@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv0478: (2016-04-23 )
MLGQPTRAQLAALVDHTLLKPETTRADVAALVAEAAELGVYAVCVSPSMVPVAVQAGGVRVAAVTGFPSGKHVSSVKAHEAAAALASGASEIDMVIDIGAALCGDIDAVRSDIEAVRAAAAGAVLKVIVESAVLLGQSNAHTLVDACRAAEDAGADFVKTSTGCHPAGGATVRAVELMAETVGPRLGVKASGGIRTAADAVAMLNAGATRLGLSGTRAVLDGLS
Atome Classification :
(37 SA)
--.........10........20........30.......--.40......-..50-..------...----.----.------.60.--.......70........80........90....--....100.......110.---...--...--120-........130.......140..-.....150.......160.......170.....--..180----..---.-----.---....190.......200....------------...210..---------..-...220..------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--MLGQ
P
T
R
A
Q
L
A
A
L
V
D
H
TLLKPET
T
R
A
D
V
A
A
L
V
A
E
A
A
EL--
G
V
Y
A
V
CVSP-S
M
V
P
-
V
A
------
V
QA----G----
G
------
V
R
V
A
--
A
V
TGFPSGKHV
S
S
V
K
A
H
E
A
A
A
A
L
ASGAS
E
I
D
M
V
--
I
D
I
G
A
A
L
CG
D
I
D
A
V
R
S
D
I
---
E
A
V
--
R
A
A
--
A
A
--
G
A
V
L
K
V
I
V
E
S
A
V
LLGQSN
A
H
T
L
V
-
D
A
C
R
A
A
E
DAGAD
F
V
KTSTGCHPAGGA
T
V
R
A
V
E
L
--
M
A
E
T-----VG---P-----R---LGVKASGGI
R
T
A
A
D
A
V
A
M
L
NA------------GATRLGLS---------
G
T
-
R
A
V
LDGLS------
1
PsiBlast_PDB
97.19
82%
-117
- C2 -
3NG3
2
DEOC_MYCA1
A:
[7-226]
------
P
T
R
A
Q
L
A
A
F
V
D
H
T
L
L
K
P
E
A
T
A
A
D
V
A
A
L
V
T
E
A
A
E
L
--
G
V
Y
A
V
C
V
S
P
-
P
M
V
P
-
A
A
------
V
Q
A
----
G
A-----------
R
V
A
--
S
V
A
G
F
P
S
G
K
H
V
S
A
V
K
A
H
E
A
A
L
A
V
A
S
G
A
A
E
I
D
M
V
--
I
D
V
G
A
A
L
A
G
D
L
D
G
V
R
A
D
I
---
A
A
V
--
R
G
A
--
V
G
--
G
A
V
L
K
V
I
V
E
S
S
A
L
L
A
L
A
D
E
H
T
L
V
-
R
V
C
R
A
A
E
D
A
G
A
D
F
V
K
T
S
T
G
F
H
P
S
G
G
A
S
V
R
A
V
A
L
--
M
A
E
A
-----
V
G
---
G
-----
R
---
L
G
V
K
A
S
G
G
I
R
T
A
A
D
A
L
A
M
L
D
A
------------
G
A
T
R
L
G
L
S
---------
G
T
-
R
A
V
L
D
G
L
-------
23
PsiBlast_CBE
96.38
82%
-115
- C2 -
3NG3
2
DEOC_MYCA1
B:
[7-226]
------
P
T
R
A
Q
L
A
A
F
V
D
H
T
L
L
K
P
E
A
T
A
A
D
V
A
A
L
V
T
E
A
A
E
L
--
G
V
Y
A
V
C
V
S
P
-
P
M
V
P
-
A
A
------
V
Q
A
-----------------
R
V
A
--
S
V
A
G
F
P
S
G
K
H
V
S
A
V
K
A
H
E
A
A
L
A
V
A
S
G
A
A
E
I
D
M
V
--
I
D
V
G
A
A
L
A
G
D
L
D
G
V
R
A
D
I
---
A
A
V
--
R
G
A
--
V
G
--
G
A
V
L
K
V
I
V
E
S
S
A
L
L
A
L
A
D
E
H
T
L
V
-
R
V
C
R
A
A
E
D
A
G
A
D
F
V
K
T
S
T
G
F
H
P
S
G
G
A
S
V
R
A
V
A
L
--
M
A
E
A
-----
V
G
---
G
-----
R
---
L
G
V
K
A
S
G
G
I
R
T
A
A
D
A
L
A
M
L
D
A
------------
G
A
T
R
L
G
L
S
---------
G
T
-
R
A
V
L
D
G
L
-------
21
PsiBlast_CBE
95.15
82%
-117
- C2 -
3NG3
2
DEOC_MYCA1
D:
[7-225]
------
P
T
R
A
Q
L
A
A
F
V
D
H
T
L
L
K
P
E
A
T
A
A
D
V
A
A
L
V
T
E
A
A
E
L
--
G
V
Y
A
V
C
V
S
P
-
P
M
V
P
-
A
A
------
V
Q
A
----
G
-----------
V
R
V
A
--
S
V
A
G
F
P
S
G
K
H
V
S
A
V
K
A
H
E
A
A
L
A
V
A
S
G
A
A
E
I
D
M
V
--
I
D
V
G
A
A
L
A
G
D
L
D
G
V
R
A
D
I
---
A
A
V
--
R
G
A
--
V
G
--
G
A
V
L
K
V
I
V
E
S
S
A
L
L
A
L
A
D
E
H
T
L
V
-
R
V
C
R
A
A
E
D
A
G
A
D
F
V
K
T
S
T
G
F
H
P
S
G
G
A
S
V
R
A
V
A
L
--
M
A
E
A
-----
V
G
---
G
-----
R
---
L
G
V
K
A
S
G
G
I
R
T
A
A
D
A
L
A
M
L
D
A
------------
G
A
T
R
L
G
L
S
---------
G
T
-
R
A
V
L
D
G
--------
22
PsiBlast_CBE
93.93
82%
-117
- C2 -
3NG3
4
DEOC_MYCA1
C:
[7-226]
------
P
T
R
A
Q
L
A
A
F
V
D
H
T
L
L
K
P
E
A
T
A
A
D
V
A
A
L
V
T
E
A
A
E
L
--
G
V
Y
A
V
C
V
S
P
-
P
M
V
P
-
A
A
------
V
Q
A
----
G
A---
G
------
V
R
V
A
--
S
V
A
G
F
P
S
G
K
H
V
S
A
V
K
A
H
E
A
A
L
A
V
A
S
G
A
A
E
I
D
M
V
--
I
D
V
G
A
A
L
A
G
D
L
D
G
V
R
A
D
I
---
A
A
V
--
R
G
A
--
V
G
--
G
A
V
L
K
V
I
V
E
S
S
A
L
L
A
L
A
D
E
H
T
L
V
-
R
V
C
R
A
A
E
D
A
G
A
D
F
V
K
T
S
T
G
F
H
P
S
G
G
A
S
V
R
A
V
A
L
--
M
A
E
A
-----
V
G
---
G
-----
R
---
L
G
V
K
A
S
G
G
I
R
T
A
A
D
A
L
A
M
L
D
A
------------
G
A
T
R
L
G
L
S
---------
G
T
-
R
A
V
L
D
G
L
-------
24
PsiBlast_CBE
93.17
70%
-119
- C2 -
3NDO
3
?
