@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu38460: (2016-08-04 )
MGKNSKAIGNNHVKSVYQALLQSLKSKSVNGFSKITIETISFIKNLYPEIDSVTSKFDNSRPDQSKDLTLYLKSGETISLNLFLIKKGRRIQPKNAGAKSFLEKYFLSAEMQKIFNKEFERYYLDYLKEVVEHKKGTHYITDKRELKRLVSSHFPKFTEEINLYRDKFLFNLRETCFTLLQQFYNEKNIGFTHAFNVFFMVNDTNIITSYGKDENDVKVEKFAPASPSLKDIELYKTGKSTVGIKFGEVGLTLRFKFESDPWKSIKLATGYHEFPKEKERVNVNLKTMRRMEKLLNKHEYAKTSNNSNAIGKCHEAWTYYYFLKAFPDVIQVDPKQCVELINTYFSSINQNTLKKLYSSTSTIVDAITEKLRQKYHDYIIESIELIPDAYIKDRLDTGDLQLVLKVNNNIIVENISLKALAKRNSKITTKNPGMGSILGPTYFNMGSMESVINEVKNKFTIGEFNHRKSLEILSYEFGMKLDSATQEQLRRGIHNLLGKAMIAITIYGEGISFCKEPSEIDGEVKVHVNVPSAIQNTLTWNNELESISLRAKFSKSQKHGWSSIKLTSECQLESRK
Atome Classification :
(20 SA)
-------------........-----------.10........20.-.......30......--..40.......----.50........60-.........----70-...----.--....80.....-----...90........100.......110.---------------------.....-----.120---..--.......130..---......140..---.....150.-......160.......170.......180.......190.......200......-------.210......--.220----........230---.......240.......250.-.----.....260.......270.......280....---...-290--------.......-----------.300...---....310.......320----...------.....330......-----------.340..---.....350........360.......370--------........380--.....---..--------.------390.......400--------------------.........410...---------------...------..420..------....----.430.......440.......450--.......460.......470.......480.......490--........-.500-........510.......520.......530---.......----.540.......-550-------.......560.......570....----------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------MGKNSKAI-----------G
N
N
H
V
K
S
V
Y
Q
A
L
L
Q
-
S
L
K
SKSVNGF
S
K
I
T
I
--
E
T
I
S
F
I
K
N
L
Y
P
----
E
I
D
S
V
T
S
K
FDNS--RPDQSK
D
L
T
----
L
Y
-
L
KS----G--
E
T
I
S
L
N
L
F
L
I
K-----KGRRIQPKNA
G
A
K
S
F
L
E
K
Y
F
L
S
A
E
M
Q
K
---------------------
I
F
N
K
E
-----
F
E
-----
R
Y
--
Y
L
D
Y
L
K
E
V
V
-
E
H---KKGTHYIT
D
K
R
---
E
L
K
R
L
V
S
S
H-F
P
K
F
T
E
E
I
N
L
Y
R
D
K
F
L
F
N
L
R
E
T
C
F
T
L
L
Q
Q
F
YNEKNIG
F
T
H
A
F
N
V
F
F
M
VND
T
N
I
I
T-------SYGKDEND
V
K
--
V
E
K
-----FAPASPSL
K
D
I
---
E
L
Y
KTGK
S
T
V
G
I
K
F
GEV
G
L
T
L
-
R
----
F
K
FESDPW
K
S
I
K
L
ATG
Y
H
EFPKE
K
E
R
V
N
V
N
L
K
---
T
M
R
-
R
M
---------
E
K
L
L
N
K
H
-----------
E
YAKTSN---NSNA
I
G
K
C
HE
A
W
T
Y
Y
Y
-----
F
L
K
------AF
P
D
V
IQV
D
P
K
Q
C
V
-----------
E
L
I
N
T
Y
---
F
S
SI
N
Q
-
N
T
L
K
K
L
Y
SS
T
S
T
I
V
D
A
I
T
E
K
L
---------
R
Q
K
Y
H
D
Y
I
I
E
---
S
I
E
LI---
P
D
--------
A
------
Y
I
K
DRLDTG
D
L
----------------------
Q
L
V
L
K
VNN
N
I
-
I
V
E
N---------------I
S
L
------
K
A
L
A
KRN------SKIT----TKNPGMGSILG
P
T
YFNMG
S
M
E
S
V
I
--
N
E
V
KNKFTIGEFNHRKS
L
E
I
L
S
Y
EFGMKLD
S
A
T
Q
E
Q
L
R
----
R
G
I
H
N
L
L
G-K
A
M
--
I
A
I
T
I
YGE
G
I
S
FCKEPSEIDG
E
V
K
V
H
V
NV
P
----
S
A
I
Q
N
TL----TWNNEL
E
S
I
S
L
-
R
A
K
-------FSKSQKHGWSS
I
K
L
T
S
E
C
QLESRK----------------------------------------------------------------------------------------------------------------
33
Fugue
56.48
17%
40
- C8 -
4NNB
2
?
