@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv0097: (2016-04-19 )
MTLKVKGEGLGAQVTGVDPKNLDDITTDEIRDIVYTNKLVVLKDVHPSPREFIKLGRIIGQIVPYYEPMYHHEDHPEIFVSSTEEGQGVPKTGAFWHIDYMFMPEPFAFSMVLPLAVPGHDRGTYFIDLARVWQSLPAAKRDPARGTVSTHDPRRHIKIRPSDVYRPIGEVWDEINRTTPPIKWPTVIRHPKTGQEILYICATGTTKIEDKDGNPVDPEVLQELMAATGQLDPEYQSPFIHTQHYQVGDIILWDNRVLMHRAKHGSAAGTLTTYRLTMLDGLKTPGYAA
Atome Classification :
(20 SA)
-.........10......-.-.20........---30........40.....-.-..50........60...-..-...70..-.......80........90........100.......110.......120.......130.......140.......150-----.......160...-..-..170--........180.......190.......200.......-210.......220.......230.......240.......250.......260..-..-...270.......280.......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-
M
T
L
K
V
KGEGLG
A
Q
V
TGV-D-PKNLDDI
T
T
D
E
---
I
R
D
I
V
YTN
K
L
V
V
L
KDVH-P-
S
P
R
E
F
I
K
L
G
R
I
I
G
Q
I
VP-YY-EPMY-HH-EDHP
E
I
F
V
SSTEEGQGVPKTG
A
F
W
H
I
D
Y
M
FMPEPF
A
F
S
M
V
L
P
L
AVPGHDR
G
T
Y
F
I
D
L
A
R
V
W
Q
SLPAAKRDPARGTVSTHD-----PR
R
H
I
K
IR
P
S
D
V
Y
-
R
P
-
I
G
E
V
---
W
D
E
INRTTPPIKWPTVIRHPKTG
Q
E
I
L
Y
I
CATGT
T
K
I
E-DKDGNPV
D
P
E
V
L
Q
E
L
M
A
ATGQLDPEYQS
P
F
I
H
T
Q
H
Y
QVG
D
I
I
L
WDN
R
V
L
M
H
RAKH-GS-AAG
T
L
T
T
Y
R
L
T
M
LDGLKTPGYAA
5
PsiBlast_PDB
95.95
26%
-83
- C4 -
1GY9
4
TAUD_ECOLI
A:
[11-274]
-------
G
P
Y
I
G
A
Q
I
S
G
A
-
D
L
T
R
P
L
S
D
N
Q
F
E
Q
---
L
Y
H
A
V
L
R
H
Q
V
V
F
L
R
D
Q
A
-
I
-
T
P
Q
Q
Q
R
A
L
A
Q
R
F
G
E
L
---
H
I
-
H
P
V
Y
P
H
A
-
E
G
V
D
E
I
I
V
L
D
T
H
N
D
N
--
P
P
D
N
D
N
W
H
T
D
V
T
F
I
E
T
P
P
A
G
A
I
L
A
A
K
E
L
P
S
T
G
G
D
T
L
W
T
S
G
I
A
A
Y
E
A
L
S
V
P
F
R
Q
L
L
S
G
L
R
A
E
H
D
-----
F
R
K
S
F
---
P
E
Y
K
Y
-
R
K
-
T
E
E
E
H
Q
R
W
R
E
A
V
A
K
N
P
P
L
L
H
P
V
V
R
T
H
P
V
S
G
K
Q
A
L
F
V
N
E
G
F
T
T
R
I
V
-
D
V
S
E
K
--
E
S
E
A
L
L
S
F
L
F
A
-
H
I
T
K
P
E
F
Q
V
R
W
----
R
W
Q
