@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv0015c: (2016-04-18 )
MSPRVGVTLSGRYRLQRLIATGGMGQVWEAVDNRLGRRVAVKVLKSEFSSDPEFIERFRAEARTTAMLNHPGIASVHDYGESQMNGEGRTAYLVMELVNGEPLNSVLKRTGRLSLRHALDMLEQTGRALQIAHAAGLVHRDVKPGNILITPTGQVKITDFGIAKAVDAAPVTQTGMVMGTAQYIAPEQALGHDASPASDVYSLGVVGYEAVSGKRPFAGDGALTVAMKHIKEPPPPLPPDLPPNVRELIEITLVKNPAMRYRSGGPFADAVAAVRAGRRPPRPSQTPPPGRAAPAAIPSGTTARVAANSAGRTAASRRSRPATGGHRPPRRTFSSGQRALLWAAGVLGALAIIIAVLLVIKAPGDNSPQQAPTPTVTTTGNPPASNTGGTDASPRLNWTERGETRHSGLQSWVVPPTPHSRASLARYEIAQ
Atome Classification :
(21 SA)
.........10........20........30........40...-.....50........60........70........80........90........100.......110.......120.......130.......140.......150.......160....--...170.......---..180.....--..190--....-....200.......210.......220...--....230--..----.....----.240---.........250.......260.....-..270.--......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MSPR
V
G
V
T
LS
G
R
Y
R
L
Q
R
L
I
ATGG
M
G
Q
V
W
E
A
V
D
N
RL
G
R
R
V
A
V
K
V
L
-
K
S
E
FSS
D
P
E
F
I
E
R
F
R
A
E
AR
T
T
A
MLNHPGIA
S
V
H
DYGESQMNGEG
R
T
A
Y
L
V
M
ELVNGE
P
L
N
S
V
L
K
RTG
R
L
S
L
R
H
A
L
D
M
L
E
QTG
R
A
L
Q
I
A
H
AAGLVHRDVKPG
N
I
L
I
TPTG
Q
V
K
I
TDFGIAKAV--DAAP--VTQT
G
M
V
---
M
GTAQYIA
P
E
--
Q
ALG---HDAS-PA
S
D
V
Y
S
L
G
V
V
G
Y
EAVSGKRPFAGD
G
A
L
T
V
--
A
M
K
H
IK---EP----PPPLP----PD-----LPP
N
V
R
E
L
I
E
I
T
L
VKNP
A
M
RYRSGGP
F
-
A
D
A
V
A
A
--
V
RAGRRPPRPSQTPPPGRAAPAAIPSG
T
T
A
R
V
A
ANSAGRTAASRRSRPATGGHRPPRRTFSSGQ
R
A
L
L
W
A
A
G
V
L
G
A
L
A
I
I
I
A
V
L
L
V
I
KAPGDNSPQQAPT
P
T
V
TTTGNPPASNTGGTDASPRLNWTERG
E
T
R
H
SGLQSWVVPPTPHSRAS
L
A
R
YEIAQ
1
PsiBlast_PDB
97.79
100%
-87
- C1 -
4OW8
2
PKNA_MYCTU
A:
[3-283]
--
P
R
V
G
V
T
L
S
G
R
Y
R
L
Q
R
L
I
A
T
G
G
M
G
Q
V
W
E
A
V
D
N
R
L
G
R
R
V
A
V
K
V
L
-
K
S
E
F
S
S
D
P
E
F
I
E
R
F
R
A
E
A
R
T
T
A
M
L
N
H
P
G
I
A
S
V
H
D
Y
G
E
S
Q
-----
R
T
A
Y
L
V
M
E
L
V
N
G
E
P
L
N
S
V
L
K
R
T
G
R
L
S
L
R
H
A
