@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu36070: (2016-07-31 )
MGHYSHSDIEEAVKSAKKEGLKDYLYQEPHGKKRSHKKSHRTHKKSRSHKKSYCSHKKSRSHKKSFCSHKKSRSHKKSYCSHKKSRSHKKSYRSHKKSRSYKKSYRSYKKSRSYKKSCRSYKKSRSYKKSYCSHKKKSRSYKKSCRTHKKSYRSHKKYYKKPHHHCDDYKRHDDYDSKKEYWKDGNCWVVKKKYK
Atome Classification :
(20 SA)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------........-.10....-------....---------20--------...-....-..30-------------------.-.......40.--...--....50........60.......--------.70........80-........90........100-----........110....---...120.......130-.-......-.-.----140.......-150....---------------...160-----....-------....170.---------------..------....180---.--------..---.-.---...190...--------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGHY
S
H
S
D
-
I
E
E
A
V
K
S
-------
A
K
K
E
---------
G
---------
L
K
D
-
Y
LYQ-EPHG-------------------K-KR
S
H
K
K
S
H
R
T
--
H
K
K
--
S
R
S
H
K
K
S
Y
C
S
HKKS
R
S
H
K
K
S
F
C
S
--------
H
K
KSR
S
H
K
K
S
Y
C
S
-
H
K
K
S
R
S
H
K
K
S
Y
R
S
H
K
K
S
R
S
Y
------
K
K
S
Y
R
S
Y
K
K
S
R
S
Y
K
K
---
S
C
R
S
Y
K
K
S
R
S
Y
K
K
S
---
Y
-
C
S
H
K
K
K
-
S
-
R
----
S
Y
K
K
S
C
R
T
H
K
-
K
S
Y
R
S
H
K
---------------
K
Y
YKK------PHHH-------CD
D
Y
KRHD---------------DY------D
S
K
K
E
Y----W--------KD---G-
N
---
C
W
V
V
K
KKYK--------------------------------------------------------
33
Fugue
54.42
19%
98
- C3 -
4UX8
-
GFRA1_RAT
C:
[25-343]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------DRLDCVKASDQCLKEQSCSTKYRTLRQCVAGKETN
F
S
L
T
S
G
L
E
-
A
K
D
E
C
R
S
-------
A
M
E
A
---------
L
---------
K
Q
K
-
S
L
Y
N
-
C
R
C
K
-------------------
R
G
M
K
K
E
K
N
C
L
R
I
--
Y
W
S
--
M
Y
Q
S
K
G
N
N
C
L
D
A
A
K
A
C
N
L
D
D
T
C
----------
K
K
Y
R
S
A
Y
I
T
P
C
T
-
T
S
M
S
N
E
V
C
N
R
R
K
C
H
K
A
L
R
Q
F
------
F
D
K
V
---
P
A
K
H
S
Y
G
M
LFC
S
C
R
D
I
A
C
T
E
R
R
R
Q
T
IVP
V
-
C
S
Y
E
E
R
-
E
-
R
PNCL
S
L
Q
D
S
C
K
T
N
Y
-
I
C
R
S
R
L
A
---------------
D
F
F
T
N
CQPESR
S
V
S
N
-------
C
L
K
E
N
Y
A
D
CLLAYSGLIGTVMTP
N
Y
------
V
D
S
S
S
L
SVAP
W
CDCSNSGN
D
L
---
E
-
D
---
C
L
K
F
L
N
F
F
K
DNTCLKNAIQAFGNG-----------------------------------------
28
Fugue
50.85
14%
152
- C- -
2AUA
-
?
A:
[-11-195]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
--
E
T
E
F
Y
A
-------
Y
H
I
V
---------
T
---------
R
K
K
M
H
I
G
Q
M
I
P
F
N
-------------------
K
-
N
Q
H
N
T
L
Y
H
F
F
--
F
E
R
--
E
Q
L
N
A
N
G
E
D
G
I
Q
I
L
N
N
H
Y
K
N
D
E
L
--------
H
I
N
N
E
N
A
K
V
V
I
S
Y
M
D
Q
T
I
R
A
A
R
E
T
I
V
E
M
----
V
R
------
L
Q
E
F
P
E
Y
P
S
R
L
S
C
L
Y
---
A
A
K
S
Y
E
D
A
L
K
W
K
A
L
---
F
-
D
S
Y
N
R
E
-
V
-
L
----
Q
I
V
K
-
L
R
V
I
G
-
S
S
F
E
G
D
G
---------------
N
L
L
P
K
------
E
-----------
D
G
I
P
F
S
Q
---------------
K
I
------
E
Q
A
R
K
Y
----
W
--------
K
G
---
N
-
N
ELP
E
L
L
I
N
G
E
I
E
VVEIIDDF------------------------------------------------
29
Fugue
46.72
15%
107
- C4 -
4PEV
1
?
