@TOME V2.3
(Nov 2016)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : Rv0248c: (2016-04-20 )
MVEVERHSYDVVVIGAGGAGLRAVIEARERGLKVAVVCKSLFGKAHTVMAEGGCAAAMGNANPKDNWKTHFGDTMRGGKFLNNWRMAELHAKEAPDRVWELETYGALFDRTDDGRISQRNFGGHTYPRLAHVGDRTGLELIRTLQQKVVSLQQEDHAELGDYEARIKVFAECTITELLKDQGAIAGAFGYWRESGRFIVFEAPAVVLATGGIGKSFKVTSNSWEYTGDGHALALRAGATLINMEFVQFHPTGMVWPPSVKGILVTEGVRGDGGVLKNSENSRFMFDYIPPVFKGQYAETEEEADQWLKDNDSARRTPDLLPRDEVARAINSEVKAGRGTPHGGVYLDIASRLTPAEIKRRLPSMYHQFKELAEVDITTQAMEVGPTCHYVMGGVEVDADTGAATVPGLFAAGECAGGMHGSNRLGGNSLSDLLVFGRRAGLGAADYVRALSSRPAVSAEAIDAAAQQALSPFEGPKDGSAPENPYALHMDLQYVMNDLVGIIRNADEISRALTLLAELWSRYHNVLVEGHRQYNPGWNLSIDLRNMLLVSECVARAALQRTESRGGHTRDDHPGMDPNWRRILLVCRATETMGTGGSGSGDSNCHINVTQQLQTPMRPDLLELFEISELEKYYTDEELAEHPGRRG

Atome Classification :

(49 SA) .........10........20........30-.--........40........50........60--.--.----......70........80........90........100.......110..---------------------...---------------------..-------120..-------..--------.--------..130--.......140.......-150.......160.......170.......180........190.......200.......210......------------.220.......230.....-..240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......-----340-...---......350.......--360--.......370-----..--------------.....380.......390.....--------..400-------.---------..---------.....410...-.-...420.......430.......440.......450.....-..--460.......470.......480.......490.......500.......510.......520...-....-530.....--...----540.......550.......560.......570-...-.-..-----------------.-.580.......590.------------------......600.......610..---......620.......630.......640---------....-
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MVEVERHSYDVVVIGAGGAGLRAVIEARER--G--LKVAVVCKSLFGKAHTVMAEGGCAAAMGNA--N--P----KDNWKTHFGDTMRGGKFLNNWRMAELHAKEAPDRVWELETYGALFDRTDDG---------------------RIS---------------------QR-------NFGGH-------TY--------P--------RLAHV--GDRTGLELIRTLQQKVV-SLQQEDHAELGDYEARIKVFAECTITELLKDQ-GAIAGAFGYWRESGRFIVFEAPAVVLATGGIGKSFKV------------TSNSWEYTGDGHALALRAG-ATLINMEFVQFHPTGMVWPPSVKGILVTEGVRGDGGVLKNSENSRFMFDYIPPVFKGQYAETEEEADQWLKDNDSARRTPDLLPRDEVARAINSEVKAGRGT-----P---HGG---VYLDIASRLTPAEIKR--RLP--SMYHQFKELA-----EV--------------DITTQAMEVGPTCHYVMGGVEVD--------ADTG--------A---------AT---------VPGLFAAGECA-G-GMHGSNRLGGNSLSDLLVFGRRAGLGAADYVRALSSRPAVS-AE--AIDAAAQQALSPFEGPKDGSAPENPYALHMDLQYVMNDLVGIIRNADEISRALTLLAELWSRYHNV-LVEG-H-RQYNPG--WNL----SIDLRNMLLVSECVARAALQRTESRGGHTRDD--HPG-M-DP-----------------N-WRRILLVCRATETMG------------------TGGSGSGDSNCHINVTQQ-LQ---TPMRPDLLELFEISELEKYYTDEELAEHP---------GRRG-