L
D
M
L
E
Q
T
G
R
A
L
Q
I
A
H
A
A
G
L
V
H
R
D
V
K
P
G
N
I
L
I
T
P
T
G
Q
V
K
I
T
D
F
G
I
A
K
A
V
--
D
A
A
P
--
V
T
Q
T
G
M
V
---
M
G
T
A
Q
Y
I
A
P
E
--
Q
A
L
G
---
H
D
A
S
-
P
A
S
D
V
Y
S
L
G
V
V
G
Y
E
A
V
S
G
K
R
P
F
A
G
D
G
A
L
T
V
--
A
M
K
H
I
K
---
E
P
----
P
P
P
L
P
----
P
D
-----
L
P
P
N
V
R
E
L
I
E
I
T
L
V
K
N
P
A
M
R
Y
R
S
G
G
P
F
-
A
D
A
V
A
A
--
V
R
A
G
R
R
P
P
R
P
----------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
96.98
100%
-90
- C1 -
4OW8
2
PKNA_MYCTU
A:
[3-279]
--
P
R
V
G
V
T
L
S
G
R
Y
R
L
Q
R
L
I
A
T
G
G
M
G
Q
V
W
E
A
V
D
N
R
L
G
R
R
V
A
V
K
V
L
-
K
S
E
F
S
S
D
P
E
F
I
E
R
F
R
A
E
A
R
T
T
A
M
L
N
H
P
G
I
A
S
V
H
D
Y
G
E
S
Q
-----
R
T
A
Y
L
V
M
E
L
V
N
G
E
P
L
N
S
V
L
K
R
T
G
R
L
S
L
R
H
A
L
D
M
L
E
Q
T
G
R
A
L
Q
I
A
H
A
A
G
L
V
H
R
D
V
K
P
G
N
I
L
I
T
P
T
G
Q
V
K
I
T
D
F
G
I
A
K
A
V
--
D
A
A
P
--
V
T
Q
T
G
M
V
---
M
G
T
A
Q
Y
I
A
P
E
--
Q
A
L
G
---
H
D
A
S
-
P
A
S
D
V
Y
S
L
G
V
V
G
Y
E
A
V
S
G
K
R
P
F
A
G
D
G
A
L
T
V
--
A
M
K
H
I
K
---
E
P
----
P
P
P
L
P
----
P
D
-----
L
P
P
N
V
R
E
L
I
E
I
T
L
V
K
N
P
A
M
R
Y
R
S
G
G
P
F
-
A
D
A
V
A
A
--
V
R
A
G
R
R
--------------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
69.55
34%
-79
- C1 -
4EQM
2
?
C:
[4-278]
---
M
I
G
K
I
I
N
E
R
Y
K
I
V
D
K
L
G
G
G
G
M
S
T
V
Y
L
A
E
D
T
I
L
N
I
K
V
A
I
K
A
I
-
F
I
P
P
R
E
K
E
E
T
L
K
R
F
E
R
E
V
H
N
S
S
Q
L
S
H
Q
N
I
V
S
M
I
D
V
D
E
-----
E
D
D
C
Y
Y
L
V
M
E
Y
I
E
G
P
T
L
S
E
Y
I
E
S
H
G
P
L
S
V
D
T
A
I
N
F
T
N
Q
I
L
D
G
I
K
H
A
H
D
M
R
I
V
H
R
D
I
K
P
Q
N
I
L
I
D
S
N
K
T
L
K
I
F
D
F
G
I
A
K
A
L
--------------------
T
V
Q
Y
F
S
P
E
--
Q
A
K
G
---
E
A
T
D
-
E
C
T
D
I
Y
S
I
G
I
V
L
Y
E
M
L
V
G
E
P
P
F
N
G
E
T
A
V
S
I
--
A
I
K
H
I
Q
---
D
S
----
V
P
N
V
T
TDVR
K
D
-----
I
P
Q
S
L
S
N
V
I
L
R
A
T
E
K
D
K
A
N
R
Y
K
T
I
Q
E
M
-
K
D
D
L
S
S
--
V
L
H
E
N
R
--------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
69.26
34%
-81
- C1 -
4EQM
2
?
