@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv0048c: (2016-04-19 )
MAKWLGAPLARGVSTATRAKDSDRQDACRILDDALRDGELSMEEHRERVSAATKAVTLGDLQRLVADLQVESAPAQMPALKSRAKRTELGLLAAAFVASVLLGVGIGWGVYGNTRSPLDFTSDPGAKPDGIAPVVLTPPRQLHSLGGLTGLLEQTRKRFGDTMGYRLVIYPEYASLDRVDPADDRRVLAYTYRGGWGDATSSAKSIADVSVVDLSKFDAKTAVGIMRGAPETLGLKQSDVKSMYLIVEPVKDPTTPAALSLSLYVSSDYGGGYLVFAGDGTIKHVSYPS
Atome Classification :
(20 SA)
--.........-10........20........30----......-..40..--...-...50.----------------.......60........70.-------..----.....80...--.....90..-------......100........110........120.......130....-...140....------------.-..150....----...160.......170......-.180.......-190----.......200......------.210.......220.....--..230.......240.-------......250.......260----------------....-....270-.......280.......--------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--MAKWLG
A
P
L
-ARGV
S
T
ATRAKDS
D
R
Q
D
A
C
R
I
L
----
D
D
A
LRD-GEL
S
M
E
--
E
H
R
-
E
R
V
S
A
A
----------------TKA
V
T
L
G
D
L
Q
R
L
V
A
D
L
QVES-------AP----AQ
M
P
A
L
K
S
R
A
--
K
R
T
E
L
G
L
L
A
-------
A
A
F
V
A
S
V
L
-
L
G
VGIGWGV-YGNTRSPLDFTSDPGAKPDG
I
A
P
V
V
L-T
P
P
R
Q
L
H
S
LG------------
G
-
L
T
G
L
L
E
Q
T
R
----
K
RFGDTM
G
Y
R
L
V
I
Y
PEYASLDR-VDPADD
R
R
V
L
A
-
Y
T
Y----RGGWGDATSSAKS
I
A
D
------
V
S
V
V
D
LSKFD
A
K
T
A
V
GIMR--GAPETLGL
K
Q
SDV
K
S
M
-------
Y
L
I
V
EPVKDPTTP
A
A
L
S
L
-----------------
S
L
Y
V
-SSDYG
G
G
-
Y
L
V
F
AGDG
T
I
K
HVSYPS--------
27
Fugue
80.99
19%
-45
* C2 *
3K0B
2
?
A:
[1-384]
SS
G
R
E
N
L
Y
F
Q
G
M
K
S
F
Q
L
V
A
T
A
A
S
G
L
E
A
I
V
G
K
E
V
A
R
L
GY
D
P
K
V
E
N
-
G
K
V
Y
F
E
--
G
D
L
-
S
A
I
A
R
A
N
L
W
LRVAD
R
V
K
I
VV
G
V
F
K
A
T
T
F
D
E
L
F
E
K
T
K
A
L
P
W
E
D
YLPLD
A
Q
F
P
----
V
A
G
K
S
V
K
S
T
L
YS
V
P
D
C
Q
A
I
V
K
-------
K
A
I
V
N
R
V
S
-
E
K
Y
R
R
S
G
R
L
M
E
T
G
A
L
F
K
L
E
V
S
I
L
-----
K
D
E
V
T
L
T
I
D
T
S
G
A
G
L
H
K
R
G
YRLAQGSAPIK
E
T
M
A
A
A
L
V
L
L
T
S
WHPD
R
P
F
Y
D
P
V
C
G
S
G
T
I
P
I
E
A
A
L
I
G
Q
N
I
A
P
G
F
N
R
E
F
V
S
-
E
T
W
DWMP
K
Q
V
W
A
D
A
R
Q
E
A
E
D
L
A
N
YDQPLN
I
I
G
G
D
I
D
A
R
L
I
E
I
A
K
Q
N
A
V
E
A
G
L
G
D
L
I
T
F
R
Q
L
Q
V
A
D
F
QTEDEY
G
V
V
V
A
N
P
P
Y
G
E
R
L
E
D
E
E
A
V
R
Q
L
Y
R
E
M
G
I
V
Y
K
R
M
PT
W
S
V
Y
V
-
L
T
S
Y
E
L
F
-
E
E
V
Y
G
K
K
A
T
K
K
R
K
L
Y
R
T
D
L
Y
Q
Y
W
G
P
30
Fugue
74.45
12%
-44
- C2 -
3LLM