B:
[9-228]
-------
T
R
A
Q
V
A
A
L
V
D
H
T
L
L
K
P
E
A
T
P
S
D
V
T
A
L
V
D
E
A
A
D
L
--
G
V
F
A
V
C
V
S
P
-
P
L
V
S
-
V
A
AG----
V
A
P
----
S
----
G
------
L
A
I
A
--
A
V
A
G
F
P
S
G
K
H
V
P
G
I
K
A
T
E
A
E
L
A
V
A
A
G
A
T
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I
D
M
V
--
I
D
V
G
A
A
L
A
G
D
L
D
A
V
S
A
D
I
---
T
A
V
--
R
K
A
--
V
R
--
A
A
T
L
K
V
I
V
E
S
A
A
L
L
E
F
S
G
E
P
L
L
A
-
D
V
C
R
V
A
R
D
A
G
A
D
F
V
K
T
S
T
G
F
H
P
S
G
G
A
S
V
Q
A
V
E
I
--
M
A
R
T
-----
V
G
---
E
-----
R
---
L
G
V
K
A
S
G
G
I
R
T
A
E
Q
A
A
A
M
L
D
A
------------
G
A
T
R
L
G
L
S
---------
G
S
-
R
A
V
L
D
G
F
-------
56
HHSearch
93.12
70%
-117
- C2 -
3NDO
4
?
A:
[7-228]
-----
D
H
T
R
A
Q
V
A
A
L
V
D
H
T
L
L
K
P
E
A
T
P
S
D
V
T
A
L
V
D
E
A
A
D
L
--
G
V
F
A
V
C
V
S
P
-
P
L
V
S
-
V
A
------
A
G
V
AP--
S
----
G
------
L
A
I
A
--
A
V
A
G
F
P
S
G
K
H
V
P
G
I
K
A
T
E
A
E
L
A
V
A
A
G
A
T
E
I
D
M
V
--
I
D
V
G
A
A
L
A
G
D
L
D
A
V
S
A
D
I
---
T
A
V
--
R
K
A
--
V
R
--
A
A
T
L
K
V
I
V
E
S
A
A
L
L
E
F
S
G
E
P
L
L
A
-
D
V
C
R
V
A
R
D
A
G
A
D
F
V
K
T
S
T
G
F
H
P
S
G
G
A
S
V
Q
A
V
E
I
--
M
A
R
T
-----
V
G
---
E
-----
R
---
L
G
V
K
A
S
G
G
I
R
T
A
E
Q
A
A
A
M
L
D
A
------------
G
A
T
R
L
G
L
S
---------
G
S
-
R
A
V
L
D
G
F
-------
2
PsiBlast_PDB
92.59
70%
-117
- C2 -
3NDO
4
?
A:
[9-228]
-------
T
R
A
Q
V
A
A
L
V
D
H
T
L
L
K
P
E
A
T
P
S
D
V
T
A
L
V
D
E
A
A
D
L
--
G
V
F
A
V
C
V
S
P
-
P
L
V
S
-
V
A
A
G
----
V
A
P
----
S
----
G
------
L
A
I
A
--
A
V
A
G
F
P
S
G
K
H
V
P
G
I
K
A
T
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A
E
L
A
V
A
A
G
A
T
E
I
D
M
V
--
I
D
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G
A
A
L
A
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D
L
D
A
V
S
A
D
I
---
T
A
V
--
R
K
A
--
V
R
--
A
A
T
L
K
V
I
V
E
S
A
A
L
L
E
F
S
G
E
P
L
L
A
-
D
V
C
R
V
A
R
D
A
G
A
D
F
V
K
T
S
T
G
F
H
P
S
G
G
A
S
V
Q
A
V
E
I
--
M
A
R
T
-----
V
G
---
E
-----
R
---
L
G
V
K
A
S
G
G
I
R
T
A
E
Q
A
A
A
M
L
D
A
------------
G
A
T
R
L
G
L
S
---------
G
S
-
R
A
V
L
D
G
F
-------
57
HHSearch
84.62
45%
-115
- C2 -
3NGJ
3
?