B:
[4-278]
---
M
I
G
K
I
I
N
E
R
Y
K
I
V
D
K
L
G
G
G
G
M
S
T
V
Y
L
A
E
D
T
I
L
N
I
K
V
A
I
K
A
I
-
F
I
P
P
R
E
K
E
E
T
L
K
R
F
E
R
E
V
H
N
S
S
Q
L
S
H
Q
N
I
V
S
M
I
D
V
D
E
-----
E
D
D
C
Y
Y
L
V
M
E
Y
I
E
G
P
T
L
S
E
Y
I
E
S
H
G
P
L
S
V
D
T
A
I
N
F
T
N
Q
I
L
D
G
I
K
H
A
H
D
M
R
I
V
H
R
D
I
K
P
Q
N
I
L
I
D
S
N
K
T
L
K
I
F
D
F
G
I
A
K
A
L
--------------------
T
V
Q
Y
F
S
P
E
--
Q
A
K
G
---
E
A
T
D
-
E
C
T
D
I
Y
S
I
G
I
V
L
Y
E
M
L
V
G
E
P
P
F
N
G
E
T
A
V
S
I
--
A
I
K
H
I
Q
---
D
S
----
V
P
N
V
T
TDVR
K
D
-----
I
P
Q
S
L
S
N
V
I
L
R
A
T
E
K
D
K
A
N
R
Y
K
T
I
Q
E
M
-
K
D
D
L
S
S
--
V
L
H
E
N
R
--------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
67.51
34%
-80
- C1 -
4EQM
2
?
A:
[4-278]
---
M
I
G
K
I
I
N
E
R
Y
K
I
V
D
K
L
G
G
G
G
M
S
T
V
Y
L
A
E
D
T
I
L
N
I
K
V
A
I
K
A
I
-
F
I
P
P
R
E
K
E
E
T
L
K
R
F
E
R
E
V
H
N
S
S
Q
L
S
H
Q
N
I
V
S
M
I
D
V
D
E
-----
E
D
D
C
Y
Y
L
V
M
E
Y
I
E
G
P
T
L
S
E
Y
I
E
S
H
G
P
L
S
V
D
T
A
I
N
F
T
N
Q
I
L
D
G
I
K
H
A
H
D
M
R
I
V
H
R
D
I
K
P
Q
N
I
L
I
D
S
N
K
T
L
K
I
F
D
F
G
I
A
K
A
L
--------------------
T
V
Q
Y
F
S
P
E
--
Q
A
K
G
---
E
A
T
D
-
E
C
T
D
I
Y
S
I
G
I
V
L
Y
E
M
L
V
G
E
P
P
F
N
G
E
T
A
V
S
I
--
A
I
K
H
I
Q
---
D
S
----
V
P
N
V
T
TDVR
K
D
-----
I
P
Q
S
L
S
N
V
I
L
R
A
T
E
K
D
K
A
N
R
Y
K
T
I
Q
E
M
-
K
D
D
L
S
S
--
V
L
H
E
N
R
--------------------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
67.45
34%
-79
- C1 -
4EQM
1
?
D:
[4-278]
---
M
I
G
K
I
I
N
E
R
Y
K
I
V
D
K
L
G
G
G
G
M
S
T
V
Y
L
A
E
D
T
I
L
N
I
K
V
A
I
K
A
I
-
F
I
P
P
R
E
K
E
E
T
L
K
R
F
E
R
E
V
H
N
S
S
Q
L
S
H
Q
N
I
V
S
M
I
D
V
D
E
-----
E
D
D
C
Y
Y
L
V
M
E
Y
I
E
G
P
T
L
S
E
Y
I
E
S
H
G
P
L
S
V
D
T
A
I
N
F
T
N
Q
I
L
D
G
I
K
H
A
H
D
M
R
I
V
H
R
D
I
K
P
Q
N
I
L
I
D
S
N
K
T
L
K
I
F
D
F
G
I
A
K
----------------------
T
V
Q
Y
F
S
P
E
--
Q
A
K
G
---
E
A
T
D
-
E
C
T
D
I
Y
S
I
G
I
V
L
Y
E
M
L
V
G
E
P
P
F
N
G
E
T
A
V
S
I
--
A
I
K
H
I
Q
---
D
S
----
V
P
N
V
T
TDVR
K
D
-----
I
P
Q
S
L
S
N
V
I
L
R
A
T
E
K
D
K
A
N
R
Y
K
T
I
Q
E
M
-
K
D
D
L
S
S
--
V
L
H
E
N
R
--------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
67.40
34%
-79
- C1 -
4EQM
1
?