P
N
D
I
A
I
W
D
N
R
V
T
Q
H
Y
A
N
A
-
D
Y
-
L
P
Q
R
R
I
M
H
R
A
T
I
L
----------
6
PsiBlast_PDB
95.27
26%
-86
- C4 -
1OS7
3
TAUD_ECOLI
A:
[11-274]
-------
G
P
Y
I
G
A
Q
I
S
G
A
-
D
L
T
R
P
L
S
D
N
Q
F
E
Q
---
L
Y
H
A
V
L
R
H
Q
V
V
F
L
R
D
Q
A
-
I
-
T
P
Q
Q
Q
R
A
L
A
Q
R
F
G
E
L
---
H
I
-
H
P
V
Y
P
H
A
-
E
G
V
D
E
I
I
V
L
D
T
H
N
D
N
--
P
P
D
N
D
N
W
H
T
D
V
T
F
I
E
T
P
P
A
G
A
I
L
A
A
K
E
L
P
S
T
G
G
D
T
L
W
T
S
G
I
A
A
Y
E
A
L
S
V
P
F
R
Q
L
L
S
G
L
R
A
E
H
D
-----
F
R
K
S
F
---
P
E
Y
K
Y
-
R
K
-
T
E
E
E
H
Q
R
W
R
E
A
V
A
K
N
P
P
L
L
H
P
V
V
R
T
H
P
V
S
G
K
Q
A
L
F
V
N
E
G
F
T
T
R
I
V
-
D
V
S
E
K
--
E
S
E
A
L
L
S
F
L
F
A
-
H
I
T
K
P
E
F
Q
V
R
W
----
R
W
Q
P
N
D
I
A
I
W
D
N
R
V
T
Q
H
Y
A
N
A
-
D
Y
-
L
P
Q
R
R
I
M
H
R
A
T
I
L
----------
7
PsiBlast_PDB
95.16
26%
-83
- C4 -
1OTJ
2
TAUD_ECOLI
A:
[11-274]
-------
G
P
Y
I
G
A
Q
I
S
G
A
-
D
L
T
R
P
L
S
D
N
Q
F
E
Q
---
L
Y
H
A
V
L
R
H
Q
V
V
F
L
R
D
Q
A
-
I
-
T
P
Q
Q
Q
R
A
L
A
Q
R
F
G
E
L
---
H
I
-
H
P
V
Y
P
H
A
-
E
G
V
D
E
I
I
V
L
D
T
H
N
D
N
--
P
P
D
N
D
N
W
H
T
D
V
T
F
I
E
T
P
P
A
G
A
I
L
A
A
K
E
L
P
S
T
G
G
D
T
L
W
T
S
G
I
A
A
Y
E
A
L
S
V
P
F
R
Q
L
L
S
G
L
R
A
E
H
D
-----
F
R
K
S
F
---
P
E
Y
K
Y
-
R
K
-
T
E
E
E
H
Q
R
W
R
E
A
V
A
K
N
P
P
L
L
H
P
V
V
R
T
H
P
V
S
G
K
Q
A
L
F
V
N
E
G
F
T
T
R
I
V
-
D
V
S
E
K
--
E
S
E
A
L
L
S
F
L
F
A
-
H
I
T
K
P
E
F
Q
V
R
W
----
R
W
Q
P
N
D
I
A
I
W
D
N
R
V
T
Q
H
Y
A
N
A
-
D
Y
-
L
P
Q
R
R
I
M
H
R
A
T
I
L
----------
4
PsiBlast_PDB
94.05
26%
-79
- C4 -
1GQW
3
TAUD_ECOLI
A:
[11-274]
-------
G
P
Y
I
G
A
Q
I
S
G
A
-
D
--
R
P
L
S
D
N
Q
F
E
Q
---
L
Y
H
A
V
L
R
H
Q
V
V
F
L
R
D
Q
A
-
I
-
T
P
Q
Q
Q
R
A
L
A
Q
R
F
G
E
L
---
H
I
-
H
P
V
Y
P
H
A
-
E
G
V
D
E
I
I
V
L
D
T
H
N
D
N
--
P
P
D
N
D
N
W
H
T
D
V
T
F
I
E
T
P
P
A
G
A
I
L
A
A
K
E
L
P
S
T
G
G
D
T
L
W
T
S
G
I
A
A
Y
E
A
L
S
V
P
F
R
Q
L
L
S
G
L
R
A
E
H
D
-----
F
R
K
S
F
---
P
E
