@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv0068: (2016-04-19 )
MTKWTAADIPDQTGRTAVITGANTGLGFETAAALAAHGAHVVLAVRNLDKGKQAAARITEATPGAEVELQELDLTSLASVRAAAAQLKSDHQRIDLLINNAGVMYTPRQTTADGFEMQFGTNHLGHFALTGLLIDRLLPVAGSRVVTISSVGHRIRAAIHFDDLQWERRYRRVAAYGQAKLANLLFTYELQRRLAPGGTTIAVASHPGVSNTEVVRNMPRPLVAVAAILAPLMQDAELGALPTLRAATDPAVRGGQYFGPDGFGEIRGYPKVVASSAQSHDEQLQRRLWAVSEELTGVVYPVG
Atome Classification :
(20 SA)
.........10........20........30........40........-------------50------------........60........70........--80........-90........100..-----...---------..110.--...-----...120.......130........140--........150.......160....-.-..170...--....180.----......190..-----...-..200........210.......220-.----------.-------.----------..-----...230.......240.......250-........260.......270.......280.......290.......300.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MTKWTAADIPDQTG
R
T
A
V
I
TGANTGL
G
F
E
T
A
A
A
L
A
AHG
A
H
V
V
L
A
V
RNLD-------------K
G
------------
K
Q
A
A
A
R
I
TEATPG
A
E
V
E
L
QEL
D
L
T
S
L
A
S
--
V
R
A
A
A
A
Q
L
KS-DH
Q
R
I
D
L
L
INNA
G
V
M
-----YTP---------RQTTAD--G
F
E
-----
M
QFGTN
H
L
G
H
F
A
L
T
-
G
L
L
I
D
R
L
LPV-A--G
S
R
V
V
T
ISSVG
H
R
I
R
A
A
I
HFD
D
L
Q
W
-
E
-
R
R
Y
R
R
V
A
A--Y
G
Q
A
K
L
A
N
----
L
L
F
T
Y
E
L
Q
R
RL-----APG-G
T
T
I
-
A
V
ASHPGVS
N
T
E
V
V
R
NMP
R
P
--
L
----------
V
-------
A
----------
V
A
-----
A
I
L
A
P
L
M
QDAELGALPTLRAATDPA--VRGGQYFGPDG
F
G
EIRG
Y
P
K
V
V
A
SSAQ
S
H
D
E
Q
L
Q
R
R
L
W
A
V
S
E
EL
T
G
V
VYPVG
115
HHSearch
87.31
48%
-79
- C2 -
3RD5
2
?
A:
[4-290]
-
T
G
W
T
A
A
D
L
P
S
F
A
Q
R
T
V
V
I
T
G
A
N
S
G
L
G
A
V
T
A
R
E
L
A
R
R
G
A
T
V
I
M
A
V
R
D
T
R
-------------
K
G
------------
E
A
A
A
R
T
M
-----
A
G
Q
V
E
V
R
E
L
D
L
Q
D
L
S
S
--
V
R
R
F
A
D
G
V
-----
S
G
A
D
V
L
I
N
N
A
G
I
M
-----
A
V
P
---------
Y
A
L
T
V
D
--
G
F
E
-----
S
Q
I
G
T
N
H
L
G
H
F
A
L
T
-
N
L
L
L
P
R
L
T
-------
D
R
V
V
T
V
S
S
M
A
H
W
P
-
G
R
I
N
L
E
D
L
N
W
-
R
S
R
R
Y
S
P
W
L
A
--
Y
S
Q
S
K
L
A
N
----
L
L
F
T
S
E
L
Q
R
R
L
-----
T
A
A
G
S
P
L
R
-
A
L
A
A
H
P
G
Y
S
H
T
N
L
----------------------------------------------------
A
T
D
A
D
F
G
A
R
Q
T
L
Y
A
A
S
Q
D
L
---
P
G
D
S
F
V
G
P
R
F
G
Y
--
L
G
R
T
Q
P
V
G
R
S
R
R
A
K
D
A
G
M
A
A
A
L
W
A
L
S
E
Q
L
T
K
T
E
F
P
--
1
PsiBlast_PDB
87.24
47%
-82
- C2 -
3RD5
2
?
