@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu35920: (2016-07-30 )
MRNICVIGSCSMDLVVTSDKRPKAGETVLGTSFQTVPGGKGANQAVAAARLGAQVFMVGKVGDDHYGTAILNNLKANGVRTDYMEPVTHTESGTAHIVLAEGDNSIVVVKGANDDITPAYALNALEQIEKVDMVLIQQEIPEETVDEVCKYCHSHDIPIILNPAPARPLKQETIDHATYLTPNEHEASILFPELTISEALALYPAKLFITEGKQGVRYSAGSKEVLIPSFPVEPVDTTGAGDTFNAAFAVALAEGKDIEAALRFANRAASLSVCSFGAQGGMPTRNEVEELLS
Atome Classification :
(30 SA)
.........10........20.......-.30.-.......40........50........60........70........80........90......-..-100........110.......120.......130.......140.......150.......160....---.--..170.......180.......190---.....-----.---...---------200-.---.....----..---------.210.......220.--......230.......240.......250..--.----.----.-..260--.........270.......280.......290.--
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MR
N
I
C
V
IGSCS
M
D
L
V
V
TSDKRPKAGE
T
V
-LGT
S
-
F
Q
TVPGGKG
A
N
Q
A
V
A
A
A
RLG
A
Q
V
F
M
V
G
KVGDDH
Y
G
T
A
I
L
N
NLKANGVRTDYMEPVTHTESG
T
A
H
I
-
V
L
-AE-GD
N
S
I
V
V
V
KGANDDI
T
P
A
Y
A
L
N
A
L
E
Q
I
E
K
V
D
M
V
L
I
Q
Q
EI
P
E
E
T
V
D
E
V
C
K
Y
C
HSHDI
P
I
I
LNPAPA---R--PL
K
Q
ETIDHATYLTPNEHEA
S
I
L-----FPE
L
T
-----
I
---
S
E
A
---------
L
---
A
---LY
P
A
K
----
L
F
---------
I
TEGKQG
V
R
YSAGSK--
E
V
L
IPSFPVEPVDTTGAGDTFN
A
A
F
A
V
A
LAE--G----
K
----
D
-
I
E
A
----
A
L
R
F
A
N
RAAS
L
S
V
C
SFGAQGGMP
T
R
N
E
V
E
E
L
LS--
24
PsiBlast_CBE
79.50
37%
-35
- C1 -
4XCK
2
?
D:
[4-306]
M
N
K
L
V
V
L
G
S
V
N
A
D
H
V
L
Q
V
P
S
F
P
R
P
G
E
T
L
-
H
G
R
N
-
Y
Q
V
I
P
G
G
K
G
A
N
Q
A
V
A
A
A
R
M
Q
A
D
V
G
F
I
A
C
V
G
D
D
S
F
G
I
N
I
R
E
S
F
K
L
D
G
I
N
T
A
G
V
K
L
Q
P
N
C
P
T
G
I
A
M
I
-
Q
V
-
S
D
S
G
E
N
S
I
C
I
S
A
E
A
N
A
K
L
T
A
A
A
I
E
P
D
L
A
A
I
R
D
A
R
Y
L
L
M
Q
L
E
T
P
L
D
G
I
L
K
A
A
Q
E
A
K
T
A
K
T
N
V
I
L
N
P
A
P
A
---
R
--
E
L
P
D
E
L
L
K
C
V
D
L
I
T
P
N
E
T
E
A
E
V
L
TGITV
Y
D
D
S
S
-----
A
---
Q
Q
A
---------
A
---
D
---
A
L
H
C
K
GIEI
V
I
---------
I
T
L
G
S
K
G
V
W
L
S
Q
N
G
R
--
G
Q
R
I
P
G
F
V
V
K
A
T
D
T
T
A
A
G
D
T
F
N
G
A
L
V
T
G
L
L
Q
--
E
----
M
----
P
-
L
E
S
----
A
I
K
F
A
H
A
A
A
A
I
S
V
T
R
F
G
A
Q
T
S
I
P
T
R
A
E
V
E
A
F
L
A
--
26
PsiBlast_CBE
79.15
37%
-37
- C1 -
4XCK
3
?
B:
[4-306]
M
N
K
L
V
V
L
G
S
V
N
A
D
H
V
L
Q
V
P
S
F
P
R
P
G
E
T
L
-
H
G
R
N
-
Y
Q
V
I
P
G
G
K
G
A
N
Q
A
V
A
A
A
R
M
Q
A
D
V
G
F
I
A
C
V
G
D
D
S
F
G
I
N
I
R
E
S
F
K
L
D
G
I
N
T
A
G
V
K
L
Q
P
N
C
P
T
G
I
A
M
I
-
Q
V
-
S
D
S
G
E
N
S
I
C
I
S
A
E
A
N
A
K
L
T
A
A
A
I
E
P
D
L
A
A
I
R
D
A
R
Y
L
L
M
Q
L
E
T
P
L
D
G
I
L
K
A
A
Q
E
A
K
T
A
K
T
N
V
I
L
N
P
A
P
A
---
R
--
E
L
P
D
E
L
L
K
C
V
D
L
I
T
P
N
E
T
E
A
E
V
L
TGITV
Y
D
D
S
S
-----
A
---
Q
Q
A
---------
A
---
D
---
A
L
H
C
K
GIEI
V
I
---------
I
T
L
G
S
K
G
V
W
L
S
Q
N
G
R
--
G
Q
R
I
P
G
F
V
V
K
A
T
D
T
T
A
A
G
D
T
F
N
G
A
L
V
T
G
L
L
Q
--
E
----
M
----
P
-
L
E
S
----
A
I
K
F
A
H
A
A
A
A
I
S
V
T
R
F
G
A
Q
T
S
I
P
T
R
A
E
V
E
A
F
L
A
--
59
HHSearch
78.84
38%
-36
- C1 -
4XDA
4
?
A:
[4-305]
M
N
K
L
V
V
L
G
S
V
N
A
D
H
V
L
Q
V
P
S
F
P
R
P
G
E
T
L
-
H
G
R
N
-
Y
Q
V
I
P
G
G
K
G
A
N
Q
A
V
A
A
A
R
M
Q
A
D
V
G
F
I
A
C
V
G
D
D
S
F
G
I
N
I
R
E
S
F
K
L
D
G
I
N
T
A
G
V
K
L
Q
P
N
C
P
T
G
I
A
M
I
-
Q
V
S
D
S
-
G
E
N
S
I
C
I
S
A
E
A
N
A
K
L
T
A
A
A
I
E
P
D
L
A
A
I
R
D
A
R
Y
L
L
M
Q
L
E
T
P
L
D
G
I
L
K
A
A
Q
E
A
K
T
A
K
T
N
V
I
L
N
P
A
P
A
---
R
--
E
L
P
D
E
L
L
K
C
V
D
L
I
T
P
N
E
T
E
A
E
V
L
-----
T
G
I
T
V
Y
D
D
S
S
A
---
Q
Q
A
---------
A
D
A
L
H
C
--
K
G
I
E
I
----
V
I
---------
I
T
L
G
S
K
G
V
W
L
S
Q
N
G
R
--
G
Q
R
I
P
G
F
V
V
K
A
T
D
T
T
A
A
G
D
T
F
N
G
A
L
V
T
G
L
L
Q
--
E
----
M
----
P
-
L
E
S
----
A
I
K
F
A
H
A
A
A
A
I
S
V
T
R
F
G
A
Q
T
S
I
P
T
R
A
E
V
E
A
F
L
---
25
PsiBlast_CBE
78.77
37%
-35
- C1 -
4XCK
3
?