Y
K
Y
-
R
K
-
T
E
E
E
H
Q
R
W
R
E
A
V
A
K
N
P
P
L
L
H
P
V
V
R
T
H
P
V
S
G
K
Q
A
L
F
V
N
E
G
F
T
T
R
I
V
-
D
V
S
E
K
--
E
S
E
A
L
L
S
F
L
F
A
-
H
I
T
K
P
E
F
Q
V
R
W
----
R
W
Q
P
N
D
I
A
I
W
D
N
R
V
T
Q
H
Y
A
N
A
-
D
Y
-
L
P
Q
R
R
I
M
H
R
A
T
I
L
----------
42
Fugue
93.03
25%
-77
- C4 -
1GY9
4
TAUD_ECOLI
A:
[4-282]
R
L
S
I
T
P
L
G
P
Y
I
G
A
Q
I
S
G
A
-
D
L
T
R
P
L
S
D
N
Q
F
E
Q
---
L
Y
H
A
V
L
R
H
Q
V
V
F
L
R
D
Q
A
-
I
-
T
P
Q
Q
Q
R
A
L
A
Q
R
F
G
E
L
-
H
-
I
H
-
P
V
Y
P
-
H
A
-
E
G
V
D
E
I
I
V
L
D
T
H
N
D
N
--
P
P
D
N
D
N
W
H
T
D
V
T
F
I
E
T
P
P
A
G
A
I
L
A
A
K
E
L
P
S
T
G
G
D
T
L
W
T
S
G
I
A
A
Y
E
A
L
S
V
P
F
R
Q
L
L
S
G
L
R
A
E
H
D
-----
F
R
K
S
F
P
E
Y
K
Y
R
K
T
-
E
E
-
E
H
Q
R
---
W
R
E
A
V
A
K
N
P
P
L
L
H
P
V
V
R
T
H
P
V
S
G
K
Q
A
L
F
V
N
E
G
F
T
T
R
I
V
-
D
V
S
-
E
K
E
S
E
A
L
L
S
F
L
F
A
H
I
T
K
------
P
E
F
Q
V
R
W
R
W
Q
P
N
D
I
A
I
W
D
N
R
V
T
Q
H
Y
A
N
A
-
D
Y
-
L
P
Q
R
R
I
M
H
R
A
T
I
L
G
--
D
K
P
F
Y
R
A
43
Fugue
91.89
25%
-78
- C4 -
1GQW
3
TAUD_ECOLI
A:
[4-282]
R
L
S
I
T
P
L
G
P
Y
I
G
A
Q
I
S
G
A
-
D
--
R
P
L
S
D
N
Q
F
E
Q
---
L
Y
H
A
V
L
R
H
Q
V
V
F
L
R
D
Q
A
-
I
-
T
P
Q
Q
Q
R
A
L
A
Q
R
F
G
E
L
H
I
-
H
--
P
V
Y
P
-
H
A
-
E
G
V
D
E
I
I
V
L
D
T
H
N
D
N
--
P
P
D
N
D
N
W
H
T
D
V
T
F
I
E
T
P
P
A
G
A
I
L
A
A
K
E
L
P
S
T
G
G
D
T
L
W
T
S
G
I
A
A
Y
E
A
L
S
V
P
F
R
Q
L
L
S
G
L
R
A
E
H
D
-----
F
R
K
S
F
P
E
Y
K
Y
R
K
T
-
E
E
-
E
H
Q
R
---
W
R
E
A
V
A
K
N
P
P
L
L
H
P
V
V
R
T
H
P
V
S
G
K
Q
A
L
F
V
N
E
G
F
T
T
R
I
V
-
D
V
S
-
E
K
E
S
E
A
L
L
S
F
L
F
A
H
I
------
T
K
P
E
F
Q
V
R
W
R
W
Q
P
N
D
I
A
I
W
D
N
R
V
T
Q
H
Y
A
N
A
-
D
Y
-
L
P
Q
R
R
I
M
H
R
A
T
I
L
G
--
D
K
P
F
Y
R
A
23
HHSearch
89.67
23%
-74
- C4 -
1OTJ
2
TAUD_ECOLI
A:
[5-282]
-
L
S
I
T
P
L
G
P
Y
I
G
A
Q
I
S
G
A
D
L
-
T
R
P
L
S
D
N
Q
F
E
Q
---
L
Y
H
A
V
L
R
H
Q
V
V
F
L
R
D
Q
A
-
I
-
T
P
Q
Q
Q
R
A
L
A
Q
R
F
G
E
L
H
I
-
H
P
-
V
Y
