@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu38540: (2016-08-04 )
MKMTNNTVLITGGSAGIGLELAKRLLELGNEVIICGRSEARLAEAKQQLPNIHTKQCDVADRSQREALYEWALKEYPNLNVLVNNAGIQKEIDFKKGTEELFVDGDEIELNFQAPVHLSALFTPHLMKQPEAAIVQVTSGLAFNPLAVYPVYCATKAALHSFSLTLRHQLRDTSVEVIEMAPPMVDTGLNQKSRDKQGLTYRGISSEEYVQYFLDGLKEGKQEITNERVEGLRDATRADYDRLFEQMNTQEN
Atome Classification :
(24 SA)
.........10........20........30.....---...40...----.----.----..----.-------50----.-----........-60........70.....-...80........--90.-..-.....100....-..-----.-.110.......120......-.---130.......140.-..-..--.--.150.......160.......170---.......180.......190..---------..-------------.-----------..200.......210.......220......-.230.......240.......250
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MKMTN
N
T
V
L
I
TGGSAGI
G
L
E
L
A
K
R
L
L
E
LGN
E
V
I
I
CG---RSE
A
R
L
A
E
----
A
----
K
----
Q
Q----L-------P-----N-----IHTKQCDV-A
D
R
S
Q
R
E
A
L
Y
E
W
A
L
K
EY-PN
L
N
V
L
V
NNAGIQ--KEI-DF-KKG
T
E
E
-
L
F
VDG-
D
E
-----
I
-
E
L
N
FQA
P
V
H
L
S
A
LF
T
P
H
L
MK-Q---PE
A
A
I
V
Q
VTSGLAF-NP-
L
A
--
V
--
Y
P
V
Y
C
A
T
K
A
A
L
H
S
F
S
L
T
L
R
H
QLRD---T
S
V
E
V
I
EMAP
P
M
V
DTGLNQKSR---------DK-------------Q-----------G
L
T
YRGI
S
S
E
E
Y
V
Q
Y
F
L
D
G
L
K
E
G
K
Q
E
I
T
N
E
R
-
V
E
G
L
R
D
A
T
R
A
D
Y
D
R
L
F
E
Q
MNTQEN
1
PsiBlast_PDB
83.34
33%
0
- C- -
3ASU
-
?
A:
[3-202]
-------
V
L
V
T
G
A
T
A
G
F
G
E
C
I
T
R
R
F
I
Q
Q
G
H
K
V
I
A
T
G
---
R
R
Q
E
R
L
Q
E
----
L
----
K
----
D
E
----
L
G------
D
-----
N
-----
L
Y
I
A
Q
L
D
V
-
R
N
R
A
A
I
E
E
M
L
A
S
L
P
A
E
W
-
C
N
I
D
I
L
V
N
N
A
G
L
A
L
G
M
E
P
-
A
H
-
K
A
S
V
E
D
-
W
E
T
----
M
-----
I
-
D
T
N
N
K
G
L
V
Y
M
T
R
A
V
L
P
G
M
V
E
-
R
---
N
H
G
H
I
I
N
I
G
S
T
A
G
S
-
W
P
-
Y
A
--
G
--
G
N
V
Y
G
A
T
K
A
F
V
R
Q
F
S
L
N
L
R
T
D
L
H
G
---
T
A
V
R
V
T
D
I
E
P
G
L
V
-----------------------------------------------------------------------------------------------------
31
HHSearch
82.04
24%
-101
- C1 -
3GED
4
?