A:
[22-238]
------
M
D
K
A
T
L
A
K
Y
I
D
H
T
L
L
K
A
D
A
T
E
E
Q
I
R
K
L
C
S
E
A
A
E
Y
--
K
F
A
S
V
C
V
N
P
-
T
W
V
P
-
L
C
------
A
E
L
L
---
K
GT--
G
------
V
K
V
C
--
T
V
I
G
F
P
L
G
A
T
P
S
E
V
K
A
Y
E
T
K
V
A
V
E
Q
G
A
E
E
V
D
M
V
--
I
N
I
G
M
V
K
A
K
K
Y
D
D
V
E
K
D
V
---
K
A
V
--
V
D
A
--
S
G
--
K
A
L
T
K
V
I
I
E
C
C
Y
L
T
N
----
E
E
K
V
-
E
V
C
K
R
C
V
A
A
G
A
E
Y
V
K
T
S
T
G
F
G
T
-
H
G
A
T
P
E
D
V
K
L
--
M
K
D
T
-----
V
G
---
D
-----
K
---
A
L
V
K
A
A
G
G
I
R
T
F
D
D
A
M
K
M
I
N
N
------------
G
A
S
R
I
G
A
S
---------
A
G
-
I
A
I
L
N
G
I
-------
54
HHSearch
84.22
43%
-109
* C2 *
3R12
3
DEOC_THEMA
A:
[39-254]
-------
G
I
E
D
V
K
S
A
I
E
H
T
N
L
K
P
F
A
T
P
D
D
I
K
K
L
C
L
E
A
R
E
N
--
R
F
H
G
V
C
V
N
P
-
C
Y
V
K
-
L
A
------
R
E
E
L
EG-
T
----
D
------
V
K
V
V
--
T
V
V
G
F
P
L
G
A
N
E
T
R
T
K
A
H
E
A
I
F
A
V
E
S
G
A
D
E
I
D
M
V
--
I
N
V
G
M
L
K
A
K
E
W
E
Y
V
Y
E
D
I
---
R
S
V
--
V
E
S
--
V
K
--
G
K
V
V
K
V
I
I
E
T
C
Y
L
D
T
----
E
E
K
I
-
A
A
C
V
I
S
K
L
A
G
A
H
F
V
K
T
S
T
G
F
G
T
-
G
G
A
T
A
E
D
V
H
L
--
M
K
W
I
-----
V
G
---
D
-----
E
---
M
G
V
K
A
S
G
G
I
R
T
F
E
D
A
V
K
M
I
M
Y
------------
G
A
D
R
I
G
T
S
---------
S
G
-
V
K
I
V
Q
G
G
-------
5
PsiBlast_PDB
83.99
45%
-114
- C2 -
4XBK
-
?
A:
[40-255]
-------
T
T
E
Q
L
A
K
Y
I
D
H
T
N
L
K
A
D
A
T
E
A
D
I
K
Q
T
C
D
E
A
K
K
F
--
N
T
A
S
V
C
V
N
S
-
Y
W
I
P
F
V
T
------
E
Q
L
----
K
----
G
------
T
D
V
N
P
I
A
V
V
G
F
P
L
G
A
M
A
T
E
S
E
I
F
E
A
T
T
A
I
D
Q
G
A
E
E
I
D
M
V
--
L
N
V
G
E
L
K
G
G
N
D
E
K
V
L
A
D
I
---
Q
G
L
--
A
D
A
V
H
A
K
--
G
K
I
L
K
V
I
L
E
N
A
L
L
----
T
K
D
E
I
V
-
R
A
C
Q
L
S
E
K
A
G
A
D
F
V
K
T
S
T
G
F
S
T
S
G
-
A
K
V
E
D
V
K
L
--
M
R
E
T
-----
V
G
---
D
-----
R
---
L
G
V
K
A
S
G
G
I
H
S
R
E
E
A
L
A
M
I
D
A
------------
G
A
S
R
M
G
V
S
---------
A
T
-
V
A
I
L
T
---------
25
PsiBlast_CBE
83.71
43%
-109
- C2 -
3NGJ
5
?
D:
[20-238]
----
G
S
M
D
K
A
T
L
A
K
Y
I
D
H
T
L
L
K
A
D
A
T
E
E
Q
I
R
K
L
C
S
E
A
A
E
Y
--
K
F
A
S
V
C
V
N
P
-
T
W
V
P
-
L
C
AEL---
L
K
G
----
T
----
G
------
V
K
V
C
--
T
V
I
G
F
P
L
G
A
T
P
S
E
V
K
A
Y
E
T
K
V
A
V
E
Q
G
A
E
E
V
D
M
V
--
I
N
I
G
M
V
K
A
K
K
Y
D
D
V
E
K
D
V
---
K
A
V
--
V
D
A
--
S
G
--
K
A
L
T
K
V
I
I
E
C
C
Y
L
T
N
E
E
K
----
V
-
E
V
C
K
R
C
V
A
A
G
A
E
Y
V
K
T
S
T
G
-
F
G
T
H
G
A
T
P
E
D
V
K
L
--
M
K
D
T
-----
V
G
---
D
-----
K
---
A
L
V
K
A
A
G
G
I
R
T
F
D
D
A
M
K
M
I
N
N
------------
G
A
S
R
I
G
A
S
---------
A
G
-
I
A
I
L
N
G
I
-------
4
PsiBlast_PDB
83.47
45%
-111
- C2 -
4XBS
-
?
A:
[4-219]
-------
T
T
E
Q
L
A
K
Y
I
D
H
T
N
L
K
A
D
A
T
E
A
D
I
K
Q
T
C
D
E
A
K
K
F
--
N
T
A
S
V
C
V
N
S
-
Y
W
I
P
F
V
T
------
E
Q
L
----
K
----
G
------
T
D
V
N
P
I
A
V
V
G
F
P
L
G
A
M
A
T
E
S
K
I
F
E
A
T
T
A
I
D
Q
G
A
E
E
I
D
M
V
--
L
N
V
G
E
L
K
G
G
N
D
E
K
V
L
A
D
I
---
Q
G
L
--
A
D
A
V
H
A
K
--
G
K
I
L
K
V
I
L
E
N
A
L
L
----
T
K
D
E
I
V
-
R
A
C
Q
L
S
E
K
A
G
A
D
F
V
K
T
S
T
G
F
S
T
S
G
-
A
K
V
E
D
V
K
L
--
M
R
E
T
-----
V
G
---
D
-----
R
---
L
G
V
K
A
S
G
G
I
H
S
R
E
E
A
L
A
M
I
D
A
------------
G
A
S
R
M
G
V
S
---------
A
T
-
V
A
I
L
T
---------
26
PsiBlast_CBE
83.36
43%
-108
- C2 -
3NGJ
5
?
