@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu40550: (2016-08-07 )
MEKILIFGHQNPDTDTICSAIAYADLKNKLGFNAEPVRLGQVNGETQYALDYFKQESPRLVETAANEVNGVILVDHNERQQSIKDIEEVQVLEVIDHHRIANFETAEPLYYRAEPVGCTATILNKMYKENNVKIEKEIAGLMLSAIISDSLLFKSPTCTDQDVAAAKELAEIAGVDAEEYGLNMLKAGADLSKKTVEELISLDAKEFTLGSKKVEIAQVNTVDIEDVKKRQAELEAVISKVVAEKNLDLFLLVITDILENDSLALAIGNEAAKVEKAFNVTLENNTALLKGVVSRKKQVVPVLTDAMAE
Atome Classification :
(21 SA)
.........10........20.....-...-30........40........50........60..-....-..70........80........90........100.......110.......120.......130.......140-.......150.......160.......170......-.180.......190.......200.......210.......220.......230.......240.......250.......--260.......270........280--.......290.......300.......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
E
K
I
L
I
F
GHQNP
D
T
D
T
I
C
S
A
I
A
Y
A
D
L
-
K
N
K-LGFNAEP
V
R
L
GQVNGE
T
Q
Y
A
L
D
Y
F
KQESP
R
L
V
E
T
-AANE-V
N
G
V
I
L
VD
H
N
E
R
Q
Q
S
I
K
D
I
E
E
V
Q
V
L
E
V
I
D
H
HRIANFETAE
P
L
Y
Y
RAEPVG
C
T
A
T
I
L
N
K
M
Y
K
ENNV
K
I
E
K
E
I
A
G
L
M
-
L
S
A
I
ISDS
L
L
FKSPTCT
D
Q
D
V
A
A
A
K
E
L
A
E
I
AGV
D
A
E
-
E
Y
G
L
N
M
L
KAGAD
L
S
K
K
T
V
E
E
L
I
SL
D
A
K
EFTLGS
K
K
V
E
I
A
Q
V
N
T
V
D
I
E
D
V
K
K
R
Q
A
E
L
E
A
V
I
S
K
V
V
A
EKNL
D
L
F
L
L
V
I
T
D
I
LE--ND
S
L
A
L
A
IGN
E
A
-
A
K
V
E
K
A
F
N
V
T
L--EN
N
T
A
L
L
K
G
V
V
SRKKQ
V
V
P
V
L
T
D
AMAE
4
PsiBlast_PDB
91.61
98%
-119
- C1 -
1K23
2
PPAC_BACSU
A:
[2-307]
-
E
K
I
L
I
F
G
H
Q
N
P
D
T
D
T
I
C
S
A
I
A
Y
A
D
L
-
K
N
K
-
L
G
F
N
A
E
P
V
R
L
G
Q
V
N
G
E
T
Q
Y
A
L
D
Y
F
K
Q
E
S
P
R
L
V
E
T
-
A
A
N
E
-
V
N
G
V
I
L
V
D
H
N
E
R
Q
Q
S
I
K
D
I
E
E
V
Q
V
L
E
V
I
D
H
H
R
I
A
N
F
E
T
A
E
P
L
Y
Y
R
A
E
P
V
G
C
T
A
T
I
L
N
K
M
Y
K
E
N
N
V
K
I
E
K
E
I
A
G
L
M
-
L
S
A
I
I
S
D
S
L
L
F
K
S
P
T
C
T
D
Q
D
V
A
A
A
K
E
L
A
E
I
A
G
V
D
A
E
-
E
Y
G
L
N
M
L
K
A
G
A
D
L
S
K
K
T
V
E
E
L
I
S
L
D
A
K
E
F
T
L
G
S
K
K
V
E
I
A
Q
V
N
T
V
D
I
E
D
V
K
K
R
Q
A
E
L
E
A
V
I
S
K
V
V
A
E
K
N
L
D
L