A:
[2-215]
----
N
R
G
V
I
V
T
G
G
G
H
G
I
G
K
Q
I
C
L
D
F
L
E
A
G
D
K
V
C
F
I
D
---
I
D
E
K
R
S
A
D
----
F
----
A
----
K
E
----
R
-------
P
-----
N
-----
L
F
Y
F
H
G
D
V
-
A
D
P
L
T
L
K
K
F
V
E
Y
A
M
E
K
L
-
Q
R
I
D
V
L
V
N
N
A
C
R
G
--
S
K
G
-
I
L
-
S
-
S
L
-
L
-
Y
E
E
F
D
-
Y
I
-----
L
-
S
V
G
L
K
A
P
Y
E
L
S
R
L
C
R
D
E
L
I
K
-----
N
K
G
R
I
I
N
I
A
S
T
R
A
F
-
Q
S
-
E
P
--
D
--
S
E
A
Y
A
S
A
K
G
G
I
V
A
L
T
H
A
L
A
M
S
L
G
P
----
D
V
L
V
N
C
I
A
P
G
W
I
N
V
T
---
E
F
T
---------
Q
E
D
C
A
----------
A
-----------
I
P
A
G
K
V
G
T
P
K
D
I
S
N
M
V
L
F
L
C
Q
Q
----------------------------------
36
HHSearch
80.61
23%
-119
- C1 -
1O5I
-
?
A:
[16-229]
-
G
I
R
D
K
G
V
L
V
L
A
A
S
R
G
I
G
R
A
V
A
D
V
L
S
Q
E
G
A
E
V
T
I
C
A
---
R
N
E
E
L
L
K
R
----------------------------
S
-----
G
-----
H
R
Y
V
V
C
D
L
-
R
K
D
--
L
D
L
L
F
----
E
K
V
-
K
E
V
D
I
L
V
L
N
A
G
G
P
--
K
A
G
-
F
F
-
D
-
E
L
-
T
-
N
E
D
F
K
-
E
A
-----
I
-
D
S
L
F
L
N
M
I
K
I
V
R
N
Y
L
P
A
M
K
E
-
K
---
G
W
G
R
I
V
A
I
T
S
F
S
V
I
-
S
P
-
I
E
--
N
--
L
Y
T
S
N
S
A
R
M
A
L
T
G
F
L
K
T
L
S
F
E
V
A
P
---
Y
G
I
T
V
N
C
V
A
P
G
W
T
E
T
E
R
V
K
E
L
L
---------
S
E
E
K
K
K
Q
V
E
S
-----
Q
-----------
I
P
M
R
R
M
A
K
P
E
E
I
A
S
V
V
A
F
L
C
S
E
K
---------------------------------
34
HHSearch
78.14
22%
-74
- C1 -
2AG5
2
BDH2_HUMAN
A:
[3-229]
-
R
L
D
G
K
V
I
I
L
T
A
A
A
Q
G
I
G
Q
A
A
A
L
A
F
A
R
E
G
A
K
V
I
A
T
D
---
I
N
E
S
K
L
Q
E
----
L
----
E
----
K
-----
Y
-------
P
-----
G
-----
I
Q
T
R
V
L
D
V
-
T
K
K
K
Q
I
D
Q
F
A
N
E
----
V
-
E
R
L
D
V
L
F
N
V
A
G
F
V
--
H
H
G
-
T
V
-
L
-
D
C
-
E
-
E
K
D
W
D
-
F
S
-----
M
-
N
L
N
V
R
S
M
Y
L
M
I
K
A
F
L
P
K
M
L
A
-
Q
---
K
S
G
N
I
I
N
M
S
S
V
A
S
S
V
K
G
-
V
V
--
N
--
R
C
V
Y
S
T
T
K
A
A
V
I
G
L
T
K
S
V
A
A
D
F
I
Q
---
Q
G
I
R
C
N
C
V
C
P
G
T
V
D
T
P
S
L
Q
E
R
I
---------
Q
A
RGN
P
E
E
A
R
N
D
F
L
K
R
-----------
Q
K
T
G
R
F
A
T
A
E
E
I
A
M
L
C
V
Y
L
A
S
D
E
S
--------------------------------
15
PsiBlast_PDB
77.07
26%
-107
- C1 -
4NBU
1
?
