@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu36700: (2016-08-01 )
MITESRQMLDKRNRPLRDLRISVTDRCNFRCTYCMPAELFGPDYPFLKKEELLSFEELERLATLFVTRFGVEKIRLTGGEPLMRKDMPELIKKLARIPGIRDIAMTTNGSLLPVYAKRLKEAGLKRVTISLDSLEDERFKKINGRGVSVSKVLEGIEAAKQAGLGVKINMVVQKGVNEKDILPMARYFKEKGHILRFIEFMDVGNTNQWEKKDVMTKAEIIDLINKHMPVEPIAPNYIGEVASRFRYLDGSGEIGVISSVSDAFCGSCNRARLSARGELFTCLFASSGFDLRAPVRQELSDDELSEMIGTVWKNRIDQYSVDRTLSKASGKKKVEMSYIGG
Atome Classification :
(20 SA)
----------------------------------------.........10..---......20.-...-....30....----------------....40........50........60........-70......-..80.-...-----..---...90........100.----......110------..-.-......120.-.......130---.-......140..--.--..-.--.150.......160...-....170....--...180.......190-.-......200.......210.......220.......230.......240.......250.......260.-......270...-....280....-.-..290.......300.......310.......320....---...330.........340------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------MIT
E
S
R
Q
M
L
D
KRN---RPLR
D
L
R
I
S
-VTD-RCN
F
R
C
T
YCM----------------
P
A
E
LFGPDYPFL
K
K
E
E
LL
S
F
E
E
L
E
R
L
A
T
L
F
V
T
RF-G
V
E
K
I
RLT-GGE-P-
L
M
R
-----
K
D
---
M
P
E
L
I
K
K
L
A
RIPG
I
R
D
I
----
A
MTTNGS--------
L
L
-
P
-
V
Y
A
K
R
L
K
E-A-GL
K
R
V
T
I
SLD---S-L
E
D
E
R
F
K
KING--R--GV-
S
--
V
S
K
V
L
E
G
I
E
A
A
K
QAGL
G
-
V
K
I
N
M
V
V
QKGV--
N
E
K
DI
L
P
M
A
R
Y
F
K
EKG-
H
-
I
L
R
F
I
E
F
M
DVGNTN
Q
W
E
K
K
D
V
M
T
K
A
E
I
I
D
L
I
N
KHMPVEPIA
P
N
Y
I
G
E
V
A
S
R
F
R
YLDGSGE
I
G
V
I
SS
V
S
D
A
-
F
CGSC
N
R
A
R
LSA-RG
E
L
F
T
C
L
FAS-S-GFDLR
A
P
V
R
Q
EL
S
D
D
E
L
S
E
M
I
G
T
V
W
K
N
R
I
D
Q
Y
S
V
D
R
T
L
S
---KASG--K
K
K
V
E
M
SYIGG-------------------------------------------------------
35
HHSearch
93.91
50%
-95
- C2 -
1TV8
5
MOAA_STAA8
A:
[4-329]
----------------------------------------------
Q
I
K
D
K
L
G
---
R
P
I
R
D
L
R
L
S
-
V
T
D
-
R
C
N
F
R
C
D
Y
C
M
----------------
P
K
E
V
F
G
D
D
F
V
F
L
P
K
N
E
L
L
T
F
D
E
M
A
R
I
A
K
V
Y
A
-
E
L
-
G
V
K
K
I
R
I
T
-
G
G
E
-
P
-
L
M
R
-----
R
D
---
L
D
V
L
I
A
K
L
N
Q
I
D
G
I
E
D
I
----
G
L
T
T
N
G
L
--------
L
L
-
K
-
K
H
G
Q
K
L
Y
D
-
A
-
G
L
R
R
I
N
V
S
L
D
---
A
-
I
D
D
T
L
F
Q
S
I
N
N
--
R
--
N
I
-
K
--
A
T
T
I
L
E
Q
I
D
Y
A
T
S
I
G
L
N
-
V
K
V
N
V
V
I
Q
K
G
I
--
N
D
D
Q
I
I
P
M
L
E
Y
F
K
D
K
H