A:
[4-527]
-------------------------------------
T
S
L
Y
I
T
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A
P
I
G
A
V
P
K
F
L
D
P
F
E
--------
A
T
F
I
P
S
F
L
L
----
E
-----
G
F
F
D
-----
A
D
R
C
A
S
I
A
----
A
D
-
L
K
T
----
D
G
W
E
V
V
P
A
G
G
R
L
L
Q
-----
V
G
H
A
-
Q
P
I
A
H
F
P
K
P
W
L
A
A
--
L
S
N
K
L
A
R
---------------------
R
I
V
L
Q
-----
L
T
-----
T
Y
G
W
I
V
S
E
Q
G
D
L
L
W
E
H
---
E
R
Q
H
H
Y
L
P
-----------------
P
A
L
I
E
A
I
E
K
E
S
P
A
L
L
K
N
M
E
E
A
G
W
I
A
C
A
A
G
Y
W
Q
A
G
----
K
A
R
S
P
Y
L
P
I
T
-----------------------------------
P
E
A
I
T
E
E
T
I
---
R
S
M
R
A
G
A
A
V
V
H
L
H
T
R
D
L
S
D
R
R
-
R
----
I
E
I
P
G
--
L
G
V
V
T
V
G
S
Q
R
N
Q
I
V
L
D
D
Y
D
A
I
V
P
M
V
---
K
K
R
-
E
P
---------
A
A
I
L
N
L
S
-----------
T
S
V
R
G
D
R
---
H
G
A
R
S
K
L
R
R
A
H
L
K
F
Y
D
-----
D
V
G
------
S
A
P
E
V
A
S
L
S
P
A
A
V
V
F
QG
G
G
G
Y
D
NA
P
D
F
L
D
A
Q
---
F
D
H
F
E
R
V
G
T
R
P
E
V
E
V
F
N
H
A
I
V
D
N
A
T
S
L
Y
---------
R
D
R
L
L
R
T
G
K
P
---
V
L
F
M
L
VAG
V
D
--------
Q
------
Y
R
R
D
P
I
-
T
G
E
----------------------------
V
E
D
D
S
-
L
I
A
R
---------------
V
V
R
------
E
E
I
S
S
L
L
------
A
D
---------
E
S
A
D
S
H
R
R
A
V
E
L
A
I
G
Q
L
R
P
V
V
--
E
R
L
R
A
S
F
P
V
------
S
K
I
S
I
L
---------------
L
P
----
G
P
M
Q
N
L
L
V
-
D
V
A
--
L
G
L
G
L
D
G
I
R
V
G
L
---------
E
D
G
L
T
V
N
D
A
----
R
V
P
G
G
V
R
----
K
A
R
G
T
W
E
Q
V
S
L
V
R
E
E
-------
L
L
G
R
G
A
T
I
L
T
A
A
Q
V
R
D
M
F
G
L
G
I
------------------------------------------------------------------------------------------------------------------
37
Fugue
51.02
16%
17
- C6 -
4YJ1
3
?