P
--
H
A
-
E
G
V
D
E
I
I
V
L
D
T
H
--
N
D
N
P
P
D
N
D
N
W
H
T
D
V
T
F
I
E
T
P
P
A
G
A
I
L
A
A
K
E
L
P
S
T
G
G
D
T
L
W
T
S
G
I
A
A
Y
E
A
L
S
V
P
F
R
Q
L
L
S
G
L
R
A
E
H
D
-----
F
R
K
S
F
P
E
Y
K
Y
R
K
T
E
E
E
-
H
Q
R
W
---
R
E
A
-
V
A
K
N
P
P
L
L
H
P
V
V
R
T
H
P
V
S
G
K
Q
A
L
F
V
N
E
G
F
T
T
R
I
V
-
D
V
S
E
K
E
S
-
E
A
L
L
S
F
L
F
A
H
I
T
K
------
P
E
F
Q
V
R
W
R
W
Q
P
N
D
I
A
I
W
D
N
R
V
T
Q
H
Y
A
N
A
-
D
Y
-
L
P
Q
R
R
I
M
H
R
A
T
I
L
G
D
K
P
F
Y
R
A
--
2
PsiBlast_PDB
87.33
24%
-81
- C4 -
3V15
-
?
A:
[3-272]
-
L
T
I
T
P
L
S
P
A
L
G
A
Q
I
S
G
V
-
D
I
S
R
D
I
S
A
E
E
R
D
A
---
I
E
Q
A
L
L
Q
H
Q
V
L
F
L
R
D
Q
P
-
I
-
N
P
E
Q
Q
A
R
F
A
A
R
F
G
D
L
---
H
I
-
H
P
I
Y
-
P
N
V
P
D
T
P
Q
V
L
V
L
D
T
A
V
T
D
V
--
R
D
N
A
V
W
H
T
D
V
T
F
L
P
T
P
A
L
G
A
V
L
S
A
K
Q
L
P
A
Y
G
G
D
T
L
W
A
S
G
I
A
A
F
E
A
L
S
A
P
L
R
E
M
L
D
G
L
T
A
T
H
D
FTKSF
P
L
E
R
F
G
T
T
P
Q
D
L
A
-
R
---------
W
E
A
T
R
R
N
N
P
P
L
S
H
P
V
V
R
T
H
P
V
S
G
R
K
A
L
F
V
N
E
G
F
T
T
R
I
N
-
E
L
--
S
E
L
E
S
D
A
L
L
R
L
L
F
A
H
A
T
-
R
P
E
F
S
I
R
W
----
R
W
Q
E
N
D
V
A
F
W
D
N
R
V
T
Q
H
F
A
V
D
-
D
Y
-
R
P
N
R
R
V
M
H
R
A
T
I
L
----------
1
PsiBlast_PDB
86.96
24%
-81
- C4 -
3PVJ
2
?
A:
[3-272]
-
L
T
I
T
P
L
S
P
A
L
G
A
Q
I
S
G
V
-
D
I
S
R
D
I
S
A
E
E
R
D
A
---
I
E
Q
A
L
L
Q
H
Q
V
L
F
L
R
D
Q
P
-
I
-
N
P
E
Q
Q
A
R
F
A
A
R
F
G
D
L
---
H
I
-
H
P
I
Y
-
P
N
V
P
D
T
P
Q
V
L
V
L
D
T
A
V
T
D
V
--
R
D
N
A
V
W
H
T
D
V
T
F
L
P
T
P
A
L
G
A
V
L
S
A
K
Q
L
P
A
Y
G
G
D
T
L
W
A
S
G
I
A
A
F
E
A
L
S
A
P
L
R
E
M
L
D
G
L
T
A
T
H
D
F
T
K
S
F
P
L
E
R
F
G
T
T
P
Q
D
L
A
-
R
---------
W
E
A
T
R
R
N
N
P
P
L
S
H
P
V
V
R
T
H
P
V
S
G
R
K
A
L
F
V
N
E
G
F
T
T
R
I
N
-
E
L
--
S
E
L
E
S
D
A
L
L
R
L
L
F
A
H
A
T
-
R
P
E
F
S
I
R
W
----
R
W
Q
E
N
D
V
A
F
W
D
N
R
V
T
Q
H
F
A
V
D
-
D
Y
-
R
P
N
R
R
V
M
H
R
A
T
I
L
----------
3
PsiBlast_PDB
86.94
24%
-79
- C4 -
3V17
1
?