F
L
L
V
I
T
D
I
L
E
--
N
D
S
L
A
L
A
I
G
N
E
A
-
A
K
V
E
K
A
F
N
V
T
L
--
E
N
N
T
A
L
L
K
G
V
V
S
R
K
K
Q
V
V
P
V
L
T
D
A
M
--
2
PsiBlast_PDB
89.08
100%
-98
- C1 -
2HAW
9
PPAC_BACSU
A:
[2-308]
-
E
K
I
L
I
F
G
H
Q
N
P
D
T
D
T
I
C
S
A
I
A
Y
A
D
L
-
K
N
K
-
L
G
F
N
A
E
P
V
R
L
G
Q
V
N
G
E
T
Q
Y
A
L
D
Y
F
K
Q
E
S
P
R
L
V
E
T
-
A
A
N
E
-
V
N
G
V
I
L
V
D
H
N
E
R
Q
Q
S
I
K
D
I
E
E
V
Q
V
L
E
V
I
D
H
H
R
I
A
N
F
E
T
A
E
P
L
Y
Y
R
A
E
P
V
G
C
T
A
T
I
L
N
K
M
Y
K
E
N
N
V
K
I
E
K
E
I
A
G
L
M
-
L
S
A
I
I
S
D
S
L
L
F
K
S
P
T
C
T
D
Q
D
V
A
A
A
K
E
L
A
E
I
A
G
V
D
A
E
-
E
Y
G
L
N
M
L
K
A
G
A
D
L
S
K
K
T
V
E
E
L
I
S
L
D
A
K
E
F
T
L
G
S
K
K
V
E
I
A
Q
V
N
T
V
D
I
E
D
V
K
K
R
Q
A
E
L
E
A
V
I
S
K
V
V
A
E
K
N
L
D
L
F
L
L
V
I
T
D
I
L
E
--
N
D
S
L
A
L
A
I
G
N
E
A
-
A
K
V
E
K
A
F
N
V
T
L
--
E
N
N
T
A
L
L
K
G
V
V
S
R
K
K
Q
V
V
P
V
L
T
D
A
M
A
-
3
PsiBlast_PDB
89.00
99%
-98
- C1 -
2IW4
8
PPAC_BACSU
A:
[2-309]
-
E
K
I
L
I
F
G
H
Q
N
P
D
T
D
T
I
C
S
A
I
A
Y
A
D
L
-
K
N
K
-
L
G
F
N
A
E
P
V
R
L
G
Q
V
N
G
E
T
Q
Y
A
L
D
Y
F
K
Q
E
S
P
R
L
V
E
T
-
A
A
N
E
-
V
N
G
V
I
L
V
D
H
N
E
R
Q
Q
S
I
K
D
I
E
E
V
Q
V
L
E
V
I
D
H
Q
R
I
A
N
F
E
T
A
E
P
L
Y
Y
R
A
E
P
V
G
C
T
A
T
I
L
N
K
M
Y
K
E
N
N
V
K
I
E
K
E
I
A
G
L
M
-
L
S
A
I
I
S
D
S
L
L
F
K
S
P
T
C
T
D
Q
D
V
A
A
A
K
E
L
A
E
I
A
G
V
D
A
E
-
E
Y
G
L
N
M
L
K
A
G
A
D
L
S
K
K
T
V
E
E
L
I
S
L
D
A
K
E
F
T
L
G
S
K
K
V
E
I
A
Q
V
N
T
V
D
I
E
D
V
K
K
R
Q
A
E
L
E
A
V
I
S
K
V
V
A
E
K
N
L
D
L
F
L
L
V
I
T
D
I
L
E
--
N
D
S
L
A
L
A
I
G
N
E
A
-
A
K
V
E
K
A
F
N
V
T
L
--
E
N
N
T
A
L
L
K
G
V
V
S
R
K
K
Q
V
V
P
V
L
T
D
A
M
A
E
11
PsiBlast_CBE
88.55
100%
-97
- C1 -
2HAW
12
PPAC_BACSU
B:
[1-308]
M
E
K
I
L
I
F
G
H
Q
N
P
D
T
D
T
I
C
S
A
I
A
Y
A
D
L
-
K
N
K
-
L
G
F
N
A
E
P
V
R
L
G
Q
V
N
G
E
T
Q
Y
A
L
D
Y
F
K
Q
E
S
P
R
L
V
E
T
-
A
A
N
E
-
V
N
G
V
I
L
V
D
H
N
E
R
Q
Q
S
I
K
D
I
E
E
V
Q
V
L
E
V
I
D
H
H
R
I
A
N
F
E
T
A
E
P
L
Y
Y
R
A
E
P
V
G
C
T
A
T
I
L
N
K
M
Y
K
E
N
N
V
K
I
E
K
E
I
A
G
L
M
-
L
S
A
I
I
S
D
S
L
L
F
