@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv0171: (2016-04-20 )
MRTLEPPNRMRIGLMGIVVALLVVAVGQSFTSVPMLFAKPSYYGQFTDSGGLHKGDRVRIAGLGVGTVEGLKIDGDHIVVKFSIGTNTIGTESRLAIRTDTILGRKVLEIEPRGAQALPPGGVLPVGQSTTPYQIYDAFFDVTKAASGWDIETVKRSLNVLSETVDQTYPHLSAALDGVAKFSDTIGKRDEQITHLLAQANQVASILGDRSEQVDRLLVNAKTLIAAFNERGRAVDALLGNISAFSAQVQNLINDNPNLNHVLEQLRILTDLLVDRKEDLAETLTILGRFSASFGETFASGPYFKVLLANLVPGQILQPFVDAAFKKRGISPEDFWRSAGLPAYRWPDPNGTRFPNGAPPPPPPVLEGTPEHPGPAVPPGSPCSYTPPADGLPRPWDPLPCANLTQGPFGGPDFPAPLDVATSPPNPDGPPPAPGLPIAGRPGEVPPNVPGTPVPIPQEAPPGARTLPLGPAPGPAPPPAAPGPPAPPGPGPQLPAPFINPGGTGGSGVTGGSEN
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70...---.....80......----..90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......-----200--..-......--.210.......220.......230.----...--...240---------.......250.......260...---....270.......280.......290.......300.......310.......320.......330.......340.......350...-..----..360...-....370....---...380--.......390.......400.......410.......420.......430...-....440.......450.......460.......470.......480.......490.......--------.500.......510.....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MRTLEPPN
R
M
R
I
G
L
M
G
I
V
V
A
L
L
V
V
A
VG
Q
S
FTSV
P
M
L
F
AKPSY
Y
G
QFTDSGGLHKG
D
R
V
R
I
A
G
L
GVG
T
V
E
G
L
K
ID---G
D
H
I
V
V
K
F
SIGTN----TIGTE
S
R
L
A
I
R
TDTILG
R
K
V
L
E
IEPRGAQALPPG
G
V
LPVGQSTT
P
Y
Q
I
Y
D
A
F
F
D
V
T
KAASGW
D
I
E
T
V
K
R
S
L
N
V
L
S
E
T
V
D
QTY
P
H
L
S
A
A
L
D
G
V
A
K
F
S
D
TIGK
R
D
E
Q
I
T
H
L
L
A
Q
-----
A
----
N
Q
-
V
A
S
I
LG--D
R
S
E
Q
V
D
R
L
L
V
N
A
K
T
L
I
A
A
F
N
ERG
R
----
A
V
D
--
A
L
L
G
N
I
---------
S
A
F
S
A
Q
V
Q
N
L
INDNP
N
L
N
H
V
L
E
Q
---
L
R
I
L
T
D
L
L
VD
R
K
E
D
L
A
E
T
L
T
I
L
G
R
F
S
A
S
FGETFASG
P
Y
F
K
V
L
L
A
NLV
P
G
Q
I
L
Q
P
F
V
D
A
A
F
K
KRGI
S
P
E
D
F
W
R
SAGLPAYRWPDPNGTRFP-NG----APPPPPPV-LEGTPEHPGPA---VPPGSP--CSYTPPADGLPRPWDPLPCANLTQGPFGGPDFPAPLDVATSPPNPDGPPPAPG-LPIAGRPGEVPPNVPGTPVPIPQEAPPGARTLPLGPAPGPAPPPAAPGPPAPPGPG-PQLPAPF--------INPGGTGGSGVT--GGSEN
22
Fugue
88.25
16%
-46
- C8 -
4E40
-
?
A:
[3-247]
-------------------------------------------
G
E
I
K
V
E
--
L
E
D
S
D
D
V
A
A
A
C
E
L
R
A
Q
L
A
G
V
S
I
A
---
S
G
I
L
L
R
P
A
V
I
R
N
A
----
T
T
E
F
S
R
K
K
S
E
D
I
L
A
K
G
G
A
A
V
E
R
A
S
A
A
V
D
R
------
V
S
G
L
D
K
T
N
E
T
A
Q
K
V
R
K
A
A
A
V
A
H
H
A
----
L
E
H
V
K
E
E
V
E
I
V
A
K
K
V
N
E
I
I
E
L
T
A
G
A
T
E
H
A
K
G
A
K
A
N
G
D
A
S
A
V
K
V
S
N
L
L
A
R
-----
A
K
E
SE
N
Q
-
Y
V
K
E
A
A
--
E
E
C
S
E
S
T
N
Y
D
V
T
A
K
S
L
A
A
A
L
D
K
L
P
G
----
V
K
E
DN
A
V
K
T
T
F
---------
Q
S
I
L
T
S
L
D
N
L
D
K
D
V
K
S
V
E
Q
R
A
E
E
---
L
E
T
A
L
E
K
A
E
R
Q
L
E
K
A
E
K
A
A
E
E
A
E
T
E
S
S
K
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
65.41
33%
-39
- C3 -
3WMM
-
?
