@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv0168: (2016-04-20 )
MSTAAVLRARFPRAVANLRQYGGAAARGLDEAGQLTWFALTSIGQIAHALRYYRKETLRLIAQIGMGTGAMAVVGGTVAIVGFVTLSGSSLVAIQGFASLGNIGVEAFTGFFAALINVRIAGPVVTGVALAATVGAGATAELGAMRISEEIDALEVMGIKSISFLASTRIMAGLVVIIPLYALAMIMSFLSPQITTTVLYGQSNGTYEHYFQTFLRPDDVFWSFLEALIITAIVMVSHCYYGYAAGGGPVGVGEAVGRSMRFSLVSVQVVVLFAALALYGVDPNFNLTV
Atome Classification :
(20 SA)
----------------------------..-.......10..---------......20........30.-.----.-.....40..---.----.....50........60....-------------....70.----------------....--...80.-------------...----------....90.--------.......100...----------....110........120..------------------..-...130.........140...-....150------.........160.......170.......---------180.......190.---......-200....----..-.210......-.220......----------.230.......----------240......---------.250.......260.......270......-----.280.......---------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------M
S
-
T
A
A
V
L
R
A
R
F
P
R
---------
A
V
A
N
L
R
Q
YG
G
A
A
ARGLDEA-G----
Q
-
L
T
W
F
A
L
T
S
I
---
G
----
Q
I
A
H
A
L
R
Y
Y
R
K
E
T
L
R
L
I
A
Q
IG-------------MGTG
A
M
A
----------------VVGG--
T
V
A
I
V
G
-------------
F
V
T
----------LSG
S
S
L
V
--------
A
I
QG
F
A
S
L
G
N
I
G
V
----------
E
A
F
T
G
-
F
F
A
A
L
I
N
V
R
IAG
P
V
------------------
V
T
-
G
V
A
L
--
A
A
TVGAGATAEL
G
A
M
-
R
I
S
E
E--------I
D
A
L
E
V
MGI
K
S
I
S
F
L
A
S
T
R
I
M
A
G
L
V
V
I
I
P
---------
L
Y
A
L
A
M
I
M
S
F
LSPQ---
I
T
T
T
V
L
-
Y
GQSNG
T
----
Y
E
-
H
Y
F
Q
T
FLRP
D
-
D
V
F
W
S
F
L
E
A
L
----------
I
I
T
A
I
V
M
V
S
H
C----------Y
Y
G
YAAGGG---------PV
G
V
G
E
A
VG
R
S
M
R
F
S
L
V
S
V
Q
V
V
V
L
F
A
A
L
A
L
-----YGVDPNFNLTV---------
27
Fugue
90.20
20%
-113
- C4 -
4MND
4
DIPPS_ARCFU
A:
[40-457]
L
M
K
A
V
I
L
A
A
G
LGGGVPKPLVRVGGCE
I
I
L
R
-
T
M
K
L
L
S
P
H
V
S
E
---------
F
I
I
V
A
S
R
Y
A
D
D
I
D
A
F
L
K
D
K
-
G
FN
Y
-
K
-
I
V
R
H
D
R
P
E
K
---
G
----
N
G
Y
S
L
L
V
A
K
N
H
V
E
D
R
F
I
L
T
M
G
D
H
V
Y
S
Q
Q
F
I
E
K
A
V
R
G
E
G
V
I
A
D
REPRFVDIGEAT
K
I
R
V
E
D
G
--
R
V
A
K
I
G
KDLREFDCVDTG
F
F
V
L
D
D
S
I
F
E
H
A
E
K
L
R
D
R
E
E
I
--------
P
L
S
E
I
V
K
L
A
R
L
P
V
----------
T
Y
V
D
G
-
E
L
W
M
D
V
D
T
K
E
D
V
R
R
------------------
A
N
-
R
A
L
V
--
S
A
A
V
G
D
G
F