K
S
P
T
C
T
D
Q
D
V
A
A
A
K
E
L
A
E
I
A
G
V
D
A
E
-
E
Y
G
L
N
M
L
K
A
G
A
D
L
S
K
K
T
V
E
E
L
I
S
L
D
A
K
E
F
T
L
G
S
K
K
V
E
I
A
Q
V
N
T
V
D
I
E
D
V
K
K
R
Q
A
E
L
E
A
V
I
S
K
V
V
A
E
K
N
L
D
L
F
L
L
V
I
T
D
I
L
E
--
N
D
S
L
A
L
A
I
G
N
E
A
-
A
K
V
E
K
A
F
N
V
T
L
--
E
N
N
T
A
L
L
K
G
V
V
S
R
K
K
Q
V
V
P
V
L
T
D
A
M
A
-
12
PsiBlast_CBE
88.51
100%
-96
- C1 -
1WPM
4
PPAC_BACSU
B:
[1-308]
M
E
K
I
L
I
F
G
H
Q
N
P
D
T
D
T
I
C
S
A
I
A
Y
A
D
L
-
K
N
K
-
L
G
F
N
A
E
P
V
R
L
G
Q
V
N
G
E
T
Q
Y
A
L
D
Y
F
K
Q
E
S
P
R
L
V
E
T
-
A
A
N
E
-
V
N
G
V
I
L
V
D
H
N
E
R
Q
Q
S
I
K
D
I
E
E
V
Q
V
L
E
V
I
D
H
H
R
I
A
N
F
E
T
A
E
P
L
Y
Y
R
A
E
P
V
G
C
T
A
T
I
L
N
K
M
Y
K
E
N
N
V
K
I
E
K
E
I
A
G
L
M
-
L
S
A
I
I
S
D
S
L
L
F
K
S
P
T
C
T
D
Q
D
V
A
A
A
K
E
L
A
E
I
A
G
V
D
A
E
-
E
Y
G
L
N
M
L
K
A
G
A
D
L
S
K
K
T
V
E
E
L
I
S
L
D
A
K
E
F
T
L
G
S
K
K
V
E
I
A
Q
V
N
T
V
D
I
E
D
V
K
K
R
Q
A
E
L
E
A
V
I
S
K
V
V
A
E
K
N
L
D
L
F
L
L
V
I
T
D
I
L
E
--
N
D
S
L
A
L
A
I
G
N
E
A
-
A
K
V
E
K
A
F
N
V
T
L
--
E
N
N
T
A
L
L
K
G
V
V
S
R
K
K
Q
V
V
P
V
L
T
D
A
M
A
-
1
PsiBlast_PDB
88.22
100%
-97
- C1 -
1WPM
3
PPAC_BACSU
A:
[2-308]
-
E
K
I
L
I
F
G
H
Q
N
P
D
T
D
T
I
C
S
A
I
A
Y
A
D
L
-
K
N
K
-
L
G
F
N
A
E
P
V
R
L
G
Q
V
N
G
E
T
Q
Y
A
L
D
Y
F
K
Q
E
S
P
R
L
V
E
T
-
A
A
N
E
-
V
N
G
V
I
L
V
D
H
N
E
R
Q
Q
S
I
K
D
I
E
E
V
Q
V
L
E
V
I
D
H
H
R
I
A
N
F
E
T
A
E
P
L
Y
Y
R
A
E
P
V
G
C
T
A
T
I
L
N
K
M
Y
K
E
N
N
V
K
I
E
K
E
I
A
G
L
M
-
L
S
A
I
I
S
D
S
L
L
F
K
S
P
T
C
T
D
Q
D
V
A
A
A
K
E
L
A
E
I
A
G
V
D
A
E
-
E
Y
G
L
N
M
L
K
A
G
A
D
L
S
K
K
T
V
E
E
L
I
S
L
D
A
K
E
F
T
L
G
S
K
K
V
E
I
A
Q
V
N
T
V
D
I
E
D
V
K
K
R
Q
A
E
L
E
A
V
I
S
K
V
V
A
E
K
N
L
D
L
F
L
L
V
I
T
D
I
L
E
--
N
D
S
L
A
L
A
I
G
N
E
A
-
A
K
V
E
K
A
F
N
V
T
L
--
E
N
N
T
A
L
L
K
G
V
V
S
R
K
K
Q
V
V
P
V
L
T
D
A
M
A
-
13
PsiBlast_CBE
87.24
99%
-94
- C1 -
2IW4
11
PPAC_BACSU
B:
[1-309]
M
E
K
I
L
I
F
G
H
Q
N
P
D
T
D
T
I
C
S
A
I
A
Y
A
D
L
-
K
N
K
-
L
G
F
N
A
E
P
V
R
L
G
Q
V
N
G
E
T
Q
Y
A
L
D
Y
F
K
Q
E
S
P