C:
[4-306]
M
N
K
L
V
V
L
G
S
V
N
A
D
H
V
L
Q
V
P
S
F
P
R
P
G
E
T
L
-
H
G
R
N
-
Y
Q
V
I
P
G
G
K
G
A
N
Q
A
V
A
A
A
R
M
Q
A
D
V
G
F
I
A
C
V
G
D
D
S
F
G
I
N
I
R
E
S
F
K
L
D
G
I
N
T
A
G
V
K
L
Q
P
N
C
P
T
G
I
A
M
I
-
Q
V
-
S
D
S
G
E
N
S
I
C
I
S
A
E
A
N
A
K
L
T
A
A
A
I
E
P
D
L
A
A
I
R
D
A
R
Y
L
L
M
Q
L
E
T
P
L
D
G
I
L
K
A
A
Q
E
A
K
T
A
K
T
N
V
I
L
N
P
A
P
A
---
R
--
E
L
P
D
E
L
L
K
C
V
D
L
I
T
P
N
E
T
E
A
E
V
L
TGITV
Y
D
D
S
S
-----
A
---
Q
Q
A
---------
A
---
D
---
A
L
H
C
K
GIEI
V
I
---------
I
T
L
G
S
K
G
V
W
L
S
Q
N
G
R
--
G
Q
R
I
P
G
F
V
V
K
A
T
D
T
T
A
A
G
D
T
F
N
G
A
L
V
T
G
L
L
Q
--
E
----
M
----
P
-
L
E
S
----
A
I
K
F
A
H
A
A
A
A
I
S
V
T
R
F
G
A
Q
T
S
I
P
T
R
A
E
V
E
A
F
L
A
--
21
PsiBlast_CBE
78.67
37%
-35
- C1 -
4XDA
3
?
D:
[4-306]
M
N
K
L
V
V
L
G
S
V
N
A
D
H
V
L
Q
V
P
S
F
P
R
P
G
E
T
L
-
H
G
R
N
-
Y
Q
V
I
P
G
G
K
G
A
N
Q
A
V
A
A
A
R
M
Q
A
D
V
G
F
I
A
C
V
G
D
D
S
F
G
I
N
I
R
E
S
F
K
L
D
G
I
N
T
A
G
V
K
L
Q
P
N
C
P
T
G
I
A
M
I
-
Q
V
-
S
D
S
G
E
N
S
I
C
I
S
A
E
A
N
A
K
L
T
A
A
A
I
E
P
D
L
A
A
I
R
D
A
R
Y
L
L
M
Q
L
E
T
P
L
D
G
I
L
K
A
A
Q
E
A
K
T
A
K
T
N
V
I
L
N
P
A
P
A
---
R
--
E
L
P
D
E
L
L
K
C
V
D
L
I
T
P
N
E
T
E
A
E
V
L
TGITV
Y
D
D
S
S
-----
A
---
Q
Q
A
---------
A
---
D
---
A
L
H
C
K
GIEI
V
I
---------
I
T
L
G
S
K
G
V
W
L
S
Q
N
G
R
--
G
Q
R
I
P
G
F
V
V
K
A
T
D
T
T
A
A
G
D
T
F
N
G
A
L
V
T
G
L
L
Q
--
E
----
M
----
P
-
L
E
S
----
A
I
K
F
A
H
A
A
A
A
I
S
V
T
R
F
G
A
Q
T
S
I
P
T
R
A
E
V
E
A
F
L
A
--
3
PsiBlast_PDB
78.54
37%
-36
- C1 -
4XDA
4
?
A:
[4-306]
M
N
K
L
V
V
L
G
S
V
N
A
D
H
V
L
Q
V
P
S
F
P
R
P
G
E
T
L
-
H
G
R
N
-
Y
Q
V
I
P
G
G
K
G
A
N
Q
A
V
A
A
A
R
M
Q
A
D
V
G
F
I
A
C
V
G
D
D
S
F
G
I
N
I
R
E
S
F
K
L
D
G
I
N
T
A
G
V
K
L
Q
P
N
C
P
T
G
I
A
M
I
-
Q
V
-
S
D
S
G
E
N
S
I
C
I
S
A
E
A
N
A
K
L
T
A
A
A
I
E
P
D
L
A
A
I
R
D
A
R
Y
L
L
M
Q
L
E
T
P
L
D
G
I
L
K
A
A
Q
E
A
K
T
A
K
T
N
V
I
L
N
P
A
P
A
---
R
--
E
L
P
D
E
L
L
K
C
V
D
L
I
T
P
N
E
T
E
A
E
V
L
TG
I
T
V
Y
D
D
S
S
-----
A
---
Q
Q
A
---------
A
---
D
---
A
L
H
C
K
GIE
I
V
I
---------
I
T
L
G
S
K
G
V
W
L
S
Q
N
G
R
--
G
Q
R
I
P
G
F
V
V
K
A
T
D
T
T
A
A
G
D
T
F
N
G
A
L
V
T
G
L
L
Q
--
E
----
M
----
P
-
L
E
S
----
A
I
K
F
A
H
A
A
A
A
I
S
V
T
R
F
G
A
Q
T
S
I
P
T
R
A
E
V
E
A
F
L
A
--
22
PsiBlast_CBE
78.29
37%
-35
- C1 -
4XDA
3
?