H:
[62-167]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
D
P
K
T
F
V
L
P
H
N
G
GTVV
A
P
R
V
E
A
P
V
A
V
N
A
T
P
F
S
P
A
P
G
SPL
V
P
N
G
D
P
ML
S
G
F
G
P
A
A
S
----
P
D
R
P
K
H
C
-
D
L
T
---
F
E
G
L
P
K
I
V
P
M
R
V
A
K
E
F
S
I
A
E
G
D
P
D
P
R
G
-
M
T
V
V
G
L
D
G
E
V
A
G
T
V
-----------------------------------------------------------------------------
4
PsiBlast_PDB
65.39
23%
-40
- C8 -
2CH7
-
MCP2_THEMA
B:
[179-308]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
E
N
V
R
R
V
V
N
E
I
R
S
I
A
E
D
A
G
K
V
S
S
E
I
T
A
R
V
E
E
G
T
K
L
A
D
E
-----
A
----
D
E
K
L
N
S
I
V
G
---
A
V
E
R
I
N
E
M
L
Q
N
---
I
A
A
A
I
E
E
Q
N
A
----
A
V
D
--
E
I
T
T
A
M
---------
T
E
N
A
K
N
A
E
E
I
T
N
S
V
K
E
V
N
A
R
L
Q
E
---
I
S
A
S
T
E
E
V
T
S
R
V
Q
T
I
R
E
N
V
Q
M
L
K
E
I
V
A
R
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
63.96
23%
-38
- C8 -
3JA6
-
MCP2_THEMA
G:
[399-528]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
E
N
V
R
R
V
V
N
E
I
R
S
I
A
E
D
A
G
K
V
S
S
E
I
T
A
R
V
E
E
G
T
K
L
A
D
E
-----
A
----
D
E
K
L
N
S
I
V
G
---
A
V
E
R
I
N
E
M
L
Q
N
---
I
A
A
A
I
E
E
Q
T
A
----
A
V
D
--
E
I
T
T
A
M
---------
T
E
N
A
K
N
A
E
E
I
T
N
S
V
K
E
V
N
A
R
L
Q
E
---
I
S
A
S
T
E
E
V
T
S
R
V
Q
T
I
R
E
N
V
Q
M
L
K
E
I
V
A
R
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
61.64
13%
-72
- C8 -
3T6G
-
BCAR1_HUMAN
B:
[96-229]
---------------------------------------------------------------------------------------------------------------------------------------------------------------
S
D
R
Q
L
L
L
F
Y
L
E
Q
C
E
A
N
L
T
T
L
T
N
A
V
D
A
F
F
T
A
V
A
T
-
N
Q
P
P
K
I
F
V
A
H
S
K
F
-----
V
----
I
L
-
S
A
H
K
L
V
--
F
I
G
D
T
L
S
R
Q
-
A
K
A
A
D
V
R
S
Q
V
T
H
Y
S
N
----
L
L
C
--
D
L
L
R
G
I
---------
V
A
T
T
K
A
A
A
L
Q
Y
P
S
P
S
A
A
Q
D
M
V
E
R
---
V
K
E
L
G
H
S
T
Q
Q
F
R
R
V
L
G
Q
L
A
A
A
L
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
60.88
16%
-77
- C8 -
1WRD
-
TOM1_HUMAN
A:
[210-307]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
P
L
G
S
E
Q
I
G
K
L
R
S
E
L
E
M
V
S
G
N
-----
V
----
R
V
-
M
S
E
M
L
T
E
L
V
P
T
Q
A
E
P
A
D
L
E
L
L
Q
E
L
N
R
T
C
R
A
M
Q
Q
----
R
V
L
--
E
L
I
P
Q
I
---------
A
N
-
E
Q
L
T
E
E
L
L
I
V
N
D
N
L
N
N
V
F
L
R
---
H
E
R
F
E
R
F
R
T
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
58.55
14%
-3
- C8 -
2QIH
10
?