A:
[1-615]
--------------
G
F
S
P
L
M
D
-----------
F
F
H
S
V
E
G
R
N
Y
G
E
L
R
-
S
L
T
N
E
T
Y
Q
I
S
E
N
V
R
C
--
T
F
L
S
I
Q
S
D
P
F
A
P
G
S
Q
V
R
L
V
C
P
C
T
F
S
L
E
--
K
V
L
Q
T
T
D
L
A
AAN
P
C
R
-
R
V
A
----
A
--
E
D
F
I
L
R
S
F
H
A
G
-----
Y
R
N
G
I
P
R
R
T
S
G
A
V
Q
V
L
R
P
S
Q
H
V
L
E
R
S
T
---------------------
V
G
L
V
K
-----
A
H
-----
Q
A
--
E
I
E
I
F
A
R
V
K
-
L
P
---
G
H
G
-
R
R
I
D
G
H
G
---
A
I
D
I
F
Y
N
E
L
-
V
P
L
L
E
Q
C
V
V
G
L
N
E
E
D
L
H
Q
H
V
I
C
V
H
D
Q
E
V
L
R
S
N
L
L
G
A
G
Y
-----
V
A
F
V
A
N
G
A
I
L
P
R
-------
D
A
G
N
S
D
K
P
L
R
DN
A
V
P
-----
F
Q
S
P
K
S
L
E
C
S
F
---
T
L
P
H
S
G
K
T
I
T
G
M
G
L
P
P
-
G
L
T
L
-
I
A
G
G
G
F
H
G
K
S
T
L
L
R
A
L
E
V
G
I
Y
N
H
V
P
D
D
G
R
T
Y
V
V
V
D
P
T
---
A
V
K
I
R
A
---------
E
D
R
R
S
V
H
GVDISPFINNL
P
F
G
K
T
T
N
FFV
T
A
D
A
S
G
S
T
S
Q
A
A
N
I
M
E
-----
A
L
E
------
L
G
S
Q
L
L
L
L
D
E
D
T
C
A
-----------
T
N
L
M
-
Y
---
R
D
A
L
M
Q
-
M
L
V
P
R
A
Q
E
P
I
T
P
F
V
E
R
V
A
D
L
S
---------
Q
N
H
G
V
S
S
I
M
V
I
G
G
S
G
Q
Y
F
---
P
Q
--------
A
------
R
V
V
L
V
M
N
--------------------------------
A
Y
Q
I
-
S
D
C
T
---------------
K
E
A
------
K
E
I
A
S
N
S
------
S
L
P
G
----
D
T
A
S
V
F
I
P
D
V
N
R
C
F
D
P
D
G
S
F
T
T
V
R
--
R
G
T
K
-
V
S
G
I
G
T
E
S
I
R
F
S
E
E
T
I
D
L
S
M
V
E
Q
I
V
E
E
G
Q
V
N
A
I
----
A
Q
C
L
A
L
L
Y
-
D
G
E
P
R
I
V
P
E
M
T
T
K
G
G
A
L
T
Q
L
P
S
-
P
G
G
V
C
E
I
Q
R
G
K
F
NS
N
F
S
S
M
I
A
G
C
----
C
S
H
Q
H
D
K
R
L
E
L
-
R
T
P
S
C
Y
L
P
R
G
F
T
S
A
T
R
H
I
E
I
G
A
A
L
N
R
L
R
T
L
R
T
V
T
----------------------------------------------------------------------------------------------------------------
39
Fugue
46.58
12%
43
- C9 -
3N2O
4
SPEA_VIBVY
A:
[10-639]
K
L
D
R
V
R
A
D
Y
NVHY
W
S
Q
G
F
Y
G
I
D
DQG
E
M
Y
V
SPR
S
D
N
A
H
Q
I
Q
L
S
K
I
V
K
-
Q
L
E
E
R
Q
L
N
V
P
--
V
L
V
--
R
F
P
Q
I
L
H
Q
R
V
H
----
S
I
C
D
A
F
N
Q
A
I
E
E
--
Y
Q
Y
P
N
K
Y
L
L
----
V
Y
P
I
K
V
----
N
--
Q
Q
R
E
V
V
D
E
I
L
A
-----
S
Q
A
Q
L
E
T
K
Q
L
G
L
E
A
G
S
K
P
E
L
L
A
V
L
A
M
A
QH
A
S
S
V
I
--------------
V
C
N
G
Y
-----
K
D
-----
R
E
--
Y
I
R
L
A
L
I
G
E
-
K
L
---
G
H
K
V
F
I
V
L
E
K
M
---
S
E
L
D
L
V
L
R
E
-
A
K
S
L
G
V
T
P
R
L
G
I
R
I
R
L
A
S
Q
G
A
G
K
W
Q
A
S
G
G
E
K
S
K
F
G
L
S
A
S
Q
V
L
N
V
I
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R