C:
[4-306]
M
N
K
L
V
V
L
G
S
V
N
A
D
H
V
L
Q
V
P
S
F
P
R
P
G
E
T
L
-
H
G
R
N
-
Y
Q
V
I
P
G
G
K
G
A
N
Q
A
V
A
A
A
R
M
Q
A
D
V
G
F
I
A
C
V
G
D
D
S
F
G
I
N
I
R
E
S
F
K
L
D
G
I
N
T
A
G
V
K
L
Q
P
N
C
P
T
G
I
A
M
I
-
Q
V
-
S
D
S
G
E
N
S
I
C
I
S
A
E
A
N
A
K
L
T
A
A
A
I
E
P
D
L
A
A
I
R
D
A
R
Y
L
L
M
Q
L
E
T
P
L
D
G
I
L
K
A
A
Q
E
A
K
T
A
K
T
N
V
I
L
N
P
A
P
A
---
R
--
E
L
P
D
E
L
L
K
C
V
D
L
I
T
P
N
E
T
E
A
E
V
L
TGITV
Y
D
D
S
S
-----
A
---
Q
Q
A
---------
A
---
D
---
A
L
H
C
K
GIEI
V
I
---------
I
T
L
G
S
K
G
V
W
L
S
Q
N
G
R
--
G
Q
R
I
P
G
F
V
V
K
A
T
D
T
T
A
A
G
D
T
F
N
G
A
L
V
T
G
L
L
Q
--
E
----
M
----
P
-
L
E
S
----
A
I
K
F
A
H
A
A
A
A
I
S
V
T
R
F
G
A
Q
T
S
I
P
T
R
A
E
V
E
A
F
L
A
--
2
PsiBlast_PDB
77.96
37%
-35
- C1 -
4XCK
4
?
A:
[4-306]
M
N
K
L
V
V
L
G
S
V
N
A
D
H
V
L
Q
V
P
S
F
P
R
P
G
E
T
L
-
H
G
R
N
-
Y
Q
V
I
P
G
G
K
G
A
N
Q
A
V
A
A
A
R
M
Q
A
D
V
G
F
I
A
C
V
G
D
D
S
F
G
I
N
I
R
E
S
F
K
L
D
G
I
N
T
A
G
V
K
L
Q
P
N
C
P
T
G
I
A
M
I
-
Q
V
-
S
D
S
G
E
N
S
I
C
I
S
A
E
A
N
A
K
L
T
A
A
A
I
E
P
D
L
A
A
I
R
D
A
R
Y
L
L
M
Q
L
E
T
P
L
D
G
I
L
K
A
A
Q
E
A
K
T
A
K
T
N
V
I
L
N
P
A
P
A
---
R
--
E
L
P
D
E
L
L
K
C
V
D
L
I
T
P
N
E
T
E
A
E
V
L
TGITV
Y
D
D
S
S
-----
A
---
Q
Q
A
---------
A
---
D
---
A
L
H
C
K
GIE
I
V
I
---------
I
T
L
G
S
K
G
V
W
L
S
Q
N
G
R
--
G
Q
R
I
P
G
F
V
V
K
A
T
D
T
T
A
A
G
D
T
F
N
G
A
L
V
T
G
L
L
Q
--
E
----
M
----
P
-
L
E
S
----
A
I
K
F
A
H
A
A
A
A
I
S
V
T
R
F
G
A
Q
T
S
I
P
T
R
A
E
V
E
A
F
L
A
--
1
PsiBlast_PDB
77.91
37%
-33
* C1 *
4X8F
-
?
A:
[1-303]
M
N
K
L
V
V
L
G
S
V
N
A
D
H
V
L
Q
V
P
S
F
P
R
P
G
E
T
L
-
H
G
R
N
-
Y
Q
V
I
P
G
G
K
G
A
N
Q
A
V
A
A
A
R
M
Q
A
D
V
G
F
I
A
C
V
G
D
D
S
F
G
I
N
I
R
E
S
F
K
L
D
G
I
N
T
A
G
V
K
L
Q
P
N
C
P
T
G
I
A
M
I
-
Q
V
-
S
D
S
G
E
N
S
I
C
I
S
A
E
A
N
A
K
L
T
A
A
A
I
E
P
D
L
A
A
I
R
D
A
R
Y
L
L
M
Q
L
E
T
P
L
D
G
I
L
K
A
A
Q
E
A
K
T
A
K
T
N
V
I
L
N
P
A
P
A
---
R
--
E
L
P
D
E
L
L
K
C
V
D
L
I
T
P
N
E
T
E
A
E
V
L
TGITV
Y
D
D
S
S
-----
A
---
Q
Q
A
---------
A
---
D
---
A
L
H
C
K
GIE
I
V
I
---------
I
T
L
G
S
K
G
V
W
L
S
Q
N
G
R
--
G
Q
R
I
P
G
F
V
V
K
A
T
D
T
T
A
A
G
D
T
F
N
G
A
L
V
T
G
L
L
Q
--
E
----
M
----
P
-
L
E
S
----
A
I
K
F
A
H
A
A
A
A
I
S
V
T
R
F
G
A
Q
T
S
I
P
T
R
A
E
V
E
A
F
L
A
--
23
PsiBlast_CBE
77.85
37%
-36
- C1 -
4XDA
3
?
B:
[4-306]
M
N
K
L
V
V
L
G
S
V
N
A
D
H
V
L
Q
V
P
S
F
P
R
P
G
E
T
L
-
H
G
R
N
-
Y
Q
V
I
P
G
G
K
G
A
N
Q
A
V
A
A
A
R
M
Q
A
D
V
G
F
I
A
C
V
G
D
D
S
F
G
I
N
I
R
E
S
F
K
L
D
G
I
N
T
A
G
V
K
L
Q
P
N
C
P
T
G
I
A
M
I
-
Q
V
-
S
D
S
G
E
N
S
I
C
I
S
A
E
A
N
A
K
L
T
A
A
A
I
E
P
D
L
A
A
I
R
D
A
R
Y
L
L
M
Q
L
E
T
P
L
D
G
I
L
K
A
A
Q
E
A
K
T
A
K
T
N
V
I
L
N
P
A
P
A
---
R
--
E
L
P
D
E
L
L
K
C
V
D
L
I
T
P
N
E
T
E
A
E
V
L
TGITV
Y
D
D
S
S
-----
A
---
Q
Q
A
---------
A
---
D
---
A
L
H
C
K
GIEI
V
I
---------
I
T
L
G
S
K
G
V
W
L
S
Q
N
G
R
--
G
Q
R
I
P
G
F
V
V
K
A
T
D
T
T
A
A
G
D
T
F
N
G
A
L
V
T
G
L
L
Q
--
E
----
M
----
P
-
L
E
S
----
A
I
K
F
A
H
A
A
A
A
I
S
V
T
R
F
G
A
Q
T
S
I
P
T
R
A
E
V
E
A
F
L
A
--
30
PsiBlast_CBE
75.00
36%
-35
- C1 -
1GQT
3
RBSK_ECOLI
D:
