@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv0124: (2016-04-19 )
MSFVSVAPEIVVAAATDLAGIGSAISAANAAAAAPTTAVLAAGADEVSAAIAALFSGHAQAYQALSAQAAAFHQQFVQTLAGGAGAYAAAEAQVEQQLLAAINAPTQALLGRPLIGNGADGAPGTGQAGGAGGILYGNGGNGGSGAAGQAGGAGGPAGLIGHGGSGGAGGSGAAGGAGGHGGWLWGNGGVGGSGGAGVGAGVAGGHGGAGGAAGLWGAGGGGGNGGNGADANIVSGGDGGLGGAGGGGGWLYGDGGAGGHGGQGAIGLGGGAGGDGGQGGAGRGLWGTGGAGGHGGQGGGTGGPPLPGQAGMGAAGGAGGLIGNGGAGGDGGVGASGGVAGVGGAGGNAMLIGHGGAGGAGGDSSFANGAAGGAGGAGGHLFGNGGSGGHGGAVTAGNTGIGGAGGVGGDARLIGHGGAGGAGGDRAGALVGRDGGPGGNGGAGGQLYGNGGDGAPGTGGTLQAAVSGLVTALFGAPGQPGDTGQPG
Atome Classification :
(20 SA)
.........10........20........30........40........50.....-...60........70........80..--...-----...90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MS
F
V
SVA
P
E
I
V
V
A
AA
T
D
L
A
GI
G
S
A
I
S
AANAAAAAPT
T
A
V
L
AA
G
A
D
E
V
S
A
A
I
A
A
L
FS-G
H
A
Q
A
Y
Q
A
L
S
A
Q
A
A
A
F
H
Q
Q
F
V
Q
T
LAGG--AGA-----
Y
A
A
A
E
A
Q
V
E
Q
Q
L
L
A
A
IN
A
P
T
Q
A
LLGRPLIGNGADGAPGTGQAGGAG
G
I
L
YGNGGNGGSGAAGQAGGAGGPAGLIGHGGSGGAGGSGAAGGAGGHGG
W
L
WGNGGVGGSGGAGVGAGVAGGHGGAGGAAGLWGAGGGGGNGGNGADA
N
I
VSGGDGGLGGAGGGGGWLYGDGGAGGHGGQG
A
I
GLGGGAGGDGGQGGAGRGLWGTGGAGGHGGQGGGTGGPPLPGQAGMGAAGGAGGLIGNGGAGGDGGVGASGGVAGVGGAGG
N
A
M
L
I
GHGGAGGAGGDSSFANGAAGGAGGAGGHLFGNGGSGGHG
G
A
V
TAGNTGIGGAGGVGGD
A
R
L
I
GHGGAGGAGGDR
A
G
A
LVGRDGGPGGNGGAGGQLYGNGGDGAPGTG
G
T
L
Q
A
A
V
S
G
L
V
T
A
L
FGAPGQPGDTGQPG
1
PsiBlast_PDB
80.53
38%
-100
- C1 -
4KXR
-
PE25_MYCTU
A:
[7-91]
------
N
P
E
A
L
T
V
A
A
T
E
V
R
R
I
R
D
R
A
I
Q
S
D
A
Q
V
A
P
M
T
T
A
V
R
P
P
A
A
D
L
V
S
E
K
A
A
T
F
L
V
-
E
Y
A
R
K
Y
R
Q
T
I
A
A
A
A
V
V
L
E
E
F
A
H
A
L
T
T
G
--
A
D
K
-----
Y
A
T
A
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
79.79
38%
-99
- C1 -
4W4L
-
PE25_MYCTU
A:
[7-90]
------
N
P
E
A
L
T
V
A
A
T
E
V
R
R
I
R
D
R
A
I
Q
S
D
A
Q
V
A
P
M
T
T
A
V
R
P
P
A
A
D
L
V
S
E
K
A
A
T
F
L
V
-
E
Y
A
R
K
Y
R
Q
T
I
A
A
A
A
V
V
L
E
E
F
A
H
A
L
T
T
G
--
A
D
K
-----
Y
A
T
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
79.18
37%
-99
- C1 -
4W4L
-
PE25_MYCTU
A:
[7-90]
------
N
P
E
A
L
T
V
A
A
T
E
V
R
R
I
R
D
R
A
I
Q
S
D
A
Q
V
A
P
M
T
T
A
V
R
P
P
A
A
D
L
V
S
E
K
A
A
T
F
L
V
-
E
Y
A
R
K
Y
R
Q
T
I
A
A
A
A
V
V
L
E
E
F
A
H
A
L
T
T
G
--
A
D
K
-----
Y
A
T
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
78.69
35%
-100
- C1 -
4KXR
-
PE25_MYCTU
A:
[7-91]
------
N
P
E
A
L
T
V
A
A
T
E
V
