@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv0109: (2016-04-19 )
MSLLITSPATVAAAATHLAGIGSALSTANAAAAAPTTALSVAGADEVSVLIAALFEAYAQEYQALSAQALAFHDQFVQALNMGAVCYAAAETANATPLQALQTVQQNVLTVVNAPTQALLGRPIIGNGANGLPNTGQDGGPGGLLFGNGGNGGSGGVDQAGGNGGAAGLIGNGGSGGVGGPGIAGSAGGAGGAGGLLFGNGGPGGAGGIGTTGDGGPGGAGGNAIGLFGSGGTGGMGGVGGMGGVGNGGNAGNGGTAGLFGHGGAGGAGGIGSADGGLGGGGGNGRFMGNGGVGGAGGYGASGDGGNAGNGGLGGVFGDGGAGGTGGLGDVNGGLAGIGGNAGFVRNGGAGGNGQLGSGAVSSAGGMGGNGGLVFGNGGPGGLGGPGTSAGNGGMGGNAVGLFGQGGAGGAGGSGFGAGIPGGRGGDGGSGGLIGDGGTGGGAGAGDAAASAGGNGGNARLIGNGGDGGPGMFGGPGGAGGSGGTIFGFAGTPGPS
Atome Classification :
(20 SA)
.........10........20........------30---.........40...--.....50...--.....60---..-.......70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
S
L
L
ITS
P
A
T
V
A
A
A
A
T
H
L
A
G
I
G
S
A
L
STAN------A----AAAAPT
T
A
L
S
VAG
A
--
D
E
V
S
V
L
I
A
A
L
--
F
E
A
Y
A
Q
----
E
Y
-
Q
A
L
S
A
Q
A
L
A
F
H
D
Q
F
V
Q
A
L
NMG
A
V
C
Y
AAAETANA
T
P
L
Q
A
L
Q
T
V
Q
Q
N
V
L
T
V
VNA
P
T
Q
A
LLGRPIIGNGANGLPNTGQDGGPG
G
L
L
FGNGGNGGSGGVDQAGGNGGAAGLIGNGGSGGVGGPGIAGSAGGAGGAGG
L
L
FGNGGPGGAGGIGTTGDGGPGGAGG
N
A
I
G
L
FGSGGTGGMGGVGGMGGVGNGGNAGNGGTAGLFGHGGAGGAGGIGSADGGLGGGGGNG
R
F
MGNGGVGGAGGYGASGDGGNAGNGGLGGVFGDGGAGGTGGLGDVNGGLAGIGGNA
G
F
VRNGGAGGNGQLGSGAVSSAGGMGGNG
G
L
V
FGNGGPGGLGGPGTSAGNGGMGGN
A
V
G
L
FGQGGAGGAGGSGFGAGIPGGRGGDGGSGGLIGDGGTGGGAGAGDAAASAGGNGG
N
A
R
L
I
GNGGDGGPGMFGGPGGAGGSG
G
T
I
F
G
FAGTPGPS
1
PsiBlast_PDB
82.68
36%
-123
- C3 -
4KXR
-
PE25_MYCTU
A:
[7-91]
------
N
P
E
A
L
T
V
A
A
T
E
V
R
R
I
R
D
R
A
I
Q
S
D
------
A
----
Q
V
A
P
M
T
T
A
V
R
P
P
A
A
--
D
L
V
S
E
K
A
A
T
F
--
L
V
E
Y
A
R
----
K
Y
R
Q
T
I
A
A
A
A
V
V
L
-
E
E
F
A
H
A
L
T
T
G
A
D
K
Y
A
T
A
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
78.68
35%
-136
- C3 -
4W4K
-
PE25_MYCTU
A:
[8-89]
-------
P
E
A
L
T
V
A
A
T
E
V
R
R
I
R
D
R
A
I
Q
S
D
------
A
----
Q
V
A
P
M
T
T
A
V
R
P
P
A
A
--
D
L
V
S
E
K
A
A
T
F
--
L
V
E
Y
A
R
----
K
Y
R
Q
T
I
A
A
A
A
V
V
L
-
E
E
F
A
H
A
L
T
T
G
A
D
K
Y
A
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
77.74
36%
-110
- C3 -
4W4L
-
PE25_MYCTU
A:
[7-90]
------
N
P
E
A
L
T
V
A
A
T
E
V
R
R
I
R
D
R
A
I
Q
S
D
------
A
----
Q
V
A
P
M
T
T
A
V
R
P
P
A
A
--
D
L
V
S
E
K
A
A
T
F
--
L
V
E
Y
A
R
----
K
Y
-
R
Q
T
I
A
A
A
A
V
V
L
E
E
F
A
H
A
L
T
T
G
A
D
K
Y
A
T
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
77.10
35%
-110
- C3 -
4W4L
-
PE25_MYCTU
A:
[7-90]
------
N
P
E
A
L
T
V
A
A
T
E
V
R
R
I
R
D
R
A
I
Q
S
D
------
A
----
Q
V
A
P
M
T
T
A
V
R
P
P
A
A
--
D
L
V
S
E
K
A
A
T
F
--
L
V
E
Y
A
R
----
K
Y
-
R
Q
T
I
A
A
A
A
V
V
L
E
E
F
A
H
A
L
T
T
G
A
D