A:
[4-291]
-
T
G
W
T
A
A
D
L
P
S
F
A
Q
R
T
V
V
I
T
G
A
N
S
G
L
G
A
V
T
A
R
E
L
A
R
R
G
A
T
V
I
M
A
V
R
D
T
R
-------------
K
G
-------------
E
A
A
A
R
----
T
M
A
G
Q
V
E
V
R
E
L
D
L
Q
D
L
S
S
--
V
R
R
F
A
D
G
V
S
G
-----
A
D
V
L
I
N
N
A
G
I
M
-----
A
V
P
---------
Y
A
L
T
V
D
--
G
F
E
-----
S
Q
I
G
T
N
H
L
G
H
F
A
L
T
-
N
L
L
L
P
R
L
T
-------
D
R
V
V
T
V
S
S
M
A
H
-
W
P
G
R
I
N
L
E
D
L
N
W
R
S
-
R
R
Y
S
P
W
L
A
--
Y
S
Q
S
K
L
A
N
----
L
L
F
T
S
E
L
Q
R
R
L
-----
T
A
A
-
G
S
P
L
R
A
L
A
A
H
P
G
Y
S
H
T
N
L
----------------------------------------------------
A
T
D
A
D
F
G
A
R
Q
T
L
Y
A
A
S
Q
D
---
L
P
G
D
S
F
V
G
P
R
-
F
G
Y
L
-
G
R
T
Q
P
V
G
R
S
R
R
A
K
D
A
G
M
A
A
A
L
W
A
L
S
E
Q
L
T
K
T
E
F
P
L
-
126
HHSearch
60.87
24%
-73
- C2 -
2QQ5
-
DHRS1_HUMAN
A:
[4-256]
----------
P
M
N
G
Q
V
C
V
V
T
G
A
S
R
G
I
G
R
G
I
A
L
Q
L
C
K
A
G
A
T
V
Y
I
T
G
R
H
L
D
-------------
T
L
------------
R
V
V
A
Q
E
A
Q
S
L
--
G
G
Q
C
V
P
V
V
C
D
S
S
Q
E
S
E
--
V
R
S
L
F
E
Q
V
D
R
E
Q
Q
G
R
L
D
V
L
V
N
N
A
Y
A
G
-----
V
Q
T
I
L
N
T
RNKAF
W
E
T
P
A
S
--
M
W
D
-----
D
I
N
N
V
G
L
R
G
H
Y
F
C
S
-
V
Y
G
A
R
L
M
V
P
A
-
G
--
Q
G
L
I
V
V
I
S
S
P
G
S
L
Q
----------------
Y
M
F
N
V
P
--
Y
G
V
G
K
A
A
C
----
D
K
L
A
A
D
C
A
H
E
L
-----
R
R
H
--
G
V
S
-
C
V
S
L
W
P
G
I
V
Q
T
E
L
L
-------------------------------------------------
S
S
A
E
T
T
E
L
S
G
K
C
V
V
A
L
A
T
D
P
N
IL
S
L
S
G
K
V
L
P
S
C
------------------------------------------
124
HHSearch
59.19
26%
-69
* C2 *
4URF
9
?
A:
[2-244]
----------
L
L
E
G
K
T
A
L
V
T
G
A
G
N
G
I
G
R
T
I
A
L
T
Y
A
A
E
G
A
N
V
V
V
S
D
I
S
D
E
-------------
W
G
------------
R
E
T
L
A
L
I
E
G
K
--
G
G
K
A
V
F
Q
H
A
D
T
A
H
P
E
D
--
H
D
E
L
I
A
A
A
K
R
-
A
F
G
R
L
D
I
A
C
N
N
A
G
I
S
-----
G
E
F
TPT------
A
E
T
T
D
A
--
Q
W
Q
-----
R
V
I
G
I
N
L
S
G
V
F
Y
G
V
-
R
A
Q
I
R
A
M
L
E
T
-
G
--
G
G
A
I
V
N
I
S
S
I
A
G
Q
I
---------------
G
I
E
G
I
T
P
--
Y
T
A
A
K
H
G
V
----
V
G
L
T
K
T
V
A
W
E
Y
-----
G
S
K
--
G
I
R
-
I
N
S
V
G
P
A
F
I
N
T
T
L
V
Q
N
V
P
L
E
--
T
----------
R
-------
R
----------
Q
L
E
Q
---
M
H
A
L
R
R
L
G
E
T
E
E
V
A
N
L
V
A
W
L
S
S
D
K
A
S-
F
V
T
G
S
Y
Y
A
V
D
G
G
----------------------------------------
41
PsiBlast_CBE
58.47
32%
-83
- C3 -
2JAP
2
?