3
DHX9_HUMAN
A:
[1-235]
--
V
V
P
W
S
P
P
Q
S
-
N
W
N
P
W
T
S
S
N
I
D
E
G
P
L
A
F
A
------------------
T
P
E
--
Q
I
S
M
D
L
K
N
E
L
M
---------------
Y
Q
L
E
Q
D
H
D
L
Q
A
I
L
Q
E
R
E
L
L
P
-------
V
K
----
K
F
E
S
E
I
L
E
A
I
--
S
Q
N
S
V
V
I
I
R
G
A
TGCGK
T
T
Q
V
P
Q
F
I
-
L
D
D
F
I
Q
---------------
N
D
R
A
A
E
----
C
N
I
V
V
-
T
Q
P
R
R
I
S
A
V
S
------------
V
-
A
E
R
V
A
F
E
R
G
----
E
E
P
G
K
S
C
G
Y
S
V
-------
R
F
E
S
-
I
L
P
R
P
H
A
--
S
I
M
F
C
T
----
V
G
V
L
L
R
K
L
E
A
G
I
R
G
I
S
------
H
V
I
V
D
--------------------
E
I
H
E
R
D
I
N
T
D
F
L
-------
L
V
V
L
R
D
V
V
Q
A
Y
P
E
----
V
-----------------
R
I
V
L
M
S
A
T
I
D
T
S
M
F
C
E
Y
F
F
N
C
P
I
I
E
V
------------
24
Fugue
62.52
15%
-19
- C1 -
5HDA
2
ZMY11_HUMAN
A:
[3-123]
--------------------
R
M
K
S
D
H
K
R
E
T
E
R
V
V
----
R
E
A
L
E
K
-
L
R
S
E
M
E
--
E
E
K
-
R
Q
A
V
N
K
----------------
A
V
A
N
M
Q
G
E
M
D
R
K
C
K
Q
V
K
E
K
C
-------
K
E
----
E
F
V
E
E
I
K
K
L
A
--
T
Q
H
K
Q
L
I
S
Q
-------
T
K
K
K
Q
W
C
Y
N
C
E
E
E
A
M
Y
H
C
-
C
W
N
----
T
S
Y
C
S
I
K
C
Q
Q
E
H
W
H
A
E
H
K
R
-
T
C
R
R
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
56.72
30%
2
- C1 -
1ST6
-
VINC_CHICK
A:
[293-379]
-----------------------
D
A
G
E
Q
A
I
R
Q
I
L
----
D
E
A
G
K
A
-
G
E
L
C
A
G
--
K
E
R
-
R
E
I
L
G
T
----------------
C
K
--
T
L
G
Q
M
T
D
Q
L
A
D
L
R
A
R
G
-------
Q
G
----
A
-
T
P
M
A
M
Q
K
A
--
Q
Q
V
S
Q
G
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
55.58
16%
-26
* C3 *
1XKP
-
YOPN_YERPE
A:
[33-268]
----
Q
F
R
G
E
S
V
-
Q
I
V
S
G
T
L
Q
S
I
A
D
M
A
E
E
V
T
-
E
L
S
----
L
D
R
L
S
D
-
S
Q
A
R
V
S
--
D
V
E
-
E
Q
V
N
Q
Y
----------------
L
S
V
P
E
L
E
Q
Q
N
V
S
E
L
L
S
L
L
S
N
-------
S
P
NISL
S
Q
L
A
Y
L
E
G
S
E
--
E
P
S
E
Q
F
M
L
C
-------
G
L
R
D
A
---------------------------------------
L
-
G
R
P
E
L
A
H
L
S
H
------------
L
-
V
E
Q
A
L
V
S
M
A
----
E
E
Q
G
E
T
I
V
L
G
A
R
I
T
P
E
A
Y
R
E
S
Q
-
S
G
V
-
N
P
L
Q
P
L
R
-
D
T
Y
----
R
D
A
V
M
G
Y
Q
G
I
Y
A
I
W
S
D
------
L
Q
--
R
F
P
N
G
D
I
D
S
V
I
L
F
L
Q
--
A
L
S
A
D
L
Q
S
Q
Q
S
G
-------------------
S
G
R
E
L
G
I
V
I
S
-----------------
D
L
Q
L
-
E
F
-------------------------------
6
PsiBlast_PDB
54.46
27%
13
- C1 -
4ZXQ
1
NEEDL_BPP22
A:
[67-139]
------------------------
N
D
E
Q
D
-
V
E
L
A
----
D
H
E
A
R
I
-
K
Q
L
R
I
D
V
D
D
