@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv0007: (2016-04-18 )
MTAPNEPGALSKGDGPNADGLVDRGGAHRAATGPGRIPDAGDPPPWQRAATRQSQAGHRQPPPVSHPEGRPTNPPAAADARLNRFISGASAPVTGPAAAVRTPQPDPDASLGCGDGSPAEAYASELPDLSGPTPRAPQRNPAPARPAEGGAGSRGDSAAGSSGGRSITAESRDARVQLSARRSRGPVRASMQIRRIDPWSTLKVSLLLSVALFFVWMITVAFLYLVLGGMGVWAKLNSNVGDLLNNASGSSAELVSSGTIFGGAFLIGLVNIVLMTALATIGAFVYNLITDLIGGIEVTLADRD
Atome Classification :
(20 SA)
----------------------------------------.........--10........20........30........40...------------.....50........60........70.....---....80........90........100.....-----------------...110--..------.......120.......130......-----.140.......150.......160.......170.......180.......190...------....200.....------.-------.210.......220....-...230-...---.....240.......250.......260.-------......270.--......280--........290.......300..----------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------MTAPNEPGA--LSKGDGPNADGLVDRGGAHRAATGPGRIPDAGDPP------------
P
W
Q
R
A
ATRQSQAGHRQPPPVSHPEGR-PTNPP---
A
A
A
D
A
R
L
N
R
F
ISGASAPVTGPAAAV-RTPQPD-----------------PDAS----LG------CGDG
S
P
A
E
A
Y
A
S
ELPDLSGPTPRAPQ-----RNPAPARPAEGGAGSRGDSAAGSSGG
R
S
I
TAESR
D
A
R
V
Q
L
S
ARRSRGPVRA
S
M
Q
I
R
R------IDP
W
S
T
L
K
V
S
L
L
------
L
-------
S
V
A
L
F
F
V
W
M
I
T
V
A
F
L
Y
L
V
-LGGM
G
--
V
W
A
---KLNS
N
V
G
D
L
L
NNASGSS
A
E
L
VSSG
T
I
F
G
G
-------
A
F
L
I
G
L
V
N
I
V
--
L
M
T
A
L
A
T
I
---
G
A
F
V
Y
N
L
I
T
D
L
IGG
I
E
V
T
LADRD----------------------------------------------------------------------------------------
31
Fugue
82.67
13%
-66
* C5 *
5GAP
-
PRP3_YEAST
G:
[150-467]
--------------------------------L
L
D
L
S
K
F
K
I
Y
Y
D
N
N
H
G
Y
EW
W
D
T
A
Y
L
D
E
K
G
E
L
M
E
K
Y
D
M
N
G
T
S
P
A
E
E
K
L
A
E
D
I
D
E
V
------------
D
D
D
D
D
D
E
H
P
S
I
R
Y
V
A
H
P
L
P
E
K
I
N
E
A
K
-
V
S
I
K
A
Y
L
T
Q
H
E
R
K
R
L
R
R
N
R
R
K
M
A
R
E
A
R
E
I
K
I
K
L
G
L
L
P
K
P
E
-----------------
P
K
V
K
----
L
S
NMMSVF
E
N
D
Q
N
I
T
D
P
T
A
W
E
K
V
V
K
D
Q
V
D
L
R
K
R
K
-----
H
L
E
E
N
E
R
R
H
E
D
A
I
K
R
R
K
E
A
V
N
M
N
------
V
E
K
P
T
V
Y
H
C
K
V
F
Q
F
K
N
L
Q
N
P
K
I
R
F
K
L
K
M
------
N
S
K
E
L
S
L
K
-
G
L
C
------
L
R
I
RDD
G
P
G
I
I
I
V
V
G
N
E
K
S
C
K
F
Y
E
N
L
-
V
M
K
R
I
--
K
W
N
E
D
F
E
L
H
T
N
T
G
D
I
K
M
D
M
H
N
N
S
I
S
K
T
W
E
G
Y
L
Q
D
C
-------
K
F
K
G
W
F
M
K
V
C
ND
Q
D
S
L
L
R
T
L
---
G
Q
F
D
S
E
H
F
Y
S
P
V
---------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
56.40
27%
23
- C6 -
5DM7
-
RL2_DEIRA
A:
[20-95]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
S
G
L
A
K
K
R
P
E
-----
K
A
L
T
E
A
L
P
K
T
G
G
R
N
N
R
G
R
I
T
S
R
F
I
G
G
----
G
H
K
R
L
Y
R
I
I
D
F
K
R
R
D
K
S
G
V
N
A
K
V
A
A
I
E
------
Y
D
P
N
R
S
A
R
I
A
L
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
56.09
15%
12
- C4 -
5GAO
-
?
