@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv0190: (2016-04-20 )
MTAAHGYTQQKDNYAKRLRRVEGQVRGIARMIEEDKYCIDVLTQISAVTSALRSVALNLLDEHLSHCVTRAVAEGGPGADGKLAEASAAIARLVRS
Atome Classification :
(20 SA)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10..-...------...20----------....---.....30.-----....-....40.......----.50......-.-----.----------------60......-------..70....-..--..80........90.....--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTAAHGYTQQ
K
D
N
-
Y
A
K
------
R
L
R
R
-----------
V
E
G
Q
---
V
R
G
I
A
R
-
M
-----
I
EED-
K
Y
C
I
D
V
L
T
Q
I
S
A
V
----
T
S
A
L
R
S
V
A
L
-
N
-----
L
----------------
L
D
E
H
L
S
H
C
-------
V
T
R
A
V
AEG-GP--GADG
K
L
A
E
A
S
A
A
I
A
R
L
VRS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_CBE
88.18
58%
-95
- C7 -
4ADZ
1
?
B:
[47-136]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
H
K
Q
K
A
E
-
H
L
K
------
R
L
R
R
-----------
I
E
G
Q
---
I
R
G
L
Q
R
-
M
-----
V
D
E
D
-
V
Y
C
I
D
I
L
T
Q
V
S
A
S
----
T
K
A
L
Q
S
F
A
L
-
Q
-----
L
----------------
L
E
E
H
L
R
H
C
-------
V
A
D
A
A
L
K
G
-
G
T
--
E
I
D
A
K
V
E
E
A
T
K
A
I
G
R
L
L
R
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
86.56
58%
-88
- C7 -
4UIG
2
?
A:
[45-135]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
G
Y
H
K
Q
K
A
E
-
H
L
K
------
R
L
R
R
-----------
I
E
G
Q
---
I
R
G
L
Q
R
-
M
-----
V
D
E
D
-
V
Y
C
I
D
I
L
T
Q
V
S
A
S
----
T
K
A
L
Q
S
F
A
L
-
Q
-----
L
----------------
L
E
E
H
L
R
H
C
-------
V
A
D
A
A
L
K
G
-
G
T
--
E
I
D
A
K
V
E
E
A
T
K
A
I
G
R
L
L
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
84.76
58%
-84
- C7 -
4ADZ
5
?
A:
[47-136]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
H
K
Q
K
A
E
-
H
L
K
------
R
L
R
R
-----------
I
E
G
Q
---
I
R
G
L
Q
R
-
M
-----
V
D
E
D
-
V
Y
C
I
D
I
L
T
Q
V
S
A
S
----
T
K
A
L
Q
S
F
A
L
-
Q
-----
L
----------------
L
E
E
H
L
R
H
C
-------
V
A
D
A
A
L
K
G
-
G
T
--
E
I
D
A
K
V
E
E
A
T
K
A
I
G
R
L
L
R
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
84.41
57%
-84
- C7 -
4ADZ
5
?
A:
[47-136]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
H
K
Q
K
A
E
-
H
L
K
------
R
L
R
R
-----------
I
E
G
Q
---
I
R
G
L
Q
R
-
M
-----
V
D
E
D
-
V
Y
C
I
D
I
L
T
Q
V
S
A
S
----
T
K
A
L
Q
S
F
A
L
-
Q
-----
L
----------------
L
E
E
H
L
R
H
C
-------
V
A
D
A
A
L
K
G
-
G
T
--
E
I
D
A
K
V
E
E
A
T
K
A
I
G
R
L
L
R
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
81.44
42%
-78
- C7 -
4M1P
3
?
A:
[14-104]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
P
R
T
K
E
E
I
E
N
-
I
M
K
------
R
L
K
R
-----------
I
E
G
Q
---
V
R
G
V
Q
K
-
M
-----
V
E
D
N
-
R
Y
C
I
D
I
L
V
Q
I
S
A
I
----
Q
A
A
L
R
Q
V
G
M
-
Q
-----
L
----------------
L
E
R
H
A
N
H
C
-------
V
A
K
A
I
R
E
G
-
S
----
G
E
Q
S
L
R
E
L
M
D
V
I
K
Q
F
A
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
66.31
54%
-107
- C7 -
4M1P
2
?