B:
[7-192]
-------------
G
K
V
A
L
I
T
G
A
S
S
G
I
G
E
A
T
A
R
A
L
A
A
E
G
A
A
V
A
I
A
A
R
R
V
E
-------------
K
L
------------
R
A
L
G
D
E
L
T
A
A
--
G
A
K
V
H
V
L
E
L
D
V
A
D
R
Q
G
--
V
D
A
A
V
A
S
T
V
E
-
A
L
G
G
L
D
I
L
V
N
N
A
G
I
M
-----
L
L
G
---------
P
V
E
D
A
D
T
T
D
W
T
-----
R
M
I
D
T
N
L
L
G
L
M
Y
M
T
-
R
A
A
L
P
H
L
L
R
S
-
K
--
G
T
-
V
V
Q
M
S
S
I
A
G
R
V
N
V
---------------
R
N
A
A
V
--
Y
Q
A
T
K
F
G
V
----
N
A
F
S
E
T
L
R
Q
E
V
-----
T
E
R
-
G
V
R
V
-
V
V
I
E
-
P
G
T
T
D
T
E
L
-----------------------------------------------------------------------------------------------------------------------------
42
PsiBlast_CBE
58.45
32%
-82
- C3 -
2JAP
2
?
A:
[7-192]
-------------
G
K
V
A
L
I
T
G
A
S
S
G
I
G
E
A
T
A
R
A
L
A
A
E
G
A
A
V
A
I
A
A
R
R
V
E
-------------
K
L
------------
R
A
L
G
D
E
L
T
A
A
--
G
A
K
V
H
V
L
E
L
D
V
A
D
R
Q
G
--
V
D
A
A
V
A
S
T
V
E
-
A
L
G
G
L
D
I
L
V
N
N
A
G
I
M
-----
L
L
G
---------
P
V
E
D
A
D
T
T
D
W
T
-----
R
M
I
D
T
N
L
L
G
L
M
Y
M
T
-
R
A
A
L
P
H
L
L
R
S
-
K
--
G
T
-
V
V
Q
M
S
S
I
A
G
R
V
N
V
---------------
R
N
A
A
V
--
Y
Q
A
T
K
F
G
V
----
N
A
F
S
E
T
L
R
Q
E
V
-----
T
E
R
-
G
V
R
V
-
V
V
I
E
-
P
G
T
T
D
T
E
L
-----------------------------------------------------------------------------------------------------------------------------
40
PsiBlast_CBE
57.93
32%
-80
- C3 -
2JAP
2
?
C:
[7-192]
-------------
G
K
V
A
L
I
T
G
A
S
S
G
I
G
E
A
T
A
R
A
L
A
A
E
G
A
A
V
A
I
A
A
R
R
V
E
-------------
K
L
------------
R
A
L
G
D
E
L
T
A
A
--
G
A
K
V
H
V
L
E
L
D
V
A
D
R
Q
G
--
V
D
A
A
V
A
S
T
V
E
-
A
L
G
G
L
D
I
L
V
N
N
A
G
I
M
-----
L
L
G
---------
P
V
E
D
A
D
TT
D
W
T
-----
R
M
I
D
T
N
L
L
G
L
M
Y
M
T
-
R
A
A
L
P
H
L
L
R
S
-
K
--
G
T
-
V
V
Q
M
S
S
I
A
G
R
V
N
V
---------------
R
N
A
A
V
--
Y
Q
A
T
K
F
G
V
----
N
A
F
S
E
T
L
R
Q
E
V
-----
T
E
R
-
G
V
R
V
-
V
V
I
E
-
P
G
T
T
D
T
E
L
-----------------------------------------------------------------------------------------------------------------------------
39
PsiBlast_CBE
57.52
32%
-81
- C3 -
2JAP
2
?