-
I
-
E
I
R
F
I
E
F
M
D
V
G
N
D
N
G
W
D
F
S
K
V
V
T
K
D
E
M
L
T
M
I
E
Q
H
F
E
I
D
P
V
E
P
K
Y
F
G
E
V
A
K
Y
Y
R
H
K
D
N
G
V
Q
F
G
L
I
T
S
V
S
Q
S
-
F
C
S
T
C
T
R
A
R
L
S
S
-
D
G
K
F
Y
G
C
L
F
A
T
-
V
D
G
F
N
V
K
A
F
I
R
S
G
V
T
D
E
E
L
K
E
Q
F
K
A
L
W
Q
I
R
D
D
R
Y
S
D
E
R
T
A
Q
T
V
A
N
R
Q
---------------------------------------------------------------------
22
PsiBlast_CBE
93.76
49%
-98
- C2 -
1TV8
4
MOAA_STAA8
B:
[4-329]
----------------------------------------------
Q
I
K
D
K
L
G
---
R
P
I
R
D
L
R
L
S
-
V
T
D
-
R
C
N
F
R
C
D
Y
C
M
----------------
P
K
E
V
F
G
D
D
F
V
F
L
P
K
N
E
L
L
T
F
D
E
M
A
R
I
A
K
V
Y
-
A
E
L
-
G
V
K
K
I
R
I
T
-
G
G
E
-
P
-
L
M
R
-----
R
D
---
L
D
V
L
I
A
K
L
N
Q
I
D
G
I
E
D
I
----
G
L
T
T
N
G
L
--------
L
L
-
K
-
K
H
G
Q
K
L
Y
D
-
A
-
G
L
R
R
I
N
V
S
L
D
---
A
-
I
D
D
T
L
F
Q
S
I
N
N
--
R
--
N
I
-
K
--
A
T
T
I
L
E
Q
I
D
Y
A
T
S
I
G
L
N
-
V
K
V
N
V
V
I
Q
K
G
I
--
N
D
D
Q
I
I
P
M
L
E
Y
F
K
D
K
H
-
I
-
E
I
R
F
I
E
F
M
D
V
G
N
D
N
G
W
D
F
S
K
V
V
T
K
D
E
M
L
T
M
I
E
Q
H
F
E
I
D
P
V
E
P
K
Y
F
G
E
V
A
K
Y
Y
R
H
K
D
N
G
V
Q
F
G
L
I
T
S
V
S
Q
S
-
F
C
S
T
C
T
R
A
R
L
S
S
-
D
G
K
F
Y
G
C
L
F
A
T
V
D
-
G
F
N
V
K
A
F
I
R
S
G
V
T
D
E
E
L
K
E
Q
F
K
A
L
W
Q
I
R
D
D
R
Y
S
D
E
R
T
A
Q
---
T
V
A
N
R
Q------------------------------------------------------------------
2
PsiBlast_PDB
93.48
49%
-95
- C2 -
1TV8
5
MOAA_STAA8
A:
[4-329]
----------------------------------------------
Q
I
K
D
K
L
G
---
R
P
I
R
D
L
R
L
S
-
V
T
D
-
R
C
N
F
R
C
D
Y
C
M
----------------
P
K
E
V
F
G
D
D
F
V
F
L
P
K
N
E
L
L
T
F
D
E
M
A
R
I
A
K
V
Y
-
A
E
L
-
G
V
K
K
I
R
I
T
-
G
G
E
-
P
-
L
M
R
-----
R
D
---
L
D
V
L
I
A
K
L
N
Q
I
D
G
I
E
D
I
----
G
L
T
T
N
G
L
--------
L
L
-
K
-
K
H
G
Q
K
L
Y
D
-
A
-
G
L
R
R
I
N
V
S
L
D
---
A
-
I
D
D
T
L
F
Q
S
I
N
N
--
R
--
N
I
-
K
--
A
T
T
I
L
E
Q
I
D
Y
A
T
S
I
G
L
N
-
V
K
V
N
V
V
I
Q
K
G
I
--
N
D
D
Q
I
I
P
M
L
E
Y
F
K
D
K
H
-
I
-
E
I
R
F
I
E
F
M
D
V
G
N
D
N
G
W
D
F
S
K
V
V
T
K
D
E
M
L
T
M
I
E
Q
H
F
E
I
D
P
V
E
P
K
Y
F
G
E
V
A
K
Y
Y
R
H
K
D
N
G
V
Q
F
G
L
I
T
S
V
S
Q
S
-
F
C
S
T
C
T
R
A
R
L
S
S
-
D
G
K
F
Y
G
C
L
F
A
T
V
D
-
G
F
N
V
K
A
F
I
R
S
G
V
T
D
E
E
L
K
E
Q
F
K
A
L
W
Q
I
R
D
D
R
Y
S
D
E
R
T
A
Q
---
T
V
A
N
R
Q------------------------------------------------------------------
24
PsiBlast_CBE
93.44
