@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv0928: (2016-04-27 )
MKLNRFGAAVGVLAAGALVLSACGNDDNVTGGGATTGQASAKVDCGGKKTLKASGSTAQANAMTRFVNVFEQACPGQTLNYTANGSGAGISEFNGNQTDFGGSDVPLSKDEAAAAQRRCGSPAWNLPVVFGPIAVTYNLNSVSSLNLDGPTLAKIFNGSITQWNNPAIQALNRDFTLPGERIHVVFRSDESGTTDNFQRYLQAASNGAWGKGAGKSFQGGVGEGARGNDGTSAAAKNTPGSITYNEWSFAQAQHLTMANIVTSAGGDPVAITIDSVGQTIAGATISGVGNDLVLDTDSFYRPKRPGSYPIVLATYEIVCSKYPDSQVGTAVKAFLQSTIGAGQSGLGDNGYIPIPDEFKSRLSTAVNAIA
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.--.--.....150.......160.......170.......180.......190.......200.......210-...-------.....220........230.......240.......---250---.......260....--...270.......280....-..-.290..--.....300.......310.......320.......330....--...-340.--......350.......360.......370
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MKL
N
R
F
G
A
A
V
G
V
L
A
A
G
A
L
V
L
SACGNDDNVTGGGATTGQ
A
S
A
K
VDCGGK
K
T
L
KASGSTA
Q
A
N
A
M
T
R
F
V
N
V
F
E
QACPGQ
T
L
N
Y
TANGSGAGISEFNGNQTDFGGSDVPLS
K
D
E
A
A
A
A
Q
R
RCGSPAWNL
P
V
V
F
G
P
I
A
V
T
Y
NLNS
V
S
--S--LNLDG
P
T
L
A
K
I
FNGSITQWN
N
P
A
I
Q
A
LNRDFTLPG
E
R
I
H
V
V
F
RSDESG
T
T
D
N
F
Q
R
Y
L
Q
A
ASNGAWGK--GAG-------KSFQGG-VGEGARGNDGTSAAAKNTPGS
I
T
YNEWSF---A
Q
A
---
Q
H
L
T
M
A
N
I
V
TSAGG--
D
P
V
A
I
T
IDSVGQTIAG
A
T
IS-GV-GN
D
L
V
L--DTDSFYRPKRPGSY
P
I
V
L
A
T
Y
E
I
V
CSKYPD
S
Q
V
G
T
A
V
K
A
F
L
Q
--
S
T
I-GAGQ--SGLGDNGYIPI
P
D
E
F
K
S
R
L
S
T
A
V
NAIA
1
PsiBlast_PDB
91.02
100%
-54
- C2 -
4LVQ
1
PSTS3_MYCTU
A:
[50-368]
-------------------------------------------------
T
L
K
A
S
G
S
T
A
Q
A
N
A
M
T
R
F
V
N
V
F
E
Q
A
C
P
G
Q
T
L
N
Y
T
A
N
G
S
G
A
G
I
S
E
F
N
G
N
Q
T
D
F
G
G
S
D
V
P
L
S
K
D
E
A
A
A
A
Q
R
R
C
G
S
P
A
W
N
L
P
V
V
F
G
P
I
A
V
T
Y
N
L
N
S
V
S
--
S
--
L
N
L
D
G
P
T
L
A
K
I
F
N
G
S
I
T
Q
W
N
N
P
A
I
Q
A
L
N
R
D
F
T
L
P
G
E
R
I
H
V
V
F
R
S
D
E
S
G
T
T
D
N
F
Q
R
Y
L
Q
A
A
S
N
G
A
W
G
K
--
G
A
G
-------
K
S
F
Q
G
G
-
V
G
E
G
A
R
G
N
D
G
T
S
A
A
A
K
N
T
P
G
S
I
T
Y
N
E
W
S
F
---
A
Q
A
---
Q
H
L
T
M
A
N
I
V
T
S
A
G
G
--
D
P
V
A
I
T
I
D
S
V
G
Q
T
I
A
G
A
T
I
S
-
G
V
-
G
N
D
L
V
L
--
D
T
D
S
F
Y
R
P
K
R
P
G
S
Y
P
I
V
L
A
T
Y
E
I
V
C
S
K
Y
P
D
S
Q
V
G
T
A
V
K
A
F
L
Q
--
S
T
I
-
G
A
G
Q
--
S
G
L
G
D
N
G
Y
I
P
I
P
D
E
F
K
S
R
L
S
T
A
V
N
A
--
27
HHSearch
90.61
99%
-55
- C2 -
4LVQ
1