A:
[52-421]
P
I
S
V
L
V
L
F
DVGGRGDLS
F
N
D
M
A
A
L
G
A
D
R
A
A
E
E
LG
V
D
V
V
F
Q
T
P
QSLAV
M
E
S
V
L
D
A
A
S
R
S
GEYD
L
I
V
L
V
G
FLW
Q
E
P
L
E
K
V
APRYPE
Q
K
Y
A
L
I
DAATRERYDN
V
A
S
Y
L
F
R
E
Q
E
V
A
S
L
V
G
I
I
A
A
D
I
A
N
N
I
S
K
A
T
G
E
E
A
K
A
G
A
VAGMDI
P
P
L
W
R
F
H
I
G
Y
L
Y
G
V
Q
Y
Y
N
Q
A
M
GTD
V
E
M
V
W
T
Y
TGRFDD
P
T
L
G
K
T
T
A
E
Q
M
L
Q
Q
GVR
V
F
Y
G
V
A
G
L
T
H
V
G
M
F
-
N
A
V
K
E
-------
A
A
A
R
---------
G
---------
V
I
A
-
F
S
I
G
-
Q
D
A
S
-------------------
Q
-
E
W
Y
D
P
Q
T
----------------
I
I
I
S
G
L
K
R
-------
V
D
--------
V
A
V
Y
T
A
I
K
D
V
V
E
G
-
R
F
R
G
G
I
V
S
L
G
L
K
E
G
G
L
G
L
S
D
------
E
E
I
I
R
Y
F
A
E
I
A
A
E
T
G
---
Q
L
P
E
G
L
T
P
E
K
V
V
E
I
---
V
M
S
Q
R
E
K
W
I
S
-
N
----
D
G
W
R
L
V
E
E
L
K
-
Q
K
I
I
S
G
E
---------------
I
K
F
V
T
------
P
Q
D
--------------
H
D
---------------
T
Y
------
D
S
I
I
E
E
----
L
--------
K
A
---
G
-
N
------
L
E
A
A
L
E
--------------------------------------------------------
26
Fugue
46.06
15%
130
* C5 *
4IAP
5
ENLYS_BPT4 (first)
A:
[5-260]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
R
Y
L
Q
G
Y
-
L
L
K
K
R
R
V
DN
I
F
E
M
L
R
I
D
E
---------
G
---------
L
R
L
-
K
I
Y
K
-
N
T
E
G
YYTIGIGHLLTKSPS
L
N
A
A
K
-
S
E
L
D
K
A
I
G
R
N
--
T
N
G
VI
T
K
D
E
A
E
K
L
F
N
Q
D
V
D
A
A
V
R
G
I
L
R
N
--------
A
K
L
K
P
V
Y
D
S
L
D
A
V
-
R
R
A
A
L
I
N
M
V
F
Q
M
G
E
T
G
V
A
G
F
------
T
N
S
L
R
M
L
Q
Q
K
R
-
W
D
E
---
A
A
V
N
L
A
K
S
R
W
Y
N
Q
T
--------
P
N
R
-
A
-
K
----
R
V
I
T
T
F
R
T
G
T
W
D
A
Y
V
D
Q
G
F
K
K
R
F
F
T
L
D
FRYG
T
L
S
Y
Y
L
N
------
D
H
N
Q
TCRGEIV
I
S
L
S
S
V
S
A
---------------
N
K
------
K
D
K
I
I
I
----
I
--------
D
S
---
G
M
E
---
V
W
V
L
K
A
T
T
K
E
N
W
Q
S
W
V
D
A
L
Q
T
C
F
D-----------------------------------------
30
Fugue
45.11
10%
71
- C5 -
4K5Y
7
CRFR1_HUMAN (first)
A:
[13-423]
-------------------H
Y
H
V
A
A
I
I
N
Y
L
G
H
C
I
S
L
V
A
L
L
V
A
F
V
L
F
L
R
ARSIRC
L
R
N
I
I
H
A
N
L
I
A
A
F
I
L
R
N
A
T
W
F
V
V
Q
L
T
M
S
P
E
V
H
Q
S
NV
G
W
C
R
L
V
T
A
A
Y
N
Y
F
H
V
T
N
F
F
W
M
F
G
E
G
C
Y
L
H
T
A
I
V
L
T
N
I
F
E
M
L
R
I
D
EGLRL
K
I
Y
K
D
TEGYYTIGIGHLLTKSPS
L
S
V
A
K
S
E
L
D
K
A
I
GRNSNGVIT
K
D
E
A
E
K
L
F
N
Q
D
V
D
A
A
V
R
G
I
L
R
N
A
K
L
K
P
-
V
Y
D
S
L
D
A
-------
V
R
R
S
---------
A
---------
L
I
N
-
M
V
F
Q
-
M
G
E
T
-------------------
G
-
V
A
G
F
T
N
S
L
R
M
--
L
Q
Q
--
K
R
--------------
W
D
E
A
A
V
N
--------
L
A
K
S
R
W
Y
N
Q
T
----
P
N
R
A
K
R
V
I
A
T
F
R
T
G
--------------
T
W
D
A
Y
D
R
L
R
A
W
M
F
---
I
C
I
G
W
G
V
P
F
P
I
I
V
A
---
W
-
A
I
G
K
L
Y
-
Y
-
D
----
N
E
K
--
C
W
A
G
K
-
R
P
G
V
Y
T
D
---------------
Y
I
Y
Q
G
------
P
M
A
L
-------
V
L
L
I
N
F
I
F
---------------
L
F
------
N
I
V
R
I
L
----
M
--------
T
K
---
L
-
R
---
A
S
T
T
S
E
T
I
Q
A
R
K
A
V
K
A
T
L
V
L
L
P
L
L
G
I
T
Y
M
L
A
F
V