48%
-101
- C2 -
2FB2
4
MOAA_STAA8
B:
[4-329]
----------------------------------------------
Q
I
K
D
K
L
G
---
R
P
I
R
D
L
A
L
S
-
V
T
D
-
R
C
N
F
R
C
D
Y
C
M
----------------
P
K
E
V
F
G
D
D
F
V
F
L
P
K
N
E
L
L
T
F
D
E
M
A
R
I
A
K
V
Y
-
A
E
L
-
G
V
K
K
I
R
I
T
-
G
G
E
-
P
-
L
M
R
-----
R
D
---
L
D
V
L
I
A
K
L
N
Q
I
D
G
I
E
D
I
----
G
L
T
T
N
G
L
--------
L
L
-
K
-
K
H
G
Q
K
L
Y
D
-
A
-
G
L
R
R
I
N
V
S
L
D
---
A
-
I
D
D
T
L
F
Q
S
I
N
N
--
R
--
N
I
-
K
--
A
T
T
I
L
E
Q
I
D
Y
A
T
S
I
G
L
N
-
V
K
V
N
V
V
I
Q
K
G
I
--
N
D
D
Q
I
I
P
M
L
E
Y
F
K
D
K
H
-
I
-
E
I
R
F
I
E
F
M
D
V
G
N
D
N
G
W
D
F
S
K
V
V
T
K
D
E
M
L
T
M
I
E
Q
H
F
E
I
D
P
V
E
P
K
Y
F
G
E
V
A
K
Y
Y
R
H
K
D
N
G
V
Q
F
G
L
I
T
S
V
S
Q
S
-
F
C
S
T
C
T
A
A
A
L
S
S
-
D
G
K
F
Y
G
C
L
F
A
T
V
D
-
G
F
N
V
K
A
F
I
R
S
G
V
T
D
E
E
L
K
E
Q
F
K
A
L
W
Q
I
R
D
D
R
Y
S
D
E
R
T
A
Q
---
T
V
A
N
R
Q------------------------------------------------------------------
4
PsiBlast_PDB
93.44
48%
-95
- C2 -
2FB2
4
MOAA_STAA8
A:
[4-329]
----------------------------------------------
Q
I
K
D
K
L
G
---
R
P
I
R
D
L
A
L
S
-
V
T
D
-
R
C
N
F
R
C
D
Y
C
M
----------------
P
K
E
V
F
G
D
D
F
V
F
L
P
K
N
E
L
L
T
F
D
E
M
A
R
I
A
K
V
Y
-
A
E
L
-
G
V
K
K
I
R
I
T
-
G
G
E
-
P
-
L
M
R
-----
R
D
---
L
D
V
L
I
A
K
L
N
Q
I
D
G
I
E
D
I
----
G
L
T
T
N
G
L
--------
L
L
-
K
-
K
H
G
Q
K
L
Y
D
-
A
-
G
L
R
R
I
N
V
S
L
D
---
A
-
I
D
D
T
L
F
Q
S
I
N
N
--
R
--
N
I
-
K
--
A
T
T
I
L
E
Q
I
D
Y
A
T
S
I
G
L
N
-
V
K
V
N
V
V
I
Q
K
G
I
--
N
D
D
Q
I
I
P
M
L
E
Y
F
K
D
K
H
-
I
-
E
I
R
F
I
E
F
M
D
V
G
N
D
N
G
W
D
F
S
K
V
V
T
K
D
E
M
L
T
M
I
E
Q
H
F
E
I
D
P
V
E
P
K
Y
F
G
E
V
A
K
Y
Y
R
H
K
D
N
G
V
Q
F
G
L
I
T
S
V
S
Q
S
-
F
C
S
T
C
T
A
A
A
L
S
S
-
D
G
K
F
Y
G
C
L
F
A
T
V
D
-
G
F
N
V
K
A
F
I
R
S
G
V
T
D
E
E
L
K
E
Q
F
K
A
L
W
Q
I
R
D
D
R
Y
S
D
E
R
T
A
Q
---
T
V
A
N
R
Q------------------------------------------------------------------
25
Fugue
93.11
49%
-93
- C2 -
1TV8
5
MOAA_STAA8
A:
[3-329]
---------------------------------------------
E
Q
I
K
D
K
L
G
---
R
P
I
R
D
L
R
L
S
-
V
T
D
-
R
C
N
F
R
C
D
Y
C
M
----------------
P
K
E
V
F
G
D
D
F
V
F
L
P
K
N
E
L
L
T
F
D
E
M
A
R
I
A
K
V
Y
A
E
-
L
-
G
V
K
K
I
R
I
T
-
G
G
E
-
P
-
L
M
R
-----
R
D
---
L
D
V
L
I
A
K
L
N
Q
I
D
G
I
E
D
I
----
G
L
T
T
N
G
L
--------
L
L
-
K
-
K
H
G
Q
K
L
Y
D
-
A
-
G
L