PSTS3_MYCTU
A:
[50-368]
-------------------------------------------------
T
L
K
A
S
G
S
T
A
Q
A
N
A
M
T
R
F
V
N
V
F
E
Q
A
C
P
G
Q
T
L
N
Y
T
A
N
G
S
G
A
G
I
S
E
F
N
G
N
Q
T
D
F
G
G
S
D
V
P
L
S
K
D
E
A
A
A
A
Q
R
R
C
G
S
P
A
W
N
L
P
V
V
F
G
P
I
A
V
T
Y
N
L
N
S
V
S
--
S
--
L
N
L
D
G
P
T
L
A
K
I
F
N
G
S
I
T
Q
W
N
N
P
A
I
Q
A
L
N
R
D
F
T
L
P
G
E
R
I
H
V
V
F
R
S
D
E
S
G
T
T
D
N
F
Q
R
Y
L
Q
A
A
S
N
G
A
W
G
K
--
G
A
G
-------
K
S
F
Q
G
G
-
V
G
E
G
A
R
G
N
D
G
T
S
A
A
A
K
N
T
P
G
S
I
T
Y
N
E
W
S
F
---
A
Q
A
---
Q
H
L
T
M
A
N
I
V
T
S
A
G
G
--
D
P
V
A
I
T
I
D
S
V
G
Q
T
I
A
G
A
T
I
S
-
G
V
--
G
-
N
D
L
VL
D
T
D
S
F
Y
R
P
K
R
P
G
S
Y
P
I
V
L
A
T
Y
E
I
V
C
S
K
Y
P
D
S
Q
V
G
T
A
V
K
A
F
L
Q
--
S
T
I
-
G
A
G
Q
--
S
G
L
G
D
N
G
Y
I
P
I
P
D
E
F
K
S
R
L
S
T
A
V
N
A
--
21
PsiBlast_CBE
89.29
100%
-53
- C2 -
4LVQ
1
PSTS3_MYCTU
B:
[50-368]
-------------------------------------------------
T
L
K
A
S
G
S
T
A
Q
A
N
A
M
T
R
F
V
N
V
F
E
Q
A
C
P
G
Q
T
L
N
Y
T
A
N
G
S
G
A
G
I
S
E
F
N
G
N
Q
T
D
F
G
G
S
D
V
P
L
S
K
D
E
A
A
A
A
Q
R
R
C
G
S
P
A
W
N
L
P
V
V
F
G
P
I
A
V
T
Y
N
L
N
S
V
S
--
S
--
L
N
L
D
G
P
T
L
A
K
I
F
N
G
S
I
T
Q
W
N
N
P
A
I
Q
A
L
N
R
D
F
T
L
P
G
E
R
I
H
V
V
F
R
S
D
E
S
G
T
T
D
N
F
Q
R
Y
L
Q
A
A
S
N
G
A
W
G
K
--
G
A
G
-------
K
S
F
Q
G
G
-
V
G
E
G
A
R
G
N
D
G
T
S
A
A
A
K
N
T
P
G
S
I
T
Y
N
E
W
S
F
---
A
Q
A
---
Q
H
L
T
M
A
N
I
V
T
S
A
G
G
--
D
P
V
A
I
T
I
D
S
V
G
Q
T
I
A
G
A
T
I
S
-
G
V
-
G
N
D
L
V
L
--
D
T
D
S
F
Y
R
P
K
R
P
G
S
Y
P
I
V
L
A
T
Y
E
I
V
C
S
K
Y
P
D
S
Q
V
G
T
A
V
K
A
F
L
Q
--
S
T
I
-
G
A
G
Q
--
S
G
L
G
D
N
G
Y
I
P
I
P
D
E
F
K
S
R
L
S
T
A
V
N
A
--
10
PsiBlast_PDB
71.93
30%
-59
- C2 -
1QUK
1
PSTS_ECOLI
A:
[3-307]
-------------------------------------------------
S
L
T
G
A
G
A
T
F
P
A
P
V
Y
A
K
W
A
D
T
Y
Q
K
E
T
-
G
N
K
V
N
Y
Q
G
I
G
S
S
G
G
V
K
Q
I
I
A
N
T
V
D
F
G
A
S
D
A
P
L
S
-
D
E
K
L
A
Q
E
G
-----
L
F
Q
F
P
T
V
I
G
G
V
V
L
A
V
N
I
P
G
L
K
--
S
GE
L
V
L
D
G
K
T
L
G
D
I
Y
L
G
K
I
K
K
W
D
D
E
A
I
A
K
L
N
P
G
L
K
L
P
S
Q
N
I
A
V
V
R
R
A
N
G
S
G
T
S
F
V
F
T
S
Y
L
-
A
K
V
N
E
E
W
K
N
N
V
G
T
G
-------
S
T
V
K
W
P
-
I
G
L
G
G
K
G
N
D
G
I
A
A
F
V
Q
R
L
P
G
A
I
G
Y
V
E
Y
A
Y
---
A
K
Q
---
N
N
L
A
Y
T
K
L
I
-
S
A
D
G
--
K
P
V
S
P
T
E
E
N
F
A
N
A
A
K
G
A
D
W
S
-
K
T
F
A
Q
D
L
T
---------
N
Q
K
G
E
D
A
W
P
I
T
S
T
T
F
I
L
I