C:
[20-238]
----
G
S
M
D
K
A
T
L
A
K
Y
I
D
H
T
L
L
K
A
D
A
T
E
E
Q
I
R
K
L
C
S
E
A
A
E
Y
--
K
F
A
S
V
C
V
N
P
-
T
W
V
P
-
L
C
A
E
L
---
L
K
G
----
T
----
G
------
V
K
V
C
--
T
V
I
G
F
P
L
G
A
T
P
S
E
V
K
A
Y
E
T
K
V
A
V
E
Q
G
A
E
E
V
D
M
V
--
I
N
I
G
M
V
K
A
K
K
Y
D
D
V
E
K
D
V
---
K
A
V
--
V
D
A
--
S
G
--
K
A
L
T
K
V
I
I
E
C
C
Y
L
T
N
E
E
K
----
V
-
E
V
C
K
R
C
V
A
A
G
A
E
Y
V
K
T
S
T
G
-
F
G
T
H
G
A
T
P
E
D
V
K
L
--
M
K
D
T
-----
V
G
---
D
-----
K
---
A
L
V
K
A
A
G
G
I
R
T
F
D
D
A
M
K
M
I
N
N
------------
G
A
S
R
I
G
A
S
---------
A
G
-
I
A
I
L
N
G
I
-------
27
PsiBlast_CBE
83.02
43%
-110
- C2 -
3NGJ
5
?
B:
[22-238]
------
M
D
K
A
T
L
A
K
Y
I
D
H
T
L
L
K
A
D
A
T
E
E
Q
I
R
K
L
C
S
E
A
A
E
Y
--
K
F
A
S
V
C
V
N
P
-
T
W
V
P
-
L
C
A
E
L
---
L
K
G
----
T
----
G
------
V
K
V
C
--
T
V
I
G
F
P
L
G
A
T
P
S
E
V
K
A
Y
E
T
K
V
A
V
E
Q
G
A
E
E
V
D
M
V
--
I
N
I
G
M
V
K
A
K
K
Y
D
D
V
E
K
D
V
---
K
A
V
--
V
D
A
--
S
G
--
K
A
L
T
K
V
I
I
E
C
C
Y
L
T
N
E
E
K
----
V
-
E
V
C
K
R
C
V
A
A
G
A
E
Y
V
K
T
S
T
G
-
F
G
T
H
G
A
T
P
E
D
V
K
L
--
M
K
D
T
-----
V
G
---
D
-----
K
---
A
L
V
K
A
A
G
G
I
R
T
F
D
D
A
M
K
M
I
N
N
------------
G
A
S
R
I
G
A
S
---------
A
G
-
I
A
I
L
N
G
I
-------
28
PsiBlast_CBE
82.93
45%
-110
- C2 -
4XBK
3
?
B:
[40-255]
-------
T
T
E
Q
L
A
K
Y
I
D
H
T
N
L
K
A
D
A
T
E
A
D
I
K
Q
T
C
D
E
A
K
K
F
--
N
T
A
S
V
C
V
N
S
-
Y
W
I
P
F
V
T
------
E
Q
L
----
K
----
G
------
T
D
V
N
PI
A
V
V
G
F
P
L
G
A
M
A
T
E
S
E
I
F
E
A
T
T
A
I
D
Q
G
A
E
E
I
D
M
V
--
L
N
V
G
E
L
K
G
G
N
D
E
K
V
L
A
D
I
---
Q
G
L
--
A
D
A
VH
A
K
--
G
K
I
L
K
V
I
L
E
N
A
L
L
----
T
K
D
E
I
V
-
R
A
C
Q
L
S
E
K
A
G
A
D
F
V
K
T
S
T
G
F
S
T
S
G
-
A
K
V
E
D
V
K
L
--
M
R
E
T
-----
V
G
---
D
-----
R
---
L
G
V
K
A
S
G
G
I
H
S
R
E
E
A
L
A
M
I
D
A
------------
G
A
S
R
M
G
V
S
---------
A
T
-
V
A
I
L
T
---------
3
PsiBlast_PDB
82.64
43%
-108
- C2 -
3NGJ
3
?
A:
[22-238]
------
M
D
K
A
T
L
A
K
Y
I
D
H
T
L
L
K
A
D
A
T
E
E
Q
I
R
K
L
C
S
E
A
A
E
Y
--
K
F
A
S
V
C
V
N
P
-
T
W
V
P
-
L
C
A
E
L
---
L
K
G
----
T
----
G
------
V
K
V
C
--
T
V
I
G
F
P
L
G
A
T
P
S
E
V
K
A
Y
E
T
K
V
A
V
E
Q
G
A
E
E
V
D
M
V
--
I
N
I
G
M
V
K
A
K
K
Y
D
D
V
E
K
D
V
---
K
A
V
--
V
D
A
--
S
G
--
K
A
L
T
K
V
I
I
E
C
C
Y
L
T
N
E
E
K
----
V
-
E
V
C
K
R
C
V
A
A
G
A
E
Y
V
K
T
S
T
G
-
F
G
T
H
G
A
T
P
E
D
V
K
L
--
M
K
D
T
-----
V
G
---
D
-----
K
---
A
L
V
K
A
A
G
G
I
R
T
F
D
D
A
M
K
M
I
N
N
------------
G
A
S
R
I
G
A
S
---------
A
G
-
I
A
I
L
N
G
I
-------
53
HHSearch
82.30
41%
-110
- C2 -
3OA3
1
?