NE
V
S
R
V
V
F
I
Y
F
N
A
F
L
E
S
F
Q
G
F
F
V
S
V
F
A
C
F
L
N
S
15
HHSearch
43.15
38%
-216
- C1 -
4M0W
2
R1A_CVHSA
A:
[107-114]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
--------
A
D
---
N
-
N
---
S
Y
L
--------------------------------------------------------------
32
Fugue
42.83
8%
107
- C6 -
1TUE
-
VE1_HPV18
A:
[425-629]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SGSN
M
S
Q
W
I
R
F
R
-
C
S
K
I
D
E
G
-------
G
D
W
R
---------
P
---------
I
V
Q
-
F
L
R
Y
-
Q
Q
I
E
-------------------
F
-
I
T
F
L
G
A
L
K
S
F
--
L
K
G
---
T
P
K
K
N
C
L
V
F
C
G
P
A
N
T
G
K
S
Y
F
G
M
S
F
I
H
F
I
Q
G
A
V
I
S
F
V
N
S
T
S
H
F
W
-
L
E
P
L
T
D
T
K
V
A
M
L
D
D
A
T
T
T
C
W
------
T
Y
F
D
T
Y
M
R
N
A
L
D
G
N
P
---
I
S
I
D
P
L
I
Q
L
K
C
P
P
I
---
L
-
L
T
T
N
I
H
-
P
-
A
----
K
D
N
-----
R
W
-
P
Y
L
E
S
R
I
---------------
T
V
F
E
F
------
P
N
A
F
-------
P
F
D
K
N
G
N
P
---------------
V
Y
------
E
I
N
D
K
N
----
W
--------
K
C
-----------
F
F
E
R
T
W
S
RLDL----------------------------------------------------
31
Fugue
40.35
9%
-4
- C5 -
1QLE
4
COX3_PARDE
C:
[1-273]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------AHVKNHDY
Q
I
L
P
P
SI
W
P
F
F
G
A
I
G
A
F
V
M
L
T
G
A
V
A
W
M
K
G
I
T
F
F
G
-
L
P
V
E
G
P
W
-------
M
F
L
I
---------
G
---------
L
V
G
-
V
L
Y
V
-
M
F
G
W
-------------------
W
-
A
D
V
V
N
E
G
E
-
T
GE
H
T
P
--
V
V
R
I
G
L
Q
Y
G
F
I
L
F
I
M
S
E
V
M
F
F
V
A
--------
W
F
W
A
F
I
K
N
A
L
Y
P
M
-
G
P
D
S
-
P
I
K
D
G
V
W
P
P
E
G
I
V
T
F
------
D
P
W
H
L
P
L
I
N
T
L
I
L
L
L
---
S
G
V
A
V
T
W
A
H
H
A
F
V
L
-----
E
G
D
R
K
T
-
T
-
I
----
N
G
L
I
V
A
V
I
L
G
-
V
C
F
T
G
L
Q
---------------
A
Y
E
Y
S
------
H
A
---------
A
F
G
L
-
A
D
T
---------------
V
Y
------
A
G
A
F
Y
M
----
A
--------
T
G
---
F
-
H
---
G
A
H
V
I
I
G
T
I
F
L
F
V
C
L
I
R
L
LKGQMTQKQH
V
G
F
E
A
A
A
W
Y
W
H
F
V
D
V
V
W
L
F
L
F
V
V
I
YIWGR--------
34
Fugue
38.45
8%
123
* C6 *
1ZLP
2
PDP_DIACA
A:
[28-311]
------------------------------------------------------------------------------------------------------------------------KT
T
M
H
R
L
I
E
E
HG
S
V
L
M
P
G
V
Q
D
A
L
S
A
A
V
V
E
K
T
GFHAAFVS
G
Y
S
V
S
A
AMLGLPDFGLLT
T
T
E
V
V
E
A
T
R
R
I
T
A
A
A
PNLCVVVDGD
T
G
G
G
G
P
L
N
-
V
Q
R
F
I
R
E
-------
L
I
S
A
---------
G
---------
A
K
G
-
V
F
L
E
-
D
Q
V
W
-------------------
P
-
K
K
C
---
G
H
M
R
--
G
K
A
--
V
V
P
A
E
E
H
A
L
K
I
A
A
A
R
E
A
I
G
D
S
D
F
--------
F
L
V
A
R
T
D
A
R
A
P
H
G
-
L
E
E
G
I
R
R
A
N
L
Y
K
E
A
G
A
D
A
T
F
VEAPAN
V
D
E
L
K
E
V
S
A
K
T
K
G
L
R
---
I
A
N
M
I
E
G
G
K
T
P
L
H
T
---
P
-
E
E
F
K
E
M
-
G
F
H
----
L
I
A
H
S
L
T
A
V
Y
-
A
T
A
R
A
L
V
---------------
N
I
M
K
I
------
L
K
E
K
-------
G
T
T
R
D
D
L
D
---------------
Q
M
------
A
T
F
S
E
F
----
N
--------
E
L
I
S
L
E
-
S
---
W
Y
E
M
E
S
K
F
K