103 HHSearch 94.5236% -73 * C3 *2H88 SDHA_CHICK A:[14-589] ---VVDHEFDAVVVGAGGAGLRAAFGLSEA--G--FNTACVTKLFPTRSHTVAAQGGINAALGNM--E-------DDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPAAVIELENYGMPFSRTEEG---------------------KIY---------------------QR-------AFGGQ-------SLQFGKGGQAH--------RCCCV--ADRTGHSLLHTLYGRSL-RYD-------------TSYFVEYFALDLLMEN-GECRGVIALCIEDGTIHRFRAKNTVIATGGYGRTYFS------------CTSAHTSTGDGTAMVTRAG-LPCQDLEFVQFHPTGIYGA----GCLITEGCRGEGGILINSQGERFMERYAPVA-------------------------KDLASRDVVSRSMTIEIREGRGCGP---E---KDH---VYLQL-HHLPPQQLAT--RLP--GISETAMIFA-----GV--------------DVTKEPIPVLPTVHYNMGGIPTN--------YKGQVITHVNGED---------KV---------VPGLYACGEAA-SASVHGANRLGANSLLDLVVFGRACALTIAETCKPGEPVPSIK-PN--AGEESVANLDKLR----FADGTIRTSEARLNMQKTMQSHAAVFRTGSILQEGCEKLSQIYRDLAHL-KTFDRG-IVWNTD--LVE----TLELQNLMLCALQTIYGAEARKESRGAHARED--YKL-R-IDEFDYSKPLQGQQKRPFEEHWRKHTLSYVDV-----------------------------------------------------------------------------------------
104 HHSearch 92.4838% -74 - C3 -2WDQ SDHA_ECOLI A:[3-563] ---LPVREFDAVVIGAGGAGMRAALQISQS--G--QTCALLSKVFPTRSHTVSAQGGITVALGNT-----H----EDNWEWHMYDTVKGSDYIGDQDAIEYMCKTGPEAILELEHMGLPFSRLDDG---------------------RIY---------------------QR-------PFGGQSKNFGGEQA--------A--------RTAAA--ADRTGHALLHTLYQQNL-KNH-------------TTIFSEWYALDLVKNQDGAVVGCTALCIETGEVVYFKARATVLATGGAGRIYQS------------TTNAHINTGDGVGMAIRAG-VPVQDMEMWQFHPTGIAGA----GVLVTEGCRGEGGYLLNKHGERFMERYAPNA-------------------------KDLAGRDVVARSIMIEIREGRGC-----DGPWGPH---AKLKL-DHLGKEVLES--RLP--GILELSRTFA-----HV--------------DPVKEPIPVIPTCHYMMGGIPTK--------VTGQ--------ALTVNEKGEDVV---------VPGLFAVGEIA-CVSVHGANRLGGNSLLDLVVFGRAAGLHLQESIAEQGALRDAS-ES--DVEASLDRLNRWN----NNRNGEDPVAIRKALQECMQHNFSVFREGDAMAKGLEQLKVIRERLKNA-RLDDTS-SEFNTQ--RVE----CLELDNLMETAYATAVSANFRTESRGAHSRFD--FPD-R-DD-----------------ENWLCHSLYLPES-----------------------------------------------------------------------------------------