R
R
I
N
V
S
L
D
---
A
-
I
D
D
T
L
F
Q
S
I
N
N
--
R
--
N
I
-
K
--
A
T
T
I
L
E
Q
I
D
Y
A
T
S
I
G
L
N
-
V
K
V
N
V
V
I
Q
K
G
I
--
N
D
D
Q
I
I
P
M
L
E
Y
F
K
D
K
H
-
I
-
E
I
R
F
I
E
F
M
D
V
G
N
D
N
G
W
D
F
S
K
V
V
T
K
D
E
M
L
T
M
I
E
Q
H
F
E
I
D
P
V
E
P
K
Y
F
G
E
V
A
K
Y
Y
R
H
K
D
N
G
V
Q
F
G
L
I
T
S
V
S
Q
S
-
F
C
S
T
C
T
R
A
R
L
S
S
-
D
G
K
F
Y
G
C
L
F
A
T
-
V
D
G
F
N
V
K
A
F
I
R
S
G
V
T
D
E
E
L
K
E
Q
F
K
A
L
W
Q
I
R
D
D
R
Y
S
D
E
R
T
A
Q
---
T
V
A
N
--
R
Q
----------------------------------------------------------------
3
PsiBlast_PDB
92.80
49%
-92
- C2 -
2FB3
6
MOAA_STAA8
A:
[4-329]
----------------------------------------------
Q
I
K
D
K
L
G
---
R
P
I
R
D
L
R
L
S
-
V
T
D
-
R
C
N
F
R
C
D
Y
C
M
----------------
P
K
E
V
F
G
D
D
F
V
F
L
P
K
N
E
L
L
T
F
D
E
M
A
R
I
A
K
V
Y
-
A
E
L
-
G
V
K
K
I
R
I
T
-
G
G
E
-
P
-
L
M
R
-----
R
D
---
L
D
V
L
I
A
K
L
N
Q
I
D
G
I
E
D
I
----
G
L
T
T
N
G
L
--------
L
L
-
K
-
K
H
G
Q
K
L
Y
D
-
A
-
G
L
R
R
I
N
V
S
L
D
---
A
-
I
D
D
T
L
F
Q
S
I
N
N
--
R
--
N
I
-
K
--
A
T
T
I
L
E
Q
I
D
Y
A
T
S
I
G
L
N
-
V
K
V
N
V
V
I
Q
K
G
I
--
N
D
D
Q
I
I
P
M
L
E
Y
F
K
D
K
H
-
I
-
E
I
R
F
I
E
F
M
D
V
G
N
D
N
G
W
D
F
S
K
V
V
T
K
D
E
M
L
T
M
I
E
Q
H
F
E
I
D
P
V
E
P
K
Y
F
G
E
V
A
K
Y
Y
R
H
K
D
N
G
V
Q
F
G
L
I
T
S
V
S
Q
S
-
F
C
S
T
C
T
R
A
R
L
S
S
-
D
G
K
F
Y
G
C
L
F
A
T
V
D
-
G
F
N
V
K
A
F
I
R
S
G
V
T
D
E
E
L
K
E
Q
F
K
A
L
W
Q
I
R
D
D
R
Y
S
D
E
R
T
A
Q
---
T
V
A
N
R
Q------------------------------------------------------------------
1
PsiBlast_PDB
92.33
49%
-93
- C2 -
1TV7
3
MOAA_STAA8
A:
[4-329]
----------------------------------------------
Q
I
K
D
K
L
G
---
R
P
I
R
D
L
R
L
S
-
V
T
D
-
R
C
N
F
R
C
D
Y
C
M
----------------
P
K
E
V
F
G
D
D
F
V
F
L
P
K
N
E
L
L
T
F
D
E
M
A
R
I
A
K
V
Y
-
A
E
L
-
G
V
K
K
I
R
I
T
-
G
G
E
-
P
-
L
M
R
-----
R
D
---
L
D
V
L
I
A
K
L
N
Q
I
D
G
I
E
D
I
----
G
L
T
T
N
G
L
--------
L
L
-
K
-
K
H
G
Q
K
L
Y
D
-
A
-
G
L
R
R
I
N
V
S
L
D
---
A
-
I
D
D
T
L
F
Q
S
I
N
N
--
R
--
N
I
-
K
--
A
T
T
I
L
E
Q
I
D
Y
A
T
S
I
G
L
N
-
V
K
V
N
V
V
I
Q
K
G
I
--
N
D
D
Q
I
I
P
M
L
E
Y
F
K
D
K
H
-
I
-
E
I
R
F
I
E
F
M
D
V
G
N
D
N
G
W
D
F
S
K
V
V
T
K
D
E
M
L
T
M
I
E
Q
H
F
E
I
D
P
V
E
P
K
Y
F
G
E
V
A
K
Y
Y
R
H
K
D
N
G
V
Q
F
G
L
I
T
S
V
S
Q
S
-
F
C
S
T
C
T
R
A
R
L
S
S
-
D
G
K
F
Y
G
C
L
F
A
T
V
D
-
G
F
N
V
K
A
F
I
R
S
G
V