H
K
D
Q
K
K
P
E
Q
G
T
E
V
L
K
F
F
D
--
W
A
Y
-
K
T
G
A
--
K
Q
A
N
D
L
D
Y
A
S
L
P
D
S
V
V
E
Q
V
R
A
A
-----
15
PsiBlast_PDB
71.63
30%
-61
- C2 -
1QUJ
2
PSTS_ECOLI
A:
[3-307]
-------------------------------------------------
S
L
T
G
A
G
A
T
F
P
A
P
V
Y
A
K
W
A
D
T
Y
Q
K
E
T
-
G
N
K
V
N
Y
Q
G
I
G
S
S
G
G
V
K
Q
I
I
A
N
T
V
D
F
G
A
S
D
A
P
L
S
-
D
E
K
L
A
Q
E
G
-----
L
F
Q
F
P
T
V
I
G
G
V
V
L
A
V
N
I
P
G
L
K
--
S
GE
L
V
L
D
G
K
T
L
G
D
I
Y
L
G
K
I
K
K
W
D
D
E
A
I
A
K
L
N
P
G
L
K
L
P
S
Q
N
I
A
V
V
R
R
A
G
G
S
G
T
S
F
V
F
T
S
Y
L
-
A
K
V
N
E
E
W
K
N
N
V
G
T
G
-------
S
T
V
K
W
P
-
I
G
L
G
G
K
G
N
D
G
I
A
A
F
V
Q
R
L
P
G
A
I
G
Y
V
E
Y
A
Y
---
A
K
Q
---
N
N
L
A
Y
T
K
L
I
-
S
A
D
G
--
K
P
V
S
P
T
E
E
N
F
A
N
A
A
K
G
A
D
W
S
-
K
T
F
A
Q
D
L
T
---------
N
Q
K
G
E
D
A
W
P
I
T
S
T
T
F
I
L
I
H
K
D
Q
K
K
P
E
Q
G
T
E
V
L
K
F
F
D
--
W
A
Y
-
K
T
G
A
--
K
Q
A
N
D
L
D
Y
A
S
L
P
D
S
V
V
E
Q
V
R
A
A
-----
12
PsiBlast_PDB
71.37
30%
-61
- C2 -
1PBP
1
PSTS_ECOLI
A:
[3-307]
-------------------------------------------------
S
L
T
G
A
G
A
T
F
P
A
P
V
Y
A
K
W
A
D
T
Y
Q
K
E
T
-
G
N
K
V
N
Y
Q
G
I
G
S
S
G
G
V
K
Q
I
I
A
N
T
V
D
F
G
A
S
D
A
P
L
S
-
D
E
K
L
A
Q
E
G
-----
L
F
Q
F
P
T
V
I
G
G
V
V
L
A
V
N
I
P
G
L
K
--
S
GE
L
V
L
D
G
K
T
L
G
D
I
Y
L
G
K
I
K
K
W
D
D
E
A
I
A
K
L
N
P
G
L
K
L
P
S
Q
N
I
A
V
V
R
R
A
D
G
S
G
D
S
F
V
F
T
S
Y
L
-
A
K
V
N
E
E
W
K
N
NV
G
T
G
-------
S
T
V
K
W
P
-
I
G
L
G
G
K
G
N
D
G
I
A
A
F
V
Q
R
L
P
G
A
I
G
Y
V
E
Y
A
Y
---
A
K
Q
---
N
N
L
A
Y
T
K
L
I
-
S
A
D
G
--
K
P
V
S
P
T
E
E
N
F
A
N
A
A
K
G
A
D
W
S
-
K
T
F
A
Q
D
L
T
---------
N
Q
K
G
E
D
A
W
P
I
T
S
T
T
F
I
L
I
H
K
D
Q
K
K
P
E
Q
G
T
E
V
L
K
F
F
D
--
W
A
Y
-
K
T
G
A
--
K
Q
A
N
D
L
D
Y
A
S
L
P
D
S
V
V
E
Q
V
R
A
A
-----
3
PsiBlast_PDB
71.32
30%
-62
- C2 -
1IXH
1
PSTS_ECOLI
A:
[3-307]
-------------------------------------------------
S
L
T
G
A
G
A
T
F
P
A
P
V
Y
A
K
W
A
D
T
Y
Q
K
E
T
-
G
N
K
V
N
Y
Q
G
I
G
S
S
G
G
V
K
Q
I
I
A
N
T
V
D
F
G
A
S
D
A
P
L
S
-
D
E
K
L
A
Q
E
G
-----
L
F
Q
F
P
T
V
I
G
G
V
V
L
A
V
N
I
P
G
L
K
--
S
GE
L
V
L
D
G
K
T
L
G
D
I
Y
L
G
K
I
K
K
W
D
D
E
A
I
A
K
L
N
P
G
L
K
L
P
S
Q
N
I
A
V
V
R
R
A
D
G
S
G
T
S
F
V
F
T
S
Y
L
-
A
K
V
N
E
E
W
K
N
NV
G
T
G
-------
S
T
V
K
W
P
-
I
G
L
G
G
K
G
N
D
G
I
A
A
F
V
Q
R
L
P
G
A
I
G
Y
V
E
Y
A
Y
---
A
K
Q
---
N
N
L
A
Y
T