I
S
R
K
I
N
R
-
K
I
S
T
R
--------
I
S
A
A
I
V
N
K
V
N
P
N
Q
M
T
L
I
S
F
L
V
G
A
F
S
A
L
A
S
FFS
I
P
L
A
G
L
L
Y
Q
F
S
S
I
L
D
G
C
D
G
E
---
I
A
R
A
S
L
K
M
S
K
K
G
G
Y
----
V
D
-
S
I
L
D
R
F
V
--
D
-
F
L
F
L
A
I
I
A
L
L
Y
PKT
A
T
V
A
M
F
A
I
F
G
S
V
M
V
S
Y
T
----------
S
E
K
Y
K
A
E
F
G
ESIRVLNYI
P
G
K
R
D
E
R
I
F
L
I
M
I
F
C
L
L
S
A
I
S
L
Q
W
I
F
W
M
F
L
-----
F
V
A
A
I
S
L
T
R
V
V
V
T
L
L
A
V
L
V
S
31
Fugue
67.05
18%
-92
- C2 -
4XB6
2
PHNI_ECOLI
C:
[1-353]
-----------------M
Y
V
A
V
K
G
G
E
K
A
I
D
-
A
A
H
A
L
Q
E
S
R
R
R
GDTDLPELS
V
A
Q
I
E
Q
Q
L
N
L
A
V
D
R
V
M
T
E
G
-
G
IAD
R
E
-
L
A
A
L
A
L
K
Q
A
---
S
GD
N
V
E
A
I
F
L
L
R
A
Y
R
T
T
L
A
K
L
A
V
S
E
P
-------------
L
D
T
T
G
M
R
----------------
L
E
R
R
--
I
S
A
V
---------------
Y
K
D
----------
I
P
G
G
Q
L
L
GPTYDYTH
R
L
L
D
F
T
L
L
A
N
G
E
A
P
T
L
T
T
A
D
SEQ
Q
P
S
P
H
-
V
F
S
L
L
A
R
Q
G
L
A
K
F
E
EDSG
A
Q
P
D
D
ITRTPPVYP
C
S
-
R
S
S
R
--
L
Q
Q
L
M
R
G
D
E
G
Y
L
L
A
L
-
A
Y
S
T
Q
R
GYGRNHP
F
A
G
E
I
R
S
G
Y
I
D
V
S
I
V
P
E
E
L
G
F
A
V
N
V
G
E
L
L
---------
M
T
E
C
E
M
V
N
G
F
I
D
P
P
GE
P
P
H
F
T
R
G
-
Y
G
L
V
F
G
M
----
S
E
-
R
K
A
M
A
M
A
L
V
D
-
R
A
L
Q
A
P
E
Y
G
E
----------
H
A
T
G
P
A
Q
D
E
E
F
----------
V
L
A
H
A
-----------------
D
N
V
E
V
A
G
F
V
S
H
L
K
L
P
H
Y
V
D
F
Q
A
E
L
E
L
-----
L
K
R
L
Q
Q
E
Q
N
H
----------
32
Fugue
65.75
13%
-70
- C3 -
1IXK
-
?
A:
[3-315]
--------------------------LS
P
S
M
L
D
K
L
L
R
L
G
Y
S
K
L
--------
F
A
D
R
Y
F
Q
L
W
G
E
R
A
I
R
I
A
E
A
M
E
----
K
-
P
L
P
R
C
F
R
V
------------
N
T
L
K
I
S
V
Q
D
L
V
K
R
L
N
K
K
G
-------------
F
Q
F
K
R
V
P
----------------
W
------
A
K
E
G
F
-------------
C
L
T
----------
R
E
P
F
S
I
T
--------
S
T
P
E
F
L
T
-
G
L
I
Y
I
----------
Q
E
A
S
S
M
Y
P
P
V
A
L
D
P
K
P
G
E
I
V
------------------
A
D
M
A
A
A
P
--
G
-----
G
K
T
S
Y
L
A
Q
L
M
R
N
D
G
V
--------
I
Y
A
F
D
V
-
D
E
N
R
L
R
E
T
R
L
N
L
S
R
L
G
V
L
N
V
I
L
---------
F
H
S
S
S
L
H
I
G
E
L
N
V
E
---
F
D
K
I
L
L
-
D
A
P
C
T
G
S
GTIH
R
T
M
D
D
I
K
F
C
Q
G
L
Q
M
R
L
L
E
K
G
L
E
V
L
----------
K
P
G
G
I
L
V
Y
S
T
C
SLEPEEN
E
F
V
I
Q
W
A
L
D
N
F
D
---------
V
E
L
L
P
L
K
Y
G
E
P
A
L
T
N
P
F
G
I
E
L
S
E
E
I
K
N
A
R
R
L
Y
PDV
H
E
T
S
G
F
F
I
A
K
I
R
K
L------
10
PsiBlast_CBE
55.53
33%
-48
- C4 -
4ZBA
3
?