R
L
V
E
T
-
A
A
N
E
-
V
N
G
V
I
L
V
D
H
N
E
R
Q
Q
S
I
K
D
I
E
E
V
Q
V
L
E
V
I
D
H
Q
R
I
A
N
F
E
T
A
E
P
L
Y
Y
R
A
E
P
V
G
C
T
A
T
I
L
N
K
M
Y
K
E
N
N
V
K
I
E
K
E
I
A
G
L
M
-
L
S
A
I
I
S
D
S
L
L
F
K
S
P
T
C
T
D
Q
D
V
A
A
A
K
E
L
A
E
I
A
G
V
D
A
E
-
E
Y
G
L
N
M
L
K
A
G
A
D
L
S
K
K
T
V
E
E
L
I
S
L
D
A
K
E
F
T
L
G
S
K
K
V
E
I
A
Q
V
N
T
V
D
I
E
D
V
K
K
R
Q
A
E
L
E
A
V
I
S
K
V
V
A
E
K
N
L
D
L
F
L
L
V
I
T
D
I
L
E
--
N
D
S
L
A
L
A
I
G
N
E
A
-
A
K
V
E
K
A
F
N
V
T
L
--
E
N
N
T
A
L
L
K
G
V
V
S
R
K
K
Q
V
V
P
V
L
T
D
A
M
A
E
19
HHSearch
82.95
100%
-47
- C1 -
2HAW
9
PPAC_BACSU
A:
[2-308]
-
E
K
I
L
I
F
G
H
Q
N
P
D
T
D
T
I
C
S
A
I
A
Y
A
D
L
-
K
N
K
-
L
G
F
N
A
E
P
V
R
L
G
Q
V
N
G
E
T
Q
Y
A
L
D
Y
F
K
Q
E
S
P
R
L
V
E
T
-
A
A
N
E
-
V
N
G
V
I
L
V
D
H
N
E
R
Q
Q
S
I
K
D
I
E
E
V
Q
V
L
E
V
I
D
H
H
R
I
A
N
F
E
T
A
E
P
L
Y
Y
R
A
E
P
V
G
C
T
A
T
I
L
N
K
M
Y
K
E
N
N
V
K
I
E
K
E
I
A
G
L
M
-
L
S
A
I
I
S
D
S
L
L
F
K
S
P
T
C
T
D
Q
D
V
A
A
A
K
E
L
A
E
I
A
G
V
D
-
A
E
E
Y
G
L
N
M
L
K
A
G
A
D
L
S
K
K
T
V
E
E
L
I
S
L
D
A
K
E
F
T
L
G
S
K
K
V
E
I
A
Q
V
N
T
V
D
I
E
D
V
K
K
R
Q
A
E
L
E
A
V
I
S
K
V
V
A
E
K
N
L
D
L
F
L
L
V
I
T
D
I
L
E
--
N
D
S
L
A
L
A
I
G
N
E
A
-
A
K
V
E
K
A
F
N
V
T
L
--
E
N
N
T
A
L
L
K
G
V
V
S
R
K
K
Q
V
V
P
V
L
T
D
A
M
A
-
5
PsiBlast_PDB
73.65
100%
-114
- C1 -
1WPN
5
PPAC_BACSU
A:
[2-188]
-
E
K
I
L
I
F
G
H
Q
N
P
D
T
D
T
I
C
S
A
I
A
Y
A
D
L
-
K
N
K
-
L
G
F
N
A
E
P
V
R
L
G
Q
V
N
G
E
T
Q
Y
A
L
D
Y
F
K
Q
E
S
P
R
L
V
E
T
-
A
A
N
E
-
V
N
G
V
I
L
V
D
H
N
E
R
Q
Q
S
I
K
D
I
E
E
V
Q
V
L
E
V
I
D
H
H
R
I
A
N
F
E
T
A
E
P
L
Y
Y
R
A
E
P
V
G
C
T
A
T
I
L
N
K
M
Y
K
E
N
N
V
K
I
E
K
E
I
A
G
L
M
-
L
S
A
I
I
S
D
S
L
L
F
K
S
P
T
C
T
D
Q
D
V
A
A
A
K
E
L
A
E
I
A
G
V
D
A
E
-
E
Y
G
L
N
M
L
K
A
G
------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_CBE
73.44
100%
-120
- C1 -
1WPN
2
PPAC_BACSU
B:
[2-188]
-
E
K
I
L
I
F
G
H
Q
N
P
D
T
D
T
I
C
S
A
I
A
Y
A
D
L
-
K
N
K
-
L
G
F
N
A
E
P
V
R
L
G
Q
V
N
G
E
T
Q
Y
A
L
D
Y
F
K
Q
E
S
P
R
L
V
E