T
D
E
E
L
K
E
Q
F
K
A
L
W
Q
I
R
D
D
R
Y
S
D
E
R
T
A
Q
---
T
V
A
N
RQ------------------------------------------------------------------
21
PsiBlast_CBE
91.59
49%
-93
- C2 -
2FB3
5
MOAA_STAA8
B:
[4-329]
----------------------------------------------
Q
I
K
D
K
L
G
---
R
P
I
R
D
L
R
L
S
-
V
T
D
-
R
C
N
F
R
C
D
Y
C
M
----------------
P
K
E
V
F
G
D
D
F
V
F
L
P
K
N
E
L
L
T
F
D
E
M
A
R
I
A
K
V
Y
-
A
E
L
-
G
V
K
K
I
R
I
T
-
G
G
E
-
P
-
L
M
R
-----
R
D
---
L
D
V
L
I
A
K
L
N
Q
I
D
G
I
E
D
I
----
G
L
T
T
N
G
L
--------
L
L
-
K
-
K
H
G
Q
K
L
Y
D
-
A
-
G
L
R
R
I
N
V
S
L
D
---
A
-
I
D
D
T
L
F
Q
S
I
N
N
--
R
--
N
I
-
K
--
A
T
T
I
L
E
Q
I
D
Y
A
T
S
I
G
L
N
-
V
K
V
N
V
V
I
Q
K
G
I
--
N
D
D
Q
I
I
P
M
L
E
Y
F
K
D
K
H
-
I
-
E
I
R
F
I
E
F
M
D
V
G
N
D
N
G
W
D
F
S
K
V
V
T
K
D
E
M
L
T
M
I
E
Q
H
F
E
I
D
P
V
E
P
K
Y
F
G
E
V
A
K
Y
Y
R
H
K
D
N
G
V
Q
F
G
L
I
T
S
V
S
Q
S
-
F
C
S
T
C
T
R
A
R
L
S
S
-
D
G
K
F
Y
G
C
L
F
A
T
V
D
-
G
F
N
V
K
A
F
I
R
S
G
V
T
D
E
E
L
K
E
Q
F
K
A
L
W
Q
I
R
D
D
R
Y
S
D
E
R
T
A
Q
---
T
V
A
N
R
Q------------------------------------------------------------------
23
PsiBlast_CBE
91.51
49%
-92
- C2 -
1TV7
3
MOAA_STAA8
B:
[4-329]
----------------------------------------------
Q
I
K
D
K
L
G
---
R
P
I
R
D
L
R
L
S
-
V
T
D
-
R
C
N
F
R
C
D
Y
C
M
----------------
P
K
E
V
F
G
D
D
F
V
F
L
P
K
N
E
L
L
T
F
D
E
M
A
R
I
A
K
V
Y
-
A
E
L
-
G
V
K
K
I
R
I
T
-
G
G
E
-
P
-
L
M
R
-----
R
D
---
L
D
V
L
I
A
K
L
N
Q
I
D
G
I
E
D
I
----
G
L
T
T
N
G
L
--------
L
L
-
K
-
K
H
G
Q
K
L
Y
D
-
A
-
G
L
R
R
I
N
V
S
L
D
---
A
-
I
D
D
T
L
F
Q
S
I
N
N
--
R
--
N
I
-
K
--
A
T
T
I
L
E
Q
I
D
Y
A
T
S
I
G
L
N
-
V
K
V
N
V
V
I
Q
K
G
I
--
N
D
D
Q
I
I
P
M
L
E
Y
F
K
D
K
H
-
I
-
E
I
R
F
I
E
F
M
D
V
G
N
D
N
G
W
D
F
S
K
V
V
T
K
D
E
M
L
T
M
I
E
Q
H
F
E
I
D
P
V
E
P
K
Y
F
G
E
V
A
K
Y
Y
R
H
K
D
N
G
V
Q
F
G
L
I
T
S
V
S
Q
S
-
F
C
S
T
C
T
R
A
R
L
S
S
-
D
G
K
F
Y
G
C
L
F
A
T
V
D
-
G
F
N
V
K
A
F
I
R
S
G
V
T
D
E
E
L
K
E
Q
F
K
A
L
W
Q
I
R
D
D
R
Y
S
D
E
R
T
A
Q
---
T
V
A
N
R
Q------------------------------------------------------------------
32
Fugue
43.34
15%
15
- C2 -
2YX0
-
TYW1_PYRHO
A:
[11-342]
K
I
T
V
Q
A
N
P
NMP
K
E
V
A
E
L
F
R
K
Q
H
Y
E
I
V
G
R
H
S
G
V
K
L
CHW
L
K
K
S
L
T
E
G
R
F
C
Y
K
Q
K
F
YGI
H
S
H
R
C
L
Q
M
T
P
V
L
A
-
W
C
T
H
N
C
I
F
C
W
RPMENFLGTELPQPWD
D
P
A
F
I
V
E
E
S
I