D:
[7-192]
-------------
G
K
V
A
L
I
T
G
A
S
S
G
I
G
E
A
T
A
R
A
L
A
A
E
G
A
A
V
A
I
A
A
R
R
V
E
-------------
K
L
------------
R
A
L
G
D
E
L
T
A
A
--
G
A
K
V
H
V
L
E
L
D
V
A
D
R
Q
G
--
V
D
A
A
V
A
S
T
V
E
-
A
L
G
G
L
D
I
L
V
N
N
A
G
I
M
-----
L
L
G
---------
P
V
E
D
A
D
TT
D
W
T
-----
R
M
I
D
T
N
L
L
G
L
M
Y
M
T
-
R
A
A
L
P
H
L
L
R
S
-
K
--
G
T
-
V
V
Q
M
S
S
I
A
G
R
V
N
V
---------------
R
N
A
A
V
--
Y
Q
A
T
K
F
G
V
----
N
A
F
S
E
T
L
R
Q
E
V
-----
T
E
R
-
G
V
R
V
-
V
V
I
E
-
P
G
T
T
D
T
E
L
-----------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
56.09
29%
-83
- C3 -
4BMV
1
?
A:
[6-190]
---------------
T
V
L
I
T
G
A
S
S
G
I
G
A
T
Y
A
E
R
F
A
R
R
G
H
D
L
V
L
V
A
R
D
K
V
-------------
R
L
------------
D
A
L
A
A
R
L
R
D
E
S
-
G
V
A
V
E
A
L
Q
A
D
L
T
R
P
A
D
--
L
A
A
V
E
I
R
L
R
E
-
D
A
-
R
I
G
I
L
I
N
N
A
G
M
A
-----
Q
S
G
GF-------
V
Q
Q
T
A
E
--
G
I
E
-----
R
L
I
T
L
N
T
T
A
L
T
R
L
A
-
A
A
V
A
P
R
F
V
Q
S
-
G
--
T
G
A
I
V
N
I
G
S
V
---
V
G
F
A
P
E
F
G
------------
M
S
I
--
Y
G
A
T
K
A
F
V
----
L
F
L
S
Q
G
L
N
L
E
L
-----
S
P
S
-
G
I
Y
V
-
Q
-
A
V
L
P
A
A
T
R
T
E
I
-----------------------------------------------------------------------------------------------------------------------------
118
HHSearch
55.15
28%
-74
- C2 -
3TZQ
1
?
B:
[7-250]
---------
A
E
L
E
N
K
V
A
I
I
T
G
A
C
G
G
I
G
L
E
T
S
R
V
L
A
R
A
G
A
R
V
V
L
A
D
L
P
E
T
-------------
D
L
------------
A
G
A
A
A
S
V
-----
G
R
G
A
V
H
H
V
V
D
L
T
N
E
V
S
--
V
R
A
L
I
D
F
T
I
D
-
T
F
G
R
L
D
I
V
D
N
N
A
A
H
S
-----
D
P
A
DMLV-----
T
Q
M
T
V
D
--
V
W
D
-----
D
T
F
T
V
N
A
R
G
T
M
L
M
C
-
K
Y
A
I
P
R
L
I
S
A
-
G
--
G
G
A
I
V
N
I
S
S
A
T
A
H
A
---------------
A
Y
D
M
S
T
A
--
Y
A
C
T
K
A
A
I
----
E
T
L
T
R
Y
V
A
T
Q
Y
-----
G
R
H
--
G
V
R
-
C
N
A
I
A
P
G
L
V
R
T
P
R
L
E
---
P
Q
--
P
----------
I
-------
V
D
---------
I
F
A
T
---
H
H
L
A
G
R
I
G
E
P
H
E
I
A
E
L
V
C
F
L
A
S
D
R
A
A-
F
I
T
G
Q
V
I
A
A
D
S
G
L
---------------------------------------
117
HHSearch
54.51
20%
-67
- C2 -
4ZA2
-
?
A:
[5-248]
--------
S
F
D
L
Q
G
K
V
A
L
I
T
G
C
D
T
G
L
G
Q
G
M
A
I
G
L
A
Q
A
G
C
D
I
V
G
V
N
I
V
E
P
-------------
K
--------------
D
T
I
E
K
V
T
A
L
--
G
R
R
F
L
S
L
T
A
D
M
S
N
V
S
G
--
H
A
E
L
V
E
K
A
V
A
-
E
F
G
H
V
D
I
L
V
N
N
A
G
I
I
-----
R
R
E
DA-------
I
E
F
S
E
K
--
N
W
D
-----
D
V
M
N
L
N
I
K
S
V
F
F
M
S
-
Q
T
V
A
R
Q
F
I
K
Q
G
K
--
G
G
K
I
I
N
I
A
S
M
L
S
F
Q
---------------
G
G
I
R
V
P
S
--
Y
T
A
S
K
S
A
V
----
M
G
V
T
R
L
M
A
N
E
W
-----
A
K
H
--
G
I
N
-
V
N
A
I
A
P
G
Y
M
A
T
N
N
T
Q
Q
L
R
A
D
--
E
E
R
--------
S
K
------
E
----------
I
L
D
----
R
I
P
A
G
R
W
G
L
P
Q
D
L
M
G
P
S
V
F
L
A
S
S
A
S
D-
Y
I
N
G
Y
T
I
A
V
D
G
-----------------------------------------
133
HHSearch
54.30
26%
-71
- C2 -
3WDS
4
?