A:
[17-152]
---------------------------------------------------------------------------------------------------------------------------------------------------------
N
T
D
R
I
A
T
A
E
L
G
I
A
E
N
K
K
D
A
Q
I
A
K
A
Q
A
N
E
N
K
D
G
I
A
K
N
Q
A
D
I
Q
L
H
D
K
K
I
T
N
L
G
I
L
-----
H
----
S
M
-
V
A
R
A
V
G
--
N
N
T
Q
G
V
A
T
N
K
A
D
I
A
K
N
Q
A
D
I
A
N
N
I
K
----
N
I
Y
--
E
L
A
Q
Q
Q
---------
D
Q
H
S
S
D
I
K
T
L
A
K
V
S
A
A
N
T
D
R
I
A
K
---
N
K
A
E
A
D
A
S
F
E
T
L
T
K
N
Q
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
58.42
36%
-5
- C6 -
2ADZ
-
SNTA1_MOUSE
A:
[49-113]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
P
E
P
E
P
A
Q
L
N
G
A
A
E
P
G
A
A
P
P
Q
L
P
-
E
A
L
L
L
Q
R
E
V
S
P
Y
F
K
N
S
A
G
G
T
S
V
G
W
D
S
P
P
A
S
P
L
Q
R
Q
P
S
S
P
G
-
P
Q
--------------------------------
25
Fugue
57.21
19%
0
- C8 -
2JEE
-
ZAPB_ECOLI
A:
[3-80]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
S
L
E
V
F
E
K
L
E
A
K
V
Q
Q
A
I
D
T
I
T
L
L
Q
M
E
I
E
E
L
K
E
K
-----
N
----
N
S
-
L
S
Q
E
V
Q
--
N
A
Q
H
Q
R
E
E
L
E
R
E
N
N
H
L
K
E
Q
Q
N
G
W
Q
E
----
R
L
Q
--
A
L
L
G
R
M
---------
E
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
57.20
35%
-28
- C5 -
1Z87
-
SNTA1_MOUSE
A:
[44-102]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
A
D
G
E
P
G
P
E
P
E
P
A
Q
L
N
G
A
A
E
P
G
A
A
P
P
Q
L
P
E
A
L
LL
Q
R
R
R
V
T
V
R
K
A
D
A
G
G
L
G
I
S
I
K
G
G
R
E
N
26
Fugue
56.17
10%
-30
- C8 -
5CWS
1
NSP1_CHATD
C:
[1-183]
----------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
E
I
I
T
R
W
A
T
D
L
A
K
Y
Q
K
E
F
K
E
Q
A
A
K
V
M
E
W
D
R
L
L
V
E
N
G
E
K
I
Q
K
L
Y
T
S
-----
T
----
Y
E
-
A
E
R
A
S
N
--
E
I
E
R
Q
L
S
N
V
E
S
Q
Q
E
E
L
T
A
W
L
D
R
Y
E
R
----
E
L
D
--
E
L
Y
A
K
Q
M
GE
R
T
Y
K
L
A
E
K
L
T
D
Q
L
D
E
M
G
K
D
L
A
K
M
I
K
E
I
N
D
---
M
S
N
T
L
S
K
G
S
K
P
D
D
P
L
T
Q
I
V
R
V
L
N
G
H
L
A
Q
L
Q
W
I
D
T
N
A
A
A
L
Q
A
K
V
A
A
A
Q
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
55.95
28%
15
- C7 -
3H2K
2
?
A:
[311-397]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
Q
D
L
A
R
N
N
L
L
E
W
-----
A
----
P
Q
-
T
P
T
L
L
C
--
G
S
S
N
D
A
T
V
P
L
K
N
A
Q
T
A
I
A
S
F
Q
Q
R
G
S
NQ
V
A
L
V
D
--
T
G
T
G
N
A
---------
S
-----------
D
N
S
A
F
A
H
M
L
T
K
E
S
C
I
V
V
V
R
D
Q
L
L
D
K
Q
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
55.89
28%
20
- C7 -
3H2G
-
?