T
-
A
A
N
E
-
V
N
G
V
I
L
V
D
H
N
E
R
Q
Q
S
I
K
D
I
E
E
V
Q
V
L
E
V
I
D
H
H
R
I
A
N
F
E
T
A
E
P
L
Y
Y
R
A
E
P
V
G
C
T
A
T
I
L
N
K
M
Y
K
E
N
N
V
K
I
E
K
E
I
A
G
L
M
-
L
S
A
I
I
S
D
S
L
L
F
K
S
P
T
C
T
D
Q
D
V
A
A
A
K
E
L
A
E
I
A
G
V
D
A
E
-
E
Y
G
L
N
M
L
K
A
G
------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
72.04
99%
-113
- C1 -
1WPN
5
PPAC_BACSU
A:
[2-187]
-
E
K
I
L
I
F
G
H
Q
N
P
D
T
D
T
I
C
S
A
I
A
Y
A
D
L
-
K
N
K
-
L
G
F
N
A
E
P
V
R
L
G
Q
V
N
G
E
T
Q
Y
A
L
D
Y
F
K
Q
E
S
P
R
L
V
E
T
-
A
A
N
E
-
V
N
G
V
I
L
V
D
H
N
E
R
Q
Q
S
I
K
D
I
E
E
V
Q
V
L
E
V
I
D
H
H
R
I
A
N
F
E
T
A
E
P
L
Y
Y
R
A
E
P
V
G
C
T
A
T
I
L
N
K
M
Y
K
E
N
N
V
K
I
E
K
E
I
A
G
L
M
-
L
S
A
I
I
S
D
S
L
L
F
K
S
P
T
C
T
D
Q
D
V
A
A
A
K
E
L
A
E
I
A
G
V
D
-
A
E
E
Y
G
L
N
M
L
K
A
-------------------------------------------------------------------------------------------------------------------------------
35
Fugue
67.70
100%
-81
- C1 -
1K23
2
PPAC_BACSU
A:
[2-188]
-
E
K
I
L
I
F
G
H
Q
N
P
D
T
D
T
I
C
S
A
I
A
Y
A
D
L
-
K
N
K
-
L
G
F
N
A
E
P
V
R
L
G
Q
V
N
G
E
T
Q
Y
A
L
D
Y
F
K
Q
E
S
P
R
L
V
E
T
-
A
A
N
E
-
V
N
G
V
I
L
V
D
H
N
E
R
Q
Q
S
I
K
D
I
E
E
V
Q
V
L
E
V
I
D
H
H
R
I
A
N
F
E
T
A
E
P
L
Y
Y
R
A
E
P
V
G
C
T
A
T
I
L
N
K
M
Y
K
E
N
N
V
K
I
E
K
E
I
A
G
L
-
M
L
S
A
I
I
S
D
S
L
L
F
K
S
P
T
C
T
D
Q
D
V
A
A
A
K
E
L
A
E
I
A
G
V
D
A
E
-
E
Y
G
L
N
M
L
K
A
G
------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
66.66
56%
19
- C1 -
1WPP
6
PPAC_STRGC
A:
[2-309]
-
S
K
I
L
V
F
G
H
Q
N
P
D
S
D
A
I
G
S
S
Y
A
F
A
Y
L
A
R
E
A
-
Y
G
L
D
T
E
A
V
A
L
G
E
P
N
E
E
T
A
F
V
L
D
Y
F
G
V
A
A
P
R
V
I
T
S
-
A
K
A
E
G
A
E
Q
V
I
L
T
D
H
N
E
F
Q
Q
S
V
A
D
I
A
E
V
E
V
Y
G
V
V
D
H
H
R
V
A
N
F
E
T
A
S
P
L
Y
M
R
L
E
P
V
G
S
A
S
S
I
V
Y
R
M
F
K
E
H
G
V
A
V
P
K
E
I
A
G
L
M
-
L
S
G
L
I
S
D
T
L
L
L
K
S
P
T
T
H
P
T
D
K
V
I
A
P
E
L
A
E
L
A
G
V
N
L
E
-
E
Y
G
L
A
M
L
K
A
G
T
N
L
A
S
K
S
A
E
E
L
I
D
I
D
A
K
T
F
E
L
N
G
N
N
V
R
V
A
Q
V
N
T
V
D
I
A
E
V
L
E
R
Q
A