L
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K
E
N
Q
L
D
TLQ
L
V
H
F
H
L
G
S
Q
M
A
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I
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--
D
V
R
-----
N
G
V
N
E
S
A
R
F
Y
C
---
E
L
R
T
L
G
---
A
N
I
T
Y
F
D
V
G
G
G
L
-
A
----
I
D
Y
D
G
T
R
-
S
Q
S
S
N
S
M
N
Y
----
G
L
V
E
Y
A
R
N
I
V
N
---
T
V
G
-
D
V
---------
C
K
D
Y
K
Q
P
-----------
M
P
V
I
I
S
E
---
S
G
R
S
L
T
A
H
H
A
V
L
I
S
N
V
-----
I
G
T
E
T
Y
K
P
E
T
V
T
E
P
E
E
D
F
P
L
L
L
N
-----------
N
M
W
R
S
W
L
N
L
H
N
G
T
D
A
-
R
A
L
I
E
I
Y
N
D
T
Q
S
D
L
A
E
V
H
S
Q
F
A
T
GVLT
L
E
H
R
A
W
A
E
Q
T
S
L
R
---
I
Y
Y
E
L
---
N
R
--------
L
MSTKN
R
F
H
R
P
I
L
D
E
L
S
E
----------------------
R
L
A
D
K
F
F
V
N
F
S
L
F
Q
S
---------------
L
P
D
------
S
W
G
I
D
Q
V
F
P
V
L
P
L
S
G
L
Q
----
N
A
A
D
R
R
A
V
M
L
D
I
T
C
D
S
D
G
A
I
D
A
Y
V
D
G
Q
G
I
E
S
T
L
P
V
P
A
W
N
E
D
E
P
-----
Y
L
M
G
F
F
L
V
G
A
Y
Q
E
I
L
G
-----
D
M
H
N
L
F
G
D
T
H
S
--
V
V
V
N
V
G
D
Q
G
E
I
N
I
D
F
I
N
E
G
D
T
V
E
D
M
M
R
Y
V
H
----
I
D
V
D
Q
I
R
----
K
N
Y
H
S
L
V
S
Q
R
V
-
D
Q
E
-------
E
Q
Q
Q
I
L
A
E
L
E
Q
-
G
L
S
G
Y
T
Y
L
E
D
------------------------------------------------------------------------------------------------------------------
29
HHSearch
44.96
12%
-201
* C7 *
2N2H
-
SIN3A_MOUSE
B:
[668-710]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
A
L
Q
R
I
---
Y
A
D
K
A
A
-
D
I
I
D
G
L
R
K
N
P
S
I
A
V
P
I
V
L
K
R
L
---------
K
M
K
E
E
E
W
R
E
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
44.13
21%
10
- C5 -
4PG7
9
?
A:
[20-446]
-----------------------------------
H
M
K
K
L
N
I
A
L
L
--------------------------
G
L
G
T
----
V
G
S
G
V
V
K
I
I
E
E
N
--
R
Q
Q
I
Q
D
T
L
---------------
N
--
K
D
I
V
I
K
H
I
L
V
R
-----
D
K
S
K
K
R
P
L
N
------
I
S
Q
Y
H
L
T
E
D
V
N
E
---------------------
I
L
N
D
D
SLD
I
I
V
E
VMGGI
E
P
--
T
V
D
W
L
R
T
A
L
-
K
N
---
K
K
--
H
V
I
T
A
N
K
---
D
L
L
A
V
H
L
K
L
-
L
E
D
L
A
E
E
N
G
V
-------
A
L
K
F
E
A
S
V
A
G
G
P
N
N
I
S
K
F
M
G
I
L
N
G
T
S
N
F
I
L
S
K
M
T
K
E
Q
T
-------
T
F
E
E
A
L
D
E
A
K
--
R
L
G
-----
F
A
E
A
D
P
-
T
D
D
V
---
E
G
V
D
A
A
R
K
V
V
I
T
S
Y
L
S
F
N
Q
V
I
-------
K
L
N
D
V
K
R
R
G
I
S
G
V
T
--------
L
T
D
I
N
V
A
D