K
L
I
-
S
A
D
G
--
K
P
V
S
P
T
E
E
N
F
A
N
A
A
K
G
A
D
W
S
-
K
T
F
A
Q
D
L
T
---------
N
Q
K
G
E
D
A
W
P
I
T
S
T
T
F
I
L
I
H
K
D
Q
K
K
P
E
Q
G
T
E
V
L
K
F
F
D
--
W
A
Y
-
K
T
G
A
--
K
Q
A
N
D
L
D
Y
A
S
L
P
D
S
V
V
E
Q
V
R
A
A
-----
14
PsiBlast_PDB
71.30
30%
-60
- C2 -
1QUI
2
PSTS_ECOLI
A:
[3-307]
-------------------------------------------------
S
L
T
G
A
G
A
T
F
P
A
P
V
Y
A
K
W
A
D
T
Y
Q
K
E
T
-
G
N
K
V
N
Y
Q
G
I
G
S
S
G
G
V
K
Q
I
I
A
N
T
V
D
F
G
A
S
D
A
P
L
S
-
D
E
K
L
A
Q
E
G
-----
L
F
Q
F
P
T
V
I
G
G
V
V
L
A
V
N
I
P
G
L
K
--
S
GE
L
V
L
D
G
K
T
L
G
D
I
Y
L
G
K
I
K
K
W
D
D
E
A
I
A
K
L
N
P
G
L
K
L
P
S
Q
N
I
A
V
V
R
R
A
G
G
S
G
T
S
F
V
F
T
S
Y
L
-
A
K
V
N
E
E
W
K
N
N
V
G
T
G
-------
S
T
V
K
W
P
-
I
G
L
G
G
K
G
N
D
G
I
A
A
F
V
Q
R
L
P
G
A
I
G
Y
V
E
Y
A
Y
---
A
K
Q
---
N
N
L
A
Y
T
K
L
I
-
S
A
D
G
--
K
P
V
S
P
T
E
E
N
F
A
N
A
A
K
G
A
D
W
S
-
K
T
F
A
Q
D
L
T
---------
N
Q
K
G
E
D
A
W
P
I
T
S
T
T
F
I
L
I
H
K
D
Q
K
K
P
E
Q
G
T
E
V
L
K
F
F
D
--
W
A
Y
-
K
T
G
A
--
K
Q
A
N
D
L
D
Y
A
S
L
P
D
S
V
V
E
Q
V
R
A
A
-----
5
PsiBlast_PDB
71.24
30%
-62
- C2 -
1A54
2
PSTS_ECOLI
A:
[3-307]
-------------------------------------------------
S
L
T
G
A
G
A
T
F
P
A
P
V
Y
A
K
W
A
D
T
Y
Q
K
E
T
-
G
N
K
V
N
Y
Q
G
I
G
S
S
G
G
V
K
Q
I
I
A
N
T
V
D
F
G
A
S
D
A
P
L
S
-
D
E
K
L
A
Q
E
G
-----
L
F
Q
F
P
T
V
I
G
G
V
V
L
A
V
N
I
P
G
L
K
--
S
GE
L
V
L
D
G
K
T
L
G
D
I
Y
L
G
K
I
K
K
W
D
D
E
A
I
A
K
L
N
P
G
L
K
L
P
S
Q
N
I
A
V
V
R
R
A
D
G
S
G
T
S
F
V
F
T
S
Y
L
-
A
K
V
N
E
E
W
K
N
NV
G
T
G
-------
S
T
V
K
W
P
-
I
G
L
G
G
K
G
N
D
G
I
A
A
F
V
Q
R
L
P
G
A
I
G
Y
V
E
Y
C
Y
---
A
K
Q
---
N
N
L
A
Y
T
K
L
I
-
S
A
D
G
--
K
P
V
S
P
T
E
E
N
F
A
N
A
A
K
G
A
D
W
S
-
K
T
F
A
Q
D
L
T
---------
N
Q
K
G
E
D
A
W
P
I
T
S
T
T
F
I
L
I
H
K
D
Q
K
K
P
E
Q
G
T
E
V
L
K
F
F
D
--
W
A
Y
-
K
T
G
A
--
K
Q
A
N
D
L
D
Y
A
S
L
P
D
S
V
V
E
Q
V
R
A
A
-----
2
PsiBlast_PDB
71.15
30%
-59
- C2 -
2ABH
1
PSTS_ECOLI
A:
[3-307]
-------------------------------------------------
S
L
T
G
A
G
A
T
F
P
A
P
V
Y
A
K
W
A
D
T
Y
Q
K
E
T
-
G
N
K
V
N
Y
Q
G
I
G
S
S
G
G
V
K
Q
I
I
A
N
T
V
D
F
G
A
S
D
A
P
L
S
-
D
E
K
L
A
Q
E
G
-----
L
F
Q
F
P
T
V
I
G
G
V
V
L
A
V
N
I
P
G
L
K
--
S
GE
L
V
L
D
G
K
T
L
G
D
I
Y
L
G
K
I
K
K
W
D
D
E
A
I
A
K
L
N
P
G
L
K
L
P
S
Q
N
I
A
V
V
R
R
A
D
G
S
G
T
S
F
V
F
T
S
Y
L
-
A
K
V
N
E