A:
[10-195]
-
R
L
Q
D
K
V
A
I
I
T
G
A
A
N
G
I
G
L
E
A
A
R
V
F
M
K
E
G
A
K
V
V
I
A
D
---
F
N
E
A
A
G
K
E
----
A
----
V
----
E
A
----
N
-------
P
-----
G
-----
V
V
F
I
R
V
D
V
-
S
D
R
E
S
V
H
R
L
V
E
N
V
A
E
R
F
-
G
K
I
D
I
L
I
N
N
A
G
I
T
--
R
D
S
-
M
L
-
S
K
M
T
V
D
-
Q
F
--
Q
-
Q
V
-----
I
-
N
V
N
L
T
G
V
F
H
C
T
Q
A
V
L
P
Y
M
A
E
-
Q
---
G
K
G
K
I
I
N
T
S
S
V
T
G
T
-
Y
G
-
N
V
--
G
--
Q
T
N
Y
A
A
A
K
A
G
V
I
G
M
T
K
T
W
A
K
E
L
A
R
---
K
G
I
N
V
N
A
V
A
P
G
F
T
E
T
A
M
-------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
76.66
30%
-27
- C- -
4IUY
-
?
A:
[11-199]
-------
I
L
I
T
G
A
S
S
G
L
G
H
H
I
A
E
L
F
A
K
E
G
A
N
I
V
I
C
A
---
R
R
L
E
R
L
K
E
----
L
----
E
----
S
H
----
I
-------
K
-----
N
E
YG
V
Q
V
Y
T
F
A
L
D
V
-
N
D
R
S
A
V
K
D
M
L
S
S
L
E
A
E
G
-
V
T
I
D
V
L
I
N
N
A
G
V
S
--
D
T
K
-
R
F
-
L
D
Y
N
D
E
----
D
W
-
D
K
-----
I
V
D
T
N
L
K
A
P
W
Q
C
A
Q
E
V
V
Q
H
M
I
K
A
E
---
R
K
G
S
I
I
N
I
T
S
I
L
S
Q
-
S
T
N
L
G
--
V
--
S
P
-
Y
C
A
S
K
A
G
L
R
H
L
T
E
V
M
A
V
E
L
A
R
---
F
G
I
N
V
N
A
I
A
P
G
Y
M
I
T
E
I
N
E
E
----------------------------------------------------------------------------------------------
14
PsiBlast_PDB
75.54
25%
-56
- C1 -
3O4R
3
DHRS4_HUMAN
A:
[13-204]
--
L
A
N
K
V
A
L
V
T
A
S
T
D
G
I
G
F
A
I
A
R
R
L
A
Q
D
G
A
H
V
V
V
S
S
---
R
K
Q
Q
N
V
D
Q
----
A
----
V
----
A
T
----
L
-------
Q
G
E
GL-
S
-----
V
T
G
T
V
C
H
V
-
G
K
A
E
D
R
E
R
L
V
A
T
A
V
K
L
H
-
G
G
I
D
I
L
V
S
N
A
A
V
N
--
P
F
F
G
S
I
-
M
D
V
T
E
E
-
V
W
--
D
-
K
T
-----
L
-
D
I
N
V
K
A
P
A
L
M
T
K
A
V
V
P
E
M
E
K
-
R
---
G
G
G
S
V
V
I
V
S
S
I
A
A
F
-
S
P
-
S
P
--
G
--
F
S
P
Y
N
V
S
K
T
A
L
L
G
L
T
K
T
L
A
I
E
L
A
P
---
R
N
I
R
V
N
C
L
A
P
G
L
I
K
T
S
F
S
R
-----------------------------------------------------------------------------------------------
19
PsiBlast_PDB
75.30
29%
-50
- C1 -
3AI1
-
?