F:
[4-278]
---
M
I
G
K
I
I
N
E
R
Y
K
I
V
D
K
L
G
G
G
G
M
S
T
V
Y
L
A
E
D
T
I
L
N
I
K
V
A
I
K
A
I
-
F
I
P
P
R
E
K
E
E
T
L
K
R
F
E
R
E
V
H
N
S
S
Q
L
S
H
Q
N
I
V
S
M
I
D
V
D
E
-----
E
D
D
C
Y
Y
L
V
M
E
Y
I
E
G
P
T
L
S
E
Y
I
E
S
H
G
P
L
S
V
D
T
A
I
N
F
T
N
Q
I
L
D
G
I
K
H
A
H
D
M
R
I
V
H
R
D
I
K
P
Q
N
I
L
I
D
S
N
K
T
L
K
I
F
D
F
G
I
A
K
----------------------
T
V
Q
Y
F
S
P
E
--
Q
A
K
G
---
E
A
T
D
-
E
C
T
D
I
Y
S
I
G
I
V
L
Y
E
M
L
V
G
E
P
P
F
N
G
E
T
A
V
S
I
--
A
I
K
H
I
Q
---
D
S
----
V
P
N
V
T
TDVR
K
D
-----
I
P
Q
S
L
S
N
V
I
L
R
A
T
E
K
D
K
A
N
R
Y
K
T
I
Q
E
M
-
K
D
D
L
S
S
--
V
L
H
E
N
R
--------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
66.78
34%
-77
- C1 -
4EQM
1
?
E:
[4-278]
---
M
I
G
K
I
I
N
E
R
Y
K
I
V
D
K
L
G
G
G
G
M
S
T
V
Y
L
A
E
D
T
I
L
N
I
K
V
A
I
K
A
I
-
F
I
P
P
R
E
K
E
E
T
L
K
R
F
E
R
E
V
H
N
S
S
Q
L
S
H
Q
N
I
V
S
M
I
D
V
D
E
-----
E
D
D
C
Y
Y
L
V
M
E
Y
I
E
G
P
T
L
S
E
Y
I
E
S
H
G
P
L
S
V
D
T
A
I
N
F
T
N
Q
I
L
D
G
I
K
H
A
H
D
M
R
I
V
H
R
D
I
K
P
Q
N
I
L
I
D
S
N
K
T
L
K
I
F
D
F
G
I
A
K
----------------------
T
V
Q
Y
F
S
P
E
--
Q
A
K
G
---
E
A
T
D
-
E
C
T
D
I
Y
S
I
G
I
V
L
Y
E
M
L
V
G
E
P
P
F
N
G
E
T
A
V
S
I
--
A
I
K
H
I
Q
---
D
S
----
V
P
N
V
T
TDVR
K
D
-----
I
P
Q
S
L
S
N
V
I
L
R
A
T
E
K
D
K
A
N
R
Y
K
T
I
Q
E
M
-
K
D
D
L
S
S
--
V
L
H
E
N
R
--------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
64.80
41%
-76
- C1 -
3ORK
3
?
A:
[10-288]
--------
L
S
D
R
Y
E
L
G
E
I
L
G
F
G
G
M
S
E
V
H
L
A
R
D
L
R
D
H
R
D
V
A
V
K
V
L
-
R
A
D
L
A
R
D
P
S
F
Y
L
R
F
R
R
E
A
Q
N
A
A
A
L
N
H
P
A
I
V
A
V
Y
D
T
G
E
A
E
T
P
A
-
G
P
L
P
Y
I
V
M
E
Y
V
D
G
V
T
L
R
D
I
V
H
T
E
G
P
M
T
P
K
R
A
I
E
V
I
A
D
A
C
Q
A
L
N
F
S
H
Q
N
G
I
I
H
R
D
V
K
P
A
N
I
M
I
S
A
T
N
A
V
K
V
M
D
F
G
I
A