K
A
Q
R
K
L
L
I
G
Y
K
P
K
V
D
K
K
K
F
E
E
A
W
--
N
P
T
H
A
A
I
S
L
S
G
E
-
P
-
M
L
Y
-----
P
Y
---
M
G
D
L
V
E
E
F
H
K
R
G
F
--
T
T
----
F
I
V
T
N
G
T
--------
I
P
-
E
-
R
L
E
E
M
I
K
E
D
K
-
L
P
T
Q
L
Y
V
S
I
T
---
A
-
P
D
I
E
T
Y
N
S
V
N
I
--
P
--
M
I
-
P
D
G
W
E
R
I
L
R
F
L
E
L
M
R
D
L
P
T
R
-
T
V
V
R
L
T
L
V
K
G
E
--
N
M
H
S
P
E
K
Y
A
K
L
I
L
K
A
R
----
P
M
F
V
E
A
--
K
A
Y
M
N
R
L
T
I
N
N
M
P
S
H
Q
D
I
R
E
F
A
E
A
L
V
-----------
K
H
L
P
G
Y
H
I
E
D
E
Y
E
P
S
R
V
V
L
I
M
R
D
-------------------------------------------------------------------
D
---
V
D
P
Q
--
G
T
G
V
E
G
R
F
I
K
H
-------------------------------------------------------
51
HHSearch
42.17
20%
-26
- C2 -
4RTB
3
?
A:
[98-293]
-----------------------------------------------------------
L
F
A
P
L
Y
-
L
S
N
-
I
C
I
N
N
C
S
Y
C
S
----------------
F
R
R
E
N
K
E
-----
L
S
R
V
R
L
S
L
E
E
A
V
D
E
A
K
A
I
R
-
E
M
-
G
H
T
R
I
L
L
V
-
M
G
E
-
E
-
P
E
D
-----
K
T
L
S
Y
L
E
E
I
I
P
A
I
Y
S
E
V
D
I
--
R
----
R
I
N
V
N
I
A
--------
P
L
-
T
L
K
G
Y
E
R
L
K
K
-
L
-
K
I
G
T
Y
Q
L
F
Q
E
---
S
-
Y
N
P
E
V
Y
R
E
V
H
L
DG
P
--
K
T
-
N
--
F
L
W
R
L
N
A
V
E
R
A
I
E
A
G
I
D
D
I
G
I
G
A
L
F
G
L
G
D
--
P
L
F
E
L
L
G
V
I
A
H
A
D
Y
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
HHSearch
41.78
18%
-20
- C2 -
3T7V
3
PYLB_METBF
A:
[61-232]
-----------------------------------------------------------
L
N
C
F
I
Y
-
F
S
T
-
Y
C
K
N
Q
C
S
F
C
Y
----------------
Y
N
C
R
N
E
------
I
N
R
Y
R
L
T
M
E
E
I
K
E
T
C
K
T
L
K
-
G
A
-
G
F
H
M
V
D
L
T
-
M
G
E
D
P
-
Y
Y
Y
-----
E
D
P
N
R
F
V
E
L
V
Q
I
V
K
E
E
L
G
L
-
P
I
----
M
-
I
S
P
G
L
--------
M
D
-
N
-
A
T
L
L
K
A
R
E
-
K
-
G
A
N
F
L
A
L
Y
Q
E
---
T
-
Y
D
T
E
L
Y
R
K
L
R
V
--
G
---
Q
-
S
--
F
D
G
R
V
N
A
R
R
F
A
K
Q
Q
G
Y
C
-
V
E
D
G
I
L
T
G
V
G
N
--
D
I
E
S
T
I
L
S
L
R
G
M
S
T
N
D
-
P
-
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
41.76
17%
38
- C2 -
1R30
5
BIOB_ECOLI
A:
[27-338]
-----------------R
P
R
W
T
L
S
Q
V
T
E
L
F
E
KP
L
L
D
L
L
F
E
A
Q
Q
V
H
R
Q
H
F
D
P
R
Q
---
V
Q
V
S
T
L
L
S
I
-
K
T
G
-
A
C
P
E
D
C
K
Y
C
P
----------------
Q
S
S
R
Y
K
T
G
L
E
---
A
E
R
L
M
E
V
E
Q
V
L
E
S
A
R
K
A
K
A
A
--
G
S
T
R
F
C
M
G
A
A
W
K
-
N
-
P
H
E
-----
R
D
---
M
P
Y
L
E
Q
M
V
Q
G
V
K
A
M
G
L
E
----
A
C
M
T
L
G
T
--------
L
S
-
E
-
S
