@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv0521: (2016-04-23 )
MREAAQALGFEVLDQRDLVRNLRTHYSRVFEELEARRLELEGKSSQEYLDKMRVGLKNWVEAADNGHSRVGHPTFPRTRLTPICQLPTAAIDSTAGRRRYR
Atome Classification :
(20 SA)
---------------------.........10-..----.----.....20........30........40.--.......50........60........70........80...-----------------.....90........100------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------M
R
E
A
A
Q
A
L
G
F
E
-VL----
D
----
Q
R
D
L
V
R
N
L
R
T
H
Y
S
R
V
F
E
E
L
E
A
R
R
L
ELEG--K
S
S
Q
E
Y
L
D
K
M
R
V
G
L
K
N
W
V
E
AADNGHSRVGHPTFPRTRLTPIC-----------------QLP
T
A
AIDSTAGRRRYR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
77.33
15%
-54
- C3 -
4KRI
1
?
A:
[355-433]
---------------------
I
E
E
I
A
K
K
T
G
F
I
-
D
I
----
E
----
V
E
N
M
T
P
R
F
K
E
I
L
L
E
E
R
E
R
I
E
Q
D
K
E
T
F
L
A
--
K
F
S
Q
N
A
Y
D
G
L
V
S
G
W
K
S
K
L
Q
Y
I
A
D
D
N
H
N
W
N
F
F
A
A
V
K
P
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
76.82
29%
-17
- C3 -
2O57
-
?
A:
[218-296]
----------------------
R
S
L
A
K
E
C
G
L
V
-
T
L
----
R
----
T
F
S
R
P
D
S
L
V
H
H
Y
S
K
V
K
A
E
L
I
K
R
S
S
E
I
A
S
--
F
C
S
P
E
F
Q
A
N
M
K
R
G
L
E
H
W
I
E
G
G
R
A
G
K
L
T
W
G
G
M
L
F
R
K
S
D
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
76.75
28%
-18
- C3 -
2O57
-
?
A:
[218-294]
----------------------
R
S
L
A
K
E
C
G
L
V
-
T
L
----
R
----
T
F
S
R
P
D
S
L
V
H
H
Y
S
K
V
K
A
E
L
I
K
R
S
S
E
I
A
S
--
F
C
S
P
E
F
Q
A
N
M
K
R
G
L
E
H
W
I
E
G
G
R
A
G
K
L
T
W
G
G
M
L
F
R
K
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
75.48
21%
-40
- C3 -
1KPG
2
CMAS1_MYCTU
A:
[212-287]
----------------------
Q
E
C
A
S
A
N
G
F
T
-
V
T
----
R
----
V
Q
S
L
Q
P
H
Y
A
K
T
L
D
L
W
S
A
A
L
Q
A
N
K
G
Q
A
I
A
--
L
Q
S
E
E
V
Y
E
R
Y
M
K
Y
L
T
G
C
A
E
M
F
R
I
G
Y
I
D
V
N
Q
F
T
C
Q
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
73.77
13%
-52
- C3 -
3UJC
1
?
A:
[189-266]
---------------------
Y
A
D
I
L
T
A
C
N
F
K
-
N
V
----
V
----
S
K
D
L
S
D
Y
W
N
Q
L
L
E
V
E
H
K
Y
L
H
E
N
K
E
E
F
L
K
--
L
F
S
E
K
K
F
I
S
L
D
D
G
W
S
R
K
I
K
D
S
K
R
K
M
Q
R
W
G
Y
F
K
A
T
K
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
73.31
13%
-43
- C3 -
4INE
1
?
A:
[375-452]
----------------------
A
D
I
A
N
K
T
G
F
V
-
N
V
----
Q
----
T
E
N
M
T
P
R
F
K
E
I
L
L
E
E
R
G
H
L
E
Q
N
E
A
E
F
M
S
--
K
F
T
Q
R
E
R
D
S
L
I
S
G
W
T
D
K
L
G
Y
I
E
K
D
N
H
N
W
N
F
F
L
A
Q
K
P
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
71.51
16%
-16
- C3 -
3BUS
-
REBMT_NOCAE
A:
[200-273]
----------------------
E
S
D
V
R
Q
A
E
L
V
-
V
T
----
S
----
T
V
D
I
S
A
Q
A
R
P
S
L
V
K
T
A
E
A
F
E
N
A
R
S
Q
V
E
P
--
F
M
G
A
E
G
L
D
R
M
I
A
T
F
R
G
---
L
A
E
V
P
E
A
G
Y
V
L
I
G
A
R
K
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
71.08
16%
-54
- C3 -
3HEM
2
CMAS2_MYCTU
A:
[227-302]
----------------------
D
Y
Y
S
S
N
A
G
W
K
-
V
E
----
R
----
Y
H
R
I
G
A
N
Y
V
P
T
L
N
A
W
A
D
A
L
Q
A
H
K
D
E
A
I
A
--
L
K
G
Q
E
T
C
D
I
Y
M
H
Y
L
R
G
C
S
D
L
F
R
D
K
Y
T
D
V
C
Q
F
T
L
V
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
70.09
19%
-64
- C3 -
1OCT
2
C:
[1-96]
-----------------DLEE
L
E
Q
F
A
K
T
F
K
Q
R
-
R
I
----
K
LGFT
Q
G
D
V
G
L
A
M
G
K
L
Y
G
N
D
F
S
Q
T
T
I
S
R
F
E
-
A
L
--
N
L
S
F
K
N
M
C
K
L
K
P
L
L
E
K
W
L
N
D
A
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
69.62
10%
-56
- C3 -
4IV0
1
?