K
Y
A
T
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
76.23
34%
-108
- C3 -
4KXR
-
PE25_MYCTU
A:
[7-91]
------
N
P
E
A
L
T
V
A
A
T
E
V
R
R
I
R
D
R
A
I
Q
S
D
------
A
----
Q
V
A
P
M
T
T
A
V
R
P
P
A
A
--
D
L
V
S
E
K
A
A
T
F
--
L
V
E
Y
A
R
----
K
Y
-
R
Q
T
I
A
A
A
A
V
V
L
E
E
F
A
H
A
L
T
T
G
A
D
K
Y
A
T
A
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
75.87
36%
-127
- C3 -
2G38
-
PE25_MYCTU
A:
[8-84]
-------
P
E
A
L
T
V
A
A
T
E
V
R
R
I
R
D
R
A
I
Q
S
D
------
A
----
Q
V
A
P
M
T
T
A
V
R
P
P
A
A
--
D
L
V
S
E
K
A
A
T
F
--
L
V
E
Y
A
R
----
K
Y
R
Q
T
I
A
A
A
A
V
V
L
-
E
E
F
A
H
A
L
T
T
G
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
70.76
32%
-120
- C3 -
4W4K
-
PE25_MYCTU
A:
[8-89]
-------
P
E
A
L
T
V
A
A
T
E
V
R
R
I
R
D
R
A
I
Q
S
D
------
A
----
Q
V
A
P
M
T
T
A
V
R
P
P
A
A
--
D
L
V
S
E
K
A
A
T
F
--
L
V
E
Y
A
R
----
K
Y
-
R
Q
T
I
A
A
A
A
V
V
L
E
E
F
A
H
A
L
T
T
G
A
D
K
Y
A
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
68.75
32%
-108
- C3 -
2G38
-
PE25_MYCTU
A:
[8-84]
-------
P
E
A
L
T
V
A
A
T
E
V
R
R
I
R
D
R
A
I
Q
S
D
------
A
----
Q
V
A
P
M
T
T
A
V
R
P
P
A
A
--
D
L
V
S
E
K
A
A
T
F
--
L
V
E
Y
A
R
----
K
Y
-
R
Q
T
I
A
A
A
A
V
V
L
E
E
F
A
H
A
L
T
T
G
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
65.22
18%
-119
- C3 -
3FAV
3
ESXB_MYCTU
A:
[12-85]
----------
L
A
Q
E
A
G
N
F
E
R
I
S
G
D
L
K
T
Q
I
------
D
----
Q
V
E
S
T
A
G
S
L
Q
G
Q
------
W
R
G
A
A
G
T
A
--
A
Q
A
A
V
V
----
R
F
-
Q
E
A
A
N
K
Q
K
Q
E
L
D
E
I
S
T
N
I
R
Q
A
G
V
Q
Y
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
59.78
18%
-110
- C3 -
2GMF
-
CSF2_HUMAN
A:
[4-124]
-----
R
S
P
S
P
S
T
Q
P
W
E
H
V
N
A
I
Q
E
A
R
R
L
L
N
------
L
S
R
D
T
A
A
E
M
N
E
T
V
E
V
I
S
E
M
FD
L
Q
E
P
T
C
L
Q
T
R
--
L
E
L
Y
K
Q
G
LRG
S
L
-
T
K
L
K
G
P
L
T
M
M
A
S
H
Y
K
Q
H
------
C
P
P
T
P
E
T
S
C
A
T
Q
I
I
T
F
E
S
F
K
E
N
L
K
D
F
L
L
V
I
P
F
D
C
W
E
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
47.68
17%
-100
- C3 -
1XOU
-
?
B:
[2-85]
-------------------------
G
I
V
S
------
Q
----
T
R
N
K
E
L
L
D
K
K
I
R
S
E
--
I
E
A
I
K
K
I
I
A
E
--
F
D
V
V
K
E
----
S
V
-
N
E
L
S
E
K
A
K
T
-
D
P
Q
A
A
E
K
L
N
K
L
I
E
G
Y
T
Y
G
E
E
R
K
L
Y
D
-
S
A
L
S
K
I
E
K
L
I
E
T
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
47.41
18%
-92
- C3 -
4LWS
5
?
A:
[35-127]
--
Q
S
A
V
D
R
A
A
M
A
Q
A
A
Q
D
I
E
Q
S
A
N
A
I
R
G
M
Q
------
N
----
Q
L
A
S
A
K
D
Q
L
R
S
------
H
W
E
G
D
A
S
M
A
--
F
E
A
V
F
N
----
R
F
-
N
E
D
F
S
R
V
L
K
A
L
D
G
M
H
E
S
L
V
Q
T
R
I
T
Y
E
A
R
E
E
A
A
Q
Q
S
V
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
45.45
13%
-99
- C3 -
3GWK
1
?