--------------------------------------------------------
8
HHSearch
35.19
25%
-173
- C7 -
4WZS
-
?
B:
[67-94]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
S
Y
E
H
-
V
Y
K
A
L
K
N
-------
L
------------
G
---------
F
E
S
-
Y
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
33.81
25%
-197
- C7 -
1JFI
1
NC2B_HUMAN
B:
[68-87]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
S
P
E
H
-
V
I
Q
A
L
E
S
-------
L
------------
G
---------
F
G
S
-
Y
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
32.72
17%
-177
- C7 -
4CSR
2
NFYB_HUMAN
A:
[63-85]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
N
G
E
D
-
I
L
F
A
M
S
T
-------
L
G
F
D
---------
S
---------
Y
V
E
-
P
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
32.52
32%
-91
* C7 *
3CUQ
-
SNF8_HUMAN
A:
[138-156]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
S
Q
D
D
-
L
I
R
A
I
K
K
-------
L
K
A
L
---------
G
---------
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
32.46
26%
-164
- C7 -
3CUQ
-
VPS36_HUMAN
B:
[281-299]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
S
P
E
D
-
L
V
N
A
C
K
M
-------
L
E
A
L
---------
K
---------
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
31.66
27%
-87
- C7 -
3WR2
1
RNPO_PLEOS
A:
[13-34]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
F
T
G
T
D
-
V
T
N
A
I
R
S
-------
A
R
A
G
---------
G
---------
S
G
N
-
Y
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
31.60
35%
53
- C7 -
1FN9
1
SIGM3_REOVD
A:
[62-98]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
R
---------------
K
L
K
H
L
------
P
H
H
R
-------
C
N
Q
Q
I
R
H
Q
---------------
D
Y
V
D
V
Q
F
A
D
R
V
T
A
H
----
W
--------
K
R
---
G
----------------------------------------------------------------------
3
PsiBlast_PDB
31.37
35%
59
- C7 -
1JMU
3
SIGM3_REOVL
G:
[62-98]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
R
---------------
K
L
K
H
L
------
P
H
H
R
-------
C
N
Q
Q
I
R
H
Q
---------------
D
Y
VDVQFA
D
R
V
T
A
H
----
W
--------
K
R
---
G
----------------------------------------------------------------------
12
HHSearch
30.05
15%
-82
- C7 -
4C4P
-
B:
[44-78]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
S
L
T
Y
E
E
-
V
L
Q
E
L
V
K
-------
H
K
E
L
L
R
R
K
D
T
H
I
R
E
---------
L
E
D
-
Y
I
D
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
29.87
25%
-69
- C7 -
1U5T
-
VPS36_YEAST
B:
[454-473]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
S
P
M
E
-
M
R
E
A
C
E
R
-------
F
E
H
L
---------
G
---------
L
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
29.84
15%
-52
- C7 -
3TSO
1
RFIP2_HUMAN
C:
[12-46]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
S
L
T
Y
E
E
-
V
L
Q
E
L
V
K
-------
H
K
E
L
---------
L
R
R
K
D
T
H
I
R
E
L
E
D
-
Y
I
D
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------