A:
[3-272]
-
L
T
I
T
P
L
S
P
A
L
G
A
Q
I
S
G
V
-
D
I
S
R
D
I
S
A
E
E
R
D
A
---
I
E
Q
A
L
L
Q
H
Q
V
L
F
L
R
D
Q
P
-
I
-
N
P
E
Q
Q
A
R
F
A
A
R
F
G
D
L
---
H
I
-
H
P
I
Y
-
P
N
V
P
D
T
P
Q
V
L
V
L
D
T
A
V
T
D
V
--
R
D
N
A
V
W
H
T
D
V
T
F
L
P
T
P
A
L
G
A
V
L
S
A
K
Q
L
P
A
Y
G
G
D
T
L
W
A
S
G
I
A
A
F
E
A
L
S
A
P
L
R
E
M
L
D
G
L
T
A
T
H
D
F
T
K
S
F
P
L
E
R
F
G
T
T
P
Q
D
L
A
-
R
---------
W
E
A
T
R
R
N
N
P
P
L
S
H
P
V
V
R
T
H
P
V
S
G
R
K
A
L
F
V
N
E
G
F
T
T
R
I
N
-
E
L
--
S
E
L
E
S
D
A
L
L
R
L
L
F
A
H
A
T
-
R
P
E
F
S
I
R
W
----
R
W
Q
E
N
D
V
A
F
W
D
N
R
V
T
Q
H
F
A
V
D
-
D
Y
-
R
P
N
R
R
V
M
H
R
A
T
I
L
----------
22
HHSearch
85.12
19%
-89
- C4 -
4Y0E
3
?
A:
[38-310]
--
T
V
E
K
L
G
E
H
I
G
A
R
V
N
G
I
E
L
-
R
G
D
L
S
A
D
R
V
E
A
---
I
R
L
A
L
A
I
N
K
V
L
V
F
T
E
Q
H
H
L
-
D
D
A
G
Q
Y
A
F
A
R
L
L
G
E
P
T
L
P
H
P
-
T
V
----
R
-
S
H
G
T
E
L
L
---
N
-----
L
E
G
A
A
N
G
W
H
T
D
V
T
F
V
D
R
I
P
K
A
S
V
L
R
P
V
T
L
P
S
Y
G
G
A
T
T
W
A
S
T
V
A
A
Y
E
Q
L
P
K
P
L
R
S
L
V
D
D
L
W
A
T
H
T
-----
N
L
Y
D
-----------
E
R
R
A
A
Y
---
Y
T
E
F
T
S
S
R
Y
E
T
V
H
P
V
V
R
V
H
P
E
T
G
E
R
S
L
L
L
G
Q
F
-
V
K
S
F
Q
-
D
L
P
S
A
E
F
-
A
S
L
F
Q
L
L
Q
A
R
I
T
K
------
L
E
N
T
F
R
W
N
W
R
L
G
D
V
A
I
W
D
N
R
A
T
Q
H
Y
G
I
A
D
F
G
--
E
Q
Q
R
E
L
H
R
V
T
L
A
G
D
V
P
V
D
V
H
--
24
HHSearch
84.93
20%
-88
- C4 -
5HSX
12
?