A:
[207-284]
----------------------
G
D
L
I
K
S
C
K
F
Q
-
N
V
----
E
----
A
K
D
I
S
D
Y
W
L
E
L
L
Q
L
E
L
S
K
L
E
E
K
K
E
E
F
L
K
--
V
Y
S
I
K
E
Y
N
S
L
K
D
G
W
T
R
K
I
K
D
T
K
R
D
L
Q
K
W
G
Y
F
K
A
Q
K
M
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
68.33
31%
-65
- C3 -
3L1P
2
PO5F1_MOUSE
A:
[30-85]
--------------------------------------------
Q
A
D
V
G
L
T
L
G
V
L
F
G
K
V
F
S
Q
T
T
I
S
R
F
E
-
A
L
--
Q
L
S
L
K
N
M
S
K
L
R
P
L
L
E
K
W
V
E
E
A
D
N
N
E
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
67.84
22%
-51
- C3 -
3F2E
1
?
A:
[8-90]
----------------------
F
T
A
V
A
E
Q
V
S
A
-
V
L
----
S
----
Q
Y
G
I
T
G
P
N
R
A
I
Y
Q
G
F
G
L
K
V
A
R
A
L
N
R
L
-----
G
G
G
P
A
L
V
N
M
I
N
G
L
K
A
Y
Y
I
S
A
F
N
A
N
-----
P
T
V
L
D
A
V
T
D
I
I
T
-----------------
G
S
P
T
G
Y
V
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
67.62
13%
-49
- C3 -
2FK8
-
MMAA4_MYCTU
A:
[238-316]
----------------------
V
E
H
G
E
K
A
G
F
T
-
V
P
----
E
----
P
L
S
L
R
P
H
Y
I
K
T
L
R
I
W
G
D
T
L
Q
S
N
K
D
K
A
I
E
--
V
T
S
E
E
V
Y
N
R
Y
M
K
Y
L
R
G
C
E
H
Y
F
T
D
E
M
L
D
C
S
L
V
T
Y
L
K
P
G
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_CBE
66.06
31%
-61
- C3 -
3L1P
2
B:
[30-86]
--------------------------------------------
Q
A
D
V
G
L
T
L
G
V
L
F
G
K
V
F
S
Q
T
T
I
S
R
F
E
A
L
---
Q
L
S
L
K
N
M
S
K
L
R
P
L
L
E
K
W
V
E
E
A
D
N
N
E
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
65.85
19%
-61
- C3 -
1CQT
3
B:
[8-163]
-----------------DLE
E
L
E
Q
F
A
K
T
F
K
Q
R
-
R
I
K
L
GF
T
----
Q
G
D
V
G
L
A
M
G
K
L
Y
N
D
-
F
S
Q
T
T
I
S
R
F
E
A
-
L
--
N
L
S
F
K
N
M
C
K
L
K
P
L
L
E
K
W
L
N
D
A
E
R
-
K
K
R
T
S
I
E
T
N
I
R
V
A
L
E
K
S
F
L
E
NQKTSEE
I
T
M
I
A
D
Q
L
N
M
E
K
E
V
I
R
V
W
F
C
N
R
R
Q
K
E
K
R
I
N
P-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
60.82
20%
-38
- C3 -
2WB6
2
Y102_AFV1Y
A:
[11-124]
--------------LE
S
T
S
L
Y
K
K
A
G
S
E
N
L
Y
F
Q
G
I
V
----
D
----
K
N
K
I
V
I
P
M
S
E
F
L
D
S
M
F
L
V
I
E
K
L
G
V
H
A
E
K
--
K
G
S
M
I
F
L
S
S
E
R
V
K
L
A
D
W
K
Q
L
G
------------
A
M
C
S
D
C
Y
H
C
-----------------
K
L
P
L
S
S
F
I
E
I
V
T
R
K
A
K
D
KFL
V
M
Y
N
EK
E
V
T
L
V
ARG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
60.36
15%
-18
- C3 -
1L8W
-
?
