
E
L
Q
A
--
W
W
-----
N
D
E
A
L
S
P
P
G
D
Q
G
E
E
Q
G
--
K
V
G
P
I
D
----------
E
E
E
L
L
-----
R
-------
A
-
S
R
Y
------------
Q
F
D
V
W
C
A
G
YNWLQ
S
N
R
Q
-
S
A
L
D
-
V
R
D
Y
I
E
N
T
V
-
L
P
F
Y
Q
--
K
E
C
G
----
L
D
P
E
--
Q
M
---
R
R
M
K
V
I
L
V
T
H
S
M
--
G
G
L
V
A
R
A
L
----
T
Q
----
L
--
H
G
Y
E
----
R
V
L
G
V
V
-
H
G
V
Q
P
A
T
---------------------
G
S
S
T
I
Y
H
H
--
M
R
C
------
G
------
Y
E
G
I
A
Q
V
V
L
G
R
N
-----------------------
A
G
E
--
V
T
A
I
-----------
V
A
N
S
A
G
A
L
E
L
A
P
S
------------
A
E
Y
R
--
E
G
R
------
P
W
L
F
L
C
D
A
Q
G
Q
V
L
K
-
D
I
D
G
-------------
K
P
R
A
Y
--
P
Q
N
Q
-------------------------------
D
P
Y
E
E
I
Y
K
--
N
T
T
--
W
Y
G
L
V
P
E
Q
N
S
Q
Y
L
D
M
S
D
K
K
E
G
L
------------------------------------------------------------------------
R
V
G
P
R
D
---
N
F
E
D
L
-
I
D
------
S
I
A
N
------
F
H
G
E
L
S
A
A
G
Y
H
S
E
T
Y
A
H
Y
G
A
D
D
S
----------------------
R
H
S
W
R
D
L
I
W
K
G
D
P
T
P
---
L
E
-----
T
P
G
A
T
L
N
--------------
D
D
E
N
G
T
Y
---
N
S
W
F
R
R
----------
G
L
P
T
I
V
Q
G
P
L
E
T
G
N
P
L
D
-------
A
S
G
S
G
G
D
E
T
V
P
-
T
D
S
G
Q
A
P
A
L
A
G
V
K
A
S
F
R
H
G
S
K
G
K
G
Q
A
N
T
K
--------------------------------------
R
G
Y
E
-----
H
Q
E
S
Y
N
D
----
A
R
A
Q
W
----
A
A
L
Y
G
-
V
I
K
I
T
----
Q
L
A
D
W
----------
32
Fugue
41.62
15%
54
- C6 -
3RFY
-
CYP38_ARATH
A:
[78-433]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
-----
G
I
L
L
V
A
N
P
V
I
P
D
V
S
V
L
I
S
GPPIK
D
P
E
A
L
--
L
R
Y
A
L
P
I
D
N
K
A
I
R
E
V
Q
K
P
L
E
D
I
T
D
S
L
K
------
I
A
G
V
K
--
A
L
D
S
-----------
V
E
R
N
V
R
Q
A
S
R
T
L
Q
------------
Q
G
K
S
I
I
V
A
G
------
F
A
E
S
K
K
D
H
G
N
E
M
I
E
-
K
L
E
A
G
M
Q
----
D
M
L
KI
V
E
D
R
K
R
--
D
A
V
A
---
P
K
Q
K
E
----
I
L
K
Y
V
G
G
I
E
E
D
M
V
D
-
G
F
P
Y
E
V
P
E
E
Y
R
N
--
M
P
L
--
L
K
G
----
R
A
S
V
D
M
K
V
K
I
K
D
N
P
N
I
E
-----
D
C
V
F
R
I
V
-------
L
D
-------
G
Y
N
A
---
P
V
T
A
G
N
F
V
D
L
---------
V
E
R
H
------------
F
Y
D
G
M
E
----
I
Q
R
S
-
D
G
------
F
V
V
Q
------
T
G
D
P
------
E
G
P
A
E
G
F
I
D
P
S
T
E
K
---------------------
T
R
T
V
P
L
E
I
M
V
T
G
E
K
T
---
P
F
Y
G
S
T
L
E
E
L
G
L
Y
K
--------------
A
Q
V
V
I
P
F
N
A
F
G
T
M
A
M
A
R
E
E
F
E
N
D
S
G
S
S
Q
V
F
W
L
L
K
E
S
E
L
T
P
S
N
S
-------
N
I
L
D
G
R
Y
A
V
F
G
Y
V
T
D
N
E
D
-
F
L
A
D
L
K
V
G
D
V
I
E
S
I
Q
V
V
S
G
L
E
N
L
A
N
P
S
Y
-------------------------------------------------------------------------------------------
25
HHSearch
39.04
22%
-113
* C7 *
5A6S
-
?