Q
A
Q
R
L
A
N
-
A
-
G
L
D
Y
Y
N
H
N
L
D
---
T
--
S
P
E
F
Y
G
N
I
-
I
--
T
--
T
R
-
T
--
Y
Q
E
R
L
D
T
L
E
K
V
R
D
A
G
I
K
-
V
C
S
G
G
I
V
G
L
G
E
--
T
V
K
D
R
A
G
L
L
L
Q
L
A
N
L
P
-
T
-
P
P
E
S
V
P
I
N
M
L
V
K
V
K
G
----------------
T
P
L
A
D
N
D
D
V
D
A
F
D
F
I
R
T
I
A
V
A
R
I
M
M
P
T
S
Y
V
R
L
S
A
G
R
E
Q
M
-
N
E
Q
T
Q
A
M
C
F
M
A
G
-----
A
N
S
I
F
Y
G
-
C
-
K
L
-
L
T
T
P
N
P
E
E
D
K
D
L
Q
L
F
R
K
L
G
L
N
P
Q
Q
T
--------------------------------------------------------------------------------------
41
HHSearch
41.05
17%
-42
- C2 -
2A5H
5
KAMA_CLOSU
A:
[112-285]
--------------------------------------------------------
R
Y
P
D
R
V
L
L
L
-
I
T
D
-
M
C
S
M
Y
C
R
H
C
T
----------------
R
R
R
F
A
G
Q
------
S
D
D
S
M
P
M
E
R
I
D
K
A
I
D
Y
I
R
N
T
P
-
Q
V
R
D
V
L
L
S
-
G
G
D
-
A
-
L
L
V
-----
S
D
E
T
-
L
E
Y
I
I
A
K
L
R
E
I
-
P
--
H
V
----
E
I
V
R
I
G
S
RTPVVLPQ
R
I
-
T
P
E
L
V
N
M
L
K
K
-
Y
-
H
P
V
W
L
N
T
H
F
N
---
H
-
P
N
E
I
------------------
T
E
E
S
T
R
A
C
Q
L
L
A
D
A
G
V
P
-
L
G
N
Q
S
V
L
L
R
G
V
ND
C
V
H
V
M
K
E
L
V
N
K
L
V
K
I
R
-
V
-
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
40.53
27%
10
- C2 -
4K36
3
ANSME_CLOP1
A:
[3-204]
---------------------------------------------------------
P
L
S
L
L
I
K
P
-
A
S
S
-
G
C
N
L
K
C
T
Y
C
F
----------------
Y
H
S
L
--
S
D
N
--
V
K
S
Y
G
I
M
R
D
E
V
L
E
S
M
V
K
R
V
L
N
E
A
N
G
H
C
S
F
A
F
Q
-
G
G
E
-
P
T
L
A
G
-----
L
E
---
F
F
E
K
L
M
E
L
Q
R
K
H
N
Y
K
N
L
K
I
Y
N
S
L
Q
T
N
G
T
--------
L
I
D
E
-
S
W
A
K
F
L
S
E
-
N
-
K
F
-
L
V
G
L
S
M
D
---
G
P
K
E
I
H
N
L
N
R
K
D
C
--
C
--
G
L
D
T
--
F
S
K
V
E
R
A
A
E
L
F
K
K
Y
K
V
E
-
F
N
I
L
C
V
V
T
S
N
T
---
A
R
H
V
N
K
V
Y
K
Y
F
K
E
K
D
-
F
K
F
L
Q
F
I
N
C
L
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
40.26
22%
29
- C2 -
4K36
5
ANSME_CLOP1
A:
[2-392]
---------------------------------------------------------
P
P
L
S
L
L
I
K
-
P
A
S
S
G
C
N
L
K
C
T
Y
C
F
--------------------
Y
H
S
L
S
D
N
V
K
S
Y
G
I
M
R
D
E
V
L
E
S
M
V
K
R
V
L
N
E
A
N
G
H
C
S
F
A
F
Q
-
G
G
E
-
P
-
T
L
A
G
L
E
F
F
E
K
---
L
M
E
L
Q
R
K
H
N
Y
K
N
L
K
I
Y
N
----
S
L
Q
T
N
G
T
--------
L
I
D
E
-
S
W
A
K
F
L
S
E
-
N
-
K
F
-
L
V
G
L
S
M
D
GP
K
E
-
I
H
N
L
N
R
K
D
C
C
G
--
L
--
D
--
T
--
F
S
K
V
E
R
A
A
E
L
F
K
K
Y
K
V
E
-
F
N
I
L
C
V
V
T
-
S
N
--
T
