@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv0061: (2016-04-19 )
MCADAQPSGSVGLLGRNCPTATTRWRRAGEGLTAADTIEVKLWAGKPRLHPLVPKRAVGVLLAVAHGQVAKTPSATRAIAFRHVRLMRVRWICAGNRGRKHKRRCTTQYRSTQASKLQLHFKLRQTLNRLGGLQAMVSACG
Atome Classification :
(20 SA)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------...-------......10........20........30.....--------...40-..-----.......50-.-..-.-----------------....60-----..---.....-------.-.70........80..--.-----------..--...--------90....----..-----..100....--...110.-----...----------...120..-------.-----------....130.......140----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------MCA-------DAQPSGSVGLLGRNCPT
A
T
T
R
W
R
RAGEGLTA
A
D
--------
T
I
E
V
--
K
L
-----
W
AGKPRLHP-L-V
P
-
K
-----------------
R
A
V
G
V
------
L
L
---AVAHG-------Q-VAKTPS
A
T
R
A
I
A
F
R
H
--
V
-----------
R
L
--
M
R
V
--------
R
W
I
C
AG----NR-----GR
K
H
K
R
R
C
T
--
T
Q
YRSTQ-----A
S
K
----------
L
Q
L
H
F
K
L
R
-------
Q
-----------
T
L
N
R
LG
G
L
Q
A
M
V
S
ACG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
92.33
21%
-46
- C3 -
1K45
-
?
A:
[1-168]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
M
L
V
ANINGGF
E
S
T
P
A
G
V
V
T
D
L
A
E
G
V
E
G
W
D
L
N
V
---
G
S
S
V
T
N
P
P
--------
V
F
E
V
--
L
E
-----
T
S
D
A
P
E
G
N
K
-
V
-
L
A
-
V
-----------------
T
V
N
G
V
GNNPWD
I
E
---
A
T
A
F
P
-------
V
N
V
R
P
G
V
T
Y
T
Y
T
I
W
A
R
A
--
E
-----------
Q
D
--
G
A
V
--------
V
S
F
T
V
G
----
N
Q
SFQEY
G
R
L
H
E
Q
Q
I
T
--
T
E
W
Q
P
F
T
-----
F
E
F
T
VSDQET
V
I
R
A
P
I
H
F
G
Y
A
-------
A
-----------
N
V
G
N
T
I
Y
I
D
G
L
A
I
A
S
Q
P----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
87.58
20%
-39
- C5 -
3J6V
-
RT10_BOVIN
J:
[1-201]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
V
R
A
V
F
G
A
L
G
R
R
L
W
Q
G
S
K
N
F
S
V
S
S
S
R
S
N
I
A
K
--------
N
D
G
F
--
L
L
STSMK
W
V
Q
F
S
N
L
H
V
-
D
-
V
P
-
K
DLTKPTITISDEPDTLY
K
R
L
S
V
------
L
V
---
K
G
H
D
K
-------
A
-
V
L
D
S
Y
E
Y
F
A
V
L
A
A
K
E
--
L
GISVKVHEPPR
K
I
--
E
R
F
--------
T
L
L
K
S
V
----
H
I
-----
F
K
K
H
R
V
Q
Y
E
MR
T
L
Y
R
C
L
E
LEHLT
G
S
T
----------
A
D
V
Y
L
E
Y
I
-------
Q
RNLPEGVAMEV
T
K
T
R
L
E
Q
L
P
E
H
I
K
K
P
V
WETTPEEKGDSKS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
73.85
15%
-34
* C6 *
4PLO
-
B:
[1-204]
-----------------------------------------------------------------------------------------------------------------------------------GADESQVPDQPS
S
L
H
V
R
P
Q
TN
C
I
I
M
S
W
T
P
P
L
N
P
-------
N
I
V
V
R
G
Y
I
I
G
Y
G
V
G
S
P
Y
A
E
T
V
R
V
D
S
K
Q
R
Y
Y
S
I
E
R
L
E
S
S
S
H
Y
V
I
S
L
--
K
A
-----
F
N
N
A
G
E
G
V
P
-
L
-
Y
E
-
S
-----------------
A
T
T
R
S
------
I
T
---
D
V
S
T
P
M
L
P
P
V
G
V
Q
-
A
V
A
L
T
H
E
A
V
R
V
S
W
A
D
NS
V
-----------
R
L
--
Y
T
V
--------
R
W
R
T
S
S
----
A
K
-----
Y