E
I
E
A
A
I
E
K
A
I
A
D
N
G
Y
S
D
F
V
L
M
I
T
D
I
I
N
--
S
N
S
E
I
L
A
I
G
S
N
M
-
D
K
V
E
A
A
F
N
F
V
L
--
E
N
N
H
A
F
L
A
G
A
V
S
R
K
K
Q
V
V
P
Q
L
T
E
S
F
--
16
PsiBlast_CBE
66.44
56%
23
- C1 -
1WPP
6
PPAC_STRGC
B:
[2-309]
-
S
K
I
L
V
F
G
H
Q
N
P
D
S
D
A
I
G
S
S
Y
A
F
A
Y
L
A
R
E
A
-
Y
G
L
D
T
E
A
V
A
L
G
E
P
N
E
E
T
A
F
V
L
D
Y
F
G
V
A
A
P
R
V
I
T
S
-
A
K
A
E
G
A
E
Q
V
I
L
T
D
H
N
E
F
Q
Q
S
V
A
D
I
A
E
V
E
V
Y
G
V
V
D
H
H
R
V
A
N
F
E
T
A
S
P
L
Y
M
R
L
E
P
V
G
S
A
S
S
I
V
Y
R
M
F
K
E
H
G
V
A
V
P
K
E
I
A
G
L
M
-
L
S
G
L
I
S
D
T
L
L
L
K
S
P
T
T
H
P
T
D
K
V
I
A
P
E
L
A
E
L
A
G
V
N
L
E
-
E
Y
G
L
A
M
L
K
A
G
T
N
L
A
S
K
S
A
E
E
L
I
D
I
D
A
K
T
F
E
L
N
G
N
N
V
R
V
A
Q
V
N
T
V
D
I
A
E
V
L
E
R
Q
A
E
I
E
A
A
I
E
K
A
I
A
D
N
G
Y
S
D
F
V
L
M
I
T
D
I
I
N
--
S
N
S
E
I
L
A
I
G
S
N
M
-
D
K
V
E
A
A
F
N
F
V
L
--
E
N
N
H
A
F
L
A
G
A
V
S
R
K
K
Q
V
V
P
Q
L
T
E
S
F
--
9
PsiBlast_PDB
65.74
56%
-0
- C1 -
1I74
5
PPAC_STRMU
A:
[2-307]
--
K
I
L
V
F
G
H
Q
N
P
D
S
D
A
I
G
S
S
M
A
Y
A
Y
L
-
K
R
Q
-
L
G
V
D
A
Q
A
V
A
L
G
N
P
N
E
E
T
A
F
V
L
D
Y
F
G
I
Q
A
P
P
V
V
K
S
-
A
Q
A
E
G
A
K
Q
V
I
L
T
D
H
N
E
F
Q
Q
S
I
A
D
I
R
E
V
E
V
V
E
V
V
D
H
H
R
V
A
N
F
E
T
A
N
P
L
Y
M
R
L
E
P
V
G
S
A
S
S
I
V
Y
R
L
Y
K
E
N
G
V
A
I
P
K
E
I
A
G
V
M
-
L
S
G
L
I
S
D
T
L
L
L
K
S
P
T
T
H
A
S
D
P
A
V
A
E
D
L
A
K
I
A
G
V
D
L
Q
-
E
Y
G
L
A
M
L
K
A
G
T
N
L
A
S
K
T
A
A
Q
L
V
D
I
D
A
K
T
F
E
L
N
G
S
Q
V
R
V
A
Q
V
N
T
V
D
I
N
E
V
L
E
R
Q
N
E
I
E
E
A
I
K
A
S
Q
A
A
N
G
Y
S
D
F
V
L
M
I
T
D
I
L
N
--
S
N
S
E
I
L
A
L
G
N
N
T
-
D
K
V
E
A
A
F
N
F
T
L
--
K
N
N
H
A
F
L
A
G
A
V
S
R
K
K
Q
V
V
P
Q
L
T
E
S
F
--
33
Fugue
64.16
56%
25
* C1 *
1K20
5
PPAC_STRGC
A:
[1-310]
-
S
K
I
L
V
F
G
H
Q
N
P
D
S
D
A
I
G
S
S
Y
A
F
A
Y
L
A
R
E
A
-
Y
G
L
D
T
E
A
V
A
L
G
E
P
N
E
E
T
A
F
V
L
D
Y
F
G
V
A
A
P
R
V
I
T
S
-
A
K
A
E
G
A
E
Q
V
I
L
T
D
H
N
E
F
Q
Q
S
V
A
D
I
A
E
V
E
V
Y
G
V
V
D
H
H
R
V
A
N
F
E
T
A
N
P
L
Y
M
R
L
E
P
V
G
S
A
S
S
I
V
Y
R
M
F
K
E
H
S
V
A
V
S
K
E
I
A
G
L
M
-
L
S