A:
[53-272]
------
P
E
V
V
S
I
A
Q
I
I
D
H
T
Q
L
S
L
S
A
T
G
S
Q
I
D
V
L
C
A
E
A
K
E
Y
--
G
F
A
T
V
C
V
R
P
-
D
Y
V
S
-
R
A
------
V
Q
Y
L
QG-
T
----
Q
------
V
G
V
T
--
C
V
I
G
F
H
E
G
T
Y
S
T
D
Q
K
V
S
E
A
K
R
A
M
Q
N
G
A
S
E
L
D
M
V
--
M
N
Y
P
W
L
S
E
K
R
Y
T
D
V
F
Q
D
I
---
R
A
V
--
R
L
A
--
A
K
--
D
A
I
L
K
V
I
L
E
T
S
Q
L
T
A
----
D
E
I
I
-
A
G
C
V
L
S
S
L
A
G
A
D
Y
V
K
T
S
T
G
F
N
G
-
P
G
A
S
I
E
N
V
S
L
--
M
S
A
V
-----
C
D
S
LQ
S
-----
E
---
T
R
V
K
A
S
G
G
I
R
T
I
E
D
C
V
K
M
V
R
A
------------
G
A
E
R
L
G
A
S
---------
A
G
-
V
K
I
V
N
E
T
-------
12
PsiBlast_PDB
81.38
38%
-99
- C2 -
1N7K
-
DEOC_AERPE
A:
[15-232]
---
L
G
S
P
E
--
D
L
A
S
R
I
D
S
T
L
L
S
P
R
A
T
E
E
D
V
R
N
L
V
R
E
A
S
D
Y
--
G
F
R
C
A
V
L
T
P
V
Y
T
V
K
-
I
S
G
L
----
A
E
K
----
L
----
G
------
V
K
L
C
--
S
V
I
G
F
P
L
G
Q
A
P
L
E
V
K
L
V
E
A
Q
T
V
L
E
A
G
A
T
E
L
D
V
V
PH
L
S
L
G
P
------
E
A
V
Y
R
E
V
---
S
G
I
V
K
L
A
K
--
S
Y
--
G
A
V
V
K
V
I
L
E
-
A
P
L
W
D
D
K
T
L
S
L
L
V
-
D
S
S
R
R
A
---
G
A
D
I
V
K
T
S
T
G
V
Y
T
K
G
G
D
P
V
T
V
F
R
L
A
S
L
A
K
P
-----
L
G
-------------
M
G
V
K
A
S
G
G
I
R
S
G
I
D
A
V
L
A
V
G
A
------------
G
A
D
I
I
G
T
S
---------
S
A
-
V
K
V
L
E
S
F
K
------
55
HHSearch
80.13
45%
-102
- C2 -
1UB3
1
DEOC_THET8
A:
[2-212]
----------
D
L
A
A
H
I
D
H
T
L
L
K
P
T
A
T
L
E
E
V
A
K
A
A
E
E
A
L
E
Y
--
G
F
Y
G
L
C
I
P
P
-
S
Y
V
A
-
W
V
------
R
A
R
Y
---
P
HA--
P
------
F
R
L
V
--
T
V
V
G
F
P
L
G
Y
Q
E
K
E
V
K
A
L
E
A
A
L
A
C
A
R
G
A
D
E
V
D
M
V
--
L
H
L
G
R
A
K
A
G
D
L
D
Y
L
E
A
E
V
---
R
A
V
--
R
E
A
--
V
P
--
Q
A
V
L
K
V
I
L
E
T
G
Y
F
S
P
----
E
E
I
A
-
R
L
A
E
A
A
I
R
G
G
A
D
F
L
K
T
S
T
G
F
G
P
-
R
G
A
S
L
E
D
V
A
L
--
L
V
R
V
-----
A
Q
---
G
-----
R
---
A
Q
V
K
A
A
G
G
I
R
D
R
E
T
A
L
R
M
L
K
A
------------
G
A
S
R
L
G
T
S
---------
S
G
-
V
A
L
V
A
---------
7
PsiBlast_PDB
79.25
41%
-101
- C2 -
3R13
5
DEOC_THEMA
A:
[47-253]
---------------
I
E
H
T
N
L
K
P
F
A
T
P
D
D
I
K
K
L
C
L
E
A
R
E
N
--
R
F
H
G
V
C
V
N
P
-
C
Y
V
K
-
L
A
R
E
E
---
L
E
G
----
T
----
D
------
V
K
V
V
--
T
V
V
G
F
P
L
G
A
N
E
T
R
T
K
A
H
E
A
I
F
A
V
E
S
G
A
D
E
I
D
M
V
--
I
N
V
G
M
L
K
A
K
E
W
E
Y
V
Y
E
D
I
---
R
S
V
--
V
E
S
--
V
K
--
G
K
V
V
K
V
I
I
E
T
C
Y
L
----
D
T
E
E
K
I
-
A
A
C
V
I
S
K
L
A
G
A
H
F
V
K
T
S
T
G
-
F
G
T
G
G
A
T
A
E
D
V
H
L
--
M
K
W
I
-----
V
G
---
D
-----
E
---
M
G
V
K
A
S
G
G
I
R
T
F
E
D
A
V
K
M
I
M
Y
------------
G
A
D
R
I
G
T
S
---------
S
G
-
V
K
I
V
Q
G
--------
6
PsiBlast_PDB
79.01
41%
-101
- C2 -
3R12
3
DEOC_THEMA
A:
[47-253]
---------------
I
E
H
T
N
L
K
P
F
A
T
P
D
D
I
K
K
L
C
L
E
A
R
E
N
--
R
F
H
G
V
C
V
N
P
-
C
Y
V
K
-
L
A
R
E
E
---
L
E
G
----
T
----
D
------
V
K
V
V
--
T
V
V
G
F
P
L
G
A
N
E
T
R
T
K
A
H
E
A
I
F
A
V
E
S
G
A
D
E
I
D
M
V
--
I
N
V
G
M
L
K
A
K
E
W
E
Y
V
Y
E
D
I
---
R
S
V
--
V
E
S
--
V
K
--
G
K
V
V
K
V
I
I
E
T
C
Y
L
----
D
T
E
E
K
I
-
A
A
C
V
I
S
K
L
A
G
A
H
F
V
K
T
S
T
G
-
F
G
T
G
G
A
T
A
E
D
V
H
L
--
M
K
W
I
-----
V
G
---
D
-----
E
---
M
G
V
K
A
S
G
G
I
R
T
F
E
D
A
V
K
M
I
M
Y
------------
G
A
D
R
I
G
T
S
---------
S
G
-
V
K
I
V
Q
G
--------
29
PsiBlast_CBE
76.09
45%
-96
- C2 -
1UB3
1
DEOC_THET8
D:
[3-205]
-----------
L
A
A
H
I
D
H
T
L
L
K
P
T
A
T
L
E
E
V
A
K
A
A
E
E
A
L
E
Y
--
G
F
Y
G
L
C
I
P
P
-
S
Y
V
--
A
W
------
V
R
A
RYPH
A
----
P
------
F
R
L
V
--
T
V
V
G
F
P
L
G
Y
Q
E
K
E
V
K
A
L
E
A
A
L
A
C
A
R
G
A
D
E
V
D
M
V
--
L
H
L
G
R
A
K
A
G
D
L
D
Y
L
E
A
E
V
---
R
A
V
--
R
E
A
--
V
P
--
Q
A
V
L
K
V
I
L
E
T
----
G
Y
F
S
P
E
E
I
A
-
R
L
A
E
A
A
I
R
G
G
A
D
F
L
K
T
S
T
G
F
G
P
R
-
G
A
S
L
E
D
V
A
L
--
L
V
R
V
-----
A
Q
---
G
-----
R
---
A
Q
V
K
A
A
G
G
I
R
D
R
E
T
A
L
R
M
L
K
A
------------
G
A
S
R
L
G
T
S
--------------------------
31
PsiBlast_CBE
75.91
45%
-97
- C2 -
1UB3
1
DEOC_THET8
B:
[3-205]
-----------
L
A
A
H
I
D
H
T
L
L
K
P
T
A
T
L
E
E
V
A
K
A
A
E
E
A
L
E
Y
--
G
F
Y
G
L
C
I
P
P
-
S
Y
V
--
A
W
------
V
R
A
R
Y
P
H
A
----
P
------
F
R
L
V
--
T
V
V
G
F
P
L
G
Y
Q
E
K
E
V
K
A
L
E
A
A
L
A
C
A
R
G
A
D
E
V
D
M
V
--
L
H
L
G
R
A
K
A
G
D
L
D
Y
L
E
A
E
V
---
R
A
V
--
R
E
A
--
V
P
--
Q
A
V
L
K
V
I
L
E
T
----
G
Y
F
S
P
E
E
I
A
-
R
L
A
E
A
A
I
R
G
G
A
D
F
L
K
T
S
T
G
F
G
P
R
-
G
A
S
L
E
D
V
A
L
--
L
V
R
V
-----
A
Q
---
G
-----
R
---
A
Q
V
K
A
A
G
G
I
R
D
R
E
T
A
L
R
M
L
K
A
------------
G
A
S
R
L
G
T
S
--------------------------
50
HHSearch
75.90
33%
-101
- C2 -
5C5Y
3
?