-----------------------
T
A
Q
Y
L
S
P
E
--
Q
A
R
G
---
D
S
V
D
-
A
R
S
D
V
Y
S
L
G
C
V
L
Y
E
V
L
T
G
E
P
P
F
T
G
D
S
P
V
S
V
--
A
Y
Q
H
V
R
---
E
------
D
P
I
P
----
P
S
ARHEG
L
S
A
D
L
D
A
V
V
L
K
A
L
A
K
N
P
E
N
R
Y
Q
T
A
A
E
M
-
R
A
D
L
V
R
--
V
H
N
G
E
P
P
E
A
P
----------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
64.67
41%
-76
- C1 -
3F61
5
PKNB_MYCTU
A:
[10-288]
--------
L
S
D
R
Y
E
L
G
E
I
L
G
F
G
G
M
S
E
V
H
L
A
R
D
L
R
D
H
R
D
V
A
V
K
V
L
-
R
A
D
L
A
R
D
P
S
F
Y
L
R
F
R
R
E
A
Q
N
A
A
A
L
N
H
P
A
I
V
A
V
Y
D
T
G
E
A
E
T
P
A
-
G
P
L
P
Y
I
V
M
E
Y
V
D
G
V
T
L
R
D
I
V
H
T
E
G
P
M
T
P
K
R
A
I
E
V
I
A
D
A
C
Q
A
L
N
F
S
H
Q
N
G
I
I
H
R
D
V
K
P
A
N
I
M
I
S
A
T
N
A
V
K
V
M
D
F
G
I
A
------------------------
A
Q
Y
L
S
P
E
--
Q
A
R
G
---
D
S
V
D
-
A
R
S
D
V
Y
S
L
G
C
V
L
Y
E
V
L
T
G
E
P
P
F
T
G
D
S
P
D
S
V
--
A
Y
Q
H
V
R
---
E
------
D
P
I
P
----
P
S
ARHEG
L
S
A
D
L
D
A
V
V
L
K
A
L
A
K
N
P
E
N
R
Y
Q
T
A
A
E
M
-
R
A
D
L
V
R
--
V
H
N
G
E
P
P
E
A
P
----------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
64.41
43%
-77
- C1 -
1O6Y
3
PKNB_MYCTU
A:
[27-294]
--------
L
S
D
R
Y
E
L
G
E
I
L
G
F
G
G
M
S
E
V
H
L
A
R
D
L
R
L
H
R
D
V
A
V
K
V
L
-
R
A
D
L
A
R
D
P
S
F
Y
L
R
F
R
R
E
A
Q
N
A
A
A
L
N
H
P
A
I
V
A
V
Y
D
T
G
E
A
E
T
P
A
-
G
P
L
P
Y
I
V
M
E
Y
V
D
G
V
T
L
R
D
I
V
H
T
E
G
P
M
T
P
K
R
A
I
E
V
I
A
D
A
C
Q
A
L
N
F
S
H
Q
N
G
I
I
H
R
D
V
K
P
A
N
I
M
I
S
A
T
N
A
V
K
V
M
D
F
G
I
A
R
A
I
A---------------------
Q
Y
L
S
P
E
--
Q
A
R
G
---
D
S
V
D
-
A
R
S
D
V
Y
S
L
G
C
V
L
Y
E
V
L
T
G
E
P
P
F
T
G
D
S
P
V
S
V
--
A
Y
Q
H
V
R
---
E
------
D
P
I
P
----
P
S
ARHEG
L
S
A
D
L
D
A
V
V
L
K
A
L
A
K
N
P
E
N
R
Y
Q
T
A
A
E
M
R
A
D
L
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
63.95
41%
-70
- C1 -
3ORO
2
?