124 Fugue 91.2331% -61 - C3 -1E7P FRDA_WOLSU A:[1-655] ---MKVQYCDSLVIGGGLAGLRAAVATQQK--G--LSTIVLSLIPVKRSHSAAAQGGMQASLGNS--KMSD----GDNEDLHFMDTVKGSDWGCDQKVARMFVNTAPKAIRELAAWGVPWTRIHKGDRMAIINAQKTTITEEDFRHGLIH---------------------SR-------DFGGT-------KK--------W--------RTCYT--ADATGHTMLFAVANECL-KLG-------------VSIQDRKEAIALIHQD-GKCYGAVVRDLVTGDIIAYVAKGTLIATGGYGRIYKN------------TTNAVVCEGTGTAIALETGIAQLGNMEAVQFHPTPLFPS----GILLTEGCRGDGGILRDVDGHRFMPDYEP-------------------------EKKELASRDVVSRRMIEHIRKGKGV-----Q---SPYGQHLWLDI-SILGRKHIET--NLR--DVQEICEYFA-----GI--------------DPAEKWAPVLPMQHYSMGGIRTD--------YR-G--------E---------AK---------LKGLFSAGEAA-CWDMHGFNRLGGNSVSEAVVAGMIVGEYFAEHCAN--TQVDLE-TK--TLEKFVKGQEAYMKSLVESKGTEDVFKIKNRMKDVMDDNVGIFRDGPHLEKAVKELEELYKKSKNV-GIKN-KRLHANPE--LEE----AYRVPMMLKVALCVAKGALDRTESRGAHNRED--YPKRD-DI-----------------N-WLNRTLASWPNPEQTLPTLEYEALDVNEMEIAPGYRGYGAKGNYIENPLSV-KR---QEEIDKIQSELEAAGKDRHAIQEALMPYELPAKYKARNERLGD
105 HHSearch 91.0634% -73 - C3 -1KF6 FRDA_ECOLI A:[2-560] ----QTFQADLAIVGAGGAGLRAAIAAAQANPN--AKIALISKVYPMRSHTVAAEGGSAAVAQ-------D----HDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDG---------------------SVN---------------------VR-------RFGGM-------KI--------E--------RTWFA--ADKTGFHMLHTLFQTSLQFPQ-------------IQRFDEHFVLDILVDD-GHVRGLVAMNMMEGTLVQIRANAVVMATGGAGRVYRY------------NTNGGIVTGDGMGMALSHG-VPLRDMEFVQYHPTGLPGS----GILMTEGCRGEGGILVNKNGYRYLQDYGMGPET---PL---------GEPK--NKYMELGPRDKVSQAFWHEWRKGNTISTP--R---GDV---VYLDL-RHLGEKKLHE--RLP--FICELAKAYV-----GV--------------DPVKEPIPVRPTAHYTMGGIETD--------QNCE------------------TR---------IKGLFAVGECS-SVGLHGANRLGSNSLAELVVFGRLAGEQATERAATAGNGNEAAIEA--QAAGVEQRLKDLV----NQDGGENWAKIRDEMGLAMEEGCGIYRTPELMQKTIDKLAELQERFKRV-RITDTS-SVFNTD--LLY----TIELGHGLNVAECMAHSAMARKESRGAHQRLDEGCTE-R-DD-----------------VNFLKHTLAFRDADG---------------------------------------------------------------------------------------
102 HHSearch 90.9332% -70 - C3 -2BS2 FRDA_WOLSU A:[2-599] ----KVQYCDSLVIGGGLAGLRAAVATQQK--G--LSTIVLSLIPVKRSHSAAAQGGMQASLGNSKMS--D----GDNEDLHFMDTVKGSDWGCDQKVARMFVNTAPKAIRELAAWGVPWTRIHKG---------------------DRMAIINAQKTTITEEDFRHGLIHSR-------DFGGT-------KK--------W--------RTCYT--ADATGHTMLFAVANECL-KLG-------------VSIQDRKEAIALIHQD-GKCYGAVVRDLVTGDIIAYVAKGTLIATGGYGRIYKN------------TTNAVVCEGTGTAIALETGIAQLGNMEAVQFHPTPLFPS----GILLTEGCRGDGGILRDVDGHRFMPDYEPE-------------------------KKELASRDVVSRRMIEHIRKGKGVQSP--Y---GQH---LWLDI-SILGRKHIET--NLR--DVQEICEYFA-----GI--------------DPAEKWAPVLPMQHYSMGGIRTD--------YRGE------------------AK---------LKGLFSAGEAA-CWDMHGFNRLGGNSVSEAVVAGMIVGEYFAEHCANTQVDLETK-TLEKFVKGQEAYM-KSLV---ESKGTEDVFKIKNRMKDVMDDNVGIFRDGPHLEKAVKELEELYKKSKNV-GIKNKR-LHANPE--LEE----AYRVPMMLKVALCVAKGALDRTESRGAHNRED--YPK-R-DD-----------------INWLNRTLASWPNPEQT------------------L-----------PTLEYEALDVNEMEIAPGYRGYGA-------------------------------