E
W
K
N
N
V
G
T
G
-------
S
T
V
K
W
P
-
I
G
L
G
G
K
G
N
D
G
I
A
A
F
V
Q
R
L
P
G
A
I
G
Y
V
E
Y
A
Y
---
A
K
Q
---
N
N
L
A
Y
T
K
L
I
-
S
A
D
G
--
K
P
V
S
P
T
E
E
N
F
A
N
A
A
K
G
A
D
W
S
-
K
T
F
A
Q
D
L
T
---------
N
Q
K
G
E
D
A
W
P
I
T
S
T
T
F
I
L
I
H
K
D
Q
K
K
P
E
Q
G
T
E
V
L
K
F
F
D
--
W
A
Y
-
K
T
G
A
--
K
Q
A
N
D
L
D
Y
A
S
L
P
D
S
V
V
E
Q
V
R
A
A
-----
7
PsiBlast_PDB
71.14
30%
-59
- C2 -
1A40
1
PSTS_ECOLI
A:
[3-307]
-------------------------------------------------
S
L
T
G
A
G
A
T
F
P
A
P
V
Y
A
K
W
A
D
T
Y
Q
K
E
T
-
G
N
K
V
N
Y
Q
G
I
G
S
S
G
G
V
K
Q
I
I
A
N
T
V
D
F
G
A
S
D
A
P
L
S
-
D
E
K
L
A
Q
E
G
L
F
-----
Q
F
P
T
V
I
G
G
V
V
L
A
V
N
I
P
G
L
K
--
S
GE
L
V
L
D
G
K
T
L
G
D
I
Y
L
G
K
I
K
K
W
D
D
E
A
I
A
K
L
N
P
G
L
K
L
P
S
Q
N
I
A
V
V
R
R
A
D
G
S
G
T
S
F
V
F
T
S
Y
L
-
A
K
V
N
E
E
W
K
N
NV
G
T
G
-------
S
T
V
K
W
P
-
I
G
L
G
G
K
G
N
D
G
I
A
A
F
V
Q
R
L
P
G
A
I
G
Y
V
E
Y
W
Y
---
A
K
Q
---
N
N
L
A
Y
T
K
L
I
-
S
A
D
G
--
K
P
V
S
P
T
E
E
N
F
A
N
A
A
K
G
A
D
W
S
-
K
T
F
A
Q
D
L
T
---------
N
Q
K
G
E
D
A
W
P
I
T
S
T
T
F
I
L
I
H
K
D
Q
K
K
P
E
Q
G
T
E
V
L
K
F
F
D
--
W
A
Y
-
K
T
G
A
--
K
Q
A
N
D
L
D
Y
A
S
L
P
D
S
V
V
E
Q
V
R
A
A
-----
9
PsiBlast_PDB
70.86
30%
-59
- C2 -
1IXI
1
PSTS_ECOLI
A:
[3-307]
-------------------------------------------------
S
L
T
G
A
G
A
T
F
P
A
P
V
Y
A
K
W
A
D
T
Y
Q
K
E
T
-
G
N
K
V
N
Y
Q
G
I
G
S
S
G
G
V
K
Q
I
I
A
N
T
V
D
F
G
A
S
N
A
P
L
S
-
D
E
K
L
A
Q
E
G
-----
L
F
Q
F
P
T
V
I
G
G
V
V
L
A
V
N
I
P
G
L
K
--
S
GE
L
V
L
D
G
K
T
L
G
D
I
Y
L
G
K
I
K
K
W
D
D
E
A
I
A
K
L
N
P
G
L
K
L
P
S
Q
N
I
A
V
V
R
R
A
D
G
S
G
T
S
F
V
F
T
S
Y
L
-
A
K
V
N
E
E
W
K
N
N
V
G
T
G
-------
S
T
V
K
W
P
-
I
G
L
G
G
K
G
N
D
G
I
A
A
F
V
Q
R
L
P
G
A
I
G
Y
V
E
Y
A
Y
---
A
K
Q
---
N
N
L
A
Y
T
K
L
I
-
S
A
D
G
--
K
P
V
S
P
T
E
E
N
F
A
N
A
A
K
G
A
D
W
S
-
K
T
F
A
Q
D
L
T
---------
N
Q
K
G
E
D
A
W
P
I
T
S
T
T
F
I
L
I
H
K
D
Q
K
K
P
E
Q
G
T
E
V
L
K
F
F
D
--
W
A
Y
-
K
T
G
A
--
K
Q
A
N
D
L
D
Y
A
S
L
P
D
S
V
V
E
Q
V
R
A
A
-----
6
PsiBlast_PDB
70.75
30%
-60
- C2 -
1A55
1
PSTS_ECOLI
A:
[3-307]
-------------------------------------------------
S
L
T
G
A
G
A
T
F
P
A
P
V
Y
A
K
W
A
D
T
Y
Q
K
E
T
-
G
N
K
V
N
Y
Q
G
I
G
S
S
G
G
V
K
Q
I
I
A
N
T
V
D
F
G
A
S
D
A
P
L
S
-
D
E
K
L
A
Q
E
G
-----
L
F
Q
F
P
T
V
I
G
G
V
V
L
A
V
N
I
P
G
L
K
--
S
GE
L
V