H
E
-
S
R
I
T
A
N
----------------
T
K
A
I
T
A
L
N
V
R
V
T
T
A
E
G
E
I
A
S
-------
L
Q
----
T
N
V
S
A
L
D
G
R
V
--
T
T
A
E
N
N
I
S
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
54.19
27%
19
- C1 -
3C9I
4
NEEDL_BPP22
A:
[72-144]
------------------------
N
D
E
Q
D
-
V
E
L
A
----
D
H
E
A
R
I
-
K
Q
L
R
I
D
V
D
D
H
E
-
S
R
I
T
A
N
----------------
T
K
A
I
T
A
L
N
V
R
V
T
T
A
E
G
E
I
A
S
-------
L
Q
----
T
N
V
S
A
L
D
G
R
V
--
T
T
A
E
N
N
I
S
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
53.87
27%
17
- C1 -
4ZKP
2
NEEDL_BPP22
A:
[67-139]
------------------------
N
D
E
Q
D
-
V
E
L
A
----
D
H
E
A
R
I
-
K
Q
L
R
I
D
V
D
D
H
E
-
S
R
I
T
A
N
----------------
T
K
A
I
T
A
L
N
V
R
V
T
T
A
E
G
E
I
A
S
-------
L
Q
----
T
N
V
S
A
L
D
G
R
V
--
T
T
A
E
N
N
I
S
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
53.55
27%
18
- C1 -
2POH
-
NEEDL_BPP22
A:
[63-135]
------------------------
N
D
E
Q
D
-
V
E
L
A
----
D
H
E
A
R
I
-
K
Q
L
R
I
D
V
D
D
H
E
-
S
R
I
T
A
N
----------------
T
K
A
I
T
A
L
N
V
R
V
T
T
A
E
G
E
I
A
S
-------
L
Q
----
T
N
V
S
A
L
D
G
R
V
--
T
T
A
E
N
N
I
S
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
53.20
27%
18
- C1 -
4ZKU
2
NEEDL_BPP22
A:
[67-139]
------------------------
N
D
E
Q
D
-
V
E
L
A
----
D
H
E
A
R
I
-
K
Q
L
R
I
D
V
D
D
H
E
-
S
R
I
T
A
N
----------------
T
K
A
I
T
A
L
N
V
R
V
T
T
A
E
G
E
I
A
S
-------
L
Q
----
T
N
V
S
A
L
D
G
R
V
--
T
T
A
E
N
N
I
S
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
53.12
27%
21
- C1 -
4LIN
2
NEEDL_BPP22
A:
[74-146]
------------------------
N
D
E
Q
D
-
V
E
L
A
----
D
H
E
A
R
I
-
K
Q
L
R
I
D
V
D
D
H
E
-
S
R
I
T
A
N
----------------
T
K
A
I
T
A
L
N
V
R
V
T
T
A
E
G
E
I
A
S
-------
L
Q
----
T
N
V
S
A
L
D
G
R
V
--
T
T
A
E
N
N
I
S
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
46.30
11%
25
- C1 -
3A7O
-
ATG16_YEAST
A:
[60-118]
----------------------
H
D
D
A
L
L
N
T
L
A
I
L
----
Q
K
E
L
K
S
-
K
E
Q
E
I
R
--
R
L
K
-
E
V
I
A
L
K
----------------
N
K
N
T
E
R
L
N
D
E
L
I
S
G
T
I
E
N
N
V
-------
L
Q
----
Q
K
L
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
44.30
13%
26
- C1 -
1X8Y
-
LMNA_HUMAN
A:
[313-386]
------------
L
A
A
K
E
A
K
L
R
D
L
E
D
S
L
A
R
E
R
D
T
S
----
R
R
L
L
A
E
-
K
E
R
E
M
A
--
E
M
R
-
A
R
M
Q
Q
Q
----------------
L
D
E
Y
Q
E
L
L
D
I
K
L
A
L
D
M
E
I