A:
[7-245]
-------
V
A
Q
R
A
L
S
L
M
D
L
T
S
L
T
N
T
E
T
D
Q
E
I
I
D
L
C
R
Q
A
K
S
P
AG
E
T
A
A
I
C
I
F
P
-
R
F
I
P
-
V
A
------
K
K
A
L
K
--
A
Q
QTP
H
------
I
K
I
A
--
T
V
T
N
F
P
Q
G
N
D
D
L
D
I
A
L
A
E
T
R
A
A
V
A
Y
G
A
D
E
V
D
L
V
--
F
P
Y
R
A
L
I
Q
G
N
E
T
I
G
F
D
M
V
---
K
V
C
--
K
Q
A
--
C
S
G-
N
A
K
L
K
V
I
I
E
T
G
E
L
K
S
---
E
E
L
I
R
-
K
A
S
E
I
A
I
N
A
G
A
D
F
I
K
T
S
T
G
K
V
A
-
I
N
A
T
P
E
A
A
K
V
--
M
L
T
V
-----
I
K
N
KN
T
-----
A
---
V
G
F
K
P
A
G
G
V
R
N
A
D
D
A
A
I
Y
L
D
L
A
D
N
I
LGNEWADA
N
H
F
R
F
G
A
S
---------
S
L
L
I
S
L
L
D
T
L
-------
30
PsiBlast_CBE
75.79
45%
-96
- C2 -
1UB3
1
DEOC_THET8
C:
[3-205]
-----------
L
A
A
H
I
D
H
T
L
L
K
P
T
A
T
L
E
E
V
A
K
A
A
E
E
A
L
E
Y
--
G
F
Y
G
L
C
I
P
P
-
S
Y
V
--
A
W
------
V
R
A
RYPH
A
----
P
------
F
R
L
V
--
T
V
V
G
F
P
L
G
Y
Q
E
K
E
V
K
A
L
E
A
A
L
A
C
A
R
G
A
D
E
V
D
M
V
--
L
H
L
G
R
A
K
A
G
D
L
D
Y
L
E
A
E
V
---
R
A
V
--
R
E
A
--
V
P
--
Q
A
V
L
K
V
I
L
E
T
----
G
Y
F
S
P
E
E
I
A
-
R
L
A
E
A
A
I
R
G
G
A
D
F
L
K
T
S
T
G
F
G
P
R
-
G
A
S
L
E
D
V
A
L
--
L
V
R
V
-----
A
Q
---
G
-----
R
---
A
Q
V
K
A
A
G
G
I
R
D
R
E
T
A
L
R
M
L
K
A
------------
G
A
S
R
L
G
T
S
--------------------------
9
PsiBlast_PDB
75.60
45%
-94
- C2 -
1UB3
1
DEOC_THET8
A:
[3-205]
-----------
L
A
A
H
I
D
H
T
L
L
K
P
T
A
T
L
E
E
V
A
K
A
A
E
E
A
L
E
Y
--
G
F
Y
G
L
C
I
P
P
-
S
Y
V
--
A
W
------
V
R
A
R
Y
P
H
A
----
P
------
F
R
L
V
--
T
V
V
G
F
P
L
G
Y
Q
E
K
E
V
K
A
L
E
A
A
L
A
C
A
R
G
A
D
E
V
D
M
V
--
L
H
L
G
R
A
K
A
G
D
L
D
Y
L
E
A
E
V
---
R
A
V
--
R
E
A
--
V
P
--
Q
A
V
L
K
V
I
L
E
T
----
G
Y
F
S
P
E
E
I
A
-
R
L
A
E
A
A
I
R
G
G
A
D
F
L
K
T
S
T
G
F
G
P
R
-
G
A
S
L
E
D
V
A
L
--
L
V
R
V
-----
A
Q
---
G
-----
R
---
A
Q
V
K
A
A
G
G
I
R
D
R
E
T
A
L
R
M
L
K
A
------------
G
A
S
R
L
G
T
S
--------------------------
68
Fugue
74.49
32%
-92
- C2 -
1JCL
1
DEOC_ECOLI
A:
[1-252]
HM
T
D
L
K
A
S
S
L
R
A
L
K
L
M
D
L
T
T
L
N
D
D
D
T
D
E
K
V
I
A
L
C
H
Q
A
K
T
P
VG
N
T
A
A
I
C
I
Y
P
-
R
F
I
P
-
I
A
------
R
K
T
----
L
----
K
E
Q
GTPE
I
R
I
A
--
T
V
T
N
F
P
H
G
N
D
D
I
D
I
A
L
A
E
T
R
A
A
I
A
Y
G
A
D
E
V
D
V
V
--
F
P
Y
R
A
L
M
A
G
N
E
Q
V
G
F
D
L
V
---
K
A
C
--
K
E
A
--
C
A
A
A
N
V
L
L
K
V
I
I
E
T
G
E
L
---
K
D
E
A
L
I
R
-
K
A
S
E
I
S
I
K
A
G
A
D
F
I
K
T
S
T
G
-
K
V
A
V
N
A
T
P
E
S
A
R
I
--
M
M
E
V
-----
I
R
---
D
M
GVEK
T
---
V
G
F
K
P
A
G
G
V
R
T
A
E
D
A
Q
K
Y
L
A
I
------------
A
D
E
L
F
G
A
D
WADARHYRF
G
A
-
S
S
L
L
A
S
L
L
K
A
L
GHG
42
PsiBlast_CBE