A:
[20-302]
-
I
E
V
T
P
L
S
A
H
I
G
A
E
I
H
G
V
D
L
-
T
Q
K
L
E
A
R
Q
I
A
E
---
I
R
A
A
L
L
K
W
R
V
V
F
F
R
E
Q
F
-
L
-
T
H
E
Q
H
V
A
F
S
A
Q
F
G
E
L
T
L
G--V
F
G
---
H
V
-
E
G
H
P
E
V
Y
S
I
S
K
Y
--
Q
T
L
Q
R
P
W
T
G
W
H
T
D
V
T
A
A
V
N
P
P
W
A
S
I
L
R
G
V
T
I
P
P
Y
G
G
D
T
Q
W
T
N
L
V
A
A
Y
Q
K
L
S
A
P
L
R
S
F
V
D
G
L
R
G
I
H
R
-----
F
T
P
---------------------------
R
I
L
V
T
E
H
P
L
V
R
V
H
P
E
T
G
E
R
A
L
Y
V
S
P
S
F
L
K
S
I
V
-
G
V
S
P
R
E
S
-
Q
V
L
L
E
L
L
W
E
H
V
T
R
------
P
E
F
T
V
R
F
K
W
Q
A
G
S
V
A
F
W
D
N
R
A
T
A
H
L
A
P
T
D
I
F
D
L
D
F
D
R
Q
L
Y
R
T
T
L
V
G
D
V
P
V
G
P
D
--
21
HHSearch
84.54
23%
-76
- C4 -
3PVJ
2
?
A:
[4-277]
--
T
I
T
P
L
S
P
A
L
G
A
Q
I
S
G
V
D
I
-
S
R
D
I
S
A
E
E
R
D
A
---
I
E
Q
A
L
L
Q
H
Q
V
L
F
L
R
D
Q
P
-
I
-
N
P
E
Q
Q
A
R
F
A
A
R
F
G
D
L
H
I
-
H
P
-
I
Y
P
--
N
V
-
P
D
T
P
Q
V
L
V
L
D
T
A
--
V
T
D
V
R
D
N
A
V
W
H
T
D
V
T
F
L
P
T
P
A
L
G
A
V
L
S
A
K
Q
L
P
A
Y
G
G
D
T
L
W
A
S
G
I
A
A
F
E
A
L
S
A
P
L
R
E
M
L
D
G
L
T
A
T
H
D
-----
F
T
K
S
F
P
L
E
R
F
G
T
T
-
P
Q
D
L
A
R
W
---
E
A
T
-
R
R
N
N
P
P
L
S
H
P
V
V
R
T
H
P
V
S
G
R
K
A
L
F
V
N
E
G
F
T
T
R
I
N
-
E
L
S
E
L
E
S
-
D
A
L
L
R
L
L
F
A
H
A
T
R
------
P
E
F
S
I
R
W
R
W
Q
E
N
D
V
A
F
W
D
N
R
V
T
Q
H
F
A
V
D
D
Y
R
--
P
N
R
R
V
M
H
R
A
T
I
L
G
D
A
P
F
-----
26
HHSearch
82.34
21%
-91
- C4 -
4CVY
1
ATSK_MYCTU
A:
[6-280]
--
T
V
K
K
L
G
S
R
I
G
A
Q
I
D
G
V
R
L
-
G
G
D
L
D
P
A
A
V
N
E
---
I
R
A
A
L
L
A
H
K
V
V
F
F
R
G
Q
H
Q
L
-
D
D
A
E
Q
L
A
F
A
G
L
L
G
T
P
I
----------------------------------
N
R
W
H
T
D
V
T
F
A
A
N
Y
P
A
A
S
V
L
R
A
V
S
L
P
S
Y
G
G
S
T
L
W
A
N
T
A
A
A
Y
A
E
L
P
E
P
L
K
C
L
T
E
N
L
W
A
L
H
T
-----
N
------------------------------
D
F
R
T
E
H
P
V
V
R
V
H
P
E
T
G
E
R
T
L
L
A
G
D
F
-
V
R
S
F
V
-
G
L
D
S
H
E
S
-
R
V
L
F
E
V
L
Q
R
R
I
T
M
------
P
E
N
T
I
R
W
N
W
A
P
G
D
V
A
I
W
D
N
R
A
T
Q
H
R
A
I
D
-
D
Y
-
D
D
Q
H
R
L
M
H
R
V
T
L
M
G
D
V
P
V
D
V
Y
G
-
9
PsiBlast_PDB
81.76
24%
-92
- C4 -
3R1J
4
?