A:
[311-397]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
Q
D
L
A
R
N
N
L
L
E
W
-----
A
----
P
Q
-
T
P
T
L
L
C
--
G
S
S
N
D
A
T
V
P
L
K
N
A
Q
T
A
I
A
S
F
Q
Q
R
G
S
NQ
V
A
L
V
D
--
T
G
T
G
N
A
---------
S
-----------
D
N
S
A
F
A
H
M
L
T
K
E
S
C
I
V
V
V
R
D
Q
L
L
D
K
Q
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
55.54
28%
14
- C7 -
3H2I
-
?
A:
[311-397]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
Q
D
L
A
R
N
N
L
L
E
W
-----
A
----
P
Q
-
T
P
T
L
L
C
--
G
S
S
N
D
A
T
V
P
L
K
N
A
Q
T
A
I
A
S
F
Q
Q
R
G
S
NQ
V
A
L
V
D
--
T
G
T
G
N
A
---------
S
-----------
D
N
S
A
F
A
H
M
L
T
K
E
S
C
I
V
V
V
R
D
Q
L
L
D
K
Q
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
55.43
28%
15
- C7 -
3H2J
-
?
A:
[311-397]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
Q
D
L
A
R
N
N
L
L
E
W
-----
A
----
P
Q
-
T
P
T
L
L
C
--
G
S
S
N
D
A
T
V
P
L
K
N
A
Q
T
A
I
A
S
F
Q
Q
R
G
S
NQ
V
A
L
V
D
--
T
G
T
G
N
A
---------
S
-----------
D
N
S
A
F
A
H
M
L
T
K
E
S
C
I
V
V
V
R
D
Q
L
L
D
K
Q
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
55.23
26%
10
- C7 -
4F1J
10
?
A:
[43-131]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
N
A
I
H
L
Y
A
N
I
F
S
N
N
A
----
K
E
-
I
I
R
L
H
S
--
D
A
S
K
N
K
E
K
A
L
I
I
I
K
S
L
L
S
T
N
L
P
Y
G
R
----
T
--------
N
L
---------
S
D
A
L
L
Q
V
R
K
H
L
N
D
R
I
N
R
E
N
A
N
Q
L
---
V
V
I
L
T
D
G
I
P
D
S
I
Q
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
55.15
28%
16
- C7 -
3H2H
-
?
A:
[311-397]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
Q
D
L
A
R
N
N
L
L
E
W
-----
A
----
P
Q
-
T
P
T
L
L
C
--
G
S
S
N
D
A
T
V
P
L
K
N
A
Q
T
A
I
A
S
F
Q
Q
R
G
S
NQ
V
A
L
V
D
--
T
G
T
G
N
A
---------
S
-----------
D
N
S
A
F
A
H
M
L
T
K
E
S
C
I
V
V
V
R
D
Q
L
L
D
K
Q
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
55.13
26%
3
* C7 *
4F1K
7
?
A:
[43-131]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
N
A
I
H
L
Y
A
N
I
F
S
N
N
A
----
K
E
-
I
I
R
L
H
S
--
D
A
S
K
N
K
E
K
A
L
I
I
I
K
S
L
L
S
T
N
L
P
Y
G
R
----
T
--------
N
L
---------
S
D
A
L
L
Q
V
R
K
H
L
N
D
R
I
N
R
E
N
A
N
Q
L
---
V
V
I
L
T
D
G
I
P
D
S
I
Q
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
50.89
21%
12
- C8 -
5C9N
2
GEMC1_HUMAN
A:
[6-69]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
P
D
L
C
S
W
E
E
A
Q
L
S
S
Q
L
Y
R
N
K
Q
L
Q
D
T
L
V
Q
K
E
E
E
L
A
R
L
H
E
E
-----
N
----
N
H
-
L
R
Q
Y
L
----
N
S
A
L
V
K
C
E
E
E
K
A
K
K
E
L
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
46.72
25%
-26
- C4 -
1MOE
-
KV3A8_MOUSE
A:
[58-157]
---------------------------------------------------
L
E
S
G
I
P
V
R
F
S
G
T
G
S
R
T
D
F
T
L
I
I
D
PVE
A
D
D
V
A
T
Y
Y
C
Q
Q
T
N
EDPY
T
F
G
G
G
T
K
L
E
I
K
G
G
G
S
G
G
G
G
E
V
Q
L
Q
Q
S
G
A
E
L
V
E
P
G
A
S
V
K
L
S
C
T
A
S
G
F
N
I
K
D
T
Y
M
H
W
V
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------