E:
[5-560]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
A
A
A
A
A
A
A
A
A
--
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
------------
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
-
A
A
A
A
A
---
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
-
A
A
A
A
A
A
-----------------
A
A
A
A
----
A
A
------
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
-----
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
------
A
A
A
A
A
A
A
A
A
A
A
A
------
A
-------
A
A
A
A
------
A
A
A
A
A
A
A
A
-
A
A
A
A
A
--
A
A
A
---
A
R
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
-------
A
A
A
A
A
A
A
A
A
A
--
A
A
A
A
A
A
A
A
---
A
A
T
T
K
E
A
Y
K
K
L
S
Q
K
F
H
G
T
K
S
N
K
K
----------------------------------------------------------------------------------------
11
PsiBlast_PDB
54.97
25%
-10
- C4 -
1P91
3
RLMA_ECOLI
A:
[23-111]
----------------------------------------------------------------------------------------------------
Q
R
H
Q
F
D
M
A
K
E
G
Y
V
N
L
L
P
V
Q
H
K
R
S
R
D
P
G
D
S
A
---
E
M
M
Q
A
R
R
A
F
L
D
A
G
H
Y
Q
P
L
R
D
A
I
V
A
Q
-
L
R
E
R
L
D
-----------------
D
K
A
T
A
V
L
D
I
G
------
C
G
E
G
Y
Y
T
H
A
F
A
D
A
L
P
E
I
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
53.71
28%
40
- C6 -
3PIO
-
RL2_DEIRA
A:
[19-94]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
S
G
L
T
K
K
R
P
E
-----
K
A
L
T
E
A
L
P
K
T
G
G
R
N
N
R
G
R
I
T
S
R
F
I
G
G
----
G
H
K
R
L
Y
R
I
I
D
F
K
R
R
D
K
S
G
V
N
A
K
V
A
A
I
E
------
Y
D
P
N
R
S
A
R
I
A
L
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
53.49
12%
-7
* C3 *
1MV3
-
BIN1_HUMAN
A:
[270-482]
----------------------------------------------------------------
D
G
S
P
A
A
T
P
E
I
R
V
N
H
E
P
E
P
A
G
G
A
------------
T
P
G
A
T
L
P
K
S
P
S
Q
L
R
K
G
P
P
V
P
P
P
P
K
H
T
-
P
S
K
E
V
---
K
Q
E
Q
I
L
S
L
F
--
E
D
T
F
V
P
E
I
S
V
T
T
P
S
-
Q
P
A
E
A
S
-----------------
E
V
A
G
----
G
T
------
Q
P
A
A
G
A
Q
E
P
G
E
T
A
A
S
E
A
A
S
S
S
L
P
A
V
V
-----
V
E
T
F
P
A
T
V
N
G
T
V
E
G
G
S
G
A
G
R
L
D
L
P
P
G
F
M
F
K
V
Q
A
------
Q
H
D
Y
T
A
T
D
T
---------------------------------------------------------------------
D
---
E
L
Q
L
K
A
G
D
V
V
L
V
I
P
F
Q
N
P
E
E
Q
D
E
G
-------------
W
L
M
G
V
K
E
S
D
--
W
N
Q
H
K
K
L
E
KC
R
G
V
F
P
E
N
F
T
E
R
V
P
---------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
52.61
28%
45
* C6 *
3PIP
-
RL2_DEIRA
A:
[19-94]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
S
G
L
T
K
K
R
P
E
-----
K
A
L
T
E
A
L
P
K
T
G
G
R
N
N
R
G
R
I
T
S
R
F
I
G
G
----
G
H
K
R
L
Y
R
I
I
D
F
K
R
R
D
K
S
G
V
N
A
K
V
A
A
I
E
------
Y
D
P
N
R
S
A
R
I
A
L
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