[6-305]
--
S
L
V
V
L
G
S
I
N
A
D
H
I
L
N
L
Q
S
F
P
T
P
G
E
T
V
-
T
G
N
H
-
Y
Q
V
A
F
G
G
K
G
A
N
Q
A
V
A
A
G
R
S
G
A
N
I
A
F
I
A
C
T
G
D
D
S
I
G
E
S
V
R
Q
Q
L
A
T
D
N
I
D
I
T
P
V
S
V
I
K
G
E
S
T
G
V
A
L
I
F
V
N
-
G
E
-
G
E
N
V
I
G
I
H
A
G
A
N
A
A
L
S
P
A
L
V
E
A
Q
R
E
R
I
A
N
A
S
A
L
L
M
Q
L
E
S
P
L
E
S
V
M
A
A
A
K
I
A
H
Q
N
K
T
I
V
A
L
N
P
A
P
A
---
R
--
E
L
P
D
E
L
L
A
L
V
D
I
I
T
P
N
E
T
E
A
E
K
L
-----
T
G
I
R
V
-----
E
---
N
D
E
---------
D
---
A
---
A
K
A
A
Q
----
V
L
HEKGIRTVL
I
T
L
G
S
R
G
V
W
A
S
V
N
G
E
--
G
Q
R
V
P
G
F
R
V
Q
A
V
D
T
I
A
A
G
D
T
F
N
G
A
L
I
T
A
L
L
E
--
E
----
K
----
P
-
L
P
E
----
A
I
R
F
A
H
A
A
A
A
I
A
V
T
R
K
G
A
Q
P
S
V
P
W
R
E
E
I
D
A
F
L
---
31
PsiBlast_CBE
74.48
36%
-32
- C1 -
1GQT
3
RBSK_ECOLI
C:
[6-305]
--
S
L
V
V
L
G
S
I
N
A
D
H
I
L
N
L
Q
S
F
P
T
P
G
E
T
V
-
T
G
N
H
-
Y
Q
V
A
F
G
G
K
G
A
N
Q
A
V
A
A
G
R
S
G
A
N
I
A
F
I
A
C
T
G
D
D
S
I
G
E
S
V
R
Q
Q
L
A
T
D
N
I
D
I
T
P
V
S
V
I
K
G
E
S
T
G
V
A
L
I
F
V
N
-
G
E
-
G
E
N
V
I
G
I
H
A
G
A
N
A
A
L
S
P
A
L
V
E
A
Q
R
E
R
I
A
N
A
S
A
L
L
M
Q
L
E
S
P
L
E
S
V
M
A
A
A
K
I
A
H
Q
N
K
T
I
V
A
L
N
P
A
P
A
---
R
--
E
L
P
D
E
L
L
A
L
V
D
I
I
T
P
N
E
T
E
A
E
K
L
-----
T
G
I
R
V
-----
E
---
N
D
E
---------
D
---
A
---
A
K
A
A
Q
----
V
L
HEKGIRTVL
I
T
L
G
S
R
G
V
W
A
S
V
N
G
E
--
G
Q
R
V
P
G
F
R
V
Q
A
V
D
T
I
A
A
G
D
T
F
N
G
A
L
I
T
A
L
L
E
--
E
----
K
----
P
-
L
P
E
----
A
I
R
F
A
H
A
A
A
A
I
A
V
T
R
K
G
A
Q
P
S
V
P
W
R
E
E
I
D
A
F
L
---
60
HHSearch
74.09
36%
-33
- C1 -
1RKD
4
RBSK_ECOLI
A:
[4-305]
A
G
S
L
V
V
L
G
S
I
N
A
D
H
I
L
N
L
Q
S
F
P
T
P
G
E
T
V
-
T
G
N
H
-
Y
Q
V
A
F
G
G
K
G
A
N
Q
A
V
A
A
G
R
S
G
A
N
I
A
F
I
A
C
T
G
D
D
S
I
G
E
S
V
R
Q
Q
L
A
T
D
N
I
D
I
T
P
V
S
V
I
K
G
E
S
T
G
V
A
L
I
-
F
V
N
G
E
-
G
E
N
V
I
G
I
H
A
G
A
N
A
A
L
S
P
A
L
V
E
A
Q
R
E
R
I
A
N
A
S
A
L
L
M
Q
L
E
S
P
L
E
S
V
M
A
A
A
K
I
A
H
Q
N
K
T
I
V
A
L
N
P
A
P
A
---
R
--
E
L
P
D
E
L
L
A
L
V
D
I
I
T
P
N
E
T
E
A
E
K
L
-----
T
G
I
R
V
EN---
D
E
D
A
A
K
A
---------
A
Q
V
L
H
E
--
K
G
I
R
T
----
V
L
---------
I
T
L
G
S
R
G
V
W
A
S
V
N
G
E
--
G
Q
R
V
P
G
F
R
V
Q
A
V
D
T
I
A
A
G
D
T
F
N
G
A
L
I
T
A
L
L
E
--
E
----
K
----
P
-
L
P
E
----
A
I
R
F
A
H
A
A
A
A
I
A
V
T
R
K
G
A
Q
P
S
V
P
W
R
E
E
I
D
A
F
L
---
7
PsiBlast_PDB
74.09
36%
-28
- C1 -
1RKA
-
RBSK_ECOLI
A:
[6-305]
--
S
L
V
V
L
G
S
I
N
A
D
H
I
L
N
L
Q
S
F
P
T
P
G
E
T
V
-
T
G
N
H
-
Y
Q
V
A
F
G
G
K
G
A
N
Q
A
V
A
A
G
R
S
G
A
N
I
A
F
I
A
C
T
G
D
D
S
I
G
E
S
V
R
Q
Q
L
A
T
D
N
I
D
I
T
P
V
S
V
I
K
G
E
S
T
G
V
A
L
I
F
V
N
-
G
E
-
G
E
N
V
I
G
I
H
A
G
A
N
A
A
L
S
P
A
L
V
E
A
Q
R
E
R
I
A
N
A
S
A
L
L
M
Q
L
E
S
P
L
E
S
V
M
A
A
A
K
I
A
H
Q
N
K
T
I
V
A
L
N
P
A
P
A
---
R
--
E
L
P
D
E
L
L
A
L
V
D
I
I
T
P
N
E
T
E
A
E
K
L
-----
T
G
I
R
V
-----
E
---
N
D
E
---------
D
---
A
---
A
K
A
A
Q
----
V
L
H
E
K
GIR
T
V
L
I
T
L
G
S
R
G
V
W
A
S
V
N
G
E
--
G
Q
R
V
P
G
F
R
V
Q
A
V
D
T
I
A
A
G
D
T
F
N
G
A
L
I
T
A
L
L
E
--
E
----
K
----
P
-
L
P
E
----
A
I
R
F
A
H
A
A
A
A
I
A
V
T
R
K
G
A
Q
P
S
V
P
W
R
E
E
I
D
A
F
L
---
32
PsiBlast_CBE
73.60
36%
-32
- C1 -