A:
[23-86]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
N
-
I
M
K
------
R
L
K
R
-----------
I
E
G
Q
---
V
R
G
V
Q
K
-
M
-----
V
E
D
N
-
R
Y
C
I
D
I
L
V
Q
I
S
A
I
----
Q
A
A
L
R
Q
V
G
M
-
Q
-----
L
----------------
L
E
R
H
A
N
H
C
-------
V
A
K
A
I
R
E
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
65.82
38%
-57
- C7 -
2HH7
1
CSOR_MYCTU
A:
[5-88]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
A
K
K
R
A
-
A
L
N
------
R
L
K
T
-----------
V
R
G
H
---
L
D
G
I
V
R
-
M
-----
L
E
S
D
-
A
Y
C
V
D
V
M
K
Q
I
S
A
V
----
Q
S
S
L
E
R
A
N
R
-
V
-----
M
----------------
L
H
N
H
L
E
T
C
-------
F
S
T
A
V
L
D
G
-
H
----
G
Q
A
A
I
E
E
L
I
D
A
V
K
F
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
65.80
36%
-69
- C7 -
2HH7
1
CSOR_MYCTU
A:
[4-88]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
T
A
K
K
R
A
-
A
L
N
------
R
L
K
T
-----------
V
R
G
H
---
L
D
G
I
V
R
-
M
-----
L
E
S
D
-
A
Y
C
V
D
V
M
K
Q
I
S
A
V
----
Q
S
S
L
E
R
A
N
R
-
V
-----
M
----------------
L
H
N
H
L
E
T
C
-------
F
S
T
-------
A
--
V
L
D
G
H
G
Q
A
A
I
E
E
L
I
D
A
V
K
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
62.62
44%
-66
- C7 -
2HH7
1
CSOR_MYCTU
A:
[6-73]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
A
K
K
R
A
-
A
L
N
------
R
L
K
T
-----------
V
R
G
H
---
L
D
G
I
V
R
-
M
-----
L
E
S
D
-
A
Y
C
V
D
V
M
K
Q
I
S
A
V
----
Q
S
S
L
E
R
A
N
R
-
V
-----
M
----------------
L
H
N
H
L
E
T
C
-------
F
S
T
A
V
L
D
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
56.00
20%
-80
- C7 -
2A3D
-
?
A:
[1-73]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
G
S
W
A
E
F
K
Q
R
L
A
A
-
I
K
T
------
R
L
Q
A
-----------
L
G
G
S
---
E
A
E
L
A
A
-
F
-----
E
K
E
I
-
A
A
F
E
S
E
L
Q
A
Y
K
G
-----------------------------------------------------------
K
G
-
N
P
--
E
V
E
-
A
L
R
K
E
A
A
A
I
R
D
E
L
Q
A
Y
R
HN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
55.57
12%
-85
- C7 -
2P61
-
?
A:
[34-153]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
F
D
I
L
E
D
V
K
E
D
H
-
F
E
K
------
L
L
E
E
-----------
A
V
E
E
---
V
I
D
S
G
N
-
E
-----
L
V
R
S
-
P
T
P
S
N
L
K
R
Y
K
N
A
I
----
K
E
F
L
K
L
I
E
K
-
K
-----
I
Y
K
LN
S
G
R
A
R
L
H
L
V
V
E
E
V
N
E
K
L
M
D
L
-------
T
E
K
I
M
K
N
E
-
W
Q
TI
N
L
A
A
R
I
E
E
I
N
G
L
I
L
N
L
Y
R
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
55.09
21%
-38
- C3 -
5I62
-
?