A:
[52-342]
---------------------
G
G
L
V
A
E
A
F
G
F
K
-
S
D
----
P
----
K
K
S
---
D
V
K
T
Y
F
T
T
V
A
A
K
L
E
K
T
K
T
D
L
N
S
LP
T
A
V
E
G
A
I
K
E
V
S
E
L
L
D
K
L
V
K
A
V
K
T
A
E
G
A
S
S
G
T
A
------
A
I
G
E
-----------------
V
V
A
D
A
D
A
A
K
V
A
D
K
A
S
V
K
G
I
A
K
G
I
K
E
I
V
E
A
A
GGSEKLKAVAAAKGENNKGAGKLF
G
K
A
G
AAAHGD
S
E
A
A
S
K
A
A
G
A
V
S
A
V
S
G
E
Q
I
L
S
A
I
V
T
A
A
D
AAEQ
D
G
K
K
PEEAKN
P
I
A
A
A
I
GDKDGGAEFGQDEMKK
D
D
Q
I
A
A
A
I
A
L
R
G
M
AKD
G
K
F
A
V
K
DGEKEKA
E
G
A
I
K
G
A
A
E
S
A
V
R
K
V
L
G
A
I
T
G
L
I
G
D
A
V
S
S
G
L
R
K
V
G
D
S----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
59.49
15%
-17
- C3 -
3O6X
6
?
A:
[3-728]
K
M
R
F
F
A
L
Q
E
L
SNRKP
L
E
I
T
T
P
S
N
K
L
S
D
Y
Y
A
S
H
-
V
F
----
D
----
R
K
K
M
Q
E
Y
L
P
---
K
E
A
Y
K
A
V
V
D
A
T
-
E
K
G
T
--
P
I
S
R
E
M
A
D
L
I
A
N
G
M
K
S
W
A
K
S
L
--
N
V
T
H
Y
T
H
W
F
Q
P
L
T
K
------------------------
H
D
G
F
I
E
F
G
E
D
G
E
V
I
E
R
F
S
GKLLTAWDGS
S
P
A
F
V
V
DT
T
L
C
I
PTIFIEALD
Y
K
T
P
L
L
K
A
L
A
A
V
D
K
A
A
T
E
V
C
Q
L
F
DKNIT
R
V
F
T
N
L
G
W
E
Q
E
Y
F
L
V
D
T
S
L
Y
N
A
R
PDLRLTGRTLMGHSIP
P
R
V
T
A
F
M
K
E
L
E
I
E
C
H
K
L
GIPVK
T
R
H
N
E
VAPN
Q
F
E
L
A
P
IFEN
C
N
L
A
N
D
H
N
Q
L
V
M
D
L
M
K
R
I
A
R
K
H
H
F
A
V
L
FHEKPYNG
V
N
G
S
G
K
H
N
N
W
S
L
C
T
DTGINLFAPGKNPKGN
M
L
F
L
T
F
L
V
N
V
L
M
M
V
H
K
N
Q
D
L
L
R
A
S
I
MS
A
G
N
S
H
R
LGANE
A
P
P
A
I
L
S
I
F
LGSQLSATLDEIRNRTSPFAFTGN
R
F
E
F
RAAGSSANC
A
A
A
M
I
A
I
N
A
A
M
A
N
Q
L
N
E
F
K
A
S
V
DKDE
A
I
F
R
I
L
K
E
N
I
I
A
S
ELIRFEGDGYSEEWKQ
E
A
A
R
R
GL
T
N
I
C
H
V
P
E
A
L
M
HYMD
N
Q
S
R
A
V
LIGERIFN
E
T
E
L
A
C
R
L
E
V
E
L
E
K
Y
T
M
K
V
Q
I
E
S
R
V
L
G
D
L
A
INH
I
V
P
I
A
V
S
Y
Q
N
R
L
L
E
N
L
C
R
M
K
E
I
F
S
E
E
E
Y
E
V
M
S
A
D
R
K
E
L
I
K
E
I
S
H
R
V
S
A
I
K
V
L
V
R
D
M
T
E
A
R
K
V
A
N
H
KEN
F
K
E
K
A
F
A
Y
E
E
TVRPY
L
E
S
I
R
D
H
I
D
H
L
E
M
E
IDDEIWPLPK
Y
R
E
L
L
FT
15
HHSearch
58.15
19%
-7
- C3 -
4PNE
1
?
A:
[227-301]
----------------------
L
E
S
L
R
A
A
G
F
E
-
I
L
----
D
----
W
E
D
V
S
S
R
T
R
Y
F
M
P
Q
F
A
E
E
L
A
A
H
Q
H
G
I
A
D
--
R
Y
G
P
A
V
-
A
G
W
A
A
A
V
C
D
Y
--
E
K
Y
A
H
D
M
G
Y
A
I
L
T
A
R
K
P
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
55.27
16%
-18
- C3 -
2N2U
-
?
A:
[1-77]
---------------------
M
V
D
L
K
I
D
V
S
-
D
-
D
E
----
E
----
A
E
K
I
I
R
E
I
R
E
Q
W
P
K
A
T
V
T
R
T
N
G
D
I
K
L
D
A
--
Q
T
-
E
K
E
A
E
K
M
E
K
A
V
K
K
-------------------------------------------
V
K
P
N
A
T
I
R
K
T
G
G
S
L
E
H
H
HHHH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------