A:
[3-192]
M
G
I
S
G
K
V
A
V
I
T
G
S
S
S
G
I
G
L
A
I
A
E
G
F
A
K
E
G
A
H
I
V
L
V
A
---
R
Q
V
D
R
L
H
E
----
A
----
A
----
R
S
----
L
-------
K
E
K
F
G
V
R
-----
V
L
E
V
A
V
D
V
-
A
T
P
E
G
V
D
A
V
V
E
S
V
R
S
S
F
-
G
G
A
D
I
L
V
N
N
A
G
------------
T
G
S
N
E
-
T
I
M
E
A
A
D
E
K
W
Q
F
Y
W
-
E
L
H
V
M
A
A
V
R
L
A
R
G
L
V
P
G
M
R
A
-
R
---
G
G
G
A
I
I
H
N
A
S
I
C
A
V
-
Q
P
-
L
W
--
Y
--
E
P
I
Y
N
V
T
K
A
A
L
M
M
F
S
K
T
L
A
T
E
V
I
K
---
D
N
I
R
V
N
C
I
N
P
G
L
I
L
T
---------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
75.27
30%
-51
- C1 -
2AE2
2
TRN2_DATST
A:
[11-196]
------
T
A
L
V
T
G
G
S
R
G
I
G
Y
G
I
V
E
E
L
A
S
L
G
A
S
V
Y
T
C
S
---
R
N
Q
K
E
L
N
D
----
C
----
L
----
T
Q
----
W
-------
R
-----
S
K
GFK-
V
E
A
S
V
C
D
L
-
S
S
R
S
E
R
Q
E
L
M
N
T
V
A
N
H
F
H
G
K
L
N
I
L
V
N
N
A
G
I
-----
V
-
I
Y
-
K
E
A
K
D
Y
-
T
V
E
D
Y
-
S
L
-----
I
M
S
I
N
F
E
A
A
Y
H
L
S
V
L
A
H
P
F
L
K
A
-
S
---
E
R
G
N
V
V
F
I
S
S
V
S
G
A
-
L
A
-
V
P
--
Y
--
E
A
V
Y
G
A
T
K
G
A
M
D
Q
L
T
R
C
L
A
F
E
W
A
K
---
D
N
I
R
V
N
G
V
G
P
G
V
I
A
T
S
L
-------------------------------------------------------------------------------------------------
48
HHSearch
74.40
24%
-43
- C1 -
1YB1
6
DHB11_HUMAN
A:
[28-268]
-
S
V
T
G
E
I
V
L
I
T
G
A
G
H
G
I
G
R
L
T
A
Y
E
F
A
K
L
K
S
K
L
V
L
W
D
---
I
N
K
H
G
L
E
E
----
T
----
A
----
A
K
C
K
G
L
G
-------
A
-----
K
-----
V
H
T
F
V
V
D
C
-
S
N
R
E
D
I
Y
S
S
A
K
K
V
K
A
E
I
-
G
D
V
S
I
L
V
N
N
A
G
V
V
--
Y
T
S
-
D
L
-
F
-
A
T
-
Q
-
D
P
Q
I
E
-
K
T
-----
F
-
E
V
N
V
L
A
H
F
W
T
T
K
A
F
L
P
A
M
T
K
-
N
---
N
H
G
H
I
V
T
V
A
S
A
A
-
H
-
V
S
-
V
P
--
F
--
L
L
A
Y
C
S
S
K
F
A
A
V
G
F
H
K
T
L
T
D
E
L
A
A
L
QI
T
G
V
K
T
T
C
L
C
P
N
F
V
N
T
G
F
I
K
N
P
S
---------
T
S
---------------------------
L
G
P
T
L
E
P
E
E
V
V
N
R
L
M
H
G
I
L
T
E
Q
K
M
I
F
I
P
S
S
I
A
F
L
T
T
L
E
R
I
L
-------------
37
HHSearch
73.89
21%
-35
- C1 -
4G81
2
?