67.48
34%
-97
- C2 -
1JCL
1
DEOC_ECOLI
B:
[15-217]
--------------
L
M
D
L
T
T
L
N
D
D
D
T
D
E
K
V
I
A
L
C
H
Q
A
K
T
P
VG
N
T
A
A
I
C
I
Y
P
-
R
F
I
P
-
I
A
RKT---
L
K
E
----
Q
----
G
TPE---
I
R
I
A
--
T
V
T
N
F
P
H
G
N
D
D
I
D
I
A
L
A
E
T
R
A
A
I
A
Y
G
A
D
E
V
D
V
V
--
F
P
Y
R
A
L
M
A
G
N
-
E
Q
V
G
F
D
L
VKA
C
K
E
--
A
C
A
--
A
A
--
N
V
L
L
K
V
I
I
E
T
G
E
L
K
D
E
A
---
L
I
R
-
K
A
S
E
I
S
I
K
A
G
A
D
F
I
K
T
S
T
G
-
K
V
A
V
N
A
T
P
E
S
A
R
I
--
M
M
E
V
IRDMG
V
E
---
K
-----
T
---
V
G
F
K
P
A
G
G
V
R
T
A
E
D
A
Q
K
Y
L
------------------------------------------------
20
PsiBlast_PDB
67.33
33%
-97
- C2 -
1JCJ
1
DEOC_ECOLI
A:
[15-217]
--------------
L
M
D
L
T
T
L
N
D
D
D
T
D
E
K
V
I
A
L
C
H
Q
A
K
T
P
VG
N
T
A
A
I
C
I
Y
P
-
R
F
I
P
-
I
A
R
K
T
---
L
K
E
----
Q
----
G
TPE---
I
R
I
A
--
T
V
T
N
F
P
H
G
N
D
D
I
D
I
A
L
A
E
T
R
A
A
I
A
Y
G
A
D
E
V
D
V
V
--
F
P
Y
R
A
L
M
A
G
N
-
E
Q
V
G
F
D
L
V
K
A
C
K
E
--
A
C
A
--
A
A
--
N
V
L
L
K
V
I
I
E
T
G
E
L
K
D
E
A
---
L
I
R
-
K
A
S
E
I
S
I
K
A
G
A
D
F
I
K
T
S
T
G
-
K
V
A
V
N
A
T
P
E
S
A
R
I
--
M
M
E
V
I
R
D
M
G
V
E
---
K
-----
T
---
V
G
F
L
P
A
G
G
V
R
T
A
E
D
A
Q
K
Y
L
------------------------------------------------
18
PsiBlast_PDB
67.07
34%
-98
- C2 -
1JCL
1
DEOC_ECOLI
A:
[15-217]
--------------
L
M
D
L
T
T
L
N
D
D
D
T
D
E
K
V
I
A
L
C
H
Q
A
K
T
P
VG
N
T
A
A
I
C
I
Y
P
-
R
F
I
P
-
I
A
R
K
T
---
L
K
E
----
Q
----
G
TPE---
I
R
I
A
--
T
V
T
N
F
P
H
G
N
D
D
I
D
I
A
L
A
E
T
R
A
A
I
A
Y
G
A
D
E
V
D
V
V
--
F
P
Y
R
A
L
M
A
G
N
-
E
Q
V
G
F
D
L
V
K
A
C
K
E
--
A
C
A
--
A
A
--
N
V
L
L
K
V
I
I
E
T
G
E
L
K
D
E
A
---
L
I
R
-
K
A
S
E
I
S
I
K
A
G
A
D
F
I
K
T
S
T
G
-
K
V
A
V
N
A
T
P
E
S
A
R
I
--
M
M
E
V
I
R
D
M
G
V
E
---
K
-----
T
---
V
G
F
K
P
A
G
G
V
R
T
A
E
D
A
Q
K
Y
L
------------------------------------------------
43
PsiBlast_CBE
66.58
33%
-96
- C2 -
1JCJ
1
DEOC_ECOLI
B:
[15-217]
--------------
L
M
D
L
T
T
L
N
D
D
D
T
D
E
K
V
I
A
L
C
H
Q
A
K
T
P
VG
N
T
A
A
I
C
I
Y
P
-
R
F
I
P
-
I
A
RKT---
L
K
E
----
Q
----
G
TPE---
I
R
I
A
--
T
V
T
N
F
P
H
G
N
D
D
I
D
I
A
L
A
E
T
R
A
A
I
A
Y
G
A
D
E
V
D
V
V
--
F
P
Y
R
A
L
M
A
G
N
-
E
Q
V
G
F
D
L
VKA
C
K
E
--
A
C
A
--
A
A
--
N
V
L
L
K
V
I
I
E
T
G
E
L
K
D
E
A
---
L
I
R
-
K
A
S
E
I
S
I
K
A
G
A
D
F
I
K
T
S
T
G
-
K
V
A
V
N
A
T
P
E
S
A
R
I
--
M
M
E
V
IRDMG
V
E
---
K
-----
T
---
V
G
F
L
P
A
G
G
V
R
T
A
E
D
A
Q
K
Y
L
------------------------------------------------
38
PsiBlast_CBE
53.50
34%
-78
- C2 -
5C5Y
3
?