52.25
27%
28
- C6 -
5DM6
-
RL2_DEIRA
A:
[20-95]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
S
G
L
A
K
K
R
P
E
-----
K
A
L
T
E
A
L
P
K
T
G
G
R
N
N
R
G
R
I
T
S
R
F
I
G
G
----
G
H
K
R
L
Y
R
I
I
D
F
K
R
R
D
K
S
G
V
N
A
K
V
A
A
I
E
------
Y
D
P
N
R
S
A
R
I
A
L
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
52.08
15%
-13
- C3 -
2AHJ
4
NHAB_RHOER
B:
[1-211]
----------------------------------------
M
D
G
V
H
D
L
A
----------------
G
V
Q
G
F
G
K
V
P
H
T
V
N
A
D
I
G
P
T
F
H
A
------------
E
W
E
H
L
P
Y
S
L
M
F
A
G
V
A
E
L
G
A
F
S
V
D
E
V
R
-
Y
V
V
E
R
---
M
E
P
R
H
Y
M
M
T
--
P
Y
Y
E
R
Y
V
I
G
V
A
T
L
M
-
V
E
K
G
I
L
-----------------
T
Q
D
E
----
L
E
------
S
L
A
G
------------------------------------
G
P
F
P
L
S
R
P
S
E
S
E
G
R
P
A
P
V
E
T
T
T
F
E
V
G
Q
R
V
R
V
R
D
E
Y
V
P
G
H
I
R
M
P
A
Y
C
R
G
------------
R
V
G
T
I
S
------
H
-------
R
T
T
E
K
W
P
F
P
D
A
I
G
H
------------------
G
R
N
D
A
G
E
E
P
T
Y
H
V
K
F
A
A
E
E
L
F
G
S
D
T
D
-
G
G
-------
S
V
V
V
D
L
F
E
G
Y
--
L
E
P
A
----------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
51.59
28%
47
- C6 -
4WFN
-
RL2_DEIRA
A:
[20-95]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
S
G
L
T
K
K
R
P
E
-----
K
A
L
T
E
A
L
P
K
T
G
G
R
N
N
R
G
R
I
T
S
R
F
I
G
G
----
G
H
K
R
L
Y
R
I
I
D
F
K
R
R
D
K
S
G
V
N
A
K
V
A
A
I
E
------
Y
D
P
N
R
S
A
R
I
A
L
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
50.93
28%
44
- C6 -
4U67
-
RL2_DEIRA
A:
[20-95]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
S
G
L
T
K
K
R
P
E
-----
K
A
L
T
E
A
L
P
K
T
G
G
R
N
N
R
G
R
I
T
S
R
F
I
G
G
----
G
H
K
R
L
Y
R
I
I
D
F
K
R
R
D
K
S
G
V
N
A
K
V
A
A
I
E
------
Y
D
P
N
R
S
A
R
I
A
L
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
49.70
28%
26
- C6 -
2ZJQ
-
RL2_DEIRA
A:
[33-95]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
E
A
L
P
K
T
G
G
R
N
N
R
G
R
I
T
S
R
F
I
G
G
----
G
H
K
R
L
Y
R
I
I
D
F
K
R
R
D
K
S
G
V
N
A
K
V
A
A
I
E
------
Y
D
P
N
R
S
A
R
I
A
L
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
46.13
8%
-10
- C1 -
1T8S
2
AMN_ECOLI
A:
[8-484]
----------------------------------------
L
T
P
A
Q
A
L
D
K
--
L
D
A
L
Y
E
Q
S
V
V
A
L
R
N
A
I
G
N
Y
I
T
S
G
E
L
P
D
E
N
A
R
K
Q
G
L
FV
Y
P
S
L
T
V
T
W
DG
S
T
T
N
P
P
K
T
R
A
F
G
R
F
T
H
A
G
S
Y
T
T
T
I
T
R
-
P
T
L
F
R
---
S
Y
L
N
E
Q
L
T
L
L
Y
Q
D
Y
G
A
H
I
S
V
Q
P
S
Q
H
-
E
I
P
Y
P
Y
VILD
R
S
M
S
A
G
L
T
R
YFPT
T
F
S
P
----
L
S
------
H
F
D
A
R
R
V
D
F
S
L
A
R
L
R
H
Y
T
G
T
P
V
E
H
F
Q
P
F
V
L
F
T
N
Y
T
--
R
Y
V
D
E
F
V
R
W
G
C
S
Q
I
L
D
P
D
S
P
Y
I
A
L
S
C
A
G
G
N
W
I
T
A
E
T
E
A
P
E
E
A
I
S
D
L
A
W
K
K
H
Q
M
P
A
W
H
L
I
T
A
D
G
Q
G
I
T
L
V