D:
[6-235]
-
D
L
T
G
K
T
A
L
V
T
G
S
A
R
G
L
G
F
A
Y
A
E
G
L
A
A
A
G
A
R
V
I
L
N
D
---
I
R
A
T
L
L
A
E
----
S
----
V
DTLT
R
K
----
G
-------
Y
-----
D
-----
A
H
G
V
A
F
D
V
-
T
D
E
L
A
I
E
A
A
F
S
K
L
D
A
E
G
-
I
H
V
D
I
L
I
N
N
A
G
I
Q
--
Y
R
K
-
P
M
-
V
-
E
L
-
E
-
L
E
N
W
Q
-
K
V
-----
I
-
D
T
N
L
T
S
A
F
L
V
S
R
S
A
A
K
R
M
I
A
-
R
N--
S
G
G
K
I
I
N
I
G
S
L
T
S
Q
-
A
A
-
R
P
--
T
--
V
A
P
Y
T
A
A
K
G
G
I
K
M
L
T
C
S
M
A
A
E
W
A
Q
---
F
N
I
Q
T
N
A
I
G
P
G
Y
I
L
T
D
M
N
T
A
L
I
---------
E
D
-------------
K
QFDSWVKSS--
T
P
S
Q
R
W
G
R
P
E
E
L
I
G
T
A
I
F
L
S
S
K
----------------------------------
7
PsiBlast_PDB
73.72
30%
-51
- C1 -
1IPF
2
TRN2_DATST
A:
[10-195]
------
T
A
L
V
T
G
G
S
R
G
I
G
Y
G
I
V
E
E
L
A
S
L
G
A
S
V
Y
T
C
S
---
R
N
Q
K
E
L
N
D
----
C
----
L
----
T
Q
----
W
-------
R
-----
S
K
GFK-
V
E
A
S
V
C
D
L
-
S
S
R
S
E
R
Q
E
L
M
N
T
V
A
N
H
F
H
G
K
L
N
I
L
V
N
N
A
G
I
-----
V
-
I
Y
-
K
E
A
K
D
Y
-
T
V
E
D
Y
-
S
L
-----
I
M
S
I
N
F
E
A
A
Y
H
L
S
V
L
A
H
P
F
L
K
A
-
S
---
E
R
G
N
V
V
F
I
S
S
V
S
G
A
-
L
A
-
V
P
--
Y
--
E
A
V
Y
G
A
T
K
G
A
M
D
Q
L
T
R
C
L
A
F
E
W
A
K
---
D
N
I
R
V
N
G
V
G
P
G
V
I
A
T
S
L
-------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
73.09
30%
-10
- C1 -
1XHL
2
?
A:
[23-217]
-
R
F
S
G
K
S
V
I
I
T
G
S
S
N
G
I
G
R
S
A
A
V
I
F
A
K
E
G
A
Q
V
T
I
T
G
---
R
N
E
D
R
L
E
E
----
T
----
K
----
Q
Q
----
I
L
K
A
GVPA
E
-----
K
-----
I
N
A
V
V
A
D
V
-
T
E
A
S
G
Q
D
D
I
I
N
T
T
L
A
K
F
-
G
K
I
D
I
L
V
N
N
A
G
A
N
--
L
A
D
-
G
T
-
A
N
T
D
Q
P
-
V
E
L
Y
Q
-
K
T
-----
F
-
K
L
N
F
Q
A
V
I
E
M
T
Q
K
T
K
E
H
L
I
K
-
T
----
K
G
E
I
V
N
V
S
S
I
V
A
--
G
P
-
Q
A
HS
G
--
Y
P
Y
Y
A
C
A
K
A
A
L
D
Q
Y
T
R
C
T
A
I
D
L
I
Q
---
H
G
V
R
V
N
S
V
S
P
G
A
V
A
T
G
F
-------------------------------------------------------------------------------------------------
56
Fugue
72.85
24%
3
- C1 -
1A4U
-
ADH_DROLE
A:
[1-254]
M
D
L
T
N
K
N
V
I
F
V
A
A
L
G
G
I
G
L
D
T
S
R
E
L
V
K
R
N
L
K
N
F
V
I
L
D
RV
E
N
P
T
A
L
A
E
----
L
----
K
----
A
I
----
N
-------
P
KV---
N
-----
I
T
F
H
T
Y
D
V
T
V
P
V
A
E
S
K
K
L
L
K
K
I
F
D
Q
L
-
K
T
V
D
I
L
I
N
G
A
G
I
L
--
D
D
H
-
Q
------------
I
E
-
R
T
-----
I
-
A
I
N
F
T
G
L
V
N
T
T
T
A
I
L
D
F
W
D
K
-
R
KGG
P
G
G
I