D:
[45-221]
---------------------------------------------
A
I
C
I
F
P
-
R
F
I
P
-
V
A
KKALKA
Q
Q
T
----
P
----
H
------
I
K
I
A
--
T
V
T
N
F
P
Q
G
N
D
D
L
D
I
A
L
A
E
T
R
A
A
V
A
Y
G
A
D
E
V
D
L
V
--
F
P
Y
R
A
L
I
Q
G
N
-
E
T
I
G
F
D
M
---
V
K
V
CK
Q
A
C
--
S
G
--
N
A
K
L
K
V
I
I
E
T
----
G
E
L
K
S
E
E
L
I
R
K
A
S
E
I
A
I
N
A
G
A
D
F
I
K
T
S
T
G
-
K
V
A
I
N
A
T
P
E
A
A
K
V
--
M
L
T
V
-----
I
K
---
N
-----
K
NTA
V
G
F
K
P
A
G
G
V
R
N
A
D
D
A
A
I
Y
L
D
L
------------
A
D
N
I
L
G
----------------------------
16
PsiBlast_PDB
53.28
34%
-75
- C2 -
5C5Y
3
?
A:
[45-221]
---------------------------------------------
A
I
C
I
F
P
-
R
F
I
P
-
V
A
K
K
A
L
K
A
Q
Q
T
----
P
----
H
------
I
K
I
A
--
T
V
T
N
F
P
Q
G
N
D
D
L
D
I
A
L
A
E
T
R
A
A
V
A
Y
G
A
D
E
V
D
L
V
--
F
P
Y
R
A
L
I
Q
G
N
-
E
T
I
G
F
D
M
---
V
K
V
C
K
Q
A
C
--
S
G
--
N
A
K
L
K
V
I
I
E
T
----
G
E
L
K
S
E
E
L
I
R
K
A
S
E
I
A
I
N
A
G
A
D
F
I
K
T
S
T
G
-
K
V
A
I
N
A
T
P
E
A
A
K
V
--
M
L
T
V
-----
I
K
---
N
-----
K
NTA
V
G
F
K
P
A
G
G
V
R
N
A
D
D
A
A
I
Y
L
D
L
------------
A
D
N
I
L
G
----------------------------
40
PsiBlast_CBE
53.22
34%
-77
- C2 -
5C5Y
2
?
B:
[45-221]
---------------------------------------------
A
I
C
I
F
P
-
R
F
I
P
-
V
A
K
K
A
L
K
A
Q
Q
T
----
P
----
H
------
I
K
I
A
--
T
V
T
N
F
P
Q
G
N
D
D
L
D
I
A
L
A
E
T
R
A
A
V
A
Y
G
A
D
E
V
D
L
V
--
F
P
Y
R
A
L
I
Q
G
N
-
E
T
I
G
F
D
M
---
V
K
V
C
K
Q
A
C
--
S
G
--
N
A
K
L
K
V
I
I
E
T
----
G
E
L
K
S
E
E
L
I
R
K
A
S
E
I
A
I
N
A
G
A
D
F
I
K
T
S
T
G
-
K
V
A
I
N
A
T
P
E
A
A
K
V
--
M
L
T
V
-----
I
K
---
N
-----
K
NTA
V
G
F
K
P
A
G
G
V
R
N
A
D
D
A
A
I
Y
L
D
L
------------
A
D
N
I
L
G
----------------------------
39
PsiBlast_CBE
53.04
34%
-76
- C2 -
5C5Y
1
?
C:
[45-221]
---------------------------------------------
A
I
C
I
F
P
-
R
F
I
P
-
V
A
KKALKA
Q
Q
T
----
P
----
H
------
I
K
I
A
--
T
V
T
N
F
P
Q
G
N
D
D
L
D
I
A
L
A
E
T
R
A
A
V
A
Y
G
A
D
E
V
D
L
V
--
F
P
Y
R
A
L
I
Q
G
N
-
E
T
I
G
F
D
M
---
V
K
V
CK
Q
A
C
--
S
G
--
N
A
K
L
K
V
I
I
E
T
----
G
E
L
K
S
E
E
L
I
R
K
A
S
E
I
A
I
N
A
G
A
D
F
I
K
T
S
T
G
-
K
V
A
I
N
A
T
P
E
A
A
K
V
--
M
L
T
V
-----
I
K
---
N
-----
K
NTA
V
G
F
K
P
A
G
G
V
R
N
A
D
D
A
A
I
Y
L
D
L
------------
A
D
N
I
L
G
----------------------------
15
PsiBlast_PDB
52.26
34%
-70
- C2 -
5C2X
2
?
A:
[45-221]
---------------------------------------------
A
I
C
I
F
P
-
R
F
I
P
-
V
A
K
K
A
L
K
A
Q
Q
T
----
P
----
H
------
I
K
I
A
--
T
V
T
N
F
P
Q
G
N
D
D
L
D
I
A
L
A
E
T
R
A
A
V
A
Y
G
A
D
E
V
D
L
V
--
F
P
Y
R
A
L
I
Q
G
N
-
E
T
I
G
F
D
M
---
V
K
V
C
K
Q
A
C
--
S
G
--
N
A
K
L
K
V
I
I
E
T
----
G
E
L
K
S
E
E
L
I
R
K
A
S
E
I
A
I
N
A
G
A
D
F
I
K
T
S
T
G
-
K
V
A
I
N
A
T
P
E
A
A
K
V
--
M
L
T
V
-----
I
K
---
N
-----
K
NTA
V
G
F
K
P
A
G
G
V
R
N
A
D
D
A
A
I
Y
L
D
L
------------
A
D
N
I
L
G
----------------------------
41
PsiBlast_CBE
52.18
34%
-70
- C2 -
5C2X
3
?
B:
[45-221]
---------------------------------------------
A
I
C
I
F
P
-
R
F
I
P
-
V
A
KKALKA
Q
Q
T
----
P
----
H
------
I
K
I
A
--
T
V
T
N
F
P
Q
G
N
D
D
L
D
I
A
L
A
E
T
R
A
A
V
A
Y
G
A
D
E
V
D
L
V
--
F
P
Y
R
A
L
I
Q
G
N
-
E
T
I
G
F
D
M
---
V
K
V
CK
Q
A
C
--
S
G
--
N
A
K
L
K
V
I
I
E
T
----
G
E
L
K
S
E
E
L
I
R
K
A
S
E
I
A
I
N
A
G
A
D
F
I
K
T
S
T
G
-
K
V
A
I
N
A
T
P
E
A
A
K
V
--
M
L
T
V
-----
I
K
---
N
-----
K
NTA
V
G
F
K
P
A
G
G
V
R
N
A
D
D
A
A
I
Y
L
D
L
------------
A
D
N
I
L
G
----------------------------