H
A
-------
Y
R
----
K
L
L
E
G
E
E
E
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
43.18
17%
38
- C1 -
2P22
1
A:
[120-154]
-------------------
L
V
A
Q
D
Y
A
L
T
D
T
I
E
C
L
----
S
R
M
L
H
R
-
G
T
I
P
L
D
--
T
F
V
-
K
Q
G
R
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
42.74
18%
31
- C1 -
2F6M
3
STP22_YEAST
A:
[12-45]
--------------------
V
A
Q
D
Y
A
L
T
D
T
I
E
A
L
----
S
R
M
L
H
R
-
G
T
I
P
L
D
--
T
F
V
-
K
Q
G
R
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
HHSearch
42.53
18%
20
- C1 -
4MAK
1
CAS2_ECOLI
A:
[19-74]
--
L
A
I
W
L
L
E
V
R
-
A
G
V
Y
V
G
--
D
V
S
A
K
I
R
E
M
I
W
E
Q
I
----
A
G
L
A
E
E
-
G
N
V
V
M
A
---
W
A
-
T
N
T
E
T
G
----------------
F
E
F
Q
T
F
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
41.37
13%
23
- C1 -
4KE2
-
ANPM_PSEAM
A:
[0-195]
--
M
N
I
---
D
P
A
-
A
R
A
A
A
A
A
A
A
S
K
A
A
V
T
A
A
D
A
A
A
A
----
A
A
T
I
A
A
-
S
A
A
S
V
A
--
A
A
T
-
A
A
D
D
A
A
----------------
A
S
I
A
T
I
N
A
A
S
A
A
A
K
S
I
A
A
A
A
-------
A
M
----
A
A
K
D
T
A
A
A
A
A
--
S
A
A
A
A
A
V
A
S
-------
A
A
K
A
L
E
T
I
---------------------------------------------------------------------------------------------------------------
N
V
----
K
A
A
Y
A
A
A
T
T
A
N
T
A
A
A
A
------
A
A
A
T
A
T
T
A
A
A
A
A
A
A
K
A
T
I
D
--
N
A
A
A
A
K
A
A
A
V
A
T
A
V
S
D
-------
A
A
A
T
A
A
T
A
A
A
V
A
A
A
T
L
E
A
-----------------
A
A
A
K
-
A
A
A
T
A
V
S
-
A
A
A
A
A
A
A
A
A
I
A
F
A
A
A
P
---------
28
Fugue
41.13
7%
30
- C1 -
1IC2
-
TPM1_CHICK
A:
[1-79]
--------
M
D
A
-
I
K
K
K
M
Q
M
L
K
L
D
K
E
N
A
L
D
R
A
E
Q
A
----
E
A
D
K
K
A
-
A
E
E
R
S
K
--
Q
L
E
-
D
E
L
V
A
L
----------------
Q
K
K
L
K
G
T
E
D
E
L
D
K
Y
S
E
S
L
K
D
-------
A
Q
----
E
K
L
E
L
A
D
K
K
A
--
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
40.07
9%
3
- C3 -
4YVQ
-
HEM11_ARATH
A:
[439-527]
----------
M
-
L
E
T
V
P
T
I
K
K
L
R
A
Y
A
E
R
I
R
V
A
E
L
----
E
K
C
M
S
K
M
G
D
D
I
N
K
--
K
T
T
-
R
A
V
D
D
L
----------------
S
R
G
I
V
N
R
F
L
H
G
P
M
Q
H
L
R
C
R
T
-------
L
S
----
E
T
L
E
N
M
H
A
L
N
--
R
M
Y
G
L
E
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
40.05
27%
53
- C1 -
2XF7
-
?
A:
[22-47]
-------------------------------
E
L
L
----
R
V
A
V
N
A
-
G
D
L
T
Q
E
--
E
A
D
-
K
I
M
S
Y
P
----------------
W
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------