123 Fugue 90.7733% -69 - C3 -1L0V FRDA_ECOLI A:[1-577] ---MQTFQADLAIVGAGGAGLRAAIAAAQA--NPNAKIALISKVYPMRSHTVAAEGGSAAVA-----Q--D----HDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGCPWSRRPDG---------------------SVN---------------------VR-------RFGGM-------KI--------E--------RTWFA--ADKTGFHMLHTLFQTSL-Q---FPQIQRFDEHFVLDILVDD----------GHVRGLVAMNMMEGTLVQIRANAVVMATGGAGRVYRY------------NTNGGIVTGDGMGMALSHG-VPLRDMEFVQYHPTGLPG----SGILMTEGCRGEGGILVNKNGYRYLQDY--------------GMGPETPLGEPKNKYMELGPRDKVSQAFWHEWRKGNTI-----S---TPRGDVVYLDL-RHLGEKKLHE--RLP--FICELAKAYV-----GV--------------DPVKEPIPVRPTAHYTMGGIETD--------QN-C--------E---------TR---------IKGLFAVGECS-SVGLHGANRLGSNSLAELVVFGRLAGEQATERAATAGNGNEAA-IE--AQAAGVEQRLKDLVNQDGG---ENWAKIRDEMGLAMEEGCGIYRTPELMQKTIDKLAELQERFKRV-RITD-TSSVFNTD--LLY----TIELGHGLNVAECMAHSAMARKESRGAHQRLD--EGC-T-ER-----------------D-DVNFLKHTLAFR--------------------------DADGTTRLEYSDV-KI---TTLPPA-------------------------------------
25 PsiBlast_CBE 89.1435% -69 - C3 -2WS3 SDHA_ECOLI I:[8-566] --------FDAVVIGAGGAGMRAALQISQS--G--QTCALLSKVFPTRSHTVSAQGGITVALGNT--H-------EDNWEWHMYDTVKGSDYIGDQDAIEYMCKTGPEAILELEHMGLPFSRLDDG---------------------RIY---------------------QRPFGGQSKNFGGE-------QA--------A--------RTAAA--ADRTGHALLHTLYQQ--------------NLKNHTTIFSEWYALDLVKNQDGAVVGCTALCIETGEVVYFKARATVLATGGAGRIYQS------------TTNAHINTGDGVGMAIRAG-VPVQDMEMWQFHPTGI----AGAGVLVTEGCRGEGGYLLNKHGERFMERYAP-------------------------NAKDLAGRDVVARSIMIEIREGRGCDGPWGP---HAK---LKLD---HLGKEVLES--RLP--GILELSRTFA-----HV--------------DPVKEPIPVIPTCHYMMGGIPTK--------VTGQ--------A---------LTVNEKGEDVVVPGLFAVGEIA-CVSVHGANRLGGNSLLDLVVFGRAAGL----HLQESIAEQGAL-RD--ASESDVEASLDRLNRWNNNRNGEDPVAIRKALQECMQHNFSVFREGDAMAKGLEQLKVIRERLKNARLDDT-S-SEFNTQ--RVE----CLELDNLMETAYATAVSANFRTESRGAHSRFD--FPD-RDDE-----------------N-WLCHSLYLPESESM--------------------------------------------------------------------------------------