1GQT
3
RBSK_ECOLI
B:
[6-305]
--
S
L
V
V
L
G
S
I
N
A
D
H
I
L
N
L
Q
S
F
P
T
P
G
E
T
V
-
T
G
N
H
-
Y
Q
V
A
F
G
G
K
G
A
N
Q
A
V
A
A
G
R
S
G
A
N
I
A
F
I
A
C
T
G
D
D
S
I
G
E
S
V
R
Q
Q
L
A
T
D
N
I
D
I
T
P
V
S
V
I
K
G
E
S
T
G
V
A
L
I
F
V
N
-
G
E
-
G
E
N
V
I
G
I
H
A
G
A
N
A
A
L
S
P
A
L
V
E
A
Q
R
E
R
I
A
N
A
S
A
L
L
M
Q
L
E
S
P
L
E
S
V
M
A
A
A
K
I
A
H
Q
N
K
T
I
V
A
L
N
P
A
P
A
---
R
--
E
L
P
D
E
L
L
A
L
V
D
I
I
T
P
N
E
T
E
A
E
K
L
-----
T
G
I
R
V
-----
E
---
N
D
E
---------
D
---
A
---
A
K
A
A
Q
----
V
L
H
E
K
GIR
T
V
L
I
T
L
G
S
R
G
V
W
A
S
V
N
G
E
--
G
Q
R
V
P
G
F
R
V
Q
A
V
D
T
I
A
A
G
D
T
F
N
G
A
L
I
T
A
L
L
E
--
E
----
K
----
P
-
L
P
E
----
A
I
R
F
A
H
A
A
A
A
I
A
V
T
R
K
G
A
Q
P
S
V
P
W
R
E
E
I
D
A
F
L
---
8
PsiBlast_PDB
73.57
36%
-32
- C1 -
1RKS
3
RBSK_ECOLI
A:
[6-305]
--
S
L
V
V
L
G
S
I
N
A
D
H
I
L
N
L
Q
S
F
P
T
P
G
E
T
V
-
T
G
N
H
-
Y
Q
V
A
F
G
G
K
G
A
N
Q
A
V
A
A
G
R
S
G
A
N
I
A
F
I
A
C
T
G
D
D
S
I
G
E
S
V
R
Q
Q
L
A
T
D
N
I
D
I
T
P
V
S
V
I
K
G
E
S
T
G
V
A
L
I
F
V
N
-
G
E
-
G
E
N
V
I
G
I
H
A
G
A
N
A
A
L
S
P
A
L
V
E
A
Q
R
E
R
I
A
N
A
S
A
L
L
M
Q
L
E
S
P
L
E
S
V
M
A
A
A
K
I
A
H
Q
N
K
T
I
V
A
L
N
P
A
P
A
---
R
--
E
L
P
D
E
L
L
A
L
V
D
I
I
T
P
N
E
T
E
A
E
K
L
-----
T
G
I
R
V
-----
E
---
N
D
E
---------
D
---
A
---
A
K
A
A
Q
----
V
L
H
E
K
GIR
T
V
L
I
T
L
G
S
R
G
V
W
A
S
V
N
G
E
--
G
Q
R
V
P
G
F
R
V
Q
A
V
D
T
I
A
A
G
D
T
F
N
G
A
L
I
T
A
L
L
E
--
E
----
K
----
P
-
L
P
E
----
A
I
R
F
A
H
A
A
A
A
I
A
V
T
R
K
G
A
Q
P
S
V
P
W
R
E
E
I
D
A
F
L
---
62
HHSearch
73.26
36%
-33
- C1 -
2FV7
8
RBSK_HUMAN
A:
[24-330]
V
A
A
V
V
V
V
G
S
C
M
T
D
L
V
S
L
T
S
R
L
P
K
T
G
E
T
I
-
H
G
H
K
-
F
F
I
G
F
G
G
K
G
A
N
Q
C
V
Q
A
A
R
L
G
A
M
T
S
M
V
C
K
V
G
K
D
S
F
G
N
D
Y
I
E
N
L
K
Q
N
D
I
S
T
E
F
T
Y
Q
T
K
D
A
A
T
G
T
A
S
I
-
I
V
N
N
E
-
G
Q
N
I
I
V
I
V
A
G
A
N
L
L
L
N
T
E
D
L
R
A
A
A
N
V
I
S
R
A
K
V
M
V
C
Q
L
E
I
T
P
A
T
S
L
E
A
L
T
M
A
R
R
S
G
V
K
T
L
F
N
P
A
P
A
I--
A
--
D
L
D
P
Q
F
Y
T
L
S
D
V
F
C
C
N
E
S
E
A
E
I
L
-----
T
G
L
T
V
GS
A
A
D
A
---
G
E
A
---------
A
L
--
V
L
L
K
R
G
C
Q
V
----
V
I
---------
I
T
L
G
A
E
G
C
V
V
L
S
Q
T
E
P
E
P
K
H
I
P
T
E
K
V
K
A
V
D
T
T
G
A
G
D
S
F
V
G
A
L
A
F
Y
L
A
Y
YP
N
----
L
----
S
-
L
E
D
----
M
L
N
R
S
N
F
I
A
A
V
S
V
Q
A
A
G
T
Q
S
S
Y
P
Y
K
K
D
L
P
L
T
L
---
10
PsiBlast_PDB
73.08
36%
-31
- C1 -
1RKD
4
RBSK_ECOLI
A:
[6-305]
--
S
L
V
V
L
G
S
I
N
A
D
H
I
L
N
L
Q
S
F
P
T
P
G
E
T
V
-
T
G
N
H
-
Y
Q
V
A
F
G
G
K
G
A
N
Q
A
V
A
A
G
R
S
G
A
N
I
A
F
I
A
C
T
G
D
D
S
I
G
E
S
V
R
Q
Q
L
A
T
D
N
I
D
I
T
P
V
S
V
I
K
G
E
S
T
G
V
A
L
I
F
V
N
-
G
E
-
G
E
N
V
I
G
I
H
A
G
A
N
A
A
L
S
P
A
L
V
E
A
Q
R
E
R
I
A
N
A
S
A
L
L
M
Q
L
E
S
P
L
E
S
V
M
A
A
A
K
I
A
H
Q
N
K
T
I
V
A
L
N
P
A
P
A
---
R
--
E
L
P
D
E
L
L
A
L
V
D
I
I
T
P
N
E
T
E
A
E
K
L
-----
T
G
I
R
V
-----
E
---
N
D
E
---------
D
---
A
---
A
K
A
A
Q
----
V
L
H
E
K
GIR
T
V
L
I
T
L
G
S
R
G
V
W
A
S
V
N
G
E
--
G
Q
R
V
P
G
F
R
V
Q
A
V
D
T
I
A
A
G
D
T
F
N
G
A
L
I
T
A
L
L
E
--
E
----
K
----
P
-
L
P
E
----
A
I
R
F
A
H
A
A
A
A
I
A
V
T
R
K
G
A
Q
P
S
V
P
W
R
E
E
I
D
A
F
L