A:
[7-258]
--------
I
F
D
L
S
G
R
K
A
I
V
T
G
G
S
K
G
I
G
A
A
I
A
R
A
L
D
K
A
G
A
T
V
A
I
A
D
L
D
V
M
-------------
A
A
------------
Q
A
V
V
A
G
L
E
-----
N
G
G
F
A
V
E
V
D
V
T
K
R
A
S
--
V
D
A
A
M
Q
K
A
I
D
-
A
L
G
G
F
D
L
L
C
A
N
A
G
V
S
-----
T
M
R
PA-------
V
D
I
T
D
E
--
E
W
D
-----
F
N
F
D
V
N
A
R
G
V
F
L
A
N
-
Q
I
A
C
R
H
F
L
A
S
N
T
--
K
G
V
I
V
N
T
A
S
L
A
A
K
V
---------------
G
A
P
L
L
A
H
--
Y
S
A
S
K
F
A
V
----
F
G
W
T
Q
A
L
A
R
E
M
-----
A
P
K
--
N
I
R
-
V
N
C
V
C
P
G
F
V
K
T
A
M
Q
E
R
E
I
I
W
--
E
A
E
L
R
GMT
P
E
A
V
R
------
A
E
---------
Y
V
S
----
L
T
P
L
G
R
I
E
E
P
E
D
V
A
D
V
V
V
F
L
A
S
D
A
A
R-
F
M
T
G
Q
G
I
N
V
T
G
-----------------------------------------
130
HHSearch
53.88
24%
-73
- C2 -
2CFC
2
HCDR_XANP2
A:
[2-245]
-------------
S
R
V
A
I
V
T
G
A
S
S
G
N
G
L
A
I
A
T
R
F
L
A
R
G
D
R
V
A
A
L
D
L
S
A
E
-------------
T
L
------------
E
E
T
A
R
T
H
W
H
A
Y
-
A
D
K
V
L
R
V
R
A
D
V
A
D
E
G
D
--
V
N
A
A
I
A
A
T
M
E
-
Q
F
G
A
I
D
V
L
V
N
N
A
G
I
T
-----
G
N
S
EAGVL----
H
T
T
P
V
E
--
Q
F
D
-----
K
V
M
A
V
N
V
R
G
I
F
L
G
C
-
R
A
V
L
P
H
M
L
L
Q
-
G
--
A
G
V
I
V
N
I
A
S
V
A
S
L
V
---------------
A
F
P
G
R
S
A
--
Y
T
T
S
K
G
A
V
----
L
Q
L
T
K
S
V
A
V
D
Y
-----
A
G
S
--
G
I
R
-
C
N
A
V
C
P
G
M
I
E
T
P
M
T
Q
W
R
L
D
Q
P
E
L
----------
R
D
------
Q
----------
V
L
A
----
R
I
P
Q
K
E
I
G
T
A
A
Q
V
A
D
A
V
M
F
L
A
G
E
D
A
T-
Y
V
N
G
A
A
L
V
M
D
G
-----------------------------------------
5
PsiBlast_PDB
53.66
27%
-73
- C3 -
4NBU
1
?
A:
[14-204]
--------------
K
V
A
I
I
T
G
A
A
N
G
I
G
L
E
A
A
R
V
F
M
K
E
G
A
K
V
V
I
A
D
F
N
E
A
-------------
A
G
------------
K
E
A
----
V
E
A
N
P
G
--
V
V
F
I
R
V
D
V
S
D
R
E
S
--
V
H
R
L
V
E
N
V
A
E
-
R
F
G
K
I
D
I
L
I
N
N
A
G
I
T
-----
R
D
S
ML-------
S
K
M
T
V
D
--
Q
F
Q
-----
Q
V
I
N
V
N
L
T
G
V
F
H
C
T
-
Q
A
V
L
P
Y
M
A
E
Q
-
G
--
K
G
K
I
I
N
T
S
S
V
----------------
T
-
G
T
Y
G
N
V
G
Q
T
N
Y
A
A
A
K
A
G
V
----
I
G
M
T
K
T
W
A
K
E
L
-----
A
R
K
-
G
I
N
V
-
N
-
A
V
A
P
G
F
T
E
T
A
M
V
A
E
V
P
E
K
--
V
----------
I
--------------------------------------------------------------------------------------------------------
134
HHSearch
53.48
21%
-66
- C2 -
3TSC
1
?