I
A
N
I
C
S
V
T
G
F
-
N
A
-
I
H
--
Q
--
V
P
V
Y
S
A
S
K
A
A
V
V
S
F
T
N
S
L
A
K
L
A
P
I
---
T
G
V
T
A
Y
S
I
N
P
G
I
T
R
T
P
L
V
H
T
F
N
S
WLDVEPR
V
A
E
-------------
L
-----------
L
L
S
H
P
T
Q
T
S
E
Q
C
G
Q
N
F
V
K
A
I
E
A
N
K
----
N
G
A
-
I
W
K
L
D
L
G
T
L
E
A
I
E
W
T
K
H
W
D
S
H
I
--
6
PsiBlast_PDB
72.65
30%
-48
- C1 -
1IPE
1
TRN2_DATST
A:
[10-195]
------
T
A
L
V
T
G
G
S
R
G
I
G
Y
G
I
V
E
E
L
A
S
L
G
A
S
V
Y
T
C
S
---
R
N
Q
K
E
L
N
D
----
C
----
L
----
T
Q
----
W
-------
R
-----
S
K
GFK-
V
E
A
S
V
C
D
L
-
S
S
R
S
E
R
Q
E
L
M
N
T
V
A
N
H
F
H
G
K
L
N
I
L
V
N
N
A
G
I
-----
V
-
I
Y
-
K
E
A
K
D
Y
-
T
V
E
D
Y
-
S
L
-----
I
M
S
I
N
F
E
A
A
Y
H
L
S
V
L
A
H
P
F
L
K
A
-
S
---
E
R
G
N
V
V
F
I
S
S
V
S
G
A
-
L
A
-
V
P
--
Y
--
E
A
V
Y
G
A
T
K
G
A
M
D
Q
L
T
R
C
L
A
F
E
W
A
K
---
D
N
I
R
V
N
G
V
G
P
G
V
I
A
T
S
L
-------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
72.49
29%
-49
- C1 -
3AI2
1
?
A:
[3-192]
M
G
I
S
G
K
V
A
V
I
T
G
S
S
S
G
I
G
L
A
I
A
E
G
F
A
K
E
G
A
H
I
V
L
V
A
---
R
Q
V
D
R
L
H
E
----
A
----
A
----
R
S
----
L
-------
K
E
K
FG
V
R
-----
V
L
E
V
A
V
D
V
-
A
T
P
E
G
V
D
A
V
V
E
S
V
R
S
S
F
-
G
G
A
D
I
L
V
N
N
A
G
------------
T
G
S
N
E
-
T
I
M
E
A
A
D
E
K
W
Q
F
Y
W
-
E
L
H
V
M
A
A
V
R
L
A
R
G
L
V
P
G
M
R
A
-
R
---
G
G
G
A
I
I
H
N
A
S
I
C
A
V
-
Q
P
-
L
W
--
Y
--
E
P
I
Y
N
V
T
K
A
A
L
M
M
F
S
K
T
L
A
T
E
V
I
K
---
D
N
I
R
V
N
C
I
N
P
G
L
I
L
T
---------------------------------------------------------------------------------------------------
50
HHSearch
72.05
18%
-46
- C1 -
3WDS
2
?
A:
[9-245]
-
D
L
S
G
R
K
A
I
V
T
G
G
S
K
G
I
G
A
A
I
A
R
A
L
D
K
A
G
A
T
V
A
I
A
D
---
L
D
V
M
A
A
Q
A
----
V
----
V
----
A
G
----
L
E------
N
-----
G
-----
G
F
A
V
E
V
D
V
-
T
K
R
A
S
V
D
A
A
M
Q
K
A
I
D
A
L
-
G
G
F
D
L
L
C
A
N
A
G
V
S
--
T
M
R
-
P
A
-
V
-
D
I
-
T
-
D
E
E
W
D
-
F
N
-----
F
-
D
V
N
A
R
G
V
F
L
A
N
Q
I
A
C
R
H
F
L
A
-
S
N--
T
K
G
V
I
V
N
T
A
S
L
A
A
K
-
V
G
-
A
P
--
L
--
L
A
H
Y
S
A
S
K
F
A
V
F
G
W
T
Q
A
L
A
R
E
M
A
P
---
K
N
I
R
V
N
C
V
C
P
G
F
V
K
T
A
M
Q
E
R
E
I
---------
I
W
E
A
E
L
R
GMT
P
----
E
A
V
R
A
E
Y
V
S
L
--
T
P
L
G
R
I
E
E
P
E
D
V
A
D
V
V
V
F
L
A
S
D
A
---------------------------------
11
PsiBlast_PDB
71.43
30%
-22
- C1 -
1XKQ
1
?