---
28
PsiBlast_CBE
72.99
36%
-24
- C1 -
1RK2
4
RBSK_ECOLI
C:
[6-305]
--
S
L
V
V
L
G
S
I
N
A
D
H
I
L
N
L
Q
S
F
P
T
P
G
E
T
V
-
T
G
N
H
-
Y
Q
V
A
F
G
G
K
G
A
N
Q
A
V
A
A
G
R
S
G
A
N
I
A
F
I
A
C
T
G
D
D
S
I
G
E
S
V
R
Q
Q
L
A
T
D
N
I
D
I
T
P
V
S
V
I
K
G
E
S
T
G
V
A
L
I
F
V
N
-
G
E
-
G
E
N
V
I
G
I
H
A
G
A
N
A
A
L
S
P
A
L
V
E
A
Q
R
E
R
I
A
N
A
S
A
L
L
M
Q
L
E
S
P
L
E
S
V
M
A
A
A
K
I
A
H
Q
N
K
T
I
V
A
L
N
P
A
P
A
---
R
--
E
L
P
D
E
L
L
A
L
V
D
I
I
T
P
N
E
T
E
A
E
K
L
-----
T
G
I
R
V
-----
E
---
N
D
E
---------
D
---
A
---
A
K
A
A
Q
----
V
L
HEKGIRTVL
I
T
L
G
S
R
G
V
W
A
S
V
N
G
E
--
G
Q
R
V
P
G
F
R
V
Q
A
V
D
T
I
A
A
G
D
T
F
N
G
A
L
I
T
A
L
L
E
--
E
----
K
----
P
-
L
P
E
----
A
I
R
F
A
H
A
A
A
A
I
A
V
T
R
K
G
A
Q
P
S
V
P
W
R
E
E
I
D
A
F
L
---
6
PsiBlast_PDB
72.47
36%
-24
- C1 -
1RK2
4
RBSK_ECOLI
A:
[6-305]
--
S
L
V
V
L
G
S
I
N
A
D
H
I
L
N
L
Q
S
F
P
T
P
G
E
T
V
-
T
G
N
H
-
Y
Q
V
A
F
G
G
K
G
A
N
Q
A
V
A
A
G
R
S
G
A
N
I
A
F
I
A
C
T
G
D
D
S
I
G
E
S
V
R
Q
Q
L
A
T
D
N
I
D
I
T
P
V
S
V
I
K
G
E
S
T
G
V
A
L
I
F
V
N
-
G
E
-
G
E
N
V
I
G
I
H
A
G
A
N
A
A
L
S
P
A
L
V
E
A
Q
R
E
R
I
A
N
A
S
A
L
L
M
Q
L
E
S
P
L
E
S
V
M
A
A
A
K
I
A
H
Q
N
K
T
I
V
A
L
N
P
A
P
A
---
R
--
E
L
P
D
E
L
L
A
L
V
D
I
I
T
P
N
E
T
E
A
E
K
L
-----
T
G
I
R
V
-----
E
---
N
D
E
---------
D
---
A
---
A
K
A
A
Q
----
V
L
H
E
K
GIR
T
V
L
I
T
L
G
S
R
G
V
W
A
S
V
N
G
E
--
G
Q
R
V
P
G
F
R
V
Q
A
V
D
T
I
A
A
G
D
T
F
N
G
A
L
I
T
A
L
L
E
--
E
----
K
----
P
-
L
P
E
----
A
I
R
F
A
H
A
A
A
A
I
A
V
T
R
K
G
A
Q
P
S
V
P
W
R
E
E
I
D
A
F
L
---
9
PsiBlast_PDB
72.27
36%
-30
- C1 -
1GQT
3
RBSK_ECOLI
A:
[6-305]
--
S
L
V
V
L
G
S
I
N
A
D
H
I
L
N
L
Q
S
F
P
T
P
G
E
T
V
-
T
G
N
H
-
Y
Q
V
A
F
G
G
K
G
A
N
Q
A
V
A
A
G
R
S
G
A
N
I
A
F
I
A
C
T
G
D
D
S
I
G
E
S
V
R
Q
Q
L
A
T
D
N
I
D
I
T
P
V
S
V
I
K
G
E
S
T
G
V
A
L
I
F
V
N
-
G
E
-
G
E
N
V
I
G
I
H
A
G
A
N
A
A
L
S
P
A
L
V
E
A
Q
R
E
R
I
A
N
A
S
A
L
L
M
Q
L
E
S
P
L
E
S
V
M
A
A
A
K
I
A
H
Q
N
K
T
I
V
A
L
N
P
A
P
A
---
R
--
E
L
P
D
E
L
L
A
L
V
D
I
I
T
P
N
E
T
E
A
E
K
L
-----
T
G
I
R
V
-----
E
---
N
D
E
---------
D
---
A
---
A
K
A
A
Q
----
V
L
H
E
K
GIR
T
V
L
I
T
L
G
S
R
G
V
W
A
S
V
N
G
E
--
G
Q
R
V
P
G
F
R
V
Q
A
V
D
T
I
A
A
G
D
T
F
N
G
A
L
I
T
A
L
L
E
--
E
----
K
----
P
-
L
P
E
----
A
I
R
F
A
H
A
A
A
A
I
A
V
T
R
K
G
A
Q
P
S
V
P
W
R
E
E
I
D
A
F
L
---
29
PsiBlast_CBE
72.23
36%
-23
- C1 -
1RK2
5
RBSK_ECOLI
B:
[6-305]
--
S
L
V
V
L
G
S
I
N
A
D
H
I
L
N
L
Q
S
F
P
T
P
G
E
T
V
-
T
G
N
H
-
Y
Q
V
A
F
G
G
K
G
A
N
Q
A
V
A
A
G
R
S
G
A
N
I
A
F
I
A
C
T
G
D
D
S
I
G
E
S
V
R
Q
Q
L
A
T
D
N
I
D
I
T
P
V
S
V
I
K
G
E
S
T
G
V
A
L
I
F
V
N
-
G
E
-
G
E
N
V
I
G
I
H
A
G
A
N
A
A
L
S
P
A
L
V
E
A
Q
R
E
R
I
A
N
A
S
A
L
L
M
Q
L
E
S
P
L
E
S
V
M
A
A
A
K
I
A
H
Q
N
K
T
I
V
A
L
N
P
A
P
A
---
R
--
E
L
P
D
E
L
L
A
L
V
D
I
I
T
P
N
E
T
E
A
E
K
L
-----
T
G
I
R
V
-----
E
---
N
D
E
---------
D
---
A
---
A
K
A
A
Q
----
V
L
H
E
K
GIR
T
V
L
I
T
L
G
S
R
G
V
W
A
S
V
N
G
E
--
G
Q
R
V
P
G
F
R
V
Q
A
V
D
T
I
A
A
G
D
T
F
N
G
A
L
I
T
A
L
L
E
--
E
----
K
----
P
-
L
P
E
----
A
I
R
F
A
H
A
A
A
A
I
A
V
T
R
K
G