Q
L
G
Y
K
I
K
-
L
I
---------
G
K
G
I
Y
E
N
-----------
G
K
V
N
A
S
V
---
E
P
T
L
I
D
K
K
H
Q
L
A
A
------------------------------
V
-----------
E
D
E
Y
N
A
---
I
Y
V
I
G
D
-
A
V
G
D
T
M
F
Y
G
K
G
A
G
S
L
A
T
G
S
A
V
---------
V
S
D
L
L
N
V
A
L
F
---
F
E
S
T
L
---
P
P
--------
H
------
F
---
E
L
K
T
D
K
T
----------------------
R
E
M
E
K
S
N
F
F
V
-
V
V
N
H
---------------
V
K
---------------------------------------------
G
S
I
E
N
F
E
--
N
E
L
K
A
I
L
P
-----
F
H
R
S
L
R
V
A
N
Y
D
---------------------------
N
Q
S
--
Y
A
A
V
I
V
G
-------------------------------------------
L
E
S
-
S
P
-
E
E
L
-------
I
T
K
---
H
G
Y
---
E
V
D
K
V
Y
P
V
E
G
V
-----------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
42.44
23%
-168
- C7 -
3AZH
-
H31_HUMAN
A:
[52-130]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
E
I
R
-
R
Y
---
Q
K
S
T
E
L
L
I
R
K
L
---
P
F
Q
R
L
V
R
E
I
-
A
Q
D
F
K
T
D
L
R
-
F
Q
S
S
A
V
M
A
L
Q
E
A
C
E
A
Y
L
V
G
L
F
E
D
T
N
L
C
A
I
H
A
K
R
V
T
I
M
P
Q
D
I
Q
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
41.43
14%
21
* C8 *
4CR2
-
RPN1_YEAST
Z:
[49-993]
-------------
L
E
L
L
V
E
R
L
-----------
K
E
D
D
-
S
S
L
Y
E
A
S
L
N
-
A
L
K
E
S
I
K
N
S
T
S
S
M
T
A
VP
K
P
L
K
F
L
R
P
T
Y
P
----
D
L
C
S
I
Y
D
K
W
T
D
P
N
L
K
S
S
L
A
D
V
L
S
----
I
L
-
A
M
T
Y
SEN
G
--
K
H
D
S
L
R
Y
R
L
L
S
DV
S
D
F
E
G
W
G
H
E
Y
I
R
H
L
A
L
E
I
G
E
V
Y
N
D
Q
V
E
K
D
A
E
D
ETSSDGSKSDGSAATSGFE
F
S
K
E
D
-----
T
L
-----
R
L
--
C
L
D
I
V
P
Y
F
L
-
K
H
NG
E
E
D
A
V
D
L
L
L
E
I
E
S
I
D
K
L
P
Q
F
V
D
E
N
T
F
Q
R
V
C
Q
Y
M
V
A
C
V
P
L
L
P
P
P
E
D
V
A
F
L
K
T
A
Y
S
I
Y
L
S
Q
N
-
E
L
T
D
A
I
A
L
A
V
R
L
G
E
E
D
M
I
R
-------
S
V
F
D
A
T
S
D
P
V
--
M
H
K
Q
L
A
Y
I
L
A
A
Q
K
T
S
F
E
Y
E
GVQ
D
I
I
G
N
G
K
L
S
E
H
F
L
Y
L
A
K
E
L
N
L
T
G
----
P
K
V
P
E
D
I
Y
K
S
H
L
D
N
S
K
S
V
F
S
S
A
G
L
D
S
A
Q
Q
N
L
A
---
S
S
F
-
V
N
G
F
L
N
LGYCN
D
K
L
I
V
D
N
-----------
D
N
W
V
Y
K
T
---
K
G
D
G
M
T
S
A
V
A
S
I
G
S
I
Y
QWN
L
D
G
L
Q
------
Q
L
D
K
Y
L
Y
V
D
E
P
E
V
K
-----------
A
G
A
L
L
G
---
I
G
I
S
A
S
-
G
V
H
D
G
E
V
E
P
A
L
L
L
L
Q
D
Y
V
T
N
P
---------
D
T
K
I
S
S
A
A
I
L
---
G
L
G
I
A
---
F
A
GSKN
D
E
V
L
G
------
L
L
L
P
I
A
A
S
T
D
L
PIETAAM
A
S
L
A
L
A
H
V
F
VGTCN
G
D
I
T
T
S
I
M
D
N
F
-
L
E
R
T
AIELK
T
D