A:
[9-259]
-
I
T
V
T
K
L
G
S
R
I
G
A
R
V
D
G
V
-
R
L
G
G
D
L
D
D
A
T
V
E
Q
---
I
R
R
A
L
L
T
H
K
V
I
F
F
R
H
Q
H
-
H
L
D
D
S
R
Q
L
E
F
A
R
L
L
G
T
P
I
G
---------------------------
A
T
R
-----
W
H
T
D
V
T
F
A
A
N
Y
P
A
A
S
I
L
R
A
V
T
L
P
S
Y
G
G
S
T
L
W
A
S
T
V
A
A
Y
Q
Q
L
P
E
P
L
R
H
L
T
E
N
L
W
A
L
H
T
-----
N
R
-------------------------
P
D
F
R
T
---
E
H
P
V
V
R
V
H
P
E
T
G
E
R
A
L
-
L
A
G
D
F
V
R
G
F
V
-
G
L
D
G
H
--
E
S
S
V
L
L
E
L
L
Q
R
R
I
T
M
-
P
E
N
T
V
R
W
----
S
W
A
P
G
D
V
A
M
W
D
N
R
A
T
Q
H
R
A
-----------------------------
10
PsiBlast_PDB
81.58
23%
-94
- C4 -
4FFA
-
ATSK_MYCTU
A:
[8-257]
-
I
T
V
K
K
L
G
S
R
I
G
A
Q
I
D
G
V
-
R
L
G
G
D
L
D
P
A
A
V
N
E
---
I
R
A
A
L
L
A
H
K
V
V
F
F
R
G
Q
H
-
Q
L
D
D
A
E
Q
L
A
F
A
G
L
L
G
T
P
I
----------------------------------
N
R
W
H
T
D
V
T
F
A
A
N
Y
P
A
A
S
V
L
R
A
V
S
L
P
S
Y
G
G
S
T
L
W
A
N
T
A
A
A
Y
A
E
L
P
E
P
L
K
C
L
T
E
N
L
W
A
L
H
T
-----
N
R
-------------------------
P
D
F
R
T
---
E
H
P
V
V
R
V
H
P
E
T
G
E
R
T
L
L
A
G
D
F
V
R
S
F
V
G
L
D
S
H
E
S
R
V
L
F
E
V
L
Q
R
R
I
T
M
-----
P
E
N
T
I
R
W
----
N
W
A
P
G
D
V
A
I
W
D
N
R
A
T
Q
H
R
A
-----------------------------
11
PsiBlast_PDB
81.17
23%
-93
- C4 -
4CVY
1
ATSK_MYCTU
A:
[5-254]
-
I
T
V
K
K
L
G
S
R
I
G
A
Q
I
D
G
V
-
R
L
G
G
D
L
D
P
A
A
V
N
E
---
I
R
A
A
L
L
A
H
K
V
V
F
F
R
G
Q
H
-
Q
L
D
D
A
E
Q
L
A
F
A
G
L
L
G
T
P
I
----------------------------------
N
R
W
H
T
D
V
T
F
A
A
N
Y
P
A
A
S
V
L
R
A
V
S
L
P
S
Y
G
G
S
T
L
W
A
N
T
A
A
A
Y
A
E
L
P
E
P
L
K
C
L
T
E
N
L
W
A
L
H
T
-----
N
---------------------------
D
F
R
T
---
E
H
P
V
V
R
V
H
P
E
T
G
E
R
T
L
L
A
G
D
F
V
R
S
F
V
G
L
D
S
H
E
S
R
V
L
F
E
V
L
Q
R
R
I
T
M
-----
P
E
N
T
I
R
W
----
N
W
A
P
G
D
V
A
I
W
D
N
R
A
T
Q
H
R
A
-----------------------------
8
PsiBlast_PDB
80.47
23%
-101
- C4 -
5HSX
12
?