A
Q
P
S
V
P
W
R
E
E
I
D
A
F
L
---
27
PsiBlast_CBE
72.13
36%
-24
- C1 -
1RK2
5
RBSK_ECOLI
D:
[6-305]
--
S
L
V
V
L
G
S
I
N
A
D
H
I
L
N
L
Q
S
F
P
T
P
G
E
T
V
-
T
G
N
H
-
Y
Q
V
A
F
G
G
K
G
A
N
Q
A
V
A
A
G
R
S
G
A
N
I
A
F
I
A
C
T
G
D
D
S
I
G
E
S
V
R
Q
Q
L
A
T
D
N
I
D
I
T
P
V
S
V
I
K
G
E
S
T
G
V
A
L
I
F
V
N
-
G
E
-
G
E
N
V
I
G
I
H
A
G
A
N
A
A
L
S
P
A
L
V
E
A
Q
R
E
R
I
A
N
A
S
A
L
L
M
Q
L
E
S
P
L
E
S
V
M
A
A
A
K
I
A
H
Q
N
K
T
I
V
A
L
N
P
A
P
A
---
R
--
E
L
P
D
E
L
L
A
L
V
D
I
I
T
P
N
E
T
E
A
E
K
L
-----
T
G
I
R
V
-----
E
---
N
D
E
---------
D
---
A
---
A
K
A
A
Q
----
V
L
HEKGIRTVL
I
T
L
G
S
R
G
V
W
A
S
V
N
G
E
--
G
Q
R
V
P
G
F
R
V
Q
A
V
D
T
I
A
A
G
D
T
F
N
G
A
L
I
T
A
L
L
E
--
E
----
K
----
P
-
L
P
E
----
A
I
R
F
A
H
A
A
A
A
I
A
V
T
R
K
G
A
Q
P
S
V
P
W
R
E
E
I
D
A
F
L
---
64
HHSearch
71.94
38%
-20
- C1 -
3GO6
2
?
A:
[19-303]
A
P
R
V
C
V
V
G
S
V
N
M
D
L
T
F
V
V
D
A
L
P
R
P
G
E
T
V
-
L
A
A
S
-
L
T
R
T
P
G
G
K
G
A
N
Q
A
V
A
A
A
R
A
G
A
Q
V
Q
F
S
G
A
F
G
D
D
P
A
A
A
Q
L
R
A
H
L
R
A
N
A
V
G
L
D
R
T
V
T
V
P
-
G
P
S
G
T
A
I
I
-
V
V
D
A
S
-
A
E
N
T
V
L
V
A
P
G
A
N
A
H
L
T
P
V
P
-----
S
A
V
A
N
C
D
V
L
L
T
Q
L
E
I
P
V
A
T
A
L
A
A
A
R
A
A
Q
S
A
D
A
V
V
M
V
N
A
S
P
A
G--
Q
D
R
S
S
L
Q
D
L
A
A
I
A
D
V
V
I
A
N
E
H
E
A
N
D
W
-----
P
S
---------------------------------
P
P
T
H
----
F
V
---------
I
T
L
G
V
R
G
A
R
Y
V
G
A
D
G
--
V
F
E
V
P
A
P
T
V
T
P
V
D
T
A
G
A
G
D
V
F
A
G
V
L
A
A
N
W
P
R
--
N
----
P
GS
P
A
E
-
R
L
R
----
A
L
R
R
A
C
A
A
G
A
L
A
T
L
V
S
G
V
G
D
C
A
P
A
A
A
A
I
D
A
A
L
R
--
52
Fugue
70.31
37%
-21
- C1 -
3GO6
2
?
A:
[19-305]
A
P
R
V
C
V
V
G
S
V
N
M
D
L
T
F
V
V
D
A
L
P
R
P
G
E
T
V
-
L
A
A
S
-
L
T
R
T
P
G
G
K
G
A
N
Q
A
V
A
A
A
R
A
G
A
Q
V
Q
F
S
G
A
F
G
D
D
P
A
A
A
Q
L
R
A
H
L
R
A
N
A
V
G
L
D
R
T
V
T
V
P
G
-
P
S
G
T
A
I
I
-
V
V
D
A
S
-
A
E
N
T
V
L
V
A
P
G
A
N
A
H
L
T
P
V
P
-----
S
A
V
A
N
C
D
V
L
L
T
Q
L
E
I
P
V
A
T
A
L
A
A
A
R
A
A
Q
S
A
D
A
V
V
M
V
N
A
S
P
A
GQD
R
--
S
S
L
Q
D
L
A
A
I
A
D
V
V
I
A
N
E
H
E
A
N
D
W
-----
P
S
P
P
T
---------------------------------
H
----
F
V
---------
I
T
L
G
V
R
G
A
R
Y
V
G
A
D
G
--
V
F
E
V
P
A
P
T
V
T
P
V
D
T
A
G
A
G
D
V
F
A
G
V
L
A
A
N
W
P
R
--
N
PGS
P
A
----
E
-
R
L
R
----
A
L
R
R
A
C
A
A
G
A
L
A
T
L
V
S
G
V
G
D
C
A
P
A
A
A
A
I
D
A
A
L
R
A
N
35
PsiBlast_CBE
68.55
37%
-40
- C1 -
3GO6
2
?
B:
[22-287]
---
V
C
V
V
G
S
V
N
M
D
L
T
F
V
V
D
A
L
P
R
P
G
E
T
V
-
L
A
A
S
-
L
T
R
T
P
G
G
K
G
A
N
Q
A
V
A
A
A
R
A
G
A
Q
V
Q
F
S
G
A
F
G
D
D
P
A
A
A
Q
L
R
A
H
L
R
A
N
A
V
G
L
D
R
T
V
T
V
P
G
-
P
S
G
T
A
I
I
-
V
V
D
A
S
-
A
E
N
T
V
L
V
A
P
G
A
N
A
H
L
T
P
V
P
S
-----
A
V
A
N
C
D
V
L
L
T
Q
L
E
I
P
V
A
T
A
L
A
A
A
R
A
A
Q
S
A
D
A
V
V
M
V
N
A
S
P
A
GQD
R
--
S
S
L
Q
D
L
A
A
I
A
D
V
V
I
A
N
E
H
E
A
N
D
------
W
P
S
--------------------------------
P
P
T
H
----
F
V
---------
I
T
L
G
V
R
G
A
R
Y
V
G
A
D
G
--
V
F
E
V
P
A
P
T
V
T
P
V
D
T
A
G
A
G
D
V
F
A
G
V
L
A
A
N
W
P
R
--
N
----
P
----
G
-
S
P
A
ERLR
A
L
R
R
A
C
A
A
G
A
L
A
T
L
V
S
G
------------------
12
PsiBlast_PDB
66.35
37%
-33
- C1 -
3GO6
2
?