K
S
E
D
T
T
S
L
--
S
Y
T
A
T
G
L
-----
K
P
N
----------
T
M
Y
E
F
S
V
M
-------
V
-----------
T
K
N
R
R
S
S
T
W
S
M
T
A
H
A
T
T
Y
EA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
73.73
17%
-51
- C2 -
4D2I
2
HERA_SULSO
A:
[1-476]
MII
G
Y
V
I
G
QATTQ
E
A
L
I
L
A
E
R
P
V
R
L
G
T
Y
V
V
L
E
Y
DNVK
A
L
G
L
I
T
N
V
T
R
G
S
PLLDDNMND
I
E
I
V
Q
R
L
K
Q
F
NNS
I
P
V
Y
T
K
A
K
V
K
L
L
CDMNNHFLMPD
I
P
P
F
AGT
P
A
R
E
A
E
D
E
E
L
K
S
I
YSQDGQIRIGSLIGKN
V
E
V
K
L
N
INSFAR
H
L
A
I
L
A
A
TGSG
K
S
N
T
V
A
V
L
S
Q
R
-------
I
S
E
L
G
G
S
V
L
I
F
D
Y
H
G
E
Y
Y
D
S
D
I
K
------------------------
N
L
-----
N
R
I
E
P
K
L
N
P
-
L
Y
M
T
-
P
-----------------
R
E
F
S
T
------
L
L
---------------
E
-
I
R
E
N
A
I
I
Q
Y
R
I
L
R
R
A
--
F
-----------
I
K
--
V
T
N
--------
G
I
R
A
A
L
----
A
A
-----
G
Q
I
P
F
S
T
L
N
--
S
Q
F
Y
E
L
M
-----
A
D
A
----------
L
K
-----
D
-------
E
-----------
V
L
N
K
F
E
E
F
M
D
R
Y
S
N
V
I
DLTSSDIIEKVKRGKV
N
V
V
S
LTQLD
E
D
S
M
D
A
V
V
S
H
Y
L
R
R
I
L
D
S
R
K
D
F
K
R
SKNSGLK
F
P
I
I
A
V
I
E
E
A
H
V
F
L
SKNENT
L
T
K
Y
W
A
S
R
I
A
R
EGRKFG
V
G
L
T
I
V
S
QRPKGLD
E
N
I
L
S
Q
MTNKIILKIIE
P
T
D
K
K
Y
I
L
E
S
S
DNLS
E
D
L
A
E
Q
L
SSLDVG
E
A
I
I
I
G
KIVKLPAVVKIDMFE
G
K
L
L
G
SDPDMIG
19
Fugue
70.88
14%
-38
- C5 -
2XL4
2
LNTA_LISMO
A:
[26-172]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
-------
P
K
L
S
T
K
D
L
A
L
I
K
A
D
L
A
E
F
E
A
R
E
L
S
S
E
K
I
L
K
D
T
I
--------
K
E
E
S
WS
D
L
-----
D
F
A
N
D
N
I
N
Q
M
I
-
G
T
M
K
-----------------
R
Y
Q
Q
E
------
I
L
S
I
D
A
I
K
R
A
-------
S
-
E
A
S
A
D
T
E
A
F
K
K
I
F
K
E
--
W
-----------
S
E
--
F
K
I
--------
E
R
I
Q
V
T
I
D
L
L
N
G
-----
K
K
D
S
E
A
V
F
K
--
K
T
Y
P
N
Q
I
-----
I
F
K
----------
K
V
R
T
N
K
L
Q
-------
T
-----------
A
L
N
N
L
K
V
G
Y
E
L
L
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
63.45
16%
-19
- C5 -
1BM9
-
RTP_BACSU
A:
[3-122]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
K
R
S
S
T
G
F
L
V
K
Q
R
A
F
L
K
L
Y
M
I
T
M
T
E
------------------------------
Q
E
R
L
Y
G
-
L
-----------------------
K
L
L
E
------
V
L
---
R
S
E
F
K
-------
E
-
I
G
F
K
P
N
H
T
E
V
Y
R
S
L
H
--
E
-----------
L
L
D
D
G
I
L
--------
K
Q
I
K
V
K
----
K
E
-----
G
A
K
L
Q
E
V
V
L
--
Y
Q
F
K
D
Y
E
-----
A
A
K
----------
L
Y
K
K
Q
L
K
V
-------
E
-----------
L
D
R
C
K
K
L
I
E
K
A
L
S
D
N
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
56.03
16%
-54
- C6 -
2COV
-
3XYN_ALCSP
D:
[378-469]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
P
-------
E
-
N
C
Q
D
D
F
N
F
N
Y
V
S
D
Q
E
--
I
-----------
E
V
--
Y
H
V
DKGWSAGW
N
Y
V
C
L
N
DYC-
L
P
-----
G
N
K
S
N
G
A
F
R
--
K
T
F
N
A
V
L
-----
G
Q
D
----------
Y
K
L
T
F
K
V
E
DRYGQGQ
Q
-----------
I
L
D
R
N
I
T
F
T
T
Q
V
--
C
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
53.76
22%
-11
- C5 -
1JDQ
-