G
L
I
S
D
T
L
L
L
K
S
P
T
T
H
P
T
D
K
A
I
A
P
E
L
A
E
L
A
G
V
N
L
E
-
E
Y
G
L
A
M
L
K
A
G
T
N
L
A
S
K
S
A
E
E
L
I
D
I
D
A
K
T
F
E
L
N
G
N
N
V
R
V
A
Q
V
N
T
V
D
I
A
E
V
L
E
R
Q
A
E
I
E
A
A
I
E
K
A
I
A
D
N
G
Y
S
D
F
V
L
M
I
T
D
I
I
N
--
S
N
S
E
I
L
A
I
G
S
N
M
-
D
K
V
E
A
A
F
N
F
V
L
--
E
N
N
H
A
F
L
A
G
A
V
S
R
K
K
Q
V
V
P
Q
L
T
E
S
F
N
A
17
PsiBlast_CBE
64.15
56%
21
- C1 -
1K20
6
PPAC_STRGC
B:
[2-308]
--
K
I
L
V
F
G
H
Q
N
P
D
S
D
A
I
G
S
S
Y
A
F
A
Y
L
A
R
E
A
-
Y
G
L
D
T
E
A
V
A
L
G
E
P
N
E
E
T
A
F
V
L
D
Y
F
G
V
A
A
P
R
V
I
T
S
-
A
K
A
E
G
A
E
Q
V
I
L
T
D
H
N
E
F
Q
Q
S
V
A
D
I
A
E
V
E
V
Y
G
V
V
D
H
H
R
V
A
N
F
E
T
A
N
P
L
Y
M
R
L
E
P
V
G
S
A
S
S
I
V
Y
R
M
F
K
E
H
S
V
A
V
S
K
E
I
A
G
L
M
-
L
S
G
L
I
S
D
T
L
L
L
K
S
P
T
T
H
P
T
D
K
A
I
A
P
E
L
A
E
L
A
G
V
N
L
E
-
E
Y
G
L
A
M
L
K
A
G
T
N
L
A
S
K
S
A
E
E
L
I
D
I
D
A
K
T
F
E
L
N
G
N
N
V
R
V
A
Q
V
N
T
V
D
I
A
E
V
L
E
R
Q
A
E
I
E
A
A
I
E
K
A
I
A
D
N
G
Y
S
D
F
V
L
M
I
T
D
I
I
N
--
S
N
S
E
I
L
A
I
G
S
N
M
-
D
K
V
E
A
A
F
N
F
V
L
--
E
N
N
H
A
F
L
A
G
A
V
S
R
K
K
Q
V
V
P
Q
L
T
E
S
F
--
8
PsiBlast_PDB
63.53
56%
23
- C1 -
1K20
5
PPAC_STRGC
A:
[2-308]
--
K
I
L
V
F
G
H
Q
N
P
D
S
D
A
I
G
S
S
Y
A
F
A
Y
L
A
R
E
A
-
Y
G
L
D
T
E
A
V
A
L
G
E
P
N
E
E
T
A
F
V
L
D
Y
F
G
V
A
A
P
R
V
I
T
S
-
A
K
A
E
G
A
E
Q
V
I
L
T
D
H
N
E
F
Q
Q
S
V
A
D
I
A
E
V
E
V
Y
G
V
V
D
H
H
R
V
A
N
F
E
T
A
N
P
L
Y
M
R
L
E
P
V
G
S
A
S
S
I
V
Y
R
M
F
K
E
H
S
V
A
V
S
K
E
I
A
G
L
M
-
L
S
G
L
I
S
D
T
L
L
L
K
S
P
T
T
H
P
T
D
K
A
I
A
P
E
L
A
E
L
A
G
V
N
L
E
-
E
Y
G
L
A
M
L
K
A
G
T
N
L
A
S
K
S
A
E
E
L
I
D
I
D
A
K
T
F
E
L
N
G
N
N
V
R
V
A
Q
V
N
T
V
D
I
A
E
V
L
E
R
Q
A
E
I
E
A
A
I
E
K
A
I
A
D
N
G
Y
S
D
F
V
L
M
I
T
D
I
I
N
--
S
N
S
E
I
L
A
I
G
S
N
M
-
D
K
V
E
A
A
F
N
F
V
L
--
E
N
N
H
A
F
L
A
G
A
V
S
R
K
K
Q
V
V
P
Q
L
T
E
S
F
--
15
PsiBlast_CBE
63.05
57%
25
- C1 -
2ENX
5
PPAC_STRA5
B:
[2-307]
--
K
I
L
V
F
G
H
Q
N
P
D
S
D
A
I
G
S
S
V
A
F
A
Y
L
A
K
E
A
-
W
G
L
D
T
E
A
V
A
L
G
T
P
N
E
E
T
A
Y
V
L
D
Y
F
G