L
D
G
K
T
L
G
D
I
Y
L
G
K
I
K
K
W
D
D
E
A
I
A
K
L
N
P
G
L
K
L
P
S
Q
N
I
A
V
V
R
R
A
D
G
S
G
T
S
F
V
F
T
S
Y
L
-
A
K
V
N
E
E
W
K
N
N
V
G
T
G
-------
S
T
V
K
W
P
-
I
G
L
G
G
K
G
N
D
G
I
A
A
F
V
Q
R
L
P
G
A
I
G
Y
V
E
Y
C
Y
---
A
K
Q
---
N
N
L
A
Y
T
K
L
I
-
S
A
D
G
--
K
P
V
S
P
T
E
E
N
F
A
N
A
A
K
G
A
D
W
S
-
K
T
F
A
Q
D
L
T
---------
N
Q
K
G
E
D
A
W
P
I
T
S
T
T
F
I
L
I
H
K
D
Q
K
K
P
E
Q
G
T
E
V
L
K
F
F
D
--
W
A
Y
-
K
T
G
A
--
K
Q
A
N
D
L
D
Y
A
S
L
P
D
S
V
V
E
Q
V
R
A
A
-----
11
PsiBlast_PDB
70.69
30%
-68
- C2 -
1OIB
-
PSTS_ECOLI
A:
[3-307]
-------------------------------------------------
S
L
T
G
A
G
A
T
F
P
A
P
V
Y
A
K
W
A
D
T
Y
Q
K
E
T
-
G
N
K
V
N
Y
Q
G
I
G
S
S
G
G
V
K
Q
I
I
A
N
T
V
D
F
G
A
S
D
A
P
L
S
-
D
E
K
L
A
Q
E
G
-----
L
F
Q
F
P
T
V
I
G
G
V
V
L
A
V
N
I
P
G
L
K
--
S
GE
L
V
L
D
G
K
T
L
G
D
I
Y
L
G
K
I
K
K
W
D
D
E
A
I
A
K
L
N
P
G
L
K
L
P
S
Q
N
I
A
V
V
R
R
A
D
G
S
G
D
S
F
V
F
T
S
Y
L
-
A
K
V
N
E
E
W
K
N
NV
G
T
G
-------
S
T
V
K
W
P
-
I
G
L
G
G
K
G
N
D
G
I
A
A
F
V
Q
R
L
P
G
A
I
G
Y
V
E
Y
A
Y
---
A
K
Q
---
N
N
L
A
Y
T
K
L
I
-
S
A
D
G
--
K
P
V
S
P
T
E
E
N
F
A
N
A
A
K
G
A
D
W
S
-
K
T
F
A
Q
D
L
T
---------
N
Q
K
G
E
D
A
W
P
I
T
S
T
T
F
I
L
I
H
K
D
Q
K
K
P
E
Q
G
T
E
V
L
K
F
F
D
--
W
A
Y
-
K
T
G
A
--
K
Q
A
N
D
L
D
Y
A
S
L
P
D
S
V
V
E
Q
V
R
A
A
-----
30
HHSearch
70.59
29%
-58
- C2 -
1IXH
1
PSTS_ECOLI
A:
[1-310]
-----------------------------------------------
E
A
S
L
T
G
A
G
A
T
F
P
A
P
V
Y
A
K
W
A
D
T
Y
Q
K
E
T
-
G
N
K
V
N
Y
Q
G
I
G
S
S
G
G
V
K
Q
I
I
A
N
T
V
D
F
G
A
S
D
A
P
L
S
D
E
K
L
A
------
Q
E
G
L
F
Q
F
P
T
V
I
G
G
V
V
L
A
V
N
I
P
G
L
K
SG
E
--
L
V
L
D
G
K
T
L
G
D
I
Y
L
G
K
I
K
K
W
D
D
E
A
I
A
K
L
N
P
G
L
K
L
P
S
Q
N
I
A
V
V
R
R
A
D
G
S
G
T
S
F
V
F
T
S
Y
L
A
K
V
N
E
E
-
W
K
N
--
N
V
G
TGST---
V
K
W
P
I
G
---
L
G
G
K
G
N
D
G
I
A
A
F
V
Q
R
L
P
G
A
I
G
Y
V
E
Y
A
Y
---
A
K
Q
---
N
N
L
A
Y
T
K
L
I
S
-
A
D
G
--
K
P
V
S
P
T
E
E
N
F
A
N
A
A
K
G
A
D
-
W
-
S
K
----
T
-
F
--
A
-
Q
D
L
T
N
Q
K
G
E
D
A
W
P
I
T
S
T
T
F
I
L
I
H
K
D
Q
K
K
P
E
Q
G
T
E
V
L
K
F
F
D
--
W
A
Y
-
K
T
G
A
--
K
Q
A
N
D
L
D
Y
A
S
L
P
D
S
V
V
E
Q
V
R
A
A
W
K
T
--
8
PsiBlast_PDB
70.59
30%
-60
- C2 -
1IXG
1
PSTS_ECOLI
A:
[3-307]
-------------------------------------------------
S
L
T
G
A
G
A
T
F
P
A
P
V
Y
A
K
W
A
D
T
Y
Q
K
E
T
-
G
N
K
V
N
Y
Q
G
I