A:
[12-288]
----------
D
R
Y
E
L
G
E
I
L
G
F
G
G
M
S
E
V
H
L
A
R
D
L
R
D
H
R
D
V
A
V
K
V
L
-
R
A
D
L
A
R
D
P
S
F
Y
L
R
F
R
R
E
A
Q
N
A
A
A
L
N
H
P
A
I
V
A
V
Y
D
T
G
E
A
E
T
P
A
-
G
P
L
P
Y
I
V
M
E
Y
V
D
G
V
T
L
R
D
I
V
H
T
E
G
P
M
T
P
K
R
A
I
E
V
I
A
D
A
C
Q
A
L
N
F
S
H
Q
N
G
I
I
H
R
D
V
K
P
A
N
I
M
I
S
A
T
N
A
V
K
V
M
D
F
G
I
A
R
A
I
A----------
T
A
A
V
---
I
G
T
A
Q
Y
L
S
P
E
--
Q
A
R
G
---
D
S
V
D
-
A
R
S
D
V
Y
S
L
G
C
V
L
Y
E
V
L
T
G
E
P
P
F
T
G
D
S
P
V
S
V
--
A
Y
Q
H
V
R
---
E
------
D
P
I
P
----
P
S
ARHEG
L
S
A
D
L
D
A
V
V
L
K
A
L
A
K
N
P
E
N
R
Y
Q
T
A
A
E
M
-
R
A
D
L
V
R
--
V
H
N
G
E
P
P
E
A
P
----------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
61.82
43%
-77
- C1 -
2FUM
1
PKNB_MYCTU
C:
[27-294]
--------
L
S
D
R
Y
E
L
G
E
I
L
G
F
G
G
M
S
E
V
H
L
A
R
D
L
R
L
H
R
D
V
A
V
K
V
L
-
R
A
D
L
A
R
D
P
S
F
Y
L
R
F
R
R
E
A
Q
N
A
A
A
L
N
H
P
A
I
V
A
V
Y
D
T
G
E
A
E
T
P
A
-
G
P
L
P
Y
I
V
M
E
Y
V
D
G
V
T
L
R
D
I
V
H
T
E
G
P
M
T
P
K
R
A
I
E
V
I
A
D
A
C
Q
A
L
N
F
S
H
Q
N
G
I
I
H
R
D
V
K
P
A
N
I
M
I
S
A
T
N
A
V
K
V
M
D
F
---------------------------
A
Q
Y
L
S
P
E
--
Q
A
R
G
---
D
S
V
D
-
A
R
S
D
V
Y
S
L
G
C
V
L
Y
E
V
L
T
G
E
P
P
F
T
G
D
S
P
V
S
V
--
A
Y
Q
H
V
R
---
E
------
D
P
I
P
----
P
S
ARHEG
L
S
A
D
L
D
A
V
V
L
K
A
L
A
K
N
P
E
N
R
Y
Q
T
A
A
E
M
R
A
D
L
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
61.54
41%
-71
- C1 -
3ORT
2
?
A:
[10-288]
--------
L
S
D
R
Y
E
L
G
E
I
L
G
F
G
G
M
S
E
V
H
L
A
R
D
L
R
D
H
R
D
V
A
V
K
V
L
-
R
A
D
L
A
R
D
P
S
F
Y
L
R
F
R
R
E
A
Q
N
A
A
A
L
N
H
P
A
I
V
A
V
Y
D
T
G
E
A
E
T
P
A
-
G
P
L
P
Y
I
V
M
E
Y
V
D
G
V
T
L
R
D
I
V
H
T
E
G
P
M
T
P
K
R
A
I
E
V
I
A
D
A
C
Q
A
L
N
F
S
H
Q
N
G
I
I
H
R
D
V
K
P
A
N
I
M
I
S
A
T
N
A
V
K
V
M
D
F
G
I
A
R
-----------------------
A
Q
Y
L
S
P
E
--
Q
A
R
G
---
D
S
V
D
-
A
R
S
D
V
Y
S
L
G
C
V
L
Y
E
V
L
T
G
E
P
P
F
T
G
D
S
P
V
S
V
--
A
Y
Q
H
V
R
---
E
------
D
P
I
P
----
P
S
ARHEG
L
S
A
D
L
D
A
V
V
L
K
A
L
A
K
N
P
E
N
R
Y
Q
T
A
A
E
M
-
R
A
D
L
V
R
--
V
H
N
G
E
P
P
E
A
P
----------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
61.50
41%
-71
- C1 -
3ORP
1
?
A:
[10-288]
--------
L
S
D
R
Y
E
L
G
E
I
L
G
F
G
G
M
S
E
V
H
L
A
R
D
L
R
D
H
R
D
V
A
V
K
V
L
-
R
A
D
L
A
R
D
P
S
F
Y
L
R
F
R
R
E
A
Q
N
A
A
A
L
N
H
P
A
I
V
A
V
Y
D
T
G
E
A
E
T
P
A
-
G
P
L
P
Y
I
V
M
E
Y
V
D
G
V
T
L
R
D
I
V
H
T
E
G
P
M
T
P
K
R
A
I
E
V
I
A
D
A
C
Q
A
L
N
F
S
H
Q
N
G
I
I
H
R
D
V
K
P
A
N
I
M
I
S
A
T
N
A
V
K
V
M
D
F
G
I
A
---------------------
I
G
T
A
Q
Y
L
S
P
E
--
Q
A
R
G
---
D
S
V
D
-
A
R
S
D
V
Y
S
L
G
C
V
L
Y
E
V
L
T
G
E
P
P
F
T
G
D
S
P
V
S
V
--
A
Y
Q
H
V
R
---
E
------
D
P
I
P
----
P
S
ARHEG
L
S
A
D
L
D
A
V
V
L
K
A
L
A
K
N
P
E
N
R
Y
Q
T
A
A
E
M
-
R
A
D
L
V
R
--
V
H
N
G
E
P
P
E
A
P
----------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
61.40
41%
-72
- C1 -
3ORM
2
?