C:
[3-93]
M
S
Q
I
K
L
T
P
E
E
L
R
S
S
A
Q
K
Y
T
A
G
S
Q
Q
V
T
E
V
L
------
N
----
L
L
T
Q
E
Q
A
V
I
D
E
N
------
W
D
G
S
T
F
D
S
--
F
E
A
Q
F
N
----
E
L
-
S
P
K
I
T
E
F
A
Q
L
L
E
D
I
N
Q
Q
L
L
K
V
A
D
I
I
E
Q
T
D
A
D
I
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
45.16
22%
-99
- C3 -
3H6P
1
?
A:
[31-90]
----------------
A
F
A
A
K
A
G
L
M
R
H
T
I
------
G
----
Q
A
E
Q
Q
A
M
S
A
Q
A
------
F
H
Q
G
E
S
A
A
A
--
F
Q
G
A
H
A
----
R
F
-
V
A
A
A
A
K
V
N
T
L
L
D
I
A
Q
A
N
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
45.15
11%
-80
- C3 -
2FCW
5
A:
[1-106]
---------------------
G
A
E
F
E
E
P
R
------
V
----
I
D
L
W
D
L
A
Q
S
A
N
L
T
D
--
K
E
L
E
A
F
R
E
E
L
K
H
F
E
A
K
I
E
----
K
H
-
N
H
Y
Q
K
Q
L
E
I
A
H
E
K
L
R
H
A
E
S
V
G
D
G
E
R
V
S
R
S
R
E
K
H
A
L
L
E
G
R
T
K
E
L
G
Y
T
V
K
K
H
L
Q
D
L
S
G
R
I
S
R
A
R
H
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
43.99
17%
-98
- C3 -
4LWS
10
?
B:
[8-91]
S
D
Y
T
R
A
N
F
G
G
L
S
E
G
E
A
Q
F
S
M
T
A
R
A
L
L
D
E
L
------
T
----
D
L
E
G
K
L
R
A
K
L
------
D
R
W
D
G
D
A
Q
A
A
--
Y
W
N
Y
Q
K
----
E
W
-
D
A
A
A
K
D
M
Q
N
V
V
A
Q
L
G
V
A
I
R
E
A
H
D
N
Y
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
43.60
13%
-110
- C3 -
4WJ1
-
?
A:
[3-91]
-
E
E
L
Q
Y
E
L
P
G
L
E
R
K
A
H
E
C
E
S
T
R
--------------------
P
E
G
P
G
D
A
T
K
P
D
E
--
L
A
T
T
A
S
V
Y
S
K
--
L
M
A
S
A
A
----
K
L
-
K
A
T
F
A
A
G
D
R
E
G
E
R
I
A
A
A
I
R
A
A
A
G
A
Y
Q
K
I
E
E
Q
K
A
A
E
L
S
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
43.58
12%
-89
- C3 -
1EZJ
2
A:
[2-115]
-----
E
N
T
S
S
M
K
E
M
A
T
L
L
T
S
L
G
V
I
Q
S
A
Q
E
F
E
SSRD
A
----
S
Y
V
F
A
R
R
A
L
K
S
A
N
Y
--
A
E
M
T
F
N
V
C
G
L
--
I
L
S
A
E
K
----
S
S
-
A
R
K
V
D
E
N
K
Q
L
L
K
Q
I
Q
E
S
V
E
S
F
R
D
I
Y
K
R
F
S
E
Y
Q
K
E
Q
N
S
L
L
M
S
N
L
S
T
L
H
I
I
T
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
42.86
12%
-108
- C3 -
2VS0
4
ESXA_STAAM
A:
[3-85]
--
M
I
K
M
S
P
E
E
I
R
A
K
S
Q
S
Y
G
Q
G
S
D
Q
I
R
Q
I
L
------
S
----
D
L
T
R
A
Q
G
E
I
A
A
------
N
W
E
G
Q
A
F
S
R
--
F
E
E
Q
F
Q
----
Q
L
-
S
P
K
V
E
K
F
A
Q
L
L
E
E
I
K
Q
Q
L
N
S
T
A
D
A
V
Q
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
HHSearch
41.43
13%
-97
- C3 -
3ZBH
3
?
A:
[9-95]
-----
L
T
P
E
E
L
R
G
V
A
R
Q
Y
N
V
E
S
S
N
V
T
E
L
I
------
A
----
R
L
D
Q
M
S
H
T
L
Q
G
------
I
W
E
G
A
S
S
E
A
--
F
I
Q
Q
Y
Q
----
E
L
-
R
P
S
F
E
K
M
A
V
L
L
N
E
V
G
Q
Q
L
H
N
S
A
T
I
L
E
D
T
D
Q
Q
I
A
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------