@TOME V2.3
(Nov 2016)
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
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Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv0102: (2016-04-19 )
MGTHGATKSATSAVPTPRSNSMAMVRLAIGLLGVCAVVAAFGLVSGARRYAEAGNPYPGAFVSVAEPVGFFAASLAGALCLGALIHVVMTAKPEPDGLIDAAAFRIHLLAERVSGLWLGLAATMVVIQAAHDTGVGPARLLASGALSDSVAASEMARGWIVAAICALVVATALRLYTRWLGHVVLLVPTVLAVVATAVTGNPGQGPDHDYATSAAIVFAVAFATLTGLKIAAALAGTTPSRAVLVTQVTCGALALAYGAMLLYLFIPGWAVDSDFARLGLLAGVILTSVWLFDCWRLLVRPPHAGRRRGGGSGAALAMMAAMASIAAMAVMTAPRFLTHAFTAWDVFLGYELPQPPTIARVLTVWRFDSLIGAAGVVLAIGYAAGFAALRRRGNSWPVGRLIAWLTGCAALVFTSGSGVRAYGSAMFSVHMAEHMTLNMFIPVLLVLGGPVTLALRVLPVTGDGRPPGAREWLTWLLHSRVTTFLSHPITAFVLFVASPYIVYFTPLFDTFVRYHWGHEFMAIHFLVVGYLFYWAIIGIDPGPRRLPYPGRIGLLFAVMPFHAFFGIALMTMSSTVGATFYRSVNLPWLSSIIADQHLGGGIAWSLTELPVIMVIVALVTQWARQDRRVASREDRHADSDYADDELEAYNAMLRELSRMRR
Atome Classification :
(16 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640-.......650.......660
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MGTHGATKSATSAVPTPRSN
S
M
A
M
V
R
L
A
I
G
L
L
G
V
C
A
V
V
A
A
F
G
L
V
S
G
A
R
R
Y
AEAGNPYPG
A
F
V
S
VA
E
P
V
G
F
F
A
A
S
L
A
G
A
L
C
L
G
A
L
I
H
V
V
MTAKPEPDG
L
I
D
A
A
A
F
R
I
H
L
L
A
E
R
V
S
G
L
W
L
G
L
A
A
T
M
V
V
IQAAHDTGV
G
P
A
R
L
L
A
SGALS
D
S
V
A
A
S
E
M
A
R
G
W
I
V
A
A
I
C
A
L
V
V
A
T
A
L
R
L
Y
T
R
W
L
G
H
V
V
L
L
V
P
T
V
L
A
V
V
A
T
AVTGNPGQGPDH
D
Y
A
T
S
A
A
I
V
F
A
V
A
F
A
T
LT
G
L
K
I
A
A
A
LAGTTP
S
R
A
V
L
V
T
QV
T
C
G
A
L
A
L
A
Y
G
A
M
L
L
Y
L
FIPGWAV
D
S
D
F
A
R
L
G
L
L
A
G
V
I
L
T
S
V
W
L
F
D
C
W
R
L
L
VRPPHAGRRRGGG
S
G
A
A
L
A
M
M
A
A
M
A
S
I
A
A
M
A
V
M
T
A
P
R
F
L
T
H
A
F
T
A
W
D
V
F
LGYELPQP
P
T
I
A
R
V
L
T
V
W
R
F
D
S
L
I
GA
A
G
V
V
L
A
I
G
Y
A
A
G
F
A
A
L
R
RRGNSW
P
V
G
R
L
I
A
W
L
T
G
C
A
A
L
V
FTSGS
G
V
R
A
Y
G
S
A
M
F
S
V
H
M
A
E
H
M
T
L
N
M
F
I
P
V
L
L
VLGG
P
V
T
L
A
L
R
V
L
P
VTGDGRPP
G
A
R
E
W
L
T
W
L
L
H
S
R
V
T
T
F
L
SH
P
I
T
A
F
V
L
F
VAS
P
Y
I
V
Y
F
T
P
L
F
D
T
F
V
R
Y
HWG
H
E
F
M
A
I
H
F
L
V
V
G
Y
L
F
Y
W
A
I
IGIDPGPRRLPYPGR
I
G
L
L
F
A
V
M
P
F
H
A
F
F
G
I
A
L
M
T
MSSTV
G
A
T
F
Y
RSVN
L
P
W
L
S
S
I
I
A
DQHLGGG
I
A
W
S
L
T
E
L
P
V
I
M
V
I
V
A
L
V
T
Q
W
A
R
Q
D
R
R
VASREDRHADSDYA-
D
D
E
L
E
A
Y
N
A
M
L
R
E
L
S
R
MRR-
13
Fugue
83.55
19%
306
- C4 -
2OQQ
-
HY5_ARATH
A:
[1-42]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
A
Y
L
S
E
L
E
N
R
V
K
D
L
E
N
K
N
S
E
L
E
E
R
-
L
S
T
L
Q
N
E
N
Q
M
L
R
H
I
L
K
N
---
17
Fugue
82.06
32%
484
* C4 *
3M91
-
PUP_MYCTU
B:
[21-51]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
T
A
A
G
Q
E
R
R
E
K
L
T
E
E
T
D
D
L
L
D
E
I
-
D
D
V
L
E
E
N
A
------------
9
Fugue
77.30
15%
289
- C4 -
3HE5
-
?