A:
[13-288]
-----------
R
Y
E
L
G
E
I
L
G
F
G
G
M
S
E
V
H
L
A
R
D
L
R
L
H
R
D
V
A
V
K
V
L
-
R
A
D
L
A
R
D
P
S
F
Y
L
R
F
R
R
E
A
Q
N
A
A
A
L
N
H
P
A
I
V
A
V
Y
A
T
G
E
A
E
T
P
A
-
G
P
L
P
Y
I
V
M
E
Y
V
D
G
V
T
L
R
D
I
V
H
T
E
G
P
M
T
P
K
R
A
I
E
V
I
A
D
A
C
Q
A
L
N
F
S
H
Q
N
G
I
I
H
R
D
V
K
P
A
N
I
M
I
S
A
T
N
A
V
K
V
M
D
F
G
I
A
R
A
I
A-------------------
T
A
Q
Y
L
S
P
E
--
Q
A
R
G
---
D
S
V
D
-
A
R
S
D
V
Y
S
L
G
C
V
L
Y
E
V
L
T
G
E
P
P
F
T
G
D
S
P
V
S
V
--
A
Y
Q
H
V
R
---
E
------
D
P
I
P
----
P
S
A
R
H
EG
L
S
A
D
L
D
A
V
V
L
K
A
L
A
K
N
P
E
N
R
Y
Q
T
A
A
E
M
-
R
A
D
L
V
R
--
V
H
N
G
E
P
P
E
A
P
----------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
59.71
24%
-73
- C1 -
4FR4
2
ST32A_HUMAN
A:
[12-279]
-------
V
N
F
D
H
F
E
I
L
R
A
I
G
K
G
S
F
G
K
V
C
I
V
Q
K
N
D
T
K
K
M
Y
A
M
K
Y
M
-
N
K
Q
K
C
V
E
R
N
E
V
R
N
V
F
K
E
L
Q
I
M
Q
G
L
E
H
P
F
L
V
N
L
W
Y
S
F
Q
D
-----
E
E
D
M
F
M
V
V
D
L
L
L
G
G
D
L
R
Y
H
L
Q
Q
N
V
H
F
K
E
E
T
V
K
L
F
I
C
E
L
V
M
A
L
D
Y
L
Q
N
Q
R
I
I
H
R
D
M
K
P
D
N
I
L
L
D
E
H
G
H
V
H
I
T
D
F
N
I
A
A
M
L
--
P
R
E
T
----
Q
I
T
T
M
---
A
G
T
K
P
Y
M
A
P
E
--
M
F
S
S
RKG
A
G
Y
S
-
F
A
V
D
W
W
S
L
G
V
T
A
Y
E
L
L
R
G
R
R
P
Y
H
I
R
S
S
T
S
S
K
E
I
V
H
T
F
E
---
T
T
----
V
V
T
Y
P
----
S
A
-----
W
S
Q
E
M
V
S
L
L
K
K
L
L
E
P
N
P
D
Q
R
F
S
Q
L
S
D
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
59.55
43%
-69
- C1 -
2FUM
1
PKNB_MYCTU
A:
[27-294]
--------
L
S
D
R
Y
E
L
G
E
I
L
G
F
G
G
M
S
E
V
H
L
A
R
D
L
R
L
H
R
D
V
A
V
K
V
L
-
R
A
D
L
A
R
D
P
S
F
Y
L
R
F
R
R
E
A
Q
N
A
A
A
L
N
H
P
A
I
V
A
V
Y
D
T
G
E
A
E
T
P
A
-
G
P
L
P
Y
I
V
M
E
Y
V
D
G
V
T
L
R
D
I
V
H
T
E
G
P
M
T
P
K
R
A
I
E
V
I
A
D
A
C
Q
A
L
N
F
S
H
Q
N
G
I
I
H
R
D
V
K
P
A
N
I
M
I
S
A
T
N
A
V
K
V
M
D
F
G
I
A
R
A
I
AD-----------------
G
T
A
Q
Y
L
S
P
E
--
Q
A
R
G
---
D
S
V
D
-
A
R
S
D
V
Y
S
L
G
C
V
L
Y
E
V
L
T
G
E
P
P
F
T
G
D
S
P
V
S
V
--
A
Y
Q
H
V
R
---
E
------
D
P
I
P
----
P
S
ARHEG
L
S
A
D
L
D
A
V
V
L
K
A
L
A
K
N
P
E
N
R
Y
Q
T
A
A
E
M
R
A
D
L