A:
[1-534]
GQVA
P
N
V
W
S
K
Y
F
NIPN
P
G
L
R
A
Y
F
S
N
V
V
S
GQP
E
V
Y
R
T
PFYKGMS
L
E
S
I
C
D
E
W
Y
K
K
L
V
SIDTQW
P
T
L
M
E
F
E
D
D
L
R
K
K
VGPMS
V
M
L
P
LKER
M
S
D
I
D
S
Y
Y
D
SIS
K
D
Q
V
P
F
D
T
K
A
I
S
A
A
K
S
E
W
KGVSRLRLRS
E
V
N
T
V
A
V
MKKSTNSGSPYFSKRKAVVSKTIP
C
D
V
Y
M
DGR
Y
C
V
M
R
Q
NG
R
E
W
S
G
A
A
V
L
G
W
R
G
Q
E
GGPKPTD
V
K
Q
R
V
V
WMFP
F
A
V
N
I
R
E
L
Q
V
Y
Q
P
L
I
L
T
F
Q
R
L
GLVPAWVS
M
E
A
V
D
R
R
I
T
K
M
F
D
T
KGPR
D
V
V
V
C
T
D
F
S
KFDQHFN
P
T
C
Q
S
V
A
K
E
L
L
A
D
L
L
TG
Q
E
A
V
D
W
L
E
R
VFPIKY
A
I
P
L
AYNWG
E
I
R
Y
G
I
HGMGSGSGG
T
N
A
D
E
T
L
V
H
R
V
L
Q
H
E
A
A
I
S
H
HTTLNPN
S
Q
C
L
GD
D
G
V
L
T
Y
PGIS
A
E
D
V
M
Q
S
Y
S
R
H
G
L
D
M
N
L
E
K
Q
Y
V
S
K
Q
D
C
T
Y
L
R
------
R
W
H
H
TDYRVDGMC
V
G
V
Y
S
T
---
M
R
A
L
G
R
-
L
-----
A
M
Q
E
-
R
Y
Y
D
P
D
V
W
G
E
K
M
V
----
T
L
R
Y
L
S
I
I
E
-
N
V
K
YHP
L
----------------
K
E
E
F
L
D
F
C
-------
I
K
G
D
K
T
R
L
-
G
L
--
G
I
P
G
F
L
D
N
I
A
G
E
A
Q
K
G
I
E
N
W
W
V
V
Q
A
L
K
S
R
R---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
52.01
32%
2
- C7 -
3AAI
-
?
A:
[7-92]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
L
D
P
K
V
R
E
E
-
A
R
R
------
R
L
L
S
-----------
A
K
G
H
---
L
E
G
I
L
R
-
M
-----
L
E
D
E
K
V
Y
C
V
D
V
L
K
Q
L
K
A
V
----
E
G
A
L
D
R
V
G
E
-
M
-----
V
----------------
L
R
A
H
L
K
D
H
----------------
D
----
V
E
E
I
V
E
E
L
M
E
A
L
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
50.15
2%
-67
* C7 *
3EVY
-
?
A:
[662-744]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
P
Y
E
K
L
V
E
R
-
F
N
E
------
M
A
A
E
-----------
F
L
S
Y
---
F
P
T
V
K
S
-
V
G
N
LES
E
L
D
K
-
R
R
F
V
I
L
F
R
A
M
L
R
L
----
R
N
E
V
K
G
Y
N
E
-
F
-----
D
----------------
A
E
D
L
---------------------
T
--
I
E
E
Q
R
F
A
D
Y
Q
S
K
Y
L
D
M
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
49.82
32%
-5
- C7 -
3AAI
-
?
A:
[7-92]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
L
D
P
K
V
R
E
E
-
A
R
R
------
R
L
L
S
-----------
A
K
G
H
---
L
E
G
I
L
R
M
L
-----
E
D
E
K
-
V
Y
C
V
D
V
L
K
Q
L
K
A
V
----
E
G
A
L
D
R
V
G
E
M
V
-----
L
----------------
R
A
H
L
K
D
H
D
-------
V
E
E
I
V
E
E
L
M
E
A
--
L
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
46.99
20%
-41
- C7 -
1XOU
-
?