9 PsiBlast_PDB 89.1435% -67 - C3 -2WU2 SDHA_ECOLI A:[8-566] --------FDAVVIGAGGAGMRAALQISQS--G--QTCALLSKVFPTRSHTVSAQGGITVALGNT--H-------EDNWEWHMYDTVKGSDYIGDQDAIEYMCKTGPEAILELEHMGLPFSRLDDG---------------------RIY---------------------QRPFGGQSKNFGGE-------QA--------A--------RTAAA--ADRTGHALLHTLYQQ--------------NLKNHTTIFSEWYALDLVKNQDGAVVGCTALCIETGEVVYFKARATVLATGGAGRIYQS------------TTNAHINTGDGVGMAIRAG-VPVQDMEMWQFHPTGI----AGAGVLVTEGCRGEGGYLLNKHGERFMERYAP-------------------------NAKDLAGRDVVARSIMIEIREGRGCDGPWGP---HAK---LKLD---HLGKEVLES--RLP--GILELSRTFA-----HV--------------DPVKEPIPVIPTCHYMMGGIPTK--------VTGQ--------A---------LTVNEKGEDVVVPGLFAVGEIA-CVSVHGANRLGGNSLLDLVVFGRAAGL----HLQESIAEQGAL-RD--ASESDVEASLDRLNRWNNNRNGEDPVAIRKALQECMQHNFSVFREGDAMAKGLEQLKVIRERLKNARLDDT-S-SEFNTQ--RVE----CLELDNLMETAYATAVSANFRTESRGAHSRFD--FPD-RDDE-----------------N-WLCHSLYLPESESM--------------------------------------------------------------------------------------
7 PsiBlast_PDB 89.1235% -67 - C3 -2WP9 SDHA_ECOLI A:[8-566] --------FDAVVIGAGGAGMRAALQISQS--G--QTCALLSKVFPTRSHTVSAQGGITVALGNT--H-------EDNWEWHMYDTVKGSDYIGDQDAIEYMCKTGPEAILELEHMGLPFSRLDDG---------------------RIY---------------------QRPFGGQSKNFGGE-------QA--------A--------RTAAA--ADRTGHALLHTLYQQ--------------NLKNHTTIFSEWYALDLVKNQDGAVVGCTALCIETGEVVYFKARATVLATGGAGRIYQS------------TTNAHINTGDGVGMAIRAG-VPVQDMEMWQFHPTGI----AGAGVLVTEGCRGEGGYLLNKHGERFMERYAP-------------------------NAKDLAGRDVVARSIMIEIREGRGCDGPWGP---HAK---LKLD---HLGKEVLES--RLP--GILELSRTFA-----HV--------------DPVKEPIPVIPTCHYMMGGIPTK--------VTGQ--------A---------LTVNEKGEDVVVPGLFAVGEIA-CVSVHGANRLGGNSLLDLVVFGRAAGL----HLQESIAEQGAL-RD--ASESDVEASLDRLNRWNNNRNGEDPVAIRKALQECMQHNFSVFREGDAMAKGLEQLKVIRERLKNARLDDT-S-SEFNTQ--RVE----CLELDNLMETAYATAVSANFRTESRGAHSRFD--FPD-RDDE-----------------N-WLCHSLYLPESESM--------------------------------------------------------------------------------------
8 PsiBlast_PDB 89.0235% -70 - C3 -2WS3 SDHA_ECOLI A:[8-566] --------FDAVVIGAGGAGMRAALQISQS--G--QTCALLSKVFPTRSHTVSAQGGITVALGNT--H-------EDNWEWHMYDTVKGSDYIGDQDAIEYMCKTGPEAILELEHMGLPFSRLDDG---------------------RIY---------------------QRPFGGQSKNFGGE-------QA--------A--------RTAAA--ADRTGHALLHTLYQQ--------------NLKNHTTIFSEWYALDLVKNQDGAVVGCTALCIETGEVVYFKARATVLATGGAGRIYQS------------TTNAHINTGDGVGMAIRAG-VPVQDMEMWQFHPTGI----AGAGVLVTEGCRGEGGYLLNKHGERFMERYAP-------------------------NAKDLAGRDVVARSIMIEIREGRGCDGPWGP---HAK---