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
56.81
30%
-71
- C1 -
2R0I
-
MARK2_RAT
A:
[51-292]
----------
G
N
Y
R
L
L
K
T
I
G
K
G
N
F
A
K
V
K
L
A
R
H
I
L
T
G
K
E
V
A
V
K
I
I
D
K
T
Q
L
N
S
S
S
--
L
Q
K
L
F
R
E
V
R
I
M
K
V
L
N
H
P
N
I
V
K
L
F
E
V
I
E
T
E
-----
K
T
L
Y
L
V
M
E
Y
A
S
G
G
E
V
F
D
Y
L
V
A
H
G
R
M
K
E
K
E
A
R
A
K
F
R
Q
I
V
S
A
V
Q
Y
C
H
Q
K
F
I
V
H
R
D
L
K
A
E
N
L
L
L
D
A
D
M
N
I
K
I
A
D
F
-------------------------
G
S
P
P
Y
A
A
P
E
--
L
F
Q
G
---
K
K
Y
D
G
P
E
V
D
V
W
S
L
G
V
I
L
Y
T
L
V
S
G
S
L
P
F
D
G
Q
N
-------
L
K
E
L
R
---
E
R
V
L
R
G
K
Y
R
I
P
----
F
Y
-----
M
S
T
D
C
E
N
L
L
K
K
F
L
I
L
N
P
S
K
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
56.67
29%
-72
- C1 -
4CZU
7
CIPKN_ARATH
A:
[6-281]
-----
G
R
T
R
V
G
K
Y
E
L
G
R
T
L
G
E
G
T
F
A
K
V
K
F
A
R
N
V
E
N
G
D
N
V
A
I
K
V
I
-
D
K
E
K
V
L
K
N
K
M
I
A
Q
I
K
R
E
I
S
T
M
K
L
I
K
H
P
N
V
I
R
M
F
E
V
M
A
S
K
T
K
-----
I
Y
F
V
L
E
F
V
T
G
G
E
L
F
D
K
I
S
S
N
G
R
L
K
E
D
E
A
R
K
Y
F
Q
Q
L
I
N
A
V
D
Y
C
H
S
R
G
V
Y
H
R
D
L
K
P
E
N
L
L
L
D
A
N
G
A
L
K
V
S
D
F
G
L
S
------
A
L
P
QQ
V
R
E
D
G
L
L
HDT
C
G
T
P
N
Y
V
A
P
E
V
I
N
N
K
G
---
Y
D
G
A
-
K
A
-
D
L
W
S
C
G
V
I
L
F
V
L
M
A
G
Y
L
P
F
E
-
D
S
N
L
T
S
--
L
Y
K
K
I
F
---
K
A
----
E
F
T
C
P
----
P
W
-----
F
S
A
S
A
K
K
L
I
K
R
I
L
D
P
N
P
A
T
R
I
----
T
F
-
A
E
V
I
E
N
EW
F
K
K
G
Y
K
A
P
K
-----------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
49.52
30%
-69
- C1 -
3MVJ
4
KAPCA_HUMAN
A:
[68-300]
----------------
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
T
G
N
H
Y
A
M
K
I
L
-
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
A
V
N
F
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
-----
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
F
A
K
R
V
--
K
G
------
R
T
W
T
L
---
C
G
T
P
E
Y
L
A
P
E
--
I
I
L
S
---
K
G
Y
N
-
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
F
A
D
Q
P
I
Q
I
--
Y
E
K
I
V
S
G
K
V
R
F
----
P
S
H
F
S
----
S
D
-----
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------