G
S
S
G
G
V
K
Q
I
I
A
N
T
V
D
F
G
A
S
D
A
P
L
S
-
D
E
K
L
A
Q
E
G
-----
L
F
Q
F
P
T
V
I
G
G
V
V
L
A
V
N
I
P
G
L
K
--
S
GE
L
V
L
D
G
K
T
L
G
D
I
Y
L
G
K
I
K
K
W
D
D
E
A
I
A
K
L
N
P
G
L
K
L
P
S
Q
N
I
A
V
V
R
R
A
D
G
S
G
D
S
F
V
F
T
S
Y
L
-
A
K
V
N
E
E
W
K
N
NV
G
T
G
-------
S
T
V
K
W
P
-
I
G
L
G
G
K
G
N
D
G
I
A
A
F
V
Q
R
L
P
G
A
I
G
Y
V
E
Y
A
Y
---
A
K
Q
---
N
N
L
A
Y
T
K
L
I
-
S
A
D
G
--
K
P
V
S
P
T
E
E
N
F
A
N
A
A
K
G
A
D
W
S
-
K
T
F
A
Q
D
L
T
---------
N
Q
K
G
E
D
A
W
P
I
T
S
T
T
F
I
L
I
H
K
D
Q
K
K
P
E
Q
G
T
E
V
L
K
F
F
D
--
W
A
Y
-
K
T
G
A
--
K
Q
A
N
D
L
D
Y
A
S
L
P
D
S
V
V
E
Q
V
R
A
A
-----
13
PsiBlast_PDB
70.49
30%
-62
- C2 -
1QUL
2
PSTS_ECOLI
A:
[3-307]
-------------------------------------------------
S
L
T
G
A
G
A
T
F
P
A
P
V
Y
A
K
W
A
D
T
Y
Q
K
E
T
-
G
N
K
V
N
Y
Q
G
I
G
S
S
G
G
V
K
Q
I
I
A
N
T
V
D
F
G
A
S
D
A
P
L
S
-
D
E
K
L
A
Q
E
G
-----
L
F
Q
F
P
T
V
I
G
G
V
V
L
A
V
N
I
P
G
L
K
--
S
GE
L
V
L
D
G
K
T
L
G
D
I
Y
L
G
K
I
K
K
W
D
D
E
A
I
A
K
L
N
P
G
L
K
L
P
S
Q
N
I
A
V
V
R
R
A
T
G
S
G
T
S
F
V
F
T
S
Y
L
-
A
K
V
N
E
E
W
K
N
NV
G
T
G
-------
S
T
V
K
W
P
-
I
G
L
G
G
K
G
N
D
G
I
A
A
F
V
Q
R
L
P
G
A
I
G
Y
V
E
Y
A
Y
---
A
K
Q
---
N
N
L
A
Y
T
K
L
I
-
S
A
D
G
--
K
P
V
S
P
T
E
E
N
F
A
N
A
A
K
G
A
D
W
S
-
K
T
F
A
Q
D
L
T
---------
N
Q
K
G
E
D
A
W
P
I
T
S
T
T
F
I
L
I
H
K
D
Q
K
K
P
E
Q
G
T
E
V
L
K
F
F
D
--
W
A
Y
-
K
T
G
A
--
K
Q
A
N
D
L
D
Y
A
S
L
P
D
S
V
V
E
Q
V
R
A
A
-----
28
HHSearch
68.75
29%
-55
- C2 -
1PC3
1
PSTS1_MYCTU
A:
[20-348]
-----------------------------------------
T
T
P
A
S
S
P
V
T
L
A
E
T
G
S
T
L
L
Y
P
L
F
N
L
W
G
P
A
F
H
E
R
Y
P
N
V
T
I
T
A
Q
G
T
G
S
G
A
G
I
A
Q
A
A
A
G
T
V
N
I
G
A
S
D
A
Y
L
S
E
G
D
M
A
A
H
-----
K
G
L
M
N
I
A
L
A
I
S
A
Q
Q
V
N
Y
N
L
P
G
V
S
E-
H
--
L
K
L
N
G
K
V
L
A
A
M
Y
Q
G
T
I
K
T
W
D
D
P
Q
I
A
A
L
N
P
G
V
N
L
P
G
T
A
V
V
P
L
H
R
S
D
G
S
G
D
T
F
L
F
T
Q
Y
L
S
K
Q
D
P
E
G
W
G
K
--
S
P
G
FGTT---
V
D
F
P
A
V
P
G
A
L
G
E
N
G
N
G
G
M
V
T
G
C
A
E
T
P
G
C
V
A
Y
I
G
I
S
F
---
L
D
Q
A
S
Q
R
G
L
G
E
A
Q
L
G
N
-
S
S
G
--
N
F
L
L
P
D
A
Q
S
I
Q
A
A
A
A
G
F
A
S
K
-
T
---
P
A
-
N
Q
---
A
I
S
M
I
D
G
P
A
P
D
G
Y
P
I
I
N
Y
E
Y
A
I
V
N
N
R
Q
K
D
A
A
T
A
Q
T
L
Q
A
F
L
H
--
W
A
I
T
D
G
N
K
A-
S
F
L
D
Q
V
H
F
Q
P
L
P
P
A
V
V
K
L
S
D
A
L
I
A
T
I
-
22
PsiBlast_CBE
68.22
32%
-55
- C2 -
2Z22
1
?