A:
[0-46]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
N
L
V
A
Q
L
E
N
E
V
A
S
L
E
N
E
N
E
T
L
K
K
K
N
L
H
-
K
K
D
L
I
A
Y
L
E
K
E
I
A
N
L
R
K
K
I
E
10
Fugue
75.88
16%
383
- C4 -
2BEQ
-
SPIKE_CVHSA
A:
[914-949]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
Q
I
Q
E
S
L
T
T
T
S
T
A
L
G
K
L
Q
D
V
V
-
N
Q
N
A
Q
A
L
N
T
L
V
K
Q
L
S
-----
14
Fugue
73.67
17%
135
- C4 -
2MH3
-
HES1_HUMAN
A:
[26-95]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
P
K
T
A
S
E
H
R
K
S
S
K
--
P
I
M
E
K
R
R
R
A
R
I
N
E
S
L
S
Q
L
K
T
L
I
L
D
A
L
K
K
D
S
S
R
H
S
K
L
E
K
-
A
D
I
L
E
M
T
V
K
H
L
R
N
L
Q
R
A
Q
--
15
Fugue
72.19
17%
414
- C4 -
4PAS
-
A:
[767-801]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
E
K
S
R
L
L
E
K
E
N
R
E
L
E
K
I
I
A
-
E
K
E
E
R
V
S
E
L
R
H
Q
L
Q
S
-----
12
Fugue
71.20
22%
382
- C4 -
3BJ4
1
KCNQ1_HUMAN
A:
[12-48]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
N
T
I
G
A
R
L
N
R
V
E
D
K
V
T
Q
L
D
Q
R
L
A
L
I
T
D
M
L
H
Q
L
L
S
L
H
G
-
11
Fugue
65.16
32%
530
- C4 -
3TWE
2
?
A:
[1-26]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
N
A
D
E
L
-
Y
K
E
L
E
D
L
Q
E
R
L
R
K
L
R
K
K
L
R
S
16
Fugue
60.19
17%
519
- C4 -
1COS
2
?
A:
[1-29]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
W
E
A
L
E
K
K
L
A
A
L
E
S
K
L
Q
A
L
E
K
K
-
L
E
A
L
E
H
G
-------------
8
Fugue
55.10
34%
587
- C4 -
2XZE
-
CHMP3_HUMAN
Q:
[18-40]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
E
D
E
-
E
E
E
E
E
A
L
E
A
M
Q
S
R
L
A
T
L
R
S
-
2
HHSearch
53.43
29%
983
- C4 -
4GIP
1
FUS_PIV5
A:
[47-60]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
T
S
I
S
S
Y
N
A
T
V
T
K
L
------
4
HHSearch
33.83
8%
468
- C4 -
4OGQ
14
PETG_NOSS1
G:
[5-28]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
S
G
I
V
L
G
L
I
V
V
T
L
A
G
L
F
Y
A
A
Y
K
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
HHSearch
33.39
8%
493
- C4 -
1Q90
3
PETG_CHLRE
G:
[5-28]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
C
G
I
V
L
G
L
V
P
V
T
I
A
G
L
F
V
T
A
Y
L
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
HHSearch
25.00
14%
2614
- C3 -
2L2T
-
ERBB4_HUMAN
A:
[57-63]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
I
G
G
L
F
I
----------------------------------------------------
5
HHSearch
21.02
8%
1597
- C2 -
4NUU
-
ACKR1_HUMAN
C:
[10-19]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
E
D
V
W
N
S
S
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
9.85
0%
3714
- C1 -
2MOF
-
LAMP2_HUMAN
A:
[395-400]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Y
F
I
G
L
---------------------------------------