A:
[225-291]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
-
D
Q
R
A
-
A
E
Y
L
A
D
R
L
A
-
C
P
T
I
N
--
N
A
R
K
----
F
D
Y
----
S
---
N
V
K
N
V
Y
A
V
G
G
N
K
E
-------
Q
Y
----
T
S
-------
Y
L
T
T
----
L
I
A
G
S
T
-
R
Y
T
T
M
Q
A
V
--
L
D
Y
I
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
38.66
21%
-84
- C9 -
4GIC
1
HISX_METCA
A:
[173-283]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
N
A
L
V
L
A
-
A
A
Y
I
S
-
G
-
V
D
R
V
F
R
I
--
G
G
-----
A
Q
A
V
A
A
L
A
Y
G
T
-
E
T
V
P
--
R
V
D
K
I
V
G
P
G
N
I
-
Y
V
A
T
A
K
K
L
V
-----
F
GQ
V
G
I
D
M
V
A
G
P
S
------------
E
I
L
V
I
S
D
G
-----
R
T
D
P
-
D
W
I
A
-
M
D
L
F
S
Q
A
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
38.59
22%
-74
* C9 *
4G09
3
HISX_BRUSU
A:
[167-260]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
L
N
P
L
V
L
V
-
A
A
R
L
A
-
G
-
V
S
E
I
Y
R
V
--
G
G
-----
A
Q
A
I
A
A
L
A
Y
G
T
-
E
T
I
R
--
P
V
A
K
I
V
G
P
G
N
A
-
Y
V
A
A
A
K
R
I
V
-----
F
GTVGIDM
I
A
G
P
S
------------
E
V
L
I
V
A
D
K
-----
D
N
N
P
-
D
W
I
A
-
A
D
L
L
A
Q
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
38.28
20%
-109
- C7 -
2N3Z
-
?
A:
[36-81]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
Q
V
I
K
-
E
I
Q
K
K
-
G
-
V
Q
K
V
V
L
V
--
G
---------
V
S
E
K
L
L
Q
K
I
K
Q
E
A
N
V
Q
V
Y
R
V
T
S
N
-
D
E
-
L
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
37.52
26%
-112
- C7 -
5A6S
-
?
A:
[252-290]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
-
V
K
N
V
Y
A
V
--
G
G
-----
N
K
E
-------
Q
Y
T
S
Y
---
L
T
T
L
I
A
G
S
-
T
R
-
Y
T
T
M
Q
A
V
L
D
-----
Y
-------
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
35.89
29%
-69
- C7 -
1XQ1
-
TRNH1_ARATH
A:
[17-115]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
L
V
T
--
G
G
-----
T
K
G
I
G
H
A
I
V
E
E
F
A
G
F
G
--
A
V
I
H
T
C
A
R
-
N
E
-
Y
E
L
N
E
C
L
S
K
-----
W
-------
Q
----------------
K
K
G
F
Q
V
T
G
-----
S
V
C
D
-
A
S
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
35.75
29%
-73
- C7 -
2Q45
-
TRNH1_ARATH
A:
[17-115]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
L
V
T
--
G
G
-----
T
K
G
I
G
H
A
I
V
E
E
F
A
G
F
G
--
A
V
I
H
T
C
A
R
-
N
E
-
Y
E
L
N
E
C
L
S
K
-----
W
-------
Q
----------------
K
K
G
F
Q
V
T
G
-----
S
V
C
D
-
A
S
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
34.00
36%
-22
- C1 -
2LQH
-
B:
[102-112]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
M
S
H
Y
G
N
Q
T
L
Q
------------------------------------
22
HHSearch
33.43
14%
-12
- C7 -
4CU5
-
?
A:
[188-268]
-----------------------------------------------------------------------------------------------------------------
K
H
T
I
V
Y
D
---
G
E
V
D
K
----
I
S
A
T
V
---------------------------
V
G
W
G
Y
N
D
G
K
I
L
---------
I
C
D
I
K
D
Y
V
P
G
----------
Q
-
T
Q
N
L
Y
V
V
--
G
G
-----
G
A
C
------
E
K
I
S
S
I
T
K
E
K
F
I
M
I
K
G
N
-
D
R
-
F
D
T
L
Y
K
A
L
D
-----
F
-------
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
32.83
17%
-56
- C9 -
1KAE
4
HISX_ECOLI
A:
[160-261]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
S
P
P
P
I
A
D
E
I
L
Y
-
A
A
Q
L
C
-
G
-
V
Q
D
V
F
N
V
--
G
G
-----
A
Q
A
I
A
A
L
A
F
G
T
-
E
S
V
P
--
K
V
D
K
I
F
G
P
G
N
A
-
F
V
T
E
A
K
R
Q
V
S
Q
RLD
G
A
A
I
D
M
--
P
A
G
P
S
------------
E
V
L
V
I
A
D
S
-----
G
A
T
P
-
D
F
V
A
-
S
D
L
L
S
Q
A
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
32.18
14%
1
- C7 -
4CU5
-
?
A:
[188-269]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
H
T
I
V
Y
D
G
-------
E
V
-
D
K
I
S
-
A
T
V
V
G
W
G
Y
N
D
G
K
I
L
I
--
C
D
I
K
----
D
Y
V
P
---
G
---
Q
T
Q
N
L
Y
V
V
G
G
G
A
C
------
E
K
I
----
S
S
IT--
K
--
E
K
F
I
----
M
I
K
G
N
D
-
R
F
D
T
L
Y
K
A
--
L
D
F
I
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
32.11
33%
-14
- C7 -
3QTG
1
KPYK_PYRAE
A:
[344-413]
----------------------------------------------------------------------------------------------------------
N
V
E
Y
Q
I
P
Q
S
P
L
L
Q
N
S
R
D
R
F
A
K
G
----
L
--
V
E
---------------------------
L
A
Q
D
L
-
G
A
N
I
L
---------
V
F
---
S
M
S
G
T
L
A
R
-
R
I
A
K
F
-
R
-
P
R
G
V
V
Y
V
--
G
T
PN
V
R
V
A
R
S
L
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------