A
R
H
V
N
K
V
Y
K
Y
F
K
E
K
D
F
K
-
F
L
Q
F
I
N
C
L
D
P
L
Y
E
E
K
G
K
Y
N
Y
S
L
K
P
K
D
Y
T
K
F
L
K
N
L
F
--
D
F
W
Y
E
D
F
L
N
G
N
R
V
S
I
R
Y
F
D
G
L
L
E
T
I
L
L
G
K
S
S
S
C
G
M
N
G
T
C
T
C
Q
F
V
V
E
S
D
G
S
V
Y
P
C
-----
D
-
F
Y
V
L
D
K
W
R
L
G
N
I
Q
D
M
T
M
K
E
L
F
E
T
N
K
N
H
E
F
I
K
L
S
--
F
K
V
H
---
E
E
C
K
--
K
C
K
W
F
R
L
C
K
G
G
CRRCRDSKEDSALELNYY
C
Q
S
Y
K
E
F
F
E
Y
A
F
P
R
L
I
N
V
A
N
N
IV
D
K
L
A
A
A
L
E
H
H
H
HHH
7
PsiBlast_PDB
39.52
26%
6
- C2 -
4K38
11
ANSME_CLOP1
A:
[3-194]
---------------------------------------------------------
P
L
S
L
L
I
K
P
-
A
S
S
-
G
C
N
L
K
C
T
Y
C
F
----------------
Y
H
S
L
--
S
D
N
R
N
V
K
S
Y
G
I
M
R
D
E
V
L
E
S
M
V
K
R
V
L
N
E
A
N
G
H
C
S
F
A
F
Q
-
G
G
E
-
P
T
L
A
G
-----
L
E
---
F
F
E
K
L
M
E
L
Q
R
K
H
N
Y
K
N
L
K
I
Y
N
S
L
Q
T
N
G
T
--------
L
I
D
E
-
S
W
A
K
F
L
S
E
-
N
-
K
F
-
L
V
G
L
S
M
D
---
G
P
K
E
I
H
N
L
N
R
K
D
C
--
C
--
G
L
D
T
--
F
S
K
V
E
R
A
A
E
L
F
K
K
Y
K
V
E
-
F
N
I
L
C
V
V
T
S
N
T
---
A
R
H
V
N
K
V
Y
K
Y
F
K
E
K
D
----
F
K
F
L
Q
F
I
N
C
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
39.16
26%
10
- C2 -
4K39
4
ANSME_CLOP1
A:
[3-194]
---------------------------------------------------------
P
L
S
L
L
I
K
P
-
A
S
S
-
G
C
N
L
K
C
T
Y
C
F
----------------
Y
H
----------
K
S
Y
G
I
M
R
D
E
V
L
E
S
M
V
K
R
V
L
N
E
A
N
G
H
C
S
F
A
F
Q
-
G
G
E
-
P
T
L
A
G
-----
L
E
---
F
F
E
K
L
M
E
L
Q
R
K
H
N
Y
K
N
L
K
I
Y
N
S
L
Q
T
N
G
T
--------
L
I
D
E
-
S
W
A
K
F
L
S
E
-
N
-
K
F
-
L
V
G
L
S
M
D
---
G
P
K
E
I
H
N
L
N
R
K
D
C
--
C
--
G
L
D
T
--
F
S
K
V
E
R
A
A
E
L
F
K
K
Y
K
V
E
-
F
N
I
L
C
V
V
T
S
N
T
---
A
R
H
V
N
K
V
Y
K
Y
F
K
E
K
D
----
F
K
F
L
Q
F
I
N
C
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
HHSearch
38.77
16%
-14
- C2 -
2YX0
-
TYW1_PYRHO
A:
[142-273]
------------------------------------------------------------------------------------------------------------------------------------
P
T
H
A
A
I
S
L
S
G
E
-
P
-
M
L
Y
-----
P
Y
---
M
G
D
L
V
E
E
F
H
K
-
R
G
F
-
T
T
----
F
I
V
T
N
G
T
--------
I
P
-
E
-
R
L
E
E
M
I
K
E
-
D
K
L
P
T
Q
L
Y
V
S
I
T
---
A
-
P
D
I
E
T
Y
N
S
V
N
I
--
P
MI
P
D
-
G
--
W
E
R
I
L
R
F
L
E
L
M
R
D
L
P
T
R
-
T
V
V
R
L
T
L
V
K
G
E
--
N
M
H
S
P
E
K
Y
A
K
L
I
L
K
A
R
-
P
-
M
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------