A:
[7-272]
---------
G
K
L
E
G
R
V
A
F
I
T
G
A
A
R
G
Q
G
R
A
H
A
V
R
M
A
A
E
G
A
D
I
I
A
V
D
I
A
G
K
LPSCVP
Y
D
P
A
S
P
D
D
L
------------
S
E
T
V
R
L
V
E
A
A
--
N
R
R
I
V
A
A
V
V
D
T
R
D
F
D
R
--
L
R
K
V
V
D
D
G
V
A
-
A
L
G
R
L
D
I
I
V
A
N
A
G
V
A
-----
A
P
Q
A
W-------
D
D
I
T
P
E
--
D
F
R
-----
D
V
M
D
I
N
V
T
G
T
W
N
T
V
-
M
A
G
A
P
R
I
I
E
G
G
R
--
G
G
S
I
I
L
I
S
S
A
A
G
M
K
---------------
M
Q
P
F
M
I
H
--
Y
T
A
S
K
H
A
V
----
T
G
L
A
R
A
F
A
A
E
L
-----
G
K
H
--
S
I
R
-
V
N
S
V
H
P
G
P
V
N
T
P
M
G
S
G
D
M
V
T
--
A
----------
V
G
Q
A
M
E
T
N
P
QLSH------
V
L
T----
P
F
L
P
D
W
V
A
E
P
E
D
I
A
D
T
V
C
W
L
A
S
D
E
S
R-
K
V
T
A
A
Q
I
P
V
D
Q
-----------------------------------------
49
PsiBlast_CBE
51.38
32%
-82
- C3 -
3GY0
1
?
A:
[11-199]
--------------
R
I
I
L
V
T
G
A
S
D
G
I
G
R
E
A
A
M
T
Y
A
R
Y
G
A
T
V
I
L
L
G
R
N
E
E
-------------
K
L
------------
R
Q
V
A
S
H
I
N
E
E
T
-
G
R
Q
P
Q
W
F
I
L
D
L
L
T
C
T
S
E
N
C
Q
Q
L
A
Q
R
I
V
V
-
N
Y
P
R
L
D
G
V
L
H
N
A
G
L
L
-----
G
D
V
---------
C
P
M
S
E
Q
--
N
P
Q
V
W
Q
D
V
M
Q
I
N
V
N
--
A
T
F
M
L
T
Q
A
L
L
P
L
L
L
K
S
D
-
A
--
G
S
L
V
F
T
S
S
S
V
G
R
Q
G
R
A
-------
N
W
---------
G
A
--
Y
A
A
S
K
F
A
T
E
G
M
M
Q
V
L
A
D
E
Y
Q
Q
R
L
R
V
N
C
I
N
P
G
-
G
T
R
T
-
A
M
----------------------------------------------------------------------------------------------------------------------------------------
129
HHSearch
51.07
24%
-68
- C2 -
4G81
2
?
D:
[4-249]
--------
L
F
D
L
T
G
K
T
A
L
V
T
G
S
A
R
G
L
G
F
A
Y
A
E
G
L
A
A
A
G
A
R
V
I
L
N
D
I
R
A
T
-------------
L
L
------------
A
E
S
V
D
T
L
T
R
K
--
G
Y
D
A
H
G
V
A
F
D
V
T
D
E
L
A
--
I
E
A
A
F
S
K
L
D
A
-
E
G
I
H
V
D
I
L
I
N
N
A
G
I
Q
-----
Y
R
K
PM-------
V
E
L
E
L
E
--
N
W
Q
-----
K
V
I
D
T
N
L
T
S
A
F
L
V
S
-
R
S
A
A
K
R
M
I
A
R
N
S
--
G
G
K
I
I
N
I
G
S
L
T
S
Q
A
---------------
A
R
P
T
V
A
P
--
Y
T
A
A
K
G
G
I
----
K
M
L
T
C
S
M
A
A
E
W
-----
A
Q
F
--
N
I
Q
-
T
N
A
I
G
P
G
Y
I
L
T
D
M
N
T
A
L
I
E
D
--
K
Q---------
F
DS-----
W
----------
V
K
S----
S
T
P
S
Q
R
W
G
R
P
E
E
L
I
G
T
A
I
F
L
S
S
K
A
S
D-
Y
I
N
G
Q
I
I
Y
V
D
G
-----------------------------------------
48
PsiBlast_CBE
49.98
32%
-79
* C3 *
3GZ4
1
?