A:
[22-287]
---
V
C
V
V
G
S
V
N
M
D
L
T
F
V
V
D
A
L
P
R
P
G
E
T
V
-
L
A
A
S
-
L
T
R
T
P
G
G
K
G
A
N
Q
A
V
A
A
A
R
A
G
A
Q
V
Q
F
S
G
A
F
G
D
D
P
A
A
A
Q
L
R
A
H
L
R
A
N
A
V
G
L
D
R
T
V
T
V
P
G
-
P
S
G
T
A
I
I
-
V
V
D
A
S
-
A
E
N
T
V
L
V
A
P
G
A
N
A
H
L
T
P
V
P
S
-----
A
V
A
N
C
D
V
L
L
T
Q
L
E
I
P
V
A
T
A
L
A
A
A
R
A
A
Q
S
A
D
A
V
V
M
V
N
A
S
P
A
GQD
R
--
S
S
L
Q
D
L
A
A
I
A
D
V
V
I
A
N
E
H
E
A
N
D
------
W
P
S
--------------------------------
P
P
T
H
----
F
V
---------
I
T
L
G
V
R
G
A
R
Y
V
G
A
D
G
--
V
F
E
V
P
A
P
T
V
T
P
V
D
T
A
G
A
G
D
V
F
A
G
V
L
A
A
N
W
P
R
--
N
----
P
----
G
-
S
P
A
E
R
L
R
A
L
R
R
A
C
A
A
G
A
L
A
T
L
V
S
G
------------------
13
PsiBlast_PDB
65.94
37%
-34
- C1 -
3GO7
2
?
A:
[22-287]
---
V
C
V
V
G
S
V
N
M
D
L
T
F
V
V
D
A
L
P
R
P
G
E
T
V
-
L
A
A
S
-
L
T
R
T
P
G
G
K
G
A
N
Q
A
V
A
A
A
R
A
G
A
Q
V
Q
F
S
G
A
F
G
D
D
P
A
A
A
Q
L
R
A
H
L
R
A
N
A
V
G
L
D
R
T
V
T
V
P
G
-
P
S
G
T
A
I
I
-
V
V
D
A
S
-
A
E
N
T
V
L
V
A
P
G
A
N
A
H
L
T
P
V
P
S
-----
A
V
A
N
C
D
V
L
L
T
Q
L
E
I
P
V
A
T
A
L
A
A
A
R
A
A
Q
S
A
D
A
V
V
M
V
N
A
S
P
A
GQD
R
--
S
S
L
Q
D
L
A
A
I
A
D
V
V
I
A
N
E
H
E
A
N
D
------
W
P
S
--------------------------------
P
P
T
H
----
F
V
---------
I
T
L
G
V
R
G
A
R
Y
V
G
A
D
G
--
V
F
E
V
P
A
P
T
V
T
P
V
D
T
A
G
A
G
D
V
F
A
G
V
L
A
A
N
W
P
R
--
N
----
P
----
G
-
S
P
A
E
R
L
R
A
L
R
R
A
C
A
A
G
A
L
A
T
L
V
S
G
------------------
61
HHSearch
63.17
33%
21
- C1 -
3RY7
2
?
A:
[2-303]
T
N
K
V
V
I
L
G
S
T
N
V
D
Q
F
L
T
V
E
R
Y
A
Q
P
G
E
T
L
-
H
V
E
E
A
Q
K
A
F
G
G
G
K
G
A
N
Q
A
I
A
T
A
R
M
Q
A
D
T
T
F
I
T
K
I
G
T
D
G
V
A
D
F
I
L
E
D
F
K
V
A
H
I
D
T
S
Y
I
I
K
T
A
E
A
K
T
G
Q
A
F
I
-
T
V
N
A
E
-
G
Q
N
T
I
Y
V
Y
G
G
A
N
M
T
M
T
P
E
D
V
I
N
A
K
D
A
I
I
N
A
D
F
V
V
A
Q
L
E
V
P
I
P
A
I
I
S
A
F
E
I
A
K
A
H
G
V
T
T
V
L
N
P
A
P
A
---
K
--
A
L
P
N
E
L
L
S
L
I
D
I
I
V
P
N
E
T
E
A
E
L
L
-----
S
G
I
K
V
T
N
E
Q
S
M
---
K
D
N
---------
A
N
Y
F
L
S
--
I
G
I
K
T
----
V
L
---------
I
T
L
G
K
Q
G
T
Y
F
A
T
K
N
Q
--
S
Q
H
I
E
A
Y
K
V
N
A
I
D
T
T
A
A
G
D
T
F
I
G
A
F
V
S
R
L
N
K
--
S
Q---
D
----
N
-
L
A
D
----
A
I
D
F
G
N
K
A
S
S
L
T
V
Q
K
H
G
A
Q
A
S
I
P
L
L
E
E
V
N
Q
-----
5
PsiBlast_PDB
62.05
33%
21
- C1 -
3RY7
2
?
A:
[5-304]
---
V
V
I
L
G
S
T
N
V
D
Q
F
L
T
V
E
R
Y
A
Q
P
G
E
T
L
H
V
E
E
A
-
Q
K
A
F
G
G
G
K
G
A
N
Q
A
I
A
T
A
R
M
Q
A
D
T
T
F
I
T
K
I
G
T
D
G
V
A
D
F
I
L
E
D
F
K
V
A
H
I
D
T
S
Y
I
I
K
T
A
E
A
K
T
G
Q
A
F
I
-
T
V
N
A
E
-
G
Q
N
T
I
Y
V
Y
G
G
A
N
M
T
M
T
P
E
D
V
I
N
A
K
D
A
I
I
N
A
D
F
V
V
A
Q
L
E
V
P
I
P
A
I
I
S
A
F
E
I
A
K
A
H
G
V
T
T
V
L
N
P
A
P
A
---
K
--
A
L
P
N
E
L
L
S
L
I
D
I
I
V
P
N
E
T
E
A
E
L
L
-----
S
G
I
K
V
-----
T
---
N
E
Q
S
M
K
D
N
A
N
Y
F
L
---
S
---
I
G
I
K
T
----
V
L
---------
I
T
L
G
K
Q
G
T
Y
F
A
T
K
N
Q
--
S
Q
H
I
E
A
Y
K
V
N
A
I
D
T
T
A
A
G
D
T
F
I
G
A
F
V
S
R
L
N
K
--
S
----
Q
----
D
N
L
A
D
----
A
I
D
F
G
N
K
A
S
S
L
T
V
Q
K
H
G
A
Q
A
S
I
P
L
L
E
E
V
N
Q
V
----