A:
[29-275]
----------
I
G
A
E
I
H
G
V
-
D
L
T
Q
K
L
E
A
R
Q
I
A
E
---
I
R
A
A
L
L
K
W
R
V
V
F
F
R
E
Q
F
-
L
-
T
H
E
Q
H
V
A
F
S
A
Q
F
G
E
L
T
L
-
G
---
V
F
G
-
H
V
-
E
G
H
P
E
V
Y
S
I
S
K
Y
--
Q
T
L
Q
R
P
W
T
G
W
H
T
D
V
T
A
A
V
N
P
P
W
A
S
I
L
R
G
V
T
I
P
P
Y
G
G
D
T
Q
W
T
N
L
V
A
A
Y
Q
K
L
S
A
P
L
R
S
F
V
D
G
L
R
G
I
H
-----------
R
F
T
P
---------------------
R
I
L
V
T
E
H
P
L
V
R
V
H
P
E
T
G
E
R
A
L
Y
V
S
P
S
F
L
K
S
I
V
-
G
V
--
S
P
R
E
S
Q
V
L
L
E
L
L
W
E
H
-
V
T
R
P
E
F
T
V
R
F
----
K
W
Q
A
G
S
V
A
F
W
D
N
R
A
T
A
H
L
A
-----------------------------
25
HHSearch
80.32
16%
-92
- C4 -
1OIH
1
ATSK_PSEPU
A:
[15-292]
-
L
D
V
H
P
V
A
G
R
I
G
A
E
I
R
G
V
K
L
-
S
P
D
L
D
A
A
T
V
E
A
---
I
Q
A
A
L
V
R
H
K
V
I
F
F
R
G
Q
T
H
L
-
D
D
Q
S
Q
E
G
F
A
K
L
L
G
E
P
V
A
------
P
--
V
V
-
D
G
T
R
Y
L
L
Q
L
D
---------
R
A
N
S
W
H
T
D
V
T
F
V
E
A
Y
P
K
A
S
I
L
R
S
V
V
A
P
A
S
G
G
D
T
V
W
A
N
T
A
A
A
Y
Q
E
L
P
E
P
L
R
E
L
A
D
K
L
W
A
V
H
S
-----
N
E
-----------------------------
V
Y
E
T
E
H
P
V
V
R
V
H
P
I
S
G
E
R
A
L
Q
L
G
H
F
-
V
K
R
I
K
-
G
Y
S
L
A
D
S
-
Q
H
L
F
A
V
L
Q
G
H
V
T
R
------
L
E
N
T
V
R
W
R
W
E
A
G
D
V
A
I
W
D
N
R
A
T
Q
H
Y
A
V
D
-
D
Y
-
G
T
Q
P
R
I
V
R
R
V
T
L
A
G
E
V
P
V
G
V
D
G
-
13
PsiBlast_PDB
80.05
20%
-82
- C4 -
4Y0E
3
?
A:
[37-283]
-
I
T
V
E
K
L
G
E
H
I
G
A
R
V
N
G
I
-
E
-
L
R
G
--
D
L
S
A
D
R
V
E
A
I
R
L
A
L
A
I
N
K
V
L
V
F
T
E
Q
H
-
H
L
D
D
A
G
Q
Y
A
F
A
R
L
L
G
--------
E
P
T
L
-----
P
H
P
T
V
R
S
H
G
T
E
L
-
L
N
L
E
G
A
A
N
G
W
H
T
D
V
T
F
V
D
R
I
P
K
A
S
V
L
R
P
V
T
L
P
S
Y
G
G
A
T
T
W
A
S
T
V
A
A
Y
E
Q
L
P
K
P
L
R
S
L
V
D
D
L
W
A
T
H
T
-----
N
L
Y
D
----------
E
R
-
R
A
A
Y
---
Y
T
E
F
T
S
S
R
Y
E
T
V
H
P
V
V
R
V
H
P
E
T
G
E
R
S
L
-
L
L
G
Q
F
V
K
S
F
Q
-
D
L
P
S
A
E
F
-
A
S
L
F
Q
L
L
Q
A
R
I
T
K
L
E
N
T
F
R
------
W
N
W
R
L
G
D
V
A
I
W
D
N
R
A
T
Q
H
-------------------------------