R
R
I
R
D
R
A
I
Q
S
D
A
Q
V
A
P
M
T
T
A
V
R
P
P
A
A
D
L
V
S
E
K
A
A
T
F
L
V
-
E
Y
A
R
K
Y
R
Q
T
I
A
A
A
A
V
V
L
E
E
F
A
H
A
L
T
T
G
--
A
D
K
-----
Y
A
T
A
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
77.22
36%
-104
- C1 -
4W4K
-
PE25_MYCTU
A:
[8-89]
-------
P
E
A
L
T
V
A
A
T
E
V
R
R
I
R
D
R
A
I
Q
S
D
A
Q
V
A
P
M
T
T
A
V
R
P
P
A
A
D
L
V
S
E
K
A
A
T
F
L
V
-
E
Y
A
R
K
Y
R
Q
T
I
A
A
A
A
V
V
L
E
E
F
A
H
A
L
T
T
G
--
A
D
K
-----
Y
A
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
76.03
34%
-104
- C1 -
4W4K
-
PE25_MYCTU
A:
[8-89]
-------
P
E
A
L
T
V
A
A
T
E
V
R
R
I
R
D
R
A
I
Q
S
D
A
Q
V
A
P
M
T
T
A
V
R
P
P
A
A
D
L
V
S
E
K
A
A
T
F
L
V
-
E
Y
A
R
K
Y
R
Q
T
I
A
A
A
A
V
V
L
E
E
F
A
H
A
L
T
T
G
--
A
D
K
-----
Y
A
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
74.04
38%
-103
- C1 -
2G38
-
PE25_MYCTU
A:
[8-84]
-------
P
E
A
L
T
V
A
A
T
E
V
R
R
I
R
D
R
A
I
Q
S
D
A
Q
V
A
P
M
T
T
A
V
R
P
P
A
A
D
L
V
S
E
K
A
A
T
F
L
V
-
E
Y
A
R
K
Y
R
Q
T
I
A
A
A
A
V
V
L
E
E
F
A
H
A
L
T
T
G
--
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
71.25
33%
-103
- C1 -
2G38
-
PE25_MYCTU
A:
[8-84]
-------
P
E
A
L
T
V
A
A
T
E
V
R
R
I
R
D
R
A
I
Q
S
D
A
Q
V
A
P
M
T
T
A
V
R
P
P
A
A
D
L
V
S
E
K
A
A
T
F
L
V
-
E
Y
A
R
K
Y
R
Q
T
I
A
A
A
A
V
V
L
E
E
F
A
H
A
L
T
T
G
--
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
66.96
19%
-131
- C1 -
4XXX
2
ESPB_MYCTU
A:
[3-108]
--
M
V
T
V
D
Q
Q
E
I
L
N
R
A
N
E
V
E
A
P
M
---------
A
D
P
P
T
D
V
P
I
T
P
C
E
L
T
A
A
K
N
A
A
Q
Q
L
V
-
L
S
A
D
N
M
R
E
Y
L
A
A
G
A
K
E
R
Q
R
L
A
T
S
L
R
N
A
--
A
K
A
-----
Y
G
E
V
D
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
Fugue
57.80
10%
-80
- C1 -
2WL8
-
PEX19_HUMAN
A:
[171-280]
----------------------
I
L
P
I
M
Q
S
I
M
Q
N
L
L
S
K
D
V
L
Y
P
S
L
K
E
I
T
E
K
Y
P
E
W
L
Q
-
S
H
R
E
S
L
P
P
E
Q
F
E
K
Y
Q
E
Q
H
S
V
M
C
K
I
C
E
Q
--
F
E
A
ETPTD
S
E
T
T
Q
K
A
R
F
E
M
V
L
D
L
M
Q
Q
L
Q
D
--
L
G
H
P
P
K
E
L
A
G
E
M
P
P
G
L
N
F
D
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
Fugue
57.18
14%
-96
- C1 -
1SET
-
SYS_THET2
A:
[1-110]
M
V
D
L
K
R
L
R
Q
E
P
E
V
F
H
R
A
I
R
E
K
G
V
A
L
D
L
E
A
L
L
A
L
D
R
E
V
Q
E
L
K
K
R
L
Q
E
V
Q
T
E
R
N
Q
V
A
K
-
R
V
P
K
A
P
P
E
E
K
E
A
L
I
A
R
G
K
A
L
G
E
E
A
K
R
L
--
E
E
A
-----
L
R
E
K
E
A
R
L
E
A
L
L
L
Q
V
P
L
P
P
W
P
G
A
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
54.58
13%
-108
- C1 -
3GWK
1
?