A:
[15-203]
--------------
R
I
I
L
V
T
G
A
S
D
G
I
G
R
E
A
A
M
T
Y
A
R
Y
G
A
T
V
I
L
L
G
R
N
E
E
-------------
K
L
------------
R
Q
V
A
S
H
I
N
E
E
T
-
G
R
Q
P
Q
W
F
I
L
D
L
L
T
C
T
S
E
D
C
Q
Q
L
A
Q
R
I
A
V
-
N
Y
P
R
L
D
G
V
L
H
N
A
G
L
L
GDVCP
M
S
E
---------
Q
D
P
Q
V
W
--
Q
D
V
-----
M
Q
V
N
V
N
--
A
T
F
M
L
T
Q
A
L
L
P
L
L
L
K
S
D
-
A
--
G
S
L
V
F
T
S
S
S
V
G
R
Q
G
R
A
-------
N
W
---------
G
A
--
Y
A
A
S
K
F
A
T
E
G
M
M
Q
V
L
A
D
E
Y
Q
Q
R
L
R
V
N
C
I
N
P
G
-
G
T
R
T
-
A
M
----------------------------------------------------------------------------------------------------------------------------------------
125
HHSearch
49.97
22%
-61
- C2 -
3PXX
1
?
A:
[3-282]
------
G
S
M
G
R
V
Q
D
K
V
V
L
V
T
G
G
A
R
G
Q
G
R
S
H
A
V
K
L
A
E
E
G
A
D
I
I
L
F
D
I
C
H
D
-------------
I
E
TNEYPLAT
S
R
D
L
E
E
A
G
L
E
V
E
K
T
--
G
R
K
A
Y
T
A
E
V
D
V
R
D
R
A
A
--
V
S
R
E
L
A
N
A
V
A
-
E
F
G
K
L
D
V
V
V
A
N
A
G
I
C
-----
P
L
G
---------
A
H
L
P
V
Q
--
A
F
A
-----
D
A
F
D
V
D
F
V
G
V
I
N
T
V
-
H
A
A
L
P
Y
L
T
S
-----
G
A
S
I
I
T
T
G
S
V
A
G
L
I
-
A
A
A
Q
P
P
--------
Q
G
P
G
G
A
G
--
Y
S
Y
A
K
Q
L
V
----
D
S
Y
T
L
Q
L
A
A
Q
L
-----
A
P
Q
--
S
I
R
-
A
N
V
I
H
P
T
N
V
N
T
D
M
L
N
S
A
P
M
Y
--
R
Q
F
--------
R
-------
P
DLEAPS
R
A
D
A
L
L
A
FPAM
Q
A
M
P
T
P
Y
V
E
A
S
D
I
S
N
A
V
C
F
L
A
S
D
E
S
R-
Y
V
T
G
L
Q
F
K
V
D
A
G
----------------------------------------
50
PsiBlast_CBE
49.91
31%
-101
- C3 -
4BMN
1
?
D:
[11-162]
--------------
K
T
A
V
I
T
G
G
N
S
G
I
G
L
A
T
A
K
R
F
V
A
E
G
A
Y
V
F
I
V
G
R
R
R
K
-------------
E
L
------------
E
Q
A
A
A
E
I
-----
G
R
N
V
T
A
V
K
A
D
V
T
K
L
E
D
--
L
D
R
L
Y
A
I
V
R
E
-
Q
R
G
S
I
D
V
L
F
A
N
S
G
A
I
EQ---
K
T
L
---------
E
E
I
T
P
E
--
H
Y
D
-----
R
T
F
D
V
N
V
R
G
L
I
-----
F
T
V
Q
K
A
L
P
L
-
L
RD
G
G
S
V
I
L
T
S
S
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------