NIGVG
P
S
-------
N
A
K
T
I
C
D
H
L
A
V
L
R
P
D
V
W
L
M
I
G
H
C
G
--
G
L
R
---
E
-
S
Q
A
I
G
D
Y
V
L
A
H
A
Y
L
R
D
D
H
V
L
D
A
V
L
P
P
D
I
P
I
P
S
I
A
E
V
Q
R
A
L
Y
D
A
T
--
K
L
V
S
G
R
P
G
---
E
E
V
K
Q
R
L
R
T
G
T
V
V
T
T
D
D
R
N
W
E
L
R
YSAS
A
L
R
F
N
L
S
RAV
A
I
D
M
E
S
A
T
I
A
A
Q
G
Y
R
F
RV
P
Y
G
T
L
L
C
V
SDKPLHGEIKG
A
I
S
E
H
L
Q
I
G
I
R
A
I
D
L
L
R
A
EGDRLHSRKLRTFNEPPFR
12
PsiBlast_PDB
45.07
27%
47
- C4 -
4F0X
-
DCMC_HUMAN
A:
[15-90]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
T
-----------------
P
A
Y
E
----
L
R
------
E
K
T
P
A
P
A
E
G
Q
C
A
D
F
V
S
F
Y
G
G
L
A
E
T
A
Q
-----
R
A
E
L
L
G
R
L
A
R
G
F
G
V
D
H
G
Q
V
A
E
Q
S
A
G
V
L
H
L
R
Q
Q
Q
R
E
A
A
V
L
L
Q
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
43.97
14%
40
- C5 -
3IYN
-
CAP9_ADE05
Q:
[7-134]
---------------------------------------------------------------------------------
D
G
S
I
V
------------
S
S
Y
L
T
T
R
M
P
P
W
A
G
V
R
Q
N
V
M
G
S
S
I
D
G
R
-
P
V
L
P
A
---
N
S
T
T
L
T
Y
E
T
V
S
G
T
P
L
E
T
A
A
S
A
A
A
S
A
-
A
A
A
T
A
R
-----------------
G
I
V
T
----
D
F
------
A
F
L
S
P
L
A
S
S
A
A
S
R
S
S
A
R
D
D
K
L
T
A
L
L
A
-----
Q
L
D
S
L
T
R
E
L
N
V
V
S
Q
Q
L
L
D
L
R
Q
Q
V
S
A
L
K
A
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
43.22
22%
-105
- C4 -
4XTR
-
?
G:
[15-36]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
W
R
V
Y
L
L
I
V
L
------
L
-------
V
M
L
L
F
I
F
L
I
M
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
40.92
7%
-23
- C2 -
2BAF
-
A:
[1-166]
-------------------------------------------------------
M
G
T
F
R
E
E
G
S
V
S
S
G
T
K
Q
E
F
H
T
G
K
L
V
T
T
K
G
D
K
E
------------
L
L
I
D
N
E
K
V
T
S
G
H
T
T
T
T
R
R
S
C
S
K
V
I
T
K
-
T
V
T
N
A
---
D
G
R
T
E
T
T
K
E
V
V
K
S
E
D
G
S
D
C
G
D
A
D
F
D
-
W
H
H
T
F
P
-----------------
S
R
G
N
----
L
D
------
D
F
F
H
R
D
K
D
D
F
F
T
R
S
S
H
E
F
D
G
R
T
G
L
A
P
-----
E
F
A
A
L
G
E
S
G
S
S
S
S
K
T
S
T
H
S
K
Q
F
V
S
S
S
T
T
V
N
R
G
G
S
A
I
E
S
K
H
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
38.86
35%
-67
- C4 -
3DIN
-
SECG_THEMA
E:
[9-24]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
T
I
I
S
V
A
L
I
Y
M
V
-
Q
V
Q
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
35.37
18%
-77
- C4 -
4DVE
4
BIOY_LACLM
A:
[57-97]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
------
A
-------
G
G
L
L
G
P
K
Y
G
T
I
S
V
G
A
F
L
A
-
L
A
L
I
G
LP
V
L
T
---
G
G
N
G
G
A
A
S
F
L
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
32.80
21%
-100
- C4 -
3DL8
-
SECG_AQUAE
E:
[8-24]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
V
I
I
A
V
V
L
I
I
S
T
-
L
L
Q
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------