A:
[3-307]
-------------------------------------------------
S
L
T
G
A
G
A
T
F
P
A
P
V
Y
A
K
W
A
D
S
Y
Q
K
E
T
-
G
N
K
I
N
Y
Q
G
I
G
S
S
G
G
V
K
Q
I
I
A
N
T
V
D
F
G
A
S
D
A
P
L
T
-
D
E
K
L
A
T
E
G
L
F
-----
Q
F
P
T
V
I
G
G
V
V
L
A
V
N
I
P
G
I
K
--
S
GE
L
T
L
D
G
K
T
L
G
D
I
Y
L
G
T
V
K
K
W
N
D
P
A
I
V
K
L
N
P
G
V
K
L
P
D
Q
N
I
A
V
V
R
R
A
D
G
S
G
T
S
F
V
F
T
S
Y
L
-
A
K
V
N
A
E
W
K
E
K
V
G
A
G
-------
S
T
V
N
W
P
-
T
G
L
G
G
K
G
N
D
G
I
A
A
F
V
Q
R
L
P
G
S
I
G
Y
V
E
Y
A
Y
---
A
K
Q
---
N
N
L
A
Y
T
K
L
I
-
S
A
D
G
--
K
P
V
S
P
T
E
H
S
F
S
S
A
A
K
G
V
D
W
S
K
S
F
-
A
Q
D
L
T
---------
N
Q
K
G
D
D
V
W
P
I
T
S
T
T
F
I
L
V
H
K
E
Q
K
N
A
A
N
G
T
E
V
L
K
F
F
D
W
G
Y
T
H
-
G
A
K
Q
--
A
N
E
L
D
--
Y
A
T
L
P
A
E
V
V
E
Q
V
R
A
A
-----
16
PsiBlast_PDB
64.22
30%
-38
- C2 -
1PC3
1
PSTS1_MYCTU
A:
[18-334]
---------------------------------------
V
A
T
T
P
A
S
S
P
V
T
L
A
E
T
G
S
T
L
L
Y
P
L
F
N
L
W
G
P
A
F
H
E
R
Y
P
N
V
T
I
T
A
Q
G
T
G
S
G
A
G
I
A
Q
A
A
A
G
T
V
N
I
G
A
S
D
A
Y
L
S
E
G
D
M
A
A
H
K
G
L
M
-----
N
I
A
L
A
I
S
A
Q
Q
V
N
Y
N
L
P
G
V
S
--
E
H-
L
K
L
N
G
K
V
L
A
A
M
Y
Q
G
T
I
K
T
W
D
D
P
Q
I
A
A
L
N
P
G
V
N
L
P
G
T
A
V
V
P
L
H
R
S
D
G
S
G
D
T
F
L
F
T
Q
Y
L
S
K
Q
D
P
E
G
W
G
K
--
S
P
G
FGTTVDF
P
A
V
P
G
A
-
L
G
E
--
N
G
N
G
G
M
V
T
G
C
A
E
T
P
G
C
V
A
Y
I
G
I
S
F
L
D
Q
A
S
Q
---
R
G
L
G
E
A
Q
L
G
N
S
S
G
N
F
L
L
P
D
A
Q
S
I
Q
A
A
A
A
G
F
A
S
K
T
P
A
-----
N
Q
A
I
S
--
M
I
D
G
----
P
A
P
D
G
Y
P
I
I
N
Y
E
Y
A
I
V
N
N
R
Q
K
D
A
A
T
A
Q
T
L
Q
A
F
L
H
--
W
A
I
-
T
D
G
N
KA
S
F
L
D
Q
V
H
F
Q
P
L
P
---------------