W
V
R
F
L
A
L
A
L
G
I
L
Y
MGQG
E
Q
V
D
D
V
L
------
E
T
I
S
A
I
EH
P
M
T
S
A
I
E
V
L
V
G
S
C
A
Y
T
G
T
G
D
V
L
L
I
--
Q
D
L
L
H
R
L
T
L
A
Y
A
V
L
G
I
A
L
I
A
L
G
E
D
I
G
K
E
M
S
L
R
H
F
G
H
L
M
H
Y
GN
E
H
I
R
R
M
V
P
-
L
A
M
--
G
I
V
S
V
S
D
P
Q
M
K
V
F
D
T
L
T
R
F
S
H
D
A
D
L
E
V
S
M
N
----
S
I
F
A
M
G
L
C
G
AG
T
N
N
A
R
L
A
Q
L
L
R
-
Q
L
A
-------
S
Y
Y
S
R
E
Q
D
A
L
F
I
T
R
L
A
Q
G
L
L
H
L
G
K
GTMTMDVFNDAHVLN
K
V
T
L
A
S
I
L
T
T
A
V
GLVSPSFMLKHHQLFYMLNAG
I
R
P
K
F
I
L
A
L
NDEG
E
P
I
K
V
N
V
R
V
G
QPVLLNHG
E
R
A
E
LETDEYISYTSHIEGV
V
I
L
K
K
NPDYREEE
8
PsiBlast_PDB
39.71
23%
-156
- C7 -
3AZJ
1
H31_HUMAN
A:
[52-130]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
E
I
R
-
R
Y
---
Q
K
S
T
E
L
L
I
R
K
L
---
P
F
Q
R
L
V
R
E
I
-
A
Q
D
F
K
T
D
L
R
-
F
Q
S
S
A
V
M
A
L
Q
E
A
C
E
A
Y
L
V
G
L
F
E
D
T
N
L
C
A
I
H
A
K
R
V
T
I
M
P
K
D
I
Q
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
39.46
23%
-145
- C7 -
3WKJ
1
H31_HUMAN
A:
[52-130]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
E
I
R
-
R
Y
---
Q
K
S
T
E
L
L
I
R
K
L
---
P
F
Q
R
L
V
R
E
I
-
A
Q
D
F
K
T
D
L
R
-
F
Q
S
S
A
V
M
A
L
Q
E
A
C
E
A
Y
L
V
G
L
F
E
D
T
N
L
C
A
I
H
A
K
R
V
T
I
M
P
K
D
I
Q
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
39.41
23%
-148
- C7 -
3AZF
1
H31_HUMAN
A:
[52-130]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
E
I
R
-
R
Y
---
Q
K
S
T
E
L
L
I
R
K
L
---
P
F
Q
R
L
V
R
E
I
-
A
Q
D
F
Q
T
D
L
R
-
F
Q
S
S
A
V
M
A
L
Q
E
A
C
E
A
Y
L
V
G
L
F
E
D
T
N
L
C
A
I
H
A
K
R
V
T
I
M
P
K
D
I
Q
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
39.39
23%
-164
- C7 -
3AZN
1
H31_HUMAN
A:
[52-130]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
E
I
R
-
R
Y
---
Q
K
S
T
E
L
L
I
R
K
L
---
P
F
Q
R
L
V
R
E
I
-
A
Q
D
F
K
T
D
L
R
-
F
Q
S
S
A
V
M
A
L
Q
E
A
C
E
A
Y
L
V
G
L
F
E
D
T
N
L
C
A
I
H
A
K
R
V
T
I
M
P
K
D
I
Q
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
39.10
23%
-150
- C7 -
3AZG
1
H31_HUMAN
A:
[52-130]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
E
I
R
-
R
Y
---
Q
K
S
T
E
L
L
I
R
K
L
---
P
F
Q
R
L
V
R
E
I
-
A
Q
D
F
K
T
D
L
R
-
F
Q
S
S
A
V
M
A
L
Q
E
A
C
E
A
Y
L
V
G
L
F
E
D
T
N
L
C
A
I
H
A
Q
R
V
T
I
M
P
K
D
I
Q
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
39.02
23%
-162
- C7 -
5CPI
-
?