C:
[120-175]
-----------------------------------------------------------------------
G
----
Q
-
L
V
W
F
T
L
Y
H
E
---
E
----
K
I
P
S
A
V
T
R
Y
K
E
E
A
L
R
V
F
S
V
L
E
R------------
V
L
S
N
Q
E
W
----------------
L
V
G
G
KM
T
I
A
D
I
S
-------------
F
V
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
55.43
32%
-54
- C4 -
4ZBB
6
?
A:
[120-178]
-----------------------------------------------------------------------
G
----
Q
-
L
V
W
F
T
L
Y
H
E
---
E
----
K
I
P
S
A
V
T
R
Y
K
E
E
A
L
R
V
F
S
V
L
E
R
------------
V
L
S
N
Q
E
W
----------------
L
V
G
G
KM
T
I
A
D
I
S
-------------
F
V
S
----------
W
N
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
55.40
17%
-14
- C4 -
2A3D
-
?
A:
[1-73]
----------------------------
M
G
-
S
W
A
E
F
K
Q
R
L
A
A
---------
I
K
T
R
L
Q
A
L
G
G
S
E
A
E
L
A
A
F
E
-
K
----
E
-
I
A
A
F
E
S
E
L
Q
AYK
G
----
K
G
N
P
E
V
E
A
L
R
K
E
A
A
A
I
R
D
E
L
Q
-------------
A
Y
R
H
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
54.92
32%
-49
- C4 -
4ZBA
3
?
A:
[120-178]
-----------------------------------------------------------------------
G
----
Q
-
L
V
W
F
T
L
Y
H
E
---
E
----
K
I
P
S
A
V
T
R
Y
K
E
E
A
L
R
V
F
S
V
L
E
R
------------
V
L
S
N
Q
E
W
----------------
L
V
G
G
KM
T
I
A
D
I
S
-------------
F
V
S
----------
W
N
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_CBE
54.82
33%
-50
- C4 -
4ZBA
3
?
D:
[120-175]
-----------------------------------------------------------------------
G
----
Q
-
L
V
W
F
T
L
Y
H
E
---
E
----
K
I
P
S
A
V
T
R
Y
K
E
E
A
L
R
V
F
S
V
L
E
R------------
V
L
S
N
Q
E
W
----------------
L
V
G
G
KM
T
I
A
D
I
S
-------------
F
V
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_CBE
54.75
33%
-48
- C4 -
4ZBB
5
?
B:
[120-175]
-----------------------------------------------------------------------
G
----
Q
-
L
V
W
F
T
L
Y
H
E
---
E
----
K
I
P
S
A
V
T
R
Y
K
E
E
A
L
R
V
F
S
V
L
E
R------------
V
L
S
N
Q
E
W
----------------
L
V
G
G
KM
T
I
A
D
I
S
-------------
F
V
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_CBE
54.37
33%
-49
- C4 -
4ZBA
3
?
B:
[120-175]
-----------------------------------------------------------------------
G
----
Q
-
L
V
W
F
T
L
Y
H
E
---
E
----
K
I
P
S
A
V
T
R
Y
K
E
E
A
L
R
V
F
S
V
L
E
R
------------
V
L
S
N
Q
E
W
----------------
L
V
G
G
KM
T
I
A
D
I
S
-------------
F
V
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_CBE
54.33
33%
-48
- C4 -
4ZBB
6
?
D:
[120-175]
-----------------------------------------------------------------------
G
----
Q
-
L
V
W
F
T
L
Y
H
E
---
E
----
K
I
P
S
A
V
T
R
Y
K
E
E
A
L
R
V
F
S
V
L
E
R------------
V
L
S
N
Q
E
W
----------------
L
V
G
G
KM
T
I
A
D
I
S
-------------
F
V
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_CBE
53.60
33%
-51
- C4 -
4ZB9
1
?