A:
[3-199]
-
R
F
S
N
K
T
V
I
I
T
G
S
S
N
G
I
G
R
T
T
A
I
L
F
A
Q
E
G
A
N
V
T
I
T
G
---
R
S
S
E
R
L
E
E
----
T
----
R
----
Q
I
----
I
L
K
S
GVSE
K
-----
Q
-----
V
N
S
V
V
A
D
V
-
T
T
E
D
G
Q
D
Q
I
I
N
S
T
L
K
Q
F
-
G
K
I
D
V
L
V
N
N
A
G
A
A
--
I
P
D
-
A
F
G
T
T
G
T
D
Q
G
I
D
I
Y
H
-
K
T
-----
L
-
K
L
N
L
Q
A
V
I
E
M
T
K
K
V
K
P
H
L
V
A
-
S
----
K
G
E
I
V
N
V
S
S
I
V
A
--
G
P
-
Q
A
--
Q
PD
F
L
Y
Y
A
I
A
K
A
A
L
D
Q
Y
T
R
S
T
A
I
D
L
A
K
---
F
G
I
R
V
N
S
V
S
P
G
M
V
E
T
G
F
-------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
71.33
27%
-58
- C1 -
4NBV
1
?
A:
[1-198]
M
K
L
Q
G
R
V
A
I
I
T
G
A
A
A
G
I
G
F
A
T
A
Q
R
F
A
E
D
G
A
I
V
V
L
C
D
---
V
Q
E
A
R
V
R
E
A
A
A
R
L
----
A
----
A
T
----
G
-------
A
-----
T
-----
V
S
A
Y
R
V
D
V
-
T
R
R
D
E
V
D
A
M
V
A
A
V
L
A
A
H
-
Q
R
V
D
I
L
V
N
N
A
G
I
T
--
K
D
A
-
R
L
-
A
K
M
T
E
A
-
Q
F
--
D
-
A
V
-----
I
-
D
V
N
L
K
G
V
F
N
C
A
Q
A
V
A
G
L
M
T
E
-
Q
---
G
K
G
V
I
L
N
A
S
S
V
V
G
L
-
Y
G
-
N
F
--
G
--
Q
T
N
Y
A
A
S
K
F
G
V
I
G
F
T
K
T
W
A
R
E
L
G
P
---
K
G
V
R
V
N
A
V
C
P
G
F
V
N
T
E
I
L
Q
T
V
P
---------
D
K
---------------------------------------------------------------------------------
43
HHSearch
71.09
20%
-35
- C1 -
4FN4
3
?
A:
[4-236]
-
S
L
K
N
K
V
V
I
V
T
G
A
G
S
G
I
G
R
A
I
A
K
K
F
A
L
N
D
S
I
V
V
A
V
E
---
L
L
E
D
R
L
N
Q
----
I
----
V
----
Q
E
L
R
G
M
G
-------
K
-----
E
-----
V
L
G
V
K
A
D
V
-
S
K
K
K
D
V
E
E
F
V
R
R
T
F
E
T
Y
-
S
R
I
D
V
L
C
N
N
A
G
I
M
--
D
G
V
-
T
P
-
V
A
E
V
-
S
-
D
E
L
W
E
-
R
V
-----
L
-
A
V
N
L
Y
S
A
F
Y
S
S
R
A
V
I
P
I
M
L
K
-
Q
---
G
K
G
V
I
V
N
T
A
S
I
A
G
I
-
R
G
-
G
F
--
A
--
G
A
P
Y
T
V
A
K
H
G
L
I
G
L
T
R
S
I
A
A
H
Y
G
D
---
Q
G
I
R
A
V
A
V
L
P
G
T
V
K
T
N
I
G
L
G
S
S
---------
K
P
-------------
S
E
L
G
M
R
T
L
T
K
L
M
S
L
S
S
R
L
A
E
P
E
D
I
A
N
V
I
V
F
L
A
S
D
E
---------------------------------
27
PsiBlast_CBE
60.63
35%
-41
- C1 -
3LF2
2
?