C:
[3-90]
M
S
Q
I
K
L
T
P
E
E
L
R
S
S
A
Q
K
Y
T
A
G
S
Q
Q
V
T
E
V
L
N
L
L
T
Q
E
Q
A
V
I
D
----
E
N
W
D
G
S
T
F
D
S
F
E
-
A
Q
F
N
E
L
S
P
K
I
T
E
F
A
Q
L
L
E
D
I
N
Q
Q
L
L
K
V
--
A
D
I
-----
I
E
Q
T
D
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
54.27
15%
-115
- C1 -
2VS0
4
ESXA_STAAM
A:
[3-85]
--
M
I
K
M
S
P
E
E
I
R
A
K
S
Q
S
Y
G
Q
G
S
D
Q
I
R
Q
I
L
S
D
L
T
R
A
Q
G
E
I
----
A
A
N
W
E
G
Q
A
F
S
R
F
E
-
E
Q
F
Q
Q
L
S
P
K
V
E
K
F
A
Q
L
L
E
E
I
K
Q
Q
L
N
S
T
--
A
D
A
-----
V
Q
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
Fugue
53.35
12%
-111
- C1 -
2GSC
-
?
A:
[9-125]
--
R
P
H
E
R
L
D
A
W
R
D
S
M
E
L
V
E
M
I
Y
R
L
T
E
V
F
P
D
Q
E
R
Y
G
L
T
A
Q
L
R
R
A
A
V
S
I
P
S
N
I
A
E
G
A
A
R
D
Y
S
R
F
L
S
I
A
R
G
S
L
S
E
L
D
T
Q
V
Q
I
A
A
R
L
G
YS
R
S
E
-----
D
D
Q
S
V
R
R
Q
V
D
L
V
F
A
K
L
T
A
L
M
N
A
L
R
R
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
52.06
30%
-100
- C1 -
4E72
-
?
A:
[86-141]
-----------------------------------------------------------------
L
P
A
S
L
A
A
Y
E
R
Q
F
L
D
S
A
E
P
G
--
W
S
S
-----
Y
L
Q
A
K
V
R
E
Q
H
D
G
L
V
I
I
E
------
L
S
S
Y
L
F
T
G
G
A
H
G
M
P
G
R
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
50.38
22%
-89
- C1 -
3H6P
1
?
A:
[31-90]
----------------
A
F
A
A
K
A
G
L
M
R
H
T
I
G
Q
A
E
Q
Q
A
M
S
A
----
Q
A
F
H
Q
G
E
S
A
A
A
F
Q
-
G
A
H
A
R
F
V
A
A
A
A
K
V
N
T
L
L
D
I
A
Q
A
N
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
50.06
14%
-99
- C1 -
3ZBH
3
?
A:
[9-91]
-----
L
T
P
E
E
L
R
G
V
A
R
Q
Y
N
V
E
S
S
N
V
T
E
L
I
A
R
L
D
Q
M
S
H
T
L
----
Q
G
I
W
E
G
A
S
S
E
A
F
I
-
Q
Q
Y
Q
E
L
R
P
S
F
E
K
M
A
V
L
L
N
E
V
G
Q
Q
L
H
N
S
--
A
T
I
-----
L
E
D
T
D
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
49.88
15%
-114
* C1 *
4I0X
-
?
A:
[3-77]
--------
D
E
V
G
A
L
S
K
F
A
A
S
L
A
D
Q
M
R
A
G
S
N
S
L
D
R
D
V
Q
S
L
F
----
G
V
W
K
G
S
A
A
D
A
Y
R
-
S
G
W
D
E
M
Q
D
G
A
T
K
V
W
N
A
L
T
D
I
A
S
T
L
G
S
N
--
A
A
A
-----
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
49.40
13%
-118
- C1 -
4I0X
2
?
B:
[8-90]
--
E
F
S
F
D
L
D
H
I
E
Q
V
T
S
R
A
R
G
F
K
E
F
V
T
E
N
L
D
Q
L
E
S
R
A
Q
K
L
V
Q
--
S
G
Q
W
A
G
A
A
A
A
A
Y
S
-
Q
A
H
K
E
W
M
D
A
A
R
E
L
V
E
G
L
S
Q
M
E
E
A
A
R
T
A
--
H
G
A
-----
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
49.13
14%
-95
- C1 -
4LWS
5
?
A:
[35-120]
--
Q
S
A
V
D
R
A
A
M
A
Q
A
A
Q
D
I
E
Q
S
A
N
A
I
R
G
M
Q
N
Q
L
A
S
A
K
D
Q
L
----
R
S
H
W
E
G
D
A
S
M
A
F
E
-
A
V
F
N
R
F
N
E
D
F
S
R
V
L
K
A
L
D
G
M
H
E
S
L
V
Q
T
--
R
I
T
-----
Y
E
A
R
E
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------