Y983_THEMA
A:
[20-60]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
-------
K
Y
Q
V
T
K
T
L
D
V
R
G
E
V
C
P
V
P
D
V
E
T
K
R
A
L
Q
N
M
K
P
G
E
--------
I
L
E
V
--
W
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
35.57
26%
27
- C5 -
1LLM
-
EGR1_MOUSE (first)
C:
[66-84]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
----------
L
S
K
N
Y
H
L
E
-------
N
-----------
E
V
A
R
L
K
K
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
35.11
17%
81
* C5 *
2M0E
1
A:
[1-29]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
H
K
C
P
H
--
C
D
K
K
F
N
Q
-----
V
G
N
----------
L
K
A
H
L
K
I
H
-------
I
-----------
A
D
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
29.66
48%
39
- C5 -
3V4B
1
MAND_CELJU
A:
[98-140]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
R
R
G
P
V
G
M
T
A
L
A
--------
A
I
D
V
--
A
L
-----
W
D
I
K
A
K
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
29.29
48%
44
- C5 -
3V3W
2
MAND_CELJU
A:
[98-127]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
R
R
G
P
V
G
M
T
A
L
A
--------
A
I
D
V
--
A
L
-----
W
D
I
K
A
K
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
27.64
26%
44
- C5 -
2N30
-
?
A:
[2-24]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
D
L
P
N
F
G
--------
H
I
Q
V
--
K
V
-----
F
N
H
G
E
H
I
H
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
24.90
33%
84
- C4 -
2GI4
-
?
A:
[2-16]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
I
--------
L
F
I
C
L
G
----
N
I
-----
C
R
S
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
19.54
25%
121
- C4 -
1JL3
1
ARSC_BACSU
A:
[3-18]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
--
K
I
I
--------
Y
F
L
C
T
G
----
N
S
-----
C
R
S
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
16.40
33%
101
- C4 -
4PIC
1
PAP_GEOSE
A:
[3-17]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
R
I
--------
L
F
V
C
T
G
----
N
T
-----
C
R
S
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
14.87
35%
91
- C4 -
2CWD
-
?
A:
[4-20]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
--
V
R
V
--------
L
F
V
C
L
G
----
N
I
-----
C
R
S
P
M
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
14.66
31%
113
- C4 -
3JVI
1
?
A:
[4-21]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
--
M
K
L
--------
L
F
V
C
L
G
----
N
I
-----
C
R
S
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
HHSearch
12.99
27%
118
- C4 -
2L17
-
ARSC_SYNY3
A:
[1-15]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
--
K
K
V
--------
M
F
V
C
K
R
----
N
S
-----
C
R
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
12.34
24%
111
- C4 -
2FEK
-
WZB_ECOLI
A:
[1-16]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
F
--
N
N
I
--------
L
V
V
C
V
G
----
N
I
-----
C
R
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------