V
Q
A
P
R
V
V
E
S
-
A
K
A
E
G
V
E
T
V
I
L
T
D
H
N
E
F
Q
Q
S
I
S
D
I
K
D
V
T
V
Y
G
V
V
D
H
H
R
V
A
N
F
E
T
A
N
P
L
Y
M
R
L
E
P
V
G
S
A
S
S
I
V
Y
R
M
F
K
E
N
G
V
S
V
P
K
E
L
A
G
L
L
-
L
S
G
L
I
S
D
T
L
L
L
K
S
P
T
T
H
A
S
D
I
P
V
A
K
E
L
A
E
L
A
G
V
N
L
E
-
E
Y
G
L
E
M
L
K
A
G
T
N
L
S
S
K
T
A
A
E
L
I
D
I
D
A
K
T
F
E
L
N
G
E
A
V
R
V
A
Q
V
N
T
V
D
I
N
D
I
L
A
R
Q
E
E
I
E
V
A
I
Q
E
A
I
V
T
E
G
Y
S
D
F
V
L
M
I
T
D
I
V
N
--
S
N
S
E
I
L
A
L
G
S
N
M
-
A
K
V
E
A
A
F
E
F
T
L
--
E
N
N
H
A
F
L
A
G
A
V
S
R
K
K
Q
V
V
P
Q
L
T
E
S
---
6
PsiBlast_PDB
63.04
57%
26
- C1 -
2ENX
5
PPAC_STRA5
A:
[2-307]
--
K
I
L
V
F
G
H
Q
N
P
D
S
D
A
I
G
S
S
V
A
F
A
Y
L
A
K
E
A
-
W
G
L
D
T
E
A
V
A
L
G
T
P
N
E
E
T
A
Y
V
L
D
Y
F
G
V
Q
A
P
R
V
V
E
S
-
A
K
A
E
G
V
E
T
V
I
L
T
D
H
N
E
F
Q
Q
S
I
S
D
I
K
D
V
T
V
Y
G
V
V
D
H
H
R
V
A
N
F
E
T
A
N
P
L
Y
M
R
L
E
P
V
G
S
A
S
S
I
V
Y
R
M
F
K
E
N
G
V
S
V
P
K
E
L
A
G
L
L
-
L
S
G
L
I
S
D
T
L
L
L
K
S
P
T
T
H
A
S
D
I
P
V
A
K
E
L
A
E
L
A
G
V
N
L
E
-
E
Y
G
L
E
M
L
K
A
G
T
N
L
S
S
K
T
A
A
E
L
I
D
I
D
A
K
T
F
E
L
N
G
E
A
V
R
V
A
Q
V
N
T
V
D
I
N
D
I
L
A
R
Q
E
E
I
E
V
A
I
Q
E
A
I
V
T
E
G
Y
S
D
F
V
L
M
I
T
D
I
V
N
--
S
N
S
E
I
L
A
L
G
S
N
M
-
A
K
V
E
A
A
F
E
F
T
L
--
E
N
N
H
A
F
L
A
G
A
V
S
R
K
K
Q
V
V
P
Q
L
T
E
S
---
22
HHSearch
58.95
52%
21
- C1 -
1K20
5
PPAC_STRGC
A:
[1-309]
-
S
K
I
L
V
F
G
H
Q
N
P
D
S
D
A
I
G
S
S
Y
A
F
A
Y
L
-
A
R
E
A
Y
G
L
D
T
E
A
V
A
L
G
E
P
N
E
E
T
A
F
V
L
D
Y
F
G
V
A
A
P
R
V
I
T
S
A
K
A
E
G
-
A
E
Q
V
I
L
T
D
H
N
E
F
Q
Q
S
V
A
D
I
A
E
V
E
V
Y
G
V
V
D
H
H
R
V
A
N
F
E
T
A
N
P
L
Y
M
R
L
E
P
V
G
S
A
S
S
I
V
Y
R
M
F
K
E
H
S
V
A
V
S
K
E
I
A
G
L
M
-
L
S
G
L
I
S
D
T
L
L
L
K
S
P
T
T
H
P
T
D
K
A
I
A
P
E
L
A
E
L
A
G
V
N
-
L
E
E
Y
G
L
A
M
L
K
A
G
T
N
L
A
S
K
S
A
E
E
L
I
D
I
D
A
K
T
F
E
L
N
G
N
N
V
R
V
A
Q
V
N
T
V
D
I
A
E
V
L
E
R
Q
A
E
I
E
A
A
I
E
K
A
I
A
D
N
G
Y
S
D
F
V
L
M
I
T
D
I
I
N
S
N
S
E
I
L
A
I
G
S
N
M
D
K
V
E
A
A
F
N
F
V
L
E
N
N
H
A
F
L
A
G
A
V
-----
S
R
K
K
Q
V
V
P
Q
L
T
E
S
F
N
-