A:
[48-126]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
E
I
R
-
R
Y
---
Q
K
S
T
E
L
L
I
R
K
L
---
P
F
Q
R
L
V
R
E
I
-
A
Q
D
F
K
T
D
L
R
-
F
Q
S
S
A
V
M
A
L
Q
E
A
C
E
A
Y
L
V
G
L
F
E
D
T
N
L
C
A
I
H
A
K
R
V
T
I
M
P
K
D
I
Q
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
38.99
23%
-155
- C7 -
3W97
-
H31_HUMAN
A:
[52-130]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
E
I
R
-
R
Y
---
Q
K
S
T
E
L
L
I
R
K
L
---
P
F
Q
R
L
V
R
E
I
-
A
Q
D
F
K
T
D
L
R
-
F
Q
S
S
A
V
M
A
L
Q
E
A
C
E
A
Y
L
V
G
L
F
E
D
T
N
L
C
A
I
H
A
K
R
V
T
I
M
P
K
D
I
Q
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
38.49
23%
-151
- C7 -
3W99
-
H31_HUMAN
A:
[52-130]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
E
I
R
-
R
Y
---
Q
K
S
T
E
L
L
I
R
K
L
---
P
F
Q
R
L
V
R
E
I
-
A
Q
D
F
K
T
D
L
R
-
F
Q
S
S
A
V
M
A
L
Q
E
A
C
E
A
Y
L
V
G
L
F
E
D
T
N
L
C
A
I
H
A
K
R
V
T
I
M
P
K
D
I
Q
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
38.35
23%
-125
- C7 -
3AZK
1
H31_HUMAN
A:
[52-130]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
E
I
R
-
R
Y
---
Q
K
S
T
E
L
L
I
R
K
L
---
P
F
Q
R
L
V
R
E
I
-
A
Q
D
F
K
T
D
L
R
-
F
Q
S
S
A
V
M
A
L
Q
E
A
C
E
A
Y
L
V
G
L
F
E
D
T
N
L
C
A
I
H
A
K
R
V
T
I
M
P
K
D
I
Q
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
38.28
23%
-150
- C7 -
3AZI
1
H31_HUMAN
A:
[52-130]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
E
I
R
-
R
Y
---
Q
K
S
T
E
L
L
I
R
K
L
---
P
F
Q
R
L
V
R
E
I
-
A
Q
D
F
K
T
D
L
R
-
F
Q
S
S
A
V
M
A
L
Q
E
A
C
E
A
Y
L
V
G
L
F
E
D
T
N
L
C
A
I
H
A
K
R
V
T
I
M
P
K
D
I
Q
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
37.87
23%
-148
- C7 -
3AZM
1
H31_HUMAN
A:
[52-130]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
E
I
R
-
R
Y
---
Q
K
S
T
E
L
L
I
R
K
L
---
P
F
Q
R
L
V
R
E
I
-
A
Q
D
F
K
T
D
L
R
-
F
Q
S
S
A
V
M
A
L
Q
E
A
C
E
A
Y
L
V
G
L
F
E
D
T
N
L
C
A
I
H
A
K
R
V
T
I
M
P
K
D
I
Q
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
37.81
23%
-152
- C7 -
3WAA
-
H31_HUMAN
A:
[48-126]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
E
I
R
-
R
Y
---
Q
K
S
T
E
L
L
I
R
K
L
---
P
F
Q
R
L
V
R
E
I
-
A
Q
D
F
K
T
D
L
R
-
F
Q
S
S
A
V
M
A
L
Q
E
A
C
E
A
Y
L
V
G
L
F
E
D
T
N
L
C
A
I
H
A
K
R
V
T
I
M
P
K
D
I
Q
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
37.81
23%
-137
- C7 -
3AFA
1
H31_HUMAN
A:
[52-130]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
E
I
R
-
R
Y
---
Q
K
S
T
E
L
L
I
R
K
L
---
P
F
Q
R
L
V
R
E
I
-
A
Q
D
F
K
T
D
L
R
-
F
Q
S
S
A
V
M
A
L
Q
E
A
C
E
A
Y
L
V
G
L
F
E
D
T
N
L
C
A
I
H
A
K
R
V
T
I
M
P
K
D
I
Q
L
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