B:
[2-85]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
I
V
S
Q
T
R
N
K
E
L
-
L
D
K
------
K
I
R
S
-----------
E
I
E
A
---
I
K
K
I
I
A
-
E
-----
F
D
V
V
-
K
E
S
V
N
E
L
S
E
-
K
A
K
----
T
D
P
Q
A
A
E
K
L
-
N
-----
K
----------------
L
I
E
G
Y
T
Y
G
-------
E
E
R
K
L
Y
D
S
-
A
L
--
S
K
I
E
K
L
I
E
T
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
45.88
17%
-102
- C7 -
1OMZ
1
EXTL2_MOUSE
A:
[195-229]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
V
H
A
-
L
-----
I
D
E
T
-
Q
N
C
D
D
I
A
M
N
F
L
V
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
45.33
25%
-33
- C6 -
4YZF
1
B3AT_HUMAN
A:
[381-887]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GL
V
R
D
I
R
R
R
Y
P
Y
Y
L
S
D
I
T
D
A
FS
P
Q
V
L
A
A
V
I
F
I
Y
F
A
A
L
S
P
A
I
T
F
G
G
L
L
G
E
K
T
RNQMG
V
S
E
L
L
I
S
T
A
V
Q
G
I
L
F
A
L
LGAQPL
L
V
V
G
F
S
G
P
L
L
V
F
E
E
A
F
F
S
F
C
E
T
N
GLE
Y
I
V
G
R
V
W
I
G
F
W
L
I
L
L
V
V
L
V
V
A
F
EGS
F
L
V
R
F
IS
R
Y
T
Q
E
I
F
S
F
L
I
S
L
I
F
I
Y
E
T
F
S
K
L
I
K
I
F
Q
D
H
P
L
Q
K
T
YLPNT
A
L
L
S
L
V
L
M
A
G
T
F
F
F
A
M
M
L
R
K
-
F
K
N
SSYFPG
K
L
R
R
-----------
V
I
G
D
F
G
V
P
I
S
I
L
I
-
M
-----
V
L
V
D
-
F
F
I
Q
D
T
Y
T
Q
K
L
S
V
----
P
D
G
F
K
V
V
I
H
-
P
-----
L
----------------
G
L
R
----------------------
S
--
E
F
P
I
W
M
M
F
A
S
A
L
P
A
L
L
V
F
I
L
I
F
L
E
S
Q
I
T
T
L
I
V
S
KPERKMVKGSG
F
H
L
D
L
L
L
V
V
G
M
G
G
V
A
A
L
F
G
M
P
W
L
S
AT
T
V
R
S
V
T
H
A
N
A
L
TVMI
Q
E
V
K
E
Q
R
I
S
G
L
L
V
A
V
L
V
G
L
S
ILM
E
P
I
L
S
R
IP
L
A
V
L
F
G
I
F
L
Y
M
G
V
T
S
L
SGI
Q
L
F
D
R
I
L
L
L
F
KPPKYHPDV
P
Y
V
K
R
V
K
T
W
R
M
H
L
F
T
G
I
Q
I
I
C
L
A
V
L
W
V
V
K
S
T
PASLA
L
P
F
V
L
I
L
T
V
P
L
R
R
V
L
L
P
L
I
FR
N
V
E
L
Q
C
L
D
16
HHSearch
45.10
11%
-54
- C7 -
2FB5
-
?
A:
[9-72]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
L
S
E
E
L
K
I
Q
-
T
K
Q
------
M
I
E
I
-----------
A
E
K
E
---
L
S
I
M
R
N
-
A
-----
I
D
K
E
-
D
E
C
--
I
L
C
K
M
E
D
I
----
H
H
M
L
A
N
V
Q
T
-
L
-----
A
----------------
A
T
Y
Y
I
Q
A
Y
-------
L
S
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
43.36
15%
-62
- C7 -
2F6M
2
VPS28_YEAST
B:
[3-109]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
I
S
Q
L
F
H
D
E
V
P
L
-
F
D
N
------
S
I
T
S
-----------
K
D
K
E
---
V
I
E
T
L
S
-
E
-----
I
Y
S
I
-
V
I
T
L
D
H
V
E
K
A
Y
L
K
DSID
D
T
Q
Y
T
N
T
V
D
-
K
-----
L
----------------
L
K
Q
F
K
V
Y
L
N
S
Q
N
K
E
E
I
N
K
H
F
Q
S
I
-
E
A
--
F
A
D
T
Y
N
I
T
A
S
N
A
I
T
R
L
E
R
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------