LKLD---HLGKEVLES--RLP--GILELSRTFA-----HV--------------DPVKEPIPVIPTCHYMMGGIPTK--------VTGQ--------A---------LTVNEKGEDVVVPGLFAVGEIA-CVSVHGANRLGGNSLLDLVVFGRAAGL----HLQESIAEQGAL-RD--ASESDVEASLDRLNRWNNNRNGEDPVAIRKALQECMQHNFSVFREGDAMAKGLEQLKVIRERLKNARLDDT-S-SEFNTQ--RVE----CLELDNLMETAYATAVSANFRTESRGAHSRFD--FPD-RDDE-----------------N-WLCHSLYLPESESM--------------------------------------------------------------------------------------
29 PsiBlast_CBE 89.0035% -68 - C3 -2WDV SDHA_ECOLI I:[8-566] --------FDAVVIGAGGAGMRAALQISQS--G--QTCALLSKVFPTRSHTVSAQGGITVALGNT--H-------EDNWEWHMYDTVKGSDYIGDQDAIEYMCKTGPEAILELEHMGLPFSRLDDG---------------------RIY---------------------QRPFGGQSKNFGGE-------QA--------A--------RTAAA--ADRTGHALLHTLYQQ--------------NLKNHTTIFSEWYALDLVKNQDGAVVGCTALCIETGEVVYFKARATVLATGGAGRIYQS------------TTNAHINTGDGVGMAIRAG-VPVQDMEMWQFHPTGI----AGAGVLVTEGCRGEGGYLLNKHGERFMERYAP-------------------------NAKDLAGRDVVARSIMIEIREGRGCDGPWGP---HAK---LKLD---HLGKEVLES--RLP--GILELSRTFA-----HV--------------DPVKEPIPVIPTCHYMMGGIPTK--------VTGQ--------A---------LTVNEKGEDVVVPGLFAVGEIA-CVSVHGANRLGGNSLLDLVVFGRAAGL----HLQESIAEQGAL-RD--ASESDVEASLDRLNRWNNNRNGEDPVAIRKALQECMQHNFSVFREGDAMAKGLEQLKVIRERLKNARLDDT-S-SEFNTQ--RVE----CLELDNLMETAYATAVSANFRTESRGAHSRFD--FPD-RDDE-----------------N-WLCHSLYLPESESM--------------------------------------------------------------------------------------
27 PsiBlast_CBE 88.9835% -68 - C3 -2WP9 SDHA_ECOLI I:[8-566] --------FDAVVIGAGGAGMRAALQISQS--G--QTCALLSKVFPTRSHTVSAQGGITVALGNT--H-------EDNWEWHMYDTVKGSDYIGDQDAIEYMCKTGPEAILELEHMGLPFSRLDDG---------------------RIY---------------------QRPFGGQSKNFGGE-------QA--------A--------RTAAA--ADRTGHALLHTLYQQ--------------NLKNHTTIFSEWYALDLVKNQDGAVVGCTALCIETGEVVYFKARATVLATGGAGRIYQS------------TTNAHINTGDGVGMAIRAG-VPVQDMEMWQFHPTGI----AGAGVLVTEGCRGEGGYLLNKHGERFMERYAP-------------------------NAKDLAGRDVVARSIMIEIREGRGCDGPWGP---HAK---LKLD---HLGKEVLES--RLP--GILELSRTFA-----HV--------------DPVKEPIPVIPTCHYMMGGIPTK--------VTGQ--------A---------LTVNEKGEDVVVPGLFAVGEIA-CVSVHGANRLGGNSLLDLVVFGRAAGL----HLQESIAEQGAL-RD--ASESDVEASLDRLNRWNNNRNGEDPVAIRKALQECMQHNFSVFREGDAMAKGLEQLKVIRERLKNARLDDT-S-SEFNTQ--RVE----CLELDNLMETAYATAVSANFRTESRGAHSRFD--FPD-RDDE-----------------N-WLCHSLYLPESESM--------------------------------------------------------------------------------------