C:
[6-162]
--
L
S
E
A
V
A
V
V
T
G
G
S
S
G
I
G
L
A
T
V
E
L
L
L
E
A
G
A
A
V
A
F
C
A
---
R
D
G
E
R
L
R
A
----
A
E
S
A
L
R
----
Q
R
----
F
-------
P
-----
G
AR---
L
F
A
S
V
C
D
V
-
L
D
A
L
Q
V
R
A
F
A
E
A
C
E
R
T
L
-
G
C
A
S
I
L
V
N
N
A
G
Q
G
--
R
V
S
-
T
F
-
A
E
T
T
D
E
-
A
W
--
S
-
E
E
-----
L
-
Q
L
K
F
F
S
V
I
H
P
V
R
A
F
L
P
Q
L
E
S
-
R
---
A
D
A
A
I
V
C
V
N
S
L
L
A
S
-
Q
P
--------
E
P
H
M
V
A
T
S
A
A
-----------------------------------------------------------------------------------------------------------------------------------
28
PsiBlast_CBE
60.37
35%
-39
- C1 -
3LF2
2
?
B:
[6-162]
--
L
S
E
A
V
A
V
V
T
G
G
S
S
G
I
G
L
A
T
V
E
L
L
L
E
A
G
A
A
V
A
F
C
A
---
R
D
G
E
R
L
R
A
----
A
E
S
A
L
R
----
Q
R
----
F
-------
P
-----
G
AR---
L
F
A
S
V
C
D
V
-
L
D
A
L
Q
V
R
A
F
A
E
A
C
E
R
T
L
-
G
C
A
S
I
L
V
N
N
A
G
Q
G
--
R
V
S
-
T
F
-
A
E
T
T
D
E
-
A
W
--
S
-
E
E
-----
L
-
Q
L
K
F
F
S
V
I
H
P
V
R
A
F
L
P
Q
L
E
S
-
R
---
A
D
A
A
I
V
C
V
N
S
L
L
A
S
-
Q
P
--------
E
P
H
M
V
A
T
S
A
A
-----------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
59.78
35%
-34
- C1 -
3LF2
2
?
A:
[6-168]
--
L
S
E
A
V
A
V
V
T
G
G
S
S
G
I
G
L
A
T
V
E
L
L
L
E
A
G
A
A
V
A
F
C
A
---
R
D
G
E
R
L
R
A
----
A
E
S
A
L
R
----
Q
R
----
F
-------
P
-----
G
AR---
L
F
A
S
V
C
D
V
-
L
D
A
L
Q
V
R
A
F
A
E
A
C
E
R
T
L
-
G
C
A
S
I
L
V
N
N
A
G
Q
G
--
R
V
S
-
T
F
-
A
E
T
T
D
E
-
A
W
--
S
-
E
E
-----
L
-
Q
L
K
F
F
S
V
I
H
P
V
R
A
F
L
P
Q
L
E
S
-
R
---
A
D
A
A
I
V
C
V
N
S
L
L
A
S
-
Q
P
--------
E
P
H
M
V
A
T
S
A
A
-----------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
58.64
35%
-38
- C1 -
3LF2
3
?
D:
[6-162]
--
L
S
E
A
V
A
V
V
T
G
G
S
S
G
I
G
L
A
T
V
E
L
L
L
E
A
G
A
A
V
A
F
C
A
---
R
D
G
E
R
L
R
A
----
A
ESAL
R
----
Q
R
----
F
-------
P
-----
G
AR---
L
F
A
S
V
C
D
V
-
L
D
A
L
Q
V
R
A
F
A
E
A
C
E
R
T
L
-
G
C
A
S
I
L
V
N
N
A
G
Q
G
--
R
V
S
-
T
F
-
A
E
T
T
D
E
-
A
W
--
S
-
E
E
-----
L
-
Q
L
K
F
F
S
V
I
H
P
V
R
A
F
L
P
Q
L
E
S
-
R
---
A
D
A
A
I
V
C
V
N
S
L
L
A
S
-
Q
P
--------
E
P
H
M
V
A
T
S
A
A
-----------------------------------------------------------------------------------------------------------------------------------