D:
[120-175]
-----------------------------------------------------------------------
G
----
Q
-
L
V
W
F
T
L
Y
H
E
---
E
----
K
I
P
S
A
V
T
R
Y
K
E
E
A
L
R
V
F
S
V
L
E
R------------
V
L
S
N
Q
E
W
----------------
L
V
G
G
KM
T
I
A
D
I
S
-------------
F
V
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_CBE
53.44
33%
-49
- C4 -
4ZBB
7
?
C:
[120-175]
-----------------------------------------------------------------------
G
----
Q
-
L
V
W
F
T
L
Y
H
E
---
E
----
K
I
P
S
A
V
T
R
Y
K
E
E
A
L
R
V
F
S
V
L
E
R------------
V
L
S
N
Q
E
W
----------------
L
V
G
G
KM
T
I
A
D
I
S
-------------
F
V
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_CBE
53.39
33%
-53
- C4 -
4ZB9
1
?
C:
[120-175]
-----------------------------------------------------------------------
G
----
Q
-
L
V
W
F
T
L
Y
H
E
---
E
----
K
I
P
S
A
V
T
R
Y
K
E
E
A
L
R
V
F
S
V
L
E
R------------
V
L
S
N
Q
E
W
----------------
L
V
G
G
KM
T
I
A
D
I
S
-------------
F
V
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_CBE
53.02
33%
-54
- C4 -
4ZB9
1
?
B:
[120-175]
-----------------------------------------------------------------------
G
----
Q
-
L
V
W
F
T
L
Y
H
E
---
E
----
K
I
P
S
A
V
T
R
Y
K
E
E
A
L
R
V
F
S
V
L
E
R------------
V
L
S
N
Q
E
W
----------------
L
V
G
G
KM
T
I
A
D
I
S
-------------
F
V
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
52.94
32%
-56
- C4 -
4ZB9
1
?
A:
[120-178]
-----------------------------------------------------------------------
G
----
Q
-
L
V
W
F
T
L
Y
H
E
---
E
----
K
I
P
S
A
V
T
R
Y
K
E
E
A
L
R
V
F
S
V
L
E
R
------------
V
L
S
N
Q
E
W
----------------
L
V
G
G
KM
T
I
A
D
I
S
-------------
F
V
S
----------
W
N
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
45.44
21%
-35
- C4 -
1PGY
-
A:
[1-47]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
V
D
E
V
K
---------
D
M
E
I
A
R
L
M
S
L
-
G
L
S
---
I
E
E
A
T
E
-
F
Y
E
N
D
V
T
----
Y
E
-
R
Y
L
E
I
L
K
S
K
Q
-
K
E
----------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
45.11
44%
-9
- C4 -
3J09
-
COPA_ARCFU
A:
[368-414]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
F
T
T
-
L
I
A
V
L
V
---
V
A
C
P
C
------------------
A
F
-
G
L
A
T
P
T
A
L
T
V
G
M
G
K
G
A
E
L
G
I
L
---
I
K
N
--------
A
D
A
L
E
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
42.91
14%
85
* C4 *
1G1J
1
NSP4_ROTS1
A:
[1-43]
-------------------------------------------------------
I
E
K
Q
M
D
R
V
V
K
E
M
R
R
Q
-
L
----
E
M
I
D
K
L
T
T
R
E
I
---
E
----
Q
V
E
L
L
K
R
I
Y
D
K
L
T
V
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
42.09
10%
-11
- C4 -
4GKW
-
SAS6_CAEEL
A:
[250-407]
-----------------------------
E
-
D
K
E
D
E
V
A
D
L
K
Q
---------
D
T
E
S
L
Q
K
Q
L
E
E
N
Q
E
E
L
E
I
V
-
G
----
N
-
M
L
R
E
E
Q
G
K
V
---
D
----
Q
L
Q
K
R
N
V
A
H
Q
K
E
I
G
K
L
R
A
E
L
G
-------------
T
A
Q
R
N
L
E
----------------
K
A
D
Q
--
L
L
K
R
N
S
-------------
Q
Q
Q
----------
N
Q
Q
S
L
D
M
--------
R
K
L
G
E
L
E
A
D
L
K
E
K
----------
D
S
M
V
E
-
S
L
T
E
T
I
G
I
L
R
K
E
L
E
------------------
N
E
-
K
L
K
A
--
A
E
N
M
D
S
F
E
K
L
S
M
E
N
E
-
N
L
K
E
K
--------
